LOCUS       DASHXG010000001       110366 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.001, whole genome shotgun sequence.
ACCESSION   DASHXG010000001 DASHXG010000000
VERSION     DASHXG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 110366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.001"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            212..604
                     /locus_tag="U2R59_000001"
     CDS             212..604
                     /locus_tag="U2R59_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8964436.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="U2R59_000002"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="U2R59_000002"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEM8964437.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3155..4765
                     /locus_tag="U2R59_000003"
     CDS             3155..4765
                     /locus_tag="U2R59_000003"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEM8964438.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5057..5926
                     /locus_tag="U2R59_000004"
     CDS             5057..5926
                     /locus_tag="U2R59_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEM8964439.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6091..7362
                     /locus_tag="U2R59_000005"
     CDS             6091..7362
                     /locus_tag="U2R59_000005"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEM8964440.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7359..8654
                     /gene="rho"
                     /locus_tag="U2R59_000006"
     CDS             7359..8654
                     /gene="rho"
                     /locus_tag="U2R59_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HEM8964441.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8753..9016
                     /locus_tag="U2R59_000007"
     CDS             8753..9016
                     /locus_tag="U2R59_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEM8964442.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9461..9910
                     /locus_tag="U2R59_000008"
     CDS             9461..9910
                     /locus_tag="U2R59_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8964443.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9967..11385
                     /locus_tag="U2R59_000009"
     CDS             9967..11385
                     /locus_tag="U2R59_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8964444.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11385..12245
                     /locus_tag="U2R59_000010"
     CDS             11385..12245
                     /locus_tag="U2R59_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HEM8964445.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12419..13192
                     /locus_tag="U2R59_000011"
     CDS             12419..13192
                     /locus_tag="U2R59_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8964446.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13339..13704
                     /locus_tag="U2R59_000012"
     CDS             13339..13704
                     /locus_tag="U2R59_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HEM8964447.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13852..15060)
                     /locus_tag="U2R59_000013"
     CDS             complement(13852..15060)
                     /locus_tag="U2R59_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8964448.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15079..15357)
                     /locus_tag="U2R59_000014"
     CDS             complement(15079..15357)
                     /locus_tag="U2R59_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964449.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15511..16206
                     /locus_tag="U2R59_000015"
     CDS             15511..16206
                     /locus_tag="U2R59_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8964450.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16648..17445)
                     /locus_tag="U2R59_000016"
     CDS             complement(16648..17445)
                     /locus_tag="U2R59_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HEM8964451.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17442..18626)
                     /locus_tag="U2R59_000017"
     CDS             complement(17442..18626)
                     /locus_tag="U2R59_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEM8964452.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18651..19898)
                     /locus_tag="U2R59_000018"
     CDS             complement(18651..19898)
                     /locus_tag="U2R59_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEM8964453.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20113..21858
                     /gene="dnaX"
                     /locus_tag="U2R59_000019"
     CDS             20113..21858
                     /gene="dnaX"
                     /locus_tag="U2R59_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEM8964454.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21878..22192
                     /locus_tag="U2R59_000020"
     CDS             21878..22192
                     /locus_tag="U2R59_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEM8964455.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22217..22813
                     /gene="recR"
                     /locus_tag="U2R59_000021"
     CDS             22217..22813
                     /gene="recR"
                     /locus_tag="U2R59_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEM8964456.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22877..23521
                     /locus_tag="U2R59_000022"
     CDS             22877..23521
                     /locus_tag="U2R59_000022"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEM8964457.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23536..23865
                     /locus_tag="U2R59_000023"
     CDS             23536..23865
                     /locus_tag="U2R59_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HEM8964458.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23879..24817
                     /gene="holB"
                     /locus_tag="U2R59_000024"
     CDS             23879..24817
                     /gene="holB"
                     /locus_tag="U2R59_000024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEM8964459.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24853..25677
                     /locus_tag="U2R59_000025"
     CDS             24853..25677
                     /locus_tag="U2R59_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HEM8964460.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25670..26017
                     /locus_tag="U2R59_000026"
     CDS             25670..26017
                     /locus_tag="U2R59_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEM8964461.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26086..26958
                     /gene="rsmI"
                     /locus_tag="U2R59_000027"
     CDS             26086..26958
                     /gene="rsmI"
                     /locus_tag="U2R59_000027"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEM8964462.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27067..28188
                     /gene="dinB"
                     /locus_tag="U2R59_000028"
     CDS             27067..28188
                     /gene="dinB"
                     /locus_tag="U2R59_000028"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEM8964463.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28242..28844)
                     /gene="nrdG"
                     /locus_tag="U2R59_000029"
     CDS             complement(28242..28844)
                     /gene="nrdG"
                     /locus_tag="U2R59_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEM8964464.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29159..31348)
                     /gene="nrdD"
                     /locus_tag="U2R59_000030"
     CDS             complement(29159..31348)
                     /gene="nrdD"
                     /locus_tag="U2R59_000030"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEM8964465.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31647..32441
                     /locus_tag="U2R59_000031"
     CDS             31647..32441
                     /locus_tag="U2R59_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964466.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32431..34473
                     /locus_tag="U2R59_000032"
     CDS             32431..34473
                     /locus_tag="U2R59_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964467.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34754..34903
                     /locus_tag="U2R59_000033"
     CDS             34754..34903
                     /locus_tag="U2R59_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEM8964468.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34914..36428
                     /gene="dltA"
                     /locus_tag="U2R59_000034"
     CDS             34914..36428
                     /gene="dltA"
                     /locus_tag="U2R59_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEM8964469.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36425..37630
                     /gene="dltB"
                     /locus_tag="U2R59_000035"
     CDS             36425..37630
                     /gene="dltB"
                     /locus_tag="U2R59_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEM8964470.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37675..37908
                     /gene="dltC"
                     /locus_tag="U2R59_000036"
     CDS             37675..37908
                     /gene="dltC"
                     /locus_tag="U2R59_000036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEM8964471.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37911..39179
                     /gene="dltD"
                     /locus_tag="U2R59_000037"
     CDS             37911..39179
                     /gene="dltD"
                     /locus_tag="U2R59_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEM8964472.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39320..40402
                     /locus_tag="U2R59_000038"
     CDS             39320..40402
                     /locus_tag="U2R59_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEM8964473.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40402..41205
                     /locus_tag="U2R59_000039"
     CDS             40402..41205
                     /locus_tag="U2R59_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEM8964474.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41275..42015
                     /locus_tag="U2R59_000040"
     CDS             41275..42015
                     /locus_tag="U2R59_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8964475.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42026..43030
                     /locus_tag="U2R59_000041"
     CDS             42026..43030
                     /locus_tag="U2R59_000041"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEM8964476.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43075..44919)
                     /locus_tag="U2R59_000042"
     CDS             complement(43075..44919)
                     /locus_tag="U2R59_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964477.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45131..45649
                     /locus_tag="U2R59_000043"
     CDS             45131..45649
                     /locus_tag="U2R59_000043"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8964478.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45777..46460
                     /locus_tag="U2R59_000044"
     CDS             45777..46460
                     /locus_tag="U2R59_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEM8964479.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46769..46842
                     /locus_tag="U2R59_000045"
     tRNA            46769..46842
                     /locus_tag="U2R59_000045"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46803..46805,aa:Arg,seq:tct)
     gene            47001..47360
                     /locus_tag="U2R59_000046"
     CDS             47001..47360
                     /locus_tag="U2R59_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HEM8964480.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47483..49114
                     /locus_tag="U2R59_000047"
     CDS             47483..49114
                     /locus_tag="U2R59_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HEM8964481.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49176..49817)
                     /locus_tag="U2R59_000048"
     CDS             complement(49176..49817)
                     /locus_tag="U2R59_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEM8964482.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50003..50079
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50099..50407
                     /gene="rplU"
                     /locus_tag="U2R59_000049"
     CDS             50099..50407
                     /gene="rplU"
                     /locus_tag="U2R59_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEM8964483.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50434..50778
                     /locus_tag="U2R59_000050"
     CDS             50434..50778
                     /locus_tag="U2R59_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEM8964484.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50791..51084
                     /gene="rpmA"
                     /locus_tag="U2R59_000051"
     CDS             50791..51084
                     /gene="rpmA"
                     /locus_tag="U2R59_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEM8964485.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51518..54325
                     /locus_tag="U2R59_000052"
     CDS             51518..54325
                     /locus_tag="U2R59_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8964486.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54516..55007
                     /locus_tag="U2R59_000053"
     CDS             54516..55007
                     /locus_tag="U2R59_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8964487.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55110..56099
                     /gene="manX"
                     /locus_tag="U2R59_000054"
     CDS             55110..56099
                     /gene="manX"
                     /locus_tag="U2R59_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEM8964488.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSIGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56132..56935
                     /locus_tag="U2R59_000055"
     CDS             56132..56935
                     /locus_tag="U2R59_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEM8964489.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56956..57870
                     /locus_tag="U2R59_000056"
     CDS             56956..57870
                     /locus_tag="U2R59_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEM8964490.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57953..58327
                     /locus_tag="U2R59_000057"
     CDS             57953..58327
                     /locus_tag="U2R59_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEM8964491.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58466..58711
                     /locus_tag="U2R59_000058"
     CDS             58466..58711
                     /locus_tag="U2R59_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8964492.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58883..59947
                     /locus_tag="U2R59_000059"
     CDS             58883..59947
                     /locus_tag="U2R59_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEM8964493.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60193..60618
                     /locus_tag="U2R59_000060"
     CDS             60193..60618
                     /locus_tag="U2R59_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8964494.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60611..61060
                     /gene="nusB"
                     /locus_tag="U2R59_000061"
     CDS             60611..61060
                     /gene="nusB"
                     /locus_tag="U2R59_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEM8964495.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61157..62011
                     /locus_tag="U2R59_000062"
     CDS             61157..62011
                     /locus_tag="U2R59_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEM8964496.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62012..63349
                     /locus_tag="U2R59_000063"
     CDS             62012..63349
                     /locus_tag="U2R59_000063"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEM8964497.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63354..63578
                     /locus_tag="U2R59_000064"
     CDS             63354..63578
                     /locus_tag="U2R59_000064"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEM8964498.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63580..64470
                     /locus_tag="U2R59_000065"
     CDS             63580..64470
                     /locus_tag="U2R59_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEM8964499.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64479..65297
                     /locus_tag="U2R59_000066"
     CDS             64479..65297
                     /locus_tag="U2R59_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEM8964500.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65404..65853
                     /locus_tag="U2R59_000067"
     CDS             65404..65853
                     /locus_tag="U2R59_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEM8964501.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65871..67553
                     /gene="recN"
                     /locus_tag="U2R59_000068"
     CDS             65871..67553
                     /gene="recN"
                     /locus_tag="U2R59_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEM8964502.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67608..67724)
                     /locus_tag="U2R59_000069"
     CDS             complement(67608..67724)
                     /locus_tag="U2R59_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEM8964503.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67797..68753)
                     /locus_tag="U2R59_000070"
     CDS             complement(67797..68753)
                     /locus_tag="U2R59_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEM8964504.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68924..69292
                     /locus_tag="U2R59_000071"
     CDS             68924..69292
                     /locus_tag="U2R59_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEM8964505.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69462..69893
                     /gene="mraZ"
                     /locus_tag="U2R59_000072"
     CDS             69462..69893
                     /gene="mraZ"
                     /locus_tag="U2R59_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HEM8964506.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69914..70873
                     /gene="rsmH"
                     /locus_tag="U2R59_000073"
     CDS             69914..70873
                     /gene="rsmH"
                     /locus_tag="U2R59_000073"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEM8964507.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70878..71279
                     /gene="ftsL"
                     /locus_tag="U2R59_000074"
     CDS             70878..71279
                     /gene="ftsL"
                     /locus_tag="U2R59_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEM8964508.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71280..73472
                     /locus_tag="U2R59_000075"
     CDS             71280..73472
                     /locus_tag="U2R59_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEM8964509.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73498..74460
                     /locus_tag="U2R59_000076"
     CDS             73498..74460
                     /locus_tag="U2R59_000076"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEM8964510.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74474..75835
                     /locus_tag="U2R59_000077"
     CDS             74474..75835
                     /locus_tag="U2R59_000077"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEM8964511.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75861..76949
                     /gene="murG"
                     /locus_tag="U2R59_000078"
     CDS             75861..76949
                     /gene="murG"
                     /locus_tag="U2R59_000078"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HEM8964512.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFSENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76964..78184
                     /locus_tag="U2R59_000079"
     CDS             76964..78184
                     /locus_tag="U2R59_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEM8964513.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78340..79665
                     /gene="ftsA"
                     /locus_tag="U2R59_000080"
     CDS             78340..79665
                     /gene="ftsA"
                     /locus_tag="U2R59_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEM8964514.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79688..80929
                     /gene="ftsZ"
                     /locus_tag="U2R59_000081"
     CDS             79688..80929
                     /gene="ftsZ"
                     /locus_tag="U2R59_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEM8964515.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80946..81623
                     /locus_tag="U2R59_000082"
     CDS             80946..81623
                     /locus_tag="U2R59_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEM8964516.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81637..82236
                     /locus_tag="U2R59_000083"
     CDS             81637..82236
                     /locus_tag="U2R59_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEM8964517.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82251..82538
                     /locus_tag="U2R59_000084"
     CDS             82251..82538
                     /locus_tag="U2R59_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEM8964518.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82571..83368
                     /locus_tag="U2R59_000085"
     CDS             82571..83368
                     /locus_tag="U2R59_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEM8964519.1"
                     /translation="MGGENFDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFL
                     DPRQSYILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYP
                     SKFASLSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVA
                     VRLEPIKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNW
                     TENTRPDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83389..84096
                     /locus_tag="U2R59_000086"
     CDS             83389..84096
                     /locus_tag="U2R59_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEM8964520.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84358..87156
                     /gene="ileS"
                     /locus_tag="U2R59_000087"
     CDS             84358..87156
                     /gene="ileS"
                     /locus_tag="U2R59_000087"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEM8964521.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMCMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87205..88731)
                     /locus_tag="U2R59_000088"
     CDS             complement(87205..88731)
                     /locus_tag="U2R59_000088"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEM8964522.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88746..89393)
                     /locus_tag="U2R59_000089"
     CDS             complement(88746..89393)
                     /locus_tag="U2R59_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEM8964523.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89577..89906)
                     /locus_tag="U2R59_000090"
     CDS             complement(89577..89906)
                     /locus_tag="U2R59_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HEM8964524.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90083..90811
                     /gene="sfsA"
                     /locus_tag="U2R59_000091"
     CDS             90083..90811
                     /gene="sfsA"
                     /locus_tag="U2R59_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HEM8964525.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90827..91840
                     /locus_tag="U2R59_000092"
     CDS             90827..91840
                     /locus_tag="U2R59_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8964526.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91840..93117
                     /locus_tag="U2R59_000093"
     CDS             91840..93117
                     /locus_tag="U2R59_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8964527.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93180..95882
                     /locus_tag="U2R59_000094"
     CDS             93180..95882
                     /locus_tag="U2R59_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8964528.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96034..96351
                     /locus_tag="U2R59_000095"
     CDS             96034..96351
                     /locus_tag="U2R59_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8964529.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96381..96701
                     /locus_tag="U2R59_000096"
     CDS             96381..96701
                     /locus_tag="U2R59_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEM8964530.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96809..98269
                     /locus_tag="U2R59_000097"
     CDS             96809..98269
                     /locus_tag="U2R59_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8964531.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98337..98558
                     /locus_tag="U2R59_000098"
     CDS             98337..98558
                     /locus_tag="U2R59_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964532.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98589..98771
                     /locus_tag="U2R59_000099"
     CDS             98589..98771
                     /locus_tag="U2R59_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HEM8964533.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98771..99184
                     /locus_tag="U2R59_000100"
     CDS             98771..99184
                     /locus_tag="U2R59_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEM8964534.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99307..100488
                     /locus_tag="U2R59_000101"
     CDS             99307..100488
                     /locus_tag="U2R59_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8964535.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100559..100723)
                     /locus_tag="U2R59_000102"
     CDS             complement(100559..100723)
                     /locus_tag="U2R59_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964536.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100877..100950
                     /locus_tag="U2R59_000103"
     tRNA            100877..100950
                     /locus_tag="U2R59_000103"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100911..100913,aa:Arg,seq:cct)
     gene            complement(101019..102158)
                     /locus_tag="U2R59_000104"
     CDS             complement(101019..102158)
                     /locus_tag="U2R59_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8964537.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(102272..102856)
                     /locus_tag="U2R59_000105"
     CDS             complement(102272..102856)
                     /locus_tag="U2R59_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HEM8964538.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(102939..103361)
                     /locus_tag="U2R59_000106"
     CDS             complement(102939..103361)
                     /locus_tag="U2R59_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8964539.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADKIAIMILLNIFIENELTDE
                     SQFKLENFMEFYAINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(103379..103699)
                     /locus_tag="U2R59_000107"
     CDS             complement(103379..103699)
                     /locus_tag="U2R59_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8964540.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            103999..104139
                     /locus_tag="U2R59_000108"
     CDS             103999..104139
                     /locus_tag="U2R59_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964541.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            104437..104694
                     /locus_tag="U2R59_000109"
     CDS             104437..104694
                     /locus_tag="U2R59_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HEM8964542.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(104665..104973)
                     /locus_tag="U2R59_000110"
     CDS             complement(104665..104973)
                     /locus_tag="U2R59_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964543.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            105051..105797
                     /locus_tag="U2R59_000111"
     CDS             105051..105797
                     /locus_tag="U2R59_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HEM8964544.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            105812..106015
                     /locus_tag="U2R59_000112"
     CDS             105812..106015
                     /locus_tag="U2R59_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964545.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106031..106369
                     /locus_tag="U2R59_000113"
     CDS             106031..106369
                     /locus_tag="U2R59_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HEM8964546.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            106356..106526
                     /locus_tag="U2R59_000114"
     CDS             106356..106526
                     /locus_tag="U2R59_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964547.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(106624..107289)
                     /locus_tag="U2R59_000115"
     CDS             complement(106624..107289)
                     /locus_tag="U2R59_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964548.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            107344..108042
                     /locus_tag="U2R59_000116"
     CDS             107344..108042
                     /locus_tag="U2R59_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEM8964549.1"
                     /translation="MQELVILKNKEAVTTSLQVADSFEKEHKNVLRDIEKLKEDVLNF
                     EQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            108220..108561
                     /locus_tag="U2R59_000117"
     CDS             108220..108561
                     /locus_tag="U2R59_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964550.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            108554..109225
                     /locus_tag="U2R59_000118"
     CDS             108554..109225
                     /locus_tag="U2R59_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEM8964551.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVTPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109231..109917
                     /locus_tag="U2R59_000119"
     CDS             109231..109917
                     /locus_tag="U2R59_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964552.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIERLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            109920..>110366
                     /locus_tag="U2R59_000120"
     CDS             109920..>110366
                     /locus_tag="U2R59_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964553.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEY"
BASE COUNT        36296 a        18804 c        23089 g        32177 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacgag aaactaacgg aaaaatagtt
     2041 cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttag
     2101 tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa gcaaaaacag
     2161 cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt tgaacaccgt
     2221 ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat tttgtgaaaa
     2281 tggctttcta catttttgca taaatttggc ttaataccga gaaactggct tttgaatacc
     2341 gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
     2401 acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc aggagaacac
     2461 cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt ttacttatgt
     2521 gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag gtcatctttg
     2581 aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat atgccaaaaa
     2641 tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg aaagaaaaag
     2701 attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt agttctttgt
     2761 taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta tttcacttaa
     2821 aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg tttatatcaa
     2881 gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa taatttctca
     2941 aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta cttgactttc
     3001 ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga agtttacaga
     3061 aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc tgagactttt
     3121 cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt ttgtgaccgg
     3181 cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac gcttattgaa
     3241 aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg tggatccggg
     3301 gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg ctgaaacaga
     3361 tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat actccaacgt
     3421 gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg aatacttggg
     3481 agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa tcatgcgagc
     3541 agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag taggggatat
     3601 agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg gtacagataa
     3661 tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag aaatgaaaac
     3721 taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac cgaatatttt
     3781 ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg cacaattttg
     3841 tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt actccatccc
     3901 attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa aactagatac
     3961 accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga acttgaagaa
     4021 aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat atatctcagt
     4081 agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga tcgattggat
     4141 caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg cagatggaat
     4201 cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag cgattcgtta
     4261 tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga tggcttgtgt
     4321 cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa cgaatccaga
     4381 tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga atttgggtgg
     4441 aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga cggctgaagc
     4501 atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt tcaataacaa
     4561 atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac cagataaccg
     4621 tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc aattccaccc
     4681 agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg tcggagcatc
     4741 attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa agtagcaaga
     4801 gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta ttatttgtag
     4861 gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat attttatttt
     4921 ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa ctaccgaaat
     4981 gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt ttacaaaact
     5041 taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag ctgctcgtaa
     5101 aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc aagcaatcct
     5161 tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg gtgcagctaa
     5221 atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg aagcaatgaa
     5281 catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg ctttggaatg
     5341 tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat ttgaagaaaa
     5401 cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct cagttgaatg
     5461 tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg aattagctga
     5521 tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt gcggtatcgg
     5581 taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc acttacaagc
     5641 aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat caggtattcc
     5701 tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg ttaacactga
     5761 attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta aagataaaga
     5821 aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa tcgttgaaga
     5881 tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat ccacataaca
     5941 gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct tttttactta
     6001 aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag catatccatg
     6061 aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa aggaaaccga
     6121 cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc attgattcca
     6181 gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat acaagatgtt
     6241 cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc caacaacata
     6301 ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa aatcaatagt
     6361 ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga agcggtagta
     6421 ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt caaaggattt
     6481 gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg gacagaaaat
     6541 aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc aacgatcaat
     6601 gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc tgcacgagaa
     6661 ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt tcgaggagcg
     6721 ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg gcatttcatg
     6781 attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt aggaaatggt
     6841 atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa attgcaggaa
     6901 attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc gaaagaatta
     6961 aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct gcagcagcca
     7021 cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac gatctatgcg
     7081 aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac cgtggaagga
     7141 aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt ggcttctgat
     7201 cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac aacgacgatt
     7261 tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact aacagcctta
     7321 ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat ttgacaatgg
     7381 cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa tttaaaattc
     7441 cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt gcacaagcag
     7501 agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa gatggttacg
     7561 gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt tctgcctcac
     7621 aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc cgtccaccta
     7681 aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga aaagatccgg
     7741 aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg caaagacagc
     7801 ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc ttttctccaa
     7861 tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa acttctgtat
     7921 taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta atcgttctac
     7981 tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa ggcgacgtgg
     8041 tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa ttagtattgg
     8101 aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg gatagtatta
     8161 ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca ttgagtggcg
     8221 ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca agaaacatcg
     8281 aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga agccgtatgg
     8341 atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa ctttcacgtg
     8401 aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt acccgaaaag
     8461 aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga aaaaatatga
     8521 ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa acaaaaaaca
     8581 atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat ccgaccagaa
     8641 atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg ttgtaaatcg
     8701 acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa tcatgaaaga
     8761 aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg gtttcaaatt
     8821 cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg gtaatacata
     8881 cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg gacgtcaaaa
     8941 attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc tcaaagacgc
     9001 aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta tctgataggg
     9061 atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct gaaaaagtcg
     9121 taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta tccacttgat
     9181 aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa accatttacc
     9241 taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta tagacttgcg
     9301 attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga tgggtctttt
     9361 tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg acctcagttc
     9421 caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg atcaattgat
     9481 cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat tatttgagcg
     9541 aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag tcgttaaggc
     9601 actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg ggattcccca
     9661 tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag ccaaattaac
     9721 ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg tagttcctga
     9781 aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat tgatgaatgc
     9841 agattttaga aagggaataa aagaagccac tacgccagca gatatcatca gacagattag
     9901 tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa aaggaggaaa
     9961 ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca tacttatatg
    10021 tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa attcgaaaca
    10081 caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc agatgcaatc
    10141 attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa agtaaagcgt
    10201 gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc attgagagat
    10261 attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa aaagccgaca
    10321 atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat cgcaggcgga
    10381 atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa ctcagcagac
    10441 tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt tgccatgatg
    10501 gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg ttttgcccca
    10561 ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg cggaatgatt
    10621 ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag cgtaaaaaaa
    10681 gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt aattattggg
    10741 cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc tttgacaaat
    10801 tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat cgggatcatg
    10861 atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc gatcggtttg
    10921 atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat gacacctccc
    10981 ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga agaacggact
    11041 tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc tataccgttt
    11101 gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc agtcgctgca
    11161 gggatttcca tggcagtagg agttacttca atggcacctc atggagggat ttgggtgatg
    11221 ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc atcaggtaca
    11281 gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa aaaacaagac
    11341 aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta tatacaatga
    11401 aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc aatatttgca
    11461 gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca ccagtaatct
    11521 tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg gcagtaagag
    11581 cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc ggtacgatag
    11641 aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat gcgtctttga
    11701 aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct catgcggtaa
    11761 atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct gaaggaggtg
    11821 ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa gaaacaggaa
    11881 tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa aacagaactc
    11941 caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt ccatttgttt
    12001 tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa tacggagttg
    12061 ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg agagaaatat
    12121 tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct aataaaaagg
    12181 tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag gctagtttat
    12241 actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat accctcttaa
    12301 ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc tcgaagccaa
    12361 tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg gtgattttat
    12421 gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa acaaccaatt
    12481 tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga ttaaacgtga
    12541 ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg ccatgcttat
    12601 tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag aagaagaaac
    12661 agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata tggtcttatt
    12721 cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat ttgatggttt
    12781 gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata caacggcaaa
    12841 agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg gttcaaaagc
    12901 ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc gcgggctaga
    12961 tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa aagcttttag
    13021 aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac ataaattcat
    13081 gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag aactgacaaa
    13141 agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat aaattattac
    13201 gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc tcgcttctct
    13261 cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt ttttatccag
    13321 gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc aatcatgatc
    13381 tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat ggattcaacg
    13441 attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt gatcttacgt
    13501 aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt tatcttgtgg
    13561 ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt gattcctgct
    13621 ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca aggcatcgta
    13681 ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga taaatgaaag
    13741 ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta ctcaaaaaac
    13801 cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag atcaaatttc
    13861 atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc ggccattaac
    13921 aagatagagt gctgtacata tcaatggaat gactccggca atcacataca atcctctaaa
    13981 tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc ctaggtctaa
    14041 accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga tttttaaaca
    14101 aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg ctccagagat
    14161 aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg ttaagaataa
    14221 atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc cagtcaatgg
    14281 acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag cagcaactaa
    14341 gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag aaagacccat
    14401 caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat tgatattcca
    14461 tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag gaaagacaag
    14521 gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga aacgaaaatc
    14581 agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta aactagtact
    14641 taatccataa taattgatgc cttccccttt tttagatgca gggatatatg cagtaacgat
    14701 agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc gaactaaata
    14761 caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat agaagatcgc
    14821 gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca tgaataagcg
    14881 tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc tcaagctggc
    14941 gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat aaatcaggta
    15001 gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt tcttttccat
    15061 gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt gaacttctac
    15121 atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat ctcttgtaga
    15181 cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca ctgctttgat
    15241 caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt tcatatcaaa
    15301 tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt aattcatgtt
    15361 ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa aaaaggaaaa
    15421 aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta gtaaaatacc
    15481 tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag tttggatggg
    15541 ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga ttttccgatt
    15601 atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc ccatacgtat
    15661 atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag agaatttaac
    15721 cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata ttcacaattc
    15781 atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta tcgaatcaat
    15841 cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta tgtaaaagag
    15901 tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct attaaacgga
    15961 aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg tgtgcggaca
    16021 gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa attttgtggc
    16081 atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga tggtattatc
    16141 accgttaaag accatcatat cgttattttg aatatggact tgttagaaga caatattatc
    16201 ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaac
    16261 ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg
    16321 aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggaacaatt
    16381 tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg agttggtagg
    16441 agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa taagaagagc
    16501 caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt agatgtaagc
    16561 ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt cacagccctt
    16621 tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc caaaagtccc
    16681 gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg ggcttttggg
    16741 gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag ttaatttgat
    16801 actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat aacgcgaaac
    16861 agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa tgatgatttc
    16921 tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta cacgataatg
    16981 tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag cttttgcagc
    17041 attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg aatcgattct
    17101 gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt cacgctgtcc
    17161 catatctaat agcaatactg agccattttg atcatttccg actgcgtctc ttaagtaatt
    17221 atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca agactcgtcc
    17281 tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt gatctgttgt
    17341 gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca ccggccagcc
    17401 aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa gtaacctccg
    17461 atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc caattttttc
    17521 tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc gtagtagtag
    17581 acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag taatacgtaa
    17641 ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt tgtatatcca
    17701 tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg aatctgtgat
    17761 ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa atactggctt
    17821 ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat cttttgttgc
    17881 gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc tgctcttgaa
    17941 acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat gcggataact
    18001 gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata agggaaatac
    18061 acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac aaaccatttt
    18121 ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc aaaaggaagt
    18181 actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg attatggcag
    18241 tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc acagttggga
    18301 caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt atctgaaaaa
    18361 ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag ctgttcttgg
    18421 gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc gccagccata
    18481 cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata gatattcagg
    18541 cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc gccgcaatta
    18601 ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa ttaattaacg
    18661 gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc gttggaaaga
    18721 tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac gttttctaca
    18781 ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc gcaaactgga
    18841 catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc tgcttgttgt
    18901 ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt tgcattcatt
    18961 cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc ggctgcttcc
    19021 ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc acctagcatc
    19081 gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga aatgctggct
    19141 acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc caatgcagta
    19201 tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg ttgaccatct
    19261 gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa atactgctca
    19321 ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt ataaaataaa
    19381 atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa ttctgcgtta
    19441 tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc ctttatttct
    19501 tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa tttgaatcgg
    19561 tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg agctgcgtca
    19621 tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc accatcgacc
    19681 aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa aacatcttct
    19741 gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc ttttgtcatg
    19801 accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc tgccagaccg
    19861 ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc ctctgattca
    19921 gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga aacttctcgg
    19981 actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa aaagccgaga
    20041 aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat tttttaaaaa
    20101 agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca gcgtttcgaa
    20161 gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt ttcccacaaa
    20221 acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag tgcagcaaag
    20281 attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg caacgaatgc
    20341 gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat cgatgctgcc
    20401 agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta tgcgcctaca
    20461 aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac aggagctttc
    20521 aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat cttagcaacg
    20581 accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt tgattttaaa
    20641 cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga atcgactatc
    20701 agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg gatgcgggat
    20761 gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac tttagatgat
    20821 gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt gagtgcttgc
    20881 gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc agccggcaaa
    20941 gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct gatgtatcag
    21001 caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt tacagaattg
    21061 gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag cgatactcaa
    21121 aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac agtcaaactt
    21181 gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga tgatcagata
    21241 gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga actacgcagt
    21301 aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca taaaaaacag
    21361 acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga agcgacaaga
    21421 cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct atctgtcact
    21481 cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg actagtgatt
    21541 gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt gcagctttcg
    21601 gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt ttatattaca
    21661 agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga agagggaaca
    21721 gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc tcaagaacaa
    21781 gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc cgaagctgtt
    21841 acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa tgggcaatat
    21901 gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag cacaagagct
    21961 gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag cggtttttac
    22021 aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc ctgatgatat
    22081 cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac aaattgatgt
    22141 ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt agttttaaac
    22201 tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg acagctacat
    22261 gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata cgatcgatat
    22321 gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac gcgatttgca
    22381 tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat gtagaaatcc
    22441 ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa tggcaatgga
    22501 aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat caccgatgga
    22561 agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc atgatgcaga
    22621 tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa cagctatgta
    22681 tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac atggtctgtc
    22741 tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg tcgaaggaag
    22801 acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa gcagcacaag
    22861 agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg atggtgcagg
    22921 aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa aaacagaaat
    22981 cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag cagtgatcct
    23041 tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg cagcagcaag
    23101 aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa tcgttttatg
    23161 cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca tcggcgttac
    23221 cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt ttacccttta
    23281 tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac aaaatcaaat
    23341 cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg cttacttaaa
    23401 gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa gctttgaaga
    23461 agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt ttgaaaacta
    23521 ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga cagcaaccgt
    23581 ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc gacaggcggc
    23641 ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg tgtagaagaa
    23701 gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc tacacctgtt
    23761 acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga agtaggcggt
    23821 gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga gctgagctat
    23881 gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc ttcaacggag
    23941 ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag gaacaggaaa
    24001 acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga aagacaatct
    24061 gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc cagatgtttt
    24121 ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt tgcagacgga
    24181 attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag aagctgaaaa
    24241 aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc ctggagattt
    24301 tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc aatctcgttg
    24361 tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat tgcaagaaga
    24421 gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt taggaaaagc
    24481 agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt atcaatggtt
    24541 cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa aattggtaaa
    24601 atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt tttattatca
    24661 ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac agataaacca
    24721 gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca gttttcaggc
    24781 tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg atgatgatca
    24841 aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg tcatatctat
    24901 tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt cgaatctcag
    24961 caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc caatgacctt
    25021 cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga aaaagacaaa
    25081 aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt gcagttgcgt
    25141 gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa attgattttt
    25201 tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct ggccgctgta
    25261 tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa gataataggc
    25321 ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga tttcgtgcct
    25381 gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa aatttccggt
    25441 ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga gacagcgaaa
    25501 aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg gaaagtcgta
    25561 gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga aaatcctgtc
    25621 gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa tggataagag
    25681 atcattatac gacggattga atcaattaga atcagagttg agaaatacat taacagaact
    25741 tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt tggagatgga
    25801 aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag ctccagctga
    25861 aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt atgaagaagg
    25921 attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc cttgtgcgtt
    25981 ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag gagactggag
    26041 cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta taatcaaaaa
    26101 agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc aattggaaat
    26161 ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct tatcgcaagt
    26221 gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac accccaaaaa
    26281 agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt gttaaaagaa
    26341 ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga tcctggacat
    26401 gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc aggacctaca
    26461 gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt attttatggc
    26521 ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa agaacagaca
    26581 gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac gaatttctta
    26641 gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt ccatgaagaa
    26701 taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc agtaaagggt
    26761 gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga agttgatgaa
    26821 gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga aaaaccaaat
    26881 gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt ctaccgtcag
    26941 taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa tgaggaaatc
    27001 agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa tgaataagag
    27061 gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa aatcattcat
    27121 attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga gtttcgcgga
    27181 catccattag taattgccag acaccccagt gacactggtg ggcgtggagt agtgactaca
    27241 gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca aaaagcgtat
    27301 gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag cgatatttcc
    27361 aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt tagtatcgat
    27421 gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat caaaatcgcc
    27481 cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc gggagtaagt
    27541 tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg aatcacggta
    27601 gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa atttcatggg
    27661 gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg aaaagaccta
    27721 tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta ttctctttat
    27781 cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg aaaatctgtg
    27841 ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct gactcagttg
    27901 cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca tgggaaaaca
    27961 gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt gacattgcca
    28021 gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg ggaggaaatc
    28081 ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct ggacccgatg
    28141 acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa acagctttga
    28201 gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa gtcttgcttt
    28261 ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac aacttgattg
    28321 gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg aaattgtagt
    28381 tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat ttgcgaaagg
    28441 agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc tgtccatgac
    28501 cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg cagacaaaca
    28561 tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta atcgttgcgc
    28621 aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata tcggaaattt
    28681 tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac gtaaagactg
    28741 ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat atagttttgg
    28801 ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa acttctttca
    28861 tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat aaataagaac
    28921 aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga gggcgttcaa
    28981 agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct cttattctga
    29041 ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg aaaaatatga
    29101 ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt tcacaacctc
    29161 atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc atcggacgag
    29221 cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt tttggatcat
    29281 gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca ccttcgaaac
    29341 cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt ttgtcatatg
    29401 caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg tattcacagt
    29461 agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc aatttttcaa
    29521 atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat tctttatctg
    29581 tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg tcagttagac
    29641 tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc catgcatctg
    29701 cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct gggtttgttt
    29761 cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag cctaacgata
    29821 cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa agacgtttcc
    29881 cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct ttacaacgtt
    29941 ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt aactgccaga
    30001 atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat gtaacaacac
    30061 ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac ccttgcaaga
    30121 atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt ttatcgtaat
    30181 tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt ttgatgtcgt
    30241 aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc agtttaggga
    30301 agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa attgcttttt
    30361 gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg aaaggagttt
    30421 gtccatttga agtaaataag gtattgattt catattccaa actttgcata gcatcgaaga
    30481 tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa tcgatccatt
    30541 cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca agcaattcat
    30601 ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca ataatctgtg
    30661 agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca ttgccgattt
    30721 tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc atcggtgtat
    30781 aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca tttgctatat
    30841 gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc agatctcgct
    30901 gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt tggtccttgt
    30961 tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca aaatctcgtt
    31021 tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct agtaatatat
    31081 gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg cttttgattt
    31141 cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt gataatgagc
    31201 cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca tcgaaatcaa
    31261 catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc tgagtaacga
    31321 cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt gttcttgtct
    31381 atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag tattcaatgt
    31441 gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa aaaaggtgaa
    31501 aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa aataattgaa
    31561 taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa ttattcgtag
    31621 atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa gaattggaaa
    31681 agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct cccgtcaaag
    31741 ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt atgggcccaa
    31801 gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg cctacgatgg
    31861 gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag ctcagtgact
    31921 ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat accctaaatg
    31981 caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag gaaatggaaa
    32041 agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa cggtatcccg
    32101 atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt gttgttcagc
    32161 cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg gctacagaat
    32221 tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg ttagtcaccc
    32281 atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat ggtgtgattt
    32341 tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta atagacatgc
    32401 aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt taaaagtttt
    32461 tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc cgtaatgatc
    32521 tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc aagtcaagat
    32581 acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt tttgcttttt
    32641 ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat aggcatctat
    32701 cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga aatcatgata
    32761 attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc caaactcttt
    32821 tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt tatctccatt
    32881 ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt atctgtatat
    32941 tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa agaacaagca
    33001 gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat cgggttacta
    33061 cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc atggatgatc
    33121 agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt tttcgtttgt
    33181 gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat catattgagt
    33241 aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac gcaagttcat
    33301 ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat ttctttaatg
    33361 acaattggcg gcacggctag tatctctact attttatcct accaggagaa agtttcctcc
    33421 ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat tctagcagag
    33481 gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg gagtatctat
    33541 agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga aacacaatat
    33601 caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc acctggtcat
    33661 actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata tggatctagt
    33721 attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag tgtattaggt
    33781 gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt ttttgaaaaa
    33841 gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa taatgaaaaa
    33901 atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt ttattattct
    33961 tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact tccggatgac
    34021 caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc ttccagctat
    34081 tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac actatttgtc
    34141 gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt agcagaagca
    34201 gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca aagaaggatc
    34261 agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat attagggatc
    34321 actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc cgattactgg
    34381 ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta tgtcattacg
    34441 agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa gataataaat
    34501 agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga tttttgtcac
    34561 aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa aaagcagtga
    34621 tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa aacggtttct
    34681 gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg aggttatatg
    34741 aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt ggggaaaatt
    34801 catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc tgtatcacta
    34861 taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag agtatggaaa
    34921 tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat cgagttgctt
    34981 atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac gcacttgctt
    35041 attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc aatttggagt
    35101 ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat ttgccgattg
    35161 aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa ccatctatgg
    35221 tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata acaaaaaaag
    35281 aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc gtaaaaggta
    35341 cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa ggcgtacaaa
    35401 tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt gggatcaagc
    35461 ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta ttttctattt
    35521 atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt gttcaagact
    35581 ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt tctactccat
    35641 catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg ccggaattgg
    35701 acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt ctacttgatc
    35761 gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact gtagctattt
    35821 caagtattca gattgaccag catgtactag atagttatga ccgactaccg attggctacg
    35881 taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca aaaggagaaa
    35941 cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac aatcccgaaa
    36001 agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca ggggatgcag
    36061 gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag caggtcaaat
    36121 tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa gacaaccgaa
    36181 tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag ctggttgctt
    36241 ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa tctatcaaag
    36301 aacaattact agaagttgta atggattata tgattcctca gaagttccat tatgtcgatc
    36361 tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct gaggtgaatc
    36421 ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt ttcttttagc
    36481 cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat taccagttta
    36541 tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt attggcaaca
    36601 gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg gctattttgt
    36661 ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt tagcgataat
    36721 tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat cgttacttgg
    36781 ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg aaataagaga
    36841 tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt tctttccaac
    36901 aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc tccatccgcc
    36961 tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt ttgtcggttt
    37021 tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg tagtgggacg
    37081 cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt acgtgtacag
    37141 tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta caagctacat
    37201 gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga atatcaaaga
    37261 attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg tatatatgcg
    37321 attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa tgtcaaatat
    37381 cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt ggtactacat
    37441 cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga tccgatttaa
    37501 gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag ccgtattttt
    37561 gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag ataaactttt
    37621 ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag gaaaatggaa
    37681 gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag aaaaaatcgt
    37741 gatattgatc tatttgatga agggttgctt gattctttag catctgttca attattagtc
    37801 gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg agaggattgg
    37861 tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt atgaaaaaga
    37921 aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt gtgtttttta
    37981 cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc tcttcttcca
    38041 tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct gaaaaacaat
    38101 atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat ccgtctgttc
    38161 tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc gggacacaat
    38221 cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac aagaaagtcg
    38281 tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat tactttaata
    38341 cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa gtaacgcctg
    38401 ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag aatgatacgt
    38461 tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa tctttgaatc
    38521 agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc aatattgggt
    38581 tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa caataccaag
    38641 aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg aataatccat
    38701 tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca gagctcaaac
    38761 agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt cagctggtct
    38821 tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg gttaacgaga
    38881 aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc aaaaagatca
    38941 aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat caagcgggta
    39001 ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg gctgcagatc
    39061 aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat catcttgacg
    39121 atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa ttaaaataaa
    39181 gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg aataaaagat
    39241 aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac aatatgaata
    39301 tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg atttaacttc
    39361 tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag aatatgccaa
    39421 accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca aacatggtgc
    39481 tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt ttatggtaac
    39541 aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt gggggcaagt
    39601 catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc acggtgtgat
    39661 tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt atgaaataaa
    39721 ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt ggggcatacg
    39781 tcctggagat atggtcactc catatattga atacaaacga atgaatggca gtaaatattt
    39841 actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag tattagagaa
    39901 tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc aagaagaagt
    39961 aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg cttttgcttt
    40021 agatactggt acagcaggag acactccagg aatgacacca aaagaagcag attcgatttt
    40081 aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata aaaaattatt
    40141 gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata cagtgatttc
    40201 tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc cgtctgtagc
    40261 cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg aagatgatta
    40321 tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg aaacagttga
    40381 aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata tcggaaaaaa
    40441 gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt cttatctata
    40501 atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc ggaagaaagc
    40561 atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc attcaactat
    40621 gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag taacctttta
    40681 ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt gatcaattca
    40741 gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat cagcggagtg
    40801 agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt catgccagaa
    40861 gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt ttcagcactc
    40921 atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt cgactatcct
    40981 gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga tagaattggt
    41041 acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc aatcgctttg
    41101 ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga attttatgaa
    41161 caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt aagcagttta
    41221 ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg tacgatgaaa
    41281 ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac aacaggttat
    41341 ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac gctgatcaaa
    41401 ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca ttatcatcat
    41461 gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc taagagaaat
    41521 ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt tgaagaattg
    41581 acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt aaaaattggt
    41641 ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc catgcgtatc
    41701 gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta tttggaaagt
    41761 ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct ttttgaagga
    41821 aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc gaaatcagct
    41881 aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga acaattgaaa
    41941 aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc agttgacaaa
    42001 gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc acgacccaag
    42061 aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg aacctatttt
    42121 gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata cgcttgaaga
    42181 aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct taagtggagg
    42241 cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc ctgatgatgg
    42301 ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac ttcatgaatt
    42361 gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg gcatgaaatt
    42421 ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa caattatgtt
    42481 cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca aaatcgaatc
    42541 aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc ttccagaaga
    42601 aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa ttttcggcgt
    42661 agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga aaaaaatcaa
    42721 tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt ctccagattt
    42781 caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt tgaatgtctc
    42841 agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag gagatatctc
    42901 tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat caaaaatagt
    42961 cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat tgcttacctt
    43021 actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta ttttttatac
    43081 aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag tatctttttc
    43141 ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta agtcaaaacg
    43201 ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat cgtaatgtgc
    43261 actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca aataaatttt
    43321 tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta aagcgtggat
    43381 caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat ctgcttggaa
    43441 ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga taagatttgt
    43501 cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt ctaatatctt
    43561 ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca gattctccat
    43621 ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc gaagctgctc
    43681 ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc tccgatcttt
    43741 gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta gaatgataat
    43801 atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg tttggatgta
    43861 aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta cataaaaacg
    43921 gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc ttataacact
    43981 agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag ttgcataaag
    44041 cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc attttttata
    44101 gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga taataaataa
    44161 atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa tatcttctga
    44221 tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg agtattcaag
    44281 acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag cgataaaaac
    44341 agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac taatcaatgg
    44401 tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat aaggagatga
    44461 gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca cagccaatga
    44521 gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct tttcgcctag
    44581 atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt ccaacggttt
    44641 ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa tcgtacgagt
    44701 gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc acgaatcttt
    44761 tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga aataagcaat
    44821 tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac gtaaataaaa
    44881 agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc tttctaaaac
    44941 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
    45001 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
    45061 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
    45121 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
    45181 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
    45241 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
    45301 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
    45361 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
    45421 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
    45481 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
    45541 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
    45601 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
    45661 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
    45721 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
    45781 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
    45841 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
    45901 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
    45961 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
    46021 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
    46081 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
    46141 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
    46201 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
    46261 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
    46321 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
    46381 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
    46441 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
    46501 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
    46561 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
    46621 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
    46681 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
    46741 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
    46801 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
    46861 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
    46921 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
    46981 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
    47041 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
    47101 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
    47161 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
    47221 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
    47281 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
    47341 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
    47401 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
    47461 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
    47521 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
    47581 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
    47641 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
    47701 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
    47761 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
    47821 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
    47881 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
    47941 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
    48001 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
    48061 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
    48121 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
    48181 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
    48241 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
    48301 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
    48361 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
    48421 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
    48481 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
    48541 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
    48601 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
    48661 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
    48721 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
    48781 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
    48841 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
    48901 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
    48961 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
    49021 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
    49081 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
    49141 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
    49201 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
    49261 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
    49321 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
    49381 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
    49441 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
    49501 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
    49561 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
    49621 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
    49681 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
    49741 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
    49801 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
    49861 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
    49921 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
    49981 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
    50041 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
    50101 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
    50161 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
    50221 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
    50281 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
    50341 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
    50401 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
    50461 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
    50521 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
    50581 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
    50641 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
    50701 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
    50761 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
    50821 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
    50881 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
    50941 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
    51001 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
    51061 tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt gacaagactt
    51121 ttgtcacagc cttttttgtt tataaaaata aaagttgtag tggaggctac gaagtttact
    51181 ttgtcttttt acacttaata tttttttgcc aatttggaat caggatgttt tgataactat
    51241 cgttttcaat tgatggaagc tatattgttt gctatcagtg aaataattat atggtaaaca
    51301 gtgttctttt tcttgtttcc attataaaaa tcgtatcggg atttttcgtt cttttaaatt
    51361 gaacatttct atctatccgc gtgttatcaa caaaacaaaa tcaggtaaat agttgacgaa
    51421 acagaaataa atacatagta ttatgttttg aagcctaagt acaatagtct atagaaaagg
    51481 agcgatacca ttggcaaaac gcattgaccg aatttatatg tatgtcaaag aaaaaaccgc
    51541 tcatttaaca aaggcagaat atgatcaagg agtaacaaca caggaaattg ctgaagtgtt
    51601 agggattcag cgaacaaata gcagtaaaga tctgaatcag ctagtgcgcg aaggaaaact
    51661 gataaagaca gacggacgac cagtacgtta catatatcaa acactcgtta cgcacgtaaa
    51721 gccagttaca aaacatgtag tcagttacaa agaaacgccg gtctctgaag aaaaaaatac
    51781 actccaaata gatactaagg atatctttgc aaaaatcatt ggagctaacg gcagcatgaa
    51841 aaattcagtg gaacaggcaa aagctgcgat tttgtatccg ccaagaggat taaattgttt
    51901 gattacagga cctaccggat caggaaagac ttattttgca cacgcgatgt atcattttgc
    51961 aaaagcgcat catgtaatag atgaggaaac ggaactgatt gttttcaatt gtgctgatta
    52021 tgccaataac cctgagcttt tgatgagtca tttatttggg tacgcaaaag gtgcttttac
    52081 aggcgcagat gaagaaaaaa tggggattat cgatcaagcg gatggcggta tgctgttttt
    52141 ggatgagatt caccggttgc cgcctgaagg tcaagaaatg atcttttact ttatggatca
    52201 tggaacttac agtcgtcttg gggaaacaac gaaatcccat gaagcaaatg tacggatcgt
    52261 aggtgcgacc acagaagacc caggttcttc tctattagaa acttttgttc ggcgtatccc
    52321 aatcaatatc aaacttccgg cttttgaaaa acgtcctgca aatgagaaag tcgatttagt
    52381 aaaaatcatg attgcccacg aagcaaaccg cacgcagcga aagatttctt tgacagaaga
    52441 tgtagcaaaa gcattgatcg gcagtgtgac ctatggaaat ataggacaat tgaagtcaaa
    52501 tatccagtta gtatgtgcac gaggatttct aaatcatatg caatcacccg aaatctcgat
    52561 cacaatcgat gatttgacag aagggattcg tagcggattg attcaattag caagcaaccg
    52621 cagtgcaatg gcagagcttt ctaaaatatt ggagccaaag ataactgtag caccaaatga
    52681 tacgatcatg aaaatccaat cggactccta tgagttacct tataatctat atgatatcat
    52741 cggagataaa gcagctttac tgaagtcgga tggtttggat caagaagcaa tcaatcattt
    52801 catttctaca gatatcaaca tccatctgaa gtctttctat aaagaccatg gtttttcttt
    52861 taatgcagac agcaaattag cagaatttgt agatccgaaa atcatagaag tgaccaatca
    52921 gatttatgta atggtcaaaa gatctttacc atatgagttt cagcaaaact ttatttatgc
    52981 tatgagcttg catatcagtt cttttttgaa aaaaatcaac ttaggagaag aacggcatac
    53041 gaatgataac atccgtgaga tggcttttga ttttccagat gaatatgctg ttgcgaaaga
    53101 agtgcgtagt tatatcgaaa cgtattttca agtggagatt ccagaaagtg aagactatta
    53161 cttgaccgtt ctactcgtct cgttacgggc aaatcaagca agcggcagaa tcggtgtagt
    53221 cgttgcagct cacggaaaca gcacagcaag cagtatggtc caagttgtcc aacagttgtt
    53281 agatgcagag aacgtacgag cagtagacat gcctttggat atggatccga aaacagcatt
    53341 ggaccgaatt gaacgcaatg tacaagaagt agatgaagga agcggggtca tactcttagt
    53401 agatatgggg tcccttgcgt cgtttaattc gcaaattcaa agagacactg gaattccagt
    53461 acgtactgtt gatatggtaa caacttctct agttttggaa actgtacgaa aggtctcagt
    53521 attagggaca gatctagata tgttgcatga atcattgaaa aattttcgag gttacgcaga
    53581 aatatcttct gtagaatctg ttcaggaagc aaaacctatt cataagaaaa aagctgtttt
    53641 ggctatctgc gcatctggcg aaggtacagc acaaagaatc aaagaattga tcgaacgagc
    53701 ggtaaacaag cgtcaagaaa cagaattaga agttctagct ttgtcgattg tggaagtgaa
    53761 agaagaactg ccagttatcc aaaaagaata tcagatcata gctactactg ggattactga
    53821 tttgaatatc caagccccat ttattccttt agaacgtttt attgatcaaa atatcgaagt
    53881 cattttggat cagttgctga tggaatcaga attggaggaa actgaattca tctccctaga
    53941 tgaagagtca gctaaaaata cgtgtgttga gtttatctct gataacttca tctttattaa
    54001 tggtagtaag ttaatcgatc caatgtggca attttctaca caaatctctc agacgacggg
    54061 aatcggcgat gaagaatatg gattcaaaat caacctagtg atgcacacag caggaatgat
    54121 cgaacgtatt attcggaatg aaccattgac tgtggaagaa aacgaattga caaatacaac
    54181 gaatgatcct ctttatagcc aattggcagc ctcagttgtt ctgttggaag atcagataaa
    54241 agtaaaagtg ccgatagaag aaatgtatta tctgctacgt ctagtccata atcagttaga
    54301 taaaaaagaa tacactgtgc catgaataca caaaaacgat acacttttat agtgtatcgt
    54361 ttttgtgtat tggttaagaa tcctttaaat tcaattagtg tatcgtaaaa aagttggcac
    54421 gctttttgct tatagtagtg tgtgctagga ggtggttgtt cacacagaaa tgataggggt
    54481 ttctgtgaag tagtgaggaa gaaggagttt tgcagatgga tattcgattg gcacgtatag
    54541 atgatcgttt aatccacggg caagtcgcaa cagtttggtc gaagcaaaca ggtgttgaac
    54601 gtatcattgt gatcagcgat gtagtcgctc aagataaatt gagaaagttt ctactaaaag
    54661 aagctgcacc gccggggatc acagcaaatg taataaccgt gcagaaaatg attcaaatct
    54721 atcatagtgg attattatca cgagcaaaag tgatgctttt attcaccaat ccccaagatg
    54781 ttgaagcggt tgtccgctgc ggtgtacagt tgaagtcgtt gaatatcggc ggtatgagtt
    54841 ttactgaagg caaatcaatg attaccaatt ttgtttcagt aaatcaacaa gatattgatt
    54901 cctttcgtta cttgaacagt caagaagtgg agttagagat tcgaaaagta cctgctgaca
    54961 ggaaaatcct tttgatggaa ctactagcga aaatcaaaaa ggtgtagcaa gaatggttgt
    55021 tggaaaaggt caaataattc tgttgtaatg gttagcaatt attaatattt ttgaatttgt
    55081 tacaacaaaa gtaaatagga ggtataaata tggtagggat tatcctagca agtcatggac
    55141 aatttgctga aggaatctta caatccggtt caatgatctt tggcgaacaa gaaaacgtca
    55201 aagccgtgat tttgaaacca agtgaaggtc cagatgactt gagagccaaa ttggaagaag
    55261 cggttgcttc ttttgataat caagacgaag tgttattctt agttgattta tggggcggaa
    55321 caccgttcaa tcaatcaaac acattattcg aagagcacaa agataaatgg gcaatcgtca
    55381 gcggtttgaa tttaccaatg ttgattgaag cctacgcatc acgcttttca atggaatctg
    55441 ctcatgaaat tgcagcacac atcattgaaa cagcaaaaga cggtgtaaaa gtaaaaccgg
    55501 aagaattaga accggcagaa gcaccgaaag cagcagttga agacgcacaa cctaaaggag
    55561 cacttccaga aggaactgtg gtcggagacg gaaaaatcaa atatgtatta gcacgtgttg
    55621 actcacgtct gttacatgga caagttgcga cagcttggac aaaagcagtg caaccaaacc
    55681 gtattatcgt tgtttcagat gcagtatcaa aggatgatct gcgtaagaga ctaatcgaac
    55741 aagctgctcc tccaggtgta aaagcaaatg ttattcctat tagcaaaatg atcgaagtag
    55801 caaaagaccc tcgttttgga aataccaaag cattgctttt atttgaaaat cctgaagacg
    55861 tattgacagc tgttgaaggt ggcgtagaca tcaaagaatt aaatgttggg tcaatggcgc
    55921 attcgatcgg taaagtcgtt gtaagtaaag tattgtctat gggacaagaa gacgttgaag
    55981 cgtttgagaa gcttgaacaa aaaggtgtga aattcgatgt acgtaaagta cctaatgatt
    56041 cacgcgataa catggatgat attttgaaaa aagcaaaagc tgaattagca aaagcgtaat
    56101 aaataatatt aaaatttata ggaggcttat catgtctatt atttcaataa ttttagtcgt
    56161 attagttgcc tttctagctg gtatggaagg tattcttgat gaatttcaat ttcatcaacc
    56221 actagtggca tgtacattga tcggtttagt taccggtaac ctcgaagctg gtatcgtact
    56281 tggcggtacg cttcagatga tcgctttagg ttgggcaaat atcggtgccg ctgtagcacc
    56341 agatgctgca ttagcatcag tagcatcagc aattatttta gttttaggtg gacaaggtgt
    56401 taaaggtgtt ccttctgcga tcgcgattgc cgttcctttg gctgttgcag ggttgttctt
    56461 aacaatgatc gtacgtacaa tcgctgttcc aatcgttcat ttgatggatg cggctgctga
    56521 agaaggaaac atccgtaagg ttgaaatgtg gcacatcatt gctgtatgtt tacaaggggt
    56581 tcgtatcgcg gtcccagcag cagcgttgct atttatccca gcacaaactg tgcaatcatt
    56641 ccttgaatca atgccagcat ggttaacaga tggtatggct atcggtgggg gaatggtcgt
    56701 agctgtaggt tacgctttgg taatcaacat gatggctaca aaagaagtat ggccattctt
    56761 cgttattggt ttcgttgtag ctgcaatttc tcaattaaca ttgattgctc taggtgcttt
    56821 aggtgttgca ttagctctta tttacttgaa cctttctaaa atgggtggtt catcaaataa
    56881 tggaggcgga agcaactctg gtgacccttt aggcgacatt ttgaatgact attaatcttg
    56941 aaggaggaaa ataaaatggc agaagaaaaa atcaaattat caaaaaaaga tcgtttagct
    57001 gttgcgtggc gctctacctt cattcaaggt tcatggaact acgaacgtat gcaaaacggt
    57061 ggctgggcat tttctatgat tccagcaatc aaaaaattat acaaaacaaa agaagaacgt
    57121 tctgcagcat taaaacgtca cttggaattc tttaatacac acccatacat tgcttctcca
    57181 attttagggg ttacattggc tctggaagaa gaacgtgcga atggcgcgcc tgttgatgat
    57241 gtagcgattc aaggggttaa agtaggtatg atgggtcctt tagctggtgt tggtgaccca
    57301 gtgttctggt ttacagtacg tccaatgcta ggtgcactag gtgcttcatt agctatggga
    57361 ggaaatatcc ttggaccaat catcttcttc ttaggttgga acattattcg ttgggcattc
    57421 atgtggtata cacaagaatt tggctacaaa gctggttcta aaattactga tgacctttct
    57481 ggcggattgt tacaagacgt aacaaaaggt gcttcaattt tagggatgtt cgtattagct
    57541 gcccttgtag aaagatgggt atcaatcaaa ttcttaccag ttgtatcaac tgtaaaatta
    57601 gataaaggtg cttacatcga atgggataaa ttgccttcag gtggtgaagg aatcaagagt
    57661 gcatttgaac aagttaataa tggcttagcc ctttctcctg aaaaggtaac aacattacaa
    57721 gacaacttag accaattgat tcctggttta gctgcattag gattaacatt gttatgtatg
    57781 tggttgctta agaaaaaggt ttctccaatc gttatcatcc ttggtttatt cgtagtcggt
    57841 gttgttggac acgtcatcgg acttttataa tccataaaaa tatagctcgg gcgttgtccc
    57901 gagctttttt tatatagtat actgttcata aacaaatatc tggagggaga aaatggttca
    57961 atcaatcaat acaaaagtag acttggtaat tgatgctact tcgtttacgg gtctgacaga
    58021 ttacgggcaa atcatgatag gtgataatgg ttttgagttt taccatgcgc gagatagacg
    58081 caaatatatc caaattccat gggaagaagt ggattatgta ctagcatcag tcatgctaaa
    58141 gggaaaatgg attcctcgat atgccattca aacgaaaaaa aatggtacat acacattttc
    58201 ttccaaagaa cctaaaaaag tgcttcgtgc gatcagagaa tatgtagatg aagatagaat
    58261 ggtacaatca ttgagtttct ttgatgtagt gaaacgtggt attcgtagta tgtttaaacg
    58321 caagtaaaaa ataaagaaaa cttctaagag gaggttttct ttattttttt actttgcaga
    58381 agaaaatatg aaatagcaaa accaattatt tgtccccttt aaatcccata tgctaaaatt
    58441 gattagcaaa gaaggaggtt atattatgag ttggttatgg acattgattg ttggagccgt
    58501 gatcggagca attgcaggtg cgatcaccag taaaggaaat tcgatgggct gtgtaacgaa
    58561 tatcattgct ggactagtcg gttcaagtat tggacaagcg attttcggcg aatggggacc
    58621 aaaagctgca ggtatggcac ttattccatc tattttaggc gcagtgattt tggtagcagt
    58681 tgtctcattt ttctttggaa aacgatcata agtttttaca aaatagtaaa ctaaaaggag
    58741 ttgcagcgag actgtgactc ctttttggct ttatttattt aaaataaaaa gaagttttcc
    58801 ggaaattttt atttaactgt cgtgtacgaa gaaaagtttg ctataatgga aaaaagcgtg
    58861 caaagaaaga gggagtttca ttatgatgct acgtgtagaa aaattgcgca aaaaaatgca
    58921 agaagaaaat ttggattcat ttttggttac cagtccgtac aatcttcgtt acttaacgaa
    58981 ctttacaggt acgacaggat tagctgttat tactttggaa aaagcatttt ttattactga
    59041 ttttcgttat accgagcagg cggcagcgca ggctcaaggg tttgaaatta ttaaaaatgt
    59101 cggacctatt tttgatgagg tagcaaactt agtacgcaaa gaagaactgc actcattagc
    59161 ttttgaggaa acaacagtct catttttaga atattcggtt ttagaagaaa tcatcgatgc
    59221 ggaattagta cctgtttcac agatgatcga agaactcaga gaagtgaaag atgaagaaga
    59281 aatcgctatt atcgaaaaag catgtcatat tgcggatatg gcatatgatc acatcctgaa
    59341 aatgatccaa ccgggcatga ctgagattga agtcgcaaat caactagact tttatatgcg
    59401 ttctcttggc gcttcaggtg tttcttttga tacgatcgtt gctagcggat tgcgttcggc
    59461 tatgccgcat ggtgtagcaa gcaaaaaaat catcgaacaa ggtgacttga tcacattgga
    59521 ctttggttgc tattacgaag ggtacgtttc cgatatgaca cgtacattcg ctattggtga
    59581 tcctggggaa aaattaaaag aaatttatca aatagtctta gatgctcaat tagcagttat
    59641 tgatgctgca aaaccaggaa tgactggtgt ccaattagat gcagttgcta gagattatat
    59701 ttcaaaacat ggttacgggg aagcatttgg acattctaca ggacatggga tcggtttaga
    59761 gatccacgaa ggaccaaacg tttcttctcg tgcagaaaag caatttgtac caggaaatgt
    59821 gatcactgat gaaccaggga tctacttacc aggaatcggt ggagtacgta ttgaggatga
    59881 cttgttgatc acagaagatg gaaatcgtgt gttgactcgt tcaccaaaag aattgatcat
    59941 cttatagttt catcaataga agaagtaagc gtaaaaatca gtgttcacag actttgttat
    60001 agaaaatcac tcgatttaat gatacactat agaagaactt ttaagctgta agagataata
    60061 aagttgggtg ttttctccaa ttcatagcag tttgcagctg atcggcggca gttttcttac
    60121 cacgtgatca ctatgccgca tcatagagaa ttcggatgta tctcgtgctt aggcaaaggg
    60181 aggaataaat aaatggcaga tgaaaaaaat ttgattttaa acgcaaacca agatttagga
    60241 gagatcgtga tcgctcctga agtcatcgaa gtaattatcg ggattgcagc ttctaaagta
    60301 gaaggcgtat acggaatgcg cggaactttt gccagcaatg tcactgaatt attaggacgt
    60361 gcagctcacg gaaaaggtgt ttacttagca aacgaggaag atggcttgaa agtagatctt
    60421 tactgttatc tagaatatgg tgtttcagtt cctaaagtag caatggaaat gcaggaacgg
    60481 gtcagccagc aagtcctttt catgacggat atcgatttat ctgaagtcaa tatccatgta
    60541 gtagctgttg ttcctgaaaa attagaacaa ccaacaatcg aagaactttt tgaagacgaa
    60601 gaggaagaga atgaataaag aattatcaag acacgagatt cgggaaatgg cattgcaggc
    60661 tttatttcca ttagacttca atgcagacct aacaaaagaa gatgcgattt tcaacgcaat
    60721 cgaattagac caccgcgaca tgatcaacga agatgaatca gagtttgttc ctgtttatct
    60781 tgatacgcta gttggcggtg tctgtgcaaa aaaagatgaa ttggataaag tgattgaaaa
    60841 acatttaaaa aacaattggc acatcaatcg gatctcaaaa atggatttgg tgatcttgcg
    60901 tatcgcgatt tttgaaatga cttatgtgac agatgtacca gcggctgttg ctttaaatga
    60961 agcaatcgag ttggcaaaaa catttagtga tgaccgttca cgtaaattcg tcaacggtgt
    61021 tttatccaat gtattgaaag aattagaagc tggggcgtaa gtcctagctt ttttctatga
    61081 atcatcataa acctgttata aatcgggaaa attctatggt agaatgaaaa cacaaaaaat
    61141 atctgggagt ggttagatgg cagaattgat taacggaaaa gaattagctg aaaaaatgca
    61201 ggcagagatt gctgaaaaaa tccaaaaatt gaaagataat ggtatccatc ccggattagt
    61261 cgttttattg gtaggggaaa atccagccag ccaaatctat gtaagaaata aagaacgtgt
    61321 agcaaaagaa atcggaatcc attcattggt agagcgttat cctgagacga tttctgaaga
    61381 cgaactactt gcagaaattg aaaaatacaa tcaagatcct agttttcatg gtatattggt
    61441 ccaattacca ttgccaaagc atatagatga agaaaagatc ctgttagcta tccgccctga
    61501 aaaagacgta gacggttttc atccgatgaa tttaggcaga ctccttgcgg gtaaaccgga
    61561 caagattcct tgtactccat acggcatcat gaaaatgttt gaagcttatt ctatcgatcc
    61621 ggcgggtaaa cgagcagtag ttatcggacg aagcaatatc gtcggtaaac cgatggctca
    61681 gctactcttg atggcagatg caactgttac tgttgctcat tctaaaaccg aaaatctggc
    61741 tgaactggca caagaagcag atattttagt cgtagcaata ggacgtggac attttgtcac
    61801 aaaagaattc gtaaaaccag gtgctgtagt gatagatgta gggatgaatc gtgatgctaa
    61861 cggtaagctg atcggtgatg tgaaatttga tgaagtggag cctattgcag gctggatcac
    61921 tcctgtgcca aagggtgtag ggccaatgac tatcacgatg ctgatgtatc aaaccgtaaa
    61981 atctgccgaa gcttttggag caggtgaata gatggcacaa gaatatttaa ctgtcactac
    62041 attaacgaag tatttgaaaa gaaaatttga tgccgatcct tatttagaac gcgtatattt
    62101 aacaggcgaa atatcgaatt tccgtttacg tgccaatgcc catcaatatt tcagcttaaa
    62161 agatgaccat gcaaaaatat ctgctattat gttcaaagga gcattccaaa aattacgatt
    62221 ccagccaaaa gaaggaatga aagtccttgt cgttgggcgt atttcattat atgaagcggg
    62281 aggttcttat caaatctatg tagagcacat ggagcctgat ggaataggtg ctttatatca
    62341 agaattggaa gaacgaaaag aaaagctgat gaaggaaggc ctttttcaag ggcctaaaaa
    62401 aatgctgcca cgtttcccaa agcgaatcgc ggtccttacc agtccaagcg gagcggttat
    62461 ccgcgatatc atcacgacgg tgaaaagaag atatccaatt gtccaattgg ttttgttccc
    62521 aacagttgta caaggaaacc aagcagcgga caatgttgtc aggaatatcc agagagtaga
    62581 agagatgggc aatttcgata caatgatcat cggtcgtggg ggtggttcga ttgaggattt
    62641 atggccgttt aatgaagagc gggttgctcg ggcgatttat caagctaata cgccggtgat
    62701 ttcatctgta ggacatgaaa cagataccac gatcgctgat ttagtagcag atgttcgggc
    62761 tgccactcca acagcagctg cagaattagc tgttcctgtt ttgtcagaag agttgatgcg
    62821 cattcaagaa cggcaagcta gattgcagca ggcgtttgta cgccagatcc agcgcaaaca
    62881 agaacggttc gagcgtgctc gacgttccta tgtatttcgg cagcctgaaa gattgtatga
    62941 aggtcagacc atcaaattag accagttgaa acagcgatta tatcaagcta cacagcaaat
    63001 ttatcatgcg aaagaaaaac aaacgatcgc attaagccac caattggaac aagtggctcc
    63061 gctttatcga gttaaagcag ctcgccaaga aactgcttat ctagaaaaac gcttagaaga
    63121 gaaaatccaa caatatatga aacaacagca gcagcgtttt gctcaagctg ttcaatctct
    63181 tgatttgttg agtccattga aaatcatggg aagaggctac agctatacga cgttaaatga
    63241 tcaagtagta aaaagtgtca ccgagattca tcaaggggat ttgctgacga tccattatca
    63301 agatggaatc gttaaaggac aagtacaaga gatagacaaa ggagaataaa aatatggaaa
    63361 atccaacttt tgaagagtca ctgcaagaat tagaaaaaat tgtcatgcag ttagaacaag
    63421 gagacgttcc attagaatca gctctagatt cgtttaaacg aggaatggaa ttaagcaaac
    63481 attgccaaga tacattagct aaagcagaag agaccttgac gaaaatgatg acagaatcaa
    63541 atgaagaagt tgattttgac ggaaacgagg aaagctgaga tgagattaac tgacttttca
    63601 gctattcatc tacctgctgt agaaaaagaa atcttgtctt ttttagatga gcatacaacg
    63661 gatagaggac tctatgatgc gatgagttat tcagtgaaag caggcgggaa aagaatacgt
    63721 cccttattac ttttaacggc cgttgcttcc tttgatgagc ctattgatgt tcccgtctat
    63781 caagtagcag ctgctttaga aatggtgcat acgtattcct tgatccacga tgatttgcct
    63841 gcgatggaca atgatgatct tcgtagagga aaacctacca atcataaagt attcggcgaa
    63901 gcattagcta tattggccgg agatggtttg cttacaggag cattccagct aatcagtatg
    63961 gcacacttag gtaattctcc taagcttctg ctgcttcagc aattagctgt ttgtgcggga
    64021 tcacaaggta tggttgctgg gcaagctgca gatatcgagg gcgaatcgaa aaagctttct
    64081 ttagaagaat tagcatttat tcatgaaaga aagacagggc atttgattcg ttatgccttg
    64141 ctggctggtg gcatattagc gaagcaacct gaagaaatct tattgctact tcaacgatta
    64201 gccgaacatt taggtttagc ttttcagata agagatgatc tactcgatgt gattggtaca
    64261 acgaaaacat tagggaaaac agctggtaaa gatgaacgta tggaaaaaaa tacttacccg
    64321 cgtttattag gcctagaaaa gacacgtgag gcgttggaga ttgagctgtt atccgccaac
    64381 aagatcatag acaaattaga agaggacgtt ttttcttttg atggcgggct gatgcgccag
    64441 atgatcaagc aatttgatgt ggagaaatga gggaaagaat ggaaaaagaa cgcgtagatg
    64501 tattagcggt caaacaagga ttatttgaaa caagagaaca agccaaacgt tcagtgatgg
    64561 ctggtttgat ttacaacgaa aaaaacgagc ggtttgataa accgggagaa aaaattccag
    64621 tgagtagtga attaagagtc aaaggtaaaa aacttcctta tgtttctcga gggggattaa
    64681 aattagaaaa agcactcaaa gcatttgatc tatctgttga aggaaaaaca ttgttagata
    64741 ttggtgcatc cactggcgga tttactgatg cagctttgca aaatggcgca aaaatgagtt
    64801 atgctttaga cgttggctac aatcagctag cttggaaaat aagacaagat cctagagtcg
    64861 tcgtaatgga aagagtgaat tttcgttatg caaaacccga agactttacc ttaggaattc
    64921 cagaagttgc tgttatcgat gtttctttta tttcactaaa actgatgctg cctccattac
    64981 atgctatttt aaaagaagag ggagaagtga ttgctttaat caaaccccaa ttcgaagcag
    65041 gcagagaagc tgtagggaaa aacggaattg ttcgtgaccc tcagacccat caaaaagttt
    65101 tagaagacat tttgtcattt gcggcacaag gtggatatga tgtgctggaa ttaagttatt
    65161 ctccgatcac ggggggagaa ggaaatatcg agttcttggc tcacttgagg aaagtacccg
    65221 aaagcggaac aatcaattca gctattaata tggcagaagt ggtttcaaat gcacacgaac
    65281 agtttgacca taaataaatt gtaactgtga aaatcaagtg agaagtatgc ggattcttct
    65341 ttattatacc aaggaaataa gctatcattg attaagaaga atatgctaag gagcgaagac
    65401 gtaatgagaa aaaaagatcg gcatcgtttg attactcgat tgttgagtga gcaagatatc
    65461 cgaaagcagg aagaatttgt tgaaatcctg aaaagcaaag gaatatctgt tactcaagct
    65521 acgatttcca gagatataaa ggaactgaaa ctgatcaagg taccggcttc agatggcggc
    65581 taccgttata gcataccagc tgaaacaaac gaagatgtaa atactaaatt ggaaaaacta
    65641 ttaaaagacg ctttcgtggc agttgaccaa atggaaaaat ttgttatttt gaaaacattg
    65701 ccgggaaatg cttcggcagc agcaaatttg attgataaac gttacaagaa agaattattt
    65761 tcgattatca atgatgacga taatgttttg atgattacac gaactgaaga ccaggcagtt
    65821 ttattgaaga aagacttcct gcattacctt taagttgagg agcgaatgtg atgctacaag
    65881 aaatcagtat tactaacttt gcgattattc cggaattgcg gctttctttt cacgaaggaa
    65941 tgaccgcgct gaccggagag actggtgcgg gtaaatccat tattatcgat gctttaggtc
    66001 tgttagcagg aggaagaggt tcaagcgatt atatacgtca aggagcagaa aaatgtgtgc
    66061 ttgaagggtt gtttgaacta ccaaaacaag aaggattctc tgaactgatg gttgaattag
    66121 ggatcgaaac agatgaggac aatctgattg ttcgacggga tatgtcctta actggaaaaa
    66181 atgtttgtcg agtgaatggt catattataa cattagctaa tctgagaaga atcggcagtt
    66241 atttagtaga tatccaagga caaaacgaac atcaggaact gctccagcct gaatcacatc
    66301 ttgctttatt ggatcgtttt ggagatgtag ctttccaaca gaagaaaaag agttatcagc
    66361 aagaatatat ctcttatcgt gagctggaaa aaagggtacg aaaagtgcag caaaatgaaa
    66421 aatcctatgt tcagagaata gatatgctcc atttccagca agaagaaata gctgctgctg
    66481 atttgcaagt cggagaagaa gagaaattaa aagaagaaag agaaaaactt agcaattatc
    66541 aaaaaattgc tgatggatta gctgcaggtt acggagcact gacgaataat gaacaaaaca
    66601 gtgtagatgg tgttggcttg gccgtttcag aactgcaagg gatcgcccat ctagatgtgg
    66661 agtatgaagc aatttatgaa aatatccaaa gtgcttacta tttgctgcaa gatgcaatcg
    66721 gcgatatgag tcgtcagatt gatttattgg agttagatga gagtcgttta gaagaagtta
    66781 cgcaacgttt agaattaatc cgacagttga aacgtaaata cggcgaatcc attgagtcaa
    66841 tattggctta ctatgacgaa atcaccgaag agctagcttc ttctgatttt tcagaaggtc
    66901 aattggacaa aatgaaagag gaactagagc aaaaagagct tctacttcag caacaagccg
    66961 cagatcttca tgaagcgcgt aaaaaaatcg caaaagaatt ggaaaaatcc attctgcatg
    67021 aattgaaaag tctgtatatg gaaaacactg agtttgaggt acgtttctta aaagaagaaa
    67081 atagacaatt gaatcatgat ggatttgacc aaatcgaatt ttacattacg accaatccag
    67141 gagagccact gaagcctttg gtgaaagtcg cttctggtgg cgaactgtct cggatgttgc
    67201 ttgctttgaa aactattttt tcttctgagc aaggtgtgac aagtattatt tttgatgaag
    67261 tggatacagg tgtgagcgga agagttgcac aggccatcgc agataaaatt tctcaaatat
    67321 cgaaatactc tcaagttttg tgcatcactc atctgcctca agttgctgca gtcgccgact
    67381 atcaatatta tattgtgaaa gcagtgattg atggacgtac gcaaacttct gtttcagagt
    67441 tgaaaacaaa agaaagagaa gaagaaattg cacgtatgct ggctggaagt gagattacaa
    67501 aactcacact cgaacatgca aaagaactat tgaaactcgc aaaaaggacc tgagccacct
    67561 cgcagtggtt caggtccttt tcagcagctg atagctatat tttattttta catgacactc
    67621 attacagcag tcaatacaac agatccaatc gttaaaatca gcattgtcca aatgacaaat
    67681 tttgttactt tagcaaaagt acttgtttgt tttttttcac gcattgtttt caacctcgtc
    67741 attaattagt tgattcaagt gtacaatctt ttttccattt ccacaagagg gcttttttat
    67801 aaaaacttcc ctttttttaa ataataggta gttacgatac aaataaataa tgttaataga
    67861 actagccata taaaggcatc atccctttca gcaataggta acttaatgtt cattccatag
    67921 atactgccga cgattgtcgg tatagttaaa ataatcgtta aagaagttaa aattttcata
    67981 atattattca gattattcga tacgattgct gaaaaagtct gattcatttg ttctactagt
    68041 tttaattgaa tgcgagaagt agtcattgcc tgctctgttt ccaccaatac atcacgtaaa
    68101 tgatttttca aagcatgatt ttcttggaaa agtttatttt gcgctagttc tttcaatgca
    68161 tctaaattag cagaagtcgc ttctctgaaa taaacgaggc ttttttggat atccatgatt
    68221 tgataaagtt gtttgttttc agtggatact tgaagtttgg cttccaaagt atcgcattga
    68281 gattgaagcg tagctaaata actgttgtaa gagagtgtga cctgccaaat gaattgaaag
    68341 aagatattga gattaggcga aatatcactt tttggaaagg tctggctaaa gactttcttt
    68401 aaaaacagtg gttcatgatt cgtaattgtg ataagcttct ttttgggcgt caaaataata
    68461 gagagcgggt atgtatccac ttgaaaataa ccgctaggac ttgttttagc aaaaggatat
    68521 tgtaacaata ataacgctgg ctttgtcaac tttgattgat tgaattcttc tgtacgggaa
    68581 ttttctgcat cgtccaatat ggaagtgatg taatctgacg gaatttcaaa ttgatgtgtc
    68641 agctgatgaa tctcttcttg attaggacgt tctacacaat accagatcgt ttggtcagtt
    68701 tcctttccgg tattacgcag tttctcatta tctaatgtaa aatatttgat catgattttc
    68761 ctcctgttgc ctgtttcttt tattataacg gatagggaat tggaatacat ggaatgtgtt
    68821 tgtaagatat agaatataac tgcataaatt taaataaaat gaaacagttg tgtaaagtat
    68881 atacagtata cttgaagcaa cgataaaaaa ggagtttacg ttcatgggca cattcacacc
    68941 acttatcttg ttttggtata tttacccggt aatcgttttg tttggttgcc aatttcttgt
    69001 aaaattattt tcgttaaatc gtcgttttaa aataaaagcc cctgatttgg cgattccttt
    69061 tttgtggggc ggtatgcatg cattgtctag aaatacaggg acaatttcta tcttaccgtt
    69121 tttctttatt tctgttttgc taatgggaat ttgtattgct gttttccaag catattatta
    69181 tgaagaaatt atttatccgc gttatttcaa gatgacttgg cgtttggttt ttctgttgac
    69241 aatcgtcttg tacgctgtct tgatcattgt gaacatactt tcttacctat gaaaaaaata
    69301 gaaaagctgt aaaaagtctt ttaaaaggct ttttgcagct tgatttttaa aaaaatgttt
    69361 atgaataaaa aaagttgttc ccggatttcc cagaaaaggt ggtagaaagt gggggattgt
    69421 ggtagactaa ttttagttag tggaggaatg gggggctttc aatgttgatg ggtgaattcc
    69481 aacataatat tgatgcaaaa ggacgtttaa tcgtgccctc aaaacttcgt gaagaacttg
    69541 gcgaaaagtt tgttctgaca cgcggattgg atggctgtct tttcggctat ccgatgagcg
    69601 aatgggaaaa tctggaagct aaactgaacg aaatgccgtt ggctaaaaaa gacgcacgta
    69661 cttttgtgcg attcttctat tcggctgcca ctgaatgcga acttgataaa caaggacgaa
    69721 tcaatatacc cagcacgtta agaaattatg cagctttgac aaaaggttgc gtagtcatcg
    69781 gtgtatctaa ccgaattgaa atttgggatg agacacgatg gcaagatttt tctgcagcag
    69841 cagaagagaa ctttgacgaa attgctgaaa gtatgattga tttcggacta taagaatagg
    69901 aagaggctga ctaatgactg aaacatttca acactataca gtcatgttga aagaaacggt
    69961 agatggattg aacatcaaac cggatggcgt ttatgtagac tgtacactcg gcggtgccgg
    70021 acatagtgaa tatttattaa gccaactaag ttctaaaggg catctgtatg cgtttgacca
    70081 agatcaaaaa gcaatcgatc acgccaagct gcgtttagct tcttatgtcg aacaaggtat
    70141 ggtcacattt atcaaagcga acttcagaga attagaagaa cgcttgagtg agcatgtaga
    70201 taaggtagac ggcattttgt atgatctagg ggtttcctct cctcagctag atgaagcaga
    70261 acgtggattt agttatcatc aagatgcacc gttggatatg cgcatggatc agtcagctcc
    70321 tttatccgct tatcacgtaa ttaatgaata ttcctaccat gaattagtaa agattttctt
    70381 ccgctatggc gaggagaaat tttccaaaca aattgctcgt gaaatcgaac gagtacgaaa
    70441 aacaaaacca atccaaacaa ctggtgagct tgtcgaaatc attaaacaag tcatcccagc
    70501 tcccgcaaga agaaaaggcg ggcatcctgc aaaaagaatt tttcaagctg tgcggattgc
    70561 agtaaatgac gaactcggtg ccgaagaggc ctctttagaa caggcaatcc ggttattgaa
    70621 agtcaatgga agaatcagcg taatcacatt ccattcattg gaagacagaa ttgtcaaaag
    70681 tatgtttaaa gaatatagta cggtacaaga tctaccaccg ggacttcctg tcatacctga
    70741 cgaattccaa ccagaactga aagtcattac tcgtaaacca atccttcctt cagaggaaga
    70801 gctaacagaa aacaatcgat cacgcagtgc aaagttacgt attgcagaaa aaataagaat
    70861 gaaagaggag tagaatgatg gcagaattaa agaaaatgca agattacgaa tatgatttac
    70921 ctgaattggt ggatcagccg gaacaacaaa tgcctgattc ttcttcgaat caagaaatca
    70981 ttcttccaca atcaccggca aaacgattaa agcagatttc tgctttggaa aaaattgctg
    71041 tggcaagcgt ggcgattgct attgttgctt tatgtgtttt aacagttatg ctgcgcacaa
    71101 atatcagcgg agctgaaaaa gaaatcacgt caatacaaac agaaatcaat gataaaaagc
    71161 aagaaaaaac gagtttagaa caagaaaaaa acgaactttc tcgtactgaa cggattaaac
    71221 aaatcgcaga agaaaaagga ttgtctatta atgacgacaa tttaaggaaa gtgaagtaaa
    71281 tgagtcttaa aaataaaatt cggcggttta tggaaaagaa aaatctaaat ccgatgaaca
    71341 atcgcaaaaa agtaggtatc attttatttg ctacgagtat tggattgttc tttttatttg
    71401 ccgtccgttt ctcgtatatc gttattggag gtcatgttgc tggtacctca ttagctgaaa
    71461 aaacaaaaca gttgtaccaa ggaagtgaag tagtaaaagc aaaaagagga acgatttatg
    71521 atcgtaacgg tgtggcgctc gcagaagatg cctcctctta ttcaattaaa gcgatactct
    71581 caaaaacata tacctctggg gataaaaaac tgtatgttga agaaaagaat tttgataaaa
    71641 tagcagaaat cctgcataag aatctttcta tagacaaaaa agatgcactg aatattttag
    71701 aggacggcgc aaaaaaagag ctgtatcaag ttgaatttgg tagctatggg aaaaatatct
    71761 cccaagaaac caagcaaaac atcgaagcgg acatgaaaaa agaaggtgtc gctggtcttt
    71821 attttgtcga ccatcaggct cggatgtatc caaatggcgt cttttcttct cattttattg
    71881 gatacgcagt tccagacaaa gatgagaatg gcttagttgg taaactaggt ttggagtctg
    71941 cttacaatga tatcttgagc ggtaaagatg gtaagattat ttatcaaaaa gataattttc
    72001 aaaatcctct gccaggtaca gtggcagaag aagaaaaagc tgtcgacgga caagatatct
    72061 acacgacttt agacagcaga ctacaaagtt atttagaaac actgatggat caagtaaatg
    72121 aagaatatca gccagaagaa ttgacagcag tcctgatgaa agcaaaaacc ggagaaatct
    72181 tggcaatggg acaacgacct actttcaatc ctgaaacaat ggaaggattg actggaaaag
    72241 atgctatctg gcgtaatttc ttggtacaag atagttatga accaggatca accatgaaag
    72301 ttttcactac tgcagctgct atcgaagaag gagaattcaa cgagaatgaa accttccaat
    72361 ctggaaaaat ccaagtagaa gatgctacga tcaatgacca tgactttggt gaaaaaggtg
    72421 tgctgaccat gcgtcaagct ctttcatggt caagtaacgt cgggatggtc atactggaac
    72481 agcgattagg cggacgatgg tataactatt tacaaaaact gggatttgga caaagtactc
    72541 attctggatt agatgatgaa gtaaacggtg ctttacctac attaaatatt gtcgaccgag
    72601 caatgagtgc ttatggacaa gcggtaggtg tgacgaattt ccaaatgatg aaagctttca
    72661 cttctattgc gaataacggt acaatgattc aacctcgata tatcagcaaa gtggtggatc
    72721 cccaaactgg agaagagcga acaactcaaa cagaagttct agggcaacct ttttcaaaag
    72781 aaacaacaga aaaagtccgt gaatatatga gagatgttgt cgaaagcgaa aactacggta
    72841 gtgcttatgg tgtatatagt gtacctggat acaatgtatc ggcaaaaaac ggaacagccc
    72901 aaatcgcttc tgatacaggg ggatatcaaa caggagatac agcctacctg tattcgattg
    72961 tggagatggt tccttctgaa gatccagact atgtcttgta tctaacaatg aaacacccta
    73021 agacatatga tcgaatggca ttggctaaaa tcgcaaatcc attgatgaaa cgggcaatgg
    73081 attttaaaga aactgaagaa gattcagata cagaaacaaa aacagaaaaa gtatccgtag
    73141 ccgattatcg taatcttgaa gcggacgttg cagcagctga tgctcaaaaa agtggactgc
    73201 aacctgtagt gatcggtaat ggtaaaaaag tacaaaaaca atctactgcc aacggtgatc
    73261 agttgatctc tggagaaaaa ctgatcctat atactggtgg tgataagctg atgcctgacg
    73321 taacaggatg gtcaaaagca gatatcatga agctggggaa aatcctcggt attgaagtta
    73381 gttttgatgg agatggttat tgtgtcaaac aagaacttgc tccatatgaa aaaatcactg
    73441 aagacaaact tagttttact ttagaagaat aagaagagaa ataggagaga aaagagcatg
    73501 gaatggacac aagcattgat tcccattgtc agcagttgtg caatgacaat tgccgcaatg
    73561 ccgctattta ttggttattt tcaaatgaaa aagcaaggtc aggcgattcg tgaggaggga
    73621 ccaaagtggc acaatagcaa agccggaact cctacaatgg gcggcttagt gtttctgatc
    73681 ggctctattt tgacaggaat ttgggttgga gcttggcaaa aacagctaac tcctactctt
    73741 ttcatcttgc tttttgtatt agcgttatac ggagtaatcg gctttcttga tgattttata
    73801 aaaatattca agaaaagaaa catgggactg aactcgaagc agaaattgat tggacagatt
    73861 ctagggggaa tcatctttta tcttgtttac cgttctgaag gttatccagg tgtattgaat
    73921 ttcttcggac tagatctacc tttaggaatc atttatggta ttttcgctct cttctggctt
    73981 gttggatttt caaatgcagt aaatctgaca gatggcatcg atggattagt tgctggctta
    74041 ggaagtatct cttttgcagc ttacggtcta attgcttggc atcagcatca gtatgatgta
    74101 ttaatcattt gcttaagtgt tttaggaggt ttactgggtt tcttcgtcta caacagaaaa
    74161 cctgccaaga tttttatggg agatgtcggt tcattagcgt tgggcggact tttagcggca
    74221 atttctataa tgctaaacca agaatggaca ttgcttttga ttggtttgat ctatgttatg
    74281 gaaacagcaa gtgtgatgct tcaagttact tcctttaagc ttacaggaaa acgaattttt
    74341 aaaatgtctc caattcatca tcactttgaa atgtgcggat ggtcggagtg gaagattgat
    74401 acagtttttt ggttgatcag cattgtgact tcgttgatca cattatggat cgtttggtag
    74461 gagatgacgg gaaatgaaaa aaatatcaac atatgaaaat aagaaagtgc ttgtcttagg
    74521 actcgcaaaa agcggagtaa gtgcggccaa attattacat gaattgggcg cacttgtcac
    74581 cgttaatgat ggaaaacctt ttgacgaaaa tccggaagca caagagctgc tttctttagg
    74641 gataaaagta ataacaggta gtcatccaat cgaattgttg gatgaagaat tttcattgat
    74701 ggtcaaaaat ccagggattc cctacagtca tcctttagta gcaaaagccc aagaaatggg
    74761 tattccggta attacggaag ttgagctagc ttacgaagta gcggaatgcc caattattgg
    74821 gattacagga acgaacggaa aaacaacgac aacaacgatg acaggactac tactgaatgc
    74881 aggagcagat caaggaattg cacgtttagc gggtaatatt gggtatccag caagtggtgt
    74941 agcgcaagaa gcaaaatcag aagataaaat tgtgatggaa ttgtctagct tccaactcat
    75001 gggaatcaca gatttccgcc ctcatatagc ggtgattacc aatatctatg aagcacatat
    75061 tgattatcat ggtacaagaa aagaatatgt caaagctaaa tggaaccttc aaaaaaacat
    75121 gacagaaaaa gattatctga tccttaactg gaatcagtca gaactacaag aattagcgca
    75181 aagaacaaaa gcacgcgtac tgcctttctc gacaaaagaa gtgttggaag acggtgtgta
    75241 tgctgacgat tactcaatat actataaaaa agaaaaaata atggaaatat ctgaacttgg
    75301 cgtaccaggt aagcataatg tagaaaatgc actagctgct atttctgtag caaaattgta
    75361 tggtatatca aatgaagcta tacgagaaac gttgcatttt ttccatggcg taccacatcg
    75421 tacgcaatat gtaggagaaa tccaaggcag aaaattttat aatgattcaa aagcaaccaa
    75481 tattttagcg actaaaatgg ctctaagtgg atttgaaacg tctaaggtcg tgttattggc
    75541 tggcggatta gacagaggaa atacatttga tgaattaatt ccttcattaa aaggaatcaa
    75601 agcaatggtc gtatttggcc aaacaaaaga aaagttgatg gatgctggaa aaaaagcagg
    75661 catcgagaca atagtaacag ccgattctgt agaacaagca gttcctttag cattagaaaa
    75721 cagtacagat ggtgatgtag ttttattatc accagcgaat gccagctggg atcaataccc
    75781 aaattttgaa actagaggaa acagattcat ggaagctgtg aaccgattaa aatagaaaaa
    75841 gtagaagcga gcgataaaaa atgaaaattt tggttacagg cggaggaaca gggggacata
    75901 tttatccagc tcttgccttt gtcaattatg taaagactca agaaccgaat gctgaattca
    75961 tgtatgtggg agcaaaacga ggtctagaaa acaaaatcgt ccctgataca ggaatgcctt
    76021 tccatacctt ggagattcaa ggatttaaac gaaaaatttc catgcataac atcaagacgg
    76081 tccgattgtt tcttaagagt atccgtcaag caaaaaaaat cctcagtgat tttcaaccag
    76141 atatcgttat cggtactgga ggatatgttt ccggagcggt agtgtacgct gcagccaaaa
    76201 tgggtattcc aacagttatc catgaacaaa acagtgtacc aggtgttacc aataaatttt
    76261 taagccgata tgtggatcgg atcgctcttt catttaaaga tgcggcttcc tttttttctg
    76321 aaaacaaagc agttcttgta ggtaatcctc gagcacaaga agtagcagat actaaaaaat
    76381 cagatatttt gaaaacattt gatttggatc cagaaaagaa aacagtcttg atttttggcg
    76441 gtagtcaagg agcacttaaa atcaatcaag cagtatcagt ttttttaagt gaatatattc
    76501 cttcttctta ccaagttttg tatgcttcag gagatagata ttatgaagag atcctaaata
    76561 aaataaatcc tgaaatacaa aatattagtg tccagcctta tatcaaaaat atggcagagg
    76621 tcatggcttc cagtgatctg ctggtggggc gtgctggtgc aacttcgatc gcagaattca
    76681 cagctctggg gttaccggca gtgttggttc ccagcccata tgttacgaat gatcatcaga
    76741 ctaaaaatgc aatgagtctt gttcacgcag gagcagcaaa aatgattgca gataatgaac
    76801 taacaggtga atcactaagt cagacagtca acgaaatcat gggtgatgaa gaattgcaaa
    76861 agcaaatgtg ccgagcttct aaagaacaag gaatccctga tgcttcaaaa cgtctttatg
    76921 acttagtaaa acaaataatc aaaaaataaa ggcggtggtc ttagtgagta agaaaaaaga
    76981 accaaaaaaa ttgtctcatc cgtcttctga tgaaaacaat ttgactcctt ggcaaaaggc
    77041 taaccgaaaa tatctggcag aacaagagat gaaaaaccaa gagccaaaaa aagaagacat
    77101 aacattagat acaccccttt cagattctga agaagaaaaa acggttcaag aggaacagca
    77161 agaagaaagc cagtccgaga aaaaaatcga attttttgaa gagatcaagc aaaagaaaaa
    77221 cggtggacca tataacggtt cttttttgaa ccggctgccc aatttaaaaa gtcaacggca
    77281 caaagtacta tttcgtcggt tagctttgat catcactgta ttgggtatac cgctgatttt
    77341 tttgatctat tatgtttctc cttatagcaa attacaagca gttgcagtat caggcaataa
    77401 gacagtcaac agccaagaaa tcatctctga tacaaaattg tcattaggag aaaatgtttg
    77461 gggacagtat tttcatcgat ctacttatat cgatcgcctt aaaaaagcac agccaagaat
    77521 cgaaacagca aatatacatt tcaaagggat gaatgaattc gatttggatg taacagaata
    77581 taaagagatt gctttgatcg caaaaaacaa tcaatactac ccagtgattg aaaatggaac
    77641 agtattagat gaaaaagtag caaatcctac aaaaaatctc cctatcttgg aagagttcaa
    77701 agactctgca aaaatcaaag aattaacaaa gcaatacaat cagttatcat cagaattaca
    77761 aaaagcaatt tctgaaatca agtacacgcc aagagcaagc aataaaaatc tgatccaatt
    77821 gaatatgaat gacggcaatc aagttattgt aaatatcaat aatcttgcga accaaatgaa
    77881 atattattcg caagtagcca aagatatgga tgaaaaaggt gtgatcgaca tggaagttgg
    77941 tatcttctcg catccttacg gtagcactca agaaacggaa gaatcgggcc aatcggaaga
    78001 aacaactgaa agtgaagaaa atgcggatca aacaaacgaa tcaagtgaag aggcagaaac
    78061 gcaaaaagca caaacacctg gatcgtctag cacaaacgga tcatctgatt caaatgattc
    78121 aagtgaaaca agtcaaatag aagataatcc aagtacaact ccgtcaagtt taaatgaaaa
    78181 ttgataaaac aactttaaaa agtaagaatg tactttctaa aaaccagtaa tttatggtag
    78241 aattggaagc agtgaatata tctattaata agtatatttt aaaacggacg ctagttgttc
    78301 gcttgtatat ggaatagtaa gtaggaggga atcccattca tggcaaaaac aggaatgtat
    78361 gtaggccttg atattggaac gacatctgtt aaagttgtcg tggctgaata tatcgacagc
    78421 caaatgaata ttattggagt aggaaacgca aaatcagaag ggattaaccg aggcattatc
    78481 gttgatatcg ataaaacggt ccaagcgata caacgagcag tacgacaagc agaagaaaaa
    78541 gcaggtatcc agatcaaagg cgtaagtgtc ggtttgccag caaacatgct tgaagtagaa
    78601 aattgccagg gaatgattgc agttaacgga gattcaaagg aaatcaccga tgaagatgtc
    78661 agaaatgtgg cttcagctgc ccttgttcgt tcaatacctc ctgaacgtca aatcgtgtca
    78721 atattgccac aagattttac tgtcgatggg ttcgagggaa tcaaagatcc tcgtggaatg
    78781 atcggcgtaa gattagaaat gtacggtctg ttgtttacag gacctaaaac gatcatccat
    78841 aacatacgta aatgcgtgga aaatgccgga ttaatcgtca acgaaatggt gattactcct
    78901 ttagcgctga ctgaatcaat tctttctgac ggagaaaaag attttggtac gatcgtcatt
    78961 gatatgggtg gcggccaaac aacaacggct gttatgcatg ataagcaatt gaagtttacc
    79021 aatcttgacc aagaaggtgg cgaatttgtc actaaagata tctctattgt attaaatacg
    79081 tcatttaaca atgcagaagc gttgaaaata aactacgggg atgcataccc agaacggaca
    79141 tcaccagatg aagaatttcc agtagatgtg attggtcagt cagaaccagt gaaagtcgat
    79201 gaacgctact tgtcagaaat tatttcagct cgaatggaac agattttcaa caaagcaaaa
    79261 gatgcattgg accaaatcga agcattagag ttgccaggtg gcgtcgtatt gacaggcgga
    79321 gctgctagtc ttcctggtgt tgtggacttg gcacaagaaa tcttcggcgt aaatgtaaaa
    79381 ttgtatgttc caaatcacat ggggctgaga aacccggtat ttacaaatgt aataagtatc
    79441 gtggattatt cagcaaactt gagtgaagtg tatcaattgg caaaaattgc tgttacgggt
    79501 gaaacctcag cagctcgtca aatggtagtt gaacaagaaa caacaaacac atatgagagc
    79561 tatgaagcac ctgaagaaac aatctacgat gagccggaac caaaagagtc cggagaaaat
    79621 gtaaaaaata aaatcaaggg tttctttaca aatatttttg attaattcat cctgggagga
    79681 ataagatatg gaattctcaa ttgataataa tatcaatgac ggcgcagtaa tcaaagtcat
    79741 cggagtcggt ggtggcggtg gaaatgctgt aaaccgaatg attgaagaaa acgttaaagg
    79801 tgttgaattc attacagcca acacagacgt gcaagcatta aaaaattcaa aagctgaaac
    79861 agttatccaa ttaggcccca aatatactcg tggtttaggt gctggttctc agccagaagt
    79921 tggacaaaaa gcggcagaag aaagtgaaca atccttacgc gaagctttag acggtgcaga
    79981 tatgattttc atcactgcag gaatgggtgg aggaaccggt acaggtgctg caccaatcgt
    80041 tgcaggtatc gcgaaagaat tgggcgcatt gactgttggt gtcgtgacac gtccattcac
    80101 ttttgaagga ccgaaacgtg gccgttttgc tgcagaaggt atcgctcgtt tgaaagaaaa
    80161 tgtggataca ttattaatta tctcaaataa ccgtttatta gaagttgtag ataaaaagac
    80221 accgatgctt gaagctttcc gtgaagcaga taatgtttta cgacaaggtg tacaaggtat
    80281 ctctgatttg atcacagcgc caggttacgt taaccttgac tttgctgacg tgaaaacagt
    80341 gatggaaaac caaggtacag cattgatggg gatcggtgtg gctagtggag aagatcgcgt
    80401 agtagaagca acgaaaaaag caatctcctc tccattgctt gaaacatcta ttgatggagc
    80461 tgaacaagta cttcttaaca tcacaggcgg tttggatatg acattgttcg aagcacaaga
    80521 tgcttcagat atcgtagcaa atgcagcaac tggcgatgta aatatcattc taggtacatc
    80581 tatcaatgaa gaaatgggcg atgaaatccg tgtgacggtc atcgcaacag gtatcgatga
    80641 atcaaaaaag gaacgcaagt ctagccgacc agctagacaa gcacaaatgc aatcacctgc
    80701 tcaaaagact gtattagata tggatcaagc taaaccaact tcttcagaag aagaaaacag
    80761 ttttggcgat tgggatatca gacgtgaaca aaatgttcgt cctagagttg atgattccaa
    80821 ttttgacaat atcgaaaaaa aagaatttga tacattcaac cgcgaagaaa caaaatctca
    80881 tggcgatgat gaattaaata cgccaccgtt tttccgtcgt aaaaaataaa ggagaggaag
    80941 agcacatgat tgctgacaac ttgcagaaaa tcaagcaaga aattcaggat tcgtgtgctc
    81001 ttgttcatcg tgatccgaaa gaagttacat tagtagctgt aacaaaatct gttgaatccg
    81061 ctcaagctga agaattggtt agagctggcg ttatgaattg tgcagaaaac cgagtagata
    81121 aattattaga aaagaaacaa gatttatttg attttcctga aataaagtgg catttaattg
    81181 gtaatttaca gcgcagaaag gtaaaattga ttgtaaatga aattgattac tttcatgcgt
    81241 tggacagttt aagattagca gaagaaatcc agaagcggtt agagaaagaa ttatcctgtt
    81301 ttattgaagt aaatgtttct ggtgaggaat caaaacatgg aatttcacca gatgagcttt
    81361 taccgtttgt ggaatcttta gctgcctgca caaaaatcaa ggttgttggg ttgatgacta
    81421 tggcgcctaa agaagcttct gatgagcaaa tccataaagt gtttggtacg ctgaaagaat
    81481 tgcgtgatct tgttcaagca aaaggttatg cccatgcacc atgtagtgaa ttaagtatgg
    81541 ggatgagtca agactttcaa attgcgattg aagaaggtgc aacatttatc cgtgtaggaa
    81601 cagcgctatt caaagacgaa taaaggagga acaaaaatgc cgcttttaaa cagaggagca
    81661 attgctaatt ttttcggatt agctgatgag gaagagtacg aataccaaga ttatcctgaa
    81721 acaacaaaaa aggctgtaca gccaactaaa aaaaatacaa cacagaatca atcaactcat
    81781 tctgtatctg ctgcgaatac tcatgaaaaa caaaaaacgg cgacttcacg tcctgtaacg
    81841 catgaaagta ttcagccggc tgaaaagaaa aaagtaattg aactacatca atcacctaca
    81901 aaaactgtag cgaaagaaag aacagcttca agaacctcta cacaacctaa agcaaatctt
    81961 gctggaaaaa tcactgtaat ggaaccaaga gcttattctg aagctatggc gattgctaaa
    82021 cgaatcattg ctggagaagc aaccttagtg aattttcatt tagtagaaga aaaacaagcg
    82081 agaagaatcg ttgattttct aacaggaaca gtttatgcac tagatggaga tatcaaacgt
    82141 gttggagatg agatttttct ttgtacaccg actgggatgg agattgacag ttcaaccgct
    82201 caatcttttg cagatgcgaa tttgtttgat ctgtaagagg aggaactacg atttatacta
    82261 ttgcactatt acttcattta cttcaacggg cagcctattt ctatagcatt atcttgatgg
    82321 tatatgcatt gctctcttgg tttccaggcg ggtatcaatc agggctagga cgattattag
    82381 ctaagatctg cgaaccgtat atcagtttgt tcgatcgtct gcctttgagg attggaccct
    82441 tggatttcac aattttaggg gcaatcctga tcttgaactt agccgtacaa ggtttagcac
    82501 agatcgttat atggataact gtccatttag tttattgatt gaagcaacaa aatctttatt
    82561 ctcagaatag ataggagggg aaaattttga tgcaaatgta taccagcact ttcgggcaga
    82621 tgaacgtaca tttatcgatt cggtaggcga ttggattgaa caggttcaag gacaatatgc
    82681 accctatctg accgaatttc ttgacccaag acaatcctat attttagaaa cactgattcg
    82741 acaaagcagt gatttgcgtt tcatgtttta tggcggatat gaacaggcag aaagaaaaag
    82801 atgtttgatt ttccccgatt attacgaacc tgtagaggaa gattttgaaa cagcattgta
    82861 tgaaatccat tatcctagca aatttgccag cctaagtcat gggaaaatcc ttggaacttt
    82921 agtgggaacg gggatcaaac gctcttactt tggcgatatc atctcggacg gtgatcgctg
    82981 gcaagtattt attgcaaatg aggtggatca ttttgttgct gcacaagtaa caaagattgg
    83041 aaaggttgct gtacgcttgg aaccaatcaa atacacagaa atgattatgc cgaaagatag
    83101 ctggacacaa gaaagaggaa cagttagttc catgcgacta gacagtgtga tctctgagat
    83161 ttataatatt tccagacagc ggtccaagca gctgatcgaa gctggtaaag taaaagtgaa
    83221 ctggacagaa aatacaagac ctgattttgt acttgaacta ttagatatta tttcagtcag
    83281 aggttatggc agagtccaga tccaagaact tgaggggaag acgaaaaaag aaaagtacag
    83341 ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg gtttactcat ggctttaact
    83401 ccattagata tccaaaataa gacattcccg acaaaaatgc ggggatataa tcaagacgaa
    83461 gtagatgatt tcttagattt agttgttcgt gactatgagg aattgactca aagaaatcga
    83521 gaattagaaa aagcagtcaa acattctgaa gaaaaacttg agtacttcaa tgaattaaaa
    83581 gatgctttga accaatcaat catcgtagct caagatacgg ctgataaagt aaaaacaagt
    83641 gcaagcaagg aatccgaagt gatcgttact tctgcacaaa acaaagcaga tgagttagtt
    83701 gcgaacgctg aaaaacgtgc acatcaatta acaactgatg cagaagaaaa agcaagaaaa
    83761 atcttgacag atgcaacaga aaaagcaaga cagcttgcga cagaaactga agatcttaag
    83821 aaaaaaacac gagtattcca tcaacgtatc agcttgatgc ttgagtctca attagaacaa
    83881 gtgaaaagtc cggaatggga tgaaatttta caaccattct ccagctacgt gactgacagc
    83941 catgaagtga tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga tactgatgta
    84001 aactcagaca caggagtcat agaagcacct atgacggcat ttgatacaca ggctattgat
    84061 atctcgatcg tgcctggtga aaatgaaaac gagtagaaca gaaaagcact ttgttattct
    84121 taaagcgagc cgatgagagt ggaagttcgg taagacactg catggtgaaa gatcctctac
    84181 ttgagacctg cttttccgaa attagagtaa gaagcagcgg ctgacctcgt tattggtcac
    84241 agagagtttg cactagatag atgcaactaa atttgggtgg taccacggca tgttcgtccc
    84301 ttgcggctga acatgctttt ttgtgtccgg aaaacaaata aaggagtgta tggttgaatg
    84361 aaaatgaaag aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg taatttgcca
    84421 aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc gaatctacca aaaaagacaa
    84481 gagttgaacg aaggaaaacc tagctttgtt cttcatgatg gacctccata tgccaatggt
    84541 aatatccatt taggacattc attgaataaa atcagtaaag acattatcat tcgttcaaaa
    84601 tcaatgtctg gctatcgtgc accatatgtt ccaggatggg atacacatgg attgccgatt
    84661 gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa tgtgcatggc agaatacttg
    84721 gaaaaatgtc gtgaatatgc actttcccaa gtagataagc aacgagcaga tttcaaacgc
    84781 ctaggagttg caggagattg ggaacatcct tatgttacat tagatccttc ttatgaagct
    84841 gcacaagtac gcgtatttgg taaaatggct gaaaaaggct atatttacaa aggattgaaa
    84901 ccaatttact ggtctccgtc aagtgagtct tctttagcgg aagctgaaat tgaatataaa
    84961 gatgtaaaat ctccatctat ttttgtagct ttcaatgtca aagacggcaa agatattctt
    85021 gatgaagata cagcttttgt catttggacg acaacaccat ggacattgcc agcaaaccaa
    85081 ggtattgctg taaatccaaa atttacgtat gtattggtgg aagccgatgg ccgtaagttt
    85141 gtcgtagcga aagatttgct agaaacagtc caatcagaaa tcggttggga aaatgtaaca
    85201 gttctaaaag aatttgctgg acaagaaatg gaatatatga ctgcaagtca tccattctat
    85261 gaacgtgaat cacttgtgat tttaggcgat catgttactt tagacgctgg tactggatta
    85321 gtccatactg ctccaggaca tggggaagat gactatatcg ctggtagcaa atataaacta
    85381 tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag aagaagcacc tggatttgaa
    85441 ggtatctttt atgacaaagc aaatcctatg atcactgatc tattaaaaga aaaaggagct
    85501 ttgctgaagc tagatttctt tactcatagt tatcctcacg attggcggac gaaaaagcct
    85561 gtgatctatc gggcaactcc acaatggttt gcatctatcg ataaattccg tcagaatatt
    85621 ttggatgaag tagaaaaagt agagtgggtt atcccatggg gtaaaacacg tttgtataat
    85681 atgatccgtg accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg agtaccactt
    85741 ccgattttct atgctgaaaa tggagaagca atcatcacac cagaaacaat cgaacatgtg
    85801 gcaaaattat ttgctgaaca tggatcaatt atctggtttg aaaaagaagc gaaagaactt
    85861 cttcctgaag gatttaccca cccaggttct cctaatggcg aatttacaaa agaaaaagat
    85921 atcatggatg tctggtttga ttctggttct tctcatgaag ctgttttacg tcagcgacca
    85981 gaattatcat tcccagcaga tatgtattta gaaggatcag accaatatcg tggctggttc
    86041 aactcaagta tcacgactag tgtggctatc aatggtgtag caccatacaa atcagttatt
    86101 tctcaaggat ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt aggaaacatc
    86161 attgcaccag aaaaagtgat caaacaattt ggtgcagata tccttcgctt atgggtatct
    86221 agtgtagatt atgaagcaga tgttcgtgtt tctatggata tcttaagtca agtggcagaa
    86281 gtatatcgta aaatcagaaa tacgatgcgt ttcttattag cgaatacaga agatttcgat
    86341 cctaaaaaag atactgtttc gtacaatgat ttacgttctg tagacaaata tatgaccgtt
    86401 cgattgaacc aagtaatcaa agaaatccga gaagaagggt acgacaaata taacttcatg
    86461 catatttacc gtacagttat gaacttcttg acggttgatc tatcgtcatt ctacctggat
    86521 tttgctaaag atgtagttta tattgaagca gaagatgatt atcaacgtcg ttgcatgcaa
    86581 actgttttct atcaaacagc tgtagctttg acaaaattat tgactcctat cattccgcat
    86641 acagcagaag aaatctggtc attcctgaaa gaagaagagg agtacgttca gttaagcgag
    86701 tttcctggtt atgaagagtt tgcaaaccaa gaagaattga tggatacctg gactgctttc
    86761 atggacttcc gtgataatgt cttaaaagca ttggaagaag caagaaacag caaattgatt
    86821 ggtaaatctt tggaagcaaa actaactgtt tatccaaaac aacaagttcg tgaaatgtta
    86881 aaagctttgg atgcagatat tgcacaatta ttgatcgttt caccagacta ctttgaagtt
    86941 atggcagcag atgaacaagt gccagataac gctatggtat ttgatgatgt tgctattaca
    87001 gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa agatgtagga
    87061 gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa aaatcgttga agacttctat
    87121 cctgaagctg tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg tgtgacatgt
    87181 tctttgtcac accccctttt gttatcaatc gtttaatttt ccacgttcac gataccagtt
    87241 atctggttgc cagatccatt cgaatccgtc tttttcaagt agttcgaaag ctgctttagg
    87301 tcccattgat ccagctttgt agttgggaaa atccggttgt gtttggtccc aagcttttcg
    87361 aatgacatcc acgatatgcc aagattgagc gacttcttcc caatgagaga agttcgttcc
    87421 atcaccattc aacgcatcta atagtaattt ttcgtaagct tctgggctat tttcaaccat
    87481 ttctgcacta tttctaaatt ccaatttgat tggttccgtt tcaaatcctt gccctacttc
    87541 tttcccattc aaggataaag aaaatccttc agttggctga atatagatcg ttagaacatt
    87601 aggtggaagt gtcgtatcgt cacatggttc atcgacagat gttttgaata cattaacagg
    87661 aacttgtttg aatacgatgt tgatccgagt ccctttttca gtcaaacgtt tgcctgtacg
    87721 tacatagaaa ggaacacctg accaacggaa gttatcgata gtgaatttgc ctgcgacgaa
    87781 tgtttcagtc tctgattgag catccacttt gtcttcttcg cgatagccct tgaattgtac
    87841 accatccaat tcaccttgag catattgccc gcgaacgaag ttttctaaca cttcttcttc
    87901 gttataaatg cggatagctt tcaatgcttt gatcttttct gtacggattt ctttttcgga
    87961 aaatgctact ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat gattttgcac
    88021 catgtcttta agtgcgccac tatgatcgta gtagcccccg cgatcttcta caccgaggtt
    88081 ttcgccaaaa gtaatttgga tattgtcgat atagcgattg ttccattgag cctcaaaaat
    88141 attattggca aaacggatag ctgagatgtt ttggatcatt tcttttccta aataatgatc
    88201 aatcctgaaa atatcttgtt ctgggaatac ttctctgatt tgctggttca attcaaaagc
    88261 agactggtaa tcagaaccga acggtttttc tatgatcaaa cgattgaagc cattttttgt
    88321 cataatattt tgtgatttca aatgagaaac gatcgttcca aaaaattgag gtgccatagc
    88381 caaataatag acacggttac cgtttaattg atagtgtcca tctaatcggt cagacaattc
    88441 ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg gattgatagt aaaaatggct
    88501 tgcaaaggta gttgcttctt catctgaagg attcaatgca cggattgttt ctttgacaac
    88561 ttcacggtag tgctcatcgc tccagggacg gcgagcggtt ccgattacag caaaatgctc
    88621 gcctaaattt ccttttctgt aaaggcggaa caaagacggg tacaatttac gctgggctag
    88681 gtcacctgta ccgccgaata tcgtaaacaa tacatttttt tcattagaca tgtggataca
    88741 ctcctttata ttttatcgac aaaaatcgtg ctggccgcct taaagctgac ggggattttc
    88801 tttctatcat tttggatagt gatcggtcct tcataagctg cgatgtcaac gatctcatat
    88861 tcttcgttga tattcaggtc aatagtgact aagtaatcca acaattcttt ttcatcaagc
    88921 actcgtgcga tacgcacttt tgtaccgaca ggataggact ccaatgtttg tcggcgttct
    88981 tcatggacaa cttcctcttt tttaggaatc gatcctccat gaggacaatg ttcaggatga
    89041 ttcaaatagt tttctaaatg atctgcaaga tgttccgaag tcacatgttc caatacttca
    89101 gcatcatcat ggacttcatt ccagctatag tctaaatgtt caactaaaaa aacttcccat
    89161 aagcgatgtt tgcgaatcag actgctagct ttttgcagtc cgcttgcagt caattgtaca
    89221 ccttgataag gggaatgttc tacaagctct tctttcacaa gtttagaaat catttcactg
    89281 acagatgcag ctgagacatc tagactagat acgatttgtt tattgttgac tttcgttgta
    89341 tctccaccta gttctaaaat gattttcaaa taatcttctc gatttggtgt catattcgat
    89401 catcctttca tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg ttaattgact
    89461 atttttctaa ataaaaaaca aaggattttt agacgttttt acaacaaaaa acgaaagatg
    89521 atagagaaga ctcattcttt cgtttataaa ggatatatat atacattggg agggatctat
    89581 ttttcagata acaacttata tgaagtgtct gcagattcgt cataaagagt ttgttcggga
    89641 taagaaaaga taagataaaa accatactga tcacgtacga ctaaacgata ttcatctatt
    89701 tctaccacag atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc agatgtaatc
    89761 tgtaattgtt gtttttgctg gctatcacta aagaaccatg taccttgata ctttgagagt
    89821 ccttctgact tttccgcttg ttttttcttt ttcaagtaaa taaaacttga gagaacggta
    89881 atgagtgaac caagaaaata gatcattttt tttatcacca aatcactcct ttatgagaaa
    89941 ataatcgcat agacatattc tttcttcttt atttcattgt accgaataaa agctaaaatt
    90001 tctctaagac tttcgactgg tttttttact gtttttctac aaattatgat aggatacata
    90061 gtaggaagaa aggtgacata atttgaagta tcagcaagtg gaaatagctt tttttattga
    90121 ccgcccgaat cggtttatag cacattgtat gaaaaaagac ggagaaataa ttattgcgca
    90181 tgtcaaaaat acaggtagag gaaaagaggt cctgatacca ggcgctgaag tggctattgt
    90241 atttgctcct ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa aaaagaaggg
    90301 tgactggttt aatatcgata gtcaattgcc taatcggctg gcaattgatg gtattttaga
    90361 cggcacgatc cttttaccag gattaactgg tccatttacg gtatacaagc gtgaagtaac
    90421 ttatcttcac tccaaatttg atatttattt agagacggtg gtcggacaaa aagcatttgt
    90481 tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt gcttttcctg atgcgcccac
    90541 actcagagga ttgaaacata taggagaatt aacgtatgcc gcacaagatg gttatgccgc
    90601 ttatgtcttg tttattgctc agttcgaaca tcttcatctg gcaacgatcc atgaagaaat
    90661 gcaaccagca ctagctgata tggttcgaca tgcgcagcaa agcggagttc aaatcctcgc
    90721 ctataattgt caagtatcgg cagatgaggt aactgtcaag caggccattc catttgatgt
    90781 agatatccct tttgaagatc ctatacaata gaaagaaggt aaaataatga tcaacttagg
    90841 tattatcgga acaaattgga ttactcatca atttgtccaa gcagctttaa gcacaaaaaa
    90901 atatgaattg acagcggtat attctagaca tttggaaaaa gcacaggaat ttggttctca
    90961 ttatgaaggg gatatcgaat tcgcaacaga tttgaagact tttttcaata ttactcatat
    91021 ggacaccatt tatattgctt ctccgaatag tcttcacttt agtcaagcta agcaagcaat
    91081 tttggcagga aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa aagaaatgga
    91141 tgaaatcatc catttggcaa atgaacacaa tgtgtatttt tttgaagcag caagaaatat
    91201 ccatgaatca ggttttaaaa agattgccga ttacttacca ttaaaagacg agataatcgg
    91261 tgcaaatttc agctatatga aatattcttc gcgctatgac caagtattag atggagaaga
    91321 accgaatatc ttctcgactc atttctcagg tggtgcattg atggatttag gtgtttacct
    91381 tgtatatgca gctgttgctt ggtttggaat gccaaaagaa gtccattatt tcccaagaaa
    91441 gatttctact ggtgtagatg gtcttggatg ggggatctta cgttatgaga attttgatgt
    91501 atcgatccag ccaggtaaaa tcggtgattc ttatttaccg tcagagattt attttgactc
    91561 aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc atgatcgcgc
    91621 gcataaagaa atcattgatt tggcggtaac agctgcagaa aatccaatgg cagatgaagc
    91681 agaggatttt gccaatgtca tggctcatcc gaaagatcca gcttggggat tgttgtatga
    91741 agagtggatc gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa gaaaaaatgg
    91801 cggcatcaaa ttcgatgcag ataatgagga agatttttaa tgaacgaatt tgtacaagta
    91861 tttcccgaaa attggcagaa aaaatatgag gataaagggt ttatctcacc ttctcttatt
    91921 caacgagcag tttttcagcc actaagtaat aaacaaagta tagtagcggt ttctcctaca
    91981 ggttcaggta aaacactggc ttatctttgg cctctactac taaacgtgga accaggtgaa
    92041 gcaagtgcgt tggtcatttt tgcttcttct caagaactag ctattcaagt agcagatgtt
    92101 gcacgtgaat ggggaaaaga caaagagttg aaagtccaat ctttggtggg cggagccaac
    92161 gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa tcttgattgg tacaccagga
    92221 agaatattgg aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa aacaatggta
    92281 tttgatgaag cagaccagct atttgacgct gggaacagcc aaatcattga tcaaattctt
    92341 catcaagctc caacagagta tcagctagct tttttttcag cgacagcaga tcgttccctt
    92401 gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac agcagaggac
    92461 gattctcgaa aaggactgag acattacttt ttacgtgtac cgatacgaaa gaaagatgac
    92521 tacttgagac gtctcacgca tatagaagat tttcatggtc tgattttctt taatcaactg
    92581 actgaattag gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt aggaagtctg
    92641 gcctctgatc agaacaagct actccgaaaa gcagcgctag aacaattcaa aaagaaaatg
    92701 gtcagagcac ttttgaccac agatgtggcg gctagaggtt tagatattac aggtcttcct
    92761 tatgtagtga atgcagaagt tccgttaagt gaagaagctt atttgcatcg ttcgggaaga
    92821 actggtcgaa tgggtaatga aggaatagta attacactcg tacaagataa taatctaaga
    92881 gatttaaaac ggcttttacg tccatcaaat ataacacttg aagagatttt tttatacgga
    92941 ggtaagctgc aaactgagca gccaaccaaa gaagatgcag ctcctgcagt aaataaaaag
    93001 tatgcgaaaa ctttttctgg aaaggagcag aacccagaat ataacaaaga aaaaataaga
    93061 aaaaaagtta aaaataaatc aaaaaaagag agaaataaag gagcaaggcg caaataagcg
    93121 cctttttatg ctatgattat gaaaacggga acaaaattgg ttgccagagg aggggttatg
    93181 tgaaagaacg tcaagaagag atcttgcagc tattgacaga aaaccaacaa ggattgacag
    93241 caagtgatgt agctgagcgc ttaactatcg atcgaagcaa tgcaagccga tatttaagtg
    93301 aactatacaa ggcccatcat attgtaaaaa ccgctggccg accagtcgtt tactctttgc
    93361 caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa gtgacttttg
    93421 aaacactcgt tggagaaaat gattctttaa aagtcagcat acagcaggca aaagctgcga
    93481 ttctttatcc accgcggggg ttgcatacga ttatttttgg agaaactggt acagggaagt
    93541 cgatgtttgc tgaatgtatg tatcattttg caatcgattc agagatgctt tctgcagatg
    93601 cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg ctctttggac
    93661 acatctttgg gatcaaaaaa ggggcttaca caggagcagc tcaagatagt cccggtctaa
    93721 tagccaaagc agacggcggt atattgtttt tagatgagat ccaccgttta ccgccggaag
    93781 ggcaggaaat gctgtttact ttcattgata aaggtattta ccgtccgctt ggagaaagtg
    93841 cacaagtaca tgaagcatct gttcagatca ttggggcgac gactgaatct tcagaaagtt
    93901 tcttatctac gttcaatcga cggattccta tggcaatcac cttgccgaat cttgcttcac
    93961 gttcactgga tgagcgttat gaaatcatct ctctttttat caaacaagaa gcgaatcgtt
    94021 tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc cttcatgctt tatgatgcgg
    94081 aaggaaatat cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa tcttttttac
    94141 attaccgtac tcatcatgag aaaaagctaa tcattcgaaa agaagaactt tcccttcaag
    94201 tacaaaaagg attactgaaa atcaaggaaa taccggaacg tctcgaccga ttcatggaca
    94261 gcaaaagtca gtatttgaca tttgaaccag gatttgctga tgttgtctgg tcacaagatc
    94321 cagaacgaaa catgcaggtc tataacgata ttgaggaaaa agtcacttct ctttccgaaa
    94381 ccggtgtgga gaacattgat ctagagaccc tcatttcaaa agatgtggat gcttatttcc
    94441 agacatatgt caaagaattg actaaaagtt cgattcccaa agatcttttg ccagatgaaa
    94501 tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa acggttagac cgtatttata
    94561 atgaaaaagc tcgttttgct tttgctttgc atctgcaaag tacattggat cgtgtgagag
    94621 aaggtcatat gatcgtccac ccagatttga ataacgtacg gaaaaatttt aagagggaat
    94681 tccaggtagc aatcgatctt tcaacgatca ttgaagaaga agaacaagtt gagattcctt
    94741 ttgatgaaat cggctttatt agtatgtttc tttctatcaa tctaggagaa agtgagcctg
    94801 ttaaagaaaa caaagtagat gttctcatat tgatgcacgg cagacagact gcttcaagca
    94861 tgttggagat ggcacaagaa ctattaggaa caaaagtagg gaaagctttt aatatgccac
    94921 tggttatgga agttcaaaca atgtatgaag aagtgttaca atatgtcaaa aactatcaag
    94981 agcatttgac gaatggccta ctcttgttaa cagatatggg atcattaaac accttcagtg
    95041 atttgattta tgaagagact ggcattcgga cgaaagctat cacgatgaca agtaccatga
    95101 ttgtgataga agcgatacgg atggcaagtg ttggaagaag cttagaagat atttatcaaa
    95161 atatccagct ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa aagtctgaaa
    95221 ctttacagcg taaaaaagcc gtaatcgtga catgctttac tggtgaagga gtagctgcca
    95281 aattatatca gcgtattatg ccagtgatta atcaaaataa ggtagaactg atccagatgc
    95341 agtttttaga acgtgaatca ttcaaaaaac acatcgatgc cttattggaa gaatatgaga
    95401 tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa tatcccattt ttttcagcct
    95461 atgacgtttt tgatgatgaa aaactaaata ttttaaagcg tatagctgat gatgagatcc
    95521 cgacagctaa aattgtcgat tcacttgctg gatcattaag cgatgtcttt tctattgatg
    95581 aactgatccg ttcattgcaa aagacagttc agcagatcca gaccgatttg tcgattatcg
    95641 tggaacctgg agtagatact ggaatcgtta tccatttagc cttcatgtta gacggattga
    95701 tcaaacaaga aagccatcgg caatttgaga aactgtctat tttctcaaaa atttatcgtt
    95761 tggaaatgga tatcgttcgg gcaaacttga tggcactaga acgaaaatat caggtaaaaa
    95821 ttccagaaga tgatatcgca tttcttacac aaatgtttct tgaaaataaa ataaaaaaat
    95881 gaacacacta atcatactgt ttacacacta aacatctgtg tgcgcactat aaaaaagagc
    95941 taaaaagcat gaaaacgcta tttcagctct tttttttatt ggcatgcttc ttgcgttata
    96001 taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat catgttagtt
    96061 tgttcagcag ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc agcagaagaa
    96121 aaagggatgg aagccgatat ttttgcggtc tctgcctcag atgcagataa taatttagaa
    96181 tctaagaatg tcgatgtatt attattaggt cctcaagtac gtttcatgaa agctcaattt
    96241 gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca tcaatatgca agactatggc
    96301 atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata aatcaagtat
    96361 gcagttgggg gtataacaac gtggaagatc aacaaaatct agaagccatc atggggttaa
    96421 tcatgtttgg cggtaatgca aagagcgatg caatggaagc gattgcggct gctaaaatcg
    96481 gtgattttga gttagcggat aggaaaatcg ctgatgcaga agaatcactt atacaagcgc
    96541 atcatgcaca aacagacatg ttgacacaag aagcacaagg aaatcatatg caagtgacat
    96601 tattgactgt tcacagtcaa gatcacttaa tgacatctat tgcgtttact gatttagcaa
    96661 aagaaatcat cgaactttat cgtcgcgtat acagcgaata aatacaactt cttttttgaa
    96721 cggaagaaga aaaatttttg aacggatttt ttattttgtt ataaggagaa ctctctttat
    96781 ataaaaaact tataggagga agtaaaaaat gaacggacta tcaagttgga tggagaaata
    96841 catcctgccg gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt tgcgtgatgc
    96901 ttttatcggc atactgcccg caacaatggc gggatcagtc gctgtaatga tcaatgcaat
    96961 tattcgtgat ttaccgcaac agtttaacag tacctatgct gacagtttag cagcagacaa
    97021 aggaatcttt gccgtattga atgtcatcat cggaatcaat ggttttgtct ggaacggtac
    97081 actagcaatc gccggattga tctttgcctt ttcttggggg tataatcttg cccgagctta
    97141 tggagtaaat gatctagctg gggggatcgt tggtttagct accttgattc aaggtatttc
    97201 ctttggtcca gcattatcag cagcattaga tgtgaatgtt ccttcaaatg tcgcagatgc
    97261 aatcaatagt tctgagattg gtgcaacgat tgcagatggc acactgtcag ttggattatg
    97321 gggttggcta aaactagatc atttgaatgg aaacgcttat tttacagtta tgatcatggg
    97381 agctatttca gtcattattt tttgtaaatt gatgcttgcc aacattacga tcaaaatgcc
    97441 tgattcagta ccaccagcag tatctaaagc atttgcagcc attttaccag cgacgatcgc
    97501 tttatacgtc attgctatta tcaattatat cgtaggtcgt gtagctgatg ggcaactgat
    97561 cattgatttg gtgcaaaaat atattgcaga accattccta ggattatctc aagggttggg
    97621 agcagtattg atcgtcacag tatttgttca agtattctgg ttctttggta ttcatggatc
    97681 aaatgtattg gcaccagtgc tagagggaat ctggggacaa gcacaactaa tcaatattga
    97741 tattttccaa aaaggttata acggaaaaac tggtacacca gccgtgttag atgcaatcga
    97801 agatggaaaa gcttatatgt gggtccgcgg atcgttcgat gcttttgcat ggtttggcgg
    97861 atcaggcgga acgatcgtct tactgatagc tatcttgatt ttctctaaac gtgcagatta
    97921 tctaacagta gctaaattat ccattgggcc tggtatcttc aatatcaacg aaccagtgat
    97981 gtttggtctg ccaatcgtat tgaatgcaat catgtttatc ccattcttga ttgctccagt
    98041 agtagcaaca gcaattggat ggacagctac ttatcttggc ctagtcgctc cggtatcgca
    98101 gcaagtcaca tgggtagtac cgccgttctt attgtcattc ttagcaacag gagcggattg
    98161 gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact ttcttgattt gggcaccatt
    98221 tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag atgaacgtga
    98281 ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga actgaaatga
    98341 ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa ggatacaatg
    98401 aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc tttgaaacaa
    98461 gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa gcacagcctt
    98521 ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa aaagatagga
    98581 tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg atcgtgttgt
    98641 atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca ggtctttttc
    98701 taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa gcaaaggaga
    98761 aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt tttacgataa
    98821 agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag taactagaaa
    98881 acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg ctcgcataaa
    98941 aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa cgaagaatga
    99001 attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg ttcattacac
    99061 agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt taggaacaat
    99121 cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg aagcaacgta
    99181 ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc tagaaggaat
    99241 ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt aggaaggggc
    99301 agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga aatgtttgat
    99361 ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg ttttcgtaca
    99421 cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct aacaagtcaa
    99481 gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat ggccggcatt
    99541 ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca gatcatggaa
    99601 aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc gccattctcc
    99661 tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag ttatcaacta
    99721 aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg tatggatttt
    99781 gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa ccaacgagct
    99841 ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg caattaccag
    99901 tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta tcagcttgca
    99961 acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt ttgcagcctt
   100021 gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc atgcggctac
   100081 ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat gatcacacct
   100141 tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc atttaaaaag
   100201 agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg gaatgaagga
   100261 atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga acaaacaaaa
   100321 ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg gtatcgtaaa
   100381 gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga agaaacgtta
   100441 agctcaatct tgccacagca acagccaatt cttaatgact atttttgata aaaaacgggt
   100501 gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa ggaaaatgtt
   100561 aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt ttagggtttt
   100621 cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt ttagatgaat
   100681 ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag gacctcccta
   100741 cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa cgttttgcct
   100801 aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa caagctacaa
   100861 ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct cctaagcgat
   100921 aggtcgctgg ttcaattcca gtcaggaacg tataaataac ccctgtatcc tttgcggtac
   100981 aggggtttgt tttgtatttg tgccaaaaat gtgccaaact agttatcatt tttatataaa
   101041 ctatcgaaca cagtattgat tttttcttta tcctgatctt caagctctcg aacaatatga
   101101 agataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga tacgctaagt
   101161 atatttactc cttgataaag taaaatagat gcatgtgtat gccttagtcc atgcaaagta
   101221 aattgctttt caatccctaa ttcttttaat tttttgcgca aatatttgct gacggcgttt
   101281 gatgaaacta atccattttt taagttgaaa aaaacaaaat tatgagggtt tttgatttca
   101341 aaattctcga ataattcttt ttgattgatt ttaaactttt ttaagagatc aatcgtatgt
   101401 ttatcaatgg aaattttcct atttgaagtt tcgttttttg tttttcccca ttcatttaat
   101461 ttataattcc atgttttatt aatagtgatg atttgatctt cgaaatcgat atcttcccat
   101521 gttaatccta gaagttcagc aaatcgcatt ccagtggcac cagcaactaa cacgagcata
   101581 ggagaagagt actgcgcaga aaggttttct tctacgagtt tcattaaaga tttaaattga
   101641 tcataatcta aatatttatc ttcttttggc ttcaatgaat cttttccttt gattactgct
   101701 tttctagttg gatcaaacgg aattaatcct tcttctacgg catctttcaa cgatgctcta
   101761 atatggttat taaacttaat aacggtggat tttacatggt ctttcgcata cttatttaaa
   101821 aagcgttgat atccaactct atctaaatca gaaatcaata ccgctggcat atatttcttt
   101881 atgttcatta acgtatcttc gtattttcta taagtgatag gagatactgt tccttcttta
   101941 taaagttgca tccaatcctc aaagtaatct gataataata gatttttgcg atccccttta
   102001 aggcctttgt tcaagttata ttctaattcg ttggcggcat cttttgcttc gccttttgtc
   102061 ttaaatcctg attttcttat cttcgtgtat tttccgtcat cttttttgta tgaaatttcg
   102121 tattgccaac tatttccacg tttgactaat cttgccataa ttgaatctac tctctttctc
   102181 tgatacaata ggcactataa agaagcctac tgtataggtt tgtttttctt agaacacgct
   102241 tgctttggac ggtgggcgtg ttttttattt attatacagt tgctttaaaa atagctgctt
   102301 tttcaaatga tactaaagga gagaagtgga tttctatttc tcccttttgg tttaacgtga
   102361 aatgagcagt tacatccatt tgttttcctg gagcaacaga tcccattgta ttttcgttgg
   102421 catatgtctc tgattttttg tcatctggtc catatacttc cacatctgta cctacaggga
   102481 tatctgaatc gccatcattt tttacggtat aagtaatttt tactacttgt gcaggttggt
   102541 tttcttcaaa ttgatttctt tcatcagtta gttctacact atttagtgta tattcagcat
   102601 caccaacttt tacagtgtca ccaatcttat agaaggtatc gcttttttct tctttagaag
   102661 atgaagcaga ggttgaagat ttagttactt tttcgccacc attatcactt gctttattac
   102721 tatctgatcc accatttaaa gcagaaccaa taattataat taaaattact gctaataccc
   102781 aaaaccatac ttttttgtaa aaaggtttac taactttata catttttccg tcttgaccca
   102841 taactttttt tgccatttaa atattcctca cttcttgtta taatatattt gcgatctcag
   102901 aaatgaggta tgagtccgtg ttgcagcacg ggcttttttt actgtgcata agagtatttt
   102961 ttcttgaaat atgactggca aacattaaaa cattctgttc ttaacttatt attgatagca
   103021 tagaattcca taaaattttc caatttgaac tgagattcat ctgttaattc attctcaata
   103081 aagatattaa gtagaatcat aattgcaatt ttatcagctt cagtttcgaa ttttgaatga
   103141 aaagttgtag agttatcgta cagtactgaa tattcaaaat gtgaagcaat gaaatgaccg
   103201 agctcgtggg ctaaatgaaa agcttcagaa ctatcttcgt gtagtttttc gtttaaaaat
   103261 actattcttg gttttggata ataaaaacct ggttcttcca tttccatata gattaacttt
   103321 aaattatact cactcagcat ttctttcaac tttaaataca tacaacccat cactccaact
   103381 attcattttc ctctaaagct ttagcaattg caatcgcttt acgcattgtc tccttagata
   103441 tttcttttcc atcaaaagaa aaaacagtat cgtcttctga taaatccaca tgtttagggg
   103501 tttctctttc ttctctacct agaaggtagt ctacagagac tccaaagtaa tcagctaacc
   103561 gagctaactc aatagaatta ggagtttgtc ttttccaact tcctaaatat ccattcgaat
   103621 acccgaaatt catttcgagc tgtctaatgg ataatccttt ttcttttgct aactccttta
   103681 ttatttcgta agtattcatt gataaatcaa cctttctgaa tgcttacaaa aaaagtttag
   103741 ataaataatg taaaaatagt tgacttatat acattattaa tctatactat gttttgtaaa
   103801 caagtttaac aactaaaaag acaacaaaaa atactattga ttaataaatg ccaaccgcca
   103861 agaaagcttt ttaaatcaaa gtttagatgt cttatttaac tatgcattta gtatagatta
   103921 ttaatctaat aaagtcaacg cagtttttta aaaagttgtt aaatttgttt acgaatataa
   103981 aagaaaggag agaagaatat ggaaaaaaca gtctcggcaa aaatcgaaga tttgaaatta
   104041 gacatactga aacaagcaaa agtggcgatg gaacacgcgg tagataaaga agactctgcc
   104101 atggttgcag ccatagcaga gattttagct cacgtttagt catcgttttt acggtcttct
   104161 ggaagctgac catagataac agcataatga atatctaaat aagcttgaac aatttctttt
   104221 ggcgaaattg attcgccttt agtagatact tgtgattcgt gatttagcca tgcaacaact
   104281 aaatccgcag cgatttcaaa cggcgttaca ctttgtgtca gttgccataa agaatttcac
   104341 aatatgtatg gtcgtggtaa taataccaaa gagcaatttg aggaatttat ggaaattaaa
   104401 aaatacaaaa aatcatttat taaaggaggc taaacaatga acaaggaaat gagccaaaca
   104461 atcaaggtac aaaaaatgat agatgatcta acacatggaa ttgatagcca agccgataaa
   104521 atcatcaagg aattgcaagg acaaaaagtt aaggatgcaa aaatgcttct caagactatc
   104581 aactttgaaa tgaatccaac aaaaagaaag ctcgccgatg tgttggaaga aaagttggct
   104641 tccgctatca acgagcaaga attactattt gaaaccgata cttttaacag ctgatgtttt
   104701 atagatgaca gtttcatccg aatctatatc atcgccgaga gaaaagaatg ttgcttttga
   104761 caaaaagccg ataagaccta caagcggtct tgatgttgca agagtagata ccccaatatc
   104821 accttgcaag gtattcacgt aaatttgaga agaatagaac attccatctt tttcttcgat
   104881 atttgacgca tcatcgtatc caacgaccaa agtatcggca aatattttga ttttttctcc
   104941 atcaagcata gtaattacaa attctggttt cataaatttt cacctcctta acaattattt
   105001 cagcctgtca cactgataag gaaattatac caaagaaagg aatgagaaat atgaatacac
   105061 cacaaatttt taatttcgag caaaacgaag ttcgaactat tttagtaaat gatgaaccat
   105121 attttgtagg aaaagatgta gcagacgttc taggatattc gaatccgcaa aaagctattc
   105181 gagatcatgt ggacttggag gataagacgc agaacgattc gttcaccgtc aatggaacag
   105241 cagttgtttt gattaacgag tcaggccttt acagtttaat cttaaaatca aaacttccct
   105301 ctgccaaaaa atttaaacgt tgggtaacga gtgaagtcct tccaacaatt agaaaaacag
   105361 gtagctattc aaacgtacct caaagttttg cacaagcatt gcgtttagca gcagatttag
   105421 aagaaaagaa ccaattactc gaacaacaaa ttgccgagta cgaaccaaag attagctact
   105481 tagatacgat tctttcatcg acagatacgg tagctacttc tcaaattgca gctgattacg
   105541 gaatgtcggc aattgctcta aacaaattgc taaacgagtt aggtgttcaa cataaagtta
   105601 gcggacaatg gatactttac cgaaaacata tgaaccaagg atacacaaaa tcgcacacaa
   105661 gtgagattcc gaaagccgat ggcggcacta aagttgtaat gaataccaaa tggacacaga
   105721 aagggcgagt gtttatttac aacttattaa tcgcagaggg ctattaccct caaatggatt
   105781 tagaggaaat tggttagaaa ggagttttag tatgactgac attgcagaaa tcactcaacg
   105841 agatagagaa aaaatcaaag aatatgtcga aagttcgaag ttcttaactt acaccatgct
   105901 tgctgaaaga tttggaatta gcaaaagcta cttatcttta attttaaacg gtaaaaagac
   105961 ttctgcagaa gcaaatagaa tcatagattc gattattact atgtacgaat tgtaaaggga
   106021 ggaacagcta atgcaatatc tagaagcgaa aatcccagtt ccagaaggct atgtaattat
   106081 ctcccaagtg gattatgagg agttaaaaaa agctgatgat actggtagat ggatgacgtt
   106141 gccagaagtg ctagaacgga ttaacagaaa atatgattgg tttacttcta gagttttaaa
   106201 gaacccaaga tatagaaata ttatcgatat cgaaaaaaat aaaaatggat ttgtctatta
   106261 tccagttgaa ggaagagaca catatctatt tttaagaagt aaaacacttg aatttttaga
   106321 aacaaatttt tcggaaatct taaggaggca agcggatggg aaaatttaat agagcgctag
   106381 tattcagcgc accgctaatc atctacgctt taggactttg gggaagcaga caagcgttga
   106441 taggaacgat tgtttacatg gtttggattt ttatggggct ggatgaagct gagtacaaaa
   106501 caaaaaagcc agtcgggagg gactgactaa tgaaaaaaag tttaatgact ataaacgaaa
   106561 aacaattgaa agaaaatttt aatgatctca tcaaagaatt tgtaaaagaa actggagaat
   106621 ttcctaatca aattcatcta gttgcggagg ggcatagcca gtatcaagct gtgaaatttg
   106681 agatgaagaa acaaatctat tgaatttagc agtacctcta cttgtaagaa catttattgt
   106741 aatgtttttt tcgactaaag attcatcgta tctaaaaacc aacgtagtaa tttttgactc
   106801 atacggtgga atggtaatag gtaatgacaa cggaggaaat tttgatagat cagcaccttt
   106861 ttttaaagat ttaccagaat acgcacgtat accatgtgga agttcgtcat acattgattt
   106921 taccgttaca gaataattat caccaatcat tgtaaaagca tttaaatgat caggaattcc
   106981 agaaatcgaa aactcaataa ttgtaacagg taaagaactg ttatttgtta acaatacaga
   107041 atctataatc ctgaatttat tttgatggta aacatctggt ttggaatcac tttctctatc
   107101 tatcaaccat tcttcgcatt cagcgaagaa atccaatttt aaattaaatt ttttgttttt
   107161 tctatctgta taggagatat aaaaagcaaa tgttgaaaat actagagacg taataggcaa
   107221 aataaaatct ttaatggttt taacaatgtt attccagtca aattgtttaa taaagtcaat
   107281 aagactcaat ttataccacc accatttttt atctacatta tatcaaagag gagagaagaa
   107341 ataatgcaag aattagtaat tttgaaaaat aaagaagctg tgactacgag tttgcaagtc
   107401 gcagatagtt ttgaaaaaga acacaaaaat gttttgagag atattgaaaa gttaaaagaa
   107461 gatgtgctca attttgagca gatgtttgtg gaaggtaatg aaccagattc atacggcaga
   107521 aatcgacgag ttttcttcat tagtagagat ggttttttct tgttggctat gggttttaca
   107581 ggaaagaaag ctatttactt caaacaaaaa tacattgaag cattcaacga aatggaagat
   107641 gttattcgta agaatactgt tcctcaaaca attgaagata tgatgatcta ccaactagaa
   107701 gaaatgaaag atgttaaaaa agatgtttcc atgcttaaag atactatgcg aattagtggg
   107761 caacaagagt ttgaaattaa acaaaaagga aatataaaag ttatggaagt tctagggggt
   107821 aaagaaagcc gagcttatga agaaatcagc aaaaaagtat tctcaaaatt ttggtctgaa
   107881 tttaaacgta ccttttcaat cccaagatat ggcgagttac ctcgtaagag attcgatgat
   107941 gctgtttcat ttattgaaat gtggttacca gaaactgcga tccgcatgga aatcgatcaa
   108001 ctgaacagac aacaaagact tttcggtgat gaaaatgaat agagctgaag cgctaagaat
   108061 cgggacggta attgctaatc gctggtggag acacaataaa ccaatcatcc taagccaaca
   108121 acatattgac aagcaaaaag catggcaaca aataaaaaag tgactccgcc ggcaagcaaa
   108181 gagtcacaaa gaaaacacat cataaggaga ttttagcata tggaaaaaga actttccact
   108241 ctagatcaat atttgactga tcctagttgg ggcaaatcga atatcaagga aacaaataat
   108301 cgaaaaatca gacgaaatct tttgacggat gaagaactag catgtgatca agacgatttg
   108361 ggaaattttg tgagtatttg ggatcatgtc tatcttatcc atttatcgag gaagtccaaa
   108421 aaacctgaat atatctatgt catcgaagat ggcttgattg atgcgctaga agagtatgac
   108481 agagataact tgattgatat ctcttattac ggatcaggta agaaatacat tgctgaaatg
   108541 gaggcagaat ttgatgagtg aaaacaaagg gacaacgact tttgaaaaac tttttagtcg
   108601 caagttaaat aaaatactca agaaaaaagg aaattttgat tatttatctt gggctcacgc
   108661 atgggagatt atgaaaaaga atgatccaca ggcaacggta actattaatg agtataaaca
   108721 ctacagagtt gtttctggaa ctcatcaaga ctttcttgtt gaggaatata aaccttttct
   108781 tatggatgaa actgggactt atgtatctgt ctcagtaacg gttaaaggac acacggaaac
   108841 cgaattattt cctgttttag attatcgaaa ccaaccagtt gttacgccaa atgctatgca
   108901 aatcaataac tcattgaagc gatgctttgt gaaagcattg gctctacacg gactgggatt
   108961 atatgtattt caaggggaag atattccaac accacctaga atcgatacaa agaaattaaa
   109021 catgctagag acgattctag aagctttcaa tgagcagatg ggtaaagata tgaccaaaac
   109081 cttaatcgaa tatgttaatg agcagacaga taaattaggg ctcttagctg ataacgttga
   109141 aactattgaa cagttaagct atgagcaatg tgccttgatg gagcgagcaa tagcagctaa
   109201 gagaaaagaa ttagataaga agtgatatga gtgtttaaac cattaatcga ttcatattca
   109261 gcggttctga aaaagttcaa aggaaaagac ataggtgcaa ctattaatga agaagtgaac
   109321 atcgaacgtt tgaagacgat gtacgacgga tatgatggcg atcggattat tgaagttcga
   109381 tttattgatc ctagacgttt cactgtacag caacgaaact tcatctatgc gctcataggc
   109441 gatattttca tcgatacagg catgccaacg gacttctgga aggaattctt ctactttcgt
   109501 tttgaaggcg tcacagggcg caaaataagc ctcaaagacg aatcgaatac aactgtgagt
   109561 gatgctaatg tcttagcaaa tatcatctta gatttcatct ttgaacatca tattcctttc
   109621 aaagaaggct atgagatttt accagcgaat caagaatatt acttctacaa atgcatcaca
   109681 aaaagagtct gctgcatctg tggcaaaaca ggagctgaca tcgatcactt tgacaaagcg
   109741 ctaggaagac gaaagcgcaa agaagttgat cattcagagt acacatttgc agcactctgc
   109801 agaatccatc acacagagaa gcacaaaata ggtgtgatta atttcaaaaa taaatatcaa
   109861 atcaaaggga tcaaattaaa ccagaaaaca atcaaaaagt taaatattgg agggtaaaaa
   109921 tgacagaaca tcgaagttat tatgcgatta taccagccaa cgtaaggtac gacaaaagac
   109981 ttaaaccaaa tactaagttg ttatacggag agataacggc cttgtgtaat gaaagaggct
   110041 tttgttgggc aggcaatgag tactttgcag atttatatgg tgtgaataaa gagaccatat
   110101 cgcgatgggt aagtgatttg attaagtttg gatacttgaa tcgggaaatc atttacaaag
   110161 agggtaccaa tcaaataatc aataggtacc tacgaattaa tcaataccct attgacgaaa
   110221 aacgcaatac ccctattgac gaaaaagtca aagataataa tacatctatt aataatacat
   110281 ttaataatac aaaagaatat ataagagagt taccgccttc gaaaaaatcg aaggctaagc
   110341 ccgtccgtca taaatacgga gagtat
//
LOCUS       DASHXG010000002       107482 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.002, whole genome shotgun sequence.
ACCESSION   DASHXG010000002 DASHXG010000000
VERSION     DASHXG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 107482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.002"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            309..1178
                     /locus_tag="U2R59_000121"
     CDS             309..1178
                     /locus_tag="U2R59_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8964554.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMINFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1387..2412
                     /locus_tag="U2R59_000122"
     CDS             1387..2412
                     /locus_tag="U2R59_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEM8964555.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2451..3401
                     /gene="manA"
                     /locus_tag="U2R59_000123"
     CDS             2451..3401
                     /gene="manA"
                     /locus_tag="U2R59_000123"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEM8964556.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3495..5198
                     /locus_tag="U2R59_000124"
     CDS             3495..5198
                     /locus_tag="U2R59_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8964557.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5200..7233
                     /locus_tag="U2R59_000125"
     CDS             5200..7233
                     /locus_tag="U2R59_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8964558.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7244..7684
                     /locus_tag="U2R59_000126"
     CDS             7244..7684
                     /locus_tag="U2R59_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8964559.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7884..9011)
                     /locus_tag="U2R59_000127"
     CDS             complement(7884..9011)
                     /locus_tag="U2R59_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964560.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9014..9691)
                     /locus_tag="U2R59_000128"
     CDS             complement(9014..9691)
                     /locus_tag="U2R59_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964561.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9955..11721
                     /locus_tag="U2R59_000129"
     CDS             9955..11721
                     /locus_tag="U2R59_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEM8964562.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11736..12173
                     /locus_tag="U2R59_000130"
     CDS             11736..12173
                     /locus_tag="U2R59_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8964563.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12186..13337
                     /locus_tag="U2R59_000131"
     CDS             12186..13337
                     /locus_tag="U2R59_000131"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEM8964564.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13399..14097)
                     /locus_tag="U2R59_000132"
     CDS             complement(13399..14097)
                     /locus_tag="U2R59_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEM8964565.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14090..15442)
                     /locus_tag="U2R59_000133"
     CDS             complement(14090..15442)
                     /locus_tag="U2R59_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEM8964566.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15665..17065)
                     /locus_tag="U2R59_000134"
     CDS             complement(15665..17065)
                     /locus_tag="U2R59_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEM8964567.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17226..17963
                     /locus_tag="U2R59_000135"
     CDS             17226..17963
                     /locus_tag="U2R59_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEM8964568.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18088..18567
                     /locus_tag="U2R59_000136"
     CDS             18088..18567
                     /locus_tag="U2R59_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HEM8964569.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18564..19331
                     /locus_tag="U2R59_000137"
     CDS             18564..19331
                     /locus_tag="U2R59_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964570.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19561..20130
                     /gene="lepB"
                     /locus_tag="U2R59_000138"
     CDS             19561..20130
                     /gene="lepB"
                     /locus_tag="U2R59_000138"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8964571.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20234..20836)
                     /locus_tag="U2R59_000139"
     CDS             complement(20234..20836)
                     /locus_tag="U2R59_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8964572.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20942..21411
                     /locus_tag="U2R59_000140"
                     /pseudo
     CDS             20942..21411
                     /locus_tag="U2R59_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21517..22101
                     /locus_tag="U2R59_000141"
     CDS             21517..22101
                     /locus_tag="U2R59_000141"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEM8964573.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22104..23177
                     /gene="prfA"
                     /locus_tag="U2R59_000142"
     CDS             22104..23177
                     /gene="prfA"
                     /locus_tag="U2R59_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEM8964574.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23170..24009
                     /gene="prmC"
                     /locus_tag="U2R59_000143"
     CDS             23170..24009
                     /gene="prmC"
                     /locus_tag="U2R59_000143"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEM8964575.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24002..24181
                     /locus_tag="U2R59_000144"
     CDS             24002..24181
                     /locus_tag="U2R59_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964576.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24203..25228
                     /locus_tag="U2R59_000145"
     CDS             24203..25228
                     /locus_tag="U2R59_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEM8964577.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25419..26663
                     /locus_tag="U2R59_000146"
     CDS             25419..26663
                     /locus_tag="U2R59_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEM8964578.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26816..27763
                     /locus_tag="U2R59_000147"
     CDS             26816..27763
                     /locus_tag="U2R59_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8964579.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27897..28526
                     /gene="upp"
                     /locus_tag="U2R59_000148"
     CDS             27897..28526
                     /gene="upp"
                     /locus_tag="U2R59_000148"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEM8964580.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28665..28907)
                     /locus_tag="U2R59_000149"
     CDS             complement(28665..28907)
                     /locus_tag="U2R59_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964581.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29028..29100
                     /locus_tag="U2R59_000150"
     tRNA            29028..29100
                     /locus_tag="U2R59_000150"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29061..29063,aa:Thr,seq:cgt)
     gene            complement(29219..29857)
                     /locus_tag="U2R59_000151"
     CDS             complement(29219..29857)
                     /locus_tag="U2R59_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8964582.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29980..30612)
                     /locus_tag="U2R59_000152"
     CDS             complement(29980..30612)
                     /locus_tag="U2R59_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEM8964583.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30963..31262
                     /locus_tag="U2R59_000153"
     CDS             30963..31262
                     /locus_tag="U2R59_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8964584.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31757..33922
                     /gene="acm"
                     /locus_tag="U2R59_000154"
     CDS             31757..33922
                     /gene="acm"
                     /locus_tag="U2R59_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HEM8964585.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34194..34679)
                     /locus_tag="U2R59_000155"
     CDS             complement(34194..34679)
                     /locus_tag="U2R59_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEM8964586.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34769..35114
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35159..35800
                     /locus_tag="U2R59_000156"
     CDS             35159..35800
                     /locus_tag="U2R59_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8964587.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35819..36454
                     /locus_tag="U2R59_000157"
     CDS             35819..36454
                     /locus_tag="U2R59_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8964588.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36472..37287
                     /locus_tag="U2R59_000158"
     CDS             36472..37287
                     /locus_tag="U2R59_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8964589.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37606..39042
                     /locus_tag="U2R59_000159"
                     /pseudo
     CDS             37606..39042
                     /locus_tag="U2R59_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            39231..41678
                     /locus_tag="U2R59_000160"
     CDS             39231..41678
                     /locus_tag="U2R59_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEM8964590.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41908..42975
                     /gene="rlmN"
                     /locus_tag="U2R59_000161"
     CDS             41908..42975
                     /gene="rlmN"
                     /locus_tag="U2R59_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEM8964591.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(43168..44271)
                     /locus_tag="U2R59_000162"
     CDS             complement(43168..44271)
                     /locus_tag="U2R59_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8964592.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44823..45371
                     /gene="aac(6')"
                     /locus_tag="U2R59_000163"
     CDS             44823..45371
                     /gene="aac(6')"
                     /locus_tag="U2R59_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEM8964593.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            45917..47578
                     /locus_tag="U2R59_000164"
     CDS             45917..47578
                     /locus_tag="U2R59_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8964594.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(47648..47995)
                     /locus_tag="U2R59_000165"
     CDS             complement(47648..47995)
                     /locus_tag="U2R59_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HEM8964595.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            48079..49020
                     /locus_tag="U2R59_000166"
     CDS             48079..49020
                     /locus_tag="U2R59_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964596.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            49021..50064
                     /locus_tag="U2R59_000167"
     CDS             49021..50064
                     /locus_tag="U2R59_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964597.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            50070..51140
                     /locus_tag="U2R59_000168"
     CDS             50070..51140
                     /locus_tag="U2R59_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964598.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            51130..52083
                     /locus_tag="U2R59_000169"
     CDS             51130..52083
                     /locus_tag="U2R59_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8964599.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            52095..53105
                     /locus_tag="U2R59_000170"
     CDS             52095..53105
                     /locus_tag="U2R59_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8964600.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(53390..54211)
                     /locus_tag="U2R59_000171"
     CDS             complement(53390..54211)
                     /locus_tag="U2R59_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8964601.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(54308..54586)
                     /locus_tag="U2R59_000172"
     CDS             complement(54308..54586)
                     /locus_tag="U2R59_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964602.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            54854..56863
                     /gene="metG"
                     /locus_tag="U2R59_000173"
     CDS             54854..56863
                     /gene="metG"
                     /locus_tag="U2R59_000173"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEM8964603.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(57342..57929)
                     /locus_tag="U2R59_000174"
     CDS             complement(57342..57929)
                     /locus_tag="U2R59_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964604.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            58104..59426
                     /locus_tag="U2R59_000175"
     CDS             58104..59426
                     /locus_tag="U2R59_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8964605.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            59581..60357
                     /locus_tag="U2R59_000176"
     CDS             59581..60357
                     /locus_tag="U2R59_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEM8964606.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            60350..60919
                     /gene="rnmV"
                     /locus_tag="U2R59_000177"
     CDS             60350..60919
                     /gene="rnmV"
                     /locus_tag="U2R59_000177"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEM8964607.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            60912..61796
                     /gene="rsmA"
                     /locus_tag="U2R59_000178"
     CDS             60912..61796
                     /gene="rsmA"
                     /locus_tag="U2R59_000178"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEM8964608.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            62247..62876
                     /locus_tag="U2R59_000179"
     CDS             62247..62876
                     /locus_tag="U2R59_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964609.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(63000..64109)
                     /gene="ugpC"
                     /locus_tag="U2R59_000180"
     CDS             complement(63000..64109)
                     /gene="ugpC"
                     /locus_tag="U2R59_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEM8964610.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            64318..64740
                     /gene="mgsA"
                     /locus_tag="U2R59_000181"
     CDS             64318..64740
                     /gene="mgsA"
                     /locus_tag="U2R59_000181"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HEM8964611.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            65063..65599
                     /locus_tag="U2R59_000182"
     CDS             65063..65599
                     /locus_tag="U2R59_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEM8964612.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(65639..67402)
                     /locus_tag="U2R59_000183"
     CDS             complement(65639..67402)
                     /locus_tag="U2R59_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964613.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(67405..69120)
                     /locus_tag="U2R59_000184"
     CDS             complement(67405..69120)
                     /locus_tag="U2R59_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964614.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(69899..70123)
                     /locus_tag="U2R59_000185"
     CDS             complement(69899..70123)
                     /locus_tag="U2R59_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964615.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            70314..73091
                     /locus_tag="U2R59_000186"
     CDS             70314..73091
                     /locus_tag="U2R59_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8964616.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            73172..73591
                     /locus_tag="U2R59_000187"
     CDS             73172..73591
                     /locus_tag="U2R59_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEM8964617.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            73603..74073
                     /locus_tag="U2R59_000188"
     CDS             73603..74073
                     /locus_tag="U2R59_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8964618.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            74090..74869
                     /locus_tag="U2R59_000189"
     CDS             74090..74869
                     /locus_tag="U2R59_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8964619.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            74856..75677
                     /locus_tag="U2R59_000190"
     CDS             74856..75677
                     /locus_tag="U2R59_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8964620.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            75694..76743
                     /locus_tag="U2R59_000191"
     CDS             75694..76743
                     /locus_tag="U2R59_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8964621.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            76756..77760
                     /locus_tag="U2R59_000192"
     CDS             76756..77760
                     /locus_tag="U2R59_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8964622.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            78393..79412
                     /locus_tag="U2R59_000193"
     CDS             78393..79412
                     /locus_tag="U2R59_000193"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEM8964623.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            79455..80336
                     /gene="galU"
                     /locus_tag="U2R59_000194"
     CDS             79455..80336
                     /gene="galU"
                     /locus_tag="U2R59_000194"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEM8964624.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            80636..81013
                     /locus_tag="U2R59_000195"
     CDS             80636..81013
                     /locus_tag="U2R59_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964625.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            81619..82233
                     /locus_tag="U2R59_000196"
     CDS             81619..82233
                     /locus_tag="U2R59_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8964626.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            83006..84745
                     /gene="yfcC"
                     /locus_tag="U2R59_000197"
     CDS             83006..84745
                     /gene="yfcC"
                     /locus_tag="U2R59_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HEM8964627.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            84902..86086
                     /gene="iadA"
                     /locus_tag="U2R59_000198"
     CDS             84902..86086
                     /gene="iadA"
                     /locus_tag="U2R59_000198"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HEM8964628.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            86197..86400
                     /locus_tag="U2R59_000199"
     CDS             86197..86400
                     /locus_tag="U2R59_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEM8964629.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(86501..87163)
                     /locus_tag="U2R59_000200"
     CDS             complement(86501..87163)
                     /locus_tag="U2R59_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964630.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(87176..88678)
                     /locus_tag="U2R59_000201"
     CDS             complement(87176..88678)
                     /locus_tag="U2R59_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964631.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            89226..90905
                     /locus_tag="U2R59_000202"
     CDS             89226..90905
                     /locus_tag="U2R59_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEM8964632.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            91032..91511
                     /locus_tag="U2R59_000203"
     CDS             91032..91511
                     /locus_tag="U2R59_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEM8964633.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            91730..92410
                     /locus_tag="U2R59_000204"
     CDS             91730..92410
                     /locus_tag="U2R59_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HEM8964634.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            92418..93749
                     /locus_tag="U2R59_000205"
     CDS             92418..93749
                     /locus_tag="U2R59_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8964635.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            93764..94726
                     /locus_tag="U2R59_000206"
     CDS             93764..94726
                     /locus_tag="U2R59_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEM8964636.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            94837..95175
                     /locus_tag="U2R59_000207"
     CDS             94837..95175
                     /locus_tag="U2R59_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEM8964637.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            95254..95961
                     /locus_tag="U2R59_000208"
     CDS             95254..95961
                     /locus_tag="U2R59_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HEM8964638.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(96064..97545)
                     /locus_tag="U2R59_000209"
     CDS             complement(96064..97545)
                     /locus_tag="U2R59_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964639.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            97854..98390
                     /locus_tag="U2R59_000210"
     CDS             97854..98390
                     /locus_tag="U2R59_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8964640.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            98468..99838
                     /locus_tag="U2R59_000211"
     CDS             98468..99838
                     /locus_tag="U2R59_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HEM8964641.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            99905..100240
                     /locus_tag="U2R59_000212"
     CDS             99905..100240
                     /locus_tag="U2R59_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964642.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(100321..101178)
                     /locus_tag="U2R59_000213"
     CDS             complement(100321..101178)
                     /locus_tag="U2R59_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964643.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            101285..101800
                     /gene="tadA"
                     /locus_tag="U2R59_000214"
     CDS             101285..101800
                     /gene="tadA"
                     /locus_tag="U2R59_000214"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HEM8964644.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            101823..101907
                     /gene="ffs"
                     /locus_tag="U2R59_000215"
     ncRNA           101823..101907
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="U2R59_000215"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            102117..103502
                     /locus_tag="U2R59_000216"
     CDS             102117..103502
                     /locus_tag="U2R59_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEM8964645.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            103539..104216
                     /locus_tag="U2R59_000217"
     CDS             103539..104216
                     /locus_tag="U2R59_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEM8964646.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            104224..104988
                     /locus_tag="U2R59_000218"
     CDS             104224..104988
                     /locus_tag="U2R59_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEM8964647.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            104990..105649
                     /locus_tag="U2R59_000219"
     CDS             104990..105649
                     /locus_tag="U2R59_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEM8964648.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(105679..106188)
                     /locus_tag="U2R59_000220"
     CDS             complement(105679..106188)
                     /locus_tag="U2R59_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEM8964649.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(106300..107298)
                     /locus_tag="U2R59_000221"
     CDS             complement(106300..107298)
                     /locus_tag="U2R59_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8964650.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
BASE COUNT        35796 a        18496 c        22095 g        31095 t
ORIGIN      
        1 ttactactcg aaactaagcg actttttcac aacctcttcc ttaaacggtg ttcaaaagct
       61 tgcatctgcg gtaataagcc caaccaaacg aaaaatagga ggagctattt ttgtttggct
      121 gttcttatta cttgatgcag aacagctttt tcacaacctc tttttataag agtttttact
      181 cattaattta caaaaaacaa gcaaaatgcg aattttctca catttttttt aacaaaatca
      241 aagttattgc ttgaaagaag aagaatccat cgttaaaata aagcttgacg tagaggggag
      301 caagaaatat gaaagatttt caattggggg ctgccaccta tttaaaaagt gtagccattc
      361 gggtgaaaga ccgagataaa atgattaatt tttacaagaa cgttgttggc tttgatttga
      421 aaagagaaga aaacgaatta gccattttag gaacagaaga agctggaagt gaaatgttgc
      481 tgctggaaga aagtcctaga gcgaatgatc acatgggggt gatcaaaaag ctgaaccgtt
      541 tttcattgat tatccctagc acagaagaaa tggcagatat cctttgtcgt atccgtaaaa
      601 tgaattatcc aatcaaagaa gctttagaag atcatggacg tatggggatt ttgctcgtag
      661 acccagaaga gaatgaattg gaaatttacc atgaagagaa taagaacgac caaagagaaa
      721 ttccagaaac aatggatcaa gaagcattat taagaaaatc tgaagaaaaa ttcagtaaac
      781 tatcaacagg ttcttatttt gaaaaaatcc atttaaatgt tactaactta acaaaagaac
      841 gccaatttct taatcatgta cttggtttga aggtacataa tgaagaagag ggcatccatg
      901 tattgaatga aggagatttc catgttggtt tgacagaagc tagcggaggc gcaattgatt
      961 tgcctacaga tgaagtgatt ggacttgatt ttctgaaatt catgatcgat actgaaagca
     1021 tggaaggact gattgctcac ttgcagcaac tatcagttga tttcttctta gacaaaaagc
     1081 acacagtact cacaatctat gatgctatag gaatcgaatg gtggttcgtc agtgagccaa
     1141 aagaaaagaa taaaactgac attcgatgcg acgcttaact ttttctttct taacgattgt
     1201 cgcatgtctc gtcattttat gaacggtcat actatcgctt attctagaga tagaaagaga
     1261 aaatagtata ccgggggaaa ctgcgcggtt tttcgcgcag tttttttgtg taaaaaaggt
     1321 tgattcctca tagattaagc tttaagcttg gactgtaaga atctgataga aaagcaggag
     1381 aaaaagatgt atccacacac gaaacagctt attttgaaaa agatggaaga aggattttat
     1441 ccaggtgtag cagtcgcctt cataaaagaa aatcaagtag aaacatttac agccggcttt
     1501 gcccaagtcg ttcctgaaaa gcagctgatg acagaagatc tgttgtttga tgcagcctca
     1561 ctgacgaaag tcgttgcaac cacttcatta gttttacgtc tattagaaga tggaaagata
     1621 gaactcgatc aaccgcttca taaatatctt cctgaatttg aaaatcagac aatcactttg
     1681 cgtcatttac tgacacatac ttctgatatc aaaacatgga taccaaacag agataagcta
     1741 tctcaggaag aattgatcgc cgcttatttg aagctagaac caggtgagca actaggaaaa
     1801 gaagtaaaat atacagatgc cggtacgatt cttcttgggt tgatgctaga ggaaatttac
     1861 caagaaactg cagtggaaat ctttcaagaa caagtattgg aaccattagg aatgatgaac
     1921 agcttatttc ttccttttcc ttccaaaaaa atcgttccca cagaacaact gccttcgggt
     1981 gaggttttgc gtggacaaac tcatgatccg aaagcaagag ttttggctga acatgcaggt
     2041 aacgcgggtc tctttattga tttgaaagac agcattactt ttgtccaaat gtatttgaac
     2101 aagggaaaaa tccgtaatgg tcgtttttta gaagaagaga cgattgattc tttactgcaa
     2161 gatcaaacac cgaaaaaaaa tggctatcgt tctttaggat gggacttaaa aaaggatgta
     2221 gaagacggtc atgcgattct ttttcatact ggttatacag gtacgttttt cttgattgat
     2281 ataaaaacac aagaagcgtt gatatttttg tcaaatcgcg tacatcctgt cgatcatcgt
     2341 gcggagtatc tcatatgtcg agatgaaatt gttgaaaact ttttgaaaga gaaagcggta
     2401 ttaccgaaat aatgctataa tagctatgaa aaatgagagg agtttgaatt atgcaggaac
     2461 ctatgttttt aaaaccagtt tttcaagaaa aaatttgggg aggaagtcgt ttacgttcag
     2521 tctttggttt tgatatccct aacgataaaa tcggagaaga ttgggcgatc agtgcgcatc
     2581 ctcatggtgt cagtgtagta gaaaatggcg aattcaaagg gaaaagatta gatgaactat
     2641 ggtcagaaca caaggaattg tttggccatc cttcagaacc agtgtttcca ttattgatca
     2701 agatcttaga cgcagaagat gatctatctg tacaagtaca tccagatgat gcctatggga
     2761 tgaaacatga aggtgaatta ggaaaaactg aatgctggta tatcatcgat gctgaacctg
     2821 gtgcagaaat catctatggt catcatgcaa agacaagaga agaactagct gagatgatca
     2881 aagatgggcg ctgggatgac cttttgaaga aagtaccagt taaaaaaggt gatttctttt
     2941 atgtaccaag cggaacgatc catgctattg gtaaaggaat catgatttta gaaacacagc
     3001 aaagttctga cacgacttac cgcgtgtatg actacgacag aaaagatgcg caaggacaaa
     3061 caagagagct gcatatccaa caatcgatcg atgtaacaac tgtccctgcg aaaacaccag
     3121 aattacaaat caaagaagtc cgaaaaggga attcatcgat cgtcacttat ttagaaactg
     3181 agtttttcaa tgtatatgag tgggatatta aaggaatcac atctttcaaa aaacaagccc
     3241 cttatacatt gatgacggta atcgaaggag caggagacct tgtcgttgac ggaaaaacat
     3301 atccattaga aaaaggaaca agctgtatta ttccaaatgg cgtttctgag tgggcggtcc
     3361 aaggtgaact agcaatcatt gcgtctgaac caggcaaata gttcccagat agctgaaagc
     3421 agcagacggt ttttcgtttg ctgctttttc tacataaaat ccgtccatca ataaatagaa
     3481 gtctggtgaa aaagatggaa tacaaatgga aagcaaacaa cagcagtcgc gtgtctatga
     3541 aacaactgag aaaagctgga catcacttaa atgaaatgat catgccaaat ctaagtctgt
     3601 ttatcgcttg gggaatcttg tcattagcaa caaaaggtgt gtctggcgat ttgcacacca
     3661 cattagaaga ggtatgccat tggatgatcc agctgctttt acccatcttg atcagttatt
     3721 caggcgggaa atcggtaggg ggacaaaaag gggcagtcgc cggtgcaatt gcttctttag
     3781 ggttgatcgc tcgttccaat gctccacaaa tcgtaggagc gatgattatc gggccgcttg
     3841 ccggcatcgt atatgaacaa tttgtttcta gattccatgt gaaattcaag gctggatatg
     3901 aaatgcttgt cagcaaccta ctagtaggac tgactggtag cgttatttgt ataattggaa
     3961 tcgtttttat tgaaccagtt ttaaatagtg ttcacttgtt gctcgcctcc gttgtgtctt
     4021 ggctagtcac aatgaatctg ttaccacttg tcagtctgat cttagaacct ctaaaagtac
     4081 tatttttcaa taatgcaatc aatcatggtg tattgacacc tttaggaatc gaattctcac
     4141 aaacagtcgg gtactcttcc ttatttttga tggaggcaaa tcctggacct ggtttaggga
     4201 tcttactttc tatcctttgt tttgcagaaa aacaggaaaa agtaaatgcg agtggagcat
     4261 tgatgatcca tgcgattggc gggattcacg aaatctattt tccatttgtc ttgctgcgac
     4321 cgtatctatt tttagctgta atggctggtg gggcaagcgg cacgttgata tttcaatggt
     4381 tagatacggg attagctgca cctgtatcgc ctgggtcact actcgtgatt tttgccaatg
     4441 cgccttatcc acaactagct ggggtaagta tagggatagc aatcagtaca tttgtgacct
     4501 tcatttgtgc agcgatacta ttgaaattac caaataaaga aaaagagaac aaaacggtca
     4561 aagaaagggg agaaatcttg gaaccatcta tcattcattc cgtcattttt gcttgcgact
     4621 caggtatggg atcaagtgct atgggagccg ccctgctgaa aaagaaatta gcagcagaaa
     4681 aaatcgatct ttctgtcgga tacagctcta tctatgaatt gaataaccaa gtaaatcagc
     4741 tggttatcgt gcaacatgaa ctagcgggtc ttgcaagaga aaaagtacct caaagtcaaa
     4801 tctatgtact ggatcacttt ttggaaacag atatcttgct gtcacgaata aaagaagcga
     4861 tccaatttcc aaagcgggaa gaaaaaaaag agatagcaga tatcacagaa caaaaaacgt
     4921 cgcctgctaa tattgtattt ttgtataaaa acaacagacg cggctcacaa actatgggca
     4981 tgacgatttt aagtcaatta gcaaaaaaag cgaaaaaaca gtttgttatc tcaaaagaat
     5041 caatagaaaa aatcaaaatc caagaagaaa cgatttatat cgcacaaaga gaactagctg
     5101 taactgaaca gctagaagaa aagatccctc ggctagttct agttgaacat tgggtagcta
     5161 cgaatgaata cgaaaaactc gtgaagggag aaatataaga tgtatttatc gcccagagaa
     5221 aaacaattat tagcagaatt tctcagtagc ccgtcacctg tatctatcca aaaaatgatg
     5281 aatttattga aggtcagtaa acggactatt taccgcgaat tagataatct tgaagtctca
     5341 ttgaaatcgg taaatgcttc tttgaaaaaa gcagctagag gctcatttgt cattgaggca
     5401 tcagaagaag tattagagca attaaaagaa aatacagatg ggaaaagtaa tgacttatcc
     5461 actgctaaac gacaacacgc gattttagcc gagttgttac tgacgacaga gccgttgagt
     5521 cttgctcatt tcatggaatc atatcgcatc agtaatacca ctttttatgc agatatcaaa
     5581 cagttggaag aaagtattcg ccaactgcct ttggaaatca ttcggaacca gggatacgag
     5641 atcgaaggac cggaaaaata ccgccggctt ctgacagcga atgtattaga attagaaatc
     5701 aatgaatatg aactttttca tagtatttct ttcgatgcat cactgaatta tttttttcga
     5761 ttcgttgatc cgcaacatct atctcttgca cgcaaagtaa tcggggaaga attgatccaa
     5821 aaaaagacca atctaagtga tagaaagctt gaacatttgg ttttgatgct gacattgacg
     5881 atggagcgtg tgacgaaaaa tcatttactg acaaatgaga catataatag tctggcaaac
     5941 aaagaattac tacagacagc taaacgattg ttttcacgga tcgcttctga gacaaaacaa
     6001 ctttatccag taaatgagat cgtctttttt gcaggattat taaatgactt cacgaactca
     6061 tttgatcaga atttctttga agagacgttc gatacacagc ttgcttattt agtaaaacaa
     6121 ctgattcaag aagtaagtga agagacgaat gtccattttt atgaagatga aactttgtac
     6181 aaaatgctgt tgactcattt atctggtgtg ttttcaagag ccgttttaca agaagagaca
     6241 ctgaccaatc cgattttaga aaaaatcatg gttcaatacg aggaagttgc gaatgcaatc
     6301 cgtaaagcag tagagcggat ttttcaagaa aaaaaattat ccgaagaaga gatcgcttat
     6361 atggtccttc attttgcgaa ttcattggaa cgaagtccga aagaaagcaa tatcagtatt
     6421 gcaggatttt cgccaagtgg attagcttct actagcatgt tggaactacg attgaaaagg
     6481 tattttccct tcatccaaca aattcatttc tatcggattg ctgatttaaa aaaaatcgat
     6541 ttacaagaag aatatgatgt tgttatttct acatctattt taccaggata cggtggaaaa
     6601 tatattttag tctccccgct actgctagaa gatgaagtca agcagctaaa agaagctttt
     6661 tcgcatattg agaagaaaaa aaggcaaaaa attacgtata acagcaataa cgagtggatg
     6721 atagaagata cttatgagga aacaatgcat ttcatggatc aaatcaatca attactcggt
     6781 cgttttttta tccaagaact ggataatcct gagacgattt ccgaaacgat tcgcagctta
     6841 tttccttatt ttcctgaagg actagtaacg gatgaagagg tggttcatcg ccggctgctt
     6901 aagcgatatg aacaagcacc tatcggtatt cctcatacaa atatggggtt attccataca
     6961 tccagctcat tgatttctaa accgatcttt tgtattttca atttgaaaca tccgttgacc
     7021 attgaaggga tggatagaca gccagtcgat ttgtcccgta tgttagttat gctggcgcct
     7081 tcgccaatcc aagaaaaaga cgggattctt ttaggaaaga tcagtggagc aatcatcatg
     7141 aatgacttga acaccgagat cttccgctca ggaaataaag aaatcgttta tcagttgtta
     7201 gcgaaaatcc tgattgaaga aataaagaaa tgaaggtgaa aagatgatac agctaccagc
     7261 agaaaaaata ttgctcgatc aatcctatca aaattggaaa gaagcgttga ccgagatcgg
     7321 ccagtggatg acccaacaag ggggaatcaa accggcatat atccaatcaa tgatcgaaag
     7381 acaagaaaaa gcgagtgtct atatcgggaa tttcgtagcc ttgccacatg ggactgacaa
     7441 agatgaagaa gtagtagaag aaggaatcta tttagtccaa gtgcctgatg gtgtggactt
     7501 tggaacaaaa gaggaaccaa aaatcgcgac actcttattt gtagtggctt taaaaaaaga
     7561 acatcagtta gcggtgctcc aagatttagc ctttttctgt tcagacatcg accaagtaat
     7621 ggcgctcagt gatgcggaaa ccattgaaga agtccaaatg atttttgaac atggacatat
     7681 ataaccaatg ttcacagtaa aaaaagctgc cttgcatcaa gtaataactt caaccaagat
     7741 aaaaataaga ggagctattt ttgttgggag gttcttatta ctgcggatgc aagcttttga
     7801 aaactattta ttctagaaaa ccgtttattt gaaatagggg acggtgacaa ggtttttgtc
     7861 accgccccta ttatttttgt gttttaatag ctctttttta tatagatagt gcccatacct
     7921 atgaataata aaacgatact ccatatacca agtgtcaaga taccattcat gaaagtaacc
     7981 tgttctgaag ctagtggcga gaaaatatct cctcctatga tcacattttg aaaatcaaca
     8041 taagaagttg gcaagtaatg actgattgat tctatccatc caatcgaaga aaacaagcga
     8101 tactctgcta agaaaagaca aagaagtgta cctaaaagat tgactagaga atgttcaaat
     8161 aaagcagata gaagaaaact gattgtactt aaaaagagca cccacaacaa caggaacaga
     8221 aagctctgga aaagatactc atacatcggc aggattcgta tctcctgacc aatgatcgtt
     8281 cctacaggat aacggaagtc tcccaaacca tttttgatta ttactagtat agagacgatc
     8341 aaaaatggca tcacgagact tagcatagct gcaccataat aaatggtaaa acggatgcta
     8401 tgtttcttta ccatactatc cagtaataga ttgactagag agattacctg ctttcttttt
     8461 tcataagaga tgatggaaga aagaaacaag gcggttatac ataaaatcaa aaaactagaa
     8521 atcattcctg aaaaaatatt ttcgtagtaa tttgctaaag agagatgcgc tggcaagtca
     8581 aaaatagaat atctttggat ctgatgttct ttcatataac ggagcaactc gacacgtttt
     8641 tgttgttcaa tgattggaat tccttgtctt tgaccagaaa tcagtcgatc cagtatatct
     8701 ttttcataat gataagttgc ttcgaccatt tgctggacat tccctgtgtt ttttgcatgt
     8761 aagattgctt cgatcagttt gttgcttttc tctaaacttt ccacaaattc tttctcattc
     8821 tcatcttctt tcaacgtttc aatcaaacgt tgcatctctt catagttatg attcagttca
     8881 tcgaattctg tataagcaag tttatgatca aaaaaaagtg ggaatgcaaa gagcacgacc
     8941 aacaatagag gaaataaaaa gtttactttg ttttttagta agagattgcg ttcaaatgta
     9001 agtaaagaca tagttacacc tcatataatt tacgataaat agctaaaatc tcttccatat
     9061 ttgaggattc tgtgacgatt tctccatttt ttagaaaaca tgctttagaa caaatcgatt
     9121 ggatattcgc gatagcgtgg gaagaaagaa gaatcgtctt cccctctttc tgccattgtc
     9181 tgatgaggct attcaagata tcaatacttc ctgggtctaa tccgttcaac ggttcatcga
     9241 ataacatgac agatgaatca ctgatcaagt aagcagcaag caagacatgt tgtttcattc
     9301 ctagagacat ttttccaatc ggcaaagtaa ggtactcagt catcttcaat cgttggaaaa
     9361 cagtttggca ttctactttg ctctgccaat agtatttgat caaagtcaaa taatcaacag
     9421 ccgatagata gtcggataac tgattcgttg attctagaaa aaagaaagac cggcgataat
     9481 ctgtataagc agtaggagag atgttgtgaa gggacaattg atcataagtt gttggcagca
     9541 gttgggcaat gccattcagc aaagttgttt tgccaaatcc gttcggggca atcaaagcag
     9601 ctacttctcc tgattctact aaaagattca attgtcgaat cacacgtttt ttaccacgtt
     9661 tcatgttcat gtttttgatc agtaatgtca tagataggcc tccaatataa aatttaataa
     9721 cataatagaa tggaaaacat ctaaattaaa tgctaacaaa agttattgtt tgcatattat
     9781 aaaaaaatta aaataacagt tttatttaaa attgaagttt tctgataccg aaatcttttt
     9841 attttgctga catactcaaa cctttggcac aaagtttcgt gccaaagtac gactatttct
     9901 ctttttagta agcggataca attagagtat caaaaggaga gagggagaga caaaatggaa
     9961 cggacgattc ccaaaaacaa catttcgcta aaagcgaggg tacaaaaatt aggcagtact
    10021 ttatcaagca tggtcatgcc aaatattgga gcactgattg cctggggtgt attaacggct
    10081 ctatttatcc cagatggtta tttaccaaat gaggctttcg ctaccatggt aagcccaatg
    10141 ctaacttatc tgattccttt attgatcggt tatactggcg gaaaagtaat tgctggtgac
    10201 cgcggatcag ttgttggggc aattgcaacg atgggtgtga ttgtcggaac agatattcca
    10261 atgatgctag gcgcgatgat catgggacct cttggtggat atgccatcaa gaaatttgat
    10321 cagctattcc aaaaacggat caaatccggt tttgaaatgc tagtcaataa tttttcagca
    10381 ggtcttatcg gttttggatt agcgttatta ggtttttctg cgattggtcc agttgtcgat
    10441 gcattgactc aagcaatggc aaaaggtgta gagatcattt tatctgccca tttgattcca
    10501 ttgacaagta tttttattga accagcaaaa atcttatttt tgaataatgc aatcaatcat
    10561 gggattttga caccattggg aactgaacaa gtagcagagg ctggaaaatc tattctattc
    10621 ttgcttgaag caaatcctgg tccaggactt ggcgtattac ttgcttttac tttgtttggc
    10681 aaaggagcag caaaatcttc agcaccagga gccatgatca ttcacttttt aggcgggatc
    10741 catgaaatct attttcctta cgttatgatg aaaccgttat tattcttatc agttataggc
    10801 ggaggaatgt caggaagttt cattttccaa ttgatggatg ctggactaag agcgccagct
    10861 tctccagggt cgatcattgc gattctagcg atgacaccgt tcaattctta ccttcctgtt
    10921 attttgggcg tgattgttgc cgcagctgtt tcgtttggta tttctgcagt aattttgaaa
    10981 gcggatgcga aagatacaaa tgaagacttc gaaaaatctg ttcaagagac aaaggcagct
    11041 aagcaagctt ccaaaggtgc ccaaggtatt cctcaaggag ctacattctc tggcgtacaa
    11101 aaaatcattt ttgcttgtga tgcaggaatg ggatcaagtg cgatgggcgc ttcgatcttg
    11161 agaaaaaaag tacaggaagc agacttgcct caaacggtga ccaatcaagc aatcagccaa
    11221 ctgacagatg actcgaatac attgatcgtt actcaggtcg aactacaaga aagagcaaaa
    11281 caaaaagcac cgagcgcgcg ttttgtctca gtagaaaact ttttgaattc acctcgatat
    11341 gatgaaatca ttcaagaatt aagcagcaag cagaaaacat cagtttctga aattgagaat
    11401 gagccagcag aagagtttct ttcagcaaac atcaaacaaa tcaaagagat tctacttgtc
    11461 cacgatgatc gttccggatc agcaacaatg gggatgaccg tgctcaaaga tatattagac
    11521 aagaaccatt taactatccc gttaagaaaa gtcaatatcc aagatttaaa agatgaacct
    11581 gattcactga tcgtagccaa agaaagttta gcggaaaaag tacagatggc tgcacctcaa
    11641 tccattcatt tatcagtcaa cagcatggtc aatccgcaaa aatacgaatc gattgcacaa
    11701 tatttgaaac agacagctta agggaggaaa acagcatgca aagtttgcca ttcgacatga
    11761 tcgagctcaa tcgatctttt aaaaccaaag aagaagcgat ccgctattgc ggtcagatgc
    11821 ttgtagaagc agggtgcgtt gatgaggaat atatcgatgc catggtagat agagacaaaa
    11881 tgttatctgt ttatatgggg aattttatcg cgattcctca tggaacagat gaagcaaaaa
    11941 aatatgtgaa aaaatccggc atctgtgtcg ttcaagtacc agatggtgta gattttggta
    12001 ccgaagaaga agaaaagatt gcgactgttt tgttcggtat tgcaggagtc ggagatgagc
    12061 atttgcaact tgtacagcaa atcgcacttt attgcagtga tatggacaat gttgtccagc
    12121 tagcagacgc gctcagcaaa gaagaagtaa cggaaaatct agcaattgct taaggagaga
    12181 gaaaaatgag agcagtacat tttggtgcag gaaatatcgg tcgaggattt attggagagg
    12241 ttttggcagc taatggattt gagattactt tcgtagatgt gaatcacacg atcattgatg
    12301 ctttaaatga aagaaaagaa tacgaaatcg aattagcaga tgaatcaaaa gaaaaaatca
    12361 ctgtaaaaaa tgtcaaagga atcaacaatc aaacaaatcc agaaaaagta atccaagaaa
    12421 tcgctgaagc agatttagtt actaccgcca ttggcccgaa tatcttacct tttattgctg
    12481 agttgattgc aaaaggtatc caagaaagag aaaaggaagg aagcacaaca tctttagata
    12541 tcattgcctg tgaaaatatg attggcggtt cagcatttct agaaaaagaa gtgtataaat
    12601 atcttccgga aacatcattt actgacaaat atatcggctt tccaaatgca gcagtcgatc
    12661 gaatcgtccc attacaacac catgaagatc ctttattcgt ccaagtggaa cctttcaaag
    12721 aatgggtcat tgacgatagc caaagaaaaa ataaaaaaat ccaattaaaa ggggttttat
    12781 atgtagatga tctagaacca tatatcgaac gcaaactatt tagtgtcaat actggtcatg
    12841 cgactgtcgc ttatacaggt gccttgttag gttaccagac cattgatgaa gcaatgcaag
    12901 atgcgttagt tgtggcacaa ttaaaatcag ttttgcagga aacaggaagt ttgctgattg
    12961 ccaaatgggg gtttgatgca gagcagcatc atgcgtatat tgaaaaaatc attcatcgct
    13021 tccaaaacaa aaatatctct gatgcgatca cacgtgtcgc tcggacacca ttacgtaagt
    13081 taggttatca agaaagattt acacgtccag tgagagaact acaagaacat aacttgactt
    13141 gcccacattt gacggcaaca atggggatta tttttaatta ctatgatcct gaagatgaac
    13201 aaagccgtca attgcatgaa atgaagatcc atgaaaactt ggaacaattg attcaagaag
    13261 tcacaggaat caatgatccg aaaacaatcg ggaatatcaa gcaaaacgtg aaccgttatg
    13321 ccaagcaagt cgcttaaaat aggatacgaa aaaggggaat gtgacgaaat ttttgtcaca
    13381 ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat ccaattcttt
    13441 accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct catttcttgc
    13501 aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac cttcagattg
    13561 gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt caccttcacc
    13621 taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga attcttcgtt
    13681 atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt agtgatccag
    13741 tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac ctagcaattg
    13801 gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga tcaaagaatc
    13861 tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac caccgccaaa
    13921 gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga tctccgtatg
    13981 gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc cgttatcacc
    14041 atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat tagccacggt
    14101 tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc aatacagcag
    14161 tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt tcgattactt
    14221 ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact tttagacgta
    14281 aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc atatcggcaa
    14341 agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg taattggcat
    14401 ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg attacttgat
    14461 tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg atattgatga
    14521 cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt ttatcaggat
    14581 cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca ttatacatac
    14641 cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac acattgtcca
    14701 tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca caatttggac
    14761 agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg tgatgacaat
    14821 ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct tcttcatggt
    14881 caaagccata atattttcta ggattgactg tttcgataga attgaagatt ggtgaatcac
    14941 cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc attttatagg
    15001 tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta aataagaaca
    15061 gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt tctaggacag
    15121 caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca attccctgta
    15181 ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc aaaatattga
    15241 ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg acttggtagt
    15301 cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta cctggtaaac
    15361 ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca actgcaatcg
    15421 caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga cgaataaatt
    15481 caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt cttaagaaaa
    15541 ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa aaaaacagct
    15601 tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta cctatattcc
    15661 cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct cgtgtttctt
    15721 ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac atcagtgtag
    15781 caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat aaaccagttg
    15841 ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct tctgtagcag
    15901 ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca acgactgatt
    15961 ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct tcacttttga
    16021 ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc ccgccgccta
    16081 cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt gttgtgattt
    16141 gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc gaataaaaca
    16201 tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc ttttccaata
    16261 gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca gctaatttgg
    16321 taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat agccattccc
    16381 ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac atgatcagga
    16441 tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg tcaaacccag
    16501 agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca cgccaacgat
    16561 caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt aattgaaacc
    16621 agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa cgcggttgat
    16681 tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta gaaaaaatga
    16741 caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat atttccagca
    16801 gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt ccagtcacac
    16861 tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta tctggttcgc
    16921 gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata taataaaaaa
    16981 cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc cgctgcagcc
    17041 ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg tttctaccag
    17101 tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa tacagctttc
    17161 gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg aggaggaata
    17221 acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa ataaattatg
    17281 atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag cctaagatat
    17341 taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg tctcaatatg
    17401 cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag tatttgcgaa
    17461 gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac catcatgttg
    17521 cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta acaaaccatc
    17581 ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg cgattagatc
    17641 ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc ctgaccatct
    17701 cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa aagatttacg
    17761 ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc tctttgcaaa
    17821 tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc gctgccaagc
    17881 agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta aaaacatcaa
    17941 ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa aaaataaaga
    18001 atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa ggaaacaaga
    18061 ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt gaagccaatc
    18121 gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa tagttccagc
    18181 taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac tacttcagtc
    18241 tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac aagtacatgg
    18301 gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag ctcaagcgaa
    18361 acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag tacaagtccg
    18421 gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga taacacgcaa
    18481 aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac ccaaacgtat
    18541 aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac ggggtgcata
    18601 aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat acgattttaa
    18661 gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa aaccaaaact
    18721 atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt actgttttaa
    18781 atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag ctttttgtga
    18841 agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat aatggaaatt
    18901 cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat tatcaattga
    18961 aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca aatgaactcg
    19021 gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac tatgtcaaga
    19081 aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac atggaaaaag
    19141 tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga ttgttcatcg
    19201 tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt ctgaaattga
    19261 ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc caaagaagaa
    19321 gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac gtttattcgg
    19381 aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg agaaagataa
    19441 gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata aagaaagtac
    19501 aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag gaggtaagct
    19561 gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc tattttatta
    19621 gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga ccctacatta
    19681 agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat ggatattatt
    19741 actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat cggtatgcct
    19801 ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa gtatgatgaa
    19861 ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg agaatatgct
    19921 tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag tgactttgaa
    19981 tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat ttcaaaagac
    20041 agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt tttccgttat
    20101 tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct gtgacatgtt
    20161 ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg ctcacttttt
    20221 ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg tttttgttca
    20281 taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag cccgtttttt
    20341 ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga tgactaattt
    20401 gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa atttcataaa
    20461 gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat agaaggatga
    20521 gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt cggacatttt
    20581 tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct gaagcatcgg
    20641 caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca gttccgcctc
    20701 cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt agttcttcgc
    20761 gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg atggaatcaa
    20821 aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta acttattata
    20881 gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat ctagaaagaa
    20941 tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc gagaaatatt
    21001 actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata tcgaggaatc
    21061 aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct ttatcactct
    21121 ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat aaaaaaagac
    21181 tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta cgcagcaaaa
    21241 cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat atatgatcaa
    21301 actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc aaatttatgg
    21361 gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg agcaatagat
    21421 ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa aatcaagtat
    21481 aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt ttttaagtat
    21541 ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa ttatgaagaa
    21601 caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg tttaggcgtt
    21661 gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga aacagacgta
    21721 tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga tgaagcgcaa
    21781 ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt ggatattccg
    21841 gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg atcaaaatat
    21901 ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt ctgccacaaa
    21961 aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg cgatcaagtg
    22021 caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt tcacccatca
    22081 atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa gaccgttatg
    22141 aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag cgttttatgc
    22201 agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt cgttataaag
    22261 aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg gatgatgaaa
    22321 tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa gtcttagaag
    22381 aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat atcatcatgg
    22441 aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat cttttcaata
    22501 tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa gctaacgtta
    22561 ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac gtatattcga
    22621 aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact gaatcgcaag
    22681 ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa gaagtagaga
    22741 tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt gctggcggac
    22801 agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca gggatcgttg
    22861 ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg aaaatcttgc
    22921 gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat gccaatcgaa
    22981 aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat ttcccgcaaa
    23041 atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag attttagcag
    23101 ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca aaactggaag
    23161 ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc ttctttttta
    23221 gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg aaaacaatgg
    23281 aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga acagcggttg
    23341 atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt gctaggatat
    23401 gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc tcgaccagaa
    23461 acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt agaagtgata
    23521 gatattggga cagggactgg agcaattgct attagtttga aagcagcaag aaaaaattgg
    23581 catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga aaatgctcag
    23641 aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt aatggatcag
    23701 caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg ggaactgatg
    23761 gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa cgatggatta
    23821 gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa tggaaagatt
    23881 tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca gcaagcattt
    23941 ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat gatccaagtt
    24001 tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa aaaaacactt
    24061 atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac tattgacaaa
    24121 tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata agaatgtatg
    24181 aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag aattgcaaga
    24241 ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa cagtatacgg
    24301 attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg taaaagggag
    24361 accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa aagagtatgt
    24421 ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg gaccattaac
    24481 tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag gattatccac
    24541 agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac tttccggtgt
    24601 tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga ctgcagatca
    24661 tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag ctacgcgaat
    24721 tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta tgattttacg
    24781 accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg ttgctattga
    24841 tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat acaaacacta
    24901 ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg cagttcaatg
    24961 ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg cggatcaagt
    25021 gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag cggcggctaa
    25081 aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag atttgatttt
    25141 tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct tgaaaaaagc
    25201 agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc ttttagtatg
    25261 atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt aactaatcgt
    25321 aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa aattgtagga
    25381 aaataaaatt gtaggaaaat aaaaaggagc tgttgtttgt ggtagattac aaaacgtttg
    25441 accctgatct ttgggctgcg atcgccaaag aagaagaaag acaagaacat aatttggagc
    25501 tgattgcctc tgaaaacttt gtctccgaag cagtgatggc tgcacaagga agtatcttga
    25561 caaataaata cgcagaaggt tatccagggc atcgctatta tggtgggtgt gaatttgtcg
    25621 atatcgttga aaatttagcg attgaccgtg caaaagaatt attcggagcg aaatttgcga
    25681 acgtccagcc tcactccggc tctcaagcca acacggctgc ttatctcgct ttggtagaac
    25741 caggggacac gatcttagga atggatcttt ccgcaggcgg acatctaaca catggatcac
    25801 cagtcaactt cagtggcaaa acctatcact ttgttgctta cggtgttgat ccgacaacag
    25861 aagttattga ttataatgtg gtacgtattt tagctagaaa acatcaacca aaattgatcg
    25921 tagcaggtgc cagtgcttac ggacgaacga tcgactttgc gaaattcaga gaaatcgcag
    25981 atgaagtagg cgcaaaactg atggtagata tggcacatat cgcaggatta gtagcagcag
    26041 gacttcatcc taatccagtt ccttatgcag atatcacaac gactaccact cataaaacat
    26101 tgcgtggccc tcgaggcggc atgattttga caaacgatga agcattagca aaaaaaataa
    26161 atagtgcggt atttcctggt attcaaggcg gccctctaga gcatgtgatt gcgggtaaag
    26221 cagtagcatt caaagaagca ttagatcctg catttaaaga atatagtgaa caaatcatcg
    26281 ccaatgcaaa agcaatggtc aaagttttca atcaagcaat tggaaccaga gtcatttcag
    26341 gggcgacaga taatcatctg atgttgatcg atgttcgcga gttaggtata aatggaaaag
    26401 aagcagagag cattttggac agtgtgaata tcactgtaaa taaaaactcg attccttttg
    26461 aaacactaag tccattcaaa acaagcggta ttcgaatcgg cacgccagca atcactactc
    26521 gcgggttcaa agaagaagat gctgtaaaag tggctgaact agttgtcaaa gcattacaag
    26581 caaaagatga taacgctcaa ctagacgaag tcaaaacagg tgtacgcgaa ttaactgaaa
    26641 aatttccgtt gcataaaaaa taaaaattta aattccatta gtaaacagaa aagttcaatg
    26701 ttgggctttt ctgtttattt tttgggaaaa cggattcttt gacaatatcg gtgatgctct
    26761 ctagtatatg aggtgtaatt ttagtcttca cactaaatct cagggaggaa aagtcatgac
    26821 tgatcgtatc tcgttagaaa aggaagcagt agcattcagt gatgcaaatg cgcctcatcc
    26881 gcgtatctat gaactagcac cggaagaagg aagagtttta ctagaagaag tacaagaatc
    26941 acctgtgaac aaatattccg tcgatattga agacttgatg gtggatactg gcgaatgggg
    27001 aaaactcaat attcgtctcg tacgaccaga agggaatatg gataaattac cagttatttt
    27061 ttatattcat ggagcaggct gggtttttgg cagtgctcaa acccatgata aattgatcag
    27121 agaacttgcg gttcgtacga attccgtcgt tgtctttcca gaatatagtc gatcaccaga
    27181 agcaaaatat ccaacagcaa ttgaacaaaa ttatgctgtg ttgcaacagc tgaataaatt
    27241 agccaagtca aaaaatctgg atctcgagaa tctaatcgtt gcaggagatt cagtaggtgg
    27301 taacatggct acagtcatga cgatcttaac aaaagaacga aagggcctcc caatatccaa
    27361 gcaattgctg tattatccag tcacaaacgc tgattttgat acagattcct atcatgaatt
    27421 cggagaaaac tattttttga caagagaagg aatgatgtgg ttttgggacc aatatacgac
    27481 gaatgaagaa gagcgtgctg aaatcacagc ttcgcctttg agagcaaata taaatgaact
    27541 aaatgatctt ccttcagcaa tgattttaac gggagaagcg gatgtattaa gagatgaagg
    27601 tgaggcttat gcgcgcaaac ttcgtgatgc aggggttcct gttacacaag tacgcttcca
    27661 aggaatcatc catgattttg tcatggtaaa tgctatggat cagacaaagg caacgcgtgc
    27721 agcaatggca ttatctactt cttggatcaa gaaaaaagaa taagctttgc ttgtccgcag
    27781 gaaaacttct tttcaaaaac ggattttctt aggaaaaatg gcgagtttga ctagtcaatc
    27841 acttgatttt gttttacaat taaaaagaaa cgacagaaca aaggagagct taaaaaatgg
    27901 gcaaatttca agtgatcgat catccattga ttcaacacaa actaactatt attcgggaca
    27961 aaaactgcgg aacaaaggtt tttcgtgaag tagtcgatga aatcgctatg ttgatggcat
    28021 atgaagtatc acgggatatg ccattggaag acatcgtgat cgaaacaccg atcactgaaa
    28081 caacacaaaa aacgttgtct ggtaaaaaag tagcgattat tccaatcttg cgcgcaggta
    28141 ttggaatggt tgacggtatc ttggaattga ttccagctgc taaagtggga catatcggtc
    28201 tttatcgaga tgaagaaaca ttggaaccac atgaatattt cgtcaaactt ccagaagaca
    28261 ttgatgcacg tcagttgttt gtagtagatc caatgttggc aacaggcgga tcagcaatca
    28321 tggcaatcga tgcattgaaa gaacgtggcg cgtcgaacat taaatttgtt tgtttggtag
    28381 cagcacctga gggagtaaaa gctttgcaag aagcgcatcc tgatattgac atctatacag
    28441 cttctctaga tgaaaaattg aatgaacatg gttatatcgt tcctggacta ggggatgcgg
    28501 gtgaccgttt gtttggtaca aaataagtaa atacgaaaaa gggtgtgaca caacttttgt
    28561 cacatccttt tttggtcatt tttaacgttt gatgcagaac agctttttca cagctttcgt
    28621 ttgcatataa aaaaaccatc ccaaaaatgc agagatggtc aaattcaaat cttttttagt
    28681 tctttgtagt taacgattac tacaccctta ctttgcgtca tcaagttcgc attttctgca
    28741 gtttcatcaa tctcaacaac agcggaattt ttcaattgct ttgaaatcgt tccagtttgc
    28801 gacttgccgt gaattgtgaa cattacgtga gtattgatct tgaatttttc accaatttcc
    28861 gatggtacga tagttgtatc aaattttcca aaagttgcca ttttcataaa acctgccttt
    28921 cacatcaatt ataccacgtt ttatgaaaaa tatcatgaaa ttaaactaat tttccatcgg
    28981 actctttaca atcagccaaa tagagtatat aatttctttt ggataaggcc agcttagctc
    29041 agttggtaga gcaacgcact cgtaacgcgt aggtcgtagg ttcgatccct atagctggca
    29101 ttaaaagaga agacagatat atcaaggatt tttaatccat tgatacatct gtctttttgt
    29161 ttaaaggaaa taaagtatgc tttcttagca atagagcatg tattatttct ataaaaattt
    29221 aggagaataa aacgactagc aatatagctg tgaaatcaaa tatcacatga actgcccaac
    29281 ttgtaatgat cgagttgctt ttaatggcag cttggttgaa taacaatctt gccacccctt
    29341 gtatcaaaag gatgtgtgct acagtgtgta aaatatttcc attatcataa gtactgtaat
    29401 ggataaatcc aaagatgatt gctgacaaga aactagcgac aggaatgctg aacttactag
    29461 aaaaaatagc gagaaaatac actgagaaca attcttctcc aagtatcatg ataggcaaaa
    29521 taataaataa taacgggctg aaagcctcat ttattggatt gcctgttaaa ccccatttca
    29581 aaatttgttg caaaaatacc gagactgcgg cactgattac tacattgata aaaaaatatt
    29641 tggctatatt tttgacagga gcgacaggtt tcgagaacat ttttttcgta tcttttttac
    29701 caaaaacaag tgtaaatgct ataaatccag tgatagttaa agaaaaaatg ctaataatgg
    29761 atggcgcaaa tagcaaccct aacaaaccga gtacaacgac aatagtgccc aatatccctt
    29821 ttttaagttc tatttttttt cctaaaatgt tattcatgat aataactcct actattcagt
    29881 ttttgaagat agagtcagta tacatgaaga gttaaaatag gcaatgtttt tttatggata
    29941 tttgtattgc taaaaattta tcttatatat tcattttgat tatactactt ttatttgtaa
    30001 aaattttcta gcaaaaccaa gtgcttgcaa ctgattaagc gtacaatttt ttagatgttc
    30061 cgagcgtact tcaatcattt caaaggagtt gctacttaaa tcgatatttt ttaaatcagt
    30121 atcaaaaaag ctagcatttt ctaaatcatt agtagaaaac attattttag tgagggaaca
    30181 gtctacaaaa tctgcgcttg ataagacaga gtgctcaaag gtactttctt ttatgtttga
    30241 accagataaa tttacatagt ccattttaca attctcgaat aacgtgttcc caatataact
    30301 ttccatcaat ttagtacctg ttaatttaca attgacaaat ttcacgcgat gcaacatgct
    30361 ttttgtcaat atacagcctg aaaaatcaca gttttcgaat atacagtcgg taatctccat
    30421 tctttgaaaa tcattggaag caaaaaatgc atacttgaaa atagatttgt aaataattgg
    30481 atggcagatt atttggtttt cgatgacctc tttttgtgaa aggatattat acagttcaaa
    30541 atcttcgttt tcatagatat gaaaaaagga tcctttattc aagcttgctt cattaacttt
    30601 aggaaaaatc atatttaatt acctccattt tcataaagtc atattaacaa aagctaaacc
    30661 aacttacatt agcagaaaat gagataggtt ttcgcctttt tcgataacga tagtgtcgct
    30721 atctcttgaa acgttcttag aattgccctg agagacacaa attaggcgta attctaataa
    30781 aaatcttaga ataaaaattt ttactgattt aatttagaat gtttttaaaa taaaaatcgt
    30841 tgccataaca gtgtattgaa aggttttaac aatccagtaa tgatttaaaa aaatctagat
    30901 gtagcgtata ctttgtttat agaatgtagt gggaagaaat atatttttgg gaggaaatcg
    30961 tgatgtctaa aagtgaagaa atagaaaaca tggtactaaa attatatgat ctcgttttaa
    31021 atccagagat caaagaaaag gaacgtatac ttttgataga cgcaaagaca ggcttagaaa
    31081 aaggtcagta ttatcctaaa gtcataaata atttggaacg tagtttacgt ccgttagcaa
    31141 tcaggggaga attgtctaaa ccagtatcac cgttttatat ggagatatca acaataggaa
    31201 aatttgaaaa agaattaggt cgaggaatgg cttcggcacc gattactttt gggcatttat
    31261 aaaaacgagt tattcatctc aatgaattaa aaagtatagt caatctcata atgcaggcta
    31321 ggttcattta tttgaacaga gtctgtattt ttttattcta aataaagaaa cagatgtttc
    31381 tttatattgt attttatcct ttaattaaca caaaaacagc tagtataaac taataatgtt
    31441 aattaaaagt gtattttatg aaactatcgt tatttattaa tgttgcattt ttgtaagtta
    31501 aaaattggaa atatagattg aaaaaatgaa agcaataagt aaaataaaat gaatatatgc
    31561 gaaaaaataa tttacattag gaaaaacctt gtaaaaacag ttttttggca tatttatttt
    31621 ttataaatat ttgtaaaata actatcaatt ttttagttaa aagattggaa atgagtgggg
    31681 gaggaattga agaaaggatt tttgagagat gatatagtag gttttatttt tagttaaaat
    31741 aggggagata gaaaaaatga aaaagtgtag aaatattatt ttatcaatgt tatttattat
    31801 tactaatata acatcactga ttcctgttca tgtctatgcg gatgcaggca gagatatcag
    31861 cagtaatgtc acttcgttga ccgtggaccc aacgaatatt acagatggag gaaacataaa
    31921 agtaaaattc tcgtttgacg aaaaaaaaca aaatatccaa ccaggtgatt atctttggat
    31981 caattggcca agtgaaggaa atattcgcgg tgaaggattc caaaaagaaa tcccattaat
    32041 gattgaaaat aaaaatgttg gaactttaac ggtcagaaaa gattctgcgc aggttgtgtt
    32101 taatgaaaat attaaaaacc tagactcagt agaaggttgg gggcaatttg agatacaggc
    32161 cagaaacgta accgataccg gtgaagaaaa tacgggacca ttcaccgtga cgagcggtga
    32221 taaaacagct actgtaaatg tgacaaagcc agcttctggt tcttcttcta gcgtttttta
    32281 ttataaaaca ggagacatgc tacctgaaga tactaagcac attcgatggt ttttgaatat
    32341 taacaataac ggcacttatg ttgaacaacc agttaaaatc agtgatgaaa tccaaagtgg
    32401 acaaagatta gatccaagta cgtttgaaat taatcaaata cacttaggtg aacagaaggt
    32461 ttatagagga gaagagggaa tccaacaatt tttacaagat ttccccagcg ctacatttaa
    32521 tttttcagta actgataatt acattgaaat aactatacca aaaaactttg tcaatcttag
    32581 gaaaataatg gtgagttata agacgatcat agaaaaccca gaacaaataa attttgagaa
    32641 tcattcggaa gcttggttta aagaatttaa taaacctgct gttgatggag aaagtttcaa
    32701 tcatacagtt aaaaatattt cagcttctgg tggagtcaac ggtacagtta gaggcgaatt
    32761 gaagattttc aaatatatca atgacacaga gattggtatc ccaaatgtga ctttcgaatt
    32821 aagacgagca gatgaacagc ctattcaagg acagtctagt atcctgttga cttcgaatga
    32881 acagggagaa gctagtatca aaggcctgca agtaggagac tatgttgtaa aagaaaaaga
    32941 agcacccaat tggattgatt ttgatccact aagttcaaat gaactcaaat tctccataaa
    33001 cgaaaatgat acagagggag tcagtttacc tatttataac aagaaaaagg ttacgaacat
    33061 cacagcaact aaaatttgga acggtggaac cactccaaga ccgagtattt attttaaatt
    33121 attcagagca agtacaaaca attgggaacc agttcctgat gcagaaacaa aacgattaga
    33181 caatggaata acttcagtga cttgggaaga tatccaacag tatgatgata gtggaaacga
    33241 atatacgttt aaagtgcaag aagtagatca aaacggaaat gattatgtcc cttcaggtta
    33301 tcaaaaaatt gaaaacgggc tagtcgttac aaatgagaat aaagaagtca tttcagtctc
    33361 aggacaaaaa acatgggaag acaatgagaa ccaagacggc aaacgaccga cgacgatcac
    33421 agtaaatcta ttagccgacg gtcaaccgat ccaacacaaa gaagtaagtg aaaaagatga
    33481 ttggcgctat cgtttcacaa atctgccaaa atacagagac gggcaagaaa tcatctatac
    33541 tgtaacggaa gacaacgtgc ccgaatacag tacgacgatt gacgggtata acatcaaaaa
    33601 cagttataca ccggaaaaaa caaatatatc tataccaggt agccatataa caccgtggaa
    33661 aaattttcca gagaagacag agagagagaa aattagaaat ctattctctc aaaaattgca
    33721 aatatttgct catacaggag aatccagcga acaaagaagc aattatatta gtaagagagc
    33781 tgtacctaaa cagataacaa ataaatcaaa aagcattctt cctaaaacaa gtagtaaaaa
    33841 atctagtttt gctgtaatca ttggtttatt gatagtaact atctgtgctg ggatattctt
    33901 acaaaaatat aaaaaagttt agttagaata taatattttt tgttaaatat gactgaaatc
    33961 aaaagaataa aattccgatt tataatcgaa aaaagaagca tttttatata tgcttctttt
    34021 ttcgtagaat caataaatat ggatttggct aactatggaa gaatactcgt attagttttc
    34081 agcgttcata ctagttgtta cattgtttga ttggccaaaa gaatttctga tatattttgt
    34141 gctaaataaa gaaaaagacg cttgaattgg gaaataagaa aactactcta tcattacaaa
    34201 ttttcataaa ctggcagatg ttctaagtaa acaagtatct tttcaaagtc ggaaaaatcc
    34261 ataatcaacg tagtggtatt gatatttgga tgaaagccta cggtatcttg acgatcaata
    34321 gcagcatcga tcacgacttg gatttttttc tctttgtcgt gcatcaatgc taatggagtc
    34381 actgtacctg ctggaacgcc taggaggtca ggaagctgtt cttcagaaac aaaagataag
    34441 cgcttttctt ttaattgttc agctagttgt tttaaatcgg cgtgcttttc atcaggcaag
    34501 atgacaagat agatttgttt tccttttctt gatttcaata atagattttt tacttgcgga
    34561 ccaggtaggg aaaaagggac atttttgact gacgtaatcg caggatgatc gactttttga
    34621 aaagagatac ccagtttttt tagtagttca taagcttctt gttcggttgc acgactcatc
    34681 gcgcatcacc ctcctttttt tattagtgta tcataaaaaa gagttgacaa atgaaaaata
    34741 atcatgtaaa ttacacgtaa agttaaaaca aatgacatcg aaaagaagag tagccgttag
    34801 gtgtttttag agagtctctg gttggtggaa agaggcagca gttaaccgtg aaacacatct
    34861 tggagtcgat tttctgaagc gtatagtagg aaaatccggg gagcccgtta cagctgcggt
    34921 cgttgctaga tgaccagata aggctggctt ttccgtgagg agtcggtaaa aaaaggtgga
    34981 accacgtgat taacgtcctt tgatcttcgg atcaaaggac tttttgtttt catctgaacg
    35041 gcaacgactg tgtgaggttt tttctgcaag gaaaaaataa acagaggtgg aaccacgtat
    35101 aatacgtcct cttggcattt gccaagagga tttttttatt ttaaaggagg aaaagaagat
    35161 ggagtatttg attgaagtta tgccgcaatt attagtagga gcactcacaa cattgaaatt
    35221 atttttattt accttgattg gctcattacc attagggatt gttttagcat taggattgtc
    35281 tttgcatttt aagccgctac gctacttgct tcaaacatat gtatgggtta tgcggggaac
    35341 accgctgttg ttgcaactga tttttatttt ttatgggttg ccgacgattg ggatcgtttt
    35401 tgatcgtttc gaagcagcac tcattgcctt tatcttaaac tatgcagctt attttgcaga
    35461 gatctttcgt ggagggatac aatcgattcc tcaaggtcaa tatgaagcag cgcaagtttt
    35521 gcaattaagt ccctttcaaa cggtgacgaa aatcgtcatc ccacaagtga caaagattgt
    35581 tttaccttct gtagggaatg aagttatcaa cttggtcaaa gattcttcct tgatctatat
    35641 attaggttta ggtgacgtaa tgcgtgctgg gaaaatcgcg atggaacgcg acgcgacttt
    35701 actgcctttg ctaggcgtgg caatcatcta tcttacattg actggtattc taacaatcgt
    35761 aatgaaacaa gttgaaggaa aattaaatta ttaccgctaa ctgataggag gaagaaatat
    35821 gattgaattg aagaaagtga acaaagcatt tggtgaaaaa aaaataatca aagatttgaa
    35881 tctaatcatt ccagatggga aaacattagc tatcgtaggt ccttccggtg gcggtaaaac
    35941 cacgctttta cgtatcttgg ctggcttaga aagttctgac agcggagaat tttatttaga
    36001 cggtgtaccg ttcaacccat tcgagcttaa aatgaaagaa caagttgtag gagtcgtatt
    36061 ccaagacttc cagctatttc cacatctgaa tatttttgaa aacattacct tagcaccaaa
    36121 aatggtattg aaacagacaa aagaagaata caccaaaaaa gcagaagaat tagcggcttc
    36181 attagggatt agtgatttat tgaatatcta tccttatcag ctttctggcg gacaaaaaca
    36241 gcgggtagcg attgccagag cattggctat gaatccacgg gtattggctt atgatgaacc
    36301 aacaagtgct ttagatcctg aattacgcca gcaagtcgag cgtttgatcc tatcattgaa
    36361 agaagatggg gtaacccaaa ttattgtcac ccatgattta gtatttgcag aaaatgtcgg
    36421 tgatcaatta ctaaaagttt ccccaattca ttaagaaagg agaagataga gatgaaaaaa
    36481 accagttttc tattcgcttt gatcgcaggt cttcttcttt ttgcaggctg ttcgaacaaa
    36541 aaaacttcag cagataattg ggcgactatc aacgaagaga aaaaaatcgt tataggttta
    36601 gacgatacat ttgttcctat gggatttaga gataaagacg ggaagctcac aggatttgat
    36661 attgatttag ccaaagcagt ctttgaacaa tatgggatta cggtagactt tcagcccatt
    36721 gactggtcaa tgaaggaatt tgaactgaac aatggaacga tcgatttgat atggaacggc
    36781 tattccaaaa cgccggcaag agaaaagaaa gtgcaattta caaaacctta tatggaaaac
    36841 gatcaagtgc tgatcacacc taaagaatca ggaatcacaa actttggaca aatgaataat
    36901 aagagattag gtgcgcaaaa tgggtcatct ggttatgatg tatttacgaa acaaccagaa
    36961 gtattaaaag agatagtcaa aaaccaagat gctgttttgt atgatagttt taatgaagca
    37021 ttgatcgatc tgaaaagcag acgggtcgat ggtctgctga tggataaagt atacgcagac
    37081 tattatttga aacaaagaaa cgaactagaa gacttcaaca taacaaaagg ttcttatgag
    37141 agtgaggatt ttgcagttgg tgcacgcaag tcagatagta cattagtgaa aaaaatcaat
    37201 gaagccctag atcaactaga gaaaacaggt gaattccaaa aaatatccga taaatggttt
    37261 ggcgaagatg ttacgccgag aaattaacaa ataggggact gtgacaaaag acgtgtcaca
    37321 gtcccttttt ccgaataaac agtgttctcc tgccaactcc ttgtgactcg gagctgaatg
    37381 gcaggctcac aacctcttgg taaacggtgt tcaaaagcca gtttttcggt attaagccaa
    37441 atttatgcaa aaatgtagaa agccattttc acaaaatttt tcttactact cgaaactaag
    37501 cgactttttc acaacctcct ttacataatt ttattttgtt gtggaagggg tttcgtgtta
    37561 ttctaaaaga ggaacgattg aaggttatag gaaaggaaga gatgaatgga acacaaagaa
    37621 cttacctcat ttccaaaaga ttttctgtgg ggctctgctt ctgcagcgta tcaagtagaa
    37681 ggagcttggc aagaagatgg gaaaggagaa tcagtctggg atcgatttgt acggatacct
    37741 ggaaagacat ttaaaggaac gaacggtgat ttggcagtag accactatca tcgttataaa
    37801 gaagatattg ctttaatgaa agaacaaggt ctgaaagctt accgcttctc tgtagcttgg
    37861 acacggattt ttcctaatgg acgaggagaa gtcaatcaag ctgggctcgc tttttatgag
    37921 agattgatcg acgaattgat tgaaaacgat attgaaccta tgttgacttt atatcattgg
    37981 gatcttccac aagcattgca agatgaatat aatggttggg aatcacgtca gatcattgaa
    38041 gatttcactc attatgcaga aacattattt gaggcattcc gcgggaaagt ccattactgg
    38101 attagtttga atgaacaaaa tatcttcact tcattaggtt atttgttagc agcacatccg
    38161 ccaggtgtga cagacccgaa acgaatgtat gaagttaacc atattgctaa tttagcaaat
    38221 gcatctgtca tcaataaatt tcacgagtta gaaatgcctg gaaaaatcgg accaagcttt
    38281 gcgtatacgc caaattatcc aattgacagt aatcctgaaa atgttctggc tgctgaaaat
    38341 gcagaagacc tgatggccaa ttattggatg gatgtctata tgtggggaaa atatccgatt
    38401 gctgccatga ggttcttaga agaaaaagga tgggcaccaa cgattgaagc tggcgatgca
    38461 gaattgctag aatctgctaa accagatttt cttgggatca attactatca aacggcgacg
    38521 aatgcattca atccattaaa cggagttggt gctggaaaaa tgaatacgac aggaaaaaaa
    38581 ggttcatcag aagaaactgg agttcctgga atgtataaaa aagttgagaa tccatttgtc
    38641 gaacgaacaa attgggactg ggagattgac ccagaaggat taaggatcgg actgcgtcgt
    38701 atcacaagcc gttaccgcat gccggtactg attacggaaa atggcttagg agagtatgac
    38761 aagttgacag aagataaaca aatccatgac gactatcgaa tcaattactt acaaagccac
    38821 gtcaaagcca tcaaagaagc aatttcggat ggagcagaag tcctaggcta ttgcacctgg
    38881 tcttatacag atttgcttag ctggctgaac ggttatcaaa agcgatatgg atttgtatat
    38941 gttgattaag acgaaacaca agaaggatct ttggaacgat ataagaaaga cagttattac
    39001 tggtaccaaa aactgattga agaaaatgga gagaaccttt agttcacata cttaaaacaa
    39061 gaaggtacgg ctggatatgg ccgtgccttt tcttgataaa atcatttaga aattaagaaa
    39121 aactgtaaaa taagctgaaa aatgaaagaa agcgtcagtt ctttcaaaca aaactttagt
    39181 tcccttactt ttttttgtat aatgaaactt gatgaaatga gggataataa atggcacaaa
    39241 agaaacggcc tactaaaaaa aggaaaaaga cgaaaaaaac gaaaaagcaa aaacagcagc
    39301 aggaacaaat gctgacgatt ggtgttgggt ttgccttgat tttatttgct gtcttcggct
    39361 ttttaaaatt aggtttttta ggaatattga ttgcaaacgg ctttcggatc attgcaggaa
    39421 atacttacca aatcctctgt cttttattag ccgtattagg attttggatt gtcattaaga
    39481 atacagagtt ttcaattggt aaaaaccgac gctggtttgg cggcatactc ttttatttcg
    39541 gtatcttatt attgttacat gcccatttat ttggcaaact ccatactggg gaaccaaata
    39601 tcatggggac gacatgggat ttgttagcca gtgatataaa acaaagtcaa gtagacaata
    39661 acgttggtgg tgggatgatt ggagcaatcc tttatcattt tacttacttc ttgattgcac
    39721 agcctggaag ttatttagca gcagtgctat tactggcagg aggagcattc ctgttcagta
    39781 atctggaagg ctatcagctg ttaaatggta tccaatcaat tggagaacga gtacaggaat
    39841 tattggaagg tgatcctgcc aagcaagctc gaaagcaagc ggcaaaggaa gagagaatga
    39901 aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc aaaagaagct gcagaaaaag
    39961 aagctgcaga atatgagaag aaaaaagcgg tgagccagca aagggaaaat actgctgatg
    40021 aatggcagga accagaaaat acagagccgg agcagctaag ttttgttcca atcgacagtt
    40081 ttcaagaaaa tatccatcct gcgaatctag agaaaccagt accagataca ccaaaacaga
    40141 ccaatacagc agaaggtttt tcagatgagt tgccagagga tgacggtacc tcattagaat
    40201 ttgagattga agcagaacag gaaaatcaag actatgaatt accgacagtt gatttgcttg
    40261 attctatacc aactgtggat caaagtgatg agtataaaaa aattgaaaaa aatatcggcg
    40321 tattagaaca aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag
    40381 gaccatccgt cacaaaattc gaagtccagc cggctgtagg ggtaaaagta agtaaaattg
    40441 tgaacttaac agatgatatc gcgcttgctt tagcggcgaa agatgtccgg atggaagcac
    40501 cgattccagg taaatcactg attggtattg aagtaccaaa tggaaagatc agtatggttt
    40561 cctttagaga aatcatcgaa gcacaaccaa accacccaga taaattacta gaagtacctt
    40621 taggacgtga tgtttctgga cgggtacaaa cggctgatct ttcgaagatg cctcacttac
    40681 tcgtggctgg ttcgactggt agtgggaagt cagtagcaat taatgggatt atcacaagta
    40741 tattaatgcg tgctaagccc catgaagtaa aactgatgat gatcgatccg aaaatggttg
    40801 aattgaatat gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa
    40861 aagcagcgca agccttacaa aaagtagtac aagaaatgga agaacgatat gaaaaattcg
    40921 cggcaaccgg agtaagaaat atttctggtt acaatgaatt tgttcaacag aaaaacttgg
    40981 aaaacggaac gaaacatcca accttaccat tcatcgtagt gatcgtagat gaattagctg
    41041 atttgatgat ggtagccagc aatgaagttg aagatgcgat tattcgttta gcgcaaatgg
    41101 ctcgggcagc ggggattcat atgatcctag ctactcaacg tccaagtgtg gatgttatca
    41161 caggaatcat caaagcaaat gtaccttcca gaatggcatt tgcggtatca agcggtacag
    41221 attctcggac gatcattgat tctaatgggg cagaaaagct cttagggcga ggagatatgc
    41281 tattcttgcc aatgggtgag aataaaccga tccgtgtgca aggagcattc atttctgacc
    41341 acgaagtaga acgggtcgtt caatttgtta cagatcagca agaagctcat tatgaagaga
    41401 aaatgatgcc gacagatgaa gttgaaacga caggtgctcc agaacagcca caagatgagc
    41461 tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc
    41521 aaagaagatt tcggatcggt tacaaccgag cagcacgttt agtagatgaa ctggaagctc
    41581 atggagttgt tggcccgtca gaaggaagca agcctcggaa agtattcatt gagcaggaag
    41641 aaacatcaga aacgttgccg gacgataatg acatgtaaaa cttgtgtgat gaagggttga
    41701 aaaacgaata accaataaaa agacaaggca tgatgatacc aaaagaaaaa atggtttttt
    41761 tccatctttt ctaatacggt atgatgtctt gtctttttag tttttgtgag attaaagttc
    41821 tattcgattt atttgtgaag tattgcatta aggaaatgaa tcatgtatag tatgtagcga
    41881 aactttgaga aaaagaggga aaatactttg gaaaaacagt ccatttatgg cttgacgaat
    41941 gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt
    42001 tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa
    42061 caattgatcg aaaaattatc ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc
    42121 caagaagctt cggatggtac agtaaaatat ttgtttgaac tccctgataa aaacatgatt
    42181 gagactgtac tgatgagaca agaatatggc ttgtcagttt gtgtgacgac acaagtagga
    42241 tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg tgatctgact
    42301 gctggagaaa ttgttgcaca gatcatgatg gtccaacatt attttgatga gcgcaatctt
    42361 ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg agccatttga taattacgac
    42421 aatgtaatgg actttttgca tatcatcaat gatgccaaag gattggcaat tggtgctcgg
    42481 cacattacag tttccactag tggattagca cacaaaatca aggaattcgc taataacggc
    42541 ttgcaagtca atctggctat ttccttgcac gcgccgaata atgaggtgcg aacatcgatc
    42601 atgcggatca accgaagttt cccaattgag aaattgatgg aagctgtgga tgagtattta
    42661 gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt aaatgataga
    42721 ccagagcatg cgcaacaatt agcagatcta ttaaaagata agaaaaaatt agcatatgtc
    42781 aacttgattc catataatcc agtcagtgaa catgatcaat attctcgcag tccaaaagct
    42841 gatgtattga gattttatga tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa
    42901 gaacatggta cagatattga tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa
    42961 acagttgcca aataatcgta tcctactcgt tttttcaatt accataaaag gagcagtttt
    43021 cttaattaag gaactgttca acttaaataa gagaaaagat tctatagcga aagctataaa
    43081 gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc
    43141 ctgcttgatg ggggttttag caattattta actgattttc ttatatcctt gctggctttc
    43201 ttgtgtagca tgataagttt ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat
    43261 ttcataaggc acatgtttaa tatcatttgt tgccatggct ttatctaaga ttgcttctaa
    43321 atcggtcgtg acattgagat tcatgtcggt taacgatact ggaagttggt tctttttcat
    43381 aaacacatag attttatcaa acaaatcgaa ctgctgatcc atcatcaata aggtcagtac
    43441 accataactg acagatgctc cgtgaaggta tccctccatt ttttctagaa cagtcgtacc
    43501 gtaatagaat gagtgtgcca tagcagaatt atagttattg ttaactaaaa cagaaaccaa
    43561 tccggtagta acaatgatat ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc
    43621 ggcactatct ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc acatttttcc
    43681 gatttggatt cctaatctat ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga
    43741 ttcgacttct ttggataaag catcgccaat acctgcccat aagtatttat caggtgcttc
    43801 ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc
    43861 gtccattacg ccttcttcgt tatagatgac acataccgca gtgacgggcg aacagttcga
    43921 accaatagtg ggaaaggtga agactggttt agctagtttt tcaccaatga cttttacagt
    43981 atcgcaagca cggccaccac cgactgcaaa caggacgtct gctttttgga cactttcatg
    44041 ctggatcaac tgttcaatat ttccataagt tgaattaccc ccgtaccaga gactggcgac
    44101 aacctctatt tcctgtgtca aagctacttt tattttgttt tctgcctttg aaagtgcagt
    44161 cttccctcca atcagcacta cttttgtccc atattctttg acgattccat ttgctttttc
    44221 atacgcatct gttccaatgg tataatttgg taagaaaaca ctttgactca tattcatttc
    44281 cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga ctgcggctgt
    44341 agatggagta gaggtgaacc taagacagga taagtgatga ataaggtggc atgaacacct
    44401 tgaaatcatc aataagtatc ctaaaaacga acaagtacaa aaacattgaa aacgacaata
    44461 atgaattttt gttcctctta gtatttctac cgattccctt tgcttttttg taattatcta
    44521 aaaattctaa aaattaagat tattatatga aaacaggttt tatttgtcaa ttcataattg
    44581 gtttttttta aagcaaaaga taatctatat catgatgaac aaacagagtt ttttcctcca
    44641 attgatggct ttcctgatct ttcctatttt gaataaagtg tttctgtata attttttatt
    44701 ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa agatttttga
    44761 gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac
    44821 gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt
    44881 tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa
    44941 tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta
    45001 ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa
    45061 gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag
    45121 cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt
    45181 taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc
    45241 gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa
    45301 atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa
    45361 attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa
    45421 tttacgaaaa ttacttcttg aatttttgtg aaattccaac ttatttccga agaagctact
    45481 tttggaacac cgtgtaccag aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa
    45541 attttgtgaa aatggctttc tacatttttg cataaatttg gcttaatacc gagaaactgg
    45601 cttttgaaca ccgtttattc agataaggga ctgtgacaag acttttgtca cagtttcttt
    45661 ttgtttattc ttttttatct ttgtatggca ataatagaca atataacgaa aattatttaa
    45721 tggcttttgg aagaccatgg aaaaccttgt acaaagctat tttttctgaa aaattccttg
    45781 aaacctcacg aaaaaatcat tattttatga aaaagacaaa aaaaagtgtt gattttttaa
    45841 taattattca ttaaactctt aaacaacttc agaaaatatt aattattctg aaaattccaa
    45901 taaaggggta cgtaaaatga aaaagaaatt tacatttggt ttggttgcgg tatgcggcct
    45961 tgtacttgct ggatgttatg gcggcagttc agccacaagc agtagttcag caaaaagcgg
    46021 ttcagcagat ggaggaggcg tatttaactt agtcgtgcct caagaaatgc ctacagctga
    46081 cttatcagtt gcaacagata caatcagttt tacagcattg aataacgttt atgaaggaat
    46141 ttaccgtctt gatgaagaca gcaaaccaca gccggcagga gctagcgagt tggcagaagt
    46201 cagtgaagac ggattaactt acaaaatcaa attacgagaa gacgcaaaat ggtcaaatgg
    46261 tgatcctgtt acagcagcgg attacgttta tggctggcaa cgaacagtag acccagctac
    46321 agcttctgaa tatgcttacc tgtatgcgcc agttgaaaat gcagaagaca ttacagctgg
    46381 aaagaaagat aaatcagaac tagggatcaa agcagttggt gactatgaat tagaaatcaa
    46441 attgacgaaa caaacaccat atttccaata tctgcttgct ttcccatcat ttttcccaca
    46501 aaaacaatcc gtagtggaag aaaatgggga tgcctatgca tctgcaagtg ataaagctgt
    46561 ttataatgga ccattcacat tagaagattt tgatggacca ggaacagata cagaatggac
    46621 ttataagaaa aatgatcatt actgggacaa agatacagta aaactttctg aaatcaaagt
    46681 cagtgtagta aaagaatctt ctactgcatt gaacttattc aaagatggcc aagcagatga
    46741 cgtgatcttg tctggtgagt tagcacagca aaacgcaaac gatccagctt atacttctgt
    46801 taaagaagcg cggacaagct atatcgaatt caatcaacgt gaaaagaatt caccattcaa
    46861 caatgtgaac ctaagaaaag ctatttctta ttctatcgat cgtgaagctt tagtaaaaca
    46921 agtactaggt gacggatcag ttgtctctac aggattgatc ccatcagata tggtaaaaag
    46981 tccaacaacg aacgaagact ttgcaaaaga agctggaaaa ttagtttctt atgacaaaga
    47041 taaagcaaaa gaatattggg aaaaagcgaa aaaagaattg ggcgttgatt ctttagaatt
    47101 tgatttgatg gcttctgatg atgattcatc gaaaaaagta atcgaatatg ttcaaaactc
    47161 aatccaagaa aacttggatg gcgtaacagt caaaccaaca cctgttccat tctctgtacg
    47221 tcttgaccgc tcaacttcgg gtgattttga cgcagtacta ggcggatggg ctgctgacta
    47281 tgcagaccca agcagcttta ctgatttgtt tgtcacaggt aattcataca accgtggtcg
    47341 ctggagcaat gcagaatatg acgaagcagt taaagcagct tcatcaacag acgctggcga
    47401 tgaacaagcc cgttgggatg atttccaaaa agcaatcaag atcatctctg atgatatggg
    47461 tgtcgttccg gtgtaccaaa aagcagaagg tcacctagtg aatgaaaaaa tcaaaggtat
    47521 cgttcaccat gcggcaggcg cttcatggga ttacaaatgg acatacgttg aagaataatc
    47581 gttaataccg tgagcatgag aaaaaacgag gctgcggcaa atgtcgcaac ctcgttctca
    47641 tattcactta tcctaacaaa gaaaaaagca tgaaaatagc agaaagagca attagtattc
    47701 cggcaatgat cagccaaaag ctgtacatac cgtagctggc agacgagagc gtggaaaatt
    47761 ctggtttttt ctttcggttc cttgttcgtg caagatggac cgatcgctga aaatgatcga
    47821 agaaacccga agaaaagacc cataaaaaac cgccgataat cagaaacggc aatgaccata
    47881 agaatagatc attagataat tgaatgagtg taaaggaatg gttgatgaga ttttttatta
    47941 aaataaccag aatcagtaga aaagctactg cgtaggggat agattttttt ttcatttgat
    48001 tgctccttta tttttggttc attatctaat aatgtagcga aacatctgtc agaagtcaaa
    48061 agctaggggg aaacattagt gaatagttat atcaaatatg tattaaaacg tgtctttttc
    48121 atgatcatca cgctttggtt aattgcaaca atcacctttt tcttgatgca attgctgccg
    48181 ggcacgccat atacgaatca ggaacgtttg agtcctgaaa caatcgagat gctaaataaa
    48241 caagtcggtt tggataaacc agttatcgta caatatggga tttatctttc taatttgctt
    48301 caaggagatt ttggaatttc cttccaattt aaaaaccagc cagtcgcaca tttgttagct
    48361 ggaagaatcg gaccatcctt gcagttaggg ttacaggcaa ttatctttgg aacagtccta
    48421 gggacgattt taggaacgat ctctgccatg aagcaaaata catgggcaga tacatcttct
    48481 acactcgtag cgatattagg tcgttccatt ccaaactttg tatttgctgt tttattacaa
    48541 tatatctttg caatcaaatt acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac
    48601 acaatcttac caacaattgc gttggccatg tcgccgcttg ctgactctgc tcggtttatc
    48661 cgtacggaaa tggtggaagt actgcatagt gattatgtgg aattagcaaa agcaaaagga
    48721 ttgagccgtt gggaaatcgc ctttaaacat ggtcttcgaa atagtttgat tccattgatg
    48781 actttattag gaccgttagc tgtagcattg atgaccggat cactggtggt agaaaatatc
    48841 tttgctattc ctggtatcgg ggaacaattc gttaagtcaa tcacaacaaa tgattatcct
    48901 acgatcatgg ctgtaacgat cctttactca tttatgctga tttttgttat tttgatcgtg
    48961 gatctattgt acggtctagt tgatccaaga attcgtgttt cagaagggag ccgaggataa
    49021 atggaaatga taccaaagcg ttatgaaaca gttgcagata tccctgcgga tgaatttctt
    49081 ccattacaaa aaaataccga agaagaacgt gaacagatta ctgcaccttc tttgaatttt
    49141 atccaagatt catggcgccg tttaaagaaa aacaaagctg ccgttatttc aatggtttta
    49201 ctattggtca tcattttgat ctctgtgatc acaatctttg tttctcctca tgatccaact
    49261 gcccaaaacg tggcttatat caatttgcct cctcgtattc cgggaatcaa tatcgatgga
    49321 ttgaatggaa aagcaatggt tggtggtgaa cttgttgata aatatgctca agcaaacgtc
    49381 ccttcaaacg taaatttctt tttaggaaca gacggtttgg gacgtgatgt attaagccgc
    49441 ttatttatgg gaatgagaat ctcgttgctg atcgcattta ttgctgcatt actagatgta
    49501 acgattggtg tagcttacgg gttggtttct ggtttgttag gcggacgtgt cgataacgtg
    49561 atgcaacgtt ttttggaaat cttatcagga attccaaacc tcgttgtcat gattttgatg
    49621 ttggtcgttt ttgaaccagg aattttttca atcgtggctg ctatggccat cacaaactgg
    49681 ataccaatgg cacgtatcgt tcgtgcacaa acaatgaaat taaaagatca agaatatgtt
    49741 ttagctggat tgacattagg tgaatcaaga atgaaaattg cattcaaaca tattttgccg
    49801 aatatctcta gtgtcattat tattcaaatg atgtttagta ttccatctgc tattttcttc
    49861 gaagcctttt taagctttat cggtttaggt cttacgcctc cgtcagcttc attaggaacg
    49921 atgttgagcg aagggtacaa gacattcctg tatctgcctt atctattatg gattccggca
    49981 gtaactttat cggttatcat gattggcttt aacttacttg ctgatggatt gcgtgatgcc
    50041 tttgatccta aaatgaaaga gtgaagacga tgacgaaaat tttagaagtg aaagacttag
    50101 aaatctcttt tgatacgtat gctggaaagg tacgagcgat tcgcggtgtc aattttcatt
    50161 tgaataaagg agaaacattg gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga
    50221 ccagaagcat catgcgcttg ctgtcaagca acgccaatat agatgctggt caaatcctct
    50281 ttaaaggtaa cgatatcgtt ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag
    50341 aaatagcgat gattttccaa gatccaatga cctctttaga tccgacgatg cccattggga
    50401 agcaagtcgc tgagtccctt agaaagcata ataaagtttc aaaaaaagag ggacaaaaag
    50461 ctgcattaga attgcttaaa ttagttggaa tacccgaagc tgagaaacgt atcaacagtt
    50521 atccgcatca gttctcagga ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat
    50581 gttatccgga aatcctgatt gctgatgaac ctacaacagc gcttgatgtg actattcaag
    50641 cacagatttt ggagctgctg aaagaaattc agacaaaaat cgatacatca attatcttta
    50701 tcactcatga ccttggtgta gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag
    50761 gaagaatcgt tgaagttgga acatcggaag aaattttcta caacccgcaa catccctata
    50821 cttggggact gcttggttca atgccgacat tagatagtgc gaacgatcga ttgtatgcta
    50881 ttcctggttc tccaccggat ttattgaacc cgccaaaagg agacgcattc tatccaagaa
    50941 atgaattcgc gatgaaaatc gatgcagaac aagaaccacc attttttgaa ctatcaaaaa
    51001 cacacaaggc agcaacttgg ctacttgctc cgcaggcacc caaagtgaca ccgccagaag
    51061 aaatccaacg tcgctgggct atctttaaag agaaacaaaa acatacttac ggtcaaggag
    51121 gaattgctga tgccaaataa actacttgaa gttaaaggat tgaaacagta tttcaatgta
    51181 ggaaaaaaga atgaagtaca tgctgtaaat gacatcagct ttcacattta tgaaggagaa
    51241 acattcggtt tagttggaga atctggaagc ggaaaatcca ctactggccg tacgatcatt
    51301 cgcttgaatg aacctactga tggtgagata ttattcgacg gtcaagatat aacgaagatc
    51361 aaagataaaa aaggtttgac gaaattccgg catgatgttc agatgatctt tcaagatcca
    51421 tacgcttcgt tgaatcctcg tatgaaagtc agagatatca ttgccgaagg aattgatgtt
    51481 aatggactag ctaaatcatc tgaagagcgt gcaaaaaaag tcgatgatct attgagaact
    51541 gttggattga atccaagcca cggtactcgt tatcctcatg aattttcagg tgggcaacgc
    51601 cagcgtattg gtattgcacg agcattggca gtaaaaccgc gttttatcat ttgtgatgaa
    51661 ccaatttctg cactagatgt gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc
    51721 caaaaagaac atcaattgac ctatctattt attgcacatg atttgtcgat ggttaaacat
    51781 attagtgacc gaatcggtgt aatgcataac ggcttgttat tagagatggg aacaagtgat
    51841 gaaatctata atcacggtgt tcatccttat acagaaagtt tgttatctgc tattcctcta
    51901 ccagatccag accatgagag aaaacgcaga agaatcaaat atcaacctga accagatgac
    51961 ggacaagtac gtcaacttcg tgaaatcgca ccagaacatt ttgtctatgc aactgagcag
    52021 gaagtcccat attacgcaaa aaaactaaaa cgacaaaagg aatctcttct ggttgctaac
    52081 taggagggac atagatgcta aaagctttta aattccgtat gtatccgaca gaagaacaaa
    52141 aacagcaatt gattcgtact tttggatgtg ctcgatttac ctataaccat ttgctgaaaa
    52201 agcggcagaa aagttggcaa caaacaggag tagccaattt ttcgctcaca cccgctacat
    52261 taaaaaaaga atacccattc ttaaaagaag tagacagtct tgctttagca aatgcacagc
    52321 ttaatttgga tcgggctttt cgcaattatt tcaagggacg tgccagcttc ccaaagctta
    52381 aaacgaaaaa aagtatgtgg caatcttata cgaccaacaa ccaaacccgt acgatctatc
    52441 tggaaaatgg ctacttaaag ttaccaaaac aaaaagaact aatcaagata aatcagcatc
    52501 ggccagttga aggatcgatt cgctccgcta cgatttctgc tcgatataat gaagaatttt
    52561 atgtcgcact actttgtgat gtttcgccag taaaaaaaga atctttagct aaatggatcg
    52621 ggatcgccta tcatccgaag acattgatcc aaacatctcg acctctagaa gtaactttac
    52681 caaaatttca ccagacagaa gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag
    52741 tccgctccgc tcaccataga aagatcaggt tagatcaggc aagcaattat cagaaacaaa
    52801 agagaaaagt aatggatctt tatctgaaac aaaagaacca gcgagaagat tatcttgaac
    52861 aattatctgg gaaattggtc aaacaatatg actacttatt tgtagaatct tttccaaaag
    52921 aagaggcaca tgctgatttt tctattcacg actggcataa attaataaca aaattgcgtt
    52981 ataagtccca atggtataat aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa
    53041 gcaattccgt aagaaagagc caagtagtag aaaaaatggg cagacattcg gttatcaagg
    53101 gataaaaaat gaatgaaact gataggagcg ttagggttag ccttgttaat aaaaagtctt
    53161 aatgactttt gtttctagga atttttcttt tgaagaaaag ctcactaatt atgacaaacc
    53221 aataaaacaa tagcagaaaa agttcgtacg agctttttct gctattgtta attttttatt
    53281 cagaaagttt acgaatacat caaaattctg aaacaaaaaa cgtaactcac aaagagttgt
    53341 ttttgcgttt tttcttgaat gattaggtct gaatcttttg ctcacaacct tattcatggt
    53401 gccccggctt gagctgatag atttttgaag gacggccgat tcctacagga cgttcaccga
    53461 tctcatcgaa atattggagc atagctttct taaaattgga atgatcgatc gttttataat
    53521 cgatccctaa gaatttagca aatacttttc gagcttccgt aatcgtgaaa tctttaccta
    53581 aaacttgtag aacttgcggc tcgtgttcca ttttattgac tacacggttg aatgctttca
    53641 agatgatttg actatggtca aaagccaaag tatctttgcc agaagactct ccagtgacta
    53701 aatcaagcga gatagccact tctccgctag ataaatggat cttgttacta tgacgttcta
    53761 gtgtgaacca gcgtacttcc ttggcatcat ctccggcgat tagcggttct tctccaataa
    53821 aggctaagta gctgactgtg acgacccagc ctcgcggatc tcgattaggc gtactgaatg
    53881 tatgcagttg ctcaatattt tcttttgaaa taaccacacc agtttcttcc tttgtttctc
    53941 ttaagacgct ttctccagtt gactcatcct tttggacaaa gccaccaggc aatgcccatg
    54001 aatttcgata aggatgccct tttctttgga tcaacaaaac tttcagctga tcttcttctt
    54061 tgttatagca catcagtacg atatcgacag tcaaagaggg cttgtcatat tctggacgtt
    54121 cctgtttttg ataccagtta agaaattctt cttcacttgc tttatgttca taatataatt
    54181 tttcttcttc tttagaagca aaacggttca tctgaccacc tccattgaca gtaaaagtac
    54241 tttttacctt attgtagcag actctgaaaa aaaaccaagg atttacttga aaaatctagg
    54301 ttatcattta aatatgaaaa ataaatggaa gtatgagatt gaataaaaag aaaagcagat
    54361 aaaacggcaa tactttatac cgctcttcac gaatggcaaa gaagccacaa ataacgatat
    54421 atacgtcaat gataaaacgc aaaatccaag ctgctgtcat aaaactgttc aaatgcccat
    54481 ggaggttaaa ataaccatac atacgaatat aaaaatagct gaatattaaa tgtgctaatg
    54541 aaagaaaagc aatactaagt gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc
    54601 cttactaaga tagatagtct ttattatacc acgtgtgagg ggagaaataa aaagccgttt
    54661 tttagtagat atgaaacaaa acaaaaaccc gcatttattc aacctattca tccttttaaa
    54721 ggatagattg aacgtagata gaagtcgttt atccagtctt tttcattttg aaaaaaagct
    54781 aacagcatgc tttttttatg gtatactagc aaggaaacga attcgcatca tgcgataaag
    54841 gaggaagagc cccgtggcag aaaaggaaac tttttatatc actacgccaa tctattatcc
    54901 aagcggcaaa cttcatatcg gcaactcgta tactacgatt gcatgtgacg caattgctcg
    54961 ttataaacgg ttgatgggct ttgatgtgtt ttatctcact ggagtggatg aacatggtca
    55021 aaaaatcgaa acaaaagcag aagaactagg tgtaaaaccg caagaatatg tagataaaat
    55081 ggcggctgat gtcaagaaat tatggaaaac gcttgatatc agttatgata aattcattcg
    55141 cacgacagat gattaccata aagcagctgt tcaaaaaata tttgatcgtt tattagaaca
    55201 gggagatatt tacttaggtg aatatgaagg ctggtactct gtttctgacg aagaattctt
    55261 tacagaaaca caacttgcag aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa
    55321 agcgccaagt ggacacgaag tagaattggt aaaagaagaa tcatacttct tccgcatgag
    55381 caaatacgca gaccgtctat tggaatacta tgaagaacat cccgaattca tccagccaga
    55441 atctcgtaaa aacgaaatga tcaacaactt tatcaaacca ggattagagg atcttgcagt
    55501 ttcacgaaca acttttactt ggggagtacc agtcaagagt gatccgaaac atgtggtgta
    55561 tgtatggatc gatgcattat ccaattatat tactgcacta ggatatggct ccgaagatga
    55621 aagtctattc gaaaaatact ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg
    55681 ctttcatacg atctattggc caatcatgct gatggccctt gatttgcctc tacctaaaaa
    55741 agtatttggg catggctggc tattgatgaa agacggaaaa atgtctaaat caaaaggaaa
    55801 tgtcgtttat cctgaaatgc ttgtggaacg ttatggttta gatgcactcc gttattattt
    55861 gcttcgtgct gttccgtttg ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg
    55921 tgtcaattat gatctggcaa atgatctagg gaacttattg aatcgaacga ttgctatgat
    55981 caacaaatat tgtgatggac tcgttcctga ctatgcctca cttgtcactc catttgatag
    56041 tgaactgtct acgacggctg ctaacgttgt cggacgttac catgatgcaa tggaaaaaat
    56101 ggaattcaat acagcattgg ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat
    56161 tgatgaaaca gaaccatggg tattagcaaa agacgaagaa aagaaagctg aattgaatag
    56221 tgtcatgatc catttagctg aatctttgcg tatcgcagcg atattacttc agccaatcat
    56281 gacagaaacg ccagagaaga tcttcaatca actaggattg gactctgaaa caatgaatct
    56341 tgaaggatta cactttggcg aatttccttc aggaacaaaa gtagttgcaa aaggtacacc
    56401 aatcttccca cgtttagata tggaagaaga agttgctttt attcaagaaa aaatgtctga
    56461 aggtactcaa acaaacgaag atacagtcaa atgggatcca gaagaaacag aacttgtttc
    56521 aacgaaagaa aaacaaatca aatttgatgt atttgaaaaa gtagaactaa aagtagcaga
    56581 agtcatcaac tgtcaaaaag tagaaggggc agataagttg ctgcaattcc gactagatgc
    56641 tggagacagc caagaccgtc aaatcttgtc aggaatcgct gaattttatc ctgatccaag
    56701 cgaattgatc gggaaaaaag tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg
    56761 acaaatcagt caaggaatga tcctttctgc agaagcacca gatggctctt tacaagtaat
    56821 cgaagcacca aaatccatgc caaatggctc agaaatcgca tagaaattca aagggggtat
    56881 gacactagtt gtgtcatacc ccctttttcc gaaatttgag aagcaatttt cgtaaattcc
    56941 ttcttattac ttgaagccaa tcatataata cagaaacaga gaactatcca aaataaatcc
    57001 tagaaaaaga agtacgagct tcgctgattt ttgttaattt agaataatac taataggaat
    57061 cgtaaaaaca gaaaaaaagc ataatgataa agggtcgggc agattttaat tgattcatct
    57121 ggtactcttt tttattgtcc ttacattcat aaagtttgaa tgcaatgact ttattacatc
    57181 tatatttata tctaacagta gcgttgatgt gttaattata agttctatca ctttatgttc
    57241 aattagtttg tgctcttata tgtgtgattg aaaatataga taaaaaaaca atcatcggct
    57301 ttgacttcga tgattgtttt ctttattttg taaaaatcct atcacttgat tttatggtaa
    57361 ccttttattt ttgtcttcaa acggcttggt aagagagcag taagcagtgc aaatgggatc
    57421 gaaaagacat accagaaaat cgtacgtccg ataccataat gttgatagag ctttgtcaac
    57481 atcacgtgta acaagatcaa ccctaaaagc aaggagccag ctataaacca atgattatcc
    57541 caatgcatga cttcactaag tgccatcact ccaaaaggat agaaataaaa atagatcccg
    57601 actaaggtca tccgccagtt ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct
    57661 gaaagcaaaa taccgatagg cggaaaaagc ccaaccaaaa aggaatacaa catcccccac
    57721 aagatcatca caggaccttt gatcaatgca acgattgcga tgaacaaagt cagcaatatt
    57781 agtttttgtg ataacgttgc aacagtcatt aatccaaata aaattaatgt gaaccaatgc
    57841 caatgggact gctgttgttc tttacgggaa aaatcgaccc ggttggataa ataatctgct
    57901 aatttcggat aagaacgctt aaaatccata aactgttcct ccttcgtgga aaaggtaggt
    57961 ttagtatacg aaaaataaaa aagaaataca tccgtcttaa gagggagttt ttcactgaaa
    58021 gtggagaaaa aagaatggta aattaaaata ttctcagtta tactgaaaat tataccaaat
    58081 ttcaaagaag aaagaggatg ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg
    58141 gcgcattagc taccgttatg ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg
    58201 ctgttactgc tagtactcag tctacaagtt tgacattgct agcttggctt ttgggtggtt
    58261 tcttaacgat ctgtgctgga ttgacagtgg ctgaattagc tacagcaatc ccggaaactg
    58321 gtggagctgt aaaatatatt gaagctgcgt atggaaaatt gcccagcttt ttattaggat
    58381 gggcgcaaag cttgatttac tttcctgcta atattgctgc attatcgatt atctttgcga
    58441 cacaattgac gaacttatta caattatcta ccgattatct tttgttgatt gcagtgatca
    58501 ccgctgtttc tgtgacaggg ttgaatttgt tagggacaaa agtcggtgct tctgtacaat
    58561 cagtgacgtt gattgttaaa ttaataccaa ttgctgtgat tgtcatatgg ggattattga
    58621 ccccaggaca aggaactgtc cagttatttc caatcgaagc tggaaaagat gttacttttg
    58681 tcgaaggatt gagcagtgcg ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg
    58741 tcggtgcaat ggcaggggaa atgaaacggc cggaaaaaga tttgcctaaa gcaattattc
    58801 ttggtttgag ttttgtaaca gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt
    58861 tgccgattga tcatcttgcc ggtaatttga atgcagcttc tgaagcatca gacgtcattt
    58921 ttggaggaat cggtggaaag ctggtcacta ttgggatctt gatctcggta tacggtgcat
    58981 tgaacggtta tacactaact gggatccgcg tgccttatgc gatggcttta gaagacgagc
    59041 tacctttcag taaacagctg acaaagcttt caaagaagtt tacggttcct tatgttcctg
    59101 cggttttcca gttagcagta gcttgtatta tgatgagcct tggttctttc gactttttaa
    59161 cagacatgtt gatttttgtg atgtggctat tcagtttact gatttttatc ggtgtcttta
    59221 ttttaagaaa aaaagcgccg gaattgccac gtccatataa agtaccactt tatccaatcg
    59281 ttccgattat tgcgattctc ggtgctattt tcattttagg tatgacgatg atgacgcaaa
    59341 cgaaattagc attgatcggt ataggtgtta ccttgatagg tatcccagtc tattatcaaa
    59401 aaaagaaaaa acgctcagaa gagtaaaata tttcaacaac agacagaaaa agtacgaact
    59461 aggtcctcta gatcttcgtg ctttttctat ttcaataaaa caagttcttc tattttgatt
    59521 tttgctactt ctgcaagtag tgcttatgtg ctaaagtaag aatgaaaagg agagataaac
    59581 atgatatttg attctcatac ccatttaaat gctgaacagt tcaatgaaga tattccagaa
    59641 acgattcagc gagcacaaga aatgggggta acgaaaatgg cggtcgtggg cttcgatacg
    59701 ccaacgattg aaaagtcttt gcaattaagc catgactatc caaatatata cagtattatc
    59761 ggctggcatc cgacagaggc tggcagttat acgaaagaaa tcgaaaataa attacaagaa
    59821 caattgactt taccaaaggt tgtagcatta ggggaaattg gcttggatta tcattggatg
    59881 gaagacccga aagaagtcca agataaagta tttcgcagac agattgctat cgcaaaagaa
    59941 atgaacctac caatcagtat tcatactaga gaagcacttg aagacacgta tcaaatccta
    60001 aaagaagaag atgttcgaga tatcggtgga atcatgcata gtttcagtgg tgattatgaa
    60061 tgggcaaaac gatttcttga cttagggatg catatttcat ttagcggtgt cgtcactttc
    60121 aaaaaagcat tagacgtcca agaggctgca gcaaatgtac caatcgaacg attacttgtg
    60181 gaaacagatg ccccttatct ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc
    60241 tatactcgtt atacagtaga aaagattgct gaacttcgga atcttccgac agaagaagtg
    60301 gctgcccaaa catggacaaa tgcgcaccga ttatttggtc taagcgaaca tggataagat
    60361 gaagatccaa gagattatag tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt
    60421 agttgatgca gatacgatag aaacaatagg gtctgcaatc aatgaagaga tcctgatgca
    60481 aattgaacat gcccaagaga ctcgtggagt gatcgttttt accgatcctg atttttcagg
    60541 agaaaaaata agaaaaatca ttatggaagc tgttcctcag gcaaaacatg cttttttgcc
    60601 gcgcacacaa gctaaaccaa agaaaaaggg aagccttggt gtcgagcatg caagtgatgc
    60661 tgctatttta gaagcattga aaaaggtcgt gacgccagac atttcccaaa cggctgtttc
    60721 tgaaatcact agacaagacc ttttagacta tggtttaata gctggggcac aagcaaaaga
    60781 aaaacgagaa aaactaggtg acgagttgcg catcggttac acgaacggca aacaattgga
    60841 aaaacgtttg aagatgtttc gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt
    60901 ggaggaacaa catgagtgaa tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt
    60961 tattgaaaca tggtttttca tttaaaaaaa gtttaggaca aaattttctg actgaaccaa
    61021 atattttaag gaaaatcgta gaaactgcgc aaatagatga acatacgaac gtgatcgaag
    61081 ttggaccagg aatcggtgca ttgacggaac aattagccaa gcatgcaaaa caagtcgtag
    61141 catttgagat cgatgatcgt ttgatccctg tattggctga tacgatgcaa ccctatgaca
    61201 atgtgactat tgtacatcaa gatattttaa agaccgattt gtcaacagct gttagagaaa
    61261 catttcatga ggagcttccg ttaaaagtcg tagcgaattt accttactat attacgacac
    61321 cgatcatgat gcattttctt gaatcagatt tggttgtgga tgaactagtc gtcatgatgc
    61381 aaaaagaagt agctgatcgt atctctgctg aaccaggaac gaaagcttat ggttcattat
    61441 cgattgctgt tcaatattat atggaagcca gtttagcatt catcgtacca aaaacagtat
    61501 ttgtccctca gccaaatgta gattcagcga ttttgaaact gacaagaaga gatataccgg
    61561 cagtcgaagt gacagacgaa aaagcatttt tccgattgac aaaagcggca tttcagcaaa
    61621 gaagaaaaac gctttggaat aacttgcagc attcgtatgg caaagatgac cagacaaaag
    61681 catggttagc aaaaagcttg gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt
    61741 tgtcattaca agaattcgcc gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa
    61801 agaggttgtg acagaagttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa
    61861 caaaaatagt tcctcatgtt tttcgtttgt ttgggcttat taccgcagat gcaagctttt
    61921 gaacaccgtt taagaaagag gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa
    61981 tttcaaaaaa cagcttctca tgtttttgag ttagttggtc ttattacttg atgcaagctt
    62041 ttgaccacta ttatgccgaa caaggagatg tgacacaaat tttgtcacat ctcctatttt
    62101 tgtttcttga tcaaaaaatt cttatacttg atactcacac tcattttgta tggatttaga
    62161 aaagaatatg tgtcttgaca gttattagta agtgagttat actaagtcga catttatgtg
    62221 tcaagacata ttaggagaga gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt
    62281 ctgctttatt gattgggatg ggggtcatta tcccaatggt catgcctaaa atcatgattc
    62341 caccagcttc ctttactttg gcgtctcatg tgccattatt tattgcgatg ttttttacac
    62401 caggagttgc agtggctgtt gcgctaggta cgacatttgg tttcttttta acaacgccgg
    62461 ttatcatcgc attgcgagca ttgtcacatc ttgtgtttgc gttgattggg gcttggtact
    62521 tgcaaaagca tccgagtatc gttttaaaaa atggacagtt tacttttgct aattggcgtt
    62581 tccaagggtt caattttgtg atcggtgtga ttcattcttt agcagaaatg ctagtagtca
    62641 gcatctttta ctttattggt aatatgcctg aaacatatta ttctcaagga tatttttata
    62701 cagtattcat cttgatgggg attggtgggc ttatccacag tttagttgat tataatattg
    62761 cttattttat agcaggaaca ctcagcaaat attttgatat ccccgtattt acggcagcaa
    62821 aaaaagaaaa tcggaaagag tcgattcaag ggtacgcgaa gaaaacgaca tattagacat
    62881 gatctctcaa aaaaaaaact ctcatctagt aatggataat aaatcctcta agatgagagt
    62941 tttttgtcct aaaaagagct gcaccaacat cttctggcac agctctaaca gggggcaatt
    63001 tatggaagtt tgatgacttg ttctgtttct ttatcaaaga agtggccttt gctgatgttg
    63061 aaggcaaggt cgactatttc gcctggttta tggaaatctc ttgcatctac ttttgagatg
    63121 aactcagtag aaccagtttt tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg
    63181 acaacttctg atttcactac ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg
    63241 atgtcttctg gacgaatacc gaagataact tcttttcctt cataaccttt ttcaactaat
    63301 actttgtttt ttccttcagg aatacgaagc ttaagcccat gtccatctgt gataacacca
    63361 tttttcaatg tcacattaaa gaagttcatg gcaggagatc caataaagcc ggcaacgaac
    63421 atattgacgg gtgtatcata aacttctttc ggtgtaccga tttgttggat aaatccgtct
    63481 ttcatgataa cgattcggtc agccatagtc attgcttctg tctgatcgtg agtaacatag
    63541 atggtcgttg tttcaagacg ctggtgaagt ttggcaatct cagcacgcat ggctacacgt
    63601 aatttagcat ctaaatttga taatggctca tccattaaga agacttttgc atcccgaacg
    63661 attgcccgtc ccaatgccac acgttggcgt tgtccaccag ataaagcagc tggttttcgt
    63721 ttcaagtatt ctgtcagacc taagatctct gctgcattgt ccacacgttt tttgatgtct
    63781 gctttatcat atttacgtaa tttcaagcca aaagccatat tatcaaaaac agtcatatga
    63841 ggatacaatg cgtagttttg gaaaaccatg gcaatatcac ggtctttagg tgccacgtca
    63901 ttcatgactt ttccgccgat atttagttct ccttcagaga tatcttccag tcccgcgatc
    63961 attcgcaaag tagttgactt tccacaaccg gaaggaccaa caaaaacgat aaattcacgg
    64021 tctttgattg atagattaaa atcagttaca gaataatttt ctgcattgtc atatttttta
    64081 tatacgtttt tcagagccat ttctaccata atacgttcca cactttcttt tttagtttta
    64141 ttaactattt aaagtataaa tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa
    64201 ttttttcttt tttttgtcaa tgtgctagtt ttaagcttta ataaatatcc ataagaaata
    64261 aaaactgata cactggagta aataagtatg ttaacaatat caaaaggagt gtctcttatg
    64321 aaaatcgctt tgatcgctca tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg
    64381 tataaaacaa tattggaaaa acatgaactt tttgctaccg ggacgactgg gcagaggatc
    64441 acggaagcaa ccggcttgcc gatccatcgg tttaaatccg gaccgttagg cggggatcag
    64501 caaattggag ccatgatttc ggaggatcag ttagatttgg tgatttttct tcgagacccg
    64561 ctggctgcac agccccatga accagatgta acagcactta tccgtttatc tgatgtctat
    64621 gagattccgt tagctacgaa tatcggaaca gctgaggtgc tactaagagg actggaagcc
    64681 ggcttcctag attttcgaag aatcgtccat gaaatagaca agcatccact ttcattttga
    64741 tggataagcg tatggaaaaa taacgtttaa tgttcgccta tatgtagcta taaaagctaa
    64801 acaaactgat aatatgcgat ataatacgaa cgtattggat aatataaaca ataatattag
    64861 tttttcgtat ttgcagtaaa tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa
    64921 aaataataca gagtagaaaa taaagcgtta agtgctaaga ggatgggatg ttgcctcttg
    64981 gacgaaggac gtaatgttcg cggttttatt ttcgcattcg ctgcatgata cgatgtagca
    65041 gctcttaaag gagatgctaa aaatgaagaa acaccggtta gacgcacgta tgattgctat
    65101 tatgggctta ttgattgcat tgatggtcac tttgtcccga ctggtagcaa tcgagacccc
    65161 atttattaaa atcagtgtca catttattcc acaagtgatc atgggcattc tttttggtcc
    65221 tttttggtca gggataggcg cagttttagc tgatttagta ggaatggccc tcttctcgaa
    65281 atctgcattc tttattggat ttacattgaa tgcatttatt gaaggagcaa tctacggatt
    65341 ctttttctat cgaaaagaga tcacttggaa aaatgccatt ctggctacgc ttagtgtcac
    65401 gctgatcatc aacttatttt tgacaccatt atggcttgcg ttgatgtacc atgtgccatt
    65461 gttcagctgg gtcgtttggg cgccccgcct gttaaaaaca gtaatatggt taccgattca
    65521 atcaattgcc atttattacg taggacgtag tattccttac aaaaaaattt taagaagttt
    65581 agcgatccac gctaaataaa aaacaagcag tcttcccatc ccagaagact gcttgttttt
    65641 attgtgctgt gaattgtgct tgatagagcc gtcggtaata accatctttt tgaagcagct
    65701 catcatgggt gcccatttcg acaatagctc cctgatccat cactaatatc tggtccgcat
    65761 ttttgattgt ggacaggcga tgggcaatca caaaactggt ttttccttcc atcattgcta
    65821 agaaggcttg ttggattttt ttctctgtca atgtatcgac tgagctggta gcttcatcta
    65881 agatcaacat agggggatta ctgatcatcg ttcgagcaat cgtcaacagt tggcgttgtc
    65941 catctgatat ctttaaccct tgaccgccaa tcttagtatc taatttttcc ggcaaacgtt
    66001 ctacaaattc atacatataa gaggctttta gggcatcatt gatttctgcg tcacttgctt
    66061 ccggattccc aaaacgaaga ttttctcgca atgtactgtc aaatagccaa gtatcttgta
    66121 acaccattcc aaaactttta cgtaatgtat cacgttggat agagcggatg tcatggtcat
    66181 cgactgtaat tgttcctttt gttgtgtcat aaaaacgcat cagcaaatta acaagtgtgg
    66241 attttccggc ccctgttttt cctactatag caatggtttg acctggataa gcagtaaaat
    66301 tgaaatcttc gatcaaacgc tgcttggggt cataagaaaa agaaacatga tcaaaagaga
    66361 cttttccttt gatatttttg ggttccaagg cataggcatc tggcaaatca ggcttttctt
    66421 ctggctgatc gatcaaatca aatgctcgtt ctagaccaga aaaagcggtt tgcagttgtg
    66481 tcgtgattcc agaaagttcg ataaatggtt tagaaaactg acttgagtag atcgtaaagc
    66541 tggaaatcac accaacagtg attgacgaac cactcttcaa tgccaatagg ccgccaacta
    66601 aaccaatcga taaataagca aggtgatcta caaaacgaga agacgggttt gtcaaggaag
    66661 aagaaaattg tgcccgttgt cctttttcat atagatcagc atttagcagt tcaaattgct
    66721 gttgactagc ttcttcttgc tgaaaagctt tcacgatttt ctggttaccg attcgttcgg
    66781 tcacaaagcc cgagatatcc ccaataatcc tttgctgtct atcgaaattt gtttgtgaag
    66841 cacgagcaac gatccaactc acaaggaaaa taattggtgt agaacaaaga acgaccaatg
    66901 tcagaagtgg acttagacgc atcataaaaa taaacgaaag aatgatgatt gccactccag
    66961 aaaataattg attgaaggcc gcagaaattg caatggaaat attgtccata tcatttgtaa
    67021 atcgactgac gatatttccg tgggagtttt gatcataata acgaagtggc aatcgattca
    67081 gatgagcaaa tgcatctttt cttaattttg caacggataa gtaagctaac cgattgctta
    67141 acacttggat gagccattga ctgactacgt tgattaaaac gataccaccg aatagaataa
    67201 gtaaatggaa cagtcgattg aagcggacct gtccttctcc aatcatttga tcgatacttt
    67261 gaccaatttg taacgtcatc acaactgttg caatcccatt gatgattcct agtatcacag
    67321 ctagccaaat gtcttttgca taggcagtaa ggtaaggaat gaatcggcgg agcgtctgca
    67381 aggataattt ttttactttc ataactattc ttcctcctgt gatgcgacga tttcctgata
    67441 ttctgctgat tgagcaagta attcttcatg ggtaccctga gcagcaatct taccttgatc
    67501 catcactaag atatgatgtg cttcttgaat agagcggaca cgttgggaga taataatcac
    67561 tgtactgcca agataagtct gtagcgcctt acgcaaatcc aagtctgttt gataatccaa
    67621 cgcacttaaa gagtcatcta aaatcagtaa tgctggcttg gcaatcaaag ctcttgcaat
    67681 cgtcagtcgc tgtttttgtc cgccagagaa atttttccca ttttccatga cttttgtatc
    67741 taaaccattt ggaagctgac ggacaaattc ttctgcctga gcgattttca gagcttccca
    67801 acattctttt tctgtggcgt ctttcttacc ccattgaagg ttttcacgaa tagtcccggt
    67861 aaatagtaca gaagtttggg gaacaagagc aatttgctga cggagatgat ccagctgcca
    67921 agaacgaaca tccattccgt ccattataac tgtaccggaa ctgacatcat agaaacgcgg
    67981 aatcaattgt gtcaaagtcg ttttcccgct tccggttgga ccaatgattc caaggactgt
    68041 atttcgcttc agctgaaatg taatattttg gagagaaaga ccagaatcag gagtataacg
    68101 gaagtcaaca tggtcaaaag cgataattgc ttcagaagaa aaatcgggag tagtactgac
    68161 ctcagcttca agaatcgaat tttctgtgtc tagcacctct ttcacccgat ttcctgaagc
    68221 ttcggcacgt gtgaagatca cgacgaggtt tgaaacaacg atcagtgcca aaagcatttg
    68281 attcatataa ttgatcaaag caagaacttg tccttgttgc aagctaccaa tatttacttt
    68341 gatcccgcca actgtcagca aacagatgat cccgacattc atgatcaagg ttgtagcagg
    68401 tgataatagg gcagagatat tggaaacacg taaataattg ttcgctagat catttgtgct
    68461 tttatcgaac ttctctgttt ctttttttgt ctgcgcaaat gcgcggatga cacgaacacc
    68521 gctaagattc tgactaacgt gttcattgag ctgatctagt ttttcttgca ctttttggta
    68581 gagaggaacg gtttttttga tgataaaaaa taaaatgatt gagaaaatag gcaataatgc
    68641 taagaaaaac agacctactt cccagtcgat cacaaaagcc atgaccactg acccgatact
    68701 taaaaacggt gctctgatca ataaacgaat gaccattgct aaagctagct gaagctgatt
    68761 gatgtcgttt gtcattcggg tgatcaaggt atctgttcca aaatgattca actcgttgtg
    68821 agagaaagta ttgatttttt tgattagctg attacgtaac tctgtaccaa atccttgtga
    68881 agctactgaa gcatagtatt ggcaaatgat agcacaaatc agaccaatca cagacatagc
    68941 gaccatccat aagcccattt caatgatttt tcctcggtca ttcattttta gtccattatc
    69001 gatcaaggaa gccatcatta aaggcaggac aagttcgaag acagcttcaa gaaatttgaa
    69061 gaacgggccc aaaatgattt gcttacgata gtcttttgca taacgtaata actgaatcat
    69121 atgattcctc ctattattta tttgtccaca attgaaaaaa caagtactac cacattgtag
    69181 cttaggaaat ttagaatgaa aagagaacaa gccttttcat aaatgaaagt tttattatga
    69241 agaagcttta gaaattgaat agactatttt ttttaaaaaa aagaaaatga gaaaacatgc
    69301 cagtctcttc attcatagga acgtctattt tacttaattt ttctataaat gaattctgca
    69361 taaaaaatat atcaagtaaa tgtttataga tgaaactcta tttacttctt ttttaatttg
    69421 ttcttgcaat cttttttgct acgtaatttt tgtaaaaaag tgggttgaga gaaatctaat
    69481 tgattttcaa agaaggagta tgaaaatgag aaaaatattt attcgtttat tgtgggtact
    69541 atcttagagg aataaataat agtggagaaa actatggttt ggcgcagatt ctatcaggtt
    69601 tgatggaacg aagacaacct cccgacatca agtcaaaagc cacttgagat tttgatctga
    69661 aaataaaaaa agaaaacaag gtaggaacat caatgtttct accttgtttt cgtaatcaat
    69721 gggaaaaaac taagagtggt gtacgtaatc aataaaaagg atggtgacaa cagtacctct
    69781 ttactctctg aaagcatcat aactcgtttt tcctcattat gccaataaat tgttgttata
    69841 ccacatataa ggatttgtaa tagctaaaaa cagacaggaa agttgaaatc tgtgaatctt
    69901 attttgtatg gaaggattta tagaacgcaa aaatcaagat aaagatgaat aaaaatcctg
    69961 tttcggctat atattgcgta tctacgccaa taaaacgagt ttgttctgtc atagccatat
    70021 aaagcaaagg caaaaataca actacagcga gataagatcc gatgatttct cgaaaagttt
    70081 tccaggaagt atgtttcctg tttttatatt tatccgattt cattgaatag tcatagcctc
    70141 cttattcttt catatgttga aattccagta taaaaactgg aaggaactgt acgtttttta
    70201 gaataaaaat tataagggat aagtaggctg ctgtctataa taagatatat ttttcaattc
    70261 tttattaaag attttattga caaaatgaat ccgttttcta tgatggagga ggggtgaata
    70321 agttgttgaa gaaggaaatt ttatgttact tagagaacca gacagccttt ttcgatttag
    70381 aacatatgaa cgaggtcttt acagcacaaa ggttagctga tcattttggg gtaaaaagaa
    70441 acacagtcag tcattatttg aaccagttaa atgatgagca actactagtc aaaatcaatt
    70501 ctcgaccagt gatttatttc cacaaagaag cttttgaaaa acaatttttt aagttacgca
    70561 cgaattttta tttttctatc gatgatctca aagaggaaca gccttttttc gcgcaaccaa
    70621 aagacttatt ctcttttatg atcggatacg acgccagttt gaaagaaagt atcgaacaaa
    70681 tcaaaacagc tctttactat ccagatggcg gattaccact tttgattaca ggcgaaagtg
    70741 gcacaggtaa aagttattta gttaatttgg tctatcagta ttgtctgctt catgatctgc
    70801 tagaagattc tgcaccattc atcactttta attgtgcaca atatgcagat aatcctgaac
    70861 ttttgactag caatttgttt ggacatgtta agggagcgta cactggtgca gaagaaaata
    70921 aaaaaggggc ttttgaagca gcagatggtg ggatcttgtt tttagacgag gtacatcgct
    70981 taacaccaga aggtcaggaa aaactgttca cctatcttga tcaaggtgtg atttatcgta
    71041 tgggagaacc taatttgtca cgccggatca aaacacgtct cttttttgct acgactgaag
    71101 agattactag tcatttctta acaactttca ttcgaagaat acctatccga atcgaactac
    71161 ctgcacttaa tcagcgtagt cgtaatgaac ggctagaact gatttactct ttttttctcg
    71221 aagaacaaag aaaaatgggg agccctttgt cagtcagtgg accagctttg tcacttttaa
    71281 caagtcagaa attatccgga aacataggag agctgaaaaa tatcgtcaaa gtttcagcag
    71341 caaaagcata tgctgaacag cgtgaacagc ctgaaatcca tgtcacgatc catcatttgc
    71401 aaaaagaact acttgcgcag cctattacta aaaatacagc acagcaagga atctatatta
    71461 cgcaagacca gaccttagag caattaatgg agaagcaaca gcccgaacag cagcgaatcg
    71521 ttaaaagttt tgagcaaatc ctaattgatt tcaagaaaaa taactgtctg ctatattctt
    71581 gcgaaggaaa attaaagcaa gaagtgattc aattatttga ttttttgctg tttgagacca
    71641 gtagacaaga aaaacacgag ctgctggttt attggacaca atctatccga gagacctttc
    71701 gacaaatgga aactgcctat caaatcaaat tcgatggaaa cagtgtctat gccttgagtt
    71761 actatctcta tcagcgaagc actatcaaat ggttaccgga agaacatgat attatccaac
    71821 taatcaaaga attagaacaa caagtttctc agtcttatcc atctagttat cactatgtcc
    71881 aacgaattct ggaattaagt aagatcaaat tagatattga agacacaagt atggatcgga
    71941 ttttactgac gatctatcta aaaaaagcga aatggtcaaa agaaaaacga ctgccaaaag
    72001 cgatgattgc tgctcacggt tatgcaactg ctagcagtat ggcaaatgta gtaaatcgtt
    72061 tattacaaga ggatctattt gaatcatttg atatgccact agatgtcaca ccacagcaga
    72121 ttgcttcaga aatccttgat tattgcgaaa acagcgatgt ttcaaatgga ttgatcatat
    72181 tagtagacat gggatctctg aaagaaatcc atcagttttt taaaaaacag ttatccgtac
    72241 cgcttttgat tttgaataat gtgacgacac ctttagcaat cacagtaggg gaatgcctgc
    72301 aaaaaaatgt atcattagaa gagatagcag aagagactgt tcgacagatc cagccagaat
    72361 ggcgactgct ctatccagag gaaaacaaac ccaaagcact cattactact tgcttcactg
    72421 gaatcggtac ggcggtccac ttaagtgaac tgctagaaaa aagcttacct acggcttgtc
    72481 agttgaaaat catcccatat gaatatcagc aattaaaaga taagaaaaac agtgacccat
    72541 tattttccat atacgaagtc gtaggaatga ttggcaccac agatcctgat atcaccaata
    72601 tcgactatct ttcattagaa gacctcatct cgggggaaaa gatgtctgta ctagctgaat
    72661 ggttggacac tactatgaat gcttcagaga aggaaatatt caatcagcgc atcattcgta
    72721 atttttcatt ggaaaaagta ctggattccg tgactattct agatacagag aaggtgatgg
    72781 gagaaatcga tcattttatg agagaattag aggtgcagtt gaatcgaagc atcagcaatc
    72841 ccaaaaaatt agcgttgtat gtccatgtga gctgtctcat tgaacgattg atccgacaaa
    72901 tgccaatcga aacctatcaa ggattagaga aatggaagca gtgtcaaaaa gaagggttat
    72961 ctgctattaa atctgcgttt agtgtcattg aagagcatta tagtgtcatg atccccaatt
    73021 ctgagattgc ctatatctat gatattttga gtgaagatac agagtttctc tcgatagaag
    73081 aagaattttg aacataagca agttgttgcc actaattttg gcatgcaact tgctttttta
    73141 gtatgtgtaa gtgaaaagag gagatgaaaa agtggataga gaaattatct tagcttccca
    73201 tggaaaattt gcttcaggga tattagattc attagagctg atctatggga aaaatcattc
    73261 tattactgta ttcgattgct atactgatga gaattttgat ttagcggaaa cagtaaggca
    73321 gctttttatg aggtacaaag ataaagaaat cattgttctg acggatcttt ttggcggaag
    73381 tgtcaacaac gaattcttac aatatatcaa tcgggatcat gtctatctcg ttgccggatt
    73441 gaatttgcca ctattgattg agctagtatc tcggttggac gctgaagtag agacaactgt
    73501 tttgatccag caggtgctaa ctgattcaaa aaaaatgatc cagttttgta acgagcggct
    73561 caatcagaaa atagaagaag acgaatttta ggaggaagaa aaatgattgt attgacaaga
    73621 gtcgaccatc ggttattaca cggacaagta gctttttcat ggacacaaac aataggcgca
    73681 gactgtattt tgattgctaa tgatgatgta cctacgaatg agatacgaaa gacaacgatc
    73741 aaattagcca agccacaagg agtcaaacta gtgatcaaat caattgatga ctcgattgcc
    73801 gcgttgaaaa gcggggtgac agataaatat aagttattca tcgtagtgga atcgatcgag
    73861 gatgcatata agctggcaga agcgtatcca gaaatcaaaa ccatcaactt aggagggatc
    73921 aaggcaaaac ctggtactcg cagcatcgga aaagcggtaa atattttacc agaagaggag
    73981 gaacgcttga aacgattaat tgacaaacaa atagaagtag aaatccgtca agtaccagca
    74041 gataaaaaag tggatgtaag agaagttttg taagaaagga agaacctcaa tgattgtaca
    74101 agcagtctta ttaggaattg ttgcatttgt cgcacaatca gaatatgcac tagggacatc
    74161 gttgctttct cgtccgattg tgacggggct gtttacagga atcgtgttag gtgatgtaaa
    74221 aactgggatc attatgggcg caactttaga gttagcattt atcggatcgt tctcagtagg
    74281 tgcttcgatt ccacctgatg ttgtgaccgg tgggatttta gggacggctt ttgctattac
    74341 agctggagcc ggtacagaaa ccgcgctttt actaggtttg ccgattgcta cgttgacatt
    74401 gatattgaaa aatatttact tagggctttt gattccaatt atgaaccata aagcagacaa
    74461 ttatgcagaa gaaggaaatt ataaaggagt cgagcatatg cacttgcttg ccggtatcgg
    74521 tctttccttg atgcttggtg ttgtggtaat ggtttcttat atggtgggaa gcaatacgat
    74581 cggaaatcta ttaaatatga ttcctgactt cgttcaaaag gggttgtcag tagctacagg
    74641 gttgattcca gctcttggtt ttgcgatgct tgctcgtttg ctgatcaaca aacaagttgc
    74701 accatatttt ttcttaggtt ttgctatagc ttcttactta gagattcctg tgaccggagt
    74761 agctattttt ggtgcgattt tagcagttgt ggtagtcaat attatgaatg tccgtcaact
    74821 accacttcaa acaactgcag gggaggtaga agaagatgaa gaattctgag atcaaaaaca
    74881 gcaaaataac gaaaaaagag ctaaatcacg tattttggcg ttcttttcaa atggagtttt
    74941 cttggaatta tgaacgtcag atgaatatgg cttatgttta tgcaatgatt ccgattttga
    75001 aaaagttata tcagtcgaaa gaagaaatgg cagcagcttt gaaacggcat ctagagtttt
    75061 ttaacacgac cccacatatc gttacactga ttttaggaat cacggctgca atggaggaag
    75121 aaaataagga tgatcctgaa tttgatgtga ctgcgatcga tagtatcaaa acatctttga
    75181 tgggacctct tgcagggtta ggagattctt tcttttgggg aactttgcga ttgattgcca
    75241 caggtgtggg tacctcttta gccatgcaag gaaatatttt aggccctatc ttgttcattt
    75301 tgattttcaa tattccgcac attctgtttc gctatctagc aacaggttgg ggatatcgct
    75361 taggaacggg ttttttgaaa aagatccagg caaacggtat gatggaaagt ttgacattag
    75421 gcgcgtctat tattggactg atggtcgttg gagcaatgac tgccacgatg atcaccatca
    75481 atattccttt aaaaatcggt tcaggagaaa atgctgtgac tgttcaaagt atttttgatg
    75541 atatcgttcc aaatatctta tgtcttggag catttggcat agtgttttat ctattgaaga
    75601 aagaagtgaa accattaacg atcttgatcg gactagcttt ctttggaatt tttggttcgt
    75661 ggatagggat tttttaaaaa aggagcagag aaaatgttta cgatgcaaga ttatatctat
    75721 gaagaaaagg aagtactaag tacgatcttg aaaaagaatg atttttcgac aagagaacat
    75781 atgaaaaaaa cagtgaattt actgatctta gcaacgggtt catcttataa cgcttgttta
    75841 gcagcgaagc cagcattgga atcttatggt gatcttactg tcgatattca agaacctttt
    75901 tattttttca attatggaaa actttctcct tcaatcgata ctgtgattgc tgtgtcacaa
    75961 agcgggaaaa gtgcttctac tgttgaagca gtaaaaatga tacaaaaaca agggttacct
    76021 gttgttgcta tcacaaatga cgtgcaaagt ccacttgctt tagaagctgc acaaattatt
    76081 gatttaggtg ccggggtaga atcagtaggc ttcgttacaa aaggctattc tgcgactgtt
    76141 ttacagttac tactcttagg gataggaatt ggaataagta aaaataaaat cagcaaaaaa
    76201 atagaacaag actacatgca acagttgcgc aaaataatca accatttacc agcgattatt
    76261 caaaaaacgg aagaattttt tgatggatat caaagtttat ttcgtttagc acagcgtttc
    76321 gtcaccattg gatatggtcc aaactgggga acagctaaag aagcagagac gaaattgact
    76381 gaaacaatcc gcgttccgtc acaaggattt gagttagaag cttatatgca cggcccatac
    76441 ctggaggcag atgcttcgca tttgctattc tttattgaag gggaaagtgt aaataaggaa
    76501 cgttcgcaaa agttgcaaag atatatgagt cggtacgttg gagagactct caccattacc
    76561 acaaaaaaag caagaaacga gaaaacactt ggattagcaa tagaatgtga tgaatatctg
    76621 tctgtattag cgcttgtcgt tccgtttcaa ctattcgctt ataaaaccgc agtagctaaa
    76681 ggtattgact tgaacaaaaa gatttttgaa gactttgata cagtcttgaa aagtaaatta
    76741 taagaggtgg aaatcatgct gaaattcaat gaagaagaac aaatcaaagc aataaaaggc
    76801 gcactagctt tacgtccgca agtagaagaa atcatcgata aactttatgc ggaaaaattt
    76861 gacgctgtct attatctagg aatcggtgga acgtatgctt cctcgatgca agctgtcact
    76921 tatatgaatg ggaaaagcaa cttgcctgtc tttgtacagc atgctgcaga atattacact
    76981 actggaaaca aaagattaac aaaagattct atcgttattt tgtcctctgt taccggtaca
    77041 actcaagaag tagtgaaagc agtagaacaa atcaagaaag taggagcgac actgattgga
    77101 tttatcgata aagcgaacag taagttgtct cagctatgcg attttgtggt cacttatcca
    77161 gctcctggaa cagaacaaat caaatttttt atggcagcag atcgattgat gtatttgaat
    77221 ggagaattcg aagcttattc agaatactat gaacagctcg aacgttattt accaacaggg
    77281 ttagtggaag cagagaaaaa agcagatgca tttggcttat catttgcaga aaaacatcga
    77341 cgtgatagta tgcattattt tattggagca gggaatcaat ggggagctgt ttattcatat
    77401 gccatgtgtt actgggaaga acaaagctgg cttccatcga aatctatcca tgctgccgag
    77461 tttcttcacg ggacgttaga gatcgtagaa gaaacaaccc cagtcacatt atttttaggc
    77521 gaagatgaac agagagtgtt atctgaacgt gtggctaaac ttttgccaaa aatttgcagc
    77581 aattatacat tgatagacac aaaagactat ccagtagaag gtatcagtga aaaatatcgc
    77641 ggacgtgttt tgtctttctt attgatgcat gtagtgacac aacgcatcga tgctcatgtg
    77701 gagcagttga actgccatcc attagagata cgccgctact atcgtcagtt tgattattag
    77761 gatagactgg ataaaaagaa tataaaaaat aaagagagca gcgataactg ctccctttat
    77821 ttttttaaaa tattggcatc aattacgtta taaaacacat tttttgcatt atctacagtt
    77881 caacttataa tctgtttaat gggacatgtg ggtgccaacc attttttgtt atgcaatagt
    77941 actatttagt tgttgcatgg atccgtagta aaagtccaag tacaacgagt tgcgccagtt
    78001 tacatagcgt tttgtatcca gaatgttgac taaaacaaaa gttcctatgt caaccgtcaa
    78061 cagagacaat ctgtccgttg caggacctga cagatttaga aatgttcaat ctgtctctta
    78121 tgtattttaa atcaatactc actaggagaa gtttcctaac ctcctaatag taatgctggt
    78181 agtaacattg tcaaaactgc ttcctcttag gaacaagcaa agcataacga gtgtaaaaat
    78241 aaaatgtaga ctattgtaac atatcattga ttatttcaag taaaaacgat aaaagaagta
    78301 aacaaacact taaaaacaat ggaaattagt cccaacttta agaaatgtat actataatgg
    78361 aaattatcaa ttatttattt ggaggaatat ccatgaaaca aaaaatcgca gttcttggtc
    78421 ctggatcttg gggcactgct ttagcacaaa cattggcaga aaacgggcat gatgtccgta
    78481 tttggggaaa tgtacctgaa cagattgatg aaatcaataa gtatcataca aatcagcatt
    78541 ttttacctga tttgacgatc ccagaatcga ttatcggata taaagaattg gcagaagcag
    78601 tggataacgc agatgctatt ttatttgttg ttccaacaaa agcgattcgt tcagtcgcac
    78661 aggaacttat tggtaaaatg aatactaagc caatcattat acatgcaagt aaaggactag
    78721 aacaagatac gcataaacga atctcagaag ttttggctga agaaattcca gaagaaaaaa
    78781 gacaggcaat tgttgtatta tctggtccta gccatgctga ggaagtggca gtacatgata
    78841 tcacaacaat tacagctgca agtattgatc aaaaagcagc agcctatgta caaaaactgt
    78901 tcatgaatga ttatttcagg atttatacaa ataatgatgt gattggcgta gaaactggtg
    78961 cagcactgaa aaatatcatt gcaattggtg ccggcgctat ccatggatta ggattcggag
    79021 atgatgcaaa agcagcaatc atgactcgag gattggcaga aatcagccgt cttggtgtcg
    79081 cgatgggtgc caatcctctg acatttatcg gtttgagtgg tgtgggggac ttgatcgtta
    79141 cttgtacaag tgttcattct cgcaattggc gtgccggtaa cttgttagga cagggacata
    79201 agctggaaga agttctagaa aacatgggaa tggtcgttga gggtgtggca acgacaaaag
    79261 cagcagtaga gctagctcaa cagctaggtg ttgagatgcc aattactcaa acaatctata
    79321 atgttttgta taatggagaa gatatcaaaa aagcagcaaa agaaatcatg ttacgtgacg
    79381 gaaaaatgga gaatgaattt tctcttcgtt aaatagatga tcaatagtta atcgtcgttt
    79441 aggaggaaca gcaagtgaag gtcaaaaaag cagtcattcc tgccgctggg ctaggaacac
    79501 gttttttgcc ggcaacaaaa gccatggcaa aagaaatgct tccaatcgtg gataaaccaa
    79561 cgatccagtt tattgtggaa gaagcattgg attcgggaat cgaagacatc ttgatcgtaa
    79621 cgggaaaaga aaaaagaccc attgaagatc actttgatgc aaatatcgaa ttggaaaaca
    79681 atttgcggga aaaggaaaaa acagaattac tcgctttagt tgaagaaacg actcaagtca
    79741 atcttcactt catccgtcaa tctcatccaa gaggactggg ggatgccgtg cttcaagcaa
    79801 aagcatttat aggaaatgaa ccgtttgtcg tcatgctggg ggatgatttg atgaaagatg
    79861 atatcccatt gactcaacaa ttgatgatgg attatgaaga aacacaagct tccgctgttg
    79921 ccgtcatgcg tgtaccagaa aatgaaacat ctaaatacgg aattattgat cctaaaacag
    79981 atagcgaaaa gggtcgttgc agagtaaaag ggtttgtaga aaaacctgaa atgggaaaag
    80041 caccaagtaa tttagccatt atcggacgtt atctactgac tcctaaaata tttgagatat
    80101 tagaaactca agaaccagga gcaggaaacg agatacagct aacggatgca cttcagactc
    80161 ttaaccagac agaggcggtc tatgcgagag agtttaaagg aaaaagatac gacgtaggcg
    80221 ataagttagg atatatgaag acaaatattg aatatggact tcaacattcg gaaattggga
    80281 cttcattaag tgcatatatt atccagttga gtaaaaagct aagaacagaa agttaactgg
    80341 aaataagtgg cctgctgaga atgaaaggct atttgttatt aaagcggcag cttgtgcgtc
    80401 atttgcgcaa ctgtcgtttt agttttttga ctctagatca gttgagtcgt ggaaaacgaa
    80461 agatagaaaa agactttcgt gaatagattc agaaaatatt atgctaatgg tttaattttt
    80521 ttttaagttg tataaaagaa aatgattaca taagagaaat gaaagccaag ccagaagatt
    80581 catagtagaa taaaaaggcg aattttttaa ttataaaaaa aggtgtgtgt tcactatggg
    80641 aaaattagtc gctgttgcac agtcgctgct tgatatactc aagtggctga tggaaggaag
    80701 caattggata tttgtgttgc cactattgct tattagtcta tttatcatgt ttcgcatggt
    80761 cagaaaaaaa gaaacgtttc tgatttttat ctggtatgca gcatccgttg gggttgctac
    80821 cttgatggtt gaattggcgt taggtagttg ggaagcttgc gtatttgctt tattttttgc
    80881 tgtactgtat ctaatcattt atatcccata tatgaaaaga aagtctcgga taggcagaaa
    80941 aggtagacat acaactactt tttctagtac agattctctc gaacaaagta gaagaacgag
    81001 aagaagacgg taatatttag taggtatacg caaaaaaaga taaaataatg gataaactat
    81061 tgagatgaga gatttattta attggtggaa aaaagctttt ttcacttata taaaagaatc
    81121 ttttttaaag gaatgcttgt tgtatcggga taagccattc ctttttttat gttatttata
    81181 tatatataaa tcataccaat gtttttttgt attttcttgc ttgcacttgg ataagagatt
    81241 acttacaata aattcagata gaaacagctg aataaaaaaa ggctccctga cccttagttg
    81301 gcgctaagaa tcagggaatg accagtcaca cacatacacc ctgaccgatc attttgccat
    81361 agtcaatgca gtgcatcgac ctaatttatt gtacctaatc tagggtgaaa attctacccc
    81421 tatgtagata ttttccatgg tctgcacgtt gttttatttg ctatgtcaag gtattgggcg
    81481 tattcgttca atgccttttt tgtgtttgaa acagcaaaga ccacatgtgt tactgtctaa
    81541 ctactgtttt tttatgtact tccttagatt aggcagctgt ttctattcat gtcaagtata
    81601 gctaggcggg agagataaat gagtttatgt tattttgact attatcacca attggaagag
    81661 aaattaagga tagaagagcc gctgatgctt caagctggca cttggatcgc gaaacaaatt
    81721 aatcaaggtg gtagattgca gatatatgct agccgcacac taagtggtgt agcatttgaa
    81781 ttttgggatc aaaccccgga tcttgtacca agtatattga ttgaaaatcc agccggaggt
    81841 gtctatgaaa cgctagaagg tgcaggacag gcaattattg atcagctttc tgtcaaatca
    81901 gaagacattt ttcttcttct ttcgaatgaa ggaagaaacc cggcaatcat cgaactagct
    81961 cagtggatca aagaaaatgg tcatccatta atcattgtta ctggatttga tttgtcacga
    82021 agtatcaaat cgcaacatag cagtggtttg cgattatttg aatttgctga tttggttttg
    82081 gacaaccacg ccaatttaca tgatgcagtc ttgactttgc caaatctaga tccagcgatc
    82141 tgcggaacag cctctcttgc aacgatcttt ttgctgcagc aagttttgta ttttacagca
    82201 aaacagctag tccaggacac aagtggaaaa tagttatcca catgttgaca aagttcctta
    82261 aaaaaataat gttccacata aaaatggagc gtttgaaaaa aagaaaacga ttattaatga
    82321 ggattaacaa cgactacttt ttttgtttta gttattttaa gatggatcat ctttgatttt
    82381 aagcttgttt tgtttaaagt ttgttatttt tataagttgt ttcacagtta tgagaaatga
    82441 gttataagaa tatgtagtgt cagaaaaata aaaagtagtg gaaaaagaga caagaaagaa
    82501 tccatatgga ttctttcttg tctcttaata cacgttgatg aaagagtctt ccccaaaact
    82561 ctttacaaag taattatagt acatttgtta tcattattgc aatgaagttt acctgatata
    82621 acaaaattgt ccaacaggat acctttttct aatagaaata aaatacacaa aaattgaagg
    82681 atagataatg gatatttata agtgtttatt attttttttg caatgaaatt caatttttca
    82741 atgattgtaa aatgaaaaaa acaggacgag attttctcta atctaaaaat aaaaaaagaa
    82801 ttttaaggaa aaacagagaa ataaaatact taatataaat ggaaagagaa aaaaataatc
    82861 atacatagga gaaaaaaaac aaaatagaaa aaagtgattt tctaataaat tattcatgtg
    82921 gaaatgtcat ttttactgta taattcattt gattatccat tttttattca tcaaaattac
    82981 tgaaaaaaga aaggaagaaa taaatttgaa gaaaacaaat tcttcaggaa aaccgaaacg
    83041 cgacttcact aaattatcga caccccatac gtatgtcatt atttttggtg tagtcatctt
    83101 tgcatggata ctgacttttg tcgttccagc aggaaagttc agcacgcaag atattgaata
    83161 caaagatgca aatggcgaaa caagtactcg tactgtttta cgtcaagatt ccttccgtta
    83221 tgcttacgag ctggataagt cgtatgtgtt tgatcaatta gaagaactgc aagatcatcc
    83281 agcagaacgt gaaaaactgg atgttccgga aaaaggattg gaaaaagtca ttgctgacgg
    83341 agaaaaaaat cttacgcagg aaaaactaga tgaaatctcc ttgacagatg atgtgcttta
    83401 cgatcagtac ggcgaaaata tctatgatac ttctaaaaaa ttgcataaaa cagccaaaat
    83461 atggggaaca gatgattttg gcggctttgg tttcttaaat tttgtttttg aaggactagt
    83521 atctggagat aagtatggat ctgctgtagg gatcgctgca ttgatccttg ttgttggagg
    83581 tgcttttggt attattatgc gtaccggagc gatcgacgca ggtatctatg cgtttatcag
    83641 taaaactaag ggactggagc gtttagcttt accgctatta ttctttgctt tttcattcgg
    83701 tggcgctaca ttcgggatgg cagaagaggt aattccattc tcaatggtga tggttccatt
    83761 tgtcattgcg ttaggatatg actcgatcgt agcagtaacc gtgacttatg tcgcatctca
    83821 agtcggaaat gcgacctctt ggatgagccc gtttagcgta gcggtggctc aagggattgc
    83881 tggaatcccc gtgttgtctg gtgcgacatt ccgattgatt atgtgggtag ttgttactgc
    83941 attagccgct ggttatatga tgatatatgc agaaaaaatc cgtaaaaaac cagaaagttc
    84001 gttgacttac aaatcagatg attatttccg ttctcatatc aaaaagacat ctgatgaaaa
    84061 taaaaaattc atgcttgggc ataaattgat cttattagag atgttagttg tccttgtctg
    84121 gatcgtttgg ggcgtgactc aaaaaggcta ttacattcca gaaatcgctt ctcaattctt
    84181 tgtgatggga ttagttgctg gaatcattgc tgttcttttc aaattagatg gaatgaaagt
    84241 caatgacatc gcttcttctt tccaatctgg tgcagctgat ttagctggta cagcaatcgt
    84301 agtaggtatg gccaaaggga ttcttcttgt cttgggagga tctgatgcat ctgttccttc
    84361 agctttgaat acgattttgc atgggatcgg gacggcgttg accggtgttc cagctgtcat
    84421 tggtgcttgg gcgatgtaca tcttccaaag tttgttcaac ttggttgtta catcaaattc
    84481 aggacaagca gctttgacta tgccaatcat ggctccactg gcagatttag taggtgtatc
    84541 cagacaagta gcagttcttg cttatcagct tggttcaggt tttatggacg cttttacacc
    84601 cgtatcagcc agcttgattg gtgtgctagg tgttgcacgg atcgaatggg caaaatgggc
    84661 aagattccaa atcaagatgc aaggattcct gtttgtttta ggaactattt tcatcatgat
    84721 tgccattgca ataggtctgc agtagtactg gagacctgta aataaaaaag taatccaaac
    84781 agtagataag gactccaaga accgtcattt tacggtaaaa tcaaaggagt aaagatccta
    84841 tcgtttggat tattttttaa gatcctatca tcagttatac ttaaagaaag aggaaaaatg
    84901 tatgaaaatc attcgacaaa ttgaagtgtt tgcaccagat tacttaggaa aaatggatgt
    84961 actgattgcc ggtgggaaga ttttggctgt agaagaacag ctagaaggcg gctacgaagg
    85021 agtggaagta gaagaacttt caggtgaggg aaaagtacta accccgggtt tcattgactg
    85081 tcatttccat attttaggtg gaggaggaga aggcggttat caaaatcgaa cgccagaagt
    85141 cacattgagc caattgacta cagctggtgt aacgacagtt gtcggttgtt tgggaacaga
    85201 cggagaaggt agagatatga ctgcgttgat cagcaaagcg aaaggtctgg aagcagaagg
    85261 aatatccact tatgtatacg aaggttcgta ccgattgccg gtaaaaacag taacagattc
    85321 tatcatcaaa gactttttga caattgataa aattatcgga atcggagaaa tcgcagtatc
    85381 cgatcaccgt tcttctcagc caagttttga agagttcgct cgtgcagtag cagatgctcg
    85441 tgtaggaggc atgttatccg gaaaagctgg gatcatcaat gtccacttag gcggaggaaa
    85501 aagaaagcta gagctattga cacgaatcgt agaagaaaca gaaattccga tcacacaatt
    85561 tttgcctact catgcaaatc gcacaccaga attatttgaa gcttgcgtgg catttgccaa
    85621 acgtggtggc acgattgact tcactgctag cgaagatcct gatttttggg agaagacaga
    85681 tggtgaagtt cgcttcagca aagcactgaa acgattgatc gaggaagatg tttctttaga
    85741 taatttcacg atgacctcag atggacaagg aagcttgcct tattttgatg aaaacaatca
    85801 tttcctaggg ttaggagtag gaagtgccaa ggcattgcta gtagggatca aagaagctgt
    85861 gcaaaaagaa agtatccctt tggaaatcgc cttacgagct ataaccagta atccagcacg
    85921 tatattgaaa ttggataaaa aaggaaaaat cgaaattggt gctgatgcag atctgtgtat
    85981 cttggataaa gaaacgcttg atattgatac agttatcgct aaaggagaaa taatggtcca
    86041 agaaaaagaa gtcaaagtat gggggacttt cgaaaaaagt ttttaatcaa cagctctaac
    86101 tatctttttt agaaaacgag cgttctgttt gtctgtatct gttgttgatg ttaccctgaa
    86161 ggtagatcaa taaacaaact aagaggagga agcacaatgg cagatttaaa aggacgttct
    86221 aaagatatga aagataaagt agtcggtgaa ggaaaagaag catacggcaa agcaacagac
    86281 gacaagagca aagaaacaga agggaaagca caatcactag gtgctgacat caaagaaaaa
    86341 gctcgaaatt taggcgacga agtcaaagac aagttttctc gaaaagacga aaaaaaataa
    86401 aaaccactta ttactaattg aatcaagcaa ataaaaaatc cgaaccatat ctgcgagaca
    86461 gatatggttc ggatttttta tttgatcatt atcctgtttt ttaaacttcg attttttgaa
    86521 attttttatt ttttagttca aagacttcat cacagctttt tgctacttca atctcatgag
    86581 tcacgatgat aatacagcga ttttgttcat gggcgatttc ttggaaaagt ttgacgatat
    86641 cttgtgaagt tgtttcatct agatttccag taggctcatc cgctacgatt agttgatgtt
    86701 cacagcagat agcacgaacg atagcgactc gctgctgctg acctcccgaa agtttggtca
    86761 cctgtttttt tgctaatatt tcatcaattc ctacacgagc cagtcgatct aaagcaactt
    86821 gtcgataatt ctcttgcttg gtcttagtga tttccattgc tgctatgacg ttgtctagag
    86881 ccgataaata aggaagcaag ttgtaagctt ggaaaataat cgagacatca tttttacgat
    86941 aacttcttaa cccgattttg ttcagtgaac gatcttgata gtataccttt ccttcttttg
    87001 gtgcatctag tccagaaata agcgaaagaa aagtcgtttt tccagaacca cttgctccta
    87061 aaatagcgta catttttcca gcttcgaaat tcagttctac atctttataa agcgcatctt
    87121 gcggatcttg ataccaaaat cccaattgtt ctgtccgtaa catcaaattc ctcctttagt
    87181 ttaataggat ttttcttggg tttaatctta atatccctat agaagctaaa aagacagaaa
    87241 acagactgat tccaaatgct actccggcta atagtcccaa ttgtgcaggt ttgacattga
    87301 tttccaattc gctgacttga tcagaaacag caaatggatt attcgtggtt ccttgttgac
    87361 catcgcgttg accgccttgt tcttgtctgt tacctggcat ttgtccaccg ccaggagctt
    87421 gctggttttg tgtcgtggtt tctgtctgtt ggtcaagtag ctgctgtccc acggcattcg
    87481 cgacgacgtt tccgctaagc gaagcaactc ctaatgcaag aatcatacaa atagccactt
    87541 cggtaaacaa ttggagaatg attttacttc tggattctcc taaagatagc aagacgccta
    87601 actcatgccg acgctcccga atggtaatca taatgatcag agtaagtatg ataataccgg
    87661 ctacagccac tagtaaaaca acatttttag aaaaacttgc cacgttgttt aaaggttcca
    87721 acattgactg atacatggaa tcatttgatt gtaagctaaa tgtatctgtg tcgatcagct
    87781 tctcagcttc tttgagaaac tcatccattt tatctggatc agatagagtg taaatagcag
    87841 aatctatcgt gttatcgtca gatgtcccat ttagttcatt tgcaaaagtg taagaagtgt
    87901 aaagtgtatt cgacggattc atgaagttga atttcatacc catactgccg cttgtttcgc
    87961 tggattcata aattcctttg atcgtcattt cataagtggt atcttcatct tcagtactcg
    88021 tgattgtgaa agtatctccg actgccaggt catttgtttc tgctagagta gaatcaatga
    88081 ctacattgtt tgtgcctttg tcgctgtcat ctattccttc accatccgtg atttttgctg
    88141 ttccatcaga aaaattacta ttttgtgcag ttgctgacac accactgatt tgaaagtctg
    88201 cttgagtcat ttgcggattc ccgcccattc ctccagcagg ttcaccgcct gcatcagtag
    88261 tttctgaact gtcttcactt gaatcagaac tagtgatggc agttattcca tcttttgcca
    88321 tagctgaggc ggaactttca aaggaataac tctttacatt atctaattca gctatttttt
    88381 ccgcgtccgt taaggaaact ggtgtaagag aaaaactgcc tggatctgga cgttcttcag
    88441 tggtagaacc gcttgaagaa gtttgttcct gttttttaaa tgaagcttct cgattggcac
    88501 ttaaagtcac tgttgctcca acttcttttt gtgcttgatt cgctgcttct tctgcagcgc
    88561 ttcgaatcgt gaggccagct agcacaaaaa taagaatggc tgtgaacacg gcaaacaata
    88621 acaatgaacg tccccatttt acttttgtac ttttccatgc acgtttcata aaattcatat
    88681 tttgcatccc tcctagtaga tgcatttgat aatagacaac ctatcttaaa gctagcttaa
    88741 atcttatgct gtttgcacac catcaacatg aggttctgta tatataaaaa gtcactatag
    88801 ttattgcaaa aaatgtggta aaatgaaaaa agtatgtttc aaaccgacga agaagaaatg
    88861 aaagaggaat agcaaaagaa atcctagatg ctacagaggg atttttacgt gcatagttgt
    88921 tctaacaatt gctgatacta gcgatttagt ttatttgttg tataataatg gggaacagct
    88981 gaatacttat ataagtattc tggctatagc gtttcgcaaa agatccattt tgttaatgaa
    89041 gtatatccaa aataaaatgc ccatccaact gtcagaacgc ggatgtgctg gtaattttcc
    89101 tgctgattct ccataagttg agaaatagtg attttgcata tgcttcattg gaatggctca
    89161 tatatttaga taaagaagaa aatcgacatc tttaaacttg gatgtcataa gaagaggtga
    89221 agtttgtgag taccattaaa attatcccat taggcggcgt tcgtgaaaat ggaaaaaaca
    89281 tgtatgtcgc agaagtgggc gaggatattt ttattttaga ttgtgggcta aaatatcctg
    89341 aaaatgagtt gttggggatc gacgtcgtaa tccctgattt tacgtattta gaagaaaaca
    89401 ttgatcgtgt agctggtgtc tttttaacac atggacatgc agatgcgatc ggggcacttc
    89461 cttacttgtt gtcaaaaatt tctgtaccag tattcgggac agagttgacg atcgagttag
    89521 caaaattgaa tgtcagtcgt aatgaagcag ccaaaggatt taaggatttc catgtggtag
    89581 atgagcatac agaaatagac tttggtgaaa cagtagtgag ctttttccgt accactcata
    89641 cgataccaga ttcagtgggg atcaatctga aaacaaaaga aggtagtatc gtttatacgg
    89701 gagattttaa atttgaccaa acggctatcc caatgtatca aacagattat gcacgattgg
    89761 cggaaatcgg caaagaagga gtcttagcct tactaagtga atcggcaaat gcagaaaatc
    89821 ctcagcctgt agcttctgaa gcccaaatag cagatgaagt atttgatacg atcaaatatt
    89881 gggaagggcg tatcatcgtc gcttgtgtag caagtaattt gcaacgagtg caacaagtat
    89941 tggatgcagc agaaaaagca caacgaaaag ttgtcttgac tggtcaagat ttcgaacgaa
    90001 ttattcgcac agcgatgcgt ttagaaaaac ttcaattacc aagtgaagat ctgcttgtta
    90061 cgttgaaaga catgaaaaac tatgatccag aagaactgat cattttagaa actggccgaa
    90121 tgggtgaacc catcaagtct ctgcaaaaaa tggcaaacgg tacacaccgt aatgtcaaga
    90181 ttgaagaagg agatttggtt tatatcacta ctacgccaag catcgcgatg gaaaccatcg
    90241 tggcgaaaac ggaagatatc atttatcgag ctggtggaac agtgaagttg atctctgaga
    90301 atatgcgcgt ttctggccat gccaatccta atgacttgca attaatgatc aatttgatga
    90361 aaccaacata ttttgtgcca gttcaaggag agtatcgtga attagctgct catgcagatt
    90421 tggctcatgc agtagggatg ccatacaaaa atatctatat tactggacgc ggagacgtgc
    90481 tggaatataa gaacaagcgt atgagtgttg caggaactac aagtgcagaa aatgtaatga
    90541 ttgatggatt aggcataggt gatatcggaa acattgtttt acgtgatcga aaaatcttgt
    90601 cagaagacgg gattttcgta gcggttgtca ctatcagtcg gcgagaaaag aaaatcattt
    90661 caaaacctca aattacttca cggggattcg tttacgtaaa agctagccgt gatctgatga
    90721 aagaaagcag caatatgatt gaaacaatcg ttgagaaaca tttagaaagc aatgattttg
    90781 agtggagcaa attaaagcaa gacatccgag atcaattagg ccgttactta tttgaacaaa
    90841 caaaacgccg cccagtgatc ttgccagtca ttatggaagc tactcaacgt cgaaataaaa
    90901 aataaacaaa aagagtaaga tgaacctctc tatagagtgc tcgtcttgct ctttttttgc
    90961 gaaaaacaaa taatttttga atacagcatc cctcgcttta taataaacga tagaataaag
    91021 ggagtgaatc aatgatgagt caaacaaaag tcgaacgtta tttagaagaa caaaagatca
    91081 gctatcaacc acttgatttt agtcatgtgg tagaagaatc tttcacagaa gaactacaaa
    91141 aaagagggat tgatccagct ttgatatgta aaactctcgt agtgaaagga aacaaaactg
    91201 gggtgatcat cgcattgatt cctttgaacg atcacttaga ttacaaaaaa acgagacaag
    91261 tgacgaaaga tcgtaaagtt ggttttcctg gaatggattt tgtattaatg catacaggat
    91321 atccccacgg agcaaacacc cctattggaa taaaactcgc acatcctgat tattgttttt
    91381 tagcagacag ttctttaaaa gaaaaagaag aagtaattgt gtcaagcggt gaaatcggga
    91441 gaagccttcg gataaaagta gccgatttag aaaagatcgt ccatcctatt tacgctgatt
    91501 taattagtta agggacgaga agagaagcta agcagagcag agacctcaaa cttgagatta
    91561 tatctgcttg gtacttggtg catcctgtat tatctgttac aattgctttg tacatactgt
    91621 actatcaatc caatgaaaat atatttagca gctatatttt ttcattgatg tgcaagtgat
    91681 gaaatcgttt ttaataaaaa agatacagag aaaacgcgag gtgtaaaata tgaaaattac
    91741 gtatcatgga cattcctgtt taacaattga aatggaaaat ggccaacgcg tgatgattga
    91801 cccgtttatt acaggaaatc cattgacaga cttaactgca gaagaagtaa agacagattg
    91861 gttgctgatt actcatggtc atagtgacca cataggagat atgattccta ttgcaaaaga
    91921 aaatcaagcc acaattatca gtattgttga gattgctgat tatgcgaaca gcagaggagt
    91981 agattcattc ggtatgaata tcggtggaaa acatgcgttt ccattcggcg tggtaaaatt
    92041 cgtacatgca cagcatagtt caagctatga agtagacggt atcgttcagt atatgggcga
    92101 gcctagcgga attattattc aagcagaagg aaaaacgatt tatcatgcag gggatactgc
    92161 ttatttcagt gatctaggat tgcttgcaga agaattcgat attgatgtcg ctttcttgcc
    92221 gattggcgat aactatacga tggggccaga agatgcagca aaggctgcgc aaacaattcg
    92281 tgccaagaaa gtagttccaa tccattacaa tactttccct gtcattgaac aagatcccga
    92341 atcttttgta gagttactgg aagatagtga aggaaaaata atgagcgtct cggaaacgct
    92401 ggaagtgtag gcagaaaatg gcgacaaaac atgatttgat tttagaatat attgaaagtt
    92461 tacctgttgg caatcgaatt tctgtaagaa gcatcgcaaa agaattgaat gtcagtgaag
    92521 gaacagcgta ccgtgcaatc aaagatgcag aaaatgtcgg actagtttca acaattcaac
    92581 gagtagggac catccgtatc gaacgcaaat taaaaaaaca tattgaacgt ttgacatttg
    92641 gcgaggtcgt caggatcatt gaaggggacg ttttaggcgg ggcggcagga ttagacaagg
    92701 tcttgaataa attcgtcatc ggcgcgatga ctaaacatgc catggaacgc tatattacgc
    92761 caggatcact aatgatcgtc ggcaaccggg cggaagtcca aaaattagca ttggaagatg
    92821 gcgccgcagt attgatcaca ggaggattca atacgactgc tgagattgca aagctagctg
    92881 atgatcttga aatgccgatc ttacgcacct cttatgatac atttacagtc gcaaccatga
    92941 tcaaccgagc gttaagcgac caattgatca aaaaagatat catgcttgtc agtgatatct
    93001 atatgccagc tgaaaagact cattatttgc agcagacaga tacgatttct gattatcagc
    93061 gtttgtcaga agaaacgcag cattcgcgtt ttccagtcgt caaccgccat catcgtttga
    93121 tggggattgt tacggcaaaa gatgttttag ggaaatcgcc aaaccagatc atcgatcggg
    93181 tgatgacgaa agaaccaatc agtgtaaaga aaacaatgag tattgcctct gttagccatc
    93241 aaatgatctg ggatgggcta gaagtcatgc cggtcgtttc cgatgacttg acattggaag
    93301 gcttgattac ccggcaagat gtaatgaaag cgatgcagct tgtccagcga caaccgcaga
    93361 ttgcagatac gatttcggat cagatatctg gaaatatcca tacgattgat actgaccgtg
    93421 aaggaaatcg tttggaaaac cctaagttca aattcgtagt agcaccacaa atggtcaatg
    93481 gcgttggaac catttctttt ggcgtactta gcgaaatcat ttctgatgtc gcacaaaaaa
    93541 caatggtgat gaaccaaaaa cgaaatatct tgattgaaca agtgaaccta cattatttgc
    93601 ggctgatcca attggaaagc gaattagaca ttcgtccacg tgtattggaa atcggcagac
    93661 gttccgctaa actggatatc gaagtgttta ttgaaaacac catcgtttcc aaagcaatcg
    93721 ttgtttgtca agtaatggaa cgttcttaga aagcaggagt gaaatgacag tacagcaaga
    93781 aatagtagat acaataaaaa aatacgataa aatcattatc cacaggcatt tgcgccctga
    93841 tcctgatgca ttaggatcac aagtaggatt agccgaacta ttacgggaaa gtttcccaga
    93901 aaaagaaata cgtcaagtag gtgaaacgat tgaagggctt cgctttttag cagaaatgca
    93961 agaagttgaa gatgtcttct accaaggagc gctagtcatc gtgactgata cagctaattc
    94021 acccagaatc agtgatcaaa gatatcagtt ggcagaaaaa ctgatcaaaa tcgaccatca
    94081 tcccaatgat gacccttatg gagatcttgt gtgggtaaat acaaaagcaa gtagctgtag
    94141 tgagatgatt gcagaatttg ctttgatgtt tcctgaatct ttaaagatga acgttaaggc
    94201 tgcacggtta ctttatgcag gaatcgtcgg agatacaggg cgctttttgt atccctccac
    94261 gacgtcccgt acattagaga ttgcttcgat attgagaaat tatccatttg atgcaagtgc
    94321 tttgaacaga gagattgaac aaatgccgat gaaagtcgct aaactttccg gttatcttta
    94381 tcaaaatatc caggtggatg aaaatggtgc aggaagaata atccttccgc aagaaattct
    94441 tgataaatat ggaatcgatg attcagagac agcttcgatc gtttcacttc ctggagtgat
    94501 tgacgaagtg ctggcttggg ggatttttgt tcagcagcct tcagggtatt accgcgtacg
    94561 tttacgttct aaggggccga tcatcaatga attggctaaa cgccatcatg gaggaggcca
    94621 tccattagca agtggtgcga atgcaaaaga tttagcagaa gtagaggaaa tctataaaga
    94681 gatccaagat atatgccaat cgtataagag cagaaaaaca gaatgatact tcgttcgaaa
    94741 acgtgccttt tgtagtaaaa atcacaaatg tatcttttca agatcttctt tttccgttac
    94801 aatagtgctc actaaagatt ttaaaggaga aagaagatga cattaccaaa ttgcccagaa
    94861 tgtggctcag agtacacata tgaagatcga ggcttgttga tttgcccaga atgcgggaac
    94921 gaatggaaca aagaagaaca agaaactgtc atagaagacg gattagtggt attagatgca
    94981 aatggaaacc gtctgttaga gggcgatagc gtgacagtga ttaaagactt gaaagtaaaa
    95041 ggtgcgtcag gtgccattaa acaaggaaca aaagtcaaga acatccgttt agtagaaggc
    95101 gatcataata tcgattgcaa ggtagaagga tttggaccga tgaaactgaa atcggaattt
    95161 gtgaaaaaga attaaagaat attcaaggtc ttttcacatt cttttcctac tactaatgat
    95221 aaaataaagt aaacgaaaag gagtgaaacg aaaatgtatg gttatggaat gtatggtttt
    95281 ttagatccga catttctttt ggtcattctt ggattagtta tttccggaat tgcgtcagcg
    95341 tacgtcaata gtactttccg aaaatacgat caagtgagaa gcaaaaacaa tgtgactggt
    95401 acacaagcag cacaatatat attacaaagt caacagataa ataatgtcgg tgttcaacaa
    95461 attgccggag atctcacaga taactacaat tcaggtaata agatgttgag tttgtctcaa
    95521 gcaactgcac agtctacttc agttgctgcg ataggtgtag cagctcatga atgcggacat
    95581 gcggtacaag atgcttcggg ttatgtccca ttgaagattc gtgcagcact tgttccagca
    95641 gctaactttg gttcgatgat ttcgttcccc ttgattatgg taggtgtatt gcttagctgg
    95701 aactctacgt taatcaatat cgggattttc gctttttctt tagcattact tttccaattg
    95761 gtgacattac cagtcgaatt taacgcgtct cggcgagcaa tccaaatttt gagtgaaggc
    95821 ggactactga cggaagaaga agtaccgatg gcaagacacg tattatttgc agcagcactg
    95881 acttatgttg cagcagcgct ttcgacattc ctgcagctgt tgcgcttgat cttattgttc
    95941 ggcggcaacc gaagagatta aaataaagaa gttgtgaaat cagcgctttg atctgagcta
    96001 ataccgagag ttagctgatt gaataccatt tatttggaat aagaggatgt gacaagaatt
    96061 ttgtcacatc ctctttgttt tgttctcata accttttttc atatacagtt catgaaccgc
    96121 ttttattaac ttgccaaata acactgtatt gtgcgttgta tccagataga aagtctccgt
    96181 ttcatctgaa attttctcat gctgatctgt aatgatcaaa tcagcatgtt ctgaatatgc
    96241 ggtaatttta acagcatctt tgcgaaataa ctgctgcaaa tggctttgaa gatgataatt
    96301 tcctgtaaac tgtttggtta tctgcaaatg gatgagtaac tgctctttcg tttctgtttg
    96361 tagtaagtgt tggatcaatt gactaaggta ttgactgatt tggtttcttt ccccattttt
    96421 tgaaaaaatt gtatcgattt tttctcttaa tttcttttcc tgtataaaag aactagaatg
    96481 attggacgtg gcttctggaa agcaaagtgt agaaaaacta ctgctggatt cacccaacag
    96541 ttcgaaaaaa acaactgcca acacaagaaa ataaaaataa attggtattt tattttctaa
    96601 atggttgaga ggaaactgtt gagttaagta agtcatcaat tgaccgactt gtcgacaaat
    96661 aaggtttttg cttgtggaaa ataaaaaacc aatctcctgt ttttgtcgaa aagagatttg
    96721 atttggaaaa aaacaataga aaaaataatt aaagtaggct ctctctgttt ctgtctcttc
    96781 acaagggcga ctcactgaaa aagaagtaaa gtattctgaa taatcatgtg tatgctgcaa
    96841 taagtccatc aattcagtga tttcagaaga agtttttgga aaatatgcct gttgtttgtt
    96901 tcgtaatatg aataaagtta acagcaagta gatatttttt tcttgttttg aaattttttc
    96961 tatttgctca tctgtactgt tcatttttag tgcatttaat tcaagtgagg aaaatggcca
    97021 atcgttacct ccaaatgtat ctgaaagaaa aaagtaaaga tagagacgga tagataactc
    97081 atttccttca agagtacagc aattttttac agataggatc cgtaaatgga attttattaa
    97141 ggaatgattg agctgttttg tcagtttttc gagataggag ggcgatatat aaagttgttc
    97201 aagtaaatat ttttttggta cagcagtttg tggataattg attagtaaca tcaaatagtt
    97261 aaaacgattg gattctttta ggtagcataa ttttaactta gaaaaaacag ctaacttttt
    97321 agtttgatcg gtttctttgg tttggatctc tcctttatga ttagaataaa taaattcatc
    97381 aatcaataaa aattgcttga gtgatacatt tatttttcgg atcagttctt tgattgtccg
    97441 ttttggaata tgtaagtcat tggataattc ttgtaaagaa caattatttt tttgaatgac
    97501 catttgtaga acaagtaact ctttttttct tgcttcaatt agcataaata cctccttttt
    97561 attctgtttt tgtatatagt tagacaaaaa ctgtgagtgg aaagtcattt cagtctgtgt
    97621 tattctcaca gagtgtcgcc ttctttttta tataacgtta tttaattttt ttgttacctt
    97681 gtttattcta ttgtttattt cctagggtat tttgtcaaga tattcttgtt tttaaggcgg
    97741 aaaaattgat ttttaatgga tataactaaa tatgttttga taattatcaa taatattttt
    97801 agaattattt atgttattta tttatgggta gatgaaaaga gacggaggta agaatgatgg
    97861 ggagagtaac aaattatagt aaagaatatt tgctgttcaa aagtatggta tacgtggaag
    97921 aatatggaat gaagtcaatt actgcaagag agttagcaga gttctgcggt tgttctacat
    97981 acccgattta tacacatttc aaatcaatca gcgggttaaa agagaagata ttagaagaaa
    98041 tcactgttta ttttgaaaac tacttagctg aatgcagttc cgatgatgtt ttaagcattg
    98101 tctacttatt gaaagatttt ttttctatcc atgaaagtat tcgtgaaatc attgcaaaat
    98161 ctgatttaga catggattcg ctatttaagc ggccattttt ctcatatgtc aaaggtcaca
    98221 cgaagatcaa agaagaaaag tcgcttgaat tggtatggct taatgcattg ggaagtttgc
    98281 gctcagatga ttcttctcaa gattttcttg aaatgatgaa cgctgtttgg gataaaaacg
    98341 aggtgacgga tgaatacttg gaaaatatct taaaggaaca gtcaccttag gcagcaacat
    98401 gaaaaagtag atcagccacc tttatttttc gtaaaaaaga ttgtaaaatg tctaacgaaa
    98461 cattggaatg aaggaggaag cgacaacgtt accacagcaa tttatcaaaa aatatcgtct
    98521 tcttttaggc gaagaagcat ccgatttttt ttctgcgctt gaacaaggaa gcgtgaaaaa
    98581 aggatttcgg tggaatccac taaaaccggc aggattggac atggtccaaa cttaccatag
    98641 cgaagaatta caacccgctc cctacagcaa tgagggattt cttggcactg tcaatggaaa
    98701 gtctttcctc catcaagctg ggtatgaata tagccaagaa ccaagtgcaa tgatcgttgg
    98761 aacagctgct gcagcaaaac ccggtgaaaa agttttggat ttgtgtgcgg ctcccggtgg
    98821 taaatcaacc caattagctg ctcaaatgaa ggggaaaggg ttattagtga cgaatgagat
    98881 ctttccgaaa cgtgcgaaga ttttatcaga aaatatagaa cgatggggag tttcgaacgc
    98941 aatagtgaca aatcatgcac ccgcagaact tgtccctcat ttttcgggct tttttgatcg
    99001 gatcgtggtt gatgctcctt gttcaggaga aggaatgttc cgaaaagatc caaatgcaat
    99061 aaaagagtgg acagaagaat ctccgctata ctgtcaaaaa cgtcagcaag agattttgtc
    99121 ttcagcaata aaaatgctaa aaaataaagg acaactgatt tattcgactt gtacgtttgc
    99181 accagaagaa aatgaagaga tcattagctg gcttgtagaa aattatccag taacgattga
    99241 ggagattcct ttgactcaat ccgttagttc aggacgttct gaatggggaa gcgtagctgg
    99301 tttggaaaaa acaatacgta tatggcctca taaagatcag ggtgaaggac attttgttgc
    99361 aaagctgact tttcatggac aaaatcagat gcataaagaa aagaagacac gaaaaaaaag
    99421 taaagtgcaa atgacaaaag agcaggaaaa actctggacg gagttttcaa atgattttca
    99481 ttatgaagct actggaagac ttttagtgtt caacgaccat ctttgggaag ttcctgagtt
    99541 agccccttct ctcgatggtt taaaagtcgt acgtacaggt ttgcatttag gagatttcaa
    99601 aaagaatcga tttgaaccta gctatgcatt agcgcttgct acaaaaaaga tagagaatat
    99661 accttgcttg ccgatcactc aaaaggaatg gcaatcttac acagcaggag aaacatttca
    99721 acgtgatggg aatcaaggat gggttttgct agtattagat aagatacctg tcggatttgg
    99781 gaaacaagta aaaggaacag taaagaactt tttccctaaa ggattgagat ttcactgagt
    99841 ggattagttc gtttattttt ttgtctatgc tatgatggag atagataaaa aggagctgat
    99901 acttatgaaa acatcaacaa aagtaacaat cggattaagc gtagcagccg ctgccagtgt
    99961 agcgacagca gtcgttgtat cgggaaaagt aatggaaaag atccatcata tgactactcg
   100021 gacgaaagta aaaaaattcg tctatgacaa atttgatgga aatgaaaaat tactagaaat
   100081 cgtagatggt ctttcagata gtgacttgga ttctttgatg ggaatgttag caaaaatcaa
   100141 atcaggaaaa aagaaaatct ctgtttatgg tgattcaatc aaagattcaa ccgaagatgt
   100201 aaaagaccgg ctaatgcatt ttgttgaaaa aatgatgtaa gagaaactag cttttgaaca
   100261 ctattcattc gaaataaggg gttgtgacaa aattattgtc acaacccctt taatctatct
   100321 ttaattatgt tcatgaagca ataaaagata gcaaaacagt aaatcgttgg ctttttttag
   100381 attgaaacca gactgttctt gaaatttttc gattcgatat tttagagtat tacgatgaag
   100441 aaacagtgtt tttgcagcag agctgacatt gcctaattca ttccataatt cttgaatgat
   100501 cacttccatt tcattttgtt tgatcagttc tatgtaactt ttgatcaact tactatcttt
   100561 tacagtatct tttgtatagt aatgtaaagc cacatcttgc atagaaaaag tacggctgtg
   100621 agtataaaga ttgttttgct ctgttaaaaa aatttttctt tcttcagcaa acaaagggac
   100681 gaggtcggtg ccaggtgaat ggaaagaacc aacgaataca gacgttgtcg tatcaaaatc
   100741 agcatctaaa gatagaaaaa taccgttgat ttcagtagca tcaagataat cacggtttat
   100801 ttgttcgact aagagcgcat ctgtgtctgt ataaaaaaag aaatcagcag aatagcgaaa
   100861 taattccaaa atagtatctt gccattcttt ttttaagaat tctccttttg attcgacgtg
   100921 aagctggatc aaacgaaagc ttttttcttg aacacaagaa gcatctttaa aaagatagtg
   100981 ataccatggg tgtttttttt gatcgttgat tacagggaat aacgctttca aaaggctggt
   101041 ttcttgttga gataatgaat cttgtttgat ccagataaaa gcatcatcaa ttgcaaaaga
   101101 aaggatatcc gcttctgatg ctggagagtt ttttttctgt gcttgtgggt aaagagcaag
   101161 taatttatcc attttcatct tgttcacctc ttgtatttat tttaccatag aaaaaaaagt
   101221 tagttacagc ctttttatca tatgctaaag taaaacaaga aaaaacaaag gcagggaagg
   101281 gtaattggta aatacaaatc ttgatgcagt agaaaaagaa aaatggatgc gccttgcatt
   101341 ggcagaagca aagaaagcag aaatgcttca tgaagttccg attggagcag tggttgtatt
   101401 ggatggaaaa gtgattggaa gaggatataa ccttagagaa accacgcaag atgctactac
   101461 acatgcagaa atgcttgcaa tcaaggaagc ctgtgaaaaa gtgggaagct ggcgcttgga
   101521 agatgctgca ctttttgtta ccttagagcc ttgtcctatg tgcagcggcg cgatgatttt
   101581 gtctcgtgta gcagaagttt atttcggcgc gtatgatcca aaaggcggaa cagccggtac
   101641 cttgatgaat cttttggagg acgagcggtt taaccaccaa gcatatgtag aaggtggcat
   101701 tttagaagac gaatgtggga tgattttgac tgactttttc cgaaagctcc gccagcgaaa
   101761 aaagaaatta aaaaaagact ggtcaacgaa tgaaaaataa ggtatactat tctttgccga
   101821 aaggctagga caatggtggg cttgtgaagc gtgtcaggtc tggaaggaag cagcactaag
   101881 caggttccgc catgtgtctg attataatga aacgacaaca gactttcggg tctgtttttt
   101941 ttatttttat agtactgtaa aaatgaatgt tcctgatttt ttagccagac tgatttatcg
   102001 aatattgtac ttatacaatt tgcttcaagg caggaaaaac tctgaaatag agcttgtttc
   102061 aatggaagaa aaagctgcct atggtatgat aaagataaag agaggcgaga gggtacatgg
   102121 aaaaaatagt gattttacat acgaatgatc tgcattctca tttagaaaat tggccaagga
   102181 tcagaaggtt tttggatcaa cgtaaacgag aaaacgaaaa gaaagaaaaa acgacaacga
   102241 ttgcagtaga tctaggtgat tttgtggatc gttggcatcc attgtcagaa gcaacgaatg
   102301 gacaggaaaa tatcttgctg atgaatgaag ttggttatga tgcagcgacg ataggaaaca
   102361 atgaaggcgt aggaaattcc aaagaagagt tgaatcattt atacgatcat gctgagtttg
   102421 atatcatcct ggataactta ttcgataaaa atacgctcca gccaccggca tggacgaaac
   102481 catataaaat cattacaacg aaacaccaga cgaaaatcgg actaattgca tttactgctc
   102541 catttccgct tacttataat ccgaatggct gggacatacg gaatccttat gatattttgc
   102601 cagaattagt cgaagattta cgttcacaag tggatgtttt agttttgatg agtcatctcg
   102661 ggattcagga tgatttccaa attgcaaaag aaataccagc aattgatgtt attttaggat
   102721 cgcacaccca tcatttattc agagaaggtc acgtaatcaa tgatgtccaa atagcagccg
   102781 ctggaaagta cgggcagtat gtcggtgaag tccatttaac catcgatgaa gagaaaaaaa
   102841 tccttaagca ttcagccaaa gccatcccta ccgaaacaat gacagctttt acagaagatg
   102901 aacaagaaat aaatagttat ctagaacgtg ggcatgaatt attaaaagaa aaagaagtag
   102961 cagatttgcc attttctctg agtctagata tcttcaatga gcattcgttt atccaagtag
   103021 cctttgaggc ggtgaaagaa cgaggaaaga cggaagcagc aatattaaac agtggtctgt
   103081 ttttaactga aattccaaaa gggcgggtca atcaggatca gcttcacact gcgttgccgc
   103141 atccgatgca cttgttaaat gtcacattgg gtggaaatga tctgatccgc ttagttttag
   103201 aaatagaaaa aaatcgtaac tttttacgta actatcctat gaagggaatg ggatttcgcg
   103261 gtaagatttt tgggcagatg gtctataatg gaatcacata tgattctatt aaccatcaag
   103321 tcttttggaa gaacaagcca atcgatctga ataaaaatta tacttttact accgtagatc
   103381 atttgatgtt tgttccattt tttccaacga ttgagattgc tggaaaaaat gaatttttgt
   103441 tccctgaatt tatccgaagt gtggtaggag attacttgaa agctcactac ccaatcaaat
   103501 aaaaacaagg tataataaaa aagataggtg gtgaacgcat gtctgcaaaa caaaatgaac
   103561 agcagaacgt tgagcataaa acagaaattg ctaagaaaaa atcatcagct gaacaggaaa
   103621 caacagtcac cgaagaactg acagctgctt tggaagaaat cgttgaggag cctaaagcag
   103681 aaaaagtcaa aggcgagcta gtgacactgt tagatgacag taattttttg ataggtgaaa
   103741 gacattatcg gcttgtgtcc gattatcgtg aaggatttaa tgcagaaaag cttggagaac
   103801 gttacagtga tgtactagcc cgatatgatt atatcgtagg agattggggt tatgaacaac
   103861 tacgcctaaa aggatttttc caagcggata atcgacgggc gcatccagat cagcgaatcg
   103921 attccttgga agactatctt tacgaatatt gcaattttgg ttgtgcgtat tttgtcatcg
   103981 agagaatcgg cggtaaaaaa gaaaagacaa ctcagcgccg aaaaaagaaa aaaaaccata
   104041 atcgtgcgta tatcgatgag aaaaaaggac cagtcgcatc taatcgcaaa aaaccggtta
   104101 ttaaaaatcg aaaaacagag tcagcaaaaa cctctgaaaa agtaaaaaaa caagaacaac
   104161 ctaaacaagt agaaaaaaca aaaacagcat ttacgatcag aaaaagggaa gagtagtgga
   104221 tgaatggact ataaaggata tttaattgat ttagacggaa cgatttatcg tgggacacaa
   104281 cccataccgg ccggtaaacg atttgtggaa gaattgcaaa aaagaaaatt acctttcttg
   104341 tttgttacca ataacacgac taagtcacca gaaacagtag ctaatcgtct agcagatgag
   104401 tttgacattc atgtagctcc agagacagtc tacacagcta ctttggcaac aatcgatttt
   104461 atgaaagcag atggaaaagg gaaaaaagtc tatgttatcg gagaagcagg attgattgac
   104521 ttgattttag ctgccggatt tacatgggaa gaagaggctc ctgactatgt agtggtaggc
   104581 ttagataatt atctgaccta tgaaaaagta gttaaagcaa cacttgctat tcaaaaaggt
   104641 gctactttca ttggaacgaa cccagataag aatataccta ctgaacgcgg ccttcttcct
   104701 ggagcagggt cagtcatctc ttttgtagag acagcaaccc aaacgccgcc gatctacatc
   104761 ggaaaaccag aagccatcat tatggataaa gccgttgaag tattagggct gcaaaaagaa
   104821 gaagtaatca tggttggaga taactatgaa acagatatcc aagctgggat acgcaataat
   104881 atagatactt tgctcgtttt atcaggtttt acaaaagaag aagatgtacc tgggttgcct
   104941 atcccagcta cctatgtgaa acaatcactg gatgaatgga gcttctaata tgaaaaattc
   105001 gagatggcag tggatggaat atgctggatt gttcagccta tttctgacac tgatcagtct
   105061 ggcagttggt gtgacgatca actttcgacc actatacgta tttgatatcg gacatttgca
   105121 aattttggat tatacttctt tagatcaaga gacgttactg aaaaattttg atcacctaat
   105181 gaattatctc aataatccct tcaaaaccat cctcagcttg ccagatttcc cagtttctgc
   105241 tagcggagcc catcactttt atgaagtgaa aattttgttt ttagtggatt atgctgtgtt
   105301 tttcatcact ttgatcccga gtattttgtt tatcaaatat ttgcaaaaga atgatcggct
   105361 ttggcggttg attcgtccgt ttcaaatcgg catgttactg ccagttgttt tcggtttttt
   105421 catgatgata ggatttgatc gcttttttat cctttttcat gaaacgtttt tcaacaacga
   105481 tgactggtta ttcgatcccg ttactgatcc aatcatcaat gtacttccag aagaattttt
   105541 catgcatagc tttatcttat tttttgtatt attagaatta ttttttgctg tttttctttt
   105601 cttaggaaaa aatagcttga aacaaacaaa aaagaaagaa ctcgtctaaa tagacgtttt
   105661 ctttcttttt ttgttgaatt attgagtaag gcgacttctt ttttctggtt ctttgtgtgc
   105721 taatcgactg gcagcagcag cggcgatcgc tccgacgata tcatctaaga aggtatggac
   105781 atgaacgcca tcgtggctgt ttagttcttt taaaatacca ggtttcacct tgtcgatata
   105841 accataattc gtaaagccga tcgtaccgta aacattcacg attgacaagg ctaggatctc
   105901 atcgataccg taaaggcctt cgtcatcttc gataatatgt tgcaacggac tcatcaattt
   105961 tttcttttct gctaatatat ctaattggat tccagtgata atggcgttat gtacttcacg
   106021 ctttgttagc acgctgttga cactttcagt acaatccgcc aaagtcaaat cagaaatata
   106081 gtctttttgt aaaaacatga caagttgtgc gatatcttct acagttacgc cacgttcctt
   106141 caatagttct cttgcctttt cttctaaagt ctcagttttg acgaccatat tattgctccc
   106201 cctttatttt ttctttctct atttcatgtt aacggaacat gaaaaaaatg caagaaactg
   106261 ctttcgggtt taacttgaaa tgcaaagaga tataaaaaat caactaggac gaagattttt
   106321 atcgtataag cttgtgctgt gaccaggctg agttcgttcc tttggattaa tatagtgtaa
   106381 agcgttgttc actgcagtag gtgcttcacc gagcccagta gcaatcagtt tcacttttcc
   106441 ttcataggta cagatgtcac cagctgcata aacgcctgga atagaagtag acatatctga
   106501 ttttacagta atggcatttc tggtactatc aagtccccaa gaagaaagat gttctaaatt
   106561 agaagagaat ccataattga cgatcagaga atcaatcatc aaatcaatcg tctcgtcact
   106621 tttcactttt tttaaccgga tatctgtcag ttccccatta ttgcctgata atccatcgat
   106681 gagataggga gtaagcaagt tgacagatga agatttcaag cgtgatacac tatgttcgtg
   106741 cgcacgaaat tccgggcgac gatgaatcaa gtaaacttcg cttgcaatag gctctaacat
   106801 caacgtccaa tcgatagcag aatcaccacc tccagcaata gcgacttttt ttccagcata
   106861 cttcatcaaa tcattcacga aataatccaa tccgtggttt tcaaatgatt cagcattatc
   106921 taaattcaat tttcttggct ggaatgaacc atttcctaaa gctaaaatga ctgctttgga
   106981 ataatggatg cctttatttg tagtaatctc gataacttcg tcttcacgag taagcgagag
   107041 aacttcttct tttaaatgga atgtatggtt aaaagtagtt aattgttttt ctaattgatc
   107101 gattaattca cttgctttta ttgctggata cccaggaata tcgtaaatat atttttcggg
   107161 atacaaagtt gctaattgac caccaagttg aggtagactg tcaatgattt ttgttttagc
   107221 ttggcgcatt cctgcgtaaa aagcggcaaa catccctaca ggacctgcac cgatgattgt
   107281 aatgtcatag atttccataa aaattcctcc cttttcacac tatatcagaa tttaattgag
   107341 aatgcttctc aaaaatgttt gaattcgaaa tcgaaacggt aagttataga atgtatctag
   107401 tgatgaaaaa taaaagaaaa caaatctagt atttttacga gaggttaggt attatgttat
   107461 tattattatg aagtatgcaa at
//
LOCUS       DASHXG010000003       100707 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.003, whole genome shotgun sequence.
ACCESSION   DASHXG010000003 DASHXG010000000
VERSION     DASHXG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.003"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(552..2165)
                     /locus_tag="U2R59_000222"
     CDS             complement(552..2165)
                     /locus_tag="U2R59_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8964651.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="U2R59_000223"
     CDS             complement(2306..3214)
                     /locus_tag="U2R59_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8964652.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="U2R59_000224"
     CDS             3397..4521
                     /locus_tag="U2R59_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8964653.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYFENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="U2R59_000225"
     CDS             4748..5665
                     /locus_tag="U2R59_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8964654.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="U2R59_000226"
     CDS             5658..6491
                     /locus_tag="U2R59_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8964655.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="U2R59_000227"
     CDS             6574..7692
                     /locus_tag="U2R59_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8964656.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="U2R59_000228"
     CDS             7686..9584
                     /locus_tag="U2R59_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HEM8964657.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="U2R59_000229"
     CDS             9578..10801
                     /locus_tag="U2R59_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8964658.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="U2R59_000230"
     CDS             complement(10887..12821)
                     /locus_tag="U2R59_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8964659.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRYVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="U2R59_000231"
     CDS             13047..13703
                     /locus_tag="U2R59_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEM8964660.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="U2R59_000232"
     CDS             complement(13777..14130)
                     /locus_tag="U2R59_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEM8964661.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="U2R59_000233"
     CDS             14322..15251
                     /locus_tag="U2R59_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEM8964662.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="U2R59_000234"
     CDS             15262..16098
                     /locus_tag="U2R59_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEM8964663.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="U2R59_000235"
     CDS             16346..17122
                     /locus_tag="U2R59_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8964664.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="U2R59_000236"
     CDS             17298..18041
                     /locus_tag="U2R59_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964665.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="U2R59_000237"
     CDS             18034..19614
                     /locus_tag="U2R59_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEM8964666.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="U2R59_000238"
     CDS             complement(19865..20344)
                     /locus_tag="U2R59_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEM8964667.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="U2R59_000239"
     CDS             complement(20360..21112)
                     /locus_tag="U2R59_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEM8964668.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="U2R59_000240"
     tRNA            21229..21299
                     /locus_tag="U2R59_000240"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="U2R59_000241"
     CDS             21660..22385
                     /locus_tag="U2R59_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEM8964669.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="U2R59_000242"
     CDS             22640..22906
                     /locus_tag="U2R59_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEM8964670.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="U2R59_000243"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="U2R59_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEM8964671.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="U2R59_000244"
     CDS             23359..23664
                     /locus_tag="U2R59_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEM8964672.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="U2R59_000245"
     CDS             complement(23745..24890)
                     /locus_tag="U2R59_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8964673.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="U2R59_000246"
     CDS             complement(24951..25598)
                     /locus_tag="U2R59_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8964674.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="U2R59_000247"
     CDS             25792..26085
                     /locus_tag="U2R59_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964675.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="U2R59_000248"
     CDS             26129..26440
                     /locus_tag="U2R59_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964676.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="U2R59_000249"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="U2R59_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="U2R59_000250"
     CDS             27202..27360
                     /locus_tag="U2R59_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964677.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="U2R59_000251"
     CDS             27361..27723
                     /locus_tag="U2R59_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964678.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="U2R59_000252"
     CDS             27760..28608
                     /locus_tag="U2R59_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEM8964679.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="U2R59_000253"
     CDS             28598..30073
                     /locus_tag="U2R59_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEM8964680.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="U2R59_000254"
     CDS             30339..30746
                     /locus_tag="U2R59_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HEM8964681.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="U2R59_000255"
     CDS             30749..30964
                     /locus_tag="U2R59_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964682.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="U2R59_000256"
     CDS             30968..31348
                     /locus_tag="U2R59_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8964683.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="U2R59_000257"
     CDS             31482..31637
                     /locus_tag="U2R59_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEM8964684.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="U2R59_000258"
     CDS             31706..32179
                     /locus_tag="U2R59_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEM8964685.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="U2R59_000259"
     CDS             32176..33870
                     /locus_tag="U2R59_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEM8964686.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="U2R59_000260"
     CDS             33836..34021
                     /locus_tag="U2R59_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964687.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="U2R59_000261"
     CDS             34025..35200
                     /locus_tag="U2R59_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8964688.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="U2R59_000262"
     CDS             35193..36716
                     /locus_tag="U2R59_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEM8964689.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="U2R59_000263"
     CDS             36772..37056
                     /locus_tag="U2R59_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEM8964690.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="U2R59_000264"
     CDS             37043..37378
                     /locus_tag="U2R59_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEM8964691.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="U2R59_000265"
     CDS             37673..38299
                     /locus_tag="U2R59_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964692.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="U2R59_000266"
     CDS             39041..39877
                     /locus_tag="U2R59_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEM8964693.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40372
                     /locus_tag="U2R59_000267"
     CDS             39941..40372
                     /locus_tag="U2R59_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8964694.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40434..41756)
                     /locus_tag="U2R59_000268"
     CDS             complement(40434..41756)
                     /locus_tag="U2R59_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEM8964695.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41910..43550)
                     /locus_tag="U2R59_000269"
     CDS             complement(41910..43550)
                     /locus_tag="U2R59_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HEM8964696.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43883..44353
                     /locus_tag="U2R59_000270"
     CDS             43883..44353
                     /locus_tag="U2R59_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HEM8964697.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44575..45678
                     /locus_tag="U2R59_000271"
     CDS             44575..45678
                     /locus_tag="U2R59_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEM8964698.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45962..46642
                     /locus_tag="U2R59_000272"
     CDS             45962..46642
                     /locus_tag="U2R59_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8964699.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46732..47766
                     /locus_tag="U2R59_000273"
     CDS             46732..47766
                     /locus_tag="U2R59_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEM8964700.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47780..48115
                     /locus_tag="U2R59_000274"
     CDS             47780..48115
                     /locus_tag="U2R59_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964701.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48099..50579
                     /locus_tag="U2R59_000275"
     CDS             48099..50579
                     /locus_tag="U2R59_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964702.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50635..52194
                     /locus_tag="U2R59_000276"
     CDS             50635..52194
                     /locus_tag="U2R59_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964703.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52191..53555
                     /locus_tag="U2R59_000277"
     CDS             52191..53555
                     /locus_tag="U2R59_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8964704.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53726..54796
                     /locus_tag="U2R59_000278"
     CDS             53726..54796
                     /locus_tag="U2R59_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964705.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54811..55479
                     /locus_tag="U2R59_000279"
     CDS             54811..55479
                     /locus_tag="U2R59_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964706.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55499..56077
                     /locus_tag="U2R59_000280"
     CDS             55499..56077
                     /locus_tag="U2R59_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8964707.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56478..57389
                     /locus_tag="U2R59_000281"
     CDS             56478..57389
                     /locus_tag="U2R59_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8964708.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57477..58394)
                     /locus_tag="U2R59_000282"
     CDS             complement(57477..58394)
                     /locus_tag="U2R59_000282"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEM8964709.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58596..59033
                     /gene="zapA"
                     /locus_tag="U2R59_000283"
     CDS             58596..59033
                     /gene="zapA"
                     /locus_tag="U2R59_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEM8964710.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59092..59640
                     /locus_tag="U2R59_000284"
     CDS             59092..59640
                     /locus_tag="U2R59_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEM8964711.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59755..62115
                     /locus_tag="U2R59_000285"
     CDS             59755..62115
                     /locus_tag="U2R59_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEM8964712.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62202..62516
                     /gene="trxA"
                     /locus_tag="U2R59_000286"
     CDS             62202..62516
                     /gene="trxA"
                     /locus_tag="U2R59_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEM8964713.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62698..64476
                     /gene="uvrC"
                     /locus_tag="U2R59_000287"
     CDS             62698..64476
                     /gene="uvrC"
                     /locus_tag="U2R59_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEM8964714.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYREQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64621..65520
                     /locus_tag="U2R59_000288"
     CDS             64621..65520
                     /locus_tag="U2R59_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964715.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65513..66775
                     /locus_tag="U2R59_000289"
     CDS             65513..66775
                     /locus_tag="U2R59_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964716.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66936..68834
                     /locus_tag="U2R59_000290"
     CDS             66936..68834
                     /locus_tag="U2R59_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HEM8964717.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69164..69883)
                     /locus_tag="U2R59_000291"
     CDS             complement(69164..69883)
                     /locus_tag="U2R59_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEM8964718.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70220..70552
                     /locus_tag="U2R59_000292"
     CDS             70220..70552
                     /locus_tag="U2R59_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964719.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70539..72542
                     /locus_tag="U2R59_000293"
     CDS             70539..72542
                     /locus_tag="U2R59_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEM8964720.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72561..73031
                     /locus_tag="U2R59_000294"
     CDS             72561..73031
                     /locus_tag="U2R59_000294"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEM8964721.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73052..73636
                     /locus_tag="U2R59_000295"
     CDS             73052..73636
                     /locus_tag="U2R59_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEM8964722.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73651..74637
                     /locus_tag="U2R59_000296"
     CDS             73651..74637
                     /locus_tag="U2R59_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEM8964723.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74627..74938
                     /locus_tag="U2R59_000297"
     CDS             74627..74938
                     /locus_tag="U2R59_000297"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEM8964724.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74960..76741
                     /locus_tag="U2R59_000298"
     CDS             74960..76741
                     /locus_tag="U2R59_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEM8964725.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76734..78110
                     /locus_tag="U2R59_000299"
     CDS             76734..78110
                     /locus_tag="U2R59_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEM8964726.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78117..78752
                     /locus_tag="U2R59_000300"
     CDS             78117..78752
                     /locus_tag="U2R59_000300"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEM8964727.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78782..80137
                     /locus_tag="U2R59_000301"
     CDS             78782..80137
                     /locus_tag="U2R59_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HEM8964728.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80329..81723)
                     /locus_tag="U2R59_000302"
     CDS             complement(80329..81723)
                     /locus_tag="U2R59_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEM8964729.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81815..82786
                     /locus_tag="U2R59_000303"
     CDS             81815..82786
                     /locus_tag="U2R59_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HEM8964730.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82783..83565
                     /locus_tag="U2R59_000304"
     CDS             82783..83565
                     /locus_tag="U2R59_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HEM8964731.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83734..84105)
                     /locus_tag="U2R59_000305"
     CDS             complement(83734..84105)
                     /locus_tag="U2R59_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8964732.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84239..84682
                     /locus_tag="U2R59_000306"
     CDS             84239..84682
                     /locus_tag="U2R59_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEM8964733.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="U2R59_000307"
     CDS             complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="U2R59_000307"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEM8964734.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85553..86920)
                     /locus_tag="U2R59_000308"
     CDS             complement(85553..86920)
                     /locus_tag="U2R59_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8964735.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86904..87734)
                     /locus_tag="U2R59_000309"
     CDS             complement(86904..87734)
                     /locus_tag="U2R59_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEM8964736.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87897..88334
                     /locus_tag="U2R59_000310"
     CDS             87897..88334
                     /locus_tag="U2R59_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEM8964737.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88410..89030
                     /locus_tag="U2R59_000311"
     CDS             88410..89030
                     /locus_tag="U2R59_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEM8964738.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89219..89725
                     /locus_tag="U2R59_000312"
     CDS             89219..89725
                     /locus_tag="U2R59_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEM8964739.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89742..90641
                     /locus_tag="U2R59_000313"
     CDS             89742..90641
                     /locus_tag="U2R59_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HEM8964740.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90728..91612
                     /locus_tag="U2R59_000314"
     CDS             90728..91612
                     /locus_tag="U2R59_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEM8964741.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91804..91875)
                     /locus_tag="U2R59_000315"
     tRNA            complement(91804..91875)
                     /locus_tag="U2R59_000315"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91840..91842),aa:Arg,seq:ccg)
     gene            91935..93269
                     /gene="rpoN"
                     /locus_tag="U2R59_000316"
     CDS             91935..93269
                     /gene="rpoN"
                     /locus_tag="U2R59_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HEM8964742.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93418..94509
                     /locus_tag="U2R59_000317"
     CDS             93418..94509
                     /locus_tag="U2R59_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HEM8964743.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94550..95551
                     /gene="gap"
                     /locus_tag="U2R59_000318"
     CDS             94550..95551
                     /gene="gap"
                     /locus_tag="U2R59_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEM8964744.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95661..96851
                     /locus_tag="U2R59_000319"
     CDS             95661..96851
                     /locus_tag="U2R59_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEM8964745.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96955..97710
                     /locus_tag="U2R59_000320"
     CDS             96955..97710
                     /locus_tag="U2R59_000320"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEM8964746.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97826..99124
                     /gene="eno"
                     /locus_tag="U2R59_000321"
     CDS             97826..99124
                     /gene="eno"
                     /locus_tag="U2R59_000321"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEM8964747.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99523..100662
                     /locus_tag="U2R59_000322"
     CDS             99523..100662
                     /locus_tag="U2R59_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HEM8964748.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17203 c        20781 g        29318 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatttt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacgtaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cgtcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttggtcaat tgttacaatg cctttgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaggagtata ctgtgataaa
    39901 aaaattcatt taaaaaaata aaaattggct ggtgatttgg atgttgcggg aaatgcgttt
    39961 aggagatgca gaagcactac gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gttgaaggag ccagaaaaaa attttttctt
    40081 ggtctatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttc agcgatccga tgttcaatat tatggcactt gctgtgtcta aacatgctga
    40201 aaaaagagga atcggaaagg ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat
    40261 atcagcaata agacttaatt ctgcagaata cagagtagaa gcacaccgat tttatgaacg
    40321 catcggttat cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatttttat
    40381 caaaaaatac ctggtcatca agccgatact tgatgatcag gtattttttt tgactaagaa
    40441 agtaattgca tcaagaaacc tgagatgatc aaaacgatgg caccaccaag ccgattgccc
    40501 atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacagc tacatttcct
    40561 gtaccaccca tcgagttgtt gcataagcca gcagtaatag ttgattcgat tggatataaa
    40621 ccaaacaaac gaccgacaaa tcctgaaact actgaaatcg cgataacact tgtcaaacat
    40681 aagacaacaa attgccatgt caaagcagaa gccaatacat ttagattcaa taacgcaata
    40741 ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttgtt gaacatgata
    40801 gctgcatctt cgtaatattc tggtaatagg tttgcgattt tacagataac aacgataatg
    40861 atcatgaatg cgtaagcatg gactttagga acaaaatagt tacagatttg tcctaagatg
    40921 aagaaagtca atgataccat caaaccgaca cctaattgtg gaatggaagg ttttacattt
    40981 ctaggttttc catcgccaag gtcgcctttt tccattaatt taccattacc gttgaatttt
    41041 ggcattgatt gtcccgcacg agcaactaac gctgcaccaa tgatagctag gacatttgtc
    41101 attgctgtcg caggaatcag gcgggaaatg atagaagaag cgtccgtacc taaaacattt
    41161 gcataaatcg ttgataaagg tacagctccg gctccaacac caccagccat tgcgggcaat
    41221 gagatatata aaacggaatt tgcaaaacca tttccgataa gcatacctac gagtcctacg
    41281 gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac agaagctttc
    41341 atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc aatataaaag
    41401 tctaaaaagc ccatattgct gacaaagttt tctgtggatt ttactacata ctcaggtaag
    41461 atcccaaatg tagcaatcgc ggcagaggca aagatcgcaa aaacggagcc accacctaaa
    41521 taacttttga cgatagggat ttttgttccg ataaaatgaa ataaattacc gaaaatgacc
    41581 aaaacagcga ttgggccaat catattcgtc ggtaattttc ctaaagccat tgcaatgatc
    41641 aggacaagga ccatgatcaa ataaaggggc aaacttacgc cggtaatttt tgttgaccaa
    41701 aacccttctt ttttcttttc ctcaactgca gttgcggttg ttgttttttg tgccattttt
    41761 acagatcctt tcttattctg tatcgtatga aaaaagccaa agagaagcgg caaaagagca
    41821 gtagttggct ggctgctgtt ttgccgcagt cgcttttttc tttttagacg tcatacaaag
    41881 tttctgtatg ttcttttact ataacaatct taatcttcta aagatttata ttcaggaacc
    41941 catttagcag attcaacagc ttctttgata tccgtgattt cttcacgatt caatttttgt
    42001 gcaacaactg attttgcgac agtttcagca atcgtttgag agaattcagt gatttttgct
    42061 actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc taatgctcga
    42121 ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat caaaccaagc
    42181 cctaaacctg ggtacatcaa cgcattattt gcttgaccga tttggtaagt tacaccgtta
    42241 tattccacat cagcagcagg gatacctgtt ccaactaaag cttttccgtc cgtccattca
    42301 atcaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg catgatgatt
    42361 ggacgtgggg tatgagccgc catttctttc acgatttctt cagtgaatgc tccaggttgg
    42421 gtagaagtac cgatcatgat cgttggatgg attgctttta caactgcttc taagtttgtc
    42481 aattcatcag cattagtgaa ttctgagcgt ttacgagcga atgggatttg accaggagtc
    42541 aatccttttg tatcttcaaa caataaaccc tgtttatcta cttgatagaa atgttggcgt
    42601 gcttcttctt caggtacacc ttgacggatc atttcatcta aaaggatgtt tgcgatacct
    42661 acaccagcag taccagcacc aaatgtcaag atcgtttgat ctttcaattg ctcacctgat
    42721 atattcaatc cacctaatac accagctagt acaacgattc ctgtgccttg gatatcatca
    42781 ttgaaagtag tgattttatc ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca
    42841 aaatcttccc aatgtaataa caattctggg aataattcag tagctgattg aacgaattga
    42901 tcaatgaatt cgtagtaagt ttcgccttct acacgagcat gacgattccc taagtataat
    42961 ggattattca ataattcttc gttattagta ccagcgtcga ttgatacagg caagacttgt
    43021 gcaggattga taccagccgc agcagtgtag accatcaatt taccgatagc gatgtcaaca
    43081 ccgttcacac cccagtcacc catacctaag attccttctg catctgtcac aacgatcaaa
    43141 cgaatgtcgc gtccatctgc tgcgtttttc aaacttgctt tgatattttc tggttcgtcg
    43201 attgaaagaa atgcagcatc ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa
    43261 tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc gcccatcaat
    43321 ttataaaaca atgtccggtt cgtattgaat agattcatta agaagatacg tttttccaaa
    43381 tcggtctgtt tgcttaagta ttgaccgtaa gcttggacag attgttgttc caatgtttgg
    43441 acagtacttg gaagcatacc agtgattccg tattttgccc gttcttcttt tgtaaaagct
    43501 gttcctttat ttagaaaagg attatttaat aagtttagcc ctgtaagcat gaatgattcc
    43561 tcctaagttt taatacaaac gaagtatagg agtcagatga ggatatagtc aaaaagagca
    43621 ggtataataa attttattta tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt
    43681 tgttcttttt atatcaacaa tccttgcttg attactatgc gtatctctta tatgctaaag
    43741 aaagaaaagt agaagaataa aggatatgtt agatagataa atagaatctc tgaagaataa
    43801 atcacgtgat cgtgacgata aaatacactt acgtcaggtg ataaaaaata cataagtaga
    43861 aaactaagag gaggaacaga aaatgaaaga agttcaattg atcagaaaaa gcgaactatc
    43921 agaaggtggt tgcaatgcat gcggcgtagt agaagcaaca agctatacat taaagcttgg
    43981 tgccaacaaa gcgataatct ctgagttgac agtaggcggt cttgtggaca gtctggcgct
    44041 tgctgaaggt tttattggag aagatattta tgagatgttt tcagaaatcc gtcagttaaa
    44101 aaaaggggaa aactgcatag aggttcatca tgagagcccg aatgtgagat tcaaacgtgg
    44161 tgataatgag atgatcttca ataatcatgt gtccgatcac accgagctat atggaatcgt
    44221 gaatcaaata ctaactgagc tttttggatt gggaccttat gcgttcaagg aagaaaacgg
    44281 taatccaaaa ttaaacgaag aatggcaaga aacgattgaa atacaaagaa acaacccgca
    44341 cttatttcaa taggcatcca cagtatttcg taaaagggac tttgacacga cttttgtcaa
    44401 agtcccatcg ttttttatct atttgtgttc taaacatttc tttcagagta gtaacaactg
    44461 gaatgactga aatgtaaaca gattatttgc ctgtatcaat acggaagagt aatataaagt
    44521 gtgtaaacgc tatcatatta ttcattcaat tttttataga gggaaggcat tgaaatggaa
    44581 aaaacgtatc aagcaggtac aaatgaagga atagtggatt ttatcaatat ggaagattta
    44641 gaaatagccg cttcacaagt gattccagct ggtggttatg gttacatcag cagtggtgct
    44701 ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcagct gattattcct
    44761 catgtattaa aagatgtaga attacccgat acaactacac attttgacaa agaaacgctg
    44821 actgcaccaa tcatcatggc accagttgct gctcatggct tagctcatgt gaaggcggag
    44881 aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag ttcttacgct
    44941 tcttgtacat tagaagagat aagagaagca ggcggggaga aagcaccgca atggtttcaa
    45001 ttttatatga gcaaagatga tgggatcaat ttggatattc ttgaagtggc caagcgtaat
    45061 ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg tgaaacagac
    45121 cgcagaaatg ggtttacctt cccactgcca atgccgatcg ttcaggctta tcaatcagga
    45181 gtaggccaaa cgatggatgc tgtgtacaaa tcttccaaac agaagcttag tccaaaagat
    45241 gtagaattta ttgctgctca ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa
    45301 gaagatgtct atcgttcatt agaatctggt gctggcggaa tctgggtatc taatcatggt
    45361 ggccgtcaac tagatggtgg tccagcagcg tttgattcgt tgcaatatgt ggcagaagca
    45421 gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgcggaca gcatgttttc
    45481 aaagcaatcg catcaggtgc agatcttgtt gctattggca gacccgttat ttatggattg
    45541 tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac agaattggaa
    45601 atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt
    45661 gagaatcgtt ttatttaaga aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc
    45721 gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa cgaaaaaata
    45781 aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta aacgatttta
    45841 ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga tgaattcatg
    45901 aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg agtgatttat
    45961 tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag gcggcttggc
    46021 aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct ttactgaacc
    46081 aacaaatacc gtggagcctc ttaaccctac tgatccttca aaaccagtag agccagcaga
    46141 tccggaaaat ccagcaactg gccagacagg tcctttaaca ctggatgtag ttcccgaatt
    46201 gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa
    46261 aaacgataca ccttatctcc aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc
    46321 acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac aagttttgca
    46381 aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata acgaatccac
    46441 tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga caccaatatt
    46501 tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc cagcaaatat
    46561 cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga cttggaacct
    46621 cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg tgaaaatact
    46681 ataggtgaag gattttttac cgcagttttt gttgaaagga tgtggtggac aatgaatcaa
    46741 agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat ttttccgtca
    46801 atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt tccagagaac
    46861 caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca aaatcagaca
    46921 ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt ctctgtcaat
    46981 ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc aacgttagat
    47041 gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta
    47101 tcagcacatg cagaaacaac tgtacctata gaagtgaaaa tcccagcaaa aagctttaag
    47161 ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac agaaaatgct
    47221 acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa
    47281 agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga cgaggtcaac
    47341 gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat cagcaatttg
    47401 atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac gtctaatgca
    47461 tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg tgataaagca
    47521 aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa tgaatggcga
    47581 tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt
    47641 tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc tgcagttcta
    47701 gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca
    47761 acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta ttgcaagttt
    47821 gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag gtacgattac
    47881 attttatgat ctaagtccaa ttccgcatcc aagtggttca gtcaatggcg catcaaaaca
    47941 gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc cggagacgaa
    48001 tgaacaaaag atccgttttc tttatttgat cattggtata gaattatggc ttcttgcgtg
    48061 gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa aataaatttt
    48121 cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt atcttttcac
    48181 cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca tacacgtatg
    48241 aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac
    48301 taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat ggttcaaatg
    48361 atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg
    48421 tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc atcaatttgc
    48481 cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac gcctacttgt
    48541 atattgccgg tgcccccatc aaggttacta gcggaagttt attatcagca ggaagccata
    48601 ccttgcgttt tgggatgggg tcgtgggata caaatactct attgacagat attattgcta
    48661 ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat gttacagcta
    48721 atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac aaaattttga
    48781 ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt gatttttatg
    48841 attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca gctgcaggta
    48901 gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca ttttctgcaa
    48961 gtgcagagat aaatacgtgg aatagttaca tctcaccaag tgattcaaca ggaaaatata
    49021 atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt ccaggctcta
    49081 ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag ttgccattta
    49141 gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa ggagcaatac
    49201 tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc gtgtacagtg
    49261 ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg gagcagtaca
    49321 agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg ggaaagctcc
    49381 tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta aaaaagggtt
    49441 cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga tggacagatc
    49501 aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact tctacactac
    49561 ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat gtacttacta
    49621 acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc accactcttc
    49681 ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta aaaaacctta
    49741 gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg attcaagaaa
    49801 atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa atcacgatct
    49861 cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt acaactatcg
    49921 cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc aaaataggag
    49981 ataccattca tcttacttac aactatcaat taaatactgt agatacttct ttacaatccg
    50041 tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca gatggtgcta
    50101 agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc aaacaagaat
    50161 taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc aaaccgttga
    50221 agacaagtta ttatgaatca aaaggcgatt tttcttttga tgtgcgggat actcggcttc
    50281 caagcacgtc tccttggcaa ctgacaggta cattgacttc tttatttaag aatgatcaag
    50341 gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaag caattgattc
    50401 agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga gaggttctcg
    50461 ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg aatgctcaac
    50521 ctggcgcaac gtatcaaggc atggtcacat ggaaactgac agctgggcca accagctaag
    50581 tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc aaggatgaga
    50641 aggaaacttc tgctgttaaa atcagaaatg cttgaaggag tggacttgga acttttcagt
    50701 ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt agaggaaaaa
    50761 ggagaggttt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc taccttgaaa
    50821 gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga aattgttatc
    50881 caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga tgtttattat
    50941 cattgttact tgcgctattc tacaaaatat cagatacttc tttatctgtt ggaaaatggc
    51001 tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac tttgtctcgc
    51061 agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg
    51121 ctgaccggtc cagaaagtca aattcgttat ttttatttcc aattattttg gtttggacgt
    51181 ccctatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt tttagatctg
    51241 ctgcaaaaag agtttagttt tgctattaca gaagaaggac gattgaaatt tgaaatatgg
    51301 ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat
    51361 cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac atttttgacc
    51421 cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt tttttatctt
    51481 ttcatgatca gtaactttac attagataca cataactcgc atgtccagga gtttttgata
    51541 agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa acaatcgata
    51601 gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat tgcgttgaca
    51661 gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat ttttggccaa
    51721 gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt tttatgtgaa
    51781 agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga ggaaaatgcc
    51841 cgctttgaat tatttgctcg ctatgcatct attttacgga cgctgatcaa gcagttagaa
    51901 ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa
    51961 gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga atacgagaaa
    52021 gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc acagaagtcc
    52081 gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta tttgaaccaa
    52141 tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac atgaaaatcg
    52201 tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga aaacttcaac
    52261 cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc tatgtttcaa
    52321 atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt gcccataaca
    52381 tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta actgaacttg
    52441 atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag accataacct
    52501 atgataaatt aatcgtagcg acaggttcct ctcctgtcac cttgtataaa caaattgaag
    52561 ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt gccgctttaa
    52621 aagaagcaaa agaagtagtg atcttcggtg ctggttacat tggattggaa ttagcagatg
    52681 ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat gttttatcaa
    52741 gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact aagcaaataa
    52801 atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg
    52861 tacaacttct gtctcaaaca ataaaggcag atatggtcat tttttctgcc caaactcgtc
    52921 ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact gtgatagtca
    52981 atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc gtcccagtca
    53041 gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct gtacatatgg
    53101 caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc agacaaaaga
    53161 taacagcagc agtcattata gactactttt taggaactgt agggctgaca gaagatgaag
    53221 cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta tttccacaat
    53281 acgacgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat acattagaaa
    53341 taattggcgg acagctgata agccaagaat tcttattatc agatttgaac ctgcttgcgg
    53401 atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt ggatttctgt
    53461 ctgaatacac ctctcgtttt cactacctca atgagttagc ttttaaagta ctagctaaga
    53521 gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct tttattgtgt
    53581 ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga aatagcggaa
    53641 gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa
    53701 tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta tgcattcaaa
    53761 gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg tatttttttt
    53821 gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca agtgggaggc
    53881 agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca tgattactaa
    53941 gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaaa cacctggagt
    54001 cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct tcggtatcga
    54061 taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata acgatgatga
    54121 ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccataggag atacagttaa
    54181 gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg ccaaattcaa
    54241 tgtctcacca gttctctata caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga
    54301 agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa tcagtaattt
    54361 acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac ctggatataa
    54421 tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg cggctattgt
    54481 gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg gtgtaatgaa
    54541 agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa cattcatttt
    54601 atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc ttgttctacc
    54661 tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct tgttgatgtt
    54721 agtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa tcgatccgtt
    54781 gaaggcaatt ggataagaag gaggaagaac atgaaagcaa tagaatttaa agaagtagaa
    54841 aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac catgagtatc
    54901 gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag tacttttttg
    54961 actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa tgatcaagaa
    55021 ttcagtaatc aaaaagaaag cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt
    55081 ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt attagtagat
    55141 aagattaaac atgaacatcg tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg
    55201 gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca aagggtcgca
    55261 atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc aactgctagt
    55321 ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc aaaagacaaa
    55381 aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg cgatagaata
    55441 tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag gtggaaaaat
    55501 ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga ctgacttgtt
    55561 tatgtccaag ggatatctcg gcacttcaac aagagaaatc gcacaaaaag ttgggatcac
    55621 ccagcccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg cagttttaga
    55681 aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg
    55741 atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc tggtcgattt
    55801 gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag atcatctttt
    55861 ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag caaaccaatc
    55921 tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct tagtgttagc
    55981 accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat
    56041 cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag ggagaaaata
    56101 gttaggtgaa gaagcaagat atgacgaaga tcgttatatc ttgcttcttt atataggtag
    56161 tttttcataa agacaaattt gttattctct catgattatc agggtatatt tttatttatt
    56221 atgtcggtgt tccaggaagt gttttaattt aataacgaag aaattaattg tttgtagaat
    56281 gaaggaaact atttattggg tagatgaatc accacgaata gtcaaaagga gatttcagga
    56341 tatgccaaaa atgaaaaaaa tcattttagc agtaatgtta ttttctacgg ttatatcttt
    56401 tacagcccct tttttgctta cttaagctga ttttaagttt tggcccttag tctggatcta
    56461 cgaggtgaga gtcaagaatg aaaaaaataa ttggagcttt tgtatttgca atcattatca
    56521 ttattatctg ttttcaaata gatgtttttg gtcaaaaaaa gatagttgga caaacggtca
    56581 gcagtacgaa cagtacggtt acaaagacaa aggaatcatt tgatgataca gaacaagaga
    56641 cattaatcaa aatcggaaaa aatgaccgta cactatatac agatgactcg ctaactaccc
    56701 cacttgcaac tataaacggc ggagagctgg cggagtttct ttctgaaaca aaaaatgctt
    56761 atcagatcaa gacaaatgat ggctatactg gatatttagc cctcgaagat ggaaccaaag
    56821 tcacaaagaa tatacaaaca aaaccggaag agctatctga tgcagtgatt gtattagatc
    56881 ctgggcatgg cggaaatgat actggggcat taagcaatga tgaacaaaca gaagaaaaag
    56941 atataacatt aagtacagcc ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg
    57001 tttatttgac ccatactaca gatgaattag tacagcttgg agatatatgc gactacagtg
    57061 aagaaaaaaa ggcagatgtc tttatcagtt tacacgcaga ctctacggaa tatgcgaatg
    57121 aagcaactgg aatcacgaca tattattact atggacaaga ggaaacatta gcacagacaa
    57181 ttgctgactc cttcactgat ctgcctctgg attcaagagg aatctccact gggaactatc
    57241 aagttcttcg agaaaatctt caaccttcta ttttaatcga gatgggttat atgaataatg
    57301 atagtgattt aaaggaatta gtaacagaca gttatcagca gcagattgct gcaagtttga
    57361 cacaagcatt gaccacttat tttcagtaat aaataagccc agccaaacaa aaatagctcc
    57421 tcatattttt cgtttggccg ggcttattat cgcagatgca agcttttgaa caccgtttat
    57481 ttttttagta gcttcaaagc tttttctgta tttgcaaagt gaagtttggc atatttttca
    57541 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    57601 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    57661 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    57721 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    57781 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    57841 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    57901 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    57961 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    58021 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    58081 ggaccgaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    58141 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    58201 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    58261 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    58321 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    58381 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    58441 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    58501 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    58561 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    58621 aagcggtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    58681 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    58741 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    58801 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    58861 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    58921 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    58981 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    59041 ttatcaaaat aagaaaaatt taaaaaaagt tagaagagaa aggaacgtag catgctgagt
    59101 ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg cgggtttgct
    59161 ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca gcatttttac
    59221 aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac gccaacatca
    59281 aagttagcat tttttgatca ggtatttgcc tttcacctag atgaagcttt ttatgcagga
    59341 actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt gggggttttt
    59401 gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc aggaggcatc
    59461 ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact tgcctttgtt
    59521 ccattagatg tggtccaaaa tcaattcggc gagcatagtt tcgctcgctt tatcgttgag
    59581 agaacgccat ttcttaccaa caagatgtat gagctttggg taacgaatat tttgaattaa
    59641 ggaaaatagt gctggaaaat atttcgtttt ttgtacagag tagattattt aagaaggctg
    59701 cgtagcgtat gtccggcaca gctctttttt catagtgaaa gataaggtga taaaatgaat
    59761 aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac agatggtcag acaatttgta
    59821 gtgactgcac aaggaaaaga agaactggca gaattggtac cagtgagcga ggaacaaacg
    59881 atcacaaact ggcttcaaga aactgaggat ggattgaaag tgcaacgtct gcgaggcggg
    59941 atccctatac ctaaacttga aaatatccgt ccccatatga aacggattga gatcggagca
    60001 gacttgaatg gagtggagct tgcacaagtt tccagagtat tgtctacgac aagcgaattg
    60061 aatcgtttca ttgatgatct ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg
    60121 gcagatcagt tagtcacgat ccctgttttg agccgccgtt taaaggaagc aatcgatgaa
    60181 gacggacgcg tgactgatga cgcttctcct gagttaaaga gcataagaca gaacattcgg
    60241 cgaagtgaac aagctgttcg tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag
    60301 tatttaagtg atgcgatcat caccatgcga aatgaccgct acgttatccc agtcaaacaa
    60361 gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa gtgcttcagg acagacttta
    60421 tttattgaac caaaacaagt ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct
    60481 gaacgaaatg agattcaacg tattttaagt gaactttctg ctgaacttgt tccccatcgt
    60541 caagaaatca tccacaatgc ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca
    60601 cgatttggta aagaagtaaa agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc
    60661 ttgaaacaag caagacatcc actgatcgat caggaaaaag tagtttctaa tgacatcaca
    60721 atcggaaaag actatcaagc catcgtcatt acaggaccta acacaggtgg gaaaacgatc
    60781 acgttgaaga ctttaggtct gttacaactg atggggcaag caggattacc gattcctgca
    60841 ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg cggatatagg agacgaacag
    60901 tcgattgagc aaagtctatc gaccttttct tctcatatga cgaacactgt agatatttta
    60961 tcaaaagtca atgaaaaaag tctggtatta tttgacgagc tcggtgcagg aacagatccg
    61021 caagaaggtg ctgctctagc aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat
    61081 gtgatggcaa caacgcatta tcctgaattg aaagtttatg gatataatcg ggcaaatacg
    61141 attaatgcca gcatggagtt tgatgtggat acattaagtc caacgtatcg tttgctgatt
    61201 ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc gattaggtct tgatacagaa
    61261 gttattgatg aagcgaagca gttgatgaat gatgagagcc aagatttaaa cgaaatgatc
    61321 acagatttag agaatcgccg gaaaatggca gagaccgaat atctggaaat gcgtcatttt
    61381 gtttctgagg cacaagaact tcacgatgat ttgaaagaag cttacagcta tttctttgaa
    61441 gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg
    61501 gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa tgcaacagca gattgggcaa
    61561 ggaaatgtga aagagcatca gttgatcgat gcaaagaccc aattagcaaa tctacatcaa
    61621 gaagaaactt tgaagaaaaa taaagtattg aagaaggcga aagaacaaaa aacgttgaaa
    61681 ccgggagacg aagtgttggt tacgacttac ggccaaagag ggacgctttt acgtaaaaac
    61741 gggaatcagt ggcaagtaga aatcggtata ttaaaaatga atgtgtccga agacgagctg
    61801 acgcctgttg ctcctcaaaa agagccgaca caacgagtta tccatgctgt acgatctgaa
    61861 tctagtagtc acgtgccgaa tcaattggac cttcgaggaa aacgatacga agaagcgcta
    61921 agtgaggtag atcaatattt ggattctgcc attctagctg gttatcctca agtgactatt
    61981 gtccacggaa aaggaacagg cgcacttcgc aagggaatta ctgattatct taaaaaccat
    62041 cggagcgtca aaagctttga gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt
    62101 gttaaattta agtaaagctt actaaaggta agcagatggt tcgctatcca agtatagaaa
    62161 tgctatacta gtcatagatt ttaaaaatgg aggtctttga tatgtcacaa gtaattacag
    62221 ataagacatt taatgaagaa acagataaag gacttgtatt gattgatttt tgggcaactt
    62281 ggtgtggtcc atgtcgtatg caagcaccga ttttggatca gttggaacaa gaatatgatg
    62341 aagaagaatt cagaattgct aaaatggatg tggatgaaaa tccagaaact cctcaacaat
    62401 tcggtatcat gagcattcca acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag
    62461 ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat cgatcaatat ttataaaaac
    62521 ttacagcaaa aataagctga gggtgggact gaatccagtt ccgtcctcgg tttttttgcg
    62581 gttgagttaa ggttattcaa attaatattt tttgagtata attacgttgt caggctggat
    62641 tgtttttttg acagacatgc tataataact ttaattgaat atgaagggga gtaccagatg
    62701 aacgaacgaa tcaaaaacaa attagcttta cttcctgatc agcccggctg ttacttgatg
    62761 aaagataaaa atggaacgat catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc
    62821 cgctcatatt ttactggtag ccataatacg aaaacggaac ggcttgttag tgaaatcgaa
    62881 gactttgaat acatcgttac agaatcgaat atcgaagcat tgctcttaga gatcaatctg
    62941 ataaagaaaa atgatcctaa atacaacatt atgttaaagg atgataaaac ctatcctttc
    63001 cttaagataa cgaatgaaaa atatccccgt ttggtgatta ctcgtaaggt actaaaagac
    63061 aaagcactgt attttggacc atatcccgat gtcggtgcgg cgaatgagac aaagaagatc
    63121 ctcgatcgat tatttcctct gagaaaatgc aaacctagtc agacgaagga gccttgtctt
    63181 tactatcatt tgggacaatg tctgtgtcct tattatttcg acgtagatcc gaaagtctat
    63241 acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca
    63301 gagatccatc agaaaatgga aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa
    63361 taccgagagc agatccgtgc cattgagaca atcatgactc gccaaaaaat gacaaatact
    63421 gatttactgg atcgagatgt atttggttat gcgattgata aaggatggat gtgtgtccaa
    63481 gtgtttttcg taagacaagg aaagctaatt gaacgagatg tttcaatgtt tcctttctat
    63541 aacgaagcag aagaagattt cttgacttac ctcggtcagt tttatcagga aaatgagcat
    63601 ttcattccta aagaagtctt gattcctgat acgatcgaca agcccagtgt agaagctttg
    63661 ttagctacga aagtgctgca accaaaacga ggagaaaaga aaaaattagt tgaattggcg
    63721 agtaagaatg cctcagttgc tttgaatgaa cggtttgatc tgattgccag aaaacaggaa
    63781 cggacgatcg gagcagttga acgtttagga aacgcgatga atatcccgac cccaatacgt
    63841 atcgagtctt ttgataactc taatatcatg gggacgaatc ctgtggctgc gatggtcgta
    63901 ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat ataaaataaa aacagtcaac
    63961 ggaccggatg attatgcatc aatgagagaa gtcatctatc gcagatattc gcgagtgatt
    64021 cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg gaggaaaagg acaagtagat
    64081 gtggcaaaag atgtcttaga aaatcaatta ggaatcgata ttcctattgc tggcatggca
    64141 aaaaacgata aacataaaac aaatgagttg ctattcggta cagatttggc tgtagtaccg
    64201 cttgagcgaa attcaccaga gtttttctta ctccagcgaa tccaagatga agtccatcga
    64261 ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca gttttgcttc ccgattagat
    64321 gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg
    64381 aaaaatatca cagcagccac gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc
    64441 gcacaaaacg tatttgataa attacatcag gaatgaggaa agggcacttt acaaagaaag
    64501 taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa
    64561 taaatcgctt acgtctggtg tctaaggata tatgtgattt cttgaagaag gagtgaagaa
    64621 atgttagaag tcaaggatct tgttaaaact tttgggaact acacagctgt cgatcatgtc
    64681 tctttccaaa tccccgatgg aaaaatcatg gggctaattg gccaaaacgg ggctgggaag
    64741 acaacgactt ttcgtttgat cttggatttt ttgacacaag accaaggaga agtgttatgg
    64801 aatggccatc atcttgggga gaaagattat gatgtcatcg gttatcttcc ggaggaacgg
    64861 ggactttatc cgaaagtaac gattcaagac caactgcttt attttgcaga acttagaggg
    64921 aaatcaagaa aagagattga accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa
    64981 gggaaaaaga cggataaagt aaaatctttg tctaaaggaa atcagcaaaa agtccagctg
    65041 atcgccacgt taatccatga acctaaattg atcattttgg atgagccatt cagcgggtta
    65101 gatccggtaa atgctgaatt gctaaaagat ggaatattgg aattgaaaaa acatggttca
    65161 tgtgtcattt tttctagcca caatatggat aatgtagaaa aaatctgcga tcatttgatc
    65221 atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac atgagattcg tgaatcattt
    65281 ggccgtacga agttattctt ggaatctggt ttaagccaac aggaagtaga agaaatcgaa
    65341 ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag agattacctt agaagatcct
    65401 gaagctggga aagaaatctt tactcgtgcg actcagttcg gctacattcc tatgtttaac
    65461 cagcaaccgc caactttgga agagattttc aaattgaaag caggtgaaat cgatgcgtaa
    65521 gttttggatt attaccaaag atgtctattt aaaaaatgtt aagtcgattt ctttcttgat
    65581 catgatatta gtccctttta tcatgctggg tatcatttat gtagcaggaa actttgctca
    65641 acaaaatagt gatgtcaata aaatcggcgt attggctgat aatgagcaaa tcagtcagca
    65701 aatgagccaa gtcaaaacag atgattttga gttcaaagca gttgattctg aagaaaaagc
    65761 acaaaaagag ctttcggaag aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga
    65821 taagataaat gggatgcttt atagcgaaaa ttcattagga caaagtacac aactactgat
    65881 acaacaacaa ctgactggct tgcaatcgat gcttcgagcg agtcaattag gcatttcacc
    65941 agaagaagta gctagcttga gccaacaagc aagtttgact cgacaaaaag tcaattttga
    66001 ttcaaaagga aaaatgacag tcggagaaga taactcgaca gtccaatacg tcgtaagtta
    66061 tgtagcaacg attgtcttgt tcattattat tttgacgtat gcgcagatca ttgcacaaga
    66121 gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc ctgtccagta cgactgcaca
    66181 aaagcatttt tacggaaaat taacaggtgt tttacttgtt gcattaacgc aaatggcatt
    66241 atacggtatt atttttggta taggatacag tcaattcaaa gatatggaaa tggtcaaaaa
    66301 tatattagac ggtatctcat tggataactt gattggacca ttcttgtggt attctcttct
    66361 attcatgatc tttggcattt tgattttttc tgttttagca gctttatgtg gctctttggt
    66421 caacaaagca gaagatacag caaaagcaat tttgccagtg acttatctat ctctaggcgg
    66481 atacatgctt ggattgatac taggagcttc agatccaaac aatatcgtta ttcggatcac
    66541 ttcgtatatt ccattcttat cttcatatat tatgccggtt cgcttagcaa atgagacagt
    66601 cggtatgggt ggagcattga tttccttgtt ggtacttgta gccgtaacat tcttattgat
    66661 gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt tatagcgaag gcggattatg
    66721 gagttcattg aaacaatcga tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa
    66781 tcctaaaata cagaaggaag ctggacatct attgttccca gcttcttttt gtatagacct
    66841 attttattta ttttactata ttggatatat attcattgaa aatagtgtat aacaacttta
    66901 taatattgag tataccaatt tttggaggcg ttttaatgga ccgttattta gatttacttt
    66961 cagaaaaatt cccctcaacg gaggatgtca tcacggaaat catcaatctc gaagcaattt
    67021 tgcagcttcc aaaaggaaca gagttatttt tgagtgatat acatggcgaa tttcctgctt
    67081 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gacctttttt
    67141 ctgaacaaat gacggaaacg gatatcagcc aattcactat ttttacggct tatccagaat
    67201 atgcattaac gactgattgg tacaaagaac aagataaatc gcagctgatc catcatttga
    67261 tcgatctttt acggtttacg acagtcaaat atacccggtc aaaagttcga aaaggattgc
    67321 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgaccgt atcaatggaa
    67381 aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt gatgaaggaa gaagaaaaat
    67441 ttttaacgaa acttgcacag acgatccaaa aatctgtcat cgatcatttg catatcgttg
    67501 gagatatttt tgaccgagga actcaagcag ccaaagtgat ggatcgaatc atggattttt
    67561 cttctgtaga tatccaatgg ggaaatcatg atattttgtg gattggtgcg tattgcggct
    67621 ctgaggcatg tttactgaca cttttacgga ttgcagcacg ctataattat ttatttgaat
    67681 tagagaaaga atatgggttg aatttacgtc cattgttttc ttttgctcat caaacttatc
    67741 agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag
    67801 aattagaaaa aatccatcag gcactttcta tccttcaatt caaatcagaa catcagttat
    67861 tggatcgtcg acctgaattt aaaatggacg atcgtaaatt gctggaaaaa atcgactatg
    67921 aagcatcaac gattgattta gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa
    67981 cgatccagcc agatgatcca aaaaaattct tggaagagga acaaaaagtg attgatagtt
    68041 tgatgtattc attccagcac tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa
    68101 aagggggaat gtatctcacg aacaatcagc atgtgctgtt tcatggctgt atacctgtag
    68161 acgagaaggg acagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
    68221 tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga tctgactgca aaagaagatt
    68281 tagcaaccga tttgatttgg tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga
    68341 gtaaaatggc gacttttgaa cgttattttc tcacagagcc tcatacgcac gtcgagaaaa
    68401 gcaatcctta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttagcagaat
    68461 tcgacacaaa agaagaaggg tcagcaatca ttaatgggca cacgccagta aaagtaaaaa
    68521 aaggggagtc accgatcaaa gcaaatggaa aagtatttgt cattgacgga ggtttatcca
    68581 aagcttatca aaaaacgaca ggaattgccg gttattcact attatgcaat tcttatggtt
    68641 tccaaatcgt gacacattat ccgtttttgc ctattgaaca acaatttgca aaaaaatccg
    68701 accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc acgcaaactc aatcgtgata
    68761 caacaaaagg tatggaactg cagcagcaga ttacccagct caaaaggctg ttggactatc
    68821 gaaaggacga ttgagaagaa ttccagtgaa cattgttcca tagactggag actgagacaa
    68881 aagtcgtgtc gcagtctctt tttccggata aacggtgttc ttctgccaac tcctcggtca
    68941 caagtcacac tattcaacaa acatgaaaag ctgttttttg aaattgctcc ttgtgactca
    69001 gagttgaacg gcaggctcac gacctcttgg tataaacggt gttcaaaagc cagtttctcg
    69061 gtattaagcc aaatttatgc aaaaatgtga aaagccattt tcacaaaatt tttcttaata
    69121 ctcgaaacta aacagctttt tcacaacccc ctcagaaagt ctattaaaat tcattcacaa
    69181 agaaatcgaa taagcgctgt tcagatggat gtacacggtg ggtaagttcc ggatgccatt
    69241 gaacaccgag gattttatgc atatcatctt tgctttgaac cgcttcaatg agtccatcgt
    69301 tagaaaaagc gatggctttt aataaaggtg aaagatcttt gactgcctga tgatggtaag
    69361 aattcacaaa atatggatcg gggagaaggt tgcttaacaa actgtctgaa acaatcttga
    69421 cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc atgttttact gaccactttg
    69481 gatataatga aagatcttga taaagtgtac cttccaaaac gacattcaat agttggagtc
    69541 cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt
    69601 caaattggtc tcgttgaata tttgtttccg ttagctttgg atgaggatct tccatgtaaa
    69661 gttgtggact gacatcttga ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt
    69721 gaggagctga atctggagac atgactggca gaataagagg caatccttga gcatctaaaa
    69781 ctgcatccac gaatccttgc ggtgtatagc tcacttgatt tccttggaaa gtatctgttg
    69841 ctcgaatcag ttgatttccg gcaatgccga tgattggttt catttgtatt ccccctaaag
    69901 tagacttatt gtaacaagga tttaaaaaaa attaaactat gtaagacttg cccctatact
    69961 tatctgttct tgctgtgtta ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat
    70021 agttgaaaat attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc
    70081 gtaagcttca aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg
    70141 cctatactaa gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc
    70201 ttttttaaat cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc
    70261 agaagaagaa aatgaaaagc gtgctcaaac actgcggcag cagctgaaga tctatgcaac
    70321 agaaaaagag caggaattgg aaacgatcca aacaaactat cgacaacaac taaaacagtt
    70381 ggtggaagaa aaagaacaat ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa
    70441 agcagaagca gacaaggtgc aagcaacttt gaaagatcaa tatcaaaagc atcagagtca
    70501 agcgatcggt gcgatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa
    70561 aagtgaccct catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa
    70621 tccaaaacgt tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtggaga
    70681 agtattttcc agataccacg attattgata aagaagcaaa attaagcgct ttaggtaatc
    70741 ggttgaaaga catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa
    70801 agaaactcca tttgaaacgt caagaacttt ccttacaaga tttggaagcc aattattccg
    70861 aagaaaattt cataaataaa ttgaaagaag tccttgattt aaaagaaaag tgggaacaac
    70921 taactgaaga acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc
    70981 tggatattgc tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga
    71041 gtgcagcaaa ttttgaaagt ttcaaggaag aactgagtaa gcttgatgac gtttatatgg
    71101 aagaaataga ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag
    71161 ttgctgttat agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg
    71221 aacaaaatcc taaagaaaaa ctgcaagaga ccaagcagca attatccatt gttcacgagc
    71281 agcaaaagaa gataacgaca gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat
    71341 gggtagaaga agtcacactt gccgttgcag aacgagaaaa aataaaagaa cggtttatcc
    71401 atgcgactta tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc
    71461 tgcatgtgtt aaacgaaacc gtatcagaag aagatatata cgtcagtttc gaaacaccaa
    71521 actcagaaga gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac
    71581 cttttgaatt gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacac
    71641 cttggatgac accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttatg
    71701 gtttgctgat gctcattggg acaatactag ctcaaaaact acttgttcta ccacgcggga
    71761 tgaaacgttt cgtaaaattc tttgagattc tctcgatacc atcgatcatc tggggattga
    71821 tctacagttc atttttcgga cagtcattac caaaagaact gtttggcatc cgcttgcctt
    71881 tcccaatcct atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg
    71941 gtctgataca gattttggtt ggattatttg tggcagcaaa ggaaaatatc aggagaaaag
    72001 attacttgag tgctgtcagt gatggatttg cctggcaagg gatcctaatt gggatcgtta
    72061 ttgcgttggt tggtgccatg ttgataaaaa atacagcatt tgtttacctt ggcgctgggc
    72121 tatcgatcat tgctgcctta tgtatcttga tcgttccgat tatccaaacg ccgtctaaag
    72181 tcaaaggtgc tgccaaaggt gcgtataatc tttacggact gaccggctat atcggtgatt
    72241 tagtcagtta tacacgtttg atggcattgg gtatttcagg cggaagtatt ggagcggcat
    72301 tcaatatgct agttgctttc atgccgccag ctgctcgatt cagtgtaggg atccttttga
    72361 tcatcgcttt acacgcactg aatatgtttt tgacactgct aagtgcctat gtccatggcg
    72421 cacgattgca gtatgtcgaa ttttttggga agttttatac aggaggcgga cgtgcctttg
    72481 atccgctgaa aacggcggaa aaatacgtca acatcaatca caagaaaaaa aacaataaat
    72541 aattggagga tttttatata atgatggatt acttaattag tcaaaatggt ggaatggtat
    72601 ttgcggtatt agcgatggca acagcgacga ttttttcagg gatcggttca gctaaaggtg
    72661 ttggaatgac aggtgaggca gcagcagcat tgacaacaag tcaacccgaa aaattcgggc
    72721 aggctctgat tctgcaattg cttccaggta cgcaaggttt gtatggattc gttattgcct
    72781 ttttgatttt tatcaactta ggaaatgaca tgtcagttgt acaaggactg aactttctag
    72841 gtgcttctct gccgattgct tttacaggct tgttttcagg tattgcccaa ggaaaagtcg
    72901 cagcggcagg tattcaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt
    72961 ttgctgcgat ggttgaaaca tacgcgattt taggtttcgt tatttccttc ctattagtgt
    73021 tgaatgccta agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca
    73081 gatgaacgaa gcagcagagc aggaaagagc ggcgttagaa caagaagagc gaatgaagat
    73141 cgatcaaaac tttgaacaaa aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga
    73201 aaaacaaatc gaattactcg aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga
    73261 agtacgacaa gaaaatttga atgcgaagca ggaattttta agacgattgt ttgcagatgc
    73321 ggtaactgaa atggaaaatt gggatgaatc tgaacaaatc cagtttatca aaaatgcatt
    73381 gtattcatta cctttgacag gaaaagtagc attcattgct ggagaaaaat cagcagccta
    73441 tctttctcag acgttgttgg atgaatggaa caatgaactt ccctttatga tggttttaag
    73501 tgatgaaact gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa
    73561 ttttcttttc agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa
    73621 tcaattattc gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt
    73681 cgcggaagag agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat
    73741 tctgtcgaag cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac
    73801 ggatatgaat atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg
    73861 ttaaaggaat cagcaccgga gcctgaaatc gtttggatct atacgatgcg ttatactttc
    73921 cataatctga aggttttgac aaaagctgag atgacaaatc aaaatctgga ccatttgtat
    73981 atcgacgatg gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca
    74041 aatgaacttc ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag
    74101 tctaccattc ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga
    74161 cggcttgccg ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac
    74221 ttgaccaata tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg
    74281 acgacggtac tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat
    74341 aaagatatgg aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc
    74401 cctgtcatcc gtgagggaaa tattgatctc gtaaagcttg aacagttgaa agatgattat
    74461 ctaagttcat tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc
    74521 tttttgaacg caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga
    74581 agccatttcg aatcagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat
    74641 cggtgtagtt ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg
    74701 ttatggtaca accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta
    74761 tggcgtgatt tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta
    74821 caaggaacaa atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat
    74881 agggctggaa gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta
    74941 tgaaaaggag atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt
    75001 aatggctgag aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg
    75061 agttatcgga gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga
    75121 gacttctgga attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga
    75181 attaggacca gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt
    75241 tatggaaatc acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca
    75301 tgagaaaaaa tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga
    75361 tgttatcggg atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg
    75421 gataaaagga acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg
    75481 tgtcattgaa accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag
    75541 acgtagtcgg ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg
    75601 agtgattgat acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt
    75661 tggtgcaggg aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt
    75721 tgtctatgtg ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc
    75781 tgaattgatt gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa
    75841 tacatcaaac atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc
    75901 ggaatatttc cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg
    75961 ggcagaagca cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta
    76021 tccagcttat cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc
    76081 attaggatca gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg
    76141 aggggatatt tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg
    76201 tcttgattcc agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta
    76261 ttctctttat tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc
    76321 atccatggtc accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt
    76381 gcgtttggta gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa
    76441 atccattcgt gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc
    76501 aagagagaaa caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg
    76561 tgcgttgtcg ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga
    76621 aaggatcgga cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat
    76681 tggtgaaatc aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta
    76741 aagaatatcg tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg
    76801 gtgtcaaata tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac
    76861 aagtattgga agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta
    76921 tcaatttacg tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg
    76981 aagacatgat cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga
    77041 tcctgcctga aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt
    77101 atccagatga gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc
    77161 gtgggcaaaa attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc
    77221 agatcgcgcg acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg
    77281 ctattggaat cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg
    77341 caatcgaccg ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg
    77401 ctactcctcg tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg
    77461 ttttggttat catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag
    77521 cacggcgaga agttccagga agaagaggat atcctgggta tctttacacg aacttagcta
    77581 ctttattcga acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga
    77641 ttctaacaat gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta
    77701 cagaaggaca gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg
    77761 atgtactccc gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag
    77821 aagaccatgc agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa
    77881 aagaattagc cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga
    77941 agtttgctga gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga
    78001 ttactgaaac acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa
    78061 aacgaatcaa agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg
    78121 cacgattgaa tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa
    78181 ctgccacaag agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca
    78241 tcctgttgat tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag
    78301 caatgtctga ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat
    78361 ttgttttgcc ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa
    78421 aagtacctgt gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg
    78481 ggtatttgaa ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc
    78541 caaaactttt ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg
    78601 aaaagacacg tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa
    78661 cgatctatta tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga
    78721 tcaaagtaaa aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac
    78781 gatgattaaa caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt
    78841 aggatttttt ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa
    78901 tagtgggcat gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt
    78961 aacgggattg acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat
    79021 catgcttttg attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc
    79081 attgataaag aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct
    79141 agaagaagta tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgtgat
    79201 ccaattgatt ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa
    79261 aggtatctgg tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt
    79321 gttaggagac agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc
    79381 tttgatcatt tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca
    79441 gaaaaagaag atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt
    79501 aggcggattc gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa
    79561 tatgtttcaa cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata
    79621 ttattcagtt gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat
    79681 gtacatcggc ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt
    79741 gttgctgatc cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg
    79801 taccatccga caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt
    79861 gtgtgtagtc gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat
    79921 cgaatatatt gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt
    79981 gacgccagac ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg
    80041 agttggtgta ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa
    80101 atacaaatat ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta
    80161 gtgatttagt aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc
    80221 aaaatgttcg tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt
    80281 tttattgaaa ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata
    80341 tttttttatt ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga
    80401 ggatagggaa attcgaacga atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg
    80461 ataaagtcgg ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg
    80521 atcaactgga agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag
    80581 agaatcaaaa agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt
    80641 tgcttcattt gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac
    80701 atttatatta aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata
    80761 agcaactcgc aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt
    80821 aggtaataaa ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga
    80881 atggatatca tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc
    80941 tcgtcttttg tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac
    81001 accatgaatc ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc
    81061 gtcaaaatca attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc
    81121 gtatgtatat cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat
    81181 agccaatcca ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc
    81241 ttgagttttt aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg
    81301 gtaattaagc aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac
    81361 gaatttatta cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac
    81421 ttcattggta gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc
    81481 aatattcgta tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt
    81541 aaaatttaaa tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg
    81601 taatttattc tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg
    81661 cttcaatttt tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg
    81721 cattttctcc actccttaaa attgtatacc atacaatttt accattgatt gtattgattt
    81781 tagaagttaa tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt
    81841 agtagcttct tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta
    81901 tgaaagtggt aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg
    81961 caaaaatatg tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa
    82021 agtcattacc gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat
    82081 tttcttgttt gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac
    82141 ctggattcga acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc
    82201 agaaacactt gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc
    82261 taccattcgt cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac
    82321 ttttatcgct aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt
    82381 agaagatgca gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt
    82441 tcttcaaaaa gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc
    82501 tgatacaaga gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta
    82561 ctcagctgcc ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga
    82621 ggaatcttgt attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa
    82681 aggagaatcg aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg
    82741 tgcagaatat atttataaca aattagagaa aggggcttta aaatgaactt agattattac
    82801 gtagttgatg catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta
    82861 gaagaatggc tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa
    82921 acagcattta cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga
    82981 gaaatcgatc tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac
    83041 aaaatacctg atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga
    83101 attaaagatt attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg
    83161 tctgaatatg aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta
    83221 tttttcgtat tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc
    83281 aaaaattttg aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt
    83341 gtttctagaa ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca
    83401 cattctaatc ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat
    83461 caaatgtcat caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata
    83521 ggaggaaaag cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa
    83581 ttaaaaataa attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac
    83641 gcaaactttt tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt
    83701 ttattcaatc aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata
    83761 accatcaggg tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc
    83821 agtaatctca agaccagcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc
    83881 tatagcgata tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt
    83941 caactctaat tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc
    84001 tggaaaatca cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga
    84061 tgcttcaaga tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct
    84121 tttcctttta ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca
    84181 tgagaaattt ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat
    84241 ggataaacca atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc
    84301 atatattgtc atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt
    84361 ttttcttcct ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga
    84421 gctgatagaa gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga
    84481 gtatttttac tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc
    84541 tgattcttgg aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag
    84601 ccctcaagaa gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg
    84661 gatcgaaaaa aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta
    84721 tttattacag tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag
    84781 tgatgacatt tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac
    84841 cagcatattc aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt
    84901 gatcaatacc aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat
    84961 ttagtacttc gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt
    85021 gcggtaaacg cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga
    85081 cgatgttcat gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta
    85141 aacttgcttc gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt
    85201 catcgatcga atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat
    85261 cttcatgtgt cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg
    85321 ccccgttata agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt
    85381 cctggacacc tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag
    85441 cagcggcaat cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac
    85501 catcgatgtc gatagcgact agtttgatag acataatttc ctccaatata ttttaattta
    85561 tttcaatcaa tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata
    85621 aatcataatg atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat
    85681 ctccttgttc ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca
    85741 aagttccgtc atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat
    85801 aaaaatcata aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc
    85861 cgaccttttc tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa
    85921 aagtagcaga tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag
    85981 gatcagcaga ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga
    86041 ggtattcttc taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt
    86101 caaaactgct ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa
    86161 ttacttccat accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc
    86221 taacgatata atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat
    86281 aaggacgaat cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga
    86341 aataagcatc ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt
    86401 ggacaacttg tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac
    86461 cttcttctac tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta
    86521 cagtgatggc ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat
    86581 gaccgacatc atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc
    86641 ctccgttgcc tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg
    86701 aaatctcata aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga
    86761 aagaagaagt gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca
    86821 aatctaagat tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt
    86881 tttccatagg cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta
    86941 ttacgttgtt ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt
    87001 agccagtcgg tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca
    87061 aatgcttctt tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc
    87121 attgtagcag gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat
    87181 tgataaaatc gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac
    87241 atcataacag aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca
    87301 tggatgctta aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc
    87361 ggtgcctttg gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg
    87421 gttatttttt ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct
    87481 gatacgatcc ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt
    87541 gtttggatcc cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg
    87601 cagtcatatt gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat
    87661 atatctgtta atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga
    87721 atcgcagggt tcattcaacc ggctcctttg tataaattca tattttctac aatattatac
    87781 tctaaaatca aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg
    87841 acaaaacaaa agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg
    87901 aattatcaca aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg
    87961 aagtgcaaga tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt
    88021 acatacgtta taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat
    88081 tagttccaga tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat
    88141 ttggctataa agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg
    88201 ctacttttac gaaagaactg catgttagtt tgaaagaccg tcccacagca gggaaggttc
    88261 gaatcgatta tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg
    88321 attttacagc gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa
    88381 ggagtagact gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca
    88441 aaagcgaatt atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca
    88501 tggatttttc tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa
    88561 ttcgtgattc actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat
    88621 taggggataa tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag
    88681 taaaccatgg aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag
    88741 tcaacgcctt tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag
    88801 atacagatct gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg
    88861 aagaaatcgc tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg
    88921 atgaagaaga cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg
    88981 atgatgaaga ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt
    89041 cttacgagag gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt
    89101 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
    89161 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
    89221 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
    89281 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
    89341 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
    89401 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
    89461 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
    89521 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
    89581 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
    89641 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
    89701 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
    89761 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
    89821 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
    89881 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
    89941 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
    90001 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
    90061 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
    90121 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
    90181 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
    90241 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
    90301 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
    90361 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
    90421 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
    90481 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
    90541 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
    90601 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
    90661 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
    90721 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
    90781 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
    90841 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
    90901 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
    90961 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
    91021 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
    91081 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
    91141 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
    91201 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
    91261 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
    91321 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
    91381 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
    91441 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
    91501 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
    91561 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
    91621 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
    91681 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
    91741 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
    91801 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
    91861 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
    91921 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
    91981 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
    92041 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
    92101 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
    92161 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
    92221 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
    92281 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
    92341 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
    92401 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
    92461 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
    92521 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
    92581 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
    92641 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
    92701 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
    92761 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
    92821 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
    92881 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
    92941 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
    93001 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
    93061 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
    93121 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
    93181 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
    93241 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
    93301 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
    93361 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
    93421 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
    93481 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
    93541 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
    93601 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
    93661 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
    93721 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
    93781 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
    93841 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
    93901 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
    93961 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
    94021 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
    94081 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
    94141 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
    94201 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
    94261 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
    94321 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
    94381 atggcaatcg cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca
    94441 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
    94501 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
    94561 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
    94621 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
    94681 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
    94741 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
    94801 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
    94861 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
    94921 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
    94981 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
    95041 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
    95101 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
    95161 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
    95221 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
    95281 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
    95341 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
    95401 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
    95461 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
    95521 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
    95581 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
    95641 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
    95701 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
    95761 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
    95821 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
    95881 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
    95941 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
    96001 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
    96061 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
    96121 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
    96181 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
    96241 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
    96301 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
    96361 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
    96421 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
    96481 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
    96541 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
    96601 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
    96661 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
    96721 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
    96781 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
    96841 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg
    96901 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
    96961 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
    97021 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
    97081 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
    97141 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
    97201 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
    97261 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
    97321 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
    97381 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg
    97441 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
    97501 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
    97561 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
    97621 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
    97681 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
    97741 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
    97801 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
    97861 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
    97921 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
    97981 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
    98041 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
    98101 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
    98161 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
    98221 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
    98281 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
    98341 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
    98401 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
    98461 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
    98521 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
    98581 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
    98641 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
    98701 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
    98761 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
    98821 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
    98881 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
    98941 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
    99001 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
    99061 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    99121 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    99181 ttagttaagt aatcgaactc tctacttgct gaaatatcag caggtagaga gtttttttgc
    99241 aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca tccttgaaaa
    99301 aggaaagcta acaataacta gcatcatata agagctttta aggatagaac agtagaatag
    99361 gaatctatga gcaagtcctc tcgtataaat aaaataggag ggaagtagca gcatattttt
    99421 cataaagtgg ctctctttct tcatttttac tttggttgct cctatttgaa aattcgagca
    99481 cactcaaata caataaaaag aaatggcaag ggagaggatt agatgaaaaa agaagaaaaa
    99541 atcgcgattt tacaagagat catccgaatt aaatcagtga atggaaacga aggtgaagta
    99601 gcagcctatt tgaataagct tttggcaaag catgacataa caggagagat tgtttcttac
    99661 agagatggta gagataattt gattgctcgt taccaaaagg gccaatcagg aaaagtgtta
    99721 ggcctatctg ggcatatgga tgtcgtggcg gctggtgatg aatcgtcttg gacctatgca
    99781 ccctttgcag cagaaatcca tgggaaccgt ttgtacggac gtggtgctac agatatgaag
    99841 agtggcttgg cagcaatggt gattgccatg atcgaactga aagagtcagg aaaaccattt
    99901 aacggaacag tcaaattatt agccactgtc ggagaagaag tgggtgaact aggtggggaa
    99961 cagctcacga aagcaggcta tgtagatgac ttagatgcct tgatcatcgg agagccaacc
   100021 aattacagtt tgatgtatac gcacatggga tcaatcaact atacagtcac ctcgcacgga
   100081 aaagaagcgc atagctctat gccagaccaa ggttataatg caatcaatca cctaaatgaa
   100141 ttcattacga aagcaaatgc tgaaatgaat cacctcgctg aaacaatcga gaatcctgtc
   100201 ctaggaaaaa caatccataa tgttacattg atcagtggcg ggaatcaagt caacagcatc
   100261 ccaagccatg cgcagctcca agggaacatt cgatcgattc cagaataccc aaatgataaa
   100321 atcattgcat tgctgcaatc aatcgtcaat gaattgaatc aagagacaga ctatcatttg
   100381 gaattgatga tcgattacaa caaaatacct gtcaaagctg atccagattc tcctttgatt
   100441 cattgcattc agcaacaatt cagccagcca ttacctttag ttggagcggc agcaacaacg
   100501 gatgcagccg aatttacgaa agctaaccat tccttcgact ttgtcgtctt tgggcctggt
   100561 gtcgttactt tgcctcatca agtagatgag tatgttgaaa tcgataatta tttggatatg
   100621 atcgaaaaat atcaaggaat tattttatcc tacttagcgt aagatttttt taataaatga
   100681 aaaaacagag ccagattagc attattt
//
LOCUS       DASHXG010000004        96484 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.004, whole genome shotgun sequence.
ACCESSION   DASHXG010000004 DASHXG010000000
VERSION     DASHXG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 96484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.004"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            153..1211
                     /locus_tag="U2R59_000323"
     CDS             153..1211
                     /locus_tag="U2R59_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HEM8964749.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1215..2249
                     /locus_tag="U2R59_000324"
     CDS             1215..2249
                     /locus_tag="U2R59_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HEM8964750.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYYIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2351..3067)
                     /locus_tag="U2R59_000325"
     CDS             complement(2351..3067)
                     /locus_tag="U2R59_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8964751.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3036..3821)
                     /locus_tag="U2R59_000326"
     CDS             complement(3036..3821)
                     /locus_tag="U2R59_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HEM8964752.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3812..4561)
                     /locus_tag="U2R59_000327"
     CDS             complement(3812..4561)
                     /locus_tag="U2R59_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEM8964753.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4859..5383
                     /locus_tag="U2R59_000328"
     CDS             4859..5383
                     /locus_tag="U2R59_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HEM8964754.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5399..6898
                     /locus_tag="U2R59_000329"
     CDS             5399..6898
                     /locus_tag="U2R59_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HEM8964755.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6986..7588)
                     /locus_tag="U2R59_000330"
     CDS             complement(6986..7588)
                     /locus_tag="U2R59_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8964756.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7692..8648
                     /locus_tag="U2R59_000331"
     CDS             7692..8648
                     /locus_tag="U2R59_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEM8964757.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8953..9909)
                     /locus_tag="U2R59_000332"
     CDS             complement(8953..9909)
                     /locus_tag="U2R59_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8964758.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10083..10643
                     /locus_tag="U2R59_000333"
     CDS             10083..10643
                     /locus_tag="U2R59_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964759.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10636..11460
                     /locus_tag="U2R59_000334"
     CDS             10636..11460
                     /locus_tag="U2R59_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEM8964760.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11470..12087
                     /locus_tag="U2R59_000335"
     CDS             11470..12087
                     /locus_tag="U2R59_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEM8964761.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12105..12788
                     /locus_tag="U2R59_000336"
     CDS             12105..12788
                     /locus_tag="U2R59_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEM8964762.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13471..14754
                     /locus_tag="U2R59_000337"
     CDS             13471..14754
                     /locus_tag="U2R59_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8964763.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14770..15657
                     /locus_tag="U2R59_000338"
     CDS             14770..15657
                     /locus_tag="U2R59_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8964764.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15674..16510
                     /locus_tag="U2R59_000339"
     CDS             15674..16510
                     /locus_tag="U2R59_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8964765.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16513..17136
                     /locus_tag="U2R59_000340"
     CDS             16513..17136
                     /locus_tag="U2R59_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964766.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17133..18425
                     /locus_tag="U2R59_000341"
     CDS             17133..18425
                     /locus_tag="U2R59_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8964767.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18784..18881
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18997..19578
                     /locus_tag="U2R59_000342"
     CDS             18997..19578
                     /locus_tag="U2R59_000342"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEM8964768.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19581..20888
                     /locus_tag="U2R59_000343"
     CDS             19581..20888
                     /locus_tag="U2R59_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEM8964769.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21304..21792
                     /gene="purE"
                     /locus_tag="U2R59_000344"
     CDS             21304..21792
                     /gene="purE"
                     /locus_tag="U2R59_000344"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEM8964770.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21785..22909
                     /gene="purK"
                     /locus_tag="U2R59_000345"
     CDS             21785..22909
                     /gene="purK"
                     /locus_tag="U2R59_000345"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEM8964771.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22922..24217
                     /gene="purB"
                     /locus_tag="U2R59_000346"
     CDS             22922..24217
                     /gene="purB"
                     /locus_tag="U2R59_000346"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEM8964772.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24339..25727)
                     /gene="ltrA"
                     /locus_tag="U2R59_000347"
     CDS             complement(24339..25727)
                     /gene="ltrA"
                     /locus_tag="U2R59_000347"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8964773.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26296..26673)
                     /locus_tag="U2R59_000348"
     CDS             complement(26296..26673)
                     /locus_tag="U2R59_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964774.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26929..27657
                     /locus_tag="U2R59_000349"
     CDS             26929..27657
                     /locus_tag="U2R59_000349"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEM8964775.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27657..27911
                     /gene="purS"
                     /locus_tag="U2R59_000350"
     CDS             27657..27911
                     /gene="purS"
                     /locus_tag="U2R59_000350"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HEM8964776.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27913..28584
                     /gene="purQ"
                     /locus_tag="U2R59_000351"
     CDS             27913..28584
                     /gene="purQ"
                     /locus_tag="U2R59_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HEM8964777.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28585..30807
                     /gene="purL"
                     /locus_tag="U2R59_000352"
     CDS             28585..30807
                     /gene="purL"
                     /locus_tag="U2R59_000352"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HEM8964778.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30792..32231
                     /locus_tag="U2R59_000353"
     CDS             30792..32231
                     /locus_tag="U2R59_000353"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEM8964779.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32254..33306
                     /locus_tag="U2R59_000354"
     CDS             32254..33306
                     /locus_tag="U2R59_000354"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEM8964780.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33303..33881
                     /gene="purN"
                     /locus_tag="U2R59_000355"
     CDS             33303..33881
                     /gene="purN"
                     /locus_tag="U2R59_000355"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEM8964781.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33878..35413
                     /gene="purH"
                     /locus_tag="U2R59_000356"
     CDS             33878..35413
                     /gene="purH"
                     /locus_tag="U2R59_000356"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEM8964782.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35429..36703
                     /gene="purD"
                     /locus_tag="U2R59_000357"
     CDS             35429..36703
                     /gene="purD"
                     /locus_tag="U2R59_000357"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEM8964783.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36825..37739
                     /locus_tag="U2R59_000358"
     CDS             36825..37739
                     /locus_tag="U2R59_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8964784.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37872..39437)
                     /locus_tag="U2R59_000359"
     CDS             complement(37872..39437)
                     /locus_tag="U2R59_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8964785.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39430..40881)
                     /locus_tag="U2R59_000360"
     CDS             complement(39430..40881)
                     /locus_tag="U2R59_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8964786.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40895..41911)
                     /locus_tag="U2R59_000361"
     CDS             complement(40895..41911)
                     /locus_tag="U2R59_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8964787.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42131..43219
                     /locus_tag="U2R59_000362"
     CDS             42131..43219
                     /locus_tag="U2R59_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HEM8964788.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43273..44799
                     /locus_tag="U2R59_000363"
     CDS             43273..44799
                     /locus_tag="U2R59_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HEM8964789.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44801..46006
                     /locus_tag="U2R59_000364"
     CDS             44801..46006
                     /locus_tag="U2R59_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8964790.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46263..47240
                     /gene="guaC"
                     /locus_tag="U2R59_000365"
     CDS             46263..47240
                     /gene="guaC"
                     /locus_tag="U2R59_000365"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEM8964791.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47504..48928
                     /locus_tag="U2R59_000366"
     CDS             47504..48928
                     /locus_tag="U2R59_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEM8964792.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            49389..50498
                     /gene="pdhA"
                     /locus_tag="U2R59_000367"
     CDS             49389..50498
                     /gene="pdhA"
                     /locus_tag="U2R59_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HEM8964793.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50501..51478
                     /locus_tag="U2R59_000368"
     CDS             50501..51478
                     /locus_tag="U2R59_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEM8964794.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51503..53146
                     /locus_tag="U2R59_000369"
     CDS             51503..53146
                     /locus_tag="U2R59_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HEM8964795.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53154..54560
                     /gene="lpdA"
                     /locus_tag="U2R59_000370"
     CDS             53154..54560
                     /gene="lpdA"
                     /locus_tag="U2R59_000370"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEM8964796.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            54722..54997
                     /locus_tag="U2R59_000371"
     CDS             54722..54997
                     /locus_tag="U2R59_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEM8964797.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            55003..55770
                     /locus_tag="U2R59_000372"
     CDS             55003..55770
                     /locus_tag="U2R59_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEM8964798.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            55938..57767
                     /gene="typA"
                     /locus_tag="U2R59_000373"
     CDS             55938..57767
                     /gene="typA"
                     /locus_tag="U2R59_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEM8964799.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            58028..59800
                     /gene="recQ"
                     /locus_tag="U2R59_000374"
     CDS             58028..59800
                     /gene="recQ"
                     /locus_tag="U2R59_000374"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HEM8964800.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            59914..60216
                     /locus_tag="U2R59_000375"
     CDS             59914..60216
                     /locus_tag="U2R59_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HEM8964801.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            60219..61382
                     /locus_tag="U2R59_000376"
     CDS             60219..61382
                     /locus_tag="U2R59_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8964802.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            61408..64836
                     /locus_tag="U2R59_000377"
     CDS             61408..64836
                     /locus_tag="U2R59_000377"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HEM8964803.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            64857..65981
                     /locus_tag="U2R59_000378"
     CDS             64857..65981
                     /locus_tag="U2R59_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964804.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            65971..66408
                     /locus_tag="U2R59_000379"
     CDS             65971..66408
                     /locus_tag="U2R59_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8964805.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            66392..66730
                     /locus_tag="U2R59_000380"
     CDS             66392..66730
                     /locus_tag="U2R59_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEM8964806.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            66849..67409
                     /gene="rsmD"
                     /locus_tag="U2R59_000381"
     CDS             66849..67409
                     /gene="rsmD"
                     /locus_tag="U2R59_000381"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEM8964807.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            67406..67897
                     /gene="coaD"
                     /locus_tag="U2R59_000382"
     CDS             67406..67897
                     /gene="coaD"
                     /locus_tag="U2R59_000382"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEM8964808.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            67887..68930
                     /locus_tag="U2R59_000383"
     CDS             67887..68930
                     /locus_tag="U2R59_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEM8964809.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            69089..69817
                     /locus_tag="U2R59_000384"
     CDS             69089..69817
                     /locus_tag="U2R59_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEM8964810.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            69933..70178
                     /locus_tag="U2R59_000385"
     CDS             69933..70178
                     /locus_tag="U2R59_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8964811.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            70175..70393
                     /locus_tag="U2R59_000386"
     CDS             70175..70393
                     /locus_tag="U2R59_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEM8964812.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            70529..71068
                     /locus_tag="U2R59_000387"
     CDS             70529..71068
                     /locus_tag="U2R59_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HEM8964813.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            71061..73334
                     /locus_tag="U2R59_000388"
     CDS             71061..73334
                     /locus_tag="U2R59_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEM8964814.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            73372..74418
                     /gene="holA"
                     /locus_tag="U2R59_000389"
     CDS             73372..74418
                     /gene="holA"
                     /locus_tag="U2R59_000389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEM8964815.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(74507..74761)
                     /locus_tag="U2R59_000390"
     CDS             complement(74507..74761)
                     /locus_tag="U2R59_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEM8964816.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(75161..75430)
                     /locus_tag="U2R59_000391"
     CDS             complement(75161..75430)
                     /locus_tag="U2R59_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964817.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(75900..76355)
                     /locus_tag="U2R59_000392"
     CDS             complement(75900..76355)
                     /locus_tag="U2R59_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HEM8964818.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(76493..78421)
                     /locus_tag="U2R59_000393"
     CDS             complement(76493..78421)
                     /locus_tag="U2R59_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEM8964819.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(78618..79451)
                     /locus_tag="U2R59_000394"
     CDS             complement(78618..79451)
                     /locus_tag="U2R59_000394"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEM8964820.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(79643..80347)
                     /locus_tag="U2R59_000395"
     CDS             complement(79643..80347)
                     /locus_tag="U2R59_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8964821.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(80370..80996)
                     /locus_tag="U2R59_000396"
     CDS             complement(80370..80996)
                     /locus_tag="U2R59_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8964822.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            81322..83697
                     /locus_tag="U2R59_000397"
     CDS             81322..83697
                     /locus_tag="U2R59_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HEM8964823.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(83721..84212)
                     /locus_tag="U2R59_000398"
     CDS             complement(83721..84212)
                     /locus_tag="U2R59_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HEM8964824.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            84399..85319
                     /locus_tag="U2R59_000399"
     CDS             84399..85319
                     /locus_tag="U2R59_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8964825.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYGMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            85473..85817
                     /locus_tag="U2R59_000400"
     CDS             85473..85817
                     /locus_tag="U2R59_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEM8964826.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(86007..86507)
                     /locus_tag="U2R59_000401"
     CDS             complement(86007..86507)
                     /locus_tag="U2R59_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8964827.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            87035..87118
                     /locus_tag="U2R59_000402"
     tRNA            87035..87118
                     /locus_tag="U2R59_000402"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:87069..87071,aa:Leu,seq:cag)
     gene            complement(87442..88080)
                     /locus_tag="U2R59_000403"
     CDS             complement(87442..88080)
                     /locus_tag="U2R59_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8964828.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            88415..88849
                     /locus_tag="U2R59_000404"
     CDS             88415..88849
                     /locus_tag="U2R59_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8964829.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            88872..89192
                     /locus_tag="U2R59_000405"
     CDS             88872..89192
                     /locus_tag="U2R59_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964830.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            89333..89524
                     /locus_tag="U2R59_000406"
     CDS             89333..89524
                     /locus_tag="U2R59_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964831.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(89595..89852)
                     /locus_tag="U2R59_000407"
     CDS             complement(89595..89852)
                     /locus_tag="U2R59_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HEM8964832.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            90010..90273
                     /locus_tag="U2R59_000408"
     CDS             90010..90273
                     /locus_tag="U2R59_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964833.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            90297..90485
                     /locus_tag="U2R59_000409"
     CDS             90297..90485
                     /locus_tag="U2R59_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964834.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(90568..90753)
                     /locus_tag="U2R59_000410"
     CDS             complement(90568..90753)
                     /locus_tag="U2R59_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964835.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            90968..91339
                     /locus_tag="U2R59_000411"
     CDS             90968..91339
                     /locus_tag="U2R59_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8964836.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(91489..91561)
                     /locus_tag="U2R59_000412"
     tRNA            complement(91489..91561)
                     /locus_tag="U2R59_000412"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91526..91528),aa:Gln,seq:ctg)
     gene            complement(91607..92035)
                     /locus_tag="U2R59_000413"
     CDS             complement(91607..92035)
                     /locus_tag="U2R59_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964837.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(92095..92853)
                     /locus_tag="U2R59_000414"
     CDS             complement(92095..92853)
                     /locus_tag="U2R59_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEM8964838.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            93148..93345
                     /locus_tag="U2R59_000415"
     CDS             93148..93345
                     /locus_tag="U2R59_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964839.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            93451..93933
                     /locus_tag="U2R59_000416"
     CDS             93451..93933
                     /locus_tag="U2R59_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964840.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(93991..94587)
                     /locus_tag="U2R59_000417"
     CDS             complement(93991..94587)
                     /locus_tag="U2R59_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEM8964841.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            94974..96440
                     /locus_tag="U2R59_000418"
     CDS             94974..96440
                     /locus_tag="U2R59_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HEM8964842.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        31118 a        16707 c        20493 g        28166 t
ORIGIN      
        1 aaaaatcact ttacataagt ttcaaaagtt tctttaattt cctattgttc aataagtaac
       61 aatgtaaaga taaaattaaa aatgttaata cgtattagca aaataaaagc tttttttatt
      121 gtgaataaat gaacataatt aggaggagaa agatgaactt atttgacatt tttcgatcga
      181 ctttgacaga tatgtcgatt gtcagtgcaa tcacttcaac agtttttatt atattattag
      241 ggtttgtttg tagaaaaaag gggatttttt ctgaatctgt tggaaaaatt ctatcgaaag
      301 tcgtcttaac agtggctttg ccagcactgg catttcgagc tttcatgcaa gatatcaata
      361 cagaattact gatgcaagga atcaatgtct tgatttgggg attagttatt tatattattc
      421 ttattctagt ttcaaaacct tttttcttaa gctataaagg ggataagcaa acaacgttgc
      481 gtgtcctgac gatctttggt tctacgacct ttttcggaac gcctatcgtc agtgcgattt
      541 atggtcctgt cggcgtgatg tattcctcaa ttttcaatat tggctaccga atctttttgt
      601 attcttatgg atacataaaa atgagtggct tgaagatgga agctaaaaat atcaaagcga
      661 tgttcgtcaa tccaatcatt atcgctactt ttgccggcct tttcatttgg ctgttccaag
      721 ggtatctgcc acaagtgtca gttacaggtg cagaaggaga gataagccaa gtagcgtttt
      781 tgcgaattga ccagactgca ccgtggctat ttcagccgat ggattattta gctggtttaa
      841 gttcaccatt ggcgtggcta gcaatcggcg caacattagg tgaagtaagc ttcaaaaaag
      901 ctgcatctga aaaaacttca tggtattaca gtctagtcaa agtggtattt gtacctgcat
      961 tgaatatcgt gattctagca gttttgacgg caacgaatat tctaccagtc aattttgaag
     1021 cactggcaac aatcgttatc atgatggcta caccagctgc aacagtggca gcagcctatg
     1081 ctatcagttt tgatagggag gcacttttag cctccaatgc atccttactg tcaactattt
     1141 ttgctgtggt actgacacct gtatggatcg ttgtattaca aatgattcat ggcataggtt
     1201 tattttcata agaaatggag gaagaaagta tgagaatcgc atgttacggt gttcgtccga
     1261 acgagataga tttttttgaa aaattgaata tttaccatta tgatctcagt ctttatgaag
     1321 aactgttgac acatgacaat atcgtgtcag caaaggacca tgatgctgta ttgttgaggg
     1381 gaaattgtat agcagatgag accaatcttg caaaaatgca ggaatatggg attcgttatg
     1441 tttttacacg gactgtggga gtcaatcata tcgatctaca agcggcagct gattttggta
     1501 tgacagtagc ccgtgtacca tcgtattcgc caaatgcgat agcagagtta tctttgactt
     1561 ttgccatgat gcttttgaga aatactgcgt atacgacgat ccgaacatct ttcaaagatt
     1621 ttcgagtgga tgagcaaatg tttagtcgtg aaatcagaaa ttgcacagta gggatcatag
     1681 gaacaggcag gatagggttg acggaagctg ttttgtttaa gggactagga gccaaagtga
     1741 tcggctacta tattcatcag acagaagctg ctaaaaaagt attgacgttc cactcgcttg
     1801 aagagttatt agccaaaagc gatattgtca gtattcatgt acctcatatc ccaggtgaaa
     1861 acgatcaaat gatcaatgaa ggatttttag ctcaaatgaa aaaaggtagc atcttgatta
     1921 atacagcccg tggagagctt caagataatg aagctatttt aagagctttg aaaagcaatc
     1981 atttagctgg ttttgcaacc gatgtttttg caaatgaaac agaggttttt ttccgatcct
     2041 tcaagccatg ggagacgatt ccagaccctg ctatccagca attagtagaa atgtacccta
     2101 gagttcttgt aaccccgcat gtaggttcaa atacagatga ggcattatca aatatgattt
     2161 cgacaagttt cgagaacttt cgtgaaataa tagaaactgg aaaaacgaaa aatgaggtat
     2221 ctcttcctaa agcccgtcaa ttaagataag aaaacatgga tattcgtcaa taaaatgttt
     2281 aaaaatagtc caagtaaaca gttgttactt ctgtatactt ggactatttt gtatgggata
     2341 attcgatgac tcaacagtaa tctgtgagct ttttccgccc attctttgtc aattcataac
     2401 aggttagcgg ccggccgatt tccaaatatt tgattctttc gttcaatata tcttgttcta
     2461 ctaaaaaatt caaatatttc ttgacggata tacgtgacag tgagcttttt tgagccagtt
     2521 cttttgttga aaaaatagta tcttctttta gaataaatgc acttattttt tttaaagtca
     2581 gttttgacag acctttaggc aaatcgatga atgatggtat ttcgtgaatg ggagtggtgt
     2641 ggttgaatac ttgatcgatc aatttctgat cggctttttc agtcgtttgg attgtctgag
     2701 agaaagcaag atacttttcg atcgccagct gaaaacgttg caaagtgaac ggtttgatca
     2761 aataatctaa ggcaccgtag cggatcacat tctttatggt ttcgatatca tctgcagcag
     2821 tgatcaaaat cactgggata tcatttcctt gctgtctaag ccaagataaa aaatggatac
     2881 cactttcgcc aggcatgtat acatcaagca gcagcagatc tgcgtttttt tgtctgaaat
     2941 atttttttcc ttcttctaca tttctgaaac tttcgattac gttcatatta gggatgcttt
     3001 ccacaaaagt acgattcaat tctgcaacca ttggatcatc ttcgattatc aggacatttg
     3061 tcatcatttt gatcttcctt ttttggtaat tctagataga cgattgtacc gccatttgtt
     3121 tgtttggaaa attctaaaaa tccaccgtgg cgtttgacga ttgaatggat gagattcaat
     3181 ccaaacccac gattgattcc cttcgtcgaa aaacctagcg taaatatttt ttctgagatt
     3241 tcttctgata tcccgacacc gtcatcgcag acggtcacga tgaatacttc agcttctgtg
     3301 tcatagttta aatgaatccg gacctgtccg tttctttcat gtttttgtag cacggcttct
     3361 tttgcattat caagtaagtt ccctaacact tgcaaaagtg aatggatgga gtcatccatc
     3421 tccattttag ggataaaaga atcgctttct aacagcattt caacagattg ttctttggct
     3481 tcgtttattt tgcctaataa aaaaccggca attgcaggta ctttgatcag acttgagact
     3541 tggccaatct cttttttata attttgattt agctgctgga taaaatgggt gacttcttca
     3601 tacttcttca aatcaatcaa accagaaatg acatgaagtt tattcatgaa ttcatgggtt
     3661 tgagctctca tggagtttat atattgtttc gtccccccaa gctcctccat taatttcatt
     3721 acttctgatc gatttcgtaa agttgcgact gctcctaaaa aacggtcatt gctaaaaaga
     3781 ggtgtaacgc tagaaatagt ttctatccca tttaaataca tggattgagt ccgaacggtc
     3841 gtttgatgct caatcgtctc tttaaacaaa acgtcatata gattatcact gatttttttc
     3901 ctacttcgaa atccaatagc tgctctgttt ggtagaaaat gttttttgca ggtgtattga
     3961 tcaagaggat agttttatca gaagagatgg ctaagattcc ttcatctact tcattttcga
     4021 taatcgtttt ttcacttaac tgttctgcta tttcttgtgg ttcaagtcca agcagtactt
     4081 ttttcatttt ttgggcaaga aaaacggcgc ctatgatgcc tacgctaagt ccaataatca
     4141 atgaaaaaac aatcattttt tgtccatctt tgacttgatt gtcaatcgtg ttgtttgtta
     4201 agccaacaca aactgcacca ataatctctt gatcataata aatagggacg aaatagcgga
     4261 agccgaaccc taacattcct tctttttcag agaaaaattc ttgtcctcca atcacttttt
     4321 tcacatcttc atgacttgag aaaggaagac cgatgtaact tgggtctgcg tgagaatatc
     4381 gaatgccttc agggtccatg acaacgataa aatctaaatt cgatgcaatc atgatttcat
     4441 ttgttattcc ttgaatcgca tgtgtcgggt caccagtctg cagctttttt tggatgagtt
     4501 tatcattggc aacgatttta gcaatgctag agattttatc tgacacacta gatcggttca
     4561 tcgaaagaat aaaattcctg atcaatatgg cagaaacaat caaagaaacg aatgtggaga
     4621 aacaaacgac aaggatgatc gtgttctgga gctttaatgg ttttttctta aaaaaaggaa
     4681 acataggcta cctcgaaaga atttattgtg aaaattttaa catgaaaaca aaaatttaac
     4741 aaattgtcaa cgataaacac aaccttccta taaaaaacac cactgagtcg gtaaaagaag
     4801 ctatacagaa ttttcaaaca ttggtatgat agacgtagaa atggaaggag gcgtgtatat
     4861 gataggggga atcgcacttg agacgattta ttggtataca ttgctgattt gtgcaggatt
     4921 ggcagtccta ttgattattt ttggagatgt attcgatttt gatggcccgc ttgatccgat
     4981 gcttattatc ccttggttaa ctttcacaag cttatttggt tttctaggtg agcgtttaac
     5041 agatcaatca tctttatttt tatttattgc tagtggaggc atatcgatag tgttggtatt
     5101 tttgcttaat ttctatatat tgatgccgat gaaacatgcc gaatcaacga tgtcgtcttc
     5161 tgaaaaaact ctggaaggac aagtagctgt tgtgatcaca ccgatccctg tacgaggtat
     5221 gggagaaatt cagttgaaaa gtgttaccgg ttccattagt cgtccagctt gtttttacag
     5281 cccccaagaa cagacagctg agcggggaac gaaagtattg atcattgaga tcaaggaaag
     5341 aatctgttat gtcatgcctt atgaaagcat gataaaagct taaaggagcg tgtgttaaat
     5401 ggaaatacca gttgttttta tcgcgatcgc aatcgcagct ttgattttac tgatgttgct
     5461 gatcgtcttt gtagcgaagt accagacagc aaaaccggat gaagcgttga tcatcagtgg
     5521 aagttattta ggaagcaaaa atgtgcacat tgatgaaagc aataacaaaa tcaaaattgt
     5581 gcgtggaggt ggcgcattcg tcttgccagt ttttcaacgt tcgaatcgga tcagtctatt
     5641 atcgagtaaa ttggacgtct ccacccctga agtgtatacg gaacaaggcg taccggtgat
     5701 gtgtgatggt acttcgatca tcaaaatcgg ttcatctgta gaagagattg ctacagcagc
     5761 agaacagttt ttaggcaaga caagagaaga actggaaaat gaagcaagag aagtattaga
     5821 aggacacttg cgctcgattc ttggttctat gactgtagaa gaaatctatc aaaatcgcga
     5881 taagttcagt caaagcgtac aagaagtcgc ttctgtagac cttgcaaaaa tggggttgat
     5941 catcgtttct ttcactatca aagaggtcag agacaaaaac ggttatcttg actctttagg
     6001 gaaaccaaga atcgcccaag tcaaaagaga tgcagatata gcagaagcgg aagctctaaa
     6061 agaaacgcgt atcaaaaaag ctcaagcaga aaaagaatca caagcagctg aattacagcg
     6121 acaaacagag atcgcagaat cattaaaaga aaaagaactg aaattagcaa cctacaaaca
     6181 agaacaagat gttgctaaag caaaagcaga ccaagcctac aatttagaaa gtgcccgagc
     6241 acaacaacaa gtaatcgaac aggaaatgca gattaaaatc gtagaacgtc aaaaacaaat
     6301 cgaactggaa gaaaaagaaa tcacacgtcg tgaaaagcaa tatgattcgg aagtgaagaa
     6361 aaaagcagat gccgatcggt acgctaaaga acaagaagca caagctcaaa aagtcaaaga
     6421 agtgactgaa gccgaagcag aacgattccg tgtggaagca ctggcagaag cggaagccaa
     6481 taagacacgt ttagctggac aagcagaagc cgaagcagca ctagcaaaag gaaaagcaga
     6541 agccgaagca aaacaaaaga tcgccaatgc cttcaaggaa tatggcgaag cagctgtctt
     6601 gagtatggtt atcgatatgc taccgcaatt gatgcgcgaa gcagcacagc cgctaggaaa
     6661 tatcgaaaaa atctctgttg tcgatacagg aagcagttca ggagaaacca gtggagcgaa
     6721 ccgagtgaca aattatgcca caaatttgct ttcttctact caagaaacac taaaagcgac
     6781 aacaggactt gacttgaagg aaatcgtaga gaatttgtcg acacgtggga ctactagcca
     6841 agtaaatatg tatgaagcgc caaaagaggc agaacaaaac tcgatgaagg aagaataaag
     6901 tagtacactt caccgttcaa tcaaaaatgg aggaagactt tttaaagttc ttctctccat
     6961 ttttttattt tattgcaaaa gaaaattagt cctcgctatt tttcttttgt ttttggatct
     7021 tagcttctat ctcttgtaaa tttgttctta gcaatcgttc tttcttttgg agttcgacca
     7081 aatcttctga tagttcttcc ttcttttctg tttcaggagg acgaagaaag aaattgatac
     7141 cgattgcaat gaatgtccct ataaaagtat ctagtacacg ttggatagca tacaaagcgg
     7201 attcgccttg agggatgctc aacgcaatca gcaacaacgt agctattgcg gaaatgatac
     7261 cggaattatt gttaatacca tctgacacga cgatcacaat aataactaga ataggaagca
     7321 agatcaattc taccaaaaaa tcattgtgaa aatagctttt gacaaaaaaa taaatgatag
     7381 ctaatgtacc acctaatgta ttgccgatga tcctagactt tccaaaagaa acggttgtag
     7441 tcaagtcctg acgcaaagaa aaaacagcag ataatgcagc aatcatcggg attcctcgtt
     7501 gagtcaaatg aaaaaacaag atacataaaa aaacagctaa ggcacttttg atcgtacgca
     7561 tacctagtcg aaaacggcca aattgcatag agattctcct ttttggtctt tttactatca
     7621 tacctaaact tttgtctgat agctagtttt tcattattca agtataatta aaataaaaaa
     7681 gggggaagta aatgcgtata ggaatgcgaa cagtcaaaac agtgatcagt gtcttctttt
     7741 cgatggtcac agcgggtagc ttatcgctgt tgtattggcc agctgcaggg atcattgcat
     7801 tattaagtgt aggaaatacc aagcgctcta cattgcgtac gggcatgaat cgaatcgcag
     7861 cctttatatt agctacggca acagcactgt tcagtttttt tgctgttggg tatactattt
     7921 ttggcttcag tcttttttta ttcctgttca tcccgcttgc ctctcgcttc aaattaaccg
     7981 aagggatagt agtaaattcg gttttggtca ctcattattt agtggaggaa aacatgtctt
     8041 ggcagctgat cggcaatgaa gcgggattaa tggcgattgg attagtattt gctttgcttg
     8101 caaatgttta catgccagat cgtacgaagc agctgaagga aaaccaaata cagatcgaaa
     8161 aagaatttcg aaatattttg agacaaatgg cagaatttct tttatcagaa aataaagaag
     8221 atgtgcagat caaatgcgaa catttactga cattcattcg cgaaagccaa gaagatgcca
     8281 gagaacatca agaaaactac tggctcagac agccgctata ctacgaaact tacttctcta
     8341 tgagaagagc acaggccaat gtgattaaag acatgctgga aaatctagag agaatccagc
     8401 aaccagctta ttatggaaaa catatctatg gtttattgat ttatactgca gaaacatttt
     8461 cagagtcaaa tgatggcaga caaattttaa cacgtattga agaagtttat gtattgtatc
     8521 ggcaaatgcc tctgccgact agtcgccctg aattcgagga tcgagcagaa ttgttccagt
     8581 ttttgcagtc ttttaaaagt tttattgaaa tcaaggcaga attctcccaa caaaaaatcc
     8641 aaaaatagag gttgtgaatt cagctaatat tcaggtcaaa aagctgattt cacaacctct
     8701 tctttaaacg gtgttctcct gtcaactcct cggtcacaag tcacaatatt caacaaacat
     8761 gagaagctgt tttttgaaat tgctccttgt gactcggagc tgaacggtag gctcacaacc
     8821 tctttcttaa acggtgttca aaagctttcc tctgcggtaa taagtccagc caaacgaaaa
     8881 ataggaggag ctatttttgt ttggctgttc ttattacttg atgcagaaca gctttttcac
     8941 aaccttttaa aattacatat ttttccatag aacttgcatt tgatccaaga tttcgatgac
     9001 atcttttgtc aagaagagag agcgattggg caagtcacct tcaatcatgt gtaccatatt
     9061 ctttatttcg taattcattg cttcagatgt attcccgctt tcgatgaatt cctttgtacc
     9121 atctgtaaat aagatctccg cacgatcagc acgcgggtaa tcagcaatcg tcacataacc
     9181 gttctcaaag gcaacgatac cgacttttgg catttttgcc tgaaaagtca agctgacagc
     9241 agcaagttca ttttctttgt tacgcaagat agtgacggat tgttcgtcca cgcctgtttc
     9301 aaaaggaacc attgtagagg caactacttc aggttgagag ctcaaaaaga aacgagcgaa
     9361 agatacagca tacgtaccga tatccaacag agctcctcca gctaattctg gattgaagaa
     9421 ccggttttta gggtctggtt ctttgtaact gccgaaaggt gcttggatca tttttaaagc
     9481 ccccagtttt cctgtatcca ttattgagcg taactgctga taaagtggca tgttgaagat
     9541 tgtcatcgct tctgctaaga tcaaattctt ttcttctgct aagcgcatag cgtcagccag
     9601 ttctttttta ttcatcgtga tggctttttc acatagaacg tgtttgcctg cttccaatgc
     9661 tgccaagata tggtcgatat gctgtctatt tggtacagca atgtacacga tgtcgatttc
     9721 agcatcgtct aacatttctt gatagcttcc gtaagctttt ggaatattgt aacggtgagc
     9781 gaagttttcc gctttttctg aagttctgga agcaactgct gttagttcgc tcgtctcttg
     9841 attgaagctt tcggcaaact catgtgcgat ggtaccaaga ccaacgattc cccattgata
     9901 ttttttcatc tgaaaacgct ccttcatagt tggattgagt ttcttgtctg tctattatta
     9961 taacaaaaat cacgaagaat aaagaggaga ggacttgaaa cattaaaaaa aatgaaagca
    10021 gcgatttaag aggtgctttt tgatcaaaac ttaagtagaa tagttaaaag gaggggataa
    10081 acgtgcatca agtatatatt gatcttatta tgagtgtatt attagaacag tttgaaactg
    10141 aaaaaaattt tttagatgaa tacttgctga tcagtccaga acaatggcaa aaatggaaag
    10201 atggcgagaa aaatctgcca tctgaagcga tgcagaaagt aaaaaatctt ttcactgatt
    10261 atgaatggat gctaacgcaa aagattttgc gtcaaacgat tatttttccc gaaaaacgaa
    10321 acgttgccgt tgcagagtac aagcaaatca aaacacgcat cgcgcaaaaa tggcttagca
    10381 gcaaagcagc aaaagtcgag ctgatccctt tgaaaaataa tcagcaggct ggtagatacc
    10441 ttgacttgaa agtaagtatt caatatgatg aatggggcta tgatgatatt ttgaattttc
    10501 gtctgccagc agatgttcaa aaacagatcg aaggagaaaa aatcgaactt ctcgattggg
    10561 tgaatgaaaa tctggaagaa acttacgttc atgaggcgaa tggggaacgt gaagaacaac
    10621 gaaaggattt ttcaagtgaa taaattttta ggatttggag cagttgtgat tatgatcgca
    10681 gcaatgggct atgttatttt tagcgatgat gattcgcatg ttcaagccgg caatcaagca
    10741 gtcgaacgaa caagcaccaa aacaactgct agtaaagaaa agaacagtca aacaaccagc
    10801 agcaaggtaa aggacaaaga aacaaaagat cgtacgtcca aacaattgcc agatgttaaa
    10861 acagacgatt ggaagctagt tttggttggt ccagatcaca aattagaaaa agaaattgat
    10921 gagtctactc aattggcatc attaagtaac ggatacttga tcgacaaacg cattgctcca
    10981 gaatatgaag catttgccaa ggctgctgaa gcagctggat ttccattagt gatggtctca
    11041 gcttaccggt ctgtatcatc ccaacaacaa gttttcgaac aaaatgtcca agatgtgatg
    11101 agtcgtcaag gtgtatcaga agaggaggcg acaaagatta ctaaagaaac gattacggag
    11161 ccaggataca gcgaacacca cacaggtctg gcagtcgatg tcgtcgatca aaactggtac
    11221 aacagttatc cttctactgt attggatgca agttacggag atcagcctgg agctaaatgg
    11281 atcgcagata atgctgcgca gtatggattt atcgttcgtt atccaaaagg acacgaagat
    11341 ataactaaga tcacatatga accttggcac ttacgttatg tcggtaaaga aaacgctgag
    11401 tatatcacca aacaccaatt gacgctagaa gaatatctga atgaattaaa tgaaaagtag
    11461 gaattgatca tggcgaaaaa aaagtggaaa aagcaaaagc gcaagaatat ccgttggcca
    11521 gcagtggttg ccggtgtagc agtgatactc ttagcctttg ttttttcctt gaagaatctg
    11581 tcttctcctt ttactgataa tcagcaagaa aatgaagcgc aatcccatca gcaatttatt
    11641 gaacggcttg ttccgcatgc ccaagaacta caagatggtt atggagtgct tcctagtatc
    11701 attttaggac aagctatatt agaatcaaat tggggaaaaa gtaccttggc tagcaaatac
    11761 aataatcttt tcgggatcaa ggcttatggg gatcagaaga aagtaagcct ggaaacaaag
    11821 gaatttgtta acgaagaatg gataactatc caaggagact tcaaagtgta tgattcatgg
    11881 gaacagtcca tggatgacca tacacaactg ttcgtccaag gagtagattg gaatcctgcg
    11941 ctgtatgaaa aagtgattac ggccaccaac tatcaggaag ccgcacaagc attgcaagat
    12001 gcaggttatg cgacagaccc cggttatgcg caaaaaatca tccaggtcat cgagacgtat
    12061 caattgaatc agtatgaccg gagatagcaa aggagaagtg gctgatggca gaacaattta
    12121 cgccagaaat catgacggaa ttgagaaaag atatcgtaag agtaccggaa atcattttag
    12181 aagcaagcgg gatcaagata tttggaaaat tgatccgttc gatcatcttt actacggata
    12241 ttgcgatcat acgtaataca aatgcgaatg cagtaattgc tgtgtatcct tttacacctc
    12301 atccagcgat tactaaaagc attattgagg cagctgacat tccagttttc tccggtgtag
    12361 gtggtggttt gacacaaggt gctcgttctt cctacatgag catgttcgca gaagcgcaag
    12421 gttcgttagg ggtcgttttg aacggtccta cgcctttaga gacagtaaaa gaagtttgtc
    12481 gagtagttga tattccagtt atcagtacgg taacgtcgaa atatacagaa atagatgaaa
    12541 agttagcagc tggtatttcg attatcaata tcagtgcagg taaagaaact gcagaagcag
    12601 tacgccattt tcgtaaaaaa tatcctgaac ttcctatcat tgcgacaggt ggtccaacgg
    12661 aagaaagtat tgctgagacc attcaagcag gagcaaatgc catcacatat acgccaccaa
    12721 gtagcggaga gctttttagt cgtaaaatgg aaaaatatcg ggaaactgag aaaaagaatc
    12781 atgaataaca ggtgagaatc aaaagacgag gaagagcaga tagtggctct tcctcgtctt
    12841 ttgtactcca gtactatttg ttcagaattc aaaaaaaaga gaaatttttt tgttttttta
    12901 cctgtaatgt acataagaag agttaaaacc ttttgttatt attagcattc taacaaaaaa
    12961 atgtcttgat ttattgaagc gctttctata gaatgaaaaa cgaataaaaa ctaaaaaagg
    13021 cacccgacaa tttagtagca gctaaattgt cggggcttga aaagtcagcg ggaactgacc
    13081 aatcaagttg ccatagtcaa tgcttgtgca tcgacgtgta tattgtacct aatttcatac
    13141 agaattacta gttatttttc tgttttttag ggaagagcgc acacgaagaa gcatgcttat
    13201 ttagctatgt caaggatatt gggcagttgt ctgatatcct tttttctttg cgtaattatc
    13261 ctcccatcat tgaagcaaga agtgttttta gcgatgaaag aagaatcagc actatctaat
    13321 ttttcttgaa agtattgagt tgttcatcct aggcagaacg ataaggcaag tcttggtttt
    13381 tattcccctt gaaaaagatc gtttaataaa tatgttctgt ataaaaatac agtatattga
    13441 aaaataacaa tggaagtaga ggtgcagaga atgaagaaaa gaatgagaat catcttagct
    13501 ttaagtgtta tgttattctt cttgacggct tgtgggcaag aagatgacaa aaaaatcacg
    13561 ctgaacatgg cttggtgggg ttcgcaagtc cgacacgatg caacagtaaa agtaatcgag
    13621 ctttatgaag aaaaaaatcc ccatgtgacg atcgattatg aattttatga ttatgaagga
    13681 tattacacaa aattaggtac actagcagca tcagatgata tctgggacat tttccaactg
    13741 aacaatcaat ttcctcaata catcaatcag attgaaccat tagatgaata tgtggagcaa
    13801 gggataattg atatttctaa tgcagatgaa tcctatttag caacgacgac ttacgacggg
    13861 caattagttg gactgtctaa cggggtgaat tcgtttgcga ttgcttacaa taaaaatata
    13921 tttgaacaat taaatatccc tgaaccagct tcaaattgga catgggatga atttgaacaa
    13981 atcagctatc aaatcactga agaattagga atctatgcta tttcaagatt cgaagatttt
    14041 atagctggct gtattattca aataccacaa gttgagaaag gattgaattt ttataatcgg
    14101 gaagatctat ctaacagctt gggatttgaa aatccagact atctaacaga ttttttccag
    14161 ctgcgtaaaa atctggtaga caaaggggcc catccagaac caggtggtgg agctgcaagt
    14221 acgacggatc tgtcttttca ggcggttagg gatagagaag cggcaatggt gtttctatca
    14281 agtaaccagt tgacagaaat attgtcaggg gctcctgaag atatggagat tcagttgatt
    14341 aatccacctc gcagaaaagc agatggagaa tctggtatcc ctttacgttc ttcgcaaatg
    14401 ctgagtatgg caaaaagctc agcccataaa gaagaagctg ctaagtttat tgatttcttt
    14461 caaaacagtg aagaagccaa tgaaatttta aaaggagaac gtggtgtacc aatcatgtcg
    14521 aatattcgag aacagctcgc tcgtgcagat gatgcaactt tgcaagcgac atttgattat
    14581 ttagaaatga tttccgatat ggacaacggc gaagtgaatg tctttgatag tgctttgaat
    14641 ccggaaattc aagaccaata caatctttta gttgaaaaag tcatttatga agaagtaaca
    14701 gcagaagaag cagcagagag tctttatgag tttgcgtcaa acattctagg atagcagcag
    14761 gaggaaggca tgaaaaaaga aaaactaaaa cggttcttgg atcaagacaa tgtggtcggt
    14821 tacgtatttg cttctccatt catcctagga tttctattga taacagtgat accgatgatc
    14881 ttgtcacttt attattcgtt caccgattat cgtttgggaa atccagtctc atggatcggc
    14941 ttggataatt atataaagat gctgagtgat gcccgttttt tgaactccat ccgagtcact
    15001 tttctctatg tatttgcatc tgtacctgtg aaactgatct ttggtctatt gattgcttat
    15061 cttttaacga ggaatatcaa aggaacgact ttctttcgtt ctttgtatta tgtgcctagt
    15121 ttgatcggtg gcagtatttc tatcgctcta gtttggcggg agttgttttc taaaaacggg
    15181 ttagtgaata ttttcctgga acgattaggc gcacctgcgc tttcctggtt tagcgatcaa
    15241 aaactggtca tgatccctct tgttttgatg tctgcttggc aattcggttc ggcaatgatc
    15301 atctttgctg caggtatcaa agagatccca ggctcgtatt atgaagcggc agagatcgat
    15361 ggagcgaaca aatggcagac gttttacaag atcacgttac ctcttctttc gccgatcatt
    15421 ttgtataact tggttatgca gacaatcgcg gcgtttatga cttttacgca ggcatttatc
    15481 attacccaag gtggtccgaa tgatgccacg aacttttatg ctctttatgt gtataaccaa
    15541 gctttttctt ttaattctat ggggtatgct agtgctattt cgtggatcat gctgttgatt
    15601 atgggagctg tcacctttct gattttcaaa tcatcaaaaa aatgggtcgt tgtgtgaatg
    15661 agaggaggaa gaaatgaata atacagtaac gaaatggttt caatacggtt ttattttgct
    15721 attaggtcta gtcatgattt atccggtctt atggatgatc gcaggttctt ttaaaacgga
    15781 tcaagagatt atgagtggtt cgctgaattt gattccagag acttttcaat gggaaaatta
    15841 cgcaaaagga tgggcggggt ttgctggaat ttcatttttt actttcttta ggaattcgtt
    15901 tgtcatctct gcagtttcga cgatagggac agttctgagc tcgacttgta ttgcttacgc
    15961 attatcgaga atcgatttca aaggaaaaag attctggttc gtcgtcatgt tagtaacgat
    16021 gatgattcct gcacaagtga ttttgattcc gcagtttatt atttacaatc ggctgaattt
    16081 ggttgggacg tatgtgccgc tgattttacc acattttttt ggacaagcat ttttcattta
    16141 ccagatcatg caattcatgg tcagcatccc caaagagtta gatgaatcag cgattattga
    16201 cggatgcagc aagtatagtg tctttaccaa aattattttt cctttgctga aaccttcgat
    16261 catcacgacg atcatcatcc agttttattg gaaatgggac gacttcatgg gaccattgat
    16321 ttatttaaac aagccgagat cttacacggt atcgattgcc atcaaattat ttgcagacgc
    16381 tggatctagt acgacttacg cgagtatgtt tgcgatgtct acgttgtcgc tgctaccggt
    16441 ttttctgatt ttcttattct tcaataaata tcttgtccag gggatcagta caagcggtct
    16501 gaagggctga atatgaaaaa gccaatagaa gagatgtttc tttacaagct caactactat
    16561 gtctgtcgga tttttttaac cagtcttatc agtaatgctc ttttcgcttt agttctagga
    16621 tgtttgttca ctttaggatt agtgctgtct gctcgtgttg tctatctgat ttattttttg
    16681 atgatgtatc cttcttatta tctatctgtc cattacttgg cagaaaaaaa ggtatgttgg
    16741 aggaaaggaa aaatcaaacg gatgtgtttc atcattacgt tgtttcagct gtttgtcatt
    16801 atttttgcag ttgattggta tttattagtg ggaaagattg gagcttggta tctgattcct
    16861 tttctattgt gtctgttgct ttttgtatcc catagttttt ttagtacgct aattgatatc
    16921 tgcaaagaag ataaagcaga tagtcttgtt tatttgatca aaaggaatat ctggctgttg
    16981 tcaaaaaacg tcaaggggtt tctgtggtat ttatgccttt tgtatggact gttctggtgt
    17041 atacagcatg attttttact cactgcatta ctgtatccag ggctgccatt tgtcacagta
    17101 ttttgcttaa aagaaaagga gaatgacttt aaatgaagaa aaaatatgta caagtcggac
    17161 ttggtgggag agcgcgtttt ttttatgagg caattgcctc tacgtatcat caaacttgtg
    17221 aactagtcgg tttttgtgat gtatctcaaa caaggatgga ttatgcaaat cggatacttg
    17281 tgaacaagta tggacagaaa aaagtaaaga catgtatgcc atcacaattt gagcaactac
    17341 tggatgacgt acggccggct gaagtcatta ttacgtcagt agatcgaacg catcatgatt
    17401 atatcattcg tgcaatgaaa aaaggatatg atgttatttg cgaaaaacct ctgactatcg
    17461 atgaggaaaa agctcaagaa ataataacgg tccaaaaaca gacgggaaga agcctgcgag
    17521 tcacttttaa ttatcgttat gcaccgtatc acacgaagat aaaggaactg atagaaagtg
    17581 atgtgattgg tgatgtgttt tctatccact tcgaatggct gttaaatacg caacacgggg
    17641 cagattattt cagaagatgg catcgaaata agcacaatag cggcgggctt cttgttcata
    17701 aatctaccca tcattttgat ctagtgaatt tttggttgaa cagccgtccc caaaaggtat
    17761 ttgcattcgg tggattaaac ttttatggga tgcataatgc ggagaaacgc ggagtagaaa
    17821 tattttacag tcgatgctat ggaagcgaac tagctaaagc tgatccattt gctatagacc
    17881 tgtcagccaa tgaggaattg cgagaaatgt atttagaagc agaaaaagac agtggatata
    17941 ttcgtgaccg cagtgtattt tccgatgata tctctattga agatacacta ggcgtaacgg
    18001 tcaaatatga aactggtgcg attttgacgt attcgctaaa cgcgtatatg ccgtgggaag
    18061 gattcaatgt ttctttcaat ggcagcaaag gacggatcga aatgaaagtg atcgaaaagt
    18121 cttacatcaa tgcaggtgga gataaaaagg atgaaggagc agccgttctt cagtccatcc
    18181 atgtctatcc gatgttcggt gagccatatg aggtaatcgt cgaacaagaa gcgggcggac
    18241 atggcggagg agatccgcgt ttattagatg atctatttgg tgaagaaaaa gaagaagatc
    18301 cgtggaatcg ggcagcaact cacgtagatg gtattttgtc gattttgaca ggaatcgcag
    18361 caaatcattc tattgcttca ggaaaagcag tagtgattga cgagcttgtc agcttaaaag
    18421 aataagaata gatttacgga aattacttcc cgtagtttat aaaatcttgc cttattgccg
    18481 ataggctgtc ttttgaacac tatttattcg gaaaaagggg ctatgacatg ctttttgtca
    18541 tgccttcttt ttatgtgggc tgctttttta gataggagaa aataaaaata actatttaaa
    18601 cccgaacaaa aaggaataat gcattaaaaa tcattagatt ttacaaaaaa ataagtaaac
    18661 cacgttgtca gtttcagaaa gtagtgttag actgttttca atatttgaaa caacattttt
    18721 tattcaaata tggcaaactg ccttcacgtg caaaacagtt gcaagaaaat gaatttacac
    18781 tattattagt tttacatacc tacttatata tcgtcataat atggatgaca gtttctagcc
    18841 agtaccgtaa atgctggact ataagtaaaa gattggctat ttcacccttc ttttcttatg
    18901 ataaagtgga gggtgttttt ctttaacaga aacatagtag gtttttgcac aaaagcggtt
    18961 atttcggtat taataaatga taaaggagca aataaagtga aagaattagt tgaacgtatt
    19021 caaaaagacg gacgtatatt aggcgagggc gtattaaaag tcgacagctt cgtcactcac
    19081 caagtagacc ctgtattgat ggaacaaatg ggaaaacggt ttgcagaagt atttaaagaa
    19141 caaggaatca cgaaagttgt gaccattgaa gcttctggga tcgcaccagc tttatttgct
    19201 gcaagagaat tagatgttcc aatgatcttc gctagaaaag caaaaagttt gacgatggat
    19261 gaagaattat tgacagcttc tgtttattct tttacgaaac aagtgacaag tacgatttct
    19321 atttctcgta aatttttatc ttcagaagac aaagtattga ttatcgacga tttcttggca
    19381 aacggacaag cggcaaaagg attgatcgaa ttatgccagc aagctggagc gcaagtagaa
    19441 ggaatcggga tcgtcatcga aaagtctttc caagatggac gtcagttact tgaagaaatg
    19501 ggattgagag tcgtttctct tgcgcgtatt gcttccttga cgaatggaca agttgagttt
    19561 cttgaggagg acgcataatc gtggaaaaag aaacacaaaa tggaaaagct gcggttttag
    19621 ggctgcagca tctgctagcg atgtatgcag gagcagtagc ggtgcctctt ttgatcggta
    19681 caggactagg ctttaatcaa gaacagatga cttatttgat ttcaattgat atctttatgt
    19741 gtggattagc gacattattg caattgacag ttaaccgatt tttcggaatt ggcttgcctg
    19801 tcgttttagg atgtgcgatc caagcagtag ctccactgat cttgatcgga accaatgaag
    19861 gagtaggagc tatctacgga tctattatcg cttctgggat ctttgttgtg ttagtttctg
    19921 gtgtcttttc taaaattaaa aaactattcc ctcctatagt aacaggaacg gttatcaccg
    19981 ttattggttt gactttgatt cctgtagcaa tcgagaaaat gggtggaggt aatgcaacag
    20041 cagctgattt tggtgacaaa acaaatctgc tacttgcatt tgtgacgatt ctcctaattg
    20101 taggcgtgca aatgctggca aaagggttca ttcgttcaat cgcggtattg attggtttag
    20161 tcggaggaag catcttagct gctttcatgg gaatgattga tctgagcgcg attggagatg
    20221 cgccgttgtt ccatgttcca caaccctttt attttggtaa accaactttc gacgtatggt
    20281 cgattttact aatgatcatc atttccatgg tcagcatggt agaatcaaca ggtgtatatt
    20341 ttgcacttgg tgacattact gggaaaaatg ttggagaaga agaattgaaa aagggatatc
    20401 gtgcagaagg acttgccgtt atcttaggcg gtattttcaa tacattccct tatactggct
    20461 tttctcaaaa tgtcggattg gttcaacttt cgggaatcaa aacaagaaaa cccatctatt
    20521 tctctgcatt cttcttgatt gttttaggat tattccctaa aatcggtgcg ttagcacaaa
    20581 tcatccctga gccggtactt ggtggaggaa tgttagtcat gttcgggatg gtggcagtcc
    20641 aaggaatccg tatgctgttg gaagttgatt tcagcaatga taaaaatcta ttgattgttg
    20701 ctgtttctgt tggatttggg ctgggtttca atgttacgcc gacattattc agtcaaatgc
    20761 cgcaaacatt gcaaatgttc actggaaatg gcatcgtaat gagtagcatt acggctatca
    20821 tattgaattt gatctttaat ggattgaaaa aagatgaaga aatattggaa gaagccttca
    20881 agaagtaata gagcaaaaga aaggttgtga aatcagcgtt ttgacctgat tgttagagaa
    20941 acaaacggaa aaatagttcc tcgtattttg ccgtttgttt gagctaatac cgagggtcag
    21001 ctgattgaac accgttgaag gaagaggtcg tgagcctgcc gttcatctcc gagtcacaag
    21061 gaacaatttc aaaaaaaagc ttctcatgtt tgttgaatat tgttccttgt gaccgaggag
    21121 ttggcaggag aacaccgttt atccataaaa aggaatgtga cctaactttt gtcacattcc
    21181 ttttttttat ctttaataaa cacgaacaat aaaatgtttt tctttgttaa cattcgaaat
    21241 ttctttgaca tcaaaaaaag tgattgttaa aatatgaatg tagaaaaact gggaggaaaa
    21301 acaatgacag caaaaatctc tgtgattatg gggagtactt cagattggga aacaatgaaa
    21361 gaagcatgtc aaatattgga tgaattcggt gtgtcttatg aaaaaaaggt cgtttctgct
    21421 catcgaaccc cagatttgat gtttgaatat gcacaaaacg ctcgaaaaaa aggaatcaaa
    21481 atcattattg caggagcagg gggagccgcg catctgccgg gtatggtcgc atcaaaaaca
    21541 actttgccgg ttatcggtgt accggtccaa tcacgaacat taaatggttt ggattcgctt
    21601 ctttcgattg tccaaatgcc tggaggagta cctgtagcta ctacagcaat cggaaaagcg
    21661 ggagcaatta atgctggact acttgcgata cagatgcttt ccatgtatga tttagaattg
    21721 gaggctaaat tggctgaaag acgttcaatg ttggctaaaa ctgttataga aagtagtgat
    21781 caacttggtt aaacctttgt tgcctggttc aacgatcggg atcgtcggtg gcggtcaatt
    21841 aggtcgtatg atggcgatta gtgcaaaaga aatgggcttt aaagtaggtg tgctggatcc
    21901 tgtgagcgat tgtccagccg cacaagttgc agattggcac attgaaagtg tctatgatga
    21961 cacctttgcg ctgaaagagc ttgccagaag aacagatgtc attacctatg aattcgaaaa
    22021 cgtcagtgta gaggcgttaa atgcgatttt acccatgtca tttattcctc aagggacaga
    22081 cttgcttgcg attacgcaag accgcctgtt agaaaaatct tttttggaaa cgaataacat
    22141 cgtgattgct ccttatgcaa cgatcgtcag tccgacggat atccaagatg cgattgacgg
    22201 gatcggctat ccttgtgttt tgaaaaccac tcgaggcggc tatgatggca aggggcagta
    22261 tgttttgaaa agtcgggcgg atctagctcc tgccatggac cttttaagag aaggaacctg
    22321 tgttttagaa gcatggatcc cgtttgaaaa agagatttcg atcatggtgg caggaaatgg
    22381 tcaaggagat ttcacgactt ttccggtcgt ggaaaacatc caccacaaca atattcttca
    22441 tgaaacgatt gctccagccg cgattgatca ggatgtgatc gaggaggctg agcgtattgc
    22501 ccgtgtgatt gcagaagcag tgagcctttc aggtgtttta ggggtagaaa tgtttttaac
    22561 aaaaacaggc gggctatatg tgaatgaatt agctcctcgt cctcacaatt ctggacatta
    22621 ttctattgaa gcttgttcta tgagtcagtt cgatgcccat attcgaggta tttgtggttg
    22681 gccattagga gaaaaagtac gtttgataag caatgcagta atggtcaatg ttttgggaga
    22741 acaactgctg gaaagctatc gcttgattga gaataagcca gactggcaat tccatttcta
    22801 tggaaaaaaa caagcaaaaa aaggtcgcaa gatgggacat atcactatct tgacagaaga
    22861 catccagcaa acgctggaag aaatcaaaca aacgaatatt tgggattaga ggagaaaaaa
    22921 catgttagaa cgttatacac gccctgaaat ggggaatatc tggacggaag agaacaaata
    22981 ccgtgcgtgg ctcgaagtcg agattttagc agatgaagct tgggcagaac ttggtgaaat
    23041 cccgcaagaa gatgtgaaaa aaattcgtga gcatgcatca tttgatatcg atcggatctt
    23101 ggaaatcgaa aaattaacac gccatgatgt cgttgcgttt acacgagcgg tttctgaaac
    23161 attgggagaa gaaagaaaat gggtccatta tggtctaaca agtacggatg tcgtagatac
    23221 tgcttatggc tatctcatca agcaagcaaa tgatatttta cgggaagact tgaaacgttt
    23281 tacggaaatc attggcgaaa aagcaaaaga acacaaatat acagtgatga tgggtcggac
    23341 acacggtgtc catgctgaac caactacttt tggattgaaa cttgccacat ggtattcaga
    23401 aatgaaacgg aacatcgaac gatttgaaca tgcggcaaaa ggagtagaag caggaaaaat
    23461 ctcaggagca gtgggaacgt tcgcaaatat cccgccattt attgaagagt atgtatgtaa
    23521 acaattgggg atccgtccac aagaaatctc tactcaagtt ctccctcggg atctacatgc
    23581 tgaatatttc tcagcgatgg cgcttattgc tacaagtatt gaacgttttg caacagagat
    23641 acgcggattg caaaaatccg aaacacgtga agtagaagaa ttttttgcga aaggtcaaaa
    23701 aggttcttct gctatgccgc acaaaaggaa tccgatcggt tcagaaaata tggctggtct
    23761 agccagagtg gtgcgcggac acatggtcac tgcctatgaa aatgtcacat tatggcatga
    23821 aagagatatt tctcattctt cagcagaacg aatcatcttg cctgatacca cgattttatt
    23881 gaattacatg ttaaatcgtt ttggcaatat cgttaaaaat ctaacggtct ttcctgaaaa
    23941 catgaagcgg aatatgtctg caacatttgg tttgatttat agccagcgcg ttatgctgaa
    24001 attgatcgat aagggaatga caagagaaga agcttatgat cttgttcagc caaaaactgc
    24061 gtacgcttgg gacaaccaag tgcagttccg cccgctgtta gaagaagatc caaccatcac
    24121 atcggtatta tctaaagaag aaatagacga tgcctttgat tatcatcatc atttgaaaaa
    24181 cgttgacgtg atattcaaac gagtaggttt ggaataaaga agagtgagtt gcaaaattca
    24241 attaaaatag aatagcaaaa ataatcgagt agaggggaaa gccaactgac cttccgcccc
    24301 tctcacacca ccgtacgtac ggacccgtat acggcggttc aataagttga gtgtacgaac
    24361 tggtacttca aggagatgtc ctcatatcct tggcgggcca gttctttgtc tgttaatgat
    24421 cgatgaagaa tatgactttt ggagactgac caaatacctt ttcttgtatt tgaccattca
    24481 tacgctttcg ctttatcgat ccctaaacga atcagatttt ttcttttggt tcttggattc
    24541 ttccattgtt tccaaatata ttgtctgatt cttcgcttca accaaccgtt taactccctc
    24601 atgaattctt tcatctcacc aattccatag tagttgatcc aaccagtcat tagttgcttg
    24661 atttctttta aaataagttg gatacttctt ccacggtttc ttttagtgag ttgtttgagc
    24721 ttgcttttca cacgctgttt tgcttttgcg tgagggcgaa ttttaatacc tttctttgtt
    24781 ggcagaatgc agaatccaag aaactttcgt ttcaatggac ttcctaccgc actcttttct
    24841 cgatttaccg tcaactttag ttgttcttcg agaaattgaa tggatttctt catcacacgc
    24901 tgtcctgctc gtttgcttct aacatagata ttgcagtcat cggcgtatcg aacaaattta
    24961 tgtcctagat tttctagcac ttgatcaaat tcgttcaggt agatgttact taacagggga
    25021 gagagattgc ctccttgggg cgttccttct tcagttgttg tgatgagtcc attttccatt
    25081 acaccactca ttaagtattg acggatcagt tttaggactt gtttgtcctt tactttccgc
    25141 tcaatgaaat acatcagctt atcgtgattt acggtgtcaa agtaggcttt catatcaatg
    25201 tccaccacat atcggtaacc ttgttcataa taagattttg ctttcttcac tgcgtcatgt
    25261 gcgctgcgat ttgggcgaaa cccataacta ttatctgaga attctggttc aaatagcggt
    25321 tgtaacactt gattgattgc ctgttgaagc atacgatcaa taaccgtggg aattcctagt
    25381 tttcttacac cgccgtttgg tttcggtatt tctactcgca aaacaggctg aggtttatag
    25441 ttcccttggc gtaaattgga tagtaattcc tcgcggtgct ctttcaagta aggaagcagt
    25501 tgatcgacgg tcatcccatc tgcaccagcc gcccctttat ttctgactac ttgaagatac
    25561 gcttgattga gattattccg atctagaatt ctcccaaaca gattttctac accatcttgt
    25621 ttcctctgtt caccgcaaga agtgctgcgc acttcatcat acccttcgtg ttccacacta
    25681 gctctttgat gatagccaag ttttcttgtt ttctgcggtc gtcgcatctt ctcacacctc
    25741 ctaaattatt caagattctt attgttcagt ccttcgtaac ggtcagtgtc gttactacta
    25801 tgacctcggc tgacttctca tgattcacca tcatgtcgcc atgatcgttg tgctggtttg
    25861 ttttcattca acgcccacaa caccctcatg agatctcccc cggtaagagt gaaaactttc
    25921 ctcccatgta actgctagat ttactgtata ggtttcgggc agtattggac tttgtcttgt
    25981 gatgaagact tatccgacct aattcagcct tgtatctagt ttctgttcgt cagttcagga
    26041 gtttgcgtcc gacttccttc agccacaacc tcacgattgc cgccttgtct ttcgctaaca
    26101 gttcctactg ccaagcctgt agtggacttt caccaccaag ttttcaccca tgcagggcgc
    26161 acaccaaaaa agaagcagat ccgttagcgg ttctgcttct tttagtttat tatattttct
    26221 tatcaataat aggaacctga ttttaaaagc ggctacctct ttaccgtgcc tctttacata
    26281 caaaaaatag aggaattaag cgtaaatggc ttggctatta taactaaaat gctggttatg
    26341 gagatgttgc agcaagtttt cgagaaaagc gtattccatc tcttgtccat tgaataagat
    26401 ctggatacga taatgatttt tgaaacgctt ctgttcatga atctgactga ttgaaagttc
    26461 gcctttgtgt tctgtctgat aaagaaaagt ccttttacgg cattcagcac agcgcttggt
    26521 tgctcggcgg atttttcgga atgtataaaa actagtatct ttattgcata aataaacgtc
    26581 tttgatcgac agcaaatcat tatatagaca ggaacgttct tcagctgtta attctgataa
    26641 aaaaagctga ccttgtttta ttgcatcttc catcggcaag tgcctcctcg aacccattat
    26701 ccaaattttt agttaattct aatataccat cattaagtat aaatgtaaac gcttgttgat
    26761 ggtataagat tttcgtttct gataaaacac gaacattaaa agaatctaat gccttaaatg
    26821 tacatatttt tgttgattta taaaaagatg attgctaaaa tttaaagtga aaaaacgaac
    26881 aaaaaacgat gtatttgctt ttaatgtaaa taaaaaggag agacgtacat ggagaagaaa
    26941 gaacttttgt atgaaggaaa agccaaaaaa atatatctta cttctgatga gaacttgatt
    27001 tggatagaat atttagatca agcaactgcg ttgaatggcg cgaggaaaga ccagataagt
    27061 ggaaaaggag aattgaataa tcaaatcaca agtgcaattt tccgttatct gactcaaaga
    27121 ggaataaaaa atcattttat tgaacaattg tctaaaaccg aacaattagc aaaaaaagta
    27181 caaattatcc ctctggaagt ggttatccga aatattgcag caggaagttt ctcaaaacgt
    27241 ctaggtgttc ccgaaggtaa agaattcatc aaaccaatca ttgaattcta ctataaggat
    27301 gaccagttgg atgatccatt tatcaatgaa gagcatatct atttcttaca acttgcaaag
    27361 ccggaagaaa tcagtgagct gaaagcccaa gcgttggcta ttaatgaaat tttgaccgaa
    27421 ttatttgcta aggtcggttt ggttttagta gatttcaagc tagaatttgg ccggtcgaat
    27481 ggacaaattt tgcttgcgga tgaagtaaca ccggatactt gccgattatg ggatgaacgt
    27541 acgaatgaac atatggacaa agacgtttac cgcagagatc taggtgattt gatcccagtc
    27601 tatcaagaag tatataaccg tctatcggaa ctaactgaag aaaaggagcg agtatgatgt
    27661 atttcgtaaa agtatatgta acctataaag attcagtgtt agatcctcaa ggggaggcag
    27721 taaaaaaagc agtccatcgt atgggatatg aaacaatcga agatatccga ataggaaaat
    27781 actttgagat acaacttgct gatgcagaag aaccaatcga tacagtgatt gaaacgattt
    27841 gtgacaagct gcttgcaaat gtaaatatgg aaacataccg atatgaaatc aaaaaaatgg
    27901 aggaagtata acatgaaatt tgcggtcatc gtttttccag gttcaaattg tgacgcagat
    27961 atgttatggg cagttcgcga gatcatgggc gctgatgccg aatttgtacg gcatgatgag
    28021 tcctctttag aaggatttga tggggtttta ctgccgggag gattctccta tggtgactat
    28081 ttgagatgcg gtgcgattgc tcggttttct acaatcatgg aagaagtgat tcgttttgct
    28141 gaagaaggga aaccagtatt cggtacatgc aatggattcc agatattgac agaagcagga
    28201 cttttgccag gtgtactgag acgaaatgag tctttgcatt ttatttgcaa aactgtacca
    28261 ttgaaagtca accccaagac ggcctttact tcagagtatg aagccgacga aataatctat
    28321 cttccagttg ctcatgggga aggaaattat ttctgtgacg aagaaacact tcaagaacta
    28381 aaaaaaaata atcagattgc ctttacttat aatgacaaca tcaacggcag cgtggaaaac
    28441 attgcaggga ttacgaacaa agcagggaat gtgttaggaa tgatgcctca tccagaacgt
    28501 gcagtagaag acttgctagg atcagaagat gggaaacggt tctttgcttc cattttaaaa
    28561 aacttcggaa aggtgaccgt atagatgaaa acattgaaag aaccgacagc tgaagagatc
    28621 aagaaaaaaa gaatctatgc cgaatgggga ttgactgatg aagaatatcg aatgatcgaa
    28681 gaagatatct taggaagaat gcctaattat acggaaactg gactgttttc tgttatgtgg
    28741 agcgaacatt gttcctataa aaattctaaa ccggttctac gcaaatttcc tactagtgga
    28801 cctcatgtgt tgcaaggccc tggagaaggc gcaggcatcg tcgacatcgg tgatggacta
    28861 gcagttgtct tcaaagcaga aagtcacaat catccttcag ccgtggagcc ttatgaagga
    28921 gctgcgacag gagttggcgg aatcatcaga gatattttca gcatgggggc tcgtccaatt
    28981 gcgttgctag attcattgag gttcggcgaa ttagataatc caagaacgaa atatttacta
    29041 gaagaagtag ttgcaggtat cggcggatac ggcaattgta tcggcatacc gactgtaggc
    29101 ggcgaaattg catttgatcc ttgttatgaa ggaaacccat tagtcaatgc aatgtgcgta
    29161 ggtttgattg aacacaaaca tatccagaaa gggcaagccg ctggcgtcgg taattcgatc
    29221 atgtatgtag gtgcaaaaac aggtcgcgac ggtatccacg gagcaacttt tgcctcagaa
    29281 gaatttaatc aagaagaaga acagcaacgt tctgctgtac aagtaggcga tccttttatg
    29341 gaaaagctgc tgcttgaagc gtgtttggaa ttaatcttgc atcattcgga ttctctaata
    29401 ggtatacagg atatgggagc agcaggactt gtttcatcta gtgcggaaat ggcttcaaaa
    29461 gctggctcag gacttatatt gacattagat gaagtcccac aaagagaaac tgggatgaca
    29521 ccttatgaaa tgatgttatc ggaatcacaa gaacggatgt tgatttgtgt taaatcagga
    29581 gaggaagaaa aaatccaaga actatttcag aagtatgatc tagatgcagt cactatcggt
    29641 aaagtaacag acgacgggca atatcggcta tatcatcaag gagaagaagt agcaaatctg
    29701 ccagtcgatg cattagctga agatgcacca gtttatcata aagaaatgaa agaaccagct
    29761 cgaatcgtag aatttcagca gttagctcct tatcagccag ttatcgaaga acctggacaa
    29821 gtattgcttg atctgctgca gcaaccgacg attgcttcaa aacgttcaat ctacgaaact
    29881 tatgattcac aagtacaaac caatacagtt gtccgtccag gaagcgatgc tgctgtgatg
    29941 agggttagag ggacgaataa agcgttagct atgaccacag actgcaacgc gcgctatctg
    30001 tatttggatc caaaaatcgg aggacaaata gcagtggcag aagctgctag aaatattatt
    30061 gctagcggtg gtaagccctt ggcgatcacc gactgcctga actatggttc tcctgataaa
    30121 ccagaagttt tttgggaatt atcgacttca gctgacggaa ttgctgctgc gtgtgaaacg
    30181 ttaggaactc ctgttatttc aggaaatgtc tctttatata atgaaacgga tggtcaagca
    30241 atctatccaa caccaatgat tggtatggtc ggattgattg aggatcataa acatatcact
    30301 actcaggaat tcaaaaaatc aggggatcta atctatatat taggtaagac gtttgcagat
    30361 tttgatggca gtgaattaca aaagatgcag cttggaagaa tcgaaggtgt gatccgaaac
    30421 tttgatctat ccattgaaaa gagaaaccaa gagttagtat tgacagccat ccaaaacgga
    30481 ttgattgaaa gtgctcatga ctgttcagaa ggtggcttgg caattgcact ggcagaatca
    30541 gctttcaaac atcagctagg gatatctgta cagtttgaat tgtcctctgc tcaattattt
    30601 gcagaaactc aatcaagatt tgtgttgaca gtcgcaccgg aaaataagac acgattcgaa
    30661 gaaatgatgg gagatgctgc tgttttagca ggtaaggtga cggatgaagc gataatcgaa
    30721 atttcagcaa ctgacggtca gatcaaaata gaaactgcag tagcaagaaa gtgctgggag
    30781 gatgcaatcg tatgtcttat gaagtgaaga gtttaaatga agaatgcggg atcttcggtg
    30841 tttggggtca tccagacgcc gctagtgtgg catacttcgg gctccatagt cttcagcatc
    30901 gaggacaaga aggtgcaggt atcgtgtcca atgatcgagg aaagcttaag gggcatcgag
    30961 atttggggct gctttctgag gtattcaaag atcaaagaaa attgcagcag ttaacaggag
    31021 aagctgcaat cggacatgta cgttatgcaa cagcaggcaa tggaagtgtg gacaatattc
    31081 agccttttct attcaaattt catgatcagt cgatcggctt agcgcataat ggtaacttga
    31141 tcaatgctcg ttcccttaga aaagagttag aggaaaatgg ggcgatcttc cattctaact
    31201 ccgatacgga gatattgatg catttgatcc gacgaagtga agaaacagat tttttaaata
    31261 aattaaaaag tgctttgaat gaagtcaaag gtggctttgc ctatttatta atgacagaaa
    31321 cggcaatgat tgccgctttg gacccaaatg gttttcgtcc attagcaatc ggacaaatga
    31381 aaaacggagc atacgtgatt gcctcggaaa cttgtgcatt agaagttatt ggggcacgtt
    31441 ttataagaga tgtccagcct ggtgagatag tgatcatcaa tgacgaagga atccagattg
    31501 attgctttac gaaggacacg cagctttcta tttgttcgat ggaatatatc tattttgcca
    31561 gaccagattc aaacatcgca gggatcaatg tgcatactgc acggaaaaat atgggacgga
    31621 atttagcgaa agaatcgcca gtaaaagcag atatggtcgt tggcgtacct aattcttctt
    31681 tgtcagccgc aagcggttat gcggaagcta gtggaatccc ttatgaaatc ggattagtaa
    31741 aaaatcaata cattgcccga acatttatcc agccaacgcc tgagctaaga gagcaaggtg
    31801 ttcgaatgaa attatctgct gtacgaggag tagtggaagg taaaaaggtg attatggtcg
    31861 atgattcaat tgttcggggt acgacaagca gacggatcgt ccatcttttg aaagaagcag
    31921 gggcaaaaga agtccatgtg aggattgctt ctcctccttt gaaatatcca tgtttttacg
    31981 ggattgatat tcaaacgcgt aaagaactca ttgcggcaaa tcacacgatt gatgaaatca
    32041 aagaatgtat cggtgcagat tctttaggtt ttttaagtga agagggtctg atcgaatcga
    32101 tcggtctgga aaaagatgct ccgtattcag gattgtgtat ggcttatttc aacggagatt
    32161 atccgacgcc gttatatgac tatgaagaaa aatatcagga atcactaaaa gaaaaagtat
    32221 cgttctttta aaagcagacc aagaagggag tatatgaatt caatggcaaa tgcatacgca
    32281 aaagctggcg tagatgtcga agctggatat gaagtagtag aacggatcaa gaagcatgtc
    32341 aaaaaaacgg aacgtttagg tatgatgggc gctataggag gattcggcgg ttgttttgat
    32401 ttatcggtct ttcaattaaa agagccagtc cttgtctcgg ggaccgatgg cgtggggacg
    32461 aaattagcag tggcaatcga agcagacaaa cacgatacaa tcgggatcga ctgcgtagcg
    32521 atgtgtgtca atgatatctt agcacaaggc gcagagccgt tatatttctt agactactta
    32581 gcaacgggga aaaatgatcc gttacgtttg gaaaatgtag taaaaggtgt agcagatgga
    32641 tgtgttcaag gaaatatggc gctgattggc ggagaaacag ctgaaatgcc tggtatgtac
    32701 tcaggtaatg attatgatct agccggattt gctgtaggga tagctgaaaa atctcaatta
    32761 ttgacaggag aaacgatcaa cccaggagat gtgttgcttg gaatagcatc tagcgggatt
    32821 cattcaaatg ggtactctct tgttcgcaaa attttctttg agcagcagca gttttcttta
    32881 tcatcaaaac tgccagaatt gaaaaaaaca cttggcgaag aattgcttga gccaacgaaa
    32941 atctatgttt cttccttgct tccgctgatc aaagaaaaga aaataaaagg agctgcacat
    33001 atcactggtg gagggtttgt agaaaatatc ccgcgaatgt taccagaatc tatggctgca
    33061 caaatcaaac ttggctcatg gccgattctt ccaatattcg gctgtttaca aaaatatggt
    33121 gaaattcctg agatggagat gtatgaaatc ttcaatatgg gcatcggtat ggtcctggca
    33181 gtccaagaat cgaaagtaaa agaaatagta cacgaaattg agcaagctgg cgaaaaagtt
    33241 tatgaaatcg ggaaagtgat cgccaaagaa aaacatcgtg tggtgtttat aggagaagaa
    33301 cgatgagaat cgctgttttt gcttctggaa acggaagcaa ctttcaagcg ctagccgatt
    33361 atctatcgaa aaaaggattg gaatcttcga ttgactggtt gttttgtgat cagcctgaag
    33421 catatgtttt gaaacgtgca actgcgttga gtgtaccggc agattgtttt tcacctaaag
    33481 aatttgattc aaaaaaagag tatgaagaag caattttgca taaattgaaa gaaaaaaaga
    33541 tcgatttgat cgtattagct ggatatatgc gaatcattgg accggtattg ctgaaaaatt
    33601 atgataaaag aatcatcaat atccatccgt ctcttttacc tgccttccct ggtttgcatg
    33661 gcatacgtga tgcctttgaa gctggagtaa aagaaacggg tgtcacaatt cattatatcg
    33721 accaaggtgt agatactgga ccaatcatcc ggcaggaaaa agtgagaatt gaacaggagg
    33781 acacgttcga ttctttagaa gaaaaaatcc atagagtaga gcatcgaatc tatccagaag
    33841 tgattagtga aattattgaa aatggaggct atctgaaatg acaagagcat tgatcagtgt
    33901 atcagataaa actgggattg tagcattcgc ccaaggtttg attgaacaag gagtagaaat
    33961 catttcaaca ggaggaacaa agcatgcgtt ggataaagct gggatcaaaa cgctttcgat
    34021 cgaagaagtg acagggtttc ctgaaatgat ggatggccgt gtcaaaacac ttcatcctaa
    34081 aatccatggt ggtcttttag gaagacgcga tctccctagc catatggagg caatggaaac
    34141 ggaaaatatc caaccaatcg actttgtttg tgtcaattta tatcctttca aagaaacgat
    34201 tatgaaacca gatgtcgaaa tagcagaagc tattgaaaac attgatatcg gtggtcctag
    34261 tatgctccgt agtgcagcaa aaaaccatga atttgtcacc tctgttgttg atccatctga
    34321 ctatgaagaa gtactttcag aattacgtca gtatgggcat acttcacttt ctttcagaca
    34381 aaaactagcg gcaaaagtct ttcgtcatac tgcggcatat gatgcactga tcgctcaata
    34441 cttaacggat tgggtggaag aaaaagaacc ggaaaaattg acacttacgt atgaacgaaa
    34501 acaaacgctt cgttacggtg aaaatagcca tcaagccgct gccttttatc agtccgctct
    34561 tctggaaaaa tattcgatcg cagcagcaaa acaactccat gggaaagaac tttcttataa
    34621 taatatccga gatgcagatg ctgcgctacg gatcatgaag gaatatgacg agccaacggt
    34681 agtcgccttg aaacacatga atccttgtgg tattgggaca gcatctacga ttttagaagc
    34741 gtgggaagca gcgtatgaag cagatcctgt ttcaatcttt ggtgggatca tcgttttgaa
    34801 tcgagaagta gatctgccaa cagcagaaca gatgcataag ctgtttctag aaatcatcat
    34861 tgccccttct tatacacaag aagctttgga attactgcaa aaaaagaaaa acatccgatt
    34921 actgacagta gactttgcgc aggaagaaaa tcaaaatcga gaagaaacgg tctcagtctt
    34981 aggtggactt cttgtacaag atcaagatct ggcaatagaa aatgaagaag agtggaaagt
    35041 cgtgacaaaa cgtaagccga ctccagcaga agcaaaagca ttagcgtttg cttggagagc
    35101 tgtcaaacat gtgaaatcta atgcgatcgt actggcaaac gaacgtcaga cagtaggaat
    35161 cggagccggg cagatgaatc gagtcggttc agtaaaaatt gcgattgaac aagcgcaaga
    35221 gaaaatggaa ggtgcagttt tagctagcga tgcttatttt ccaatggatg attcggttga
    35281 atatgcagcc aaacatggta taaaagcaat cattcagcca ggaggaagca tcaaagacca
    35341 agattctatt gatatggcga ataaatacga tctagcaatg gtctttactg atgttcggca
    35401 ttttagacat tagagaggag tcggataaat gaacattttg gtgatcggtg caggtggtcg
    35461 tgaacatgca ataagtaaaa aacttttagc cagtccgaag gtggatacgg tgtattgtgc
    35521 gccaggaaat ccggggatga caaaagatgg tatcaattgt gtcgctatca gtgagcgaga
    35581 tcattcagcg ttaatccatt ttgttaagaa agaggctatt gattggagta tcgttggtcc
    35641 tgaagttcct ttgttaaatg ggatcgtcga tgattttatg gcggaaggat tgaaaatctt
    35701 cggtccgaca aaagcagcag ctctgatcga aggttcgaaa agttttgcta aacaattaat
    35761 ggatacttat caaatcccga cagctaaatc cagaagtttt gaatgttacg aaaaagcagc
    35821 agcgtatatc aaagaaaatg gtgcgccaat cgtagtgaaa gcggacggct tagcagctgg
    35881 gaaaggtgta gtcgtggcta ccacagtgaa ggaagcgctg gatgcggcag aacaaatgtt
    35941 gaaccagcat cgatttgggg atagtagcaa aaaaatcgtc gtagaagagt ttttggcagg
    36001 agaagaattc tcccttttgg cgtttgtccg taataccaag gtgtatccga tggtcatttc
    36061 gcaagatcat aagcgggcat ttgataacga taaagggcca aatacaggcg gaatgggtgc
    36121 ttattcacca gtaccgcaaa tttcaaaaaa gatgattgaa aaagctgtgg aagaagtttt
    36181 aaaaccagcg gctttgggaa tgaaagaact aggacgctct ttcacgggtg ttttatatgc
    36241 gggtttgatt gctacgaagg aaggaccaaa agtgatcgaa ttcaatgcgc gtttcggtga
    36301 tcctgaaacg caagtcgttc tttctcggtt gaagagtgac tttgcgcaag taatcgatga
    36361 tttattagag aatcgtacag tagagttaaa gtggcagcaa gaaggataca atgtaggcgt
    36421 tgtggttgca gctgccggtt accccgaaga atatgagaca ggaatggttc taccagattt
    36481 tctggaagaa gagctttctg tttactatgc tggagtttcc tcaaataacg gcaaactagt
    36541 tggagcagga ggacgtcttt atttagtaga agcatacggt gagacgatca aagaagcaca
    36601 gaaaaaaatt tacaccgcgt taatggataa aacgacagat ggaacatttt atcgtacaga
    36661 tattggagaa aaagctgcca atagcgaact gatcgtgaag taaatcagct gcttccattt
    36721 ataaaaaata caacaaacat aatcggaagc gccgatttta gtgaagcctt ttcataaaga
    36781 gtgtggtaca cttttgttgt gtatataaat aaggaggagt tcagatgaaa aaaattcaat
    36841 taggtacttc tgatcagaaa gcagctgcag tgatcttagg ctgtatgcgt atcaacaatg
    36901 cggaagatcc agtaaaagtg attgagacag cttatgaaaa cggcattgat ttttttgacc
    36961 atgcagatat ttatggaaac ggtgaatgtg aagaaatctt tgcagatgct ctagcaaaaa
    37021 catcaatcaa acgagaagat ctttttattc aaacaaaatg tggaatcgtt ccaggtgtga
    37081 tgtttgattt ttctaaaaaa catatcattg aatctgtaga aaaaagtttg acccgtctga
    37141 aaatggatta tgtggatgct ttacttcttc atcgtccaga tacattggta gaaccagagg
    37201 aagtagctga agcgtttgat gaattggaac ggtcaggaaa agttcgttat tttggcgtca
    37261 gcaatcaaaa accaatgcaa atcgaattgc tgaaaaaata tgttcgtcaa ccattagtag
    37321 ctaatcagct gcaatttggc ttgaaacata ctggaatgat cgatcaaggg attcatgtca
    37381 atatgacaga tgaagcaagt atcgatcatg acggtagtgt acttgattat tcccgattgc
    37441 atgatatgac gatccaagca tggtcaccat accagtatgg attttttgaa ggtgtattta
    37501 tcgggaacga aaaattccct gaattaaacc aaacattaga agaactagca gctaaatatc
    37561 aaacgacacc aactggcttg gcttctgctt ggattttacg ccatccagcc aatatgcaag
    37621 tgatcgccgg tacgatgaac gtagggcgaa tcaaggaaat cgctcaagct tcagaaatta
    37681 atatgtctcg ggaagattgg tacgaattgt accgtgctgc tggaaacatt ttaccttaaa
    37741 gattgtcata agcaggtcaa aagggctata aattaaaaag acagaataac ttgaaagctg
    37801 ttttcagctt cgagatattc tgtctttttt tattgcaaat ggaaagagta tcattgtacg
    37861 gatttcgttt attagttatt tttgttttta aggaaaagct gtgtccgata ttcttttgga
    37921 gaaatccctt gttttttctt aaataaataa ctgaaatagt tagggtcatt ataaccaatt
    37981 tcaaaagcaa tatctgaaat acgatagtct gattgctgca ataatttttt tgctaattcg
    38041 attctttgtt ctgtcagata atcgatgaat gtttggttaa acgattgaga aaaaatcgta
    38101 ctgaaatgag agggacttaa tgcaacttgt tgagcgaccc aagttaagga catatctgga
    38161 tcggtaaaat tttctttgat aaaatccaat gcatggttca aaattggctg atatttgttc
    38221 cttgaaggct gtgagggcag agcagttaag aaagaaatga acatataaac tgtcgaacgg
    38281 taaagcgagt cgtcggcgct gattgctaag cgttgactgg tggatgtgca atgaaccatt
    38341 tcttgcggga ttttcttttc tttcaggcag acatgctgga gtagcttagt caagacaaat
    38401 aaacgatata atcgtgttcg agttggtgtg ccttgtggtt tcgtcaagtg ttcgatgtac
    38461 ttagatactt cgtttttcga taatgaagac aaatcaagtg agaggtcaaa gtaaaagaca
    38521 gaatcaactg gaagtttcgc ttcttgaatc aaatcctcat agctgataat ttgttcttta
    38581 agggaactgg cggtttcaag tatcatctgc gtgatctcaa aagatgcagg taattcgctg
    38641 attctttctg cgacaggacc aatggcgaca gaaaaattat ttttttgtcc cttttctaat
    38701 tcatggacca acgtttgggc tacctgataa ctggtctcga tcacattttc ttcaagagaa
    38761 tcaactatta aaaatttgat gaatcgagag gaaacagcag agaagatcac ttgttgattc
    38821 tccctaaata aaaacttcaa ataatcactg agatgagcgt aatcttcaaa gtctgtactg
    38881 acttggtttg ctgctaataa tacggtcatt tttttccctg ctaaagagcg attgaaagat
    38941 tcagcaagtt tcaatgtttc actgatcgta agtgagcctt tgaacaaacc gttcaagaaa
    39001 tgattttttt tcaattcgaa aacaagatca gaagaagtgt gcgtttcttt ttgctgcaaa
    39061 tctaaagcag ttactgcttt ttctattgct tgtttcaatt cgctactttt aatcggttta
    39121 agcagataat catctgcctg tacctggatt gctcctttca tataatcgaa atcgtcgaat
    39181 ccactaataa atatgagacg agtccaagga agtagtttcc ttgcttcttt tgaaaaagtc
    39241 aacccgtcca tgaaaggcat ttggatatca gtcagaatga tgtcgggctg taagtcgata
    39301 attgaagaca gtgccatctc accatctcca gcttcgccga cataagtgat tggataataa
    39361 gaaccaagga cagttatttg ttcccgcaag ttattgcgaa tgaggtattc gtcttcgatg
    39421 ataaaaactt tatacatgtt tgtttcctcc aattgttttg ggagatagag ggatcatcag
    39481 tgtgacagtt gttccttctc ggtatttgct gtcaatcgtg ataggttttt gatcatttcc
    39541 gtaataaaga aggagacgct tgtttacgtt gtaaagtccg tagccgatac tgaaatctga
    39601 atcgatccct ttggctaact ctttacgtat ttctgccagt ttttctgcag ggatgccaat
    39661 cccgttgtct ataactttga attggatcat ctcatcaatt ttgcatgtgg taatacgaat
    39721 aaatcctttg tgacggacgt acttcgttcc atggtataca gcattttcaa tcaatggctg
    39781 caagatcatt tttaaaatag aaacaggaaa aagtgtttct ggtatatcga tcttatagtc
    39841 aagcatatgg ccgtatctta tttttaagat gactagataa tcattgatat ggctaatttc
    39901 tttttcaaga ggaatccagt cttgtccttt gcttaaagac gtacgaaaaa agccggaaag
    39961 tgcatgggtc atagtcagag cttcttcaaa gcagtcttgt tcgatcaaag aaataatggc
    40021 atccaaactg ttataaataa aatggggagt aatctgagct tgcaatacac gaacttcact
    40081 ttgtgctaaa tggtattgtt tcaaagcgtt ctcccgtaaa gactggttta gatcttccgc
    40141 cattttattc atgctagcgg taagtgtttg taattccagt gtttccggca gggttaaacg
    40201 aaagccaagg ttccctgaag aaagttgttc tgacatctcg atcagctgat tgatcggttc
    40261 ttggaccttt ctctctaaaa agcgacgatt ctttttcgca tagaaaaaaa tggtactaag
    40321 aactccaagt tccactattg ttaatagaat gagcgagcgg acaagtgtcg tatttttttt
    40381 gcttgctaag tcgatctcca cacgaacaaa atcttgtaag atatctgaca gcagttgagt
    40441 gacagaatct acctgattga tgatctcttc attggtatcc ataaaatctt ttgccaagat
    40501 attattgatc agctcgtttt gataatcttc cagtgtatcg atcgtacgta gcgatacatc
    40561 taacgtacta atttctttaa gtgtatttgt attatttttg atctctcgaa tatcattcct
    40621 aagttcttct aggatatttt cctcattgaa ctcatctacg gttacttggc cagaaatcaa
    40681 gtcccacata ctttccaaaa ctttttgatc aaccttcaaa gcaattgcat ctgctttttg
    40741 gatatttgcg atcgtctgtt gataaatcaa aagctgttgc gaatataaca gtatgctcag
    40801 tagcaaaggg ataacagcaa atagaagcat ggctttgttt gcttgggcaa aaatctgttt
    40861 tatgcttaaa ttttttgtca tgatacttct ccagtcaata atttctggtt gggatgttag
    40921 ctatattctg ctgggaaaag acagtctcgg aaataaaaat atctttaggt aatgtttttc
    40981 ctgtttgaat atttccaaaa taacgagtaa cggtattggc tacataccag ccgacatcag
    41041 gtttacactc gactacacaa ttgacgattc ctgagcgtag cttctcgatc atatcttctt
    41101 gtccatcaat agttacaatg atcaaatctt ctccaggttt gattgatgtt tcttttatcg
    41161 cagctaaagc accgtgagtc atttcatcac tatggctgta taatacatcg atttcggata
    41221 aatcatttgt ttctaaatat cgtttcatct ggtcttttcc tttcatccga ataaaatcac
    41281 cgacaattcg gtgaacaata gtcatcggag gtttatggtc gatggttcca tcttttttta
    41341 gggttggttt acgattgatt gattccaaaa atccttcgga gcgtagcttg gtcggtgtgg
    41401 agttctctga accagcaagt tctaggattc tgatttcctg tttctttgaa tttgtgaagt
    41461 gattgctgac aaataaaccc gcccgatttc cttctgcttt gaaactgggg ccaatgtggg
    41521 tgacgaaaag ctcgggatca ttcgtttgaa tatgtctgtc gacaagtatg acagggatcc
    41581 ctgctcgctt tgcttctttt aatacagagt cccacccgga ttcttgcaaa ggagtaaaaa
    41641 tgatcatatc cactttatag gcaatgaacg tccgtatatc ttggatttgc cgttcctgat
    41701 tcatgtagcc atttcggtag agaacttggt aatcttcttt ttcaagcgca gtgataattg
    41761 attcagtatg ctttttccgc cagctactct ccgttcctga ttgcgaaaaa ccaacgacta
    41821 gtgggtcagg tgcttccttt gtattaggtg tacaccccat catttggtaa gcgattacaa
    41881 caagggctaa aaaaaataaa acacgtttca ctttaaatca ctccatctgg atttgttagt
    41941 actatcttat cagataaaag ggaaaatcaa agtcaaaagg aatcaatcga aaaaaatcca
    42001 agaaacttaa aaaaatccaa gacaaaaaaa gtacacctaa aaaatttaaa gtaaatccca
    42061 taaaaaaatc aatgttaacg ctttctttat tagctatact cggtgtatca attgaaatgg
    42121 gggataaaaa atgaaaaaca aatttagaaa gattgttggg actatcgcta ttttgaccgc
    42181 aagcattcta ttaagtgcgt gtggcaattc aggatctgca gatgatagta cggggtatgt
    42241 aggaatcgct atgccgacca aatcagcaga aagatggatc gctgatggga acaacatggt
    42301 ctcggaatta gaaaaactgg gttataaaac agatcttcaa tatggagaag ataaagtaga
    42361 aaatcaagta gcacaaatag aaaatatgat tacaaaaggg gtagatacac ttgtgattgc
    42421 ttctatcgat ggttcggctt taactgatgt gttagctaaa gcaaaagaag cagatatcaa
    42481 ggtgatcgcc tatgatcgtt tactgatgaa ttcagaaaat gtcgattatt acgcgacttt
    42541 tgataatttt ggagtaggtg tatcgcaagc agcttatatt gaagagcact taggattgaa
    42601 agaaggaaaa ggaccattca cgattgaatt atttggtggc tcgcctgacg acaacaacgc
    42661 actaatcaat tacaacggag tgatgtctgt tttacaacca tatatggaca acggtcagtt
    42721 ggtcgtgcca tctggacaga cgagtttcag tcaaatcgct acgcttcgct gggatggttc
    42781 tacggcgcaa gcaaggatgg ataatctgtt aagcgcaaat tatactgacc aaacattgga
    42841 tgctgttttg tcgccatatg atccaataag tttaggaatc atttcgtcat taaaaggcgt
    42901 ggggtatggg agtgaaagta aacctttacc tgtgattact ggacaagatg cgacagttgc
    42961 tggcgttaaa tcgatcattg ccggggaaca aacacaaacg atctttaaag acacacgtat
    43021 cttagcaaaa aatacgattg aaatgatcaa agcaatcagt gatggagaag aggttccggt
    43081 caatgatact gaaacttatg ataatggggt gaaaactgtc cctacgtatt tagcaaatac
    43141 agtatctgtc gataaagata attatcaagc agagctgatc gacaccgatt attataaaga
    43201 atccgatctg aaaaattaag aggaaccaaa caaggaacta aagagatcta agtcagagag
    43261 aggataagaa ttatggcgga ttgtatttta aaaatggcag atatcaccaa aaaattttct
    43321 ggaatccgag cgttagattg cgtgaatctg atgattgaac gtggggaaat ccatgcattg
    43381 tgcggagaaa acggagcggg aaaatcaaca ttgatgaatg tcttgagcgg cttgtatcca
    43441 tatggctcct atgacgggga aatcttttat gatggaaagc tgtgtcaatt taaagatttg
    43501 aaagatagtg aagaaaaagg catcgtcatc attcatcaag aattagcact aagtccttat
    43561 ctttcaataa aagagaatat ttttctcgga aatgaacaag cagaaagagg cgtgattgat
    43621 tgggaactga cagaaaagaa aacatatgaa ctgctgaata aagtcggttt gtctatcgac
    43681 ccgaatcttc tagtatccca gattggcgta gggcaacagc aactagttga aatagctaaa
    43741 gcattatcaa aatccgtccg tctgttgatt ttggatgagc ctaccgctgc attgaatgaa
    43801 gaagaaagcg cgaatttgct gagattgatc cgagagttga aagagcaagg tgtaacctcc
    43861 atcattattt cacataagct gaatgaaatc gtggatatcg cagatcgaat caccatttta
    43921 cgggatggac agacgattga gacactagaa aatgaaatga tcagcgaaga gcatattatt
    43981 cgcggaatgg tgggcagaga tttagttgat cgttatcctg aaagaaaacc ggatattgga
    44041 gaagtttatt ttaaagtaga agactggacg gtctatcacc ctcttgatca cgagcgaatc
    44101 ataaacgacc acatcaactt gcatttgaaa aaaggagaga ttgtaggaat agctggactg
    44161 atgggagcgg gcagaactga attcgctatg agtctatttg gacattctta tggaagcaag
    44221 atatccggac gtatattaaa ggaaggggca gagatatcag ttaagaccgt tccttcagcc
    44281 attgcaaacg gactcgctta tgtctcggag gaccgaaaat ctttaggact gaatctgctg
    44341 atggatattc gggaaaacgt gacgctgagc agtttggata aaataagtca aaaaggagta
    44401 ttagataaag aaaaagaagt aactgaggca gaaaatttcc ggaaaaagat gcgtataaaa
    44461 acaaactcca tccatcaaat tgtcagtagt cttagtggtg ggaatcaaca aaaagtcgtt
    44521 ttatccaagt ggctgatgac acaacccgat attctttttt tggatgagcc aacccgtggg
    44581 atagatgttg gggcaaaata tgagatctac acgattatcg aagaaatggc agcaaatggc
    44641 aaagctgtct gtcttatctc ttctgaactt cctgaaatat tagggatgtg tgatcgaatc
    44701 tatacgatga acgaaggacg tattacagga gaagtctcgc gagaagatgc agatcaggaa
    44761 gtcttgatga aattaatgac gaaagaagag gtgggttaag ttggaacagg caaaaaatct
    44821 tacggataaa aaagagaaaa aactaaattt gaaaagtaga gcagctgatc tttttggtcg
    44881 ctacagcatg gtgatcattt tagcgggact acttattgcg tttcaattga tgacggatgg
    44941 tattttctgg cgtccattga atataactaa ccttgttctg caaaatagcc atatattagt
    45001 actagctgca gggatgttat tagttgtgct cttaggtcat gtggatttgt cggtagggtc
    45061 agtgatggcg tttgttggtg caattgcggg catgatgatg gtcaatcgcc aaatgaaccc
    45121 gtggatgaca gttatcgcat gtcttgcagt aggcgggctg atcggcgcat ggcaaggttt
    45181 ttgggtagct tatgcaggga taccggcgtt tatcgtgact ttagcaggat tgctgatgtt
    45241 tcgtggactg acacaagttg ttctaggagg ccaatctcta gcaccttttc cagctgtttt
    45301 ccaaaaaatg tctacgggtt atttaccaga cttaagcgaa ggaagcagcc ttcacttctt
    45361 gacattgatt ttaggaatga tcatcacgat cgtgttagtt gttggtcaat ggcgaacaag
    45421 aaatcgtcgg aaaaatcatt tatttgaagt ggaatctcca acagctttct tggtaaaggc
    45481 ggtatttaca gcagtcgttg tactaggaat aacttatatc tttgcctctt atcaagggta
    45541 tccgattatt ttgatcattc ttggtttgat cgttgcagca tatgggtttt tgacaaataa
    45601 aacagtagca ggtcgacaga tttatgcgac gggcggaaat cgaaaagcgg ctgaactatc
    45661 agggatcaaa acaaagcgaa tcacgttctg ggtattcgtc aacatgggag tcatggcagc
    45721 tttagctgga ttagttttag ctgctcgatt gaatgcggca acacctcaag caggtacatc
    45781 gatggaactg gatgcaatgg cggcagtata ttttggtggt gcttcgactt ccggcggcat
    45841 tggaacaatc atgggtgcga ttgtcggtgg cttggtcatg ggtgtattga acaatggcat
    45901 gtcgatttta ggcgtcgggg tagactggca gcaggcaatc aaaggattga tcttgctttt
    45961 agccgttgtg ctagacttgt ataataagaa aaaacgaaca acgtaggaga acgccggtta
    46021 ttcagaaaaa agactgtgac aagacatttg tcacagtctt tttttcgcta aaagcgaaca
    46081 ttcattgttt cgtttgtata gactaaaaat aatatatgtt tttttaccat tcgtataaat
    46141 tctctttttg ctcttgattt ttttgcttaa ttgagttaaa ttacataggg cgctaaaaaa
    46201 agccttgatt aaattaataa tgttcgtgtt ttgctggatg tgaacatcag gaggataatg
    46261 taatgaaagt atttgattac gaagatattc aattaattcc taataaatgt atcgtaaata
    46321 gccgttctga atgtgataca acggtcacat taggtaaaca tacattcaaa atgccagtag
    46381 tgcctgccaa catgcagacg attattgatg aaacaatcgc agaattctta gcggaaaatg
    46441 gttatttcta tatcatgcat cggtttgatg aagcagctcg aattccgttt atcaaaaaaa
    46501 tgaaaaagcg tggattgatt acctcgatca gtgttggcgt caagaaagag gaatattcct
    46561 ttatagagaa gttggcagaa gaatcgctaa atcctgatta tatcactatc gacatcgcgc
    46621 atggacatgc taactcagtt attgatatga ttcagcatat taaaaaatat ttgcctgaaa
    46681 cttttgtgat tgccggtaat gttggtacac cggaagccgt ccgtgaattg gaaaatgcgg
    46741 gcgcagatgc aacaaaagtc gggattggtc caggaaaagt atgtattaca aaaatcaaga
    46801 caggctttgg gactggaggc tggcaactgg cagctcttag atggtgtgcg aaagcagctc
    46861 gcaagccgat catcgctgac ggtgggatca gaacacatgg cgatattgca aaatctgtcc
    46921 gttttggtgc gacaatggtc atgattggtt cattgtttgc cggtcacgag gaatctcctg
    46981 gcgaaacaaa agtcgaaaat ggaatcgtgt ataaagaata ctttggttct gcttcagaat
    47041 tccaaaaagg cgaaaaacga aatgttgaag gaaagaaaat ctggatccaa cacaaaggat
    47101 ctttgaaaga tacactagtg gaaatgcaac aagaccttca atcatctatt tcttatgctg
    47161 gaggaagaga tctggaagcc attcgaaaag ttgactatgt catcgtgaaa aattcgattt
    47221 ttaatggaga cacaatctaa aaaataaata aaatattagg atgttgtgaa aaagttgtcc
    47281 tgcattaagt aataagaaca gccaaacaaa aatagttctt tatatgtttt gtttggctgg
    47341 aattattatc gcagatacaa gcttttgaac atcattattc agaataaggg actgtgataa
    47401 gatttttgtc acagtccctt atgttttgca aaaaaagttt ttcttttttc tcgtaaattc
    47461 ggtaaaatca aaagaaaaaa tagacaatag aaaagagaag cttatgtggg aaaaagtaga
    47521 gaaaaaacaa ggaccgattt atcgtcaaat tatggaacag attatgagag aaatcgaaaa
    47581 cggaaggatc aatcctggaa gtcaacttga atcagaacga aaactagggc aactttttgg
    47641 tgtgaatcgt tccaccgttg tccatgcatt ggaagagctt agggagcttg gggtactaac
    47701 gagcaaacgt ggcagcggat ggtttgttaa tcagactgaa tgggggaaat tcgctgttcc
    47761 aagaatcgat tggcggcaaa tgatctctcc tcgttatgag cagacggact ggtatgagca
    47821 aaaaataaga gaagcaaagc agatccaaaa aacatcgttt cttgatttat acgctagcga
    47881 gatgccagat gagcttttgc cgaattttga gtttccttct tattctcttg aagaaatctt
    47941 agcggaagaa aaagaaatgg atcttttagg ctatactccg ttacgtaaca aaatcaaacg
    48001 gtatttggaa agtaaatttg aattggcatt ttcccccaac cagcttcttg tgactggtgg
    48061 cggtcagcaa gcaatctttt tgattttaca aacgattctt tcagctggag aggggatagc
    48121 tgtagagtca ccttcttttt tttaccgatt acctcttttc aaagcttcag gaacgcgttt
    48181 atttgggata ccgatggatg aagaagggat cgacttagaa aaactgaaag aatcgatcca
    48241 taaaaataaa ttgaaagcag tgcttatcaa cccgaatttt caaaacccta caggaaaagt
    48301 gatgagtcaa aaacgacgag aaaagctagt agaattgtgt cgacagtatc ggcttccaat
    48361 tattgaagac gatgtattta cggatctttc atttctaaac caagaagaag tccttcctat
    48421 acgaacgatt gatccggata atgtgttata cgtcggttcg ttatctaggg ttttaggaaa
    48481 aacaacgaaa atcggttggg tgataggacc tgagactttt atctcgcaac tagctcaagc
    48541 gcaagaaatg atggagtttt cgatgaatat ccttacacaa atcacagtgg ctaatgtatt
    48601 taatgaagca attgatttga aaatgcaaga tgtaagaaaa aagttgaaag aaaaaagccg
    48661 actgataagc gcttggggag attcacaatc gtttttcaag cttcattcaa ttttaggtgg
    48721 ttactatgcc tggattactt gggatgggaa aaaactagac cccgaactag cagaaaaagt
    48781 agtagatatg ggtcttggaa ttgcaccaag tctacttttt gggcaagata taaatggaat
    48841 cagaatcaat tacagtaggc tggatgaaaa ccaaataccg ttgttttatt caaagatgaa
    48901 aattctagaa aagtggttaa cagaataatt tcacaaagta aatagattaa agaatataac
    48961 agcttggatt taaatttcaa gctgtttctt ttttttcgga aaaagaatac gatataaaga
    49021 aactaagaaa aaaccattat ttgtacgtcc gttcacgatg tgtaaataaa ataaatgttt
    49081 gcaacaaaac tgtataacac caacgttttt aaatagaaac agatggttgt aagtttgatt
    49141 agaaaataga aaaaatgcag atgaaatata aaacgctttc cttattgtga ttttattcac
    49201 taatgctgtt aatatgcgga ttggcataat ttcctttcat cgtgaaaatt tgtgctttta
    49261 gcttgtattt ctcataaatc catgataatt tattaatgaa gacggttaaa tagtgataca
    49321 gttttattca ctgtttcaat cgcagaatga agagattttc ttatagatga gagaggaatg
    49381 tgtgacaaat ggcaaacaaa aaagcaccga tcgacttcca agcactgcta gatgaagtca
    49441 atgcagattt cccagtatat caagcacttg atcaagatgg aaacgtagtt aacaaagatt
    49501 tagtacctga tttatccgat gatgaactcg ttgaattaat gactcatatg gtatggtctc
    49561 gtgtattaga ccaacgttca acagcgctga accgccaagg acgcctaggc ttttttgcac
    49621 caactgctgg acaagaggca agtcagctgg ctagtgctta cgcatttgat aaagaagatg
    49681 ttcttcttcc aggttatcgg gatgtacctc aactagtaaa acatggttta cctttatctc
    49741 aagctttttt atggtctcga ggacatgctg caggtaattc ttatccggaa gaattgaaag
    49801 ctctaccacc acaaattatc atcggtgcac aatatgtaca agcagccggt gttgcattag
    49861 gtttgaagaa acgaaacaag aaaaatgtcg tcttcactta tactggtgat ggcggttcat
    49921 cacaaggtga tttttacgaa gcaatcaatt tcgctggcgc ttaccatgca aatgccgtat
    49981 tttatatcca aaacaacggg tatgcgatct ctacacctcg tgaaaaacaa actgcagcaa
    50041 aaacacttgc acaaaaagct gtcgcagctg ggattcctgg tattcaagtc gatggaatgg
    50101 atccgcttgc agtatatact gtatctaaaa tggcacggga atgggcgatc agtggaaatg
    50161 gaccagtcct aatcgaaaca ctgacttatc gttatggacc acatacacta tctggtgacg
    50221 atccaacccg ctaccgtaca aaagacacag atgacgattg gcagaaaaaa gatccattga
    50281 tccgcttccg taaatatttg acggaaaaag gactttggtc tgaagaaaaa gaagaacaag
    50341 tcatcgaagc aactaaagaa gaaatcaaag cagctattgc tgaagccgac aaagtaccaa
    50401 aacaaaaggt ttcagatttc ttgaaaaaca tgttcgaagt atctccacaa tcaatcaaag
    50461 aacaaattgc aatttatgaa gcgaaggagt cgaaataatc atggcacaaa aaacaatgat
    50521 ccaagcaatc acagatgcct tagcacttga actagaaaat gacgagaatg tcgttgtttt
    50581 tggtgaagat gttgggaaaa acggaggagt tttccgggca actgaaggat tgcaggaaaa
    50641 gttcggagaa gaccgagtat tcgatactcc tttagctgaa tctggaatcg caggattgag
    50701 tttcggtctt gcgttagaag gatttcgtcc agttcctgaa atccaattct ttggttttat
    50761 tttcgaagca atggacgaag tagtagctca aatggctcgt acaagatatc gaatgagcgg
    50821 cactagaaat ctacccatca caattcgttc gccatttggt ggcggtgttc atacaccaga
    50881 attgcattcg gataatttag aaggtttgat cgctcagtct cctggtattc gagtagtgat
    50941 tccttccaac ccttatgatg caaaaggact attgatttct tctattagaa gtaacgatcc
    51001 ggttgttttc ctagaacaca tgaaactata tcgctcattc cgagaagaag tgccggatga
    51061 agcttacgaa gttcctttgg ataaagcagc agttactcgt gagggaacag atgtatctat
    51121 tatcacatac ggagcaatgg tgcgtgaagc aatcaaagca gcagacaatc ttgcaaaaga
    51181 aaatatatct gttgaaatca ttgatcttcg tacagttgcg ccattagatg tagaaacgat
    51241 cattcaatcc gtggaaaaaa ctggtcgcgt agttgttgtc caagaagcac aacgacaagc
    51301 gggcgttgcc gcgcaagtag tttctgagat ctcagaacgc gctatccttt cattagaagc
    51361 cccaatcgga cgagtttctg cacctgatac agtcttccca tttggacaag cagaaaatgt
    51421 ctggttgcca aatgcaaaag atatcgaaga caaagtaaaa gaaatcgcgg aattttaaga
    51481 aaagaaggga cgaaacaaag tcatggctta tcaatttaaa ttgccggata tcggtgaagg
    51541 aatcgcagaa ggtgaaatcg tcaaatggtt cgtcaaacca ggagatacga tcaatgaaga
    51601 tgatacatta ctagaagttc aaaatgacaa atcagtagaa gaaatcccgt cacctgttac
    51661 aggaacggtt aaaaatgtga ttgttccaga aggtaccgta gcaaatgttg gggatgtatt
    51721 agtagaaatc gatgcaccag gacacgaaga caatgaaggg gacagtggtg tagccgcaga
    51781 atcccaaact ccagctaaac cggctgctga acccactgtt gatacagaat cagctggatc
    51841 gtcaagcgaa ggagtcttcc aatttaagtt accggatatc ggtgaaggaa tcgcagaagg
    51901 tgaaatcgtc aaatggttcg tcaaaccagg agatacgatc aatgaagatg atacattact
    51961 agaagttcaa aatgacaaat cagtagaaga aattccgtca cctgtcacag ggacagttaa
    52021 aaacgtgatt gttccagaag gcactgtagc aaatgttggg gatgtattag tagaaatcga
    52081 tgctcctgga cacaatagtg caccgtcaac tagtgcgcca tcagctgaag caccaaaaga
    52141 aaaagtggaa acatcaggtt cagcaagtgt cgttgaagct gccgatccaa ataaacgtgt
    52201 attggctatg ccatctgttc gtcaatttgc ccgtgaaaaa gatgtagata tctcacaagt
    52261 aactgcaact ggaaaaggtg gcagagtaac aaaagaggac atcgaaaact tcttggcagg
    52321 tggtccaagc agtgcaccag cgaaatcaga agcgccagaa gcggcagcac cgaaagaagc
    52381 agctcctgca gcagaaagca aaccagctgc accagcaaaa ccattcaagt ccaacttagg
    52441 agacttggaa gaacgtgtag caatgacgcc aacacgtaaa gctatcgcta aagcaatggt
    52501 caacagtaag catacagctc cacacgtgac attgcatgat gaagtagaag tgtctaaact
    52561 atgggataat cggaaacgat ttaaagaagt tgctgctgca aatggtacga aacttacttt
    52621 cttgccatat gtcgtgaaag ctttaacagc gactgttaag aaatacccag tattgaatgc
    52681 atctatcgac gatgcaaacc aagaaatcgt ttataaacat tactacaata tcggtattgc
    52741 aactgatacg gatcacggac tatatgtacc aaatgtgaaa gatgcagacc gcaaaggaat
    52801 gtttgctatt gcagacgaaa tcaatgagaa agcaaaatta gctcatgacg gcaaactatc
    52861 tgcagaagat atgcgcaatg gaacaattac gatcagcaat atcggatctg taggtggcgg
    52921 ttggtttaca ccagtcatca actatccaga agtagctatt ttaggtgtag gaacgattgc
    52981 acaacaacca atcgtaaatg ctgaaggcga aatcgttgtc ggtcgtgtga tgaaactgtc
    53041 attaagtttc gatcaccgta tcgtagatgg agcaactgcg caacaagcaa tgaataatat
    53101 caaacgtctt ttagctgatc cagagctatt aatgatggaa ggatgataaa caaatggtag
    53161 ttggagattt tgctgtagaa ttagatacag ttgtaattgg tgcgggacct ggtggctatg
    53221 tagctgccat ccgcgctgct gaaatgggac aaaaagtagc aatcattgaa agagagtata
    53281 ttggcggtgt ttgtttgaat gtcggctgta ttccttcaaa agcactgata gctgcaggac
    53341 accattatca agagtcacta gattctgaaa tgtttggagt aactagtgaa aacgtcaaac
    53401 tagattttgc aaaaacacaa gaatggaaag aaaacaaagt tgtccatacg ttgacttctg
    53461 gtgttggttt cctattaaaa aaacataagg ttgaaacaat cgaaggagaa gcgttcttcg
    53521 tagatgatca cacactacgc gtcattcatc cagattcagc tcaaacttat tcgttcaata
    53581 acgcaatcat cgcaacaggt tcccgtccaa tcgagattcc aggatttaaa ttcggaggac
    53641 gtgtgttaga ttctactggc ggattagcat tgaaagaagt acctaagaaa tttgtgatca
    53701 tcggtggcgg tgtgattggt gccgaattgg gcggagcgta cgcaaactta ggagcagaag
    53761 taacgattct tgaaggctca ccacaaattt taccaactta cgaaaaagat ctagtaaaat
    53821 tagtagaaga tgatttcaag aaaaaaggcg taacagtcgt aacgaatgca atggcgaaag
    53881 aagcagtcga taacggtgac agcgtgacag tgaaatatgc agtggacggg aaagaagaat
    53941 ccgttactgc tgattatgtg atggtcactg taggtcgtcg tccgaataca gatgatatgg
    54001 gcttagaaca agcgggtgtc gaagtaggag aacgaggatt gatcacggtg gataaacaag
    54061 gacgtacgaa cgtacctaac atctatgcca tcggtgatat cgttccaggg gcggcattag
    54121 cacacaaagc cagttatgaa gcaaaaatcg ctgctgaagc aatctctggc aaaaaagtag
    54181 ctgtagatta taaagcaatg ccggcagtag ccttcactga tcctgaattg gcttctgtag
    54241 gtatgacgat caaagaagca aaagatgctg gtatcgaagc aaaagcatat aaattcccat
    54301 tttcagggaa cggtcgggca ttatcgcttg gtaaaacaga aggattcatc cgtctagtta
    54361 cgacgatcga agataacgtg cttattggcg cgcaaatcgg tggagtcggc gcaagtgata
    54421 tggtctctga attagcttta gcaatcgaat caggaatgaa tgctgaagat atcgccttga
    54481 cgattcatcc tcatccatct cttggcgaaa tcgtcatgga tgcttcggaa ttagcattag
    54541 gtttaccaat ccatatttga tttgaataat acaggcgaaa cgcaactgaa aaatcagttg
    54601 cgttttgttt tttagaatta tcaataatat tattatgtaa acttaaaaat atgacaactt
    54661 cttggtttat taccacttcc tatgctacac tgaagaggaa tatgaaatag gagagttgaa
    54721 gatgcaagaa tatcagtatc cacttgattt agattggaca acagacgaaa tggtcattgt
    54781 aatgaagatg tgggaagatc tggaacgtgc gaatgaaaaa gggataaaca atgaagcttt
    54841 tttgaagact tatcagcagt ttaaaactgt tgtcaaatcc attggtgagg aaaaacgatt
    54901 gggacgggaa tttgaaaaag cttccggtta ttctttatat cgtacagtgc agcaagcaaa
    54961 aaaaaatcca aacaaaactt tgagaatgaa cgggtgagat aaatggaaca gatgattgat
    55021 catatcaagt cctggcttga agaagctggt gagaaaatca aatcttctca acaaacatta
    55081 acaatctcgc aaaaatcaaa tcgaacggat ctagtaacaa atgtcgatcg aaacatccag
    55141 aattttctaa tcgaaaaaat ccattccttt gatccagagg cgaaaatatt ggcagaagaa
    55201 gaagggtgta atcaattatc ggatctcgat ggaagagtct ttatcatcga tcctattgat
    55261 ggcaccttga attttgtgat tgaaggggaa aatttttgta ttatgctcgc tgtttatgaa
    55321 tccggcgttg gaaagcttgg tttcatttat gacgtgatga gaaatgaact tttttggggt
    55381 ggaaaaggaa taggcgtgta taaaaatgat gagccattgc ctagaccagc aaataaatcc
    55441 ttatcggaag gcttacttgg tgtgaatagt tatcttttcg gtcataataa atatggaatc
    55501 cgagaaattg cggaaagcag catggggaca cgtatgtacg gatgcgctgg tcttgaacta
    55561 gtggcaatct tgaaaggaaa ccacattgct tatatttcaa accttagccc ttgggattat
    55621 gcagcgggaa atgtcttatt ggaagagttt ggtatggtaa caagcggtct ttttggtact
    55681 cctttgacat ttgaaaaaag ggaatactat ttagcaggga cttcttgtgc atatgcagaa
    55741 atcgcagacc ttttgaaaaa agaaggctga aaaaaaggta gaaatcattc acaaaaatga
    55801 taaaaacgag caaaagatta attttctcga aaaaatgaaa acattttact atatttcatg
    55861 aaaaaagtct gctataatta gcagtcgagt aaaatttgcc ctgtcataaa gaaccaataa
    55921 aaaaggagtt agttacattg aattatagaa acgatatccg taacgtcgca attattgccc
    55981 acgttgacca cggaaaaaca acattagttg atgaactatt aaaacaatca gatacattag
    56041 acgcacatac gcaattgcaa gaacgtgcga tggactcaaa tgcgctagaa aaagaacgtg
    56101 gtatcacgat tttagccaaa aacacagctg tagactataa aggtattcgc gtaaacatca
    56161 tggatactcc aggacacgcg gacttcggtg gcgaagtaga acggatcatg aaaatggttg
    56221 acggcgttgt gttggtcgta gatgcgtatg aaggaacaat gcctcaaaca cgttttgtat
    56281 tgaaaaaagc actggaacaa catatcacac caatcgttgt cgtaaacaag attgacaaac
    56341 cttctgctcg tcctgagcat gtcgtagatg aagttcttga actattcatc gaattaggag
    56401 cagatgatga tcagttagac tttcctgtga tttatgcatc tgcactaaat ggtacgtcaa
    56461 gcttgtcaga tgatccagca gatcaagaac caaccatggc acctattttt gatacaatta
    56521 ttgaaaaaat ccctgctcct gtcgataaca gcgacgaacc attacaattc caagtttcat
    56581 tacttgacta caacgattat gtaggtcgta tcggaatcgg acgtgtattt agaggaacaa
    56641 tcaaagtagg agaccaagta gcattaatta aattagacgg aacagttaag aaattccgtg
    56701 taacgaaatt atttggtttc tttggactaa aacgtctaga gattcaagaa gcaaaagctg
    56761 gagacttgat tgctgtctca ggtatggaag atatctttgt cggtgaaaca gttactcctg
    56821 tggatcatca agatgcgtta cctatccttc acattgacga accaacattg caaatgactt
    56881 tcttagttaa taattcacca tttgccggtc gagaaggtaa attcgtaacc gctcgtaaga
    56941 ttgaagaacg tttgatggca gaacttcaaa cagatgtatc cttacgagtt gaaccaacaa
    57001 actctccaga tgcatggaca gtttctggtc gtggagaatt gcatttgtct atcttgattg
    57061 aaaacatgcg ccgtgaggga tacgaattgc aagtatctcg tccagaagtt attgaaaaag
    57121 aaatcgacgg tgtaaaatgc gaaccgtttg aacgcgtgca aatcgataca ccagaagaat
    57181 atatgggtag tgttatcgag tccttgagct tacgtaaagg tgaaatgcaa gatatggtcc
    57241 atacaggaaa cggacaaatc cgtttgacat tcttaacacc tgcccgcggt ttgattggtt
    57301 attcaactga attcctttca atgacacgtg gttacggaat catgaaccat acttttgacc
    57361 aatatctgcc aatgcttcct ggtcaaattg gcggacgtca ccaaggggcg cttgtttcga
    57421 tcgatacagg aaaagcaacg acttattcta tcatgagtat cgaagaacgc ggtacagtct
    57481 tcgtagaacc aggtacagaa gtatatgaag gaatgattat cggggaaaac agccgtgata
    57541 atgatttgac tgtcaacatc acgaaagcaa aacaaatgac aaacgtacgg tctgctacta
    57601 aagaccaaac atctgtcatc aaaaaaccaa aacaattgac gttggaagaa tctttggaat
    57661 tcttgaatga tgatgaatat tgcgaagtaa caccagaaag cattcgcttg agaaaacaaa
    57721 ttttagagaa aaatgctcgt gaaaaagcat ctaaaaagaa aaaataatct gtaaaaggat
    57781 gaagagagaa accagcttgt tataaaaaat agctggtttc tttttttgtc caactctttt
    57841 ctgtggagaa gtcatctttg tcaatggaca taaattcaga aaatacgccg aaagacgttt
    57901 aaaagacttt taaaaaactt atttctagag agtttttgtt tcataataag ataatgtttc
    57961 acgaaaggag atcaacttgt ccttcgaaga aaatcgaagt aaaatggcaa gagaaaggag
    58021 cgggaagatg aacgacttat taaaacaata ctttggctat gatgagttta gacctggtca
    58081 aaaagaaatt atccagaaag tcattgatca ggaaaatgta ttaggaatca tgcctaccgg
    58141 aagtgggaaa tcaatctgtt accagcttcc agctttacta ttagatgggc ttactgtggt
    58201 tgtgtcccct ttaatctctt tgatgaagga tcaggtggac gcggcgaatc aattaggtat
    58261 acccgccact tttatcaata gctcgttaga tggttacgaa acagctagac gcttccaaga
    58321 aatcgataga cagcagtacc gtttacttta tatcgctcct gaacgtttta tcatgccgga
    58381 ttttatccaa gcaatgaagc gatggaacgt ccgtatgatc gctattgacg aggcacattg
    58441 tatctctcag tgggggcatg atttccgccc aagttattta cagatggcga accagctaga
    58501 tcaactgcca aatcgtcctg taattgttgc tttgacagct acagcgactg tgcaagtagc
    58561 tgctgacata aaaagacttt taaaaattcc agaaaacaac catattcaga ctggttttga
    58621 acgagaaaat ctacgatttc aagtaattaa agatcaaaaa aaagaacaat atctaatcga
    58681 atatttaaag atcaacaaaa atcaatctgg tatcatttat gcagcaacga gaaaagaagt
    58741 agaccgtctc tatcatttgc ttaaaaaatt cgatttttcc gtgggtagat atcatggtgg
    58801 tctaaatgag aatgagcgaa cagaaatgca agaagccttt ttatacgatc gcttgcagct
    58861 gattgtagcg acaaatgcat ttggtatggg tataaataaa agcaatgtcc gttttgttat
    58921 ccattatcaa attcctggct ctctagaagc atactatcag gaagctggtc gggcgggaag
    58981 agatggtctt tccagtgaag ccatcctgct tttctctcct caagatatcc aagtccaaaa
    59041 gttttttatc cagcagtccc aaagagaaga agggcaaaag caaaaagaat atgaaaaatt
    59101 aaaagcgatg acagaatacg tgtatattga gtcctgtctt cagcaataca tcctaaacta
    59161 ttttggcgag acaagcagtc cgtgcaaccg ttgtggtaac tgtttagatg acagagaaat
    59221 agtagaagta acgacagaag cacagatggt tctttcttgc ttaaaacgta tgggtgagaa
    59281 ctatggtaaa caaatgctga tgaaagtctt agcaggatcg aaagaacaaa agctgcaagc
    59341 tttaggtttt ggacatttat ctacctatgg actgatgaaa aaccaatcgc aaaaagaaac
    59401 gatgcagtta attgaatatt tgatatcgaa tggctatctt ctgaccatca atggtgagta
    59461 tcctgttttg aaagtaacag aaagagggat acaagtattg aaaggacaag aatctgttta
    59521 tcgaaaggaa cccaagaaag tccagcagct atcggatgaa gaaaccgata cactatttga
    59581 agtgctgcgg gaactgcgaa cggatctagc atcagaagca ggcgttcccc cgtatgtcgt
    59641 attttcagat tccacattga aagaaatgag ccgaatacgt ccatcaagca gattggagat
    59701 gcttcagata aaaggagttg gccaaagcaa gcttgataaa tatggcgaag cctttttatc
    59761 tcggataaaa aatgcggact ctaacgttct ggataagtag aaagaacgaa tacgtaaaaa
    59821 tgaataaaaa caactggtta aatctgtttt ttttgctcct tatgaaaatc aaatatgtta
    59881 taattaagga attagaatgg gaggtaagca cagatggatt ctttgtcgaa aaaacttgcg
    59941 atccaagtat taaatgatga agcagaacgg atcaaacgat taatccgaaa tcaaaacaac
    60001 agtctctgta tctcacaatg caaagccttc gaagaagtgg tagatacaca gatgtacggc
    60061 ttttcccggc aagtcggttt tgctgtccgt ataggagtaa tcggaaagaa cgagggccag
    60121 ctgatgttaa gtgagctaga acgagaattg aatcagttat atagtgaggt ttaccaagaa
    60181 atttatgata aaaaagaagt tggcaaggag gaatagactt gcctaagaaa gtgaaaaaaa
    60241 ggcatctatt agactatagc atcttgattc cctatttaat tttatgtgta ttgggattga
    60301 tcatggtata tagttctacg tcgtatctat tattagaaaa cggacaaaat ccgtccgcat
    60361 cagtcattaa ccagagtatt ttttgggtgc ttagcttgat tgctatcgca ctactttata
    60421 aaatgaaaac agatgttttg aaaaaccagc gtttgatcat ggcagccatc gcagttttga
    60481 cgattttgct gctgattgtt gtgttttttg gtaaggagat caatggggcg aaaggttggc
    60541 tgcaaattgc aggattctcg atccaacctg ccgaatacct aaaaatcatt tctatctggt
    60601 acctgtctct gactttatct aaaagacaaa acagtgtaca aaaagatttt cttgggactg
    60661 tgaaacgtcc acttgcaatg gttatcggac ttactgcatt agtcgctatt cttcccgatt
    60721 ttggtaatgc ggcagttatc tttttgatta ttttggttct gcttttagcc agcggagtca
    60781 attatgtgta tactttgatt gtaggagtag gaggcttttg tctaagtact tttacgatct
    60841 ggctgatcaa tatcacaaac ggaaagatct tacccggacg tttacagtat atctataatc
    60901 gatttgctat ttaccaaaat cctttctcag acgaattaaa taaagggcat caactagtca
    60961 acggctacta tgccatgttc aacggaggac tatttggcag gggattaggt aacagtatcc
    61021 agaaaaaagg atttttacaa gaagcacaaa ccgattttat ttatgcaatc gtagtggaag
    61081 aactgggagt gattatgggg attttgatat tagcgttgct attctttatg attgtgcgca
    61141 ttgtccttgt aggtatccgt tcaaaagatc cgttcaattc gcttttgtgc attgggatcg
    61201 gcgcaatgtt tttgatccaa gtatttgtca atcttggagg aattactggc gttattcctt
    61261 tgacagggat cacgttccca tttttaagtc aaggaggctc cagtttgctg atgctttcga
    61321 tttgtgtcgg ctttgtcctc aacatcagtg cggatgaaaa acgcaagagc ttaggtttat
    61381 aataaaaaaa gatgtaggag tggttcgatg aaaaaagttt tagttgctaa caggggtgaa
    61441 atcgctgtac gtgtatttcg tgcttgtaca gaattaggaa ttaaaactgt tggaatctat
    61501 gcagaagaag atgaatattc cgtacaccgt ttcaaagcgg atgaagcata tttagtagga
    61561 caaggaaaaa aaccgattga tgcgtatcta gatattgaag ggatcatttc tatcgcgaaa
    61621 gaatgcggag ctgacgctat tcatccgggt tacggtcttt tgtcggaaaa cttgaatttt
    61681 gcgcaacggt gcgaagaaga aggcatcatt tttgttggac ccaaactgca tcatttagat
    61741 atttttggag ataaaatcaa agcaaaagct gcagctatcg aagcggggat tgcttcgatt
    61801 ccaggcacag atggaccaat cgcttctata gacgatgcct tggagtttgc gaaacaatac
    61861 ggttatccga ttatgatcaa ggcagctcta ggcggcggcg gacgcggcat gcgtgtagct
    61921 cacgatgaaa agagtgcaag agagggctac gaacgtgcga aaagcgaagc aaaagcagcc
    61981 tttggtagtg atgaagtgta tgttgaaaaa tacatcgcta atcctaagca tatcgaagta
    62041 cagattctcg gggatacgca tggaaacgtc atccatcttt ttgaaagaga ttgttctgtt
    62101 cagcgccgtc accaaaaagt agtagaagta gcgccttgtg tctctatgaa tgaacagcaa
    62161 cgtcaaaaaa tctgccaggc agctgtccaa ttgatgaaat atgtcgggta tgtcaacgca
    62221 ggtacagtag aatttcttgt tgaaggagat gatttttact ttatcgaagt caaccctcgc
    62281 gtccaagtgg aacatacgat cacagaaatg attacagata ttgatatcgt aacaacgcaa
    62341 ctgttgattg ctcaaggttt ggatctgcat aaagaaatcg gattgcctca gcaagaagga
    62401 attaaattaa atggttcagc cattcaatgc cgaatcacta cagaagaccc gttgaataac
    62461 tttttaccag acacagggaa aatcgatacg tatcgttcac ctggtggttt tggcgtacgt
    62521 ctggatgtcg gaaatgctta cgcgggctat gtagtgacac cgtattttga ttcattgcta
    62581 gtaaaagtat gtacgcatgg tgctaccttt gaaacagcca ttcagaaaat ggaacgttgc
    62641 ttgaaagaat ttagaatccg tggagtgaaa acaaacattc catttatgct caatgtcatc
    62701 acacatcctg aattccaatc aggaaatgca aaaacaacct tcattgatag tacagcaaca
    62761 ttatttgaat ttcctcgact acgagaccgc ggaaacaaaa cgatgaaata tatcggtgaa
    62821 attactgtga atggttttcc aggtatcgaa agtggcgaaa aaccatttta tgaagaacca
    62881 cgtatgccta aagatctaat cacaagaact gattacgtaa cggctaagaa tgtattagat
    62941 gcgaagggtg ccgatgcttt ggtcgaatgg atcaaaggac aggaaaattt gttgttgacg
    63001 gatacgacat ttagagacgc ccatcaaagt ctgctagcaa ctcgtgttcg gacaaaggat
    63061 ttcaagcaga ttgcacgttt gactggagaa ggtcttcctg aactcttttc aagtgagatg
    63121 tgggggggag caacatttga tgtggcttac cgctttttga atgaagatcc ttggcaacgg
    63181 ttgagaaaaa ttcgttcttt aatgcctaat acgttgctgc aaatgctttt cagaggttca
    63241 aatgccgttg ggtattctaa ttatcctgac aatgtattgg tggaatttgt caaagaagca
    63301 gcagcgcaag gaatcgatgt atttcgaatc tttgatagtt tgaactggac tccacaaatg
    63361 gaaaaaagta tccaagctgt acgggatact ggtaaaatcg cagaggcagc tatttgctat
    63421 actggcgata tcaacgatcc aagtcgggca aaatacaatg ttcagtatta taaagacatg
    63481 gcaaaggaac tagaacaact gggtgcgcat atcattgcaa tcaaagatat ggctgggctg
    63541 cttaaaccgc aggcagctta tcgtttgatt agtgaattga aagaaacgac agatctgcca
    63601 atccatctgc atactcatga taccagcggg aatggaatca tcacttattc tgctgcttca
    63661 aaagcaggag tagacatcgt tgacgtggca atgagtgcaa tgagtgggaa tactagtcag
    63721 cctagcatga gcagcttgta ttatgcactg gtcaatggtc cacggctgcc agaaatcacg
    63781 attgaaaatg cacagaaatt aaaccattat tgggaagatg tgcgcatgta ttacaaaccg
    63841 tttgaaaacg gcttgaatgc tcctgaaaca gaagtatata tgcatgaaat gccaggagga
    63901 cagtattcga atctacagca acaggcaaaa gctgtcggat taggtcatcg ctgggatgaa
    63961 atcaaacaaa tgtatcatac tgtcaacttg atgtttggcg atatcgttaa agtaactcca
    64021 tcatctaaag tagttggaga tatggcacta tttatggtcc aaaatgatct tacagaagaa
    64081 gatatttatg aaaaaggcga aacactaagt ttccctgaat ctgttgtgac tttcttccaa
    64141 ggagaactag ggcaacccgt tggcggattt cctaaaaaat tgcaaaagat tattcttaaa
    64201 ggcagacctg cattgaatga acgtccaggt cttttggctg aatcagtcga cttcaacgaa
    64261 gtaaaaaaag aattggcaga aaaaattggc tatgaaccaa aacaagacga agtattaagc
    64321 tatttgatgt atccgcaagt ctttttggac tatcaaaaag catataatca atttggcgat
    64381 gttacattac tggacacacc aacatttttc caaggtatac gtttgggtga aacaatcaat
    64441 gtacaaatcg aacgcggaaa aacgcttatc attcgtttag atgaaatcgg agaacccgat
    64501 atcgaaggga atcgcgtact gttcttcaat ttgaatggac aaagacgtga aatcactatc
    64561 aaagataatt cgatcatcag tacggtccaa acccgattga aagctgaacc gacaaaccga
    64621 gaacaaattg gagcaacgat gtctggttct gttttggatg tattagtgaa aaaaggcgat
    64681 aacgttaaaa aaggtgatac gttgatgatt actgaagcga tgaaaatgga aacggccatc
    64741 gaagcacgtt ttgacggaga agtcgcacat gtatatgtgt cttcaggaga cactatttcg
    64801 tctggtgacc ttttgattga agtgactgag aaataataag cgaaaggtgg ggaaacatga
    64861 aaagactggg tttgttttgg ctgattctgc tattagttat tgtggcattc tacatggaac
    64921 cagtcttgtt tccgccaaaa cttgaagtga aggaaaactc tgatcaacaa atatcaaacc
    64981 aaatgacaac gtggaaatac caggagctta aagcaactgg tttttctact tatatcggaa
    65041 aaccgatcga tcagctggaa aaggattttg gccaagccta tgatcgatta actagcggat
    65101 ttggttttga aacaagatat tatgaaaata aagctagtca tctcacattt gaagcgaaca
    65161 tccaagacag cagagtcaca actgttaaag tactgcaaac agggcctgct gatatcgcgc
    65221 cgttttattt agggatgacg atgcaagatc ttacgaaaat cactactatc tatactaatt
    65281 tcacttttga gtaccatgat acagaagttg gaatcgaact aatggaagag gatatgaatt
    65341 atcgtccgct aattgctttt gataacgaca cttttgctat tttatttttt gatcaaacaa
    65401 caaacggcct attttcagtt gtgtatttag ataaagatag tcttttgaaa ctattgccat
    65461 atcaagtgtt tggtgaaggc cttccacatt atcaagcaga taaatcggct gattgggaat
    65521 caatcaatcg cgttaaagaa cgaaaaagta cgactttatt aaatatgctt agaagagaag
    65581 acgaacttcc catatacaat caaacacttg cctttcaaaa ccacagtcag ctgctactac
    65641 atgatttttt gacaaggcct gaggaaatat tgtcagagga acgtatggct gattggcaaa
    65701 aatcgctagg cagtgctcaa acgacagtga aattctcact gacgaatgat gaattggaga
    65761 agttaatcag taaacaaaaa ttagaaaata ctagtgggct atttattcat ccggcgattg
    65821 acgctacttt ttcgttttta tattggtaca gcgatcctta caaccatgac cgtttcatgg
    65881 acccgggaac ggattctgta ggcattgctt tttctaaaga aaatatgtta gtcttattgc
    65941 aagaagaaaa cggagaaagt agtgatagca gtgatcgtta acgaagagct gtttcaactg
    66001 gaggatcaat gcctccaagt cgctgaaatg ataaaaaaga gtaaaacgat ggcttcttat
    66061 cttgaacata aacagtcaat ggaagaatct gcaaaagttt gccagttgaa agaagcgttc
    66121 ttgtctaaga aagaagcatt tgaaaatgta gcggcatatg gtgagtatgc acctgattat
    66181 cgtgaaaaaa aacgagctgt tcgaaaagca aaaagacagc ttgatatgga tgagcatgtt
    66241 gcagctttcc gatatagtga aacacagctg caaagtctgt tggatcaaat tgtccaagta
    66301 cttgccgaag aagtttctaa tgaaatcaaa gtagatgcag gtagcccgtt ttttgaaacg
    66361 aaaaaacact ttggatgcgg aggtaattgt catgcaatta gacaatagtg aatttgaaat
    66421 aacaaaacga cgcgggctga tcgtatgggt ctacagctta aaacaattaa agaatctgaa
    66481 aaagttcggc ttgttgcatt atgtctcaag aagaatgaaa tatgtcgtgc tttacttaaa
    66541 tgaagagaca ttggaagaaa cagaagaacg aatccgtaaa ttacattttg ttcgaaacgt
    66601 agaacgttct taccgaccgg atatcgaaat gaattttgcc gaaaaaatag gaaacaaaac
    66661 agtattaaaa gacgaaggtt tcgaaattga agagctaaat acagaaatcc gattagctga
    66721 acatctttaa aaatctctta tgagcagttt ttaaataaaa aataacttgg ataacgatcg
    66781 atttttgatc attgtccaag tatttttttg gtatactagt accagtacca tttctaagga
    66841 gtgagtagat gcggataata tcaggaaatt atggcgggcg ccgtttaaaa agtttagcag
    66901 gggcgaacac cagaccaact acagataaag taaaagaatc catattcaat atgattggac
    66961 catattttga tggagagaca gtattggatc tgtttgcagg aagcggtggt ttagctatcg
    67021 aagcagtatc tagaggctgc agtcatgcgg tatgcgtaga caaaaattac caagcgctaa
    67081 aaatcatcaa agaaaacatc gaaattacga aagaaccaga gaaatttacc acaataaaac
    67141 ttgatgcgga caaagcaatc gaacggctag cagcggagaa acaacaattc gactacttgt
    67201 ttcttgatcc gccatatgca aaacaaaaaa taatcgatca aatccataaa atggaagaac
    67261 tgggactttt ttctaaaacc gcagttatcg tatgcgaaac ggataaaaca gtcgaattgc
    67321 cagaaactgt ggctggattc catcaaataa gaaaacagat ttatggcata acggccgtaa
    67381 ctatctatag aaaagaggga aatcaatgaa acgtgcatta ttcccaggaa gttttgatcc
    67441 ttttacaaaa ggtcacttag atacggtgga acgtgcggct aaattattcg atgaggtagt
    67501 aattggtgtt tttatcaata cttcaaagaa aagtttgttt cccccagaag aaagaatgac
    67561 attgatcaca aaagctgttt ctcatcttcc taatgtaaaa gtcatgcatc aagaaaatca
    67621 attgacggta gaaacagcaa aagagattgg tgcagatgcg ttgatcagag gcatacgaag
    67681 tatcaaagac tttgaatatg aacgagagat tgctcagatg aatcatcatc tatatgatga
    67741 attggaaact gtcttcttat tagcaaaacc agaatatagt cacgtgagtt ccagtatttt
    67801 aaaagaagta ctgcactttg gcggagatgt gagcagctac ttaccgccag tgatcaacga
    67861 agctttagct ggaaagcgtg aatcaaatga aagctaaaca atggttgaaa acagtactga
    67921 ttatcatatt tggaatgttg atcattggat ttgtagtagt tcccttgccg tattatgtag
    67981 aatcaccggg agccacgatc gatctgaaag aactaattac ggtcaatgat aaggaagata
    68041 aaggttctgg gtctttctct cttacctctg ttggtatcag gcaagctaca ggtttcttag
    68101 ctttaaaagc taaaatgacc ccttttgaag aattgatcag tgaagaagaa ttgactggtg
    68161 gggcgacaaa tgaagaatat aatcaaatgc aacagtatta tatggattct tcccaaaatg
    68221 cagcaatcga acaagcgtta aaacttgcag acaagcctta taaaatggaa ttcaaaggcg
    68281 tatatgtcat gagtgtagag aaaacatcga atttctttgg caagctttca gttggagata
    68341 cagtaacaaa agtagacggg aaaagctttc aaagtacaga agcatttatg gattatgtaa
    68401 aaagccaaaa agttggacaa acaatcgaaa tcagttattt gcataatggt gaagaaaaaa
    68461 cagcttctgg tgatctgatc gagttaccaa cagataaaaa ggcaggaata ggtatcacgc
    68521 ttactgacca taccgagatc gaatcagata cagatgttcg tattaattct ggctctatcg
    68581 gtgggccatc agcgggattg atgttcactt tagaaatcta tgaacaagtc actggtaaaa
    68641 acttgcgaca tggtaagcaa attgcaggaa ctggaacgat caacagtgaa ggagaagttg
    68701 gccgaatcgg aggaatcgat aaaaaagtgg caagtgcgga taaagctggc gtagagattt
    68761 tctttgcacc agatgatacg atttcagacg atgttaagaa agaatatcct gaaataaaaa
    68821 ccaactacga agaagcaaaa gctgccgcta aaaaattgaa ttcctcaatg aaaatcgtac
    68881 cagtaaaaac agtacaagaa gcgcttgact atctagagaa aatgaaatga aactaaataa
    68941 ttaaagaggg gttgtgacac gagttctgtc acaacccctc tttttcgtca aaaatcttca
    69001 cgataaaaat aaaaacaaaa gaaaaaattg acgtaattag atgttgaagg gacgattttg
    69061 ccagagctca ctgtttcttc aattttaaat gaaaggagta atgaatgatt tttactggtc
    69121 attctttgaa aaaagaacaa tgatagaaaa aatcagcaag aaaatactag cttcacccaa
    69181 attgatcatt tggatgtcta tgatagttct tatcttttgt atcgcaagtg gttttttatt
    69241 atcaaatttg ctattttata gagaaacaga agagactgct gcaaaagaaa tactttcttc
    69301 gtttagttcc agtggagaag atccatcagc tgaaggaaac gatgtagaag aggatgctcg
    69361 tccaaaggtc atgtacaccg atatcaaagg aagtgtgaag gagcctggta tctattcctt
    69421 ttcttcagaa gaacgggtct atgatgtact aaagcgtgca ggtggattat tagaagaagc
    69481 ggatagcgat cgaatcaact tttctgcgaa gatagaagat cagcaagtcc tatatatccc
    69541 tgctgtaggt gaagagctgc cagaacatct tgatcagttg gcatcctcgg aaggaaaaca
    69601 gcctacagca gattccgagc ctcccaaaat aaatatcaat acagccactc catcagaact
    69661 tcagcagatt cctgggatcg gatcagtcaa agcgcaagaa atcattcgat ttagagaaga
    69721 aaacggatcc ttccagaaag tggaagacct gcaggagatt tctggtatcg gtgaaaagac
    69781 agttgaaaaa ctaaaaaact tcgttacaat taaatagaat gattcaaaat cgactggcac
    69841 gagcaataaa tggacgctaa tggatactaa gaataatcca attctaagag cttggcagga
    69901 cgaggaggta gtatttttgg ataggaaata gcttgattgt tcgcaaagaa acattaaaaa
    69961 aaccaatgct gaatgtctat ctccaaaata aaatatctgg gattcatatt atgaatacgg
    70021 ctgtcagcgg caataacagt caagctctac gagaacgctt tgccaaagat gtacttagct
    70081 atacagcaga taaagtattt attctcattg ggacgaatga tctagcagag cataaacaac
    70141 tttctaaaga aacgtaccaa aaaatctgca gtggatgata gttcagctga aaaaagacta
    70201 tagttctgat catgctttct ttatcacgcc accagcagtc gatgagacaa aacaaaaata
    70261 tcggaataac aagttgatca aagaatatat ctctgttctc acagaagtag caaaacgcca
    70321 tgattgtgaa gtatcgattt ttatacggaa tttcttgaac aaatggattc gaagaatttt
    70381 tataatgggc taatggatga cggacttcat ttcggcagtg aagggtagga tcttttgtca
    70441 gacaggatga ttcgttatat ttaaagaata ttttgtttaa gcaatgagta ctttttaatc
    70501 aacttgaaaa aacggaggaa tataaaacat gttagaaaaa tcttcaaaag catgcgatac
    70561 gaataaagaa aaagttactg ataagtcaca taatgaacgc attccttggg accagtactt
    70621 tatggctcag gcagtactgt tatctttacg tagtacgtgt acacgtttag aagtaggagc
    70681 gacactcgtt cgagaaaaaa ggatcattgc tggcggctat aatggagcag tcagtggaga
    70741 tgtccactgc atagatgaag ggtgttacgt cgtggatgga cactgcttgc gaacgatcca
    70801 tgcagagatg aatgcactcc tacagtgtgc aaaacttggt atcccgacgg aaggttcaga
    70861 aatctatgtc acacattttc catgtttggc ctgtacaaag gctttgttgc aagctggtgt
    70921 gaaagggatc aattatctcc atgactatcg aaatgatcct tatgcccaag cgttgatcga
    70981 acaattaggt gtatctgtac accaagttgc tttagactca cagcattttt caaaacttca
    71041 aaatgaatta acaggaaaac atgtctagcg ttttagaaag gcatgttcga aatcggttga
    71101 tttttccggc aattacgtcg atgattatct gtttgttgta ttacactgac aattggggtt
    71161 atcgtttgct tcttgccgga atttttttat ggttttcgct aaaagaagga cgttttatcg
    71221 cgtacttgtg tattttgtgt agcataacgg tatccatttc ttataggcta caagagtatt
    71281 catttttaga ggaaaaaaca acatctgcgc aaattactgt atttacagat acgattcgtg
    71341 caaatggtaa ttttttgaca atggaaggaa ggttatcaga gaataaacaa aagctccagc
    71401 tttcttatca agtaaacaca gaagcagaat tgaaaacatg gcttaacttc cgaggaaagg
    71461 gaatagaatt gactgctgaa ggcgagttca tctctccagc aaaaaagcgg aatctttata
    71521 attttgacca agaagcttac ttcaggaacc atagaatttc tggacggttc caaattcaaa
    71581 agattgaaca gatcaccatg caaaatcact ggcgaaactg gcttcagaga aaaagaggat
    71641 cttttatctc ctttgtccaa tctgaatttc cgcaaaaaac aagtgtatat attaattctt
    71701 tattatgggg ctataaagat gcaggattca gagaaccaga agaaattttt agggagagtg
    71761 gtttgctgca tctgttcagt ctatcgggtc tacacatcca attttattta gggtggctgt
    71821 attatttgtt tcgacgtatc ggatggccac tacacgtcag tattattccg ttgagtctac
    71881 taactatctg ttatgtttct attgcaggaa gttctatttc tgttttgcgt gctagtttgc
    71941 tgtttttatt gcgattgcta gtcaaattgc tgaataagca ttattccacc atggacttat
    72001 ttgcagttgt cttttggctt cttttactat ttgatcctcg atttcttttt catgcgggtg
    72061 gacagcttag ttttttcatg agttttttgt ttatcctgat ttcttttgat ggagattggt
    72121 tgaaaaaaac ggcctctcac gtcctgttta ctatgatcac gatgccgttg attgtatggc
    72181 atttttatga gtggcctatt ttaggtagtc tttttacatt actgattgca ccggtattca
    72241 agtttctttt tcttcctggt gtgttatttc tcacactctt caatcgctgg ctgccggaaa
    72301 ctttactttt gctgatagaa gagggattaa tcttatttga gcgaataatc gatttttctt
    72361 cagggtcgtc tctcattata ggacgtttgc cccttgtgct atctgggatg tatattttcg
    72421 gattactgat ttgtatggat aggttgaaag aacaacctgt gaaacacttg ttttatgttg
    72481 gtcttttttc ttttattttt ttgactttgc catttttacg cttttcttca acgatcgctt
    72541 ttatcgatgt cggtcaagga gacagtatct ttttgcaaag tccttttcga aaagaaacga
    72601 ttttgatcga tactggaggt cagttacact ttgaaagaga aaagtgggcg caaggtatga
    72661 tacgtcctcc tgctgaaaga aatatcgttc catatctaaa aggtcagggg ataagtgtaa
    72721 tcgataaact catcttgaca cacgacgata cggatcatgt gggagaatta cccacgttat
    72781 ctcagcattt tactatcaaa aaaatttata tcggttgggg cgctggacga aatgagccat
    72841 tacaaaggca tttatctgaa gctcaaaaaa atggtactga gatcattgaa atcaaacatg
    72901 gggacaggat cagcggttat tatgatcttt atgtattgac tccttttgaa aagggagagg
    72961 gaagaaatga agattcgatt ggtctatgga tggaatataa caataggcgc tttttatttt
    73021 taggagattt gaatcaagca atggaaaaac aattgctttt gatttatcct aatctgaaag
    73081 ccgatgtagt caaattaggt catcacggta gccgtacgtc aagtaacaca gattttcttt
    73141 cccatattga agcaaaacat gggattatat cctgcggcgt aaataatcgt tatggtcacc
    73201 cgcacagcga agtattggag acactagaag aaaatcagat aaaaacatgg cgaacggatc
    73261 aacaaggaat gatcacctat cgctggcatc cagtttttca tcctcatggg ctagtggaaa
    73321 caatgataga ctagtaattc tcatctgctc atggtaggat aatttttgaa agtggtgagt
    73381 aatttgagta tacaagcaga gttacaaaaa atacgtaaag aaaaacttgc atcttgttac
    73441 ttgattttag gaacagaaaa gtttctccaa gatcaagttc ggacagaaat tgtcaaaaaa
    73501 atccaattag agggcgaaga tgacttaaat tttttaagtt ttgacatgga aaatgcaagt
    73561 ttagatgagg tagtagctga agcagagacg ttgccgtttt tcggagatca acggttagta
    73621 ttcgtagaga atccttattt tttaacaggt gaaaaagtaa acaatggaat cgaacaaaat
    73681 actgatttat tgacggctta tttgaaagaa ccattagaat cgactgtatt agtattcttt
    73741 gcgccatatg aaaagttgga tgaacggaaa aaagtaacga aacaattgaa aaaaacagca
    73801 attatcatca atgtccaaca gttgaatgaa aaagaagtac gtcaatatct gatgaatacc
    73861 ttagagaatt cctcaatcaa aatggaacga agtgcaattg atttattctt gaggttgacc
    73921 gacttagatt tatccaaaat gatgagagag ttacagaaat tggtccttta tggacaaaat
    73981 caacagcaaa tcacggtaag agaagtagaa gaattagttc ctaaaacgtt agaacataat
    74041 atttttgaca tgacccaata tattttaaaa gggaagacgg aacaagcttt gcgtttatac
    74101 gaagatttag ttatgcaagg ggaagaaaca atcaaaatta atgcgatttt gctttctcaa
    74161 ttacgtttat ttttacagac aaaatttctt gtaaagattg gttatcagca ggcaaatatt
    74221 gctgaaacat tgaaaatcca tccatatcgt gtaaaacttg ccatgcagga agtaaaaaaa
    74281 ttcgatgaac atttgctggt acagttgttt gatcaattag ttgagatgga ttatcaaatc
    74341 aaaacgggac aaatcgaaaa agaattaagt tttcaactat tcgttttgcg cacagggcag
    74401 ttgttaagaa atcgataaga agaaagacga gggcaaagca tgcgggaagg tcgtttgttt
    74461 ttgtcctttt tttgacaaat aaaaaaatcg gccgaagccg attcttttat ttagcgattt
    74521 ttttgcttaa acgagatttg tcgcggttag ctttgttttt gtggattaga ccttttgatt
    74581 cagccatatc aatagcttta acagcttctt tatataacgc atctacgttg tcagcacctg
    74641 aagctacagc atcttcaaat tttttgattg cagtacgcat agcgcttgtt tgagatgaat
    74701 ttttcacatt agcgttttcg cttgtacgaa cacgtttgat tgcagattca atgtttggca
    74761 ttagtttcac ctccgataac ttaagttctt acgcgtgtta ccgcataatt caacattcat
    74821 tattatacct aaaggcagcg tgctttgcaa tatgaacatg acaagttttt ttccttaaca
    74881 gtcttttatt aggatttttt ttcagtaaaa acggatagta caagctgaaa aaaatcaaaa
    74941 agacgctatt gtgggaggca atagcgtcaa accaaactag atttttattt atctatttaa
    75001 acaaagtttg aatgggaatg tttggtacta agttattata taacaaagag aaccgtttgc
    75061 aaagtttttt ttgaaaaggg atacgattcc ctgttgttct ttgtttttct attaagaaac
    75121 tgcagttatt ttataaccag tatcctttga tcagtaaagg ctattctggt gtaccgatta
    75181 ttttaatgta ttcatcgata ttttttatca acattttttt tatgaccaac tggttccgac
    75241 ggttccattt gccacttact tccagcacat atttatttag gggcaaacgt aagatatatt
    75301 ttgccaaata gcgatcttta agcaggccat tgatcacacg gtcctcaagc tgcaagttga
    75361 tcccagtcag catcattggc tgttcttgta aaacgtacgt atcaattaaa agaccttcaa
    75421 aagtttccac aagcgtcttc ctttcttttc aaagtaacct gaaaacaggc actaattctt
    75481 ccattttgat attcgttgaa gtggatgcga tcattctttc ttttgtccac tgtaatctag
    75541 tataacaaaa aagagcagaa gagccaaaaa gaaaaaagag catcgaattc tataggaagt
    75601 ctcattggca cggcctaaat tattacaaaa cattgattaa aaaaagcccc tgcatcgcag
    75661 gagcatcccc tatatcgttt taataggtca atcaaaaagc agtatcaaac acattttgta
    75721 tcaaatcagg aaataataga taagctaagc ccagaatcaa aagtaccgct agaagaaacc
    75781 agccgattgt tcctatgaaa tactttaatt tttcgaacat tgtatcacct cgttgtcagt
    75841 atatcacgga tcagtaaatt gggggtgtta agaatctcct aaaatagaca aaatttgttc
    75901 tattttccta aagcaaatac ttgtaagata cagtaagtga taccagaagc aatgaccggt
    75961 ccggcggcga ttcctcttaa gaagacaaca cctaaaatcg tgccgaaaac aagtgcaaca
    76021 gtgatttgtg gatcagaagc aatcaatcct acacccttgg aagataagac agccactagc
    76081 ccaccgcaaa aaacagctac ccagccaata ggggatttaa aggcttctaa tagatcacgt
    76141 agaccgattt ctcctgttgc gatagggatt agaatagccg ctgtgatgat cgtcacccca
    76201 atattgattc ctttgccttg aagccaaggg aaaaaggaac gggaggctgg tatgagcttc
    76261 ataatcaaaa caaaagctgc cgctatcatc agactttgat ttttagctaa aattgctaca
    76321 agtaaaataa ttcctaaaaa aagccaactt tccatgaaat atattcctca ctttcttcga
    76381 aacaatcata acatgttttt agaaagttac aaaagtagga attcatcctt caagacctat
    76441 tcataagctg tttttttcat aaaataaaca aaatcataaa aaaacacttt gcttatttga
    76501 cagaagacag ccgcgctttg tatagtggac aagacttaca tttttttgaa gaatcagaaa
    76561 gatcaggtaa aggtcttagt aaacgcaagc cattcagaat aaccaatatt gtgcttcctt
    76621 cgtgtcctac aactccaaga ggtagattta aaaattgcag gaagttagaa gcaatcaaca
    76681 agagaataac aagaatcgaa aaaataatat tttgtttgat gatccgccgc atttttaaag
    76741 atagccgatg actgtagaca aatttattta agtcgctttt cattaagacg atgtctgcga
    76801 tatccatagc ggcatctgtc ccttgcccca tagcgacacc taaagaagcg gctgctaaag
    76861 caggcgcatc attgactcca tcaccaacca tcgcatttac ttggtaaagt tcattctctt
    76921 ttttgactag ttgtgttttt tcttccggag tacagcttgc atagtaatgt tcaatcccta
    76981 cttgttcagc aatggccttt gctgtgccag aatggtcgcc ggttatcata cttgtatgga
    77041 tgttttggga tttaaagtag gaaattactt gttgggtatt tgcttttgga atatctagca
    77101 gacctaaaac agcaattaac tgctgatctt tagaaagata aatcacggtt ttgccttgat
    77161 tttccaaacg ttcgatcatt tccgcaatct ctttgctgat tatcatcgtc tcaggatcat
    77221 atgcgtgctt gccaactttc cattgcgcac ctaaataggt agtttgtaat ccaaaaccag
    77281 taatttcttc tattggtaag tattggattt cttcaggtat tgtgcaatcg aaatattgca
    77341 aaatcgcatg agcaagtgga tgcgtcgttt tttgttccat agcaacaaga agttgttgtg
    77401 ccaaatcctt ttcatcaaag aaaaagctgt cagttacaac tggttttcct ttagtgagcg
    77461 ttcctgtttt atcaaaggca atcgctttta attcagaaag cttttctaaa tggataccgc
    77521 ctttgattaa aatcccattt tttgcagaat ttgaaagagc agctagagaa gctggtgtag
    77581 cagatgcgac aagcgcacaa ggagaagcca caactaataa taccattcct cgataaaagc
    77641 tttcatccca actccaacct aggaaaaagt gggggagaag gatcattaga ggaacagcaa
    77701 gcaaaatcaa ttttacataa ttattttcga ttcgttcgat aaatgaagct gtttgagttg
    77761 gcgtattctg cgcttcttct actaattgga taatcttagc aaagacagtt tcggaactcg
    77821 tttttgttac tcgaatcgtg atgggatttc cttgattcag cgttcctgca tacatctcat
    77881 cgcctaaata tttttctaca ggcacagatt caccgcttaa tgcagactca tcgatcgttg
    77941 cctgtgtgct ttctaaaaag ccatctatcg gaacagctgc tcctttagcg acaaatacca
    78001 agttatccac ctttagttga gaaacatcta cttcttgcat ttgtccattt tcttttaata
    78061 attgggcttt ttgtggttga agattcatca aagcagtaat ttctttttga cttttattag
    78121 ttgtgtattc ctctaatgca ccgcttaaac aaaagatgaa tgtcaacatt gctccttcaa
    78181 agtaattacc gatcaaacag gcaccaatag cagctaaagc catcaataaa tccacattca
    78241 gtgtccgatc attccacaat tctttcaagc cttccgatgt ttgtttatat ccaccgatga
    78301 taatggcact gatataaaaa agtggggtga tggtaagaga gaatcggtcg aagataaaac
    78361 cgaagatcat aaataaaagg cagccgattg ttgctgcaaa agcttttttc tgattagtca
    78421 tcgttattag acctccttgt caaaacaagg atagcataat aaaaatgtaa ttgataataa
    78481 taacagctaa atgagaacga taatggttat catttggtga ttaagcttga tgttgttttt
    78541 attatttata atgattatta ttaaagaaaa taaaaaacca gaacatttct caaataagag
    78601 aagtgttctg gttttttcta cattgcaata aaccaataac caatcaaaat gataccaagg
    78661 ataatacgat accagccaaa agcggtaaag tcgtttttct tcaaatagct tagtaagaat
    78721 ttgatagcta agacggaaac cacaaaagat acgaatgttc ctacaagaag aacaacagtt
    78781 tcttccattt tgaatgaatt cccttcagct aaatatttga cgatcttcaa gccgcttgcg
    78841 ccaaacatga caggaatccc taagaaaaat gaaaactctg tagcgacaaa acgcgaagca
    78901 ccaatcaaga tagatcctag gatcgttgcg ccagaacggg atgttccggg aacaagtgcc
    78961 aagacttgga ataacccaac aagaagagct gcttggtacg taaagtcatt cagagaagtc
    79021 caacgaggtg ttttgttttt gttgcgtttt tcgacaataa taaaggcaat accgtaaacg
    79081 atcaaaacaa tggcaactgg taagaacttg tggaaatttg cttctaacca atcatccaaa
    79141 ggcaaaccaa tgatgatggc tggtatgcaa gcaacgatca ctttaaacca aagtgtccac
    79201 gtatcttttt tttctaccgt tgatttactt ggagaaaatg ggtttaactt gtgaaaataa
    79261 agaacgacga cagccaagat cgcccctaat tggataacga cattgaacat cgacataaat
    79321 tgtgaactgg catccagttt gatgaattca tctgctagga tcaaatgacc agtactactg
    79381 atgggcagcc attccgttat tccttcaata ataccgagaa tcactgcttt gataatattt
    79441 gcaaaaaaca taaattcctt ccttcccaat taagatacat cttatagtat accgttattt
    79501 tttgagaaac ccaatctgtt ttttaatatt aagaaaaact tgagaaataa agcagataag
    79561 tacacgaaga gaaaaaagaa gacaaagccc tcgttcagac tttgcctttt atgattctct
    79621 ggtaaaaatt aaaatatccc cattatagaa acgagtcgcg actatgtgtt ttcccgttat
    79681 cgatataaga cgtatcattg atgccgtgga tagaaaatcg accgtttgca taagtgacct
    79741 ttgttacgct gccatttaaa agcccagcac gaacaggctg tttaggatcg atcagattaa
    79801 gcaaaaaggc gatcgtcaaa ccatgagata cgactaaaac atttccacca ccattttttt
    79861 cgcagtgatg ggcgatatct tcaaatcctg tccatacacg gtctcgcaat gtttcataag
    79921 tttccgccca cccagcggta tctaagttgt atacagcatt agcaatttgt tcaaaagaaa
    79981 cttctgtggt aaacatttca tcatatgttt taaaattcaa tacacgaggg atcacacccc
    80041 acatttccat gtcatatcca ccttcaagag acccgaaaca ccattctcta atcctttttt
    80101 caataaaata aggaatttct tttcccttag aatgttctcc tagaataata cgggcagttt
    80161 cgattgcacg accactgtca ctagaataag caaatgaaaa gtcgacattt tttaacccgc
    80221 gacctaaata atgaatgcct tcttgtcctt gctttgtgag gggtgtatca caccagcctt
    80281 gtactcgttc aattgtattg aacatcgttt ttccgtgtcg tacgatataa agtgtagttt
    80341 ctgtcatttt attctcctcc taagtcgttt taacgattga aaaaaggatt tgtccttttt
    80401 tcctgttcaa tcgtcgttgc atcgccatgt cctggataga ctgcaaattc atcaggtaat
    80461 acaaacagct gggtccgaat actatgaagt aattgttcta aattccctgt atacagatcg
    80521 gttctaccga tacttcctct aaacagggcg tcgccagaaa cgacaaaatc atcaaaaata
    80581 aagctgacgc ttcctataga atgccctggg gtagggacga cgcgaaaaga catgtttcct
    80641 aaagtataag ttttcatttc aaattcatat tctgcaggcg agacaataac atcagcaata
    80701 tcatcatgtc taccgagtcc agaaagattc aaaatcggat cacctagcca tttttgctct
    80761 agtgggctga cataaactgg gatttgataa tacgcgcgta aaggttccac tgcaccgata
    80821 tgatcgtagt gagtatgggt aagcaaaatc gctaccggct gttggtttgt ttttttgatt
    80881 tcttgtttga ttcgttccgc atcttctcca gggtcaatga tcaaaagtgc ttcttcgttg
    80941 tagaccaaat aacagttttc ttcaatcatt cctgttttta atctttcgat atgcatgtgc
    81001 attcctcctt gatagccaaa acttctttca tccattagta taacgcattc attgctagga
    81061 aacaaaaaca ggtacttatt tctctttact tatctgaatt atcagactat atgaaaagta
    81121 tttggatatt ctaaagagaa ggaaagtaag ttttcatagc attttaatat gtccttgtta
    81181 cattagattc atccaaaaat ccaaattcta tatcctatat ccctgcctaa tcagcagggt
    81241 gtttttttat gtttggaaag agagctcttt ttgctaaact aggttttttc aggtaatctt
    81301 agagagaaag aggtggtgga aatgatcaaa cagtcaaaaa tatctgtgcg gcacttagta
    81361 gaatttattt tgcgacgtgg aagtatcgac aatcgtaaaa aaagtaacca tactgcatta
    81421 gaaggagcga gaatccaccg caagctccaa aaagatgcgg gagaaaacta tgaaaaagaa
    81481 gtctttttaa aaacaacagt tcaattagat gaatattacc tgatcgttga aggccgtgca
    81541 gacggtattt tcaaaagaga cggtatttat tatatagatg aaatcaaaac ctccgaacca
    81601 cgatttgaag atttagaacc agaacaagtg gaacttttct ttcatcaagc aagggtgtat
    81661 gcctatatct atagtcaaga acatgattta caagaaataa atctgcaatt gacttacttc
    81721 cagacggcag aagaagtgat cacgagaaag gttgaacatc agacaagaga gcagttagaa
    81781 acttttttta aaaagctgac tgaagattat aaagaatggc ttgtttttca agaaaactgg
    81841 cgcactgtac gcaatgcctc tttgatggct ttgaaattcc cccatgatga gtataggaaa
    81901 ggtcagcgtg aactagcggt agctgcttat aaaacgatcc gtacgaaaca gaaattgttt
    81961 gtagaagcac ctaccggaac aggaaaaaca atctctacgt tattccccgc tttgaaagct
    82021 gtaggggaag aagagggaga aaagatcttt tatctaacgg ctaaaacaat aactagacaa
    82081 gtagctgaag atgctatgac agcattaaaa gatacaggag ctgaagtaaa aagtgtcact
    82141 ttgacggcga aagacaagat ctgcttttta gatgagacga cctgtaatcc agatcagtgc
    82201 ccatatgcca atggttatta caatcggatt aatgaaggtt tatgggatct tttgaatcat
    82261 gagaatcaga tcactcgtga agtcatcgaa acttatgcaa gaaagcatac actttgtcct
    82321 ttcgaactat cattagatgt cagtatctgg tgtgacgtaa tcattgggga ttacaattat
    82381 ttatttgatc caactgttta tttaagacgt ttttttgaag atgaaaaaaa cgaggactat
    82441 ctgtttttga ttgacgaagc acataatttg gtgaatcgtt cccgagagat gtattcggca
    82501 gaactatctt atgaaaaaac gaaacgaagt aaggaagcta taccaaagga attcaaaaaa
    82561 cttcatcgcc gtttcaacaa actattaaaa gaatttgatt cgatccgaga aatagcaaaa
    82621 gaagatcatt gggattatca tcatcaaaaa gcaccggctg aatctttagt aaaggcaggt
    82681 tatcaattaa gcgaaaaaat taaagaatgg ctggcagaat ttcctgagca cccatcacaa
    82741 gaacaattgc ttccttatta ttttgatttg cttcattttt tgaaggtcag tgaattttat
    82801 gatgatcact acgaaacaac agtcgaaaaa acgtatcgcg atctgatagt aaaagagttt
    82861 tgtattgatc caagcttgtt tcttgagcag tcgttggata aaggaaaaag cagtattctt
    82921 ttttctgcta gtttttcacc actctcttat tatcaggaaa cactgggggg acaaaaaagt
    82981 ctggcttaca aactgccgag tcctttccca gaaggaaacc agcaagtttt catcgcaaat
    83041 tacctagaga cgacttatcg aaaaagggaa cacagtctgg caaaattagt agagacgatt
    83101 catgcttttg ctgatggaaa ggtcgggaat tatttcgttt tctttccttc ttatcaatat
    83161 ttagatcttg cggtggaagc attcagacag caatatcccg acagcaatgt gctaatccaa
    83221 gaaacggaca tgaatgagga agaacgcgaa cgatttttaa caaaatttca aacaaatccc
    83281 gctgaaacat tgattggatt ttgcgtactt ggcgggattt tttcagaagg aatcgatttg
    83341 agaggggacc gattgatcgg cagtatgatc gtaggtgtag gtttgccgca gatgaatcat
    83401 gagcaggaac tgatcaaatc atattatgat gagaaggaac accttggatt tgcttacgct
    83461 tatcagcttc ctggaatgaa caaagtcttg caagctggtg gtcgagtgat tcgtggcatg
    83521 gcggatcaag gaatcgttgt attggcagat caacgatttt ctagtttttc ttatcgacgt
    83581 ttattcccac aacattggca aacagcaaga gaagtacgaa gtgttgggga attggaagaa
    83641 ggaatacagc gtttttggtt atcaaaagaa gcagtaaatc aaaaaaacga ggaatgacag
    83701 acgtcagcct cgttttttga ttaacgatag ttagtgaatt gcaactcgat tggtaagtca
    83761 agtttacgta ataaagcaat cacagcttgt agatcatcac ggttcttacc tgtcactcta
    83821 atctgatctt cttggatttg tgcttttact ttcagttttt catttttgat agctgtagtg
    83881 attttcttcg cgttttcacg atcgattccg ttgaccaaat cggcagtttg tcgagctttg
    83941 ccacctagag cgtgttctga ttcggaaaaa tggatatttt tgattggcac atttcttttg
    84001 atcagcttac caaataatac atctttgatc tgttcgattt tgaaatcatc atcgctcaat
    84061 acaactagat tgctgttctc taatttgatt tctactgtag aatccttgaa gtcaaagcga
    84121 ttggacaatt cttttgttgt ttgctgaatc gcatttttta cttcttctgt attgacttct
    84181 gatacaatgt cgaagctagc atcttttgcc ataggaaccc tcctgatata catataaata
    84241 tttaccatac atctatctta tcataggatt agggcagatt cttacctgtt tgctaaaatt
    84301 cttctcattt gagttcgaag tattttattt taatagataa actgttattc ttacatttgg
    84361 aataccaaag taggggagag gtgcttgtga gtaaaattat gactgcgtat cataaaaatg
    84421 aaagattaaa gaaaatagtg gttattttga taaccggatt gaccgctgcg gtcgctttaa
    84481 attatttttt gattccagcc aatgtctttt ctgcagggat gaatgggatc gctcaaatca
    84541 tttcctcgct tttatatgaa tggtttcata tcaagataga cacaggaaca tttatttttc
    84601 ttttgaatat ccctgtgttt gtattagggt ttctcaaagt aggaaaacga gcaacgatcc
    84661 ttagttttgt gaatgttgta tgtgtatcgg tgatgacgat gctgcttcca gtcggacaga
    84721 tcactgataa tattttgatg aatgccctag taggcggtgt tttattaggt cttggcgtag
    84781 gattatcttt aaaaatgggc tttacaactg gtgggatgga tatcatctct cttgtacttt
    84841 cacaaacaac tggaaaaaca gtcggaaact acatgctgat tctaaatggt atcattgtag
    84901 tcatcgcagg cttcttcttt aactgggaaa gtgccttgta tacgattatt tccatttatg
    84961 caatgactca agtaattgat gccatccaca cgagtcatca aaaagtaaca gcaatgatcg
    85021 ttaccgtcaa gccagaagag gtaacagaag aactagcaaa acggatggta cgtggaatga
    85081 cattactgcc gtctgtcggt ggctattcaa aaaaacaagg gaacatgatc atgatggtca
    85141 tcacccgcta cggaatgtat gatcttgatc agatcgttca tgaaatcgac gacgatgcat
    85201 ttatcaatat tttaccaact cattcagtat ttggccggtt tgcaaatgaa aacgaacaaa
    85261 aaatgtatcg aacaactggc gtattgccag aaataaaaaa tcgttcacaa aaaaaatgag
    85321 gaatcaggtt tattttagaa taaatttaat ctattacatc taataagaac atttttataa
    85381 atttaaacga gaatcttact tctaaattct catttacaag cagctaaaaa aagagtatga
    85441 taaataaaaa tcgtgttaag gagtgtcgta cgatgagcga agcaaaccaa gaacggtctg
    85501 gacaagaaat agaactaatc aaagaacgta ttcttgctgc cttggaaatg gtgattgatc
    85561 ctgaattagg aatcgacatc gtcaatttag gcttgattta tgatatagaa ttcaatcctg
    85621 aaaatggaga aacagtcatt aagatgactc taacaactat gggctgtcca ttagcagata
    85681 ttttaacaga atctatccat gacgcattaa aagaagtgcc agaagtaacg aaagcagaag
    85741 tcaaactagt ctggtatcca gcatggacga cagataagat gagccgttat gcacggattg
    85801 cgttggggat acgatagaaa tcttggctga ctagctatga gaagcaaata ggaaaaacaa
    85861 aaaagccttt tatcctttct agaagaaaag agataaaagg tttctttgtt tataaaattt
    85921 tgtctgctat attataagtt aattaaataa atgtgttcta ttgataaagg acattcaaat
    85981 ccctttcctt ttggaatcct tcttttttac atcagtttga ttttcgtata gtattctttc
    86041 tcatcttcac gataaatcgc agccccattt ttttgttgtg ctttaagact gccaagattt
    86101 tttttattta cagacaaaag tgcctcatca atgccgattt tttttgcctc ttgtagtact
    86161 aatgctaatc cttgtgtggc atatcctttt ttacgataat taggggagat gccgtaacca
    86221 atatggccag cgccgtttct taatgtttcg ttcagtttat ggcgcaaatt aaaaattcct
    86281 acatactcat gttcatcact ttctaaaata aagacggttg cgggaacgta actctcagga
    86341 agatcgattc ctaaagacgt tttttcgcat ttttttacat aatctaaaaa ttcagcaaat
    86401 gtatagccat aagcattgtt gataaatcca ctctcatttg gtccaaagct agtttgtagc
    86461 tgataagctt tctttaaatc tgcttcccat agtttgatca gtttcatcgt attcacctct
    86521 ttaagtaacc ttattcattt gttttctact atagcactat tgttgtaaat agccatgcct
    86581 atttttattt attgtgtcat atcgtattaa gaatcatcga acaatacaaa tatgaattac
    86641 aataaaaaaa ttatttgaag ttcgttcatt cgttacttat gatctctaga agaaagaaaa
    86701 cgtgaattac ttcagcgtct agaattccag aaggatagta atcaacagaa gaaataatca
    86761 atatccaaat gaaagaagat agctgaatcg agaaaaagag gaaaaaagaa atgaagaaaa
    86821 aaataaaata gttactaatc ccagagtcgt tcgtttaaca ttgaaatcga tcatatggat
    86881 aaaacagatt ttttcaccaa ccctcaatag atgatggagt tgctcggatg aattatttgt
    86941 gtagatggca taagggaggg cgtacagaaa tgaaaaagaa caaaaatatg ttcttgacaa
    87001 aaaacacatg taatcctaaa ctaaaagatg tgatgcggct atggcggaat tggcagacgc
    87061 gctagcttca ggcgctagtg agggtgacct cgtggaagtt cgagtcttct tagccgcata
    87121 atttgttttt ttataaagag aaggtacacc tggagcgatg agaaagaaaa taacatatta
    87181 tctaaaagaa tataggaaaa attttaaaca acggaaccag attcaaataa atcaaaaaaa
    87241 atttgtgtga aggtgggaca gtttaaaacc taatagattg attcaaatag tagatttata
    87301 gattctgata caagaaatac tggcaaacga tagttaagga ataaagacta aacttaaact
    87361 caaaaagagg tcatgcgaaa gaataaatcg catgacctct tactatattt tgaatgtgtt
    87421 taaacgttca aataatgaat cttagtacca accgtttgct tcccagaatg ctttcgccgc
    87481 ttcccaagaa ccataacgtg aagtaacata ttgttctgct actctttctt ggtttgcagc
    87541 agagtagtca ccatttaagt aagaagaatc taattggtaa cggccgatgt aacgtccgtt
    87601 cgttgctgtg taagaaccgc ttgattcttt ttgtgcgatc cattcttttg cagagcttgt
    87661 acttgctgga gtagcagcag tttctgttac agcaggagca ggttgtgttt cagcaacagg
    87721 cgctgcttgt gtttccgttt gaaccgtttc ttgtacaaca ggttgttcag cttgaacagg
    87781 ttcagcttgg actggtgctt cttgaacggc tgcttgaggt tcagcagctg cttgtgcaga
    87841 gccttctgtt gggattgtta attgttgtcc tgagtagatc aggttaatat cagaaattga
    87901 atttgattct gcaatggcat tgatcaagga gttatcacca acgtattttt gagaaatcgt
    87961 tgatagagta tcacctgatt gaacggtata agcttcgtcc gcatgagcag tcgttcccat
    88021 gaagaatgca gcgccggcag ccaaagttgt tccaaaaagt aaagttttaa gtgatgtcat
    88081 gaaaaatctc ctttattcgt taaaaagttt tatttgttgt gttcaacgag gaatacttta
    88141 acacgtgaaa atatttcata ggtaaaagaa gcatgacaat ttatgacaaa tccacgtttt
    88201 ttgtaacaga atgatgttcg ctcgatgtga aaaatgatga ggaatttcac ataatgcaga
    88261 aataatggga ttagaacagg tgttctgatg agaaaagaaa tgtataaata acttgaaaga
    88321 aattgctttt gttcatcatt ttatttacat attgcgtata ttttttgtat ttttgcttga
    88381 gatgttacaa taaaagaaaa aggaggcggt tccaatgagt aaaagatacc agaacatcat
    88441 ggtagcagtt gacggatcaa gacaatcgat caaagcgttc gctgaagccc ttgacttagc
    88501 aaaggacaat gaagcccact tatttatcgt gtcaatcatc aacaaagttg agctgaccca
    88561 tagtgcctat gccttttcaa aaatctatgc agatgaaaaa caaagaacag aagtagccat
    88621 gctgaaaaaa atcaatgatg ccaaagagta cggcattgct gagatccacg caatagttga
    88681 aactggagat ccaagaaatt tgattgccaa tgtcatccct ggacaagaaa atattgattt
    88741 gatcgttatg ggagcgacag gaaaaggtgc tatacaacaa gcattagttg gatcgaccgc
    88801 ttcttatgtc gtatcacatg ccccttgcag tgtgttggtc gtgaagtaat gagataaggg
    88861 aggaatagaa aatggttcgt cctcaagaag tccgtgcgcc aaaagaaaaa atagaaattt
    88921 tagcaattat tgaagacggc acacaaacaa agaagggata ctcgatcgct ttagtaaagt
    88981 ggaaaggaaa aaaaggtgtt gctctgagat gggatggaga taaccaacaa gataaaggat
    89041 tccctgtcac agctaacggt tatcatccag cgtggtttgt tctgcctgat aaatttatgg
    89101 aattatacag ctatgattat gcaagagccg cagcatcaat caaagcatta gataaattaa
    89161 cagaagagca gaatgaaatg gaggaaaaat aaaaaagacg aaccaatcag cctttagaaa
    89221 actgattagt tcgaggagta aaaatgaaaa aaggttattt gggatgaaac tagaataatg
    89281 cgtataactt aaataaaact taaagcaata aaatggcaag agggtgaggc aaatggaagc
    89341 aggaaaagta ttacaggaag taaaagcact atgtgcagat aaaaaatatg aagaagcgaa
    89401 aagcctgatc gaaaagaaca aagaaaattt ggaagaaaag tacccgatcg cacaagaatt
    89461 tatagaatta aaacaaggaa cgatccttca ccgattcaaa catttttttg gtataacaga
    89521 atagaaaaaa cgattaaaga tcggcagaaa tttgctgcat ctttaatcgt tttcttttta
    89581 aacatgcgag ggattcaatt ctgattctta tataaaaaat agatccaaat aataagaaaa
    89641 attactgaaa gcgtcaattc gatgatgtgt gttattaata cagacgttgt ttcccaatgc
    89701 ctaaaagaaa aaatttgata agtaaaatat acagcaggta aagaggccag taaaactgaa
    89761 aacttctttt ttgtccattt tatgtaatag aaaagaatgc ttatcataat aaaaaaagga
    89821 atataaaaaa caaattgacc gatcgcgatc atactattgc ctccgataaa taaagtccat
    89881 gatacaaaat aacactttgt gcgaaatggc gcaagcagtt ttgtggattt atccggtaaa
    89941 atctgtatcg attttgaaat tagaggagaa acttgctata atcaaagtga aagaaggagt
    90001 gggattttca tggatcatgt agtgttagaa atcgatttgc atttgatcaa taatattcgg
    90061 gtgatttact atgttgtaag taacagtgtc gaacaacgtg tactgacgaa taaaataaat
    90121 ggtattttag caaagaaaga cgttcaccga ttcaataatg gtgaaggaag ttattatagt
    90181 atcccagtag aaaaaattat ttatacgaca gtcaaagtca gagaagatct agataccaaa
    90241 aaagcatatg aacctatttt tacaacttat tgattgacag cagatggagg aaaaaaatga
    90301 atccatatga acaacttatt caagatttga tcgatggaaa aatcgaaaag attgatgtaa
    90361 aaagagaaga attaatggct tttcgagaag cgtggctgaa gttggagaat cgtaaatatg
    90421 tggtgggaaa agcctcactg aacggcaatg tgacttatca ttacgatccg acacgtttat
    90481 tttagtatga agtattcaga aaagaaccaa aggaggacga tgcagcagca ttgtcctcct
    90541 ttgattttac aaaagtgaaa gttttactta tttgaataga tttttaaatt tgtttttgac
    90601 actgtcgata tttacatctt ttaaaagatt ttgggctttc tctttataag gtcctaattg
    90661 ttctttatgt tcttcgataa atcgttttgc gccatcgaaa ttgccgttct taatcatttc
    90721 cttgactttt tgaaataatt cttcttgatt cattttgaac acatcctttg ctatcaacat
    90781 gattttttac atggacaaaa cgagaaaaac tgatttatcc acacgtcaat aatatcaaat
    90841 aacgatcatt tttactaaaa aaacactcga ttctcgcttc taaagtagga gaaaaatctc
    90901 caacttggga cggatggaat ttctttaact gacccatata ctgaatatat aacaaggagg
    90961 tagaaagatg aaagtgatta aatatttgat tggactggcg gcgattagtg gtattttgct
    91021 atttggactg aaatattata ctgaaggaag ttatggagaa atccctggta tacttgatca
    91081 gctaaatcca ttagttgaaa aaggagaggt ctatgtaaag acacaaaaac cagaggaagt
    91141 aaatgaatat ggtacagcaa ggtatgtgca gaaagctgct gatgccaatg ggaaagaacg
    91201 aacggttgaa tttaatggtc tttctgtgtt aaaagaaaat cattatttga aaattagcaa
    91261 taaaggagca cacatagaaa cgtatgagga agttcctaga gaaaaagttc cggagaaagc
    91321 attagcaatt attgggtaaa tcagtttttg tattaagaat acgcccgatt ttattattca
    91381 taatttaatt atgtaaacta aatacaagta gtaaaaataa tacaataatc cccctgcaaa
    91441 aagattgttc ttttacaggg ggttcatttt ttcagcaagc acatcaaatt gggatggcag
    91501 ggttcgaacc tacaattgct tgattcagag tcaagtgcct taccagtttg gctacatccc
    91561 atttattcaa caaaataatc atagcacttt cctaaaaaaa cgcaagttat ttttcttgat
    91621 cggatagttg ttgctttact cgtaaaaggc ggcgtactag tttcttttct aatccagcag
    91681 gaagggcaat cagttctgct actgacaaga cggtgtccaa taactgatat tctttgacag
    91741 gttcattcat aatatgatag atgtttgcta aacgttcaat atattcaaag cgagtatact
    91801 ctgttcgagc aattagaaat ttcaataaat cggtggcttt ctcgtactct tgatctgcgt
    91861 aataaacaag agattgacga tacaatttga tttccagttc attgagggta gcaggtctgc
    91921 gacgctcgtt ccactcatta atagagactt taccttgaac atttcccttg cagtcacgga
    91981 caaaaataat cggaatttca tttggatcca tttttttatg tgtgaatttt tccattatct
    92041 acgctccctt caaaggtttg gtatcttgag tataagggat ttttgtttga attactagct
    92101 tttctccaaa gttagcatct gtccacccat tgcagtgaaa atcgccgaaa aatcgttgat
    92161 cggtactgct cgatttttta caccataggg atcgttgaca taaatatttt ctttgtcata
    92221 tccagtgact acacaagcat gaacaagagg agtgactctt acttctccat tatttgtggt
    92281 ccaagtcata aaatcagttt catctgggac ttcaaaattg atagtcacag aagtccagac
    92341 aggatttcct ttagatagtg cttttttgat atcatcgagt tgagcatcgg tttttggaaa
    92401 agtgtgataa tccgtttgga cgatttgctg agcaagggag gcaactgggg gaacatagac
    92461 gaccatagcc cagtctccgc cactgatatc accaacaaat ccttcattag gatcgccatg
    92521 agtcccatct gcattgaaaa cagggacgta atccaattgc tcagctaact ggtttttagt
    92581 tgtttcataa ccataaaaag ataaaagcat agaaagcgaa gtgacttcac agccattttc
    92641 taaagaagga gaatcaaact ggctctctaa tggaacatct agtaaaactt ctgctttctc
    92701 ttttgtcttt ttcgtttttt gtgttgaact tttttgtgca gtgttcattg tatgttctgg
    92761 agaatggata tgtaggtaat aacttgtacc gcttaataaa agagcagctg tgccccctag
    92821 aaacaatagt tttttgaacg tttttttctt catttgaaat ctcccttttc agctgtttat
    92881 ctttcctatt ataaatgtat ttttattgga aatggaagta ttatatttta atatgtagga
    92941 aataattagt ttttaaggaa tatgttttaa ttttttgaaa aaaattcttc taaatacaac
    93001 agctgtttta attgtgaaaa cgaaaacagt acgctataat gcctgtaagg ttgattttta
    93061 actgtaaata aaaatcaatg agttaaatct ccaaagaaat agcagtggta atgtggagaa
    93121 aagttccagc agtttaggag gattttgatg acggaagaaa tgattaattt aggagaacaa
    93181 tatgcatgca aaccaattgg ttttacaaaa acggtcattg gtgaagttgt atcaaaaatg
    93241 acaaactgcg ccgtggtcaa agttgcccaa tgtgctgcag aggaccaaga attattagat
    93301 gaaaaagcaa gcatggttgt tgcaaaatat gatacatttg aataaagaaa acaattggac
    93361 gtgcggcgtg ctgcaagtcc aatttctttg agaaggtaaa tcagtattct tttcctattt
    93421 tctggagaag aaaaagcgag gcgagttgtc atggtaacat tctttacggt tctattgttt
    93481 ttattcgttg ttgtgatgtt tttatttctt tggctggttc gaaaagaaat tatttatcgg
    93541 actgtgcgaa atcgatgggt ctacttggtg atacccttct tagtgtcact agtcatttgg
    93601 tatacactca tcagtcatcc tacagcagat gaattggcaa aagggatctt gtcagcaatg
    93661 atttttatta gttttttgtt ggacagtaga ggaatcacag aagaaggact tgttttgaat
    93721 agctttgaca aaaaaggtgt tcctttttct gagatcaata aaattgtatt atatcagcca
    93781 aaaggttcta aaatcgtaaa aatgaatttt ttccgaaacg gatggcgagg accgatgctg
    93841 aaattttctg catcattaga agaattagtt ccatttttgt cccaacgctt aaacgatgag
    93901 gcagagattg atattatgat tgatccagaa taaaaacaga ggttgcgaca agatgtttgt
    93961 cacaacctct gttttttatt tcaaataaaa ttatccaaat acgcggaagc gatcggcatc
    94021 gttcatgtat tctttttcct cagccggtgt ttctggtgaa ccgaatacta attgcgaacg
    94081 tagtttccag tttgaaggga tattccattc ttttgcaact gcttcgtcaa taactgggtt
    94141 gtaatgttgc aagtttgcgc ccaatccttt atcaactaat gctacccaag tattagctgt
    94201 tgcgattccg tttgattgtt ctgaccaatc tgggaagttg tctgcatata attcaaattg
    94261 ttcttgtaga ccttttacca cgtcagtatc tttgaagaat aatactgtac cataaccatt
    94321 tttgaaacca gctaatttgt tttgtgtatt tgggaaagct tctgctggag tcaatgggcg
    94381 aagtgcttct tcagtgattt cccaaagttt ttcatgtgca tctccgaaaa ggataactgc
    94441 gcgtgttgat tgagcattga aagcagttgg gctttcttta attgcttctt tgatcaaagt
    94501 tgttaattct tcattagaaa gtgaaacatt acgtcctaga tgatagattg aacggcggtt
    94561 tttcaaagtg tcagtaaaag ttgtcataat aaaatttctc ctttgatttg cgttttgcat
    94621 ttttttaatt gattacgaaa tgaagtatag caccttacaa aaagtaagta aacagatatg
    94681 ctcacaaaaa ataagcgaag ttcaaaaaac aattttaata agaaaaatcg ttatgtaagg
    94741 attttcttag ttatcgcttt cattgttgtg ttttaggaat ttttgcttat ttgaaaaaaa
    94801 cagctgatat ataattatta aatctctatc ttcttttttt tatgatattg ccattaaaaa
    94861 ttacttgctt ttatagaaaa ttagtttata tttcttaaat aagtttttta gttaaatttt
    94921 tcggtaaaga tgtataatat tttctgaaaa tttaaagaat tggggtatag attatggaaa
    94981 aacagcaaga caagggcttc ttcgggcagc cgaagggatt gtcaactttg ttcttcactg
    95041 agatgtggga acgatttagt tattacggta tgcgtgcatt acttatctat tatatgtacg
    95101 atacagttgc caacggggga cttggattac cacgagcaac agcattagct atcatgtcga
    95161 tctacggatc tttgatctac atgtctagta tcgtcggcgg atgggtatct gaccgagtgt
    95221 taggagcaaa acgcactgta ttcttcggtg gagttttcat tatgcttggc cacatcgtct
    95281 tggctttacc atttggtgta agtacattgt ttgtttcgat ggcattgatt attatcggaa
    95341 ccgccttttt gaaaccaaat gtttctggca tggtcggaca tctttattca aagactgact
    95401 tgcgaagaga tgcaggattt tcgatttttt acatgggtgt caacttaggg gcattattag
    95461 caccactaat cgttggtaca atcggtcaag aatataacta tcatttaggg ttctctttag
    95521 ctgctattgg gatgttcttt ggattattac aatacatcat ccaaggacgc aagacattag
    95581 acggagtggg tacaacaccg ccgaatcctt tgacaactga agaacgtaaa ggattcatcc
    95641 gtaacttgat catcgcactt gttgttatcg ctgcagtatt cggcggggca caactaactg
    95701 gtcatctgac aattgacttt tttgtcaata caatcagtgt attggggatt atcttaccgt
    95761 tgtattactt tatcaaaatg ctgacttcaa aagatgtaac tgctgaagaa aaaccaagag
    95821 tatgggctta tatcccatta ttccttgcag caatcatttt ctggtcatta caagaacaag
    95881 gttcatctat cttagcttta tttgctagtg aacgtacaca atctacgcta tttggtgtaa
    95941 cgatccaagc aagctggtat caatcattga atccaatttt catctttatt ctgacaccag
    96001 tattcgtaac gatgtggacg aaacttggtg aacgtcaacc atctacagta gtgaaattct
    96061 ctcttggact tttatttgca ggattatcgt acttgctatt gatgttgccg ggtatgcttt
    96121 atggtacaag tggaaaagta agtccattgt ggttgttggg aagtttcttc atcgtggtta
    96181 ttgctgaatt gtgtctttca ccagttggtt tgtctgtgac aacaaaatta gcaccacgag
    96241 catttgaatc acaaacaatc gctatttggt tcttagctga tgcttcttca caagcaatca
    96301 atgcacaaat tgcacgcttc tacacaccgg gaacagaatc tgcttacttc ggtattatcg
    96361 gtgcagtagc aatcgtcggt ggtatcttgc tatttactgt gaaagaacca atcaaaaaac
    96421 taatgggctc tattcattaa tcaatgaaca taaaaacagg aattgcttat ttgcagcagt
    96481 tcct
//
LOCUS       DASHXG010000005        82072 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.005, whole genome shotgun sequence.
ACCESSION   DASHXG010000005 DASHXG010000000
VERSION     DASHXG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 82072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.005"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(56..880)
                     /locus_tag="U2R59_000419"
     CDS             complement(56..880)
                     /locus_tag="U2R59_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8964843.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(853..1533)
                     /locus_tag="U2R59_000420"
     CDS             complement(853..1533)
                     /locus_tag="U2R59_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8964844.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1556..2494)
                     /locus_tag="U2R59_000421"
     CDS             complement(1556..2494)
                     /locus_tag="U2R59_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEM8964845.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2739..3602)
                     /locus_tag="U2R59_000422"
     CDS             complement(2739..3602)
                     /locus_tag="U2R59_000422"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEM8964846.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(3744..6317)
                     /gene="mprF"
                     /locus_tag="U2R59_000423"
     CDS             complement(3744..6317)
                     /gene="mprF"
                     /locus_tag="U2R59_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEM8964847.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFSEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6458..7264
                     /gene="proC"
                     /locus_tag="U2R59_000424"
     CDS             6458..7264
                     /gene="proC"
                     /locus_tag="U2R59_000424"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEM8964848.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7343..8899)
                     /gene="rny"
                     /locus_tag="U2R59_000425"
     CDS             complement(7343..8899)
                     /gene="rny"
                     /locus_tag="U2R59_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEM8964849.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9310..10359)
                     /gene="recA"
                     /locus_tag="U2R59_000426"
     CDS             complement(9310..10359)
                     /gene="recA"
                     /locus_tag="U2R59_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEM8964850.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10468..11709)
                     /locus_tag="U2R59_000427"
     CDS             complement(10468..11709)
                     /locus_tag="U2R59_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEM8964851.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11949..12527)
                     /gene="pgsA"
                     /locus_tag="U2R59_000428"
     CDS             complement(11949..12527)
                     /gene="pgsA"
                     /locus_tag="U2R59_000428"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEM8964852.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12736..13659)
                     /locus_tag="U2R59_000429"
     CDS             complement(12736..13659)
                     /locus_tag="U2R59_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964853.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(14398..15684)
                     /locus_tag="U2R59_000430"
     CDS             complement(14398..15684)
                     /locus_tag="U2R59_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEM8964854.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(15677..16945)
                     /locus_tag="U2R59_000431"
     CDS             complement(15677..16945)
                     /locus_tag="U2R59_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEM8964855.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            17197..17658
                     /gene="mscL"
                     /locus_tag="U2R59_000432"
     CDS             17197..17658
                     /gene="mscL"
                     /locus_tag="U2R59_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEM8964856.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(17717..18163)
                     /locus_tag="U2R59_000433"
     CDS             complement(17717..18163)
                     /locus_tag="U2R59_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8964857.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(18256..18501)
                     /locus_tag="U2R59_000434"
     CDS             complement(18256..18501)
                     /locus_tag="U2R59_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEM8964858.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(18616..19194)
                     /locus_tag="U2R59_000435"
     CDS             complement(18616..19194)
                     /locus_tag="U2R59_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8964859.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(19271..19801)
                     /locus_tag="U2R59_000436"
     CDS             complement(19271..19801)
                     /locus_tag="U2R59_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEM8964860.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(19805..20665)
                     /gene="rlmB"
                     /locus_tag="U2R59_000437"
     CDS             complement(19805..20665)
                     /gene="rlmB"
                     /locus_tag="U2R59_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEM8964861.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(20658..21053)
                     /locus_tag="U2R59_000438"
     CDS             complement(20658..21053)
                     /locus_tag="U2R59_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEM8964862.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(21050..22462)
                     /locus_tag="U2R59_000439"
     CDS             complement(21050..22462)
                     /locus_tag="U2R59_000439"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEM8964863.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(22459..22995)
                     /gene="cysE"
                     /locus_tag="U2R59_000440"
     CDS             complement(22459..22995)
                     /gene="cysE"
                     /locus_tag="U2R59_000440"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEM8964864.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(23081..23320)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23317..24777)
                     /locus_tag="U2R59_000441"
     CDS             complement(23317..24777)
                     /locus_tag="U2R59_000441"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEM8964865.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(24947..26104)
                     /locus_tag="U2R59_000442"
     CDS             complement(24947..26104)
                     /locus_tag="U2R59_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HEM8964866.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(26138..27508)
                     /gene="radA"
                     /locus_tag="U2R59_000443"
     CDS             complement(26138..27508)
                     /gene="radA"
                     /locus_tag="U2R59_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEM8964867.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(27571..28101)
                     /locus_tag="U2R59_000444"
     CDS             complement(27571..28101)
                     /locus_tag="U2R59_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEM8964868.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKASYMGEDEFLQLANRSSNPLKR
                     FLVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQ
                     DQTTAQRQGGFGSSSK"
     gene            28331..29137
                     /gene="proB"
                     /locus_tag="U2R59_000445"
     CDS             28331..29137
                     /gene="proB"
                     /locus_tag="U2R59_000445"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEM8964869.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            29134..30381
                     /locus_tag="U2R59_000446"
     CDS             29134..30381
                     /locus_tag="U2R59_000446"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEM8964870.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            30457..30801
                     /locus_tag="U2R59_000447"
     CDS             30457..30801
                     /locus_tag="U2R59_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964871.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(30918..31244)
                     /locus_tag="U2R59_000448"
     CDS             complement(30918..31244)
                     /locus_tag="U2R59_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964872.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(31859..33061)
                     /locus_tag="U2R59_000449"
     CDS             complement(31859..33061)
                     /locus_tag="U2R59_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8964873.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            33178..33693
                     /locus_tag="U2R59_000450"
     CDS             33178..33693
                     /locus_tag="U2R59_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8964874.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(33892..34338)
                     /locus_tag="U2R59_000451"
     CDS             complement(33892..34338)
                     /locus_tag="U2R59_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEM8964875.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(34385..35863)
                     /gene="msr(C)"
                     /locus_tag="U2R59_000452"
     CDS             complement(34385..35863)
                     /gene="msr(C)"
                     /locus_tag="U2R59_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEM8964876.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(36217..36846)
                     /locus_tag="U2R59_000453"
     CDS             complement(36217..36846)
                     /locus_tag="U2R59_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEM8964877.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(36830..37294)
                     /locus_tag="U2R59_000454"
     CDS             complement(36830..37294)
                     /locus_tag="U2R59_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8964878.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(37781..39049)
                     /locus_tag="U2R59_000455"
     CDS             complement(37781..39049)
                     /locus_tag="U2R59_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEM8964879.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(39280..40017)
                     /locus_tag="U2R59_000456"
     CDS             complement(39280..40017)
                     /locus_tag="U2R59_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8964880.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(40084..40653)
                     /locus_tag="U2R59_000457"
     CDS             complement(40084..40653)
                     /locus_tag="U2R59_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEM8964881.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            40781..41653
                     /locus_tag="U2R59_000458"
     CDS             40781..41653
                     /locus_tag="U2R59_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8964882.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            41995..42867
                     /locus_tag="U2R59_000459"
     CDS             41995..42867
                     /locus_tag="U2R59_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8964883.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            42864..44822
                     /locus_tag="U2R59_000460"
     CDS             42864..44822
                     /locus_tag="U2R59_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8964884.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(45154..46005)
                     /locus_tag="U2R59_000461"
     CDS             complement(45154..46005)
                     /locus_tag="U2R59_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8964885.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            46128..46595
                     /locus_tag="U2R59_000462"
     CDS             46128..46595
                     /locus_tag="U2R59_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEM8964886.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(46858..47340)
                     /locus_tag="U2R59_000463"
     CDS             complement(46858..47340)
                     /locus_tag="U2R59_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HEM8964887.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(47440..48303)
                     /locus_tag="U2R59_000464"
     CDS             complement(47440..48303)
                     /locus_tag="U2R59_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEM8964888.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            48901..49776
                     /locus_tag="U2R59_000465"
     CDS             48901..49776
                     /locus_tag="U2R59_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964889.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(49921..50073)
                     /locus_tag="U2R59_000466"
                     /pseudo
     CDS             complement(49921..50073)
                     /locus_tag="U2R59_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(50341..51672)
                     /locus_tag="U2R59_000467"
     CDS             complement(50341..51672)
                     /locus_tag="U2R59_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8964890.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(51821..52534)
                     /locus_tag="U2R59_000468"
     CDS             complement(51821..52534)
                     /locus_tag="U2R59_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8964891.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            52709..54133
                     /locus_tag="U2R59_000469"
     CDS             52709..54133
                     /locus_tag="U2R59_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8964892.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            54432..55139
                     /locus_tag="U2R59_000470"
     CDS             54432..55139
                     /locus_tag="U2R59_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEM8964893.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            55126..55449
                     /locus_tag="U2R59_000471"
     CDS             55126..55449
                     /locus_tag="U2R59_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEM8964894.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(55538..56575)
                     /locus_tag="U2R59_000472"
     CDS             complement(55538..56575)
                     /locus_tag="U2R59_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8964895.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(56896..57879)
                     /locus_tag="U2R59_000473"
     CDS             complement(56896..57879)
                     /locus_tag="U2R59_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HEM8964896.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(58294..59064)
                     /locus_tag="U2R59_000474"
     CDS             complement(58294..59064)
                     /locus_tag="U2R59_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964897.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(59057..59992)
                     /locus_tag="U2R59_000475"
     CDS             complement(59057..59992)
                     /locus_tag="U2R59_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964898.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(60308..61957)
                     /locus_tag="U2R59_000476"
     CDS             complement(60308..61957)
                     /locus_tag="U2R59_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEM8964899.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(62074..64677)
                     /locus_tag="U2R59_000477"
     CDS             complement(62074..64677)
                     /locus_tag="U2R59_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEM8964900.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(64689..65738)
                     /locus_tag="U2R59_000478"
     CDS             complement(64689..65738)
                     /locus_tag="U2R59_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEM8964901.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(65764..66078)
                     /locus_tag="U2R59_000479"
     CDS             complement(65764..66078)
                     /locus_tag="U2R59_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEM8964902.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(66094..66540)
                     /locus_tag="U2R59_000480"
     CDS             complement(66094..66540)
                     /locus_tag="U2R59_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8964903.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(66541..68463)
                     /locus_tag="U2R59_000481"
     CDS             complement(66541..68463)
                     /locus_tag="U2R59_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEM8964904.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(68675..69571)
                     /locus_tag="U2R59_000482"
     CDS             complement(68675..69571)
                     /locus_tag="U2R59_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8964905.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(69564..70244)
                     /locus_tag="U2R59_000483"
     CDS             complement(69564..70244)
                     /locus_tag="U2R59_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8964906.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(70245..71027)
                     /locus_tag="U2R59_000484"
     CDS             complement(70245..71027)
                     /locus_tag="U2R59_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964907.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(71020..71937)
                     /locus_tag="U2R59_000485"
     CDS             complement(71020..71937)
                     /locus_tag="U2R59_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8964908.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(72101..72424)
                     /locus_tag="U2R59_000486"
     CDS             complement(72101..72424)
                     /locus_tag="U2R59_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964909.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            73212..76439
                     /gene="fss3"
                     /locus_tag="U2R59_000487"
     CDS             73212..76439
                     /gene="fss3"
                     /locus_tag="U2R59_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEM8964910.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            76552..76866
                     /locus_tag="U2R59_000488"
     CDS             76552..76866
                     /locus_tag="U2R59_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8964911.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            76879..77253
                     /locus_tag="U2R59_000489"
     CDS             76879..77253
                     /locus_tag="U2R59_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8964912.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            77263..77598
                     /locus_tag="U2R59_000490"
     CDS             77263..77598
                     /locus_tag="U2R59_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HEM8964913.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            77681..79021
                     /locus_tag="U2R59_000491"
     CDS             77681..79021
                     /locus_tag="U2R59_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEM8964914.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            79099..79773
                     /locus_tag="U2R59_000492"
     CDS             79099..79773
                     /locus_tag="U2R59_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8964915.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            79766..79930
                     /locus_tag="U2R59_000493"
     CDS             79766..79930
                     /locus_tag="U2R59_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964916.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            80006..81148
                     /gene="dcm"
                     /locus_tag="U2R59_000494"
                     /pseudo
     CDS             80006..81148
                     /gene="dcm"
                     /locus_tag="U2R59_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            81138..81428
                     /locus_tag="U2R59_000495"
     CDS             81138..81428
                     /locus_tag="U2R59_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964917.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            81687..>82072
                     /locus_tag="U2R59_000496"
     CDS             81687..>82072
                     /locus_tag="U2R59_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964918.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGV"
BASE COUNT        24306 a        16885 c        14710 g        26171 t
ORIGIN      
        1 aaaaagaagc ctataaaaaa tttttcgttt ttataaggct tcttttcttt ataatttagt
       61 tattttttct tctgaaggca accaatattc gtttgatgat atttacaatc aggaacaaag
      121 caataaagac taatgtgatt gttgctcctg gaggtgtatc tagataaaac gagctagtta
      181 gtcctgacag catccctaga aatcctacac aaacactgat agcaatcacg acattgaagc
      241 ttttgcctaa tcgcataccg attgctgcgg gaagaaccat gattgcggat atcaaaagtg
      301 caccggcaat cgggatcatc acagcaatag ccacaccagt aatcacattg aacatcatcg
      361 acatcaaatg aacgggtagc ccatccacgt gggcggtatc ttcatcaaaa gtcagaacat
      421 acatcggccg tttgaataaa aagaacaata taccgatggc aacgaataag attcctaaaa
      481 agatgacttg ctcccatgta atggtcacga tcgaaccaaa cagataggat tggatacttg
      541 ttgctgaatt ccctccgctc aaattcatca atactaacgc tagcgccaaa ccaccagcca
      601 ttaaaatggc aatggagatt tctgaatagg ttcggtagat cgttcgcaga tactccaata
      661 tcacagctgc taatacaacg actagcatgg tcgtaagtgt aggattaagg ttcaaaaaga
      721 atcctaacgc tacccctgct aaagagacat gagaaagcgt atcagccatc agcgattgtc
      781 ttctgatcac taaaaacaca cctagcatcg gggcgattcc ggcaatgaag atagcggcaa
      841 gaaacgctct tctcatgaat tcatatgaaa gcaacgccat tgagaatcct cctttctcac
      901 cagtcggatc tgtctgtccg catactgttt gatatcttca tgatcatggg tgatcattag
      961 aactgatttc ccatggacat gcgcactatg tcggagaaga cgataaaatt catttctgga
     1021 ttcttcatcc atacctgttg ttggttcatc aagaacaaat aagtcagggt cagtagcaaa
     1081 aatacgcgct aaactgattc gctgcttttg tccgccagac aattcaccta ttcgccgatt
     1141 tcgcatatcc cacatcccta cagcttctaa agcacgctgt acatgttgat gatctttttc
     1201 agagagacgc ttgaaccagc ggcctcttgg atatcttcct gaacggacta attcgatcac
     1261 cgtactagga aaacctgcat tgaaagatgc aacttgttga ggaatataac cgatacttaa
     1321 tttttttcct tcttgatttt tctcagcaat ctttatcatt ccttttgaag gtttcagtaa
     1381 tcctaacgat gctttcacca aggttgactt ggctgctcca ttttctccag ttaaaatgac
     1441 aaattcaccc gcatctacat gataagagac atcttctagt acaggttcat catcatagta
     1501 aaaggtcaaa tcagatattt cgatataacg caccttacaa cctccattct aaaacttaat
     1561 tgatactttc ttttaaagct ttcagatttt tttccatgac agaaatataa ttttcgcctg
     1621 ctttgatttg ttcattagtc aagctttcta aaggattcaa cacttctagc ttcactcctg
     1681 tttcattcga caatgtctca gctaccttcg aagaggcatt ttcttcaaaa taaatcactt
     1741 tgatgttgtt tttcttcaca aattctttta gctcagctaa gcgacttggt gtgggttcct
     1801 gatctggtga aacgcccgaa atcgctactt gttttaagtc gtattgattc gctaaataag
     1861 caaaagcagc atgctgagtg acaaatgtgc ggtttgttgc atcttttagc tcatcggagt
     1921 atttttgatc cagtgcttca agctttttga tataagcatc ggcattcttc gtaaaagttt
     1981 cctttttatc tggatatttt tcgcctaatt cttcagcaat cgttctgact tcttttatag
     2041 ctaataccgg atcgagccaa acatgtggat cgtattcatg tgaatgacca tgcccttctt
     2101 ctgattcttc atgttcgtct gcttcttgcg attctaaacg gtcgattcct ttagctgctt
     2161 cgatcatcaa ggtctgtttg ctatccactg aatcctttaa cgaatccaca aaaaattcca
     2221 tgtctgaact attatacacg aaaacatctg catcggaaat ttctgctctt tcttttgcac
     2281 ttggttcgaa atcatgcggc tccgttccag cagggatcaa aagtttcacg tttccttcat
     2341 cccctacgat ctcttttgta aaatcataca tcggataaaa agtcgtaacg atcgtcaaat
     2401 cctctttttt gtctgcttcc ttgttcgtat ttccacatgc tgcaaacagt aaagcaccta
     2461 tcattaccgt agctgtcaaa agatattttt tcatttatat gctcctttca atgaacaaat
     2521 cggaatttta cgatttatta acgtgaacta atgtatcaaa ataaaaaaac acagtcaata
     2581 gaaatccatc aatttctgat ttaagcatgt atattcttga ttaaatcgta aaatggatga
     2641 gttgctgctc atatctagcc atttcactac aataaaaaac tgaagaatac cattttagga
     2701 ttcctcagtt tttcatcacc tattttactt cttatatttt attgcagggt tcgtactaaa
     2761 taaacttcct cacaaaaacc ttttaaccca ttatatactc tctgcgctct tgaataatgt
     2821 tgacacaagg caaaaacggt tggtccgctt ccactcatca atgcagcatc tgctccgtac
     2881 ttgatcatac gctctttgat ttgatggatg actggatgcc gctttcccgt tatatcttct
     2941 aaactgtttc ccattttttt gatcatctgc tgataatctt gctctcggat ggcttcagca
     3001 agtccgtgga tgtcttgatg ttggatggct tgcgtatcta cttctctaaa cactgtacgt
     3061 gtagagacac tcattcttgg tttgaccaac acaacccagc actgtggcat agaaggtaat
     3121 acttggattt cttccccttt gccaccgaca aatgccgtac ttccgtagac acagtaagga
     3181 acatctgtac cgacttccaa accgatttct gccagttctt ctaacgaaca gcccagattc
     3241 cataattggt tgatccctct tagagcagct gcacagtctg tacttcctcc gcctaatcca
     3301 gctgctactg gaatattctt cttaacaaag atcttgacac cggttttgat attgtattta
     3361 ttttttagca ataaagcagc ttgataaaca ttgttccgtt catctaccgg taaaaatgct
     3421 ttatttgttt ctacaatgat tttgtcttct gttatttctt caaaaaatag atgatctgcc
     3481 aagtctacgc tcgacatcac catttccaac tcatgatacc catcttgccg tctatataat
     3541 acatccagtc ctaaatttat cttggctggc gctttttcaa tcaattccat cctctcaccc
     3601 attcgaaaag tctaagtcgc aagtattcta tcatagggaa aaataaaagt atagcttatg
     3661 tctgcctagt ggttgatttt gtcatcgttt caacagcttt cacagaattt tctcttcata
     3721 atccaaacaa gttctagtga ttcttataat tctgtgagca cttcttctgc caaactcgga
     3781 acatttcctt tttcttttcc tatcagactg agtagctgca tggtagcaaa tccgaaatta
     3841 cttcctttcc tataagcaaa gtaacgtcct tcccaatgat cgacatattt taatttcttt
     3901 tcataagcag actggaagga atagaaaaaa ttaccataat tatatacgat atgcatgact
     3961 ttttcttgaa agaaagaaaa atctgtttct ccaacattag ctaatggagc taagcctaga
     4021 ttggcttccg agtagcccat tttctcgtat acaataaaca gattggctaa cagatagtca
     4081 gctaattcct cagattcttt aggtaagacc cgcaacaaat catatcccgc ctgcttcttc
     4141 gtcatcggct gagcggtgat gaagccaacg actttttgat ctttacggac aataccgaca
     4201 ccgctagata atacatatga tttatcaaat cgtcccacag agaagtattt ttctcgtgca
     4261 ccttgaagcc atttttgtga aacttcattt acagcttgat gtaattcttc tggcagttga
     4321 tcgtaccaag taaaatggta tccttctttc atcaaacgtt gatattcaag ttgctgactc
     4381 agccgagaca agtcttctgt tgctagatca acaatccctg cttcacctac tttcgtgaag
     4441 tgaaaaccca attcatgaag catcactacg tagctttctg atatcttata aaacgcaagc
     4501 tgatagccta aacaatctgc ttgtttcata aactgattcg ttgctgcccg catcatttta
     4561 ggatttccaa ctggatctcc taaaacaaag catttgtttc ctttgatctg ataaccaaaa
     4621 acgacttgat cttggtcatc ttcttggtaa taaaaataac tgtaacctga caagcgaagc
     4681 tgatggcttg tagctgtgcc tccgtatgtt tccaataaac ggtcaaaacg gtctttttcg
     4741 tactcactgc caagcttcgt agtatcttca gctaaatatt gataaagcgc cactaaagct
     4801 agcaatgaga tgcccaaacc aataagccct gagaaccaca catcatctga aggaaacaaa
     4861 ataaaatggt ttcctgttat tcgaccgact aaaaagcgtc cgctgtgata gcctgcaatt
     4921 gcgtaaacga taaacaaaaa gccgaacaag ctagcatcaa agattatagc tccccaagaa
     4981 taaacgaatt ttgttcgata aaattctttt ctggataacc acacagctaa cagaatcaag
     5041 acatatacca atatcaactg ccaagataac gtacgtgtga ttgtatttaa aataccaaaa
     5101 gatagtaaag caatcgtagg cagaaatgcc tttttgactt ttactgaaag tgctctagca
     5161 aggccgagta ataaaaagcc aaccaataga ttcactgtct gatctaaaaa attgaatgag
     5221 aacggcaata atacttgaaa tagccgactg attgcagaca gattagtgat tgttgataga
     5281 agtaccatca tgattcccgc aaaatagaca gcacttacga gcacgatatg cgcaaccttt
     5341 tggaaaaaca gtcgcggaat gttatctaaa aatcgattga ttttgactcc tgtatgtgtg
     5401 atgaacaata gaagtcccgt cataaaaggt agaacataat aaaacaaccg ataatataat
     5461 agccaaacta ctgctacatc ttgccgaaca gacaattgac tcattcctaa gatcatcaaa
     5521 acgtcaaaag tccccattcc ccctgggacc atcgtcagca ttcctatcaa tgtagcaatc
     5581 atgaacatag gatagatcga aagcatcgaa atatctattc tcatcaactt gccgatgatc
     5641 aaaaataccg caagggctcc cgtccattgt ccaaaggatg ccagtagcag accaagcaag
     5701 ccttttggat aaaactcaga gaacaaggtc tttctcttta gataagcaaa aaagaaaatg
     5761 actggtgcta aaaaactacc gccgaaaagc cagatccaat agcttcgaaa aatactttct
     5821 gactgaataa aaaagacatc aataaatgta agaaacgacc atacagacaa accagtcagc
     5881 ataaatagtg cgacttttga tacagtggct aaaaccattt ttctatttgt ctgctttcca
     5941 taaaaactag ctcgcaggct tgctcctacc acaccaccaa aaccggcgag attgttgatc
     6001 gtgtttgtta cccacgcagc aagaagaaac tcttttcttt ccatttttgg ttttccttgt
     6061 ttttctaaga ctctgatcgt cacccaatca tacaacaaca tcggagtgac acccagcagt
     6121 ccagccagaa tcatgagcag gatcgtcatg cggctttgtt gtcccatcct ttgccaaata
     6181 tcttgccaac tcatgccatt agcaatattt gcgacttgat ttgccacaaa gactaacacg
     6241 gagccgaaaa aaatcagttt taaaatcaga ctatgttcct ttatccattg cagcatcaag
     6301 tatcgtttat ttttcacatt ttcccattcc taacttgtat acttttgtgt cataccccaa
     6361 tgttatctta tttattttaa tttttccact ttagacctgt tctttgcttg cgatgataga
     6421 aaaagaaaga tatcctaatg ctaaaggaga ggataacatg aaagtaggat ttatcggcac
     6481 agggaatatg gcacaagcta ttattgatgg tttattaaaa aaaggaacag tctcgaaaga
     6541 agaggtgttc gtttccagtg gacattttga aaatgcacaa aaatttgctg ctgaaactgg
     6601 cgtccatgca tgcaaaagta atcaggaagt tgcatcacaa tcagatatcg ttcttttagc
     6661 cgtgaaacca aaaatcattg aaaaagtatt ggaagaacta agagaatata gccagaaagt
     6721 cttattcatt tctattgctt caggaaaatc attaatagat ttagaaacag cgcttgaaga
     6781 tcctcaggcc tccatcgtac gtgtgatgcc gaatgtcaat gtcagcgtag gagcaggcgt
     6841 ttctgcgatt tgcaaaaatg aagctgccac ggaggaacag cttcagcaag ctacgatgat
     6901 ttttgaagca atcggcagcg tctatccttt agcagaatca gatttcagta cattcattgg
     6961 ccttgctggc agctcacccg cattcgttta catgctgatc gatgcgatgg gacggactgg
     7021 tgtactgaat ggtttgtcca aacagacagc cactgagatt gctgcaaaag caattatggg
     7081 ttcttgtcaa aaattccttt caagtgataa aaatccatgg gaacttgtag accaagtttc
     7141 ttctcctggc ggtacaactg ttgcaggtgt agttgcctta gaagaagcag gattcatccc
     7201 agcaatcatc aaaggaatca atacgacgat cgagaaagat cttgagatgt tgaataaaaa
     7261 ataatgatag caatgttttt tcgtgcctta caaaaaaaga agagctgtgg cttttgccgc
     7321 ggctcttctt ttgtattttt tattatttag cataatcagt tgcacgagtt tcccgaataa
     7381 cgattacttt gatgtgtcca ggataatcca gttcttcttc gattcgttta cgaatatcac
     7441 gtactaaacg aacagcgtct aaatccgaga tttcttctgg cttgaccatt acccgaactt
     7501 cgcgtccagc ttgaactgcg taacttgatt ctacaccggc gaagctgttc gaaatatttt
     7561 ccagacttct taaacgacgg atgtagtttt ctaatgattc acttcgcgca ccaggtcttg
     7621 ctgctgagag cgcatctgct gcagctacaa ggacagagat aacagaagta gcttccacat
     7681 ctccatgatg agaagcgatc gcgttgatta ctactgggtt ttctttgtac ttggcagcta
     7741 attccgcacc gatctcaacg tgagatcctt caatctcatg gtcaagtgct ttcccaatat
     7801 catggagcaa cccggcacgt tttgctaatt ggatatcttc gccaagctct gctgctaaga
     7861 taccagctaa ttttgcaacc tcgaccgaat gcttcaagac gttttgtcca taactagttc
     7921 tgaatcgcag acgtccgatg atcttgatta gatctggatg aagtgtatga gcaccgactt
     7981 caaacgctgc ctcttccccg tattcgcgaa tacgttcatc catttcttta cgagatttct
     8041 cgaccatttc ttcgatacgc gctggatgga ttcgtccatc ttgtatcagt ttttccaagg
     8101 tcatccgtgc gatttctctt cggattggat cgaatccgga aagaacaact gcttccggtg
     8161 tatcatcgat gattaaatcg ataccagtca gcgtctcaag cgttcgaata ttacgacctt
     8221 ctcgtccaat gatacgacct ttcatttcat cattcggaag ggtaacgact gaaacagtcg
     8281 tttctgaaac ttgatctgct gcgcagcgtt gaatcgctaa tgataataag tttttcgctt
     8341 tgcgatctgc ttcttctttg gcacgctgtt cagattcttt taccattaga gttaactcat
     8401 gattcagctc ttcttcagtc gatttcatga tgacatctcg tgcgtcctct tttgataaac
     8461 cagcaatttt ttctagttct ttttgttgat cttcaatcat tttttcaacg tctttttctc
     8521 gctcttcaat taattgctgt tttgaactaa gtgcttcttc tttactttca agtgagttct
     8581 cgcgtttttc taacgagtca tctttacgat tcagcgtttg ttcgcgttga atcaaacgat
     8641 tctcttgaga ttttaattct aacttacttt ctctcagctc actttcaact tcagaacggt
     8701 atttctgatt ttcttcctta gcttctaaca atgcttcttt ttttagagtt tctgcttctt
     8761 tttttgcact atcgatgatt ccagcagctg atgattgtgc accagctatt tctttctcgt
     8821 gacgtgactt tgcgaccata aaccctaaac caagaccgac aattaaaccg atgatagcga
     8881 ggagaatgtt gaataccata aaatccacct ccatactatc tttttcattt ttatcatcta
     8941 tacagcttct atgataaatt attctaaact cgtcaatatg catcttcgca tatatgtgta
     9001 caaaaaacat gcacaacttt attctaatgt ttgtaccccg tagtgtcaac tttaaataaa
     9061 caaagaaacg gctttctact tattcattaa acgatggttt ttaaaataaa tgacactagt
     9121 ttcatatagg taaaccttta aattgagaaa cttttctatt aaattattct ttgtagatga
     9181 acagatattt ttattttatg tacccactcg tataattaaa taactcacga tttctttatt
     9241 caataaaaaa acggcaggtc aaggagagta cctactcttc agaccagccg tttttgttta
     9301 tcataatttt tattcttcta ctaaaggcaa ttcttcttgt cctttttcat cttctgggac
     9361 agcgacttct tcaccaatac cataagctgc tctaactaga gcagaaactt ctgccatcat
     9421 ttcaggatga ttagccatat agattttagc gttttcccgt ccttgaccaa tccgatcttc
     9481 tttataagaa taccaagcac cgcttttatc aacaatgtct ttttctactg ccatgtctag
     9541 aagttctcct tcttgtgaga tccctaaacc atacatgaca tctacttcag cgattttgaa
     9601 aggaggtgct actttgtttt ttacgacttt gatctttgta cggttaccaa caatatctgt
     9661 accttgtttc aattgttctg cacgacgtac ttccaaacgg atcgttgcgt agaatttcaa
     9721 tgcgcgtcct ccaggagtga tttctggatt cccaaacatc acgcctactt tttcacggat
     9781 ttggttgatg aaaatagcga ttgtttttgt tttgttgatc gaaccagaga gtttacgcaa
     9841 tgcttgagac atcaaacgtg cttgtaaccc gacatgtgag tcacccattt cgccgtcgat
     9901 ttctgctcgt ggaactaaag cagcaactga atcgactact acgatatcta cagccccact
     9961 tgatactaaa gcatcagcga tctctagacc ttgttctcct gtgtcaggct gtgaaagaag
    10021 tagttcatcg atattcacac ctaatttttg tgcatattgc ggatctaacg catgctcagc
    10081 atcaatgaaa gcggccgttc cgccattttt ttgtacttct gcaatagcgt gtagtgcaac
    10141 tgttgtttta cctgaacttt caggtccata tacttcgatg atacgtccac gggggtaacc
    10201 gccgacacct aaagcgacat ctaacgcaag agagccactt ggaattgtag agatttgttg
    10261 gtcgattttt tcgcccaatt tcataataga gcctttacca tagctctttt caattttttt
    10321 cagtgcagca tctaaggctg ctttacgatc atctgccaat acgataatcc tccttatatt
    10381 tacaaatcag agcaacattt cattatcctt atcatatctt ttttagtgaa aaaaagcaag
    10441 aaaaaaccga acaaatattc gcatttatca ttttcttaaa agctgttttc tcaaaagatc
    10501 aaatccttgc ataaccgcat tatatctgat agcagcacga tctctggcaa agtgatattt
    10561 ttccgaaacc acgccgtctt tagatgaaat agcgatccat actgttcctg cagattgacc
    10621 ttctaacgtg tccggtccag ccactccggt gaaagctaca ctgtaatctg ttcttgctat
    10681 ctcacgtgct tgaatggcca tctgctccac acattctttg ctgactgttc catattctgc
    10741 taatagctcc ggatcaatct ccagaaaacc agcttttgtt tggagcgagt aggtaacgaa
    10801 tccgcctgga aatacttcag atacaccagc aatgtcgcct aatgcggctt ggaaggcgcc
    10861 ggctgtcaaa ctttccgctg ctgttacagt ctgcttgttt tctttcagta gttccactac
    10921 gacttttgct agcgaattat catcgccgta tccataaaaa tattccccta ctcgttcttg
    10981 gattttttct tctaatgcta aaagagcttg attccctgcc tgaacatcat ttgttttcac
    11041 tgtcagtcgt aatgtcactt catttggttt ggcatatggt gcgatcgttg gattgatctg
    11101 tgtctcaatc agatctttta gctcagtgac cagtcgcgat tcaccaatcc cataaaagcg
    11161 caaaacttta gaaattagtt tttcttcaga aggaaaacgt tcctctagta aaggacgtac
    11221 ttgttccaca aacattggtt tcaactcatt aggcggaccg ggaagaagga tatacgcatg
    11281 tgtatctgtt tgataaaaag tccctaaagc aagccctgta cgatttggta gaggaacccc
    11341 gccttcgata atctgggact gttgcagatt gtttttggtc atttttcgat gggttgtttc
    11401 aaaatatgcc aataattttt tgtatccttc cgtattttgt atgagagact taccgaggtg
    11461 agccgcagtt gcttcttttg tcaggtcatc ttctgtcggt cctaatccgc cacataagag
    11521 tatgagttca cttcttgttt cagctagagc aatcaactct tctaaacgct gctgattatc
    11581 tcctacaact gtttgataat aaacttcgat acctagatca gctagctgtt ctgacaagaa
    11641 agtggcattc gtattcacga cttgtcctag taaaagttct gttccgacag ctattatttc
    11701 tgctttcatt acttcccgct cccttatata gtatacgctg tatttttata tttttttatt
    11761 taaaaagagg gcaaggagct gtgacaaaaa tcttgtcaca gctccttgtt ccaaataaac
    11821 agtgttctcc tgccaaaacc tcggtcataa gtcacaatat acataaaaca tgaaaagctg
    11881 ttttttgaaa ttatcccttg tgactcagag ttagacggca ggctcacaac ctctccacta
    11941 aacgatactt acattgatcc tttgaacaca ccgctgtttt tgatgaagta atccacacct
    12001 gaatagatag taaagatcag acaagcataa agcatgattt gatctactgg aataccgatc
    12061 aggctgaatg ggatattatt gataaacagc aagataatag caaccatttg tgtagccgtc
    12121 ttgacttttc ccggccaagc tgcagccatg acttctccat gttcgacaag tagtaaacgc
    12181 aagcctgtga cggctaattc acgacagaca atgatcgcta ctacccaacc aggggccttt
    12241 ccttggtcaa ccaacatgat aaaagcagtc ataactagca ttttatctgc caacgggtcc
    12301 gcaaacttgc caaaattagt gacaaggcct cgcgcacggg caatttttcc atctaaccag
    12361 tctgtgatac tagctaaagc aaaaataact gcacctacta gctgtgtgac agccagtgtg
    12421 gtgtctccta cgttaaattg tccccaatct aaaggtaaac ctacaaccaa aatgaaaatc
    12481 gggatcatac aaattctaag tacagttaat ttatttggta aattcacact atcgactcct
    12541 ttcttcccta ttctacgtga ctatcagcga agtttccacc gatattattt acttttccaa
    12601 atgaatttat tcaaaggagt atttttattg aaattgatct ttttgaatta acgaagaagg
    12661 accgcgacac agatttgtca cgatccttct tttttatacc tacaagtaaa cagatgcgta
    12721 aactaattta tacgatcatt ctgcgtattg aagagtaagg ttcacatttt ttggactctg
    12781 attgttttcc cctggattaa ctggtacgga ttctccattc gctttgatcg ttgcattgct
    12841 tgctgcacca atcgtgatgg tcgcatttgt tgctgtttcc ggtaacacgg tactctgtgt
    12901 ttcatttgct gccagtgtcc cttgataaac ataggcattg tctactagca cacctaacca
    12961 tacacgattg acagcagtaa attcaagggt tacaggcttg gtagcgtctg tgatatttac
    13021 tgcgatggca ctgccagaat cttctcctgt agctattgcc attttctttt cttcacttga
    13081 ttttgttgtt gattctactg tagaagactc tttggtctgc gtgctttgct ctgaggaaga
    13141 ggactcctcg actgatcctt ctactttaag cgaagaagct gtgtctccga ttattggatc
    13201 agcttgacga tcttgccaag tcatatagcc cacgacaacg acaatcgcca aagcaaccaa
    13261 tcctaataaa atgacaggaa gacttgtcca aaagcgactt ggatgcgatt cttcctgatg
    13321 cattgctttt ctagaagtac ttactgtttc aggctgcgga cgttcaggga ccgatcctgt
    13381 caatttgctt ttcccatcaa aaacatcgac taaatggtct ccatcttctc ctacagcttc
    13441 agcgtattgc cgaataaatg cccgcacgta aaatttacca ggcaattggt caaaatcatc
    13501 attgtcgatt gcttccaaat aacgtttttg aatttttgta atctgctgta attcatctaa
    13561 agatattttt ttattcaggc gtgcttgccg taatttttct ccgatggttt caaaagccac
    13621 tcgttcatct tctccagtct gtttgattct ccgaagcatc tgctgttgca acgaaagacg
    13681 ttatgtttgg gtgctgtgac aaaagtcatg tcacagctcc ttttttccga ataaacattg
    13741 ttctcctgcc aactcctcgg tcacaagtca caatatccaa taaatataag aagctgtttt
    13801 ttgaacttgt tccttgtgac tcggagttaa acggcaggct cacgacctct ttcttaaacg
    13861 gtgttcaatc agctgttcct cggtattagc tcaaaaaccg gcaaaatata aggagatatt
    13921 tttccgtatg tttctctaat actcaggtca aaacgctgat ttcacaacct cttccttaaa
    13981 cggtgttcaa aagcttgcat ctgcggtaat aagtccaacc aagttaaaaa cattaagaag
    14041 ctgtttttac ttggctgttc ttattacttg atgcagggca gctttttcac aacctcttgg
    14101 tacacggtgt tccagaagta gcttcttcgg caataagccg aaatatcaca aaaatttgag
    14161 aagcaatttt cgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctct
    14221 ttgattactt cgtttgattt tattttaata taagttgatt aaaagagagc atgatttgtt
    14281 ttattttctc actaattttt ccaacacaac taagaatacc ataaaagctg attttggagg
    14341 aggttcctac tacaagtcta aaacgaaatt taagactttt cctcataaaa tactggttta
    14401 ttttggtctc atgtaaaact cgctgaaggc ctcttcactt ataaatgctt ccccagctgc
    14461 cagtacgtct ttcatttgga tcgaatcgat gatttcagga agatcaaata aagttcgatc
    14521 gccaaataaa ctttgcgtaa attgattggc aatatattcg atcgaattta atgattggaa
    14581 atattgtcca agcattttct tcttcagcaa atcgagattt gtttctgaca cttccggatc
    14641 atcagcgaat ccaagaatga tttctttgac tttttctgct gctttctctg gttcgtccgt
    14701 atctccgctg aagtccgcaa agtgaaattc acgatccaag ctgaattcaa aaccaaagct
    14761 gtcatcgata attccttgat tgtacatcgc tagatagttt cgagaagtat tgcctaaaat
    14821 catttggaac aacagattga ttgctgtttt atagcgtaac agttctgttc cttcttgcgg
    14881 caatgtgtct aatcctttaa taccaagtac aaatttatct cgtgtaatgg ctgcttccaa
    14941 tgcactttgt ttgatgattt cttttgtgtt ttcagggaaa taacgtacaa tttcttgctt
    15001 tggagggaaa ttttttgctt cttggttttc ccgaataagt ttcatcaatt tctcaggctc
    15061 catcttacca actacaaata aaaccatatt gcttggctga taaaacgtcc gatagcacgt
    15121 atacaagtct tgagctgtga ttttgtcgat actttcaacc gtgcccgcaa tatcgatatg
    15181 caatgggtgt gtaggataca agttatttag tatgccaaaa aacatccgcc agttagggtc
    15241 gtcttcatac atttggattt cctgaccgat gattcctttt tccttgttta cagtttcttc
    15301 tgtgaagtaa ggtgcttgta caaaatcgat cagagtcgtc agattctttt ctacctgatc
    15361 cgtcgtagaa aacagatagc tggttttcgt aaaacttgtg aaagcattgg cggaagctcc
    15421 ttgtttccca aataattgaa agacatcacc atcttctttt tcaaacaact tatgttctaa
    15481 aaaatgggca attccatctg gaactttcac cttttctttt tcaccatagg gaataaattc
    15541 gttatcgatc gaaccataat tcgtactgaa caaaccatat gtcttgtgat agtcattttt
    15601 aggcaacaaa tacacggtca aaccgtttgg cagtacttca tgataaagtg tttcattgat
    15661 ttgctcatat tctgttttat tcatttgcat ttcctcctgc taaaaagaag attgcctgca
    15721 attcgatttg ctcagctact tgttgtatct ctttgatcgt tacgctctcc atacgtttca
    15781 accattcttc atcagataat tttgtttccg gcagccagct gtccaaaaaa gaagcttcga
    15841 ttgccgcttg cggagagtct agagaaagca gatattggtt tctcagcatt gcttttgtct
    15901 gagacagttc caactctgtt atttcaccat ttcgcaaact ttctaattgc tcgtgaatca
    15961 gatgaagtac ttgatttcgg ttcttttcat cgataccggt ttggacactc atgaatcctc
    16021 ggaacgtatc cacgctacta gaggcataat aagctagact ttctttctct ctgacattca
    16081 tgaaaagttt agagtgagga aaaccgccaa ataaaccgtt aaagaccatt agcgcaaaac
    16141 gttctggttc atcgtaatac acatttgtct gataagctag gttcagcttt gcttgaacga
    16201 ttggctcacg tacttgtcgt tccttcacga tattcacttg aggttgggta taaaacagat
    16261 ctggataaac tgtttcccgc gactcaaatg gtaattgccc aactgcttca gctgctttgt
    16321 ccggatcaac atcgccgaca acaaaaatgt cgatttgatc atttgccatc atttcttgat
    16381 agtaggacgc tagcgaacta gcagtgatct tgtccaaatc ttcgactacg cccaaccctg
    16441 ggatcttttg ttccgggctg ttttcaaaat aaagttcttg caaggcatag gaagcaaaag
    16501 tttgtttatc ttccttcaaa ctttccaaat atagacgcag attgttcttt tccaagtcaa
    16561 acgtcaactg atcaaactga tgatttttaa tatttggata aaataaaacc tcttttaaaa
    16621 aatctaccgc ttgagaaaaa aggtttggat cattgacata ttcaccattc acaaaactga
    16681 tccctgcgtt tagccaatgt aaatttcctt tttttctaac tgataatcca aagcttgcgc
    16741 cataaagctc tgcaagttgc gcacttaact ttgtctgatc cgaataattc aaactatttg
    16801 tttccaacat gctgctgaga agtgaacgtt tcgtgatgac ttcttgttgc agacgcgcag
    16861 taaaacggat aaaaatccgg atcgttttgt attgttttgt tggtaagaca tgaagattca
    16921 cgccttctgc caattgatac accatattta tatgctcctt ttcacagttg attgcccgct
    16981 tactctttta atgggtcaac ctgccttttt tacttattcc tctgcttgaa atttataagt
    17041 tcaggcaatt cgccgttttt tctaaatgat gttacacttt atagtatagc atagatgttt
    17101 tttatcaaaa gaaacagacg gctaaaagcg tatattgttt ttttattttt tatttttcga
    17161 tatactaaag acaaataaaa gaagggaggg tcattcatga tcaaagaatt caaagagttc
    17221 atcatgcgtg gagatgtctt ggatcttgct gtcggcgttg ttattggtag tgcgtttaca
    17281 agcatcgtaa accaagtggt gcaaggcttg atcacaccac taataggttg gtttgtcgca
    17341 atgatcacag gtacttctga tttagaagga gcactttcaa ttcttgactg gtcgccgaca
    17401 aaaggcgtca catttgcgtt tggtaacgtt attagtgcta tcattacatt tctgatcact
    17461 ggttttgtct tattcttagt tgtcaaagcg gcaaaccgtg cgaagaattt acgctccaaa
    17521 gaagagcaag tggaagtgga agaaactcct actgcagaag attatcttag tgacatacgc
    17581 gatcttcttg ccaaacaagt ggcagaagac aatacacatc cagtagagca aacaaatctt
    17641 tccgatactt ctaaataata aagaatctaa aaaaaagaaa gccgattttc agtgtcggct
    17701 ttcttttttt agattcttaa cttgctactt gttccttttt catgtcgata tgtggaatat
    17761 catcttccaa atacacatct gagattgcct tgaatccaaa cgactcataa aaagcttgta
    17821 ggtattcttg tgcgccgatc acgattggtt tttctggaaa atttttctgg atcatgttaa
    17881 tcgtttcttg aacaatcttt cttcctaaac catctttacg gttgtcctga tgaacaagga
    17941 cacgtccaaa atggatactc tccgcttctt catatactcg cgtgtaggca aggatcttcc
    18001 catcagtatc ttgaaaaaac gtatgccaag cttctccatc aatgtcatca acttcttgat
    18061 aaggacactg ttgttccaca acaaaaactg cgattcgttc tttgacgatc gcgtaaaact
    18121 ctgctgttga caattcttca aatttcttta cctgatattc cactaagcaa acgccccctg
    18181 cttttttatt cttagcatac cgattcgcac acaaaaaagc aaacgaacct tacgaatctc
    18241 aggctcgttt gctttttaaa ctgcttcagt taaaaattcg atctcaactg tccgagtaag
    18301 tacatctgaa tagctgtaag atactcgttc aaaagaattt tcttcaggat ccaaatcaac
    18361 aacgaatact gaaggatagg tttctgttaa aacgccgcgg cgttctgttt gacgctttct
    18421 tcctgtctga gcaaccaaca tgattgggct gccgatacga ccttctaaat ctttcttgat
    18481 tgaagctaaa gttgttggca tacagttcac ctctactatc aactatacca catattttta
    18541 aaattttcaa gtttaccata aaaaaaaaag aaatgcaata aaaataaata agaagctcat
    18601 taagattttt ctaaattatt cctcattata aaatttcaag tgttttttta ttttgagttt
    18661 tactctcccg taagcgctca ttacttgctt gtgatccatt gctaaacatt cagccatgtc
    18721 tacaaaatca acgccttgca tataataatg aaaaatttta gcttctattt ttgaaaactg
    18781 gatttcgcaa ttttcgattg cttcttttaa taaaagatgc tgaattgcta aaggttcttg
    18841 caatgtgatc tctgctaaaa agtctggtcc ttctgtctct attttttggt cgattgagac
    18901 ttcatctttt tgatcacgac gcttcagcgc gttctgcttc ctcaacagag aatagatttg
    18961 attgcttata acgcttttat aataacttcc aaagctaaca cctttgcttt tttcgtaagt
    19021 tctcaatgcc tgatataaag cgatccttgc ttcttgttcc caatcctcag aaacataatt
    19081 tcttaaataa taggtgtttt tcaaacgtag taaaagtgga aaatattttt gatacagggc
    19141 agcaaatgct tcttcgtcac cattacgtgc agcgcgcaat aactcctcag acataaaata
    19201 attcctccat aaattcgttt atggaggaat cttatcatca atgattcatc gaactgatta
    19261 gaacgatatg ttatttattt tttctcatta aatcgtccaa tttttgggac aattttttta
    19321 actgctcttc attccatgga gaattacgtc ggaaatcaat aaaatgcata tctttatttt
    19381 cttgggctat tgttttttcc gtttttttta tcgtcttata taattcataa gcagaagttc
    19441 gtaatgctcc ttgggaaaag atcatccact gttctgctaa atcgcttgtc gccactgtca
    19501 cttgtgtcaa acggtcattc agctgaccag cgattctctc gatataactg tcagccgttt
    19561 cgtcttcttt cgtaaaaaca acatccaact ggtatttctt ataattttgt tggatgcccg
    19621 gaactagttg ggcatcgaag acaacgatga cttccattcc ttcatatttc gcataatttg
    19681 ataaacgatg taaaagagct tctcttgcat ccgccatttt gtcctgcttt ttaagctgga
    19741 caagttccgg ccacgaacca atcatgttgt agccgtctac aatcaacagc tgttttttca
    19801 tggtctactc cccctgacgt tgggaaaaag cctgatacat aagcaaacca gcagcaacac
    19861 tggcatttaa gctctggacg tgcccggtca tcgggatcgt cagcaattca tccatttctt
    19921 ttttcaatcc tggactcatt cctttgcctt cattaccaat gactaaagca attgatcctt
    19981 tggcattcca tttttggaag tttgtgccgg tcatatctgt gccaaatacc caaaatcctg
    20041 tttctttgag ctgttgcaca gcttgtacca aattcgtcac gcgtgcaaca gggacatgtt
    20101 cgactgcccc agtggaagtc tttgttacga taggtgtgat tccaactgct cggtgttttg
    20161 gtatgatcac accatcgacg ccacttgcgt ctgctgtccg taaaatcgac ccaaaattgt
    20221 gtggatcttc gatgctatcc aaaatcaaaa agaaggggtc ttcttttttc tcttttgttc
    20281 gttcaatcag ttggtcaagg gataaatatt cataaggtgt aatcgcaaga acgactcctt
    20341 gatgcacgcc gtgatcgctc aaagtttcta atttttgttt aggaacccat ttgactggca
    20401 cagcttgttc acgtgcgatt tctttcagtt cttctacttt ttctcctcgt gaatcttctt
    20461 gaagaaagag tttattccct cgcccttgtt gtagcgcttc tactgcggca tggtgcccaa
    20521 agacgaaatt atcttctaat gcttcttcat tttgatcaga aactgactga tttcgtccag
    20581 tttgcttttt atttgaatat ctattttgtt ttttgtcttc aaatccacgt ttcgattgat
    20641 gtttgtttgt tctttcttta cccatttttt tcaccaactt tctgaataca ccagcggatc
    20701 aattcttcca tccgctcggt ttgttttgtc aaatgcagat agcccatgag cgcttcgaac
    20761 cctgttgcga cccgatacgt cgtaacatca gcattttttg cgctcgtatg gcttttagca
    20821 tttcttcctc tgcgataata aagttcttct tcttctgtca aaagatgttc ttccagcatt
    20881 tgctgaatca aaaaggcttg tgcattcgca gaaacataat tcgttgccgc acgatgcagc
    20941 ttattgggtt ttgtttctcc ttgatcaatc aggtggtcac gaacatagat ttcgtaaatc
    21001 gcatctccaa cataagccaa ggctaaaccg ttcaattgtg tgtaatctct catgcttctc
    21061 ttctccatcg ggttccttgc ggtgtatctt ctaataagat ccctttttct ttcaacaaat
    21121 cacgaatttc gtcgcttcgg acaaaatcac gattgcttct tgcttgattt cgttcttcga
    21181 tcaattgttc aatctcttca tctaataact cttctgctgt aaataaaata ccgaagatcg
    21241 aaagccattg cgagaataaa gcttctcctt gtgccaagac agcggcagaa actttcggct
    21301 ggtctagata agtgttcagc cacttagcaa gctcatagac cactgtgatc ccatttgctg
    21361 cattaaaatc atcgtccatt tcttcgatga atcgctgttc taaattttct aacaaagcga
    21421 ttttatccgc atcatctgcc aaattctctg aggcagtttc ttggcggaat ttcaaattgt
    21481 caaacgtatt cttcagtcgt tgtaaattgg tggctgcttc tttcatcgtc gtttcactgt
    21541 agcggatcgg acgacggtat tgtgtggtcg ccatgaagaa acgcaagact tgtggatcaa
    21601 cgtttttgat catttcatgt acagtgatga aattccctag agatttactc attttttcat
    21661 cgtcttcgcc aatcgttaca tagccattgt gcatccagta attagcgaat tttttccctg
    21721 ttttcgcttc actttgtgcg atttcatttt catgatgagg aaattctaaa tcttgcccgc
    21781 caccatggat atcgatcgtt tctcctaaat gttttgttgc cataacggaa cattcaatat
    21841 gccaaccggg acgtcctttg ccccatggtg aatcccaaga aatctcgcca ggttttgctt
    21901 gtttccataa agcgaaatct aatgggtctt ctttttgctg ctgttcttcc cctgtacgct
    21961 gacttgctcc gacttccagt tcatcgatgg attggtcact taatttccca taattttcaa
    22021 atttacgggt acggtaatac acatcacctg aagattcata agcatagcct ttttcaacca
    22081 acacttgaat aaatgctaaa atatctggca tatgatccat gactcttgga tgcagtgtag
    22141 caggttcgac attcaacgct ttcgtatctt cttcaaatgc tcggatgaaa cgatcagcaa
    22201 cttctggtgc tgtaatacct aattcgtttg ctgtacggat gattttatcg tctacatccg
    22261 tgaaattcga tacgaaatcg actttatagc ctcgatattc aaaatagcgt cgaattgtat
    22321 cgaaagcaat ggtgctacga gcatttccga tatggatata attatacaca gtcggtccgc
    22381 agacatacat accgacatgt cccttttgta tagggatgaa ttcttctttt tttctggtca
    22441 atgtattgta gatttttatc attctgatct cctcactttt tctcctttga ttcgaacgac
    22501 ttttgctggt actcctaccg ctgtagcgtc gtctggaaca tctttcaaca caacggcacc
    22561 tgcaccgatt ttggcgtttt ttccgatcgt taccggtcct aatatctgcg cattcgcaga
    22621 gagcatggct ccttgtttaa cagttgggtg tcttttaccc gtttcttttc ctgtgccgcc
    22681 taatgttacg ccatggaata aaatcacatc gtcctcgatt tctgcggttt cgccaatgac
    22741 gattcccatt ccatggtcga tgaacacgcc agttccaatc gttgctcctg gatggatctc
    22801 aacaccagtt aggaaacgcc agaattgagc attgatcttc gccaataaaa agagccggtg
    22861 ctgatataaa aaatgagaga aacgatgcca aaacaaggca tgaaaaccag ggtatgtcaa
    22921 aacgatctca gctgtcgaac gtgcagccgg atcgtttctc tttgctgcat caatcgctcg
    22981 ggtaaaccaa ctcatgactt tccactcctt tcgtaagaat tttatgtagg aaatcatctt
    23041 cttataaaga aaagaagcgc cttttaaata agtttcctta tcaaaagacg ctttccgcgt
    23101 ggttccactt ttcttcataa tcaatgatta tctctgacag ctaacgcctg ttatacgttc
    23161 ttggctactt tgtttcctat aaaacagttt ttcctgtttt ctgtgtttcg ccaagaccac
    23221 tcccagaggc atttcggcaa ccattcattg ataccttgca ccacccggta tctctcttgt
    23281 aatgatcagc tgcttacttt tttctgttca tcgtgtttag ttcagtactt gatttaaatg
    23341 tgctaatgat ttttcacgac caagcaattc gatcgtttca ggcaattctg gaccatgcat
    23401 ttgtcctgat acagctacac ggattggcat gaaaagattt tttcctttta cgccagtttc
    23461 tttttgaaca gctttgatgg cagctttgac agttggagca tctactactt ccatttgttc
    23521 tagctgtgct ttgaatgcgt ggagaacagt aggaactgtt tcaccagcaa gtacttcttt
    23581 tgctgcttca ttcaatacag gatgttcatt gaaaaatagc gtagacagat caacgatttc
    23641 tgcagcatag ctcatttgag gttgatacag gctaacgatc ttcttcaccc attcgattgt
    23701 cttttcatct gggttttctg ctacacgtcc atcagcgatt agataaggca gacacatgtc
    23761 agtaaatgca tctagatcca ttgctttgat gtaatggttg tttacccatt gcagtttttt
    23821 cgcatcgaaa gctgcgggtg atttacttag gcgttttgga tcgaacattt tgatcaattc
    23881 ttggtgttcg aagatttcgt cttcgcccac aggtgaccag cccaataatg caataaagtt
    23941 gaacattgca tctggtagat agcctaattc gcgatattgt tcgataaatt gcaagattga
    24001 ttcgtcacgt ttgcttagtt ttttacctgt ttcactgttg atgatcaatg tcatatgtcc
    24061 gaaggttggt ggtgtccagc caaatgcttc atagatcatc agttgttttg gtgtattggc
    24121 aatatggtca tctccacgta aaacgtgagt gattttcatc aaatgatcat cgaccgcaac
    24181 agcaaaatta taagttggca taccatcgcg tttttggatg acaaagtcgc caccgatatt
    24241 atcggattcg aacgaaatag cgcctttcac catatctgta aatgcgtatt ctgtattgcg
    24301 aggcacacgg aaacgtacaa cagattctag accttgtgct tctttttctg cttgttcttc
    24361 aggtgtcaag ttcgcacatg ttcctgcgta atgaggcatt tctcctcttg cgcgttgtgc
    24421 ttcccgttct gcttctaatt cttcttctgt gcaatagcat ttgtatgctc gattgctagc
    24481 aagcagctga tcaatcagcg gttgatagat ttctttacgt tcagattgac ggtaagggcc
    24541 gtattctcca ggattttcag gagattcatc ccaattcatt cccaaccaag caaggttttc
    24601 caactggctt ttttcgccat cttcgatatt acgtttttgg tcagtatcct caatacgaat
    24661 aataaagtct ccatcattgt ggcgggcaaa caaataattg aataatgcag ttcttgcatt
    24721 tccaatatgc aggtgcccag ttggacttgg tgcatagcgt acgcgtactt tcgtcatttt
    24781 cttcctcttc tttcaaacta gactttgact aacagcaaaa attccgtcag ttacggcttc
    24841 tcaaatatca tttatttaaa gccactcagc acaaatttta ccttttctaa ggtaaatagt
    24901 aaagccaact ggttgaattt ccttaccagt tggctgaatt tcttttttat tttgattgtt
    24961 tagtcttttt ctctgtctct tttttattgt cgattcctcg tcctgcatgt gcaggtttag
    25021 caaagatcat gcgtccagca gctgtttgaa gggcacttgt tacaacgact tcgatacgtt
    25081 cattcatgta atgctgtcca tcttctacga caaccatcgt gccgtcatca aggtaggcta
    25141 ctccttgttg gcgttctgtc ccggctttta ctactagaac attcatcgtt tcaccaggga
    25201 tgacgactgg ttttacggca tttgccaacg cattgatatt aagaacaggt acattttgga
    25261 attcagagac tttattcaag ttatagtcat tggttacaat gacaccatct aaaagcttag
    25321 ccaatttgat caatttgctg tctacttcac tgatatcttc aaagtctcca tcgtacattt
    25381 cgacagatat accctcttct ttttgcaagg catttaggat atctaatccg cgacgaccac
    25441 gcacacgttt caaactatcc cctgagtccg cgatgtattg tagttcgtaa agaacaaaat
    25501 tagggatcat caaggttcct tctaagaatc cagtctttgt aatatcataa atccgaccgt
    25561 caatgatcac gcttgtatcc aagattttat atttatggaa attttctcct gattttcgtt
    25621 ctaacagttg actctcaact tgactagctg tttcttgctc gatttttttg cttcgtgaac
    25681 caaaaacttt cttccattct tcgattcgtg tcgttcccat tctcaatccc agatagccta
    25741 agatgatcat cagtaaaatc ggcaatacac tattgacgaa tggaatttcc atattgtaaa
    25801 gaggggtcga gatcacaaca cctaaagtca atccgatgat cgcaccgatc gcaccgaaga
    25861 gaagataagt caagctgacc tcacttagtt tttgttctac ttgtttgata atagctgaga
    25921 tatgtttggc caacagcaaa gataataaaa agaaaataag tgcgcctaac aggctgttgg
    25981 taaatgtatt attcagccat ccgtttgact gttgaccgat tgcctgccaa gctgagggta
    26041 aaaatgaaat acccaagctt gcgccgacaa tgatcatcag caaagtaatg acacgttttt
    26101 gcatcgtttt tcctccgttt cgacaatcat ttattagtta gcggaacaca cgcttcaacg
    26161 tttcagccaa agttgctact ccaactatct cgattccttt tggcgcttcc cagttaccta
    26221 agttgttttt aggtaggtat acttttgtga agccgagttt ttggacttct ttgactcgtt
    26281 gttcaatatg actgacacgt ctgatttctc cagtcagtcc aatttcaccg atgaaacatt
    26341 ccgttggctg tgttcctttt tctttatagc ttgaagcaat actgacagcg atagctaaat
    26401 caatcgctgg ttcatttaat tttaccccac ctgcagcttt taagtaagca tcttgattct
    26461 gaagaagcaa cccagctctt ttttccagca ctgccatgat cagagatacc cgattgaaat
    26521 caagacctgt tgttgttcgt ttggcatttc cgaacatagt aggtgtgact aatgcttgga
    26581 tctctaccaa aattggacgt gtcccttcca ttgccacaac gatagcagag ccagttgcac
    26641 cgtctaggcg ttcttctaag aaaatctgtg aaggattagc gacttcttcc aatccatgct
    26701 catgcatttc aaaaatccca atctcattcg ttgagccaaa tcggtttttt actgctcgca
    26761 aaatccgaaa actatgatgt tgttcacctt caaaatataa caccgtatcc accatatgtt
    26821 ctaacattct tgggccggcg atcgagcctt ctttggtaac atgaccgacg ataaaaatgg
    26881 ctatcccatt tgttttagcg gttttgagta gttctgcagt ggtttctctt acttggctga
    26941 cacttcctgc cacacttgtg atgtctggct gcgtcatcgt ttggatggaa tcaatgataa
    27001 cataatcagg ggagatatgt tcgatggcac gactgatttc gttcatatct gtttcagcgt
    27061 atagataaaa ttctgtgttg atacttccga ggcgttccgc gcgtaatttt atctgctctg
    27121 cgctttcttc gccggataca tataagactt ttccgcctat ggctgctaat tgctgagaaa
    27181 cttgtaacag caaagtggat ttcccgatac ctggatcgcc accaatcaag accatagacc
    27241 ctggcaccac acctccgcct aacacacggt tcagttcttc taattttgtt ttgatccgag
    27301 gttctttttt agggacgacg tctgcgattt ttgttggttt tgctttttct cctgtcaaac
    27361 ttgtccgagt tctgcggtcc gttgtatctt gttcgatttc ttcgaccatc gtattccatt
    27421 ttccgcaatt tgggcagcgt cccaagaact taggcgacac atacccgcaa ttttggcaaa
    27481 caaattgtac ttttgatttt tttgccattg taccgcctcc ttttatccta atcatgagac
    27541 attaaatcaa gcttaagtat ctttaacgtt ttatttactg gaagaaccaa atccgccttg
    27601 acgttgagca gtcgtttgat cttgatctgc ttttaaaaac ggcaaaaaga tcccttggcc
    27661 gatacgctcg ccttttttga tcactacatc cttgaaacca aagttggtga attggaacat
    27721 gatatggcct tcatttgcct cattattgta ataatcactg tcaatcacac ctactccgtt
    27781 tgtcaacact aaaaaccgct tcaacggatt gcttgaacgg ttagcaagct gcaaaaattc
    27841 atcttctccc atgtaagaag ctttgattcc agtaggcacg agggttggtt tcaattgttt
    27901 ttcattttct gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca
    27961 gcctgctttc cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc
    28021 agcatgatgt gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac
    28081 ttcaaatcct ctttttctca ccggttttcc tccctaaata aactactcct attctaacat
    28141 atccgaggct gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt
    28201 aaaccattaa ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta
    28261 catgacttta ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt
    28321 gaggtgtcac atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac
    28381 aagtacattg atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt
    28441 tgtcctttct gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt
    28501 aggcgttggt atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca
    28561 agctgcggcg gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt
    28621 atataatcaa cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag
    28681 tcgtaaaaat gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt
    28741 gaacgaaaac gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa
    28801 tgatcagctg tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc
    28861 tgatatcgac gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg
    28921 ctatatcgat aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt
    28981 tggaacaggc ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag
    29041 cgcaatgatt ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa
    29101 agaagtaggt actttattta aggaggactt gaaatgactg acttgatgca attaggacaa
    29161 caggcaaaag atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta
    29221 cttgttcaaa tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat
    29281 aaagacttag aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag
    29341 ctgacacctg agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac
    29401 gatcctattg gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa
    29461 aagcgcgtgc cactaggcgt gatcggcatc atttacgaat ctcgtccaaa tgtcacgaca
    29521 gatgcagcta gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa
    29581 gcattcttct cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc
    29641 gaatctcctt atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg
    29701 atgcgattga cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa
    29761 cgagtcaaag aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta
    29821 tatatcgata aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct
    29881 tcccgtccat ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct
    29941 tttttcttgc cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat
    30001 gctcgtgcgt tagaatatct agagacggct gctttagcag aagacacaga ttgggatact
    30061 gaatatctag attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca
    30121 catatcaatc ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct
    30181 agtcaacgtt tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt
    30241 tttacagacg gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg
    30301 catgcccgtg gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc
    30361 gatggacaaa tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt
    30421 tctgtaaagg ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt
    30481 tttatttacc ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt
    30541 ttctttcaat tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt
    30601 gacaaaatcg ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta
    30661 tgcttattag cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt
    30721 acgctactga ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac
    30781 ttgaatcgga ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg
    30841 caaaaaactg ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc
    30901 atataaacgg cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc
    30961 gaaaatccgt caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc
    31021 atcgtttttt ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga
    31081 tacataccag ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt
    31141 ggcaattctt tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat
    31201 tcaacgagtg tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt
    31261 ctttttctta aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag
    31321 aaaaaaaggg aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc
    31381 ttctgccaac tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg
    31441 aaattgttcc ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt
    31501 tcaatcagct gaccctcggt attagctcaa aaaacggtaa aatatgagaa gctatttttc
    31561 cgttttgttt ctctaatact taggataaaa cgctgatttt acaacctctg ttaaacggtg
    31621 ttcaatcagc tgtccttcgg tattagctca aaaaacggca aaatatgagg aactattttt
    31681 ccgtttgttt ctctaatact caggacaaaa cgctgatttt acaacctcct gataaacggt
    31741 gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agaagctatt
    31801 tttgtttggc tgttcttatg acttgatgca ggacagcttt ttcacaacct ctgatttctt
    31861 attcttcttc atttgtagca aaataattac ggtgataaat gatacaacat acactgataa
    31921 gaacaatggc acctgcaaaa taaaacgcat agctttcacc aatatgttca ccaatcacac
    31981 ctgcaataaa tggtgctaaa gctccaccga aaaagcggac aaaactatag ctggacgaag
    32041 caacgtttcg ttgcagacct ggtatttcca tagcaatcgt cgtcaacagt gtattgataa
    32101 ttccttggaa aaatcctgct aacacaatgc tgatcggtac aaggactggc atagaagttc
    32161 cagctcctaa taacagcaaa caaataatga ataagacaaa tgctgctaaa attgtccgat
    32221 aagtcgtaaa cttccgctca agagccggtg caacgaaaat cgaagcaata gccagaagca
    32281 caccccagcc aaaaaataca aaaccgactt ctaattcaga atagccaatc aataaaaatg
    32341 gcgcatacgc aagtaaagta aagaatccga aattatataa caatgcgatt agtccaactg
    32401 aacgaagttt atgattgctt aacgctttga caccttccca aaggcctact tttctctttg
    32461 gtttctcagt ttcaggtaaa agtaccgcta gggctataaa accgcaaaac atcaaaaatg
    32521 ctaccccaaa aaatggataa cgccatgaac cactgcccaa gaccccaccg actagagggc
    32581 caacagccat tccgcagcca agtgctgctt catacatcat gattgctttt tctgtgttac
    32641 caactaaaat actgacgatc gttgctaaag cagtagagac aaataaagca ttcccgacac
    32701 cccagccggc acgtaaccca atcagcattc cgatattccc agataatccg ccaagaccag
    32761 cgaatacaac gatgataaac aatcctgtca tcaatgtttt tttcaaaccg atccgactag
    32821 ataagaaacc tgtaaatagc atcaccacac cagtgactaa catgtaacta gtaaataaca
    32881 gggtcgtttc agctggcgta gcgtttaact gtgcagcaat cgtttttaag attgggtcta
    32941 ctagacccac tcccataaaa gcgatcatac aggtagctgc tacaactagc gctgaacttt
    33001 tcccctttgt ttcttcattt gtttgttctt gtatatctat ttgattctcc aatatttcca
    33061 tccctttctc tctattagca tcatacatga tttattttac atgtcaatat gcacatgtaa
    33121 aacgtggaaa ctttactgtg atataataaa gaaaataaga cgagaggtag gatttttatg
    33181 aatactttag cctatatatt attatgcgtg cttttatcca aaccacgttc tgggtatgaa
    33241 ttgaagcagc tgatcacaat tttttgggaa gcccatcaca gtcagatcta tacaacgctt
    33301 gccaagttag accagcaggg ttatgtgacc gttttggaca aagacgagca ctctcaaaaa
    33361 aagatctacc acttgactga tgaaggacgt gctcttgtag aggaatggat caaagaggaa
    33421 actcccgctc ctacgcaaaa agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc
    33481 gataaaacaa cagctactgg actgctattc actagagaac aacagctgaa caaaatcatg
    33541 caaaaaaatc aaaaaaaatt gaatgacctc tcgctagaca agaaacaaga atttggacgt
    33601 tatgttgtga tccagcgcag aattatgctt tgtcagcagg aactccaatg gtgtcagcaa
    33661 gtaagagaac aaatgcagca gttttttgag taagggataa acagaacctt tctagaaata
    33721 tctattgaag agcaaattat cttcaataaa agagcaatac agttggaaaa gaaaaagcga
    33781 tccgaacgac aggccaaaac ctatcgttcg gatcactatt tttctagaac tgcattcaag
    33841 agactatgac aaaaagcatg ccaaggcctt ttttcaaata acagtgttcc atcattcatt
    33901 actttgaatt gcttttagca cacttcttga aagcgggcca acgatgatca actgcaacgg
    33961 taaagcggca atcacattca ttttccaagc attcatataa gcagagaata attgatcagg
    34021 tattccttgt tccatgatca caccgaataa agacatacat gtcaccattc ctaaaaccat
    34081 caagcatgaa atagttaaga tcatttggac cttgctttct ggatttactg gtagtttaaa
    34141 ggcaattttt ttcgccagca caccgatgat gaagacatcc aaaatgaaag ccaccacgaa
    34201 tccaggcact agaccaatca acaaacttga taaatgaaga tcttgatgca gccataaatt
    34261 atacgcgctc atccccaaga ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc
    34321 ttttttattt gtaggcaatc tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc
    34381 acatttaaaa atttctcgta agtacttttt ttattttctg cccttttatt tcataaactt
    34441 catcagccgt acgctcgaca aagtaagaat catgagaagt aaacaaaatc gttcccggat
    34501 atatttgcat tagcttctct aaagcttcga tcgttgccat atcaataaaa ttagtcggtt
    34561 catctaacag caacacatta cttggcttag taaaaagcaa agcaatcgtc agacgggtcg
    34621 cttctccccc acttaatgta cataacggtt tcgtcaaagt ttcctgagca aaccctaagt
    34681 gattcagcaa actacggaca agcgattctg aaaactctgt ttgtctcatg acaaaacgaa
    34741 tgatggattc ttcagatgtc atttgataac ccttttgctg atatacttga aagcttactt
    34801 tcggagagag aaggattcct tctccttgtt tgcggatatg ttctaataag gttgtcttac
    34861 ctgaaccatt ttcaccgaca atcgcgattt ttttacctaa agaaaactga aaatcaccat
    34921 ttaccagtaa tgttctccca cttctttcca attggacatt ttgtcccatg atgggatagc
    34981 ggctgtggag ttcaagagat tttggtactg gaaaacggat ttgtttcatc tgctgcggct
    35041 tggttgtttc tcctattttt tggagtcttc tctctaatgt tttcgcattc ttttggatgg
    35101 ctttttgtac actgtctttt tgtttagagg aagacaaccg atccagtctg atttgttgct
    35161 ttttcttttt actggacact ttttccaact tttccgcttg ttttttcttt tcttggatcg
    35221 atttttccaa tcgttttttc tctttcatga tcgactctgc ttctcgtagc tgagtctttt
    35281 tctccaattc cttttgagtg agataggcac tataattccc cgaaaactct cggatttctc
    35341 cgtcttttac ttcccagatt ttcgatgcta gctcatctag aaaatagcga tcatgactaa
    35401 caaaaaccag cgtaccataa taataacgaa gctcttcaat cagtcgatca atactttttc
    35461 tatctagatg ggttgttggc tcgtctagaa gcatcccttg ttcataagaa gaaagaagac
    35521 gtatcaactc gatctttcgt tcttcccctc cgctccattt ccgctctgaa gtttcttcca
    35581 gtcttaactg gaaatgactg gctaattcca aatttaggtc ctttgcttca gcgagatagg
    35641 ttaattgagg caggtagttg aaggtgatct ctgtttggat tttcccatga tcgggaaaaa
    35701 gttcaccggc tattagtttg agcaaagtcg atttaccgac accattttct cctatgatcc
    35761 ctatacgatc ttgctgatag acacgaagag aatcaataga tagttctagc tggttgccaa
    35821 agctgacttg tagatttgtt atatttactg ctaaattttc catatgtttt acactcctat
    35881 ttcatgtaaa acaacaatta tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa
    35941 actgcatcac atcttttcct actctgaacg aaataactat gactaaatca ccaaatctgt
    36001 catagctttc acctattcta ctgtcgttcg aaaaaatgga catactccat ccatgaaatt
    36061 gttgtttata catgtctttt gaatttattt agttgttatt caaaagttcg aaacgtaatt
    36121 tcatcgatgc agtcattttt ccgacctcct tttttattag gttaccacac acgattcaaa
    36181 aaaagcaata gctactgaat agtaactgaa aaccttttat tcgaacatag tgatcttttc
    36241 tggtgctaaa cgaacagact cgtaaccttc ttctaccgct tttcctattg ataaaataat
    36301 aactggaaca taacggtctt tatccaaacc aaatgcctct gccaactgat ctgcttcgaa
    36361 tccaccaatt ggatttgttt catagccatg atcacgcgca actaacatga attgcatagc
    36421 cgctaagcta gaatcgactt tgactacatc gttcatttct tctcttgaaa aactcttgta
    36481 ataaggaatg atcgcagcta attgttgatc tctgacttct tttggcatct tccctgattc
    36541 gtaagcttgg ttgtagattt cttcgccata ttcgtaacat tgcatatcgc caaaaatcat
    36601 gaccattgca gaagaagtat cattttgtct cgtattgaaa cggatcaaag gacgcaagat
    36661 ttcttttgct tcctcgcttt cagcgaccac aaagcgccat ggtttcatat tgacagaaga
    36721 aggtgcagtc gtcgcttctt tgatcatttc cagcatttct tcgtgtggga ttttgtatgt
    36781 ttcatcatat acgcgaacgg atcttctacc agtcataatt gttgaaaaat catttttttg
    36841 ttccattatt attaacctct ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt
    36901 tatctaaaag tgttagaaat tgtttcattt ctacatcgct gaaagccggg gatagcacgg
    36961 aacctgtatc tttatggtcc atttcacaat gcttgatttt cttctgggct ttttctgtta
    37021 gcgctacata cacttcccgg ttgttctgag gatttctctg acgcgaaaca tagccatttg
    37081 cttccaatac cttcagatga cgagtaactg ctccttgatc aatctgcaac ttttcttgca
    37141 aactgctttg tagcaatgga ttttcttctt tcagtctcat catgatctcg tatctagtaa
    37201 gacttatacc gatattttct tcaaagatct ggacgatttt ttgatcggct aatttgattt
    37261 gatataaaag gtgactaatc tcttctaaag acataatttc ctcctttcta ataattgact
    37321 cgtcaacgat tgacttgtca ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg
    37381 tgtaataaaa aaaacgctct caatagaaaa gtatagagaa aagaaatttt ttgtagaatg
    37441 aacggaaaaa atgataaaga aagcacaacg ctaaaaccaa gattattgat tcttatcaaa
    37501 ctatagaaga tagctcttct gcagtagata attttacacc gccaaaaatt tccgaaatcg
    37561 ccttttgcaa gaatcccgtc gaatattaga aattggatca gtatgcttaa acagtaataa
    37621 aaaagttatg acaagatgtt gtcacaacct tttttgagta aacggtgttc aaaaacttgc
    37681 atctgcggta ataagttcaa ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt
    37741 cttactactt gatgcagggc agctttttca ctacctcttt ttaataacca taaaatccta
    37801 ttccttcata tctccagccc atcggtgtta gccaatctct ttccttagca ctcaaggtat
    37861 agtgatgggt accagttttt tcatttggat taaatagtcg ataaattggc ttggaaccac
    37921 cagaataaaa acttagacct tcataacgcc aaccgatttt tgttaaagag ttgatctcag
    37981 attgtgccat tgtgtaatga tggtctccac tgtaaggatt gtataaacgg tagacaggtt
    38041 gtccgctgtt tggtgcttgc caagcaatcc cttcatattc ccagcctaca gttggcagat
    38101 aatttttttc tccggcattc aatgtatata aatgttctcc tgtatgacgg ttatacagac
    38161 gatacatcgg agaagttgaa gttggtgctg tatcatactg tgtcagatta taggtttcga
    38221 ttacattgtt caatgtagaa ccataattag gcgcagtggc ataacgacct gttagccaag
    38281 ccgtagcatc tttgtaagag ttcgtattgc ttttccatgc accggaatag tagtaaacgc
    38341 ctggctgaaa agaagtcgtc ttcaataccg ttacgttatc ttgcaatgat tctttgtacg
    38401 aaggatattt tctaaaagcg gcattcaccg taatccattg cccattcaca tattccgaag
    38461 taggcatcgt aacagattgg ccattatagc ttcctttaat cccaaataga ttgtaattag
    38521 gggcagaagc caaagtactg ttcccccagc cactttcaac gatggcttga gcaatcatga
    38581 ctgatgcata taagtcattg gcacttgcca aactttgtgc agttgaggca atactatcaa
    38641 tgaacgcttg ttgagaatta gcagatgagc gagcataaaa agcatagcca gtatagtttt
    38701 cgaattcaga caaatctgct tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt
    38761 tcgtgatttc ttctgcattc tctggattgt tctgagcttc tgctgatgta ctgtcttcgg
    38821 tttgtgtttg ttctgttgtt tcagttgttg gttcttcggt tgaaattgta ttttctgaga
    38881 cagtagctga ctgcaaagta ctttctgtat cgttttcaat tcctgtttct gaagaactcg
    38941 atgtctgagt tgcgacagtt tctgtcgatt cttcagctag cactgttgtg ttggcaactg
    39001 ctagatttcc taaaagaata acgctaaata ataaattctt tgctttcatc ttttttctcc
    39061 tttgaattat gaaacttttc ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat
    39121 gtccatattt aaataacatt tgtttctttt taataaattt gctttttctg cataaaaaga
    39181 cgtaaatgaa gaatattctt ctccattcac gccttaaatt gatggtcgtt tgaataacta
    39241 tttaacaagt aattctctct ggatattatc cgttatggat tatacttcct gtgtcgtcgg
    39301 acggataatc atgttgctga cagacatccg gtctggcgtt tctatcgcaa atgctacagc
    39361 agaagctata tcttcagatg ttaatcccca ttctttttgc gcttcatgaa gttcaagagc
    39421 agcctttttg tcgctgatgg tttgatataa ttcagtttga acagctcctg gagagatgat
    39481 cgtagatttg atgttatttt gccgttgctc ttgacgtaat ccttccatga ttgcacggac
    39541 agcaaatttt gttccgcaat aaacggcgga atcaggataa acaacatgtc ccgccacaga
    39601 atcagttgaa atgatatgcc cagatttttg tttttccatg attggaagta cggcggaaat
    39661 tccatttaac acacccatga tgttgatatc aagcatattt tgccattcat cacggtgacc
    39721 ttcaactaat ggagcggttg gcatgattcc tgcattattg tacaatacat cgattcgacc
    39781 gaacttttcc atcgctaaat cgataactgc ttggacttgt gcaaaatctc ttacatctgc
    39841 tgtttgaata tatagctcag cttctggtaa agattctttt attgctttta ggcgatcttc
    39901 tcggcgtgca gctataacta gtttagcccc tttttctgct aatagcttcg ttgttgcttc
    39961 accgattccg cttgaagcgc ccatgatgac aatcactttt tctgataaat cattcattct
    40021 attctcctcc tgttttgaaa aatctcttgc ttatactcac tatctcttat ttcatcttac
    40081 tgttcaaata atccgttcga caggtttgac gattttggca gggattcctg caacgatggt
    40141 attgtctggg acatctttcg taacagttgc attcgctgca acaatggcat tctcgccaat
    40201 cgttacgcct ggcagaatag ttgctcctgc tccgatccaa gcatttttct tgatgtggat
    40261 tggctttact gacaagcctc ttcgttcttt tggatcggtt agatggttca ccgtgatgag
    40321 gttgacacga ggaccaatca atactgaatc ttctaaacag atgccaccta agtcaacgaa
    40381 catcacttga cgattgataa agacattttt ccctatacta atatgtttgc cgaaatctgt
    40441 ataaaaaggc agcagaacag tcaccgtatc atctactttg tcactaatga tattttctag
    40501 ccgtttgcgg atatctgctg gttcatggta cccagtattc agcgctgcta aaggctcttc
    40561 gttttccgct tggatctgat ggatcacttc aaagagcgga tccgttactc gaatctcttt
    40621 attgacgatt tgtttttcga tgaggcttgt cattttgctc cctcctttta tccttacttt
    40681 ataacggacg gcttatgatg tctaatactt ataaaacata cttaactatt ccttttaact
    40741 atacttagtg gtatgctttt ttaaaaacag gagggaaaaa atggatattc gtatactgac
    40801 gtatttttta gcagtagcta gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat
    40861 cacgcaacct actctctcaa aacaactgaa agatttagaa gaagaacttg gtgtgacact
    40921 tttcactcga ggctcccgag agatacagtt gacggattct ggtcgatatc tttattcaaa
    40981 aggaaaagaa atcttgtcgt tggtagaaaa aacggcgaac aatttaacaa atgacgcaat
    41041 catctctgga gaaatctaca ttggcggagg cgaaactaaa gcaatctctt tcatttctga
    41101 tagccttcat tcgttgatca aggcgcatcc tgatatccag tttcatttat atagcgggaa
    41161 tgcagatgat atcatagaca aactggatag cggattactt gattttggac tcgtaatcga
    41221 accgacaaac aaacaaaaat accagtcatt tcgactgcca gcccaagatc gttggggact
    41281 tttgatacat cggaatcatc ctttagcaaa gcaaacagtc atccatccgc aggaactgaa
    41341 aactgttcct ttgatcattt cccggcaaac gtcagtggac agtcaactag ctgaatggct
    41401 aggtttcagc atagatcagt tatcgatcgt cggaacatat aacttattgt acaatgcttc
    41461 tttgatggtc gataacggga cttttggtgc attagctcta gatgggatca tcaatactta
    41521 tgggacggaa aaagtattca tcccactcga tccgccatta caagcttcac tgaatctcat
    41581 ttggaaaaaa gaccagcctc tttctcctgc tgctcgtaaa tttttagatg tcctaacgga
    41641 gaaatacagt taagtagagt ttttttcctt cgctttcagc tttttaacaa cgaataagtt
    41701 aagcaaaaga tccaatgatt aaataacata agtttcttaa tttgttcctt ccttttattt
    41761 ctgataattc cagtaaatta ctataattat aaaaaaagaa ttgacaaaac ataactgtct
    41821 atataaaatt gattacgtta acaataattc gtttcatgtg actagatcat actaggcatg
    41881 aaaaatctct gaggaacatg gtttccctag gaggtttttc gtgtctattt ttgtttggcc
    41941 gcaatcaact ggtctagcaa acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa
    42001 atcaaaaaga tctttaatca aaatgcagta ttggtagatg acggtggaca ggaaaaagta
    42061 gctattggaa aagggattgg atttgacaga aaaagaaatg atttgatttt tgatcgtgat
    42121 gtcgaacgga tatttgtcat ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat
    42181 cagattgatg aacgcttttt atttgcagca gaaacgatca ttgatcatgc ggaaactgtt
    42241 ttgatggaaa agttgaatga acatgtattg atcgctttga ccgaccacat tgctttttct
    42301 gcggagaaca ttaataacgg tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg
    42361 ctttacagtg atgaattcag tattgctcaa tgggcagtag agtatctgac aaaagagctt
    42421 gggattccat atacttatga cgaagcagga tatatcgcaa tccatattca cagcggacga
    42481 agcggtcgga acaataacca tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc
    42541 catttagtgg aatcagaatt ggaaacagat atccattcag aaccattttc actgaattat
    42601 tcaagactgg tgaatcattt acgactgctt ctacaacgaa cccatgcgca acaatatgct
    42661 gttttagaca cggaaatcgt agaaatggtc aaacgaaaat acccagaaag ctataagatt
    42721 tctaaaaaaa tccgtgtgtt gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa
    42781 ctgggttact tggccatcca tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt
    42841 aacaatcatg aggaggaaaa aaattgaaag catatctaca acgaatggga cgttcccttc
    42901 aacttccagt tgcggtctta cctgctgctg ctttactagt agggatcgga aactggtggg
    42961 catcttatag taacgacatt gtcgctcatt ttttacaagc tggcggtaac gcagttttag
    43021 gtcaattacc tttgctgttt gccgttgggt tagcactagg gatgtcagtg gacaaatcag
    43081 gtgctgctgc cttggcaggt ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg
    43141 attcagtagc tactttattg aatatcaaac cagaatcagt tgatccatct tttgctcaga
    43201 tcagtaacgt atttattggt attattgccg gattgattgc ggcagctctt tataatcgtt
    43261 tccacgaagc aaaattaccg atggctttat ctttctttag cggcaagcgt ctagtgccaa
    43321 tcttggctgc ctttgtcatg ttgctgatca gtgcagtgct actgctcgta tggcctccgg
    43381 tttactctgc tttagtttct tttgctaaat tcattttgag tttaggctgg ggtggtgcag
    43441 gtctttatgg cttcttcaac cgtttactga tccctacagg attgcatcaa gcaatgaact
    43501 ccgtgttctg gtttgacgta gcaggaatca atgatattgg taaatttttg gcttctgaag
    43561 gaacaaaagg cgtaacagga atgtatcaag ctggattttt cccaatcatg atgttcgggc
    43621 ttccagcagg agcatatgct atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag
    43681 cttccttgat gttagcagca gcttttgctt cattctttac tggtgtaaca gaaccacttg
    43741 aattctcatt tatgttcgtt gcttggccat tatatgtctt gcatgcaatt ttcactggga
    43801 tttctttagc agtgagtgca ttcttccatt ggacagcagg atttgccttt agtgccggat
    43861 ttgtcgatta cttcctatct ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg
    43921 tccaaggatt agtaacagca gtgatttact actttggctt taactttgct atcaaaaaat
    43981 tccatctgat gactcctggc cgcgaggaag cagatctttc agatgacgat actgcaacga
    44041 ctaattcaga caataaatat gcggcacaag caagcaaaat ctacgctgca ttaggcggag
    44101 ccgacaatgt aacttcgatc gataactgta ctacacgcct tcgtttgcaa gtcaaagata
    44161 caggcctgat cgatcaaaat aaaatcaaag ccactggcgt acctggtatg aagatcatcg
    44221 acggaaaaaa tgcgcaagtc atcgtaggta cagaagtaca attcgttgca gatgagatgg
    44281 caaaactaca tggtggtgct gcaacacgac ctgcacaaac aaacaccgtg gttaaaacag
    44341 aaacatttgc cggtggaacg atcgaacaag atatttacgc tatcgcaaat gggaaactga
    44401 ttccaatcac tgaagtttca gatgatgtat tcgcggaaaa aatgatgggt gacggctatg
    44461 ctgtattacc agaaaatgga gaaatcttct ctccaatcgc tggtacgatc acaaacattt
    44521 tcccaacgaa acatgctgtc ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata
    44581 tgggcatcaa cactgttgac ttaaaaggcg aaccattcac tttatatgta aaagaaggtc
    44641 aaaaagtcgc aagaggtcaa ttgattgctt tagttgatct tgccgctatt caatctgcag
    44701 gcaaaaacac ggatatggtc gttgtattca caaatggcga caaagtccaa agcttagaaa
    44761 tcgaacccgc acgtgatgta aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct
    44821 gagccatcgt cttccccaga cttttttatc gataaacaaa caggagctga gacaaaaatc
    44881 ttgtctcagc tcctttttcc gaataaaaac ggcgttctcc tgccaactcc gcggtaataa
    44941 gtccagccaa acgtaacata tgaagagcta ttttttattt gactcttctt attacttgat
    45001 gcagaacagc ttttttacaa cctctgataa acggtgttca aaaaccagtt tatcggtatg
    45061 aagtcaaatt tatgcaaaaa tgtggaaagc cattttcaca aaatttttct tcatactcaa
    45121 aactaatcgg ctttttcaca acctctttat acattattcc tgatccaata tttcttttaa
    45181 tgctgcttca agagaagtta atggttttcc caatactttt tctaaatcat cagaggaaat
    45241 agctaactga tcctttttaa tatcatgttg gatcgctaaa aacatgtcag ctgcttcttg
    45301 agggaatccg gcttctttta gattttcgac aaacgctgca tcacttgctt caataatttc
    45361 taacttttta cctgtcgcac gctctaatgc cttggctaat tcttcatagt cagttagatt
    45421 gccggataat tctaagattt ctggagagtc actttctact agtacttttg ctgcagcttc
    45481 tgcatattca cgtttcaatg cccaacctgt ttttccattt cctgcagcat aaacgaattg
    45541 accagttttt aaagcctgcc caatgatagg taattcattc tctacatacc aattattccg
    45601 taaaaatgta tgggaaatac ctgaatcctt aatcattttt tcagtgaatt ggtgatctgg
    45661 cgctaataca ctgatcgagt gatcggcatc tgcaaaactt gtataagcga tataagatac
    45721 cccagctgct tgtgctgcct tcactacatt cttatgttcg gcttgacgat ttcctggaac
    45781 gccagagaca aaaagcaatc gatctattcc tttcaacgct tctttcattg agtctaaatc
    45841 atcataatca ccaatacgta tattaaatcc agcttctttc agtgcttctc ctttttcttc
    45901 actacgtact agtacataga tttcattttg tggaaccatc ttttttaaga attccagcgc
    45961 ataaccacca aaacctccag ttgctcctgt tactaaataa tgcatatttg ccactcccta
    46021 ttctttttat ttgttaagat ttacagctgt acatttataa attacacctt tatcataaag
    46081 agtgtggtaa gataagtcaa gcaaaaaaaa tgaaaggatg acaactgatg aagtattctc
    46141 tgcaatttag tgatgcaatc catgtacttg cctatattga aatgtttcaa gatacccgat
    46201 cactttctag tgagatgatt gccagtagta tcgaaacaaa tgcagcaaat gtacgtaaaa
    46261 tcatgagtca gctcaaaaaa tccggtttga tctttacaaa aaccggaaaa ccgcagcctt
    46321 cccttgccaa aagtccagat cagatttctt tactagatgt ctatcgcagc atcgaaggta
    46381 atacacagct tatccaagtc gatccaaaaa caaatccaaa ttgcgtcgtt ggtgcgaata
    46441 tccaagaagc tttagaagaa agctacgctc ggctgcagaa aaaggcagaa gaagaaatgg
    46501 ctaagatcac acttgatagt ctgatacata aaatagccgt tttggaaaaa gaaaaaagac
    46561 cagaaaacac aggcctcgta gagagatttt tataattctc tctactgtgc ctgcattttt
    46621 ctgatcggaa tcgtctacat aaattctttt attctccggg ggacaaaagc cttgtcatgc
    46681 ccctttttcc tctctaatgc tcaggtcaaa gcgctgaagt catgacgtct tgataaacgg
    46741 tgttcaagta gctgaccctc ggcattagtt ctgaaaaatg caaaatatgg aaagctattt
    46801 cccatttttc ctctctaatg ctcaggtcaa agcgctactt tcacgacctc tatattatca
    46861 tggtttattg actaccggta tccagatttc tcccatatat ttcccgttgg taactcccat
    46921 ttcgactaca gcatttggac ccccaacata ggcgtaatct tctacttctc ttaaaacatg
    46981 cccaaaggcc gtattcgtca aatcatttct taattcttca ggcgattctg ctaaagcgat
    47041 tacaacaaga tacgttcctt ttgggaatgg gatgattcgg gtagtgtttg gaacatcctg
    47101 actcgtttga acaccgacat agtacatcat tttcccgtta tagggttcgt tgactgtaaa
    47161 gaaataatga ttttcagcag cttgtttcaa tgcatctatt gttccattac cgataacttt
    47221 ttgctcaaat gcttgtttct ctgcagccaa accgacaaaa tccgtattgc tactcttcaa
    47281 ttccacacca atacccgtca ccgtaaaatc tggtttttct tcgatcctat actttgccat
    47341 ttctcccacc ctttctatta tattaagttc atcttacata aaattaaagg gaaatgacac
    47401 gattacgctc ttttttctag ggatattttt attttttaac tatttttttg ctttcactgc
    47461 aatccaaatc tcactgtaaa cattactgaa atcctctccc cattttgtaa aagagatctc
    47521 gggagcttcg actaactcat aatctgaaga aggaagccat tctgcataga ttttccccca
    47581 agtatcttgt aaagtttggg gaaatggccc tttattagga aaaatggccc aagtgtgttc
    47641 ttctatagca agcatttcta aatcagcgta cggattttct tttgtcgtag caaagccaat
    47701 catgtgcatc aaactgccct tttcttccaa gcgggctcca tcaaatccat aagaaacgtt
    47761 gattacttga tttggatata aatctcctaa cttatgcatc tcttcccttt gagtctccgt
    47821 gatcgtctgc gctaactttt gtatttcttg attgactcct tcaaatttga caggaacttt
    47881 tttcgccaca cctgccacat aaaactgttc tttcttttcg atacgaaatt ccatcgattt
    47941 tcctcctctg acatcaataa aaaatgtcaa gcgtggaaaa gatttttgta tgccgtatct
    48001 gctgatttct gaaggcagat atcctgacca atcacgaaaa gctcttgaaa aaccttcgac
    48061 tgtttcatat ccatatctaa acgccgtttc tgtcactctt gatccatcta ggagatcgcg
    48121 attagccaaa gccaatctac ggtttttgat atagtccatt agcgacatcc ctgcaataaa
    48181 cgtaaagatg cgttttaatt gatattcaga gattcctgta ttttcggcta ttattttata
    48241 ggaaagtcct tctgtcaaat gttcttcgat gtaatcgatc aattggttca gatctttaag
    48301 catatttatc ttcctccttg cttgcctttt tatcatatta tcaaagaaag tcaattactt
    48361 gatgaatcag gaaccaattt agtcagatgt agaaaatgtt gtatggatct aaagaaaatt
    48421 ctcaagcagc gtttcgtaac ggataattgg tattatctgc ctatctatgt tttaccttta
    48481 gaaaaataaa ttttggggaa gacacattct aagtaaacaa agcggtaaaa atatctttta
    48541 ttcccttagt taatccgctt actacctact gtacaaagca aattgttgtt caaactgctg
    48601 atcagaacgc tgcttggatt tttctttgcg atacatcata cctcttttat caattggaac
    48661 aattatttat ttctaacaaa atcacttcat ttttgtcaga taaataaaaa acaaaaaaag
    48721 ttccatcttt aaaacacgct attcttttac tttttctcac attctctaag aaaagaaaag
    48781 gagaatgaat ttttgacaat tcgagcaaaa gtgattatca aatatgtaaa atcagctact
    48841 tttttcttaa acgtttcttt atactaaata taaataagtg tttcatgaaa ggagaactag
    48901 atgaataatt ggcttgagta ttttcctgaa aacgttttgg aacgcggtta cagctatcat
    48961 ctgcacggtt ttgtccgtca tttgaactat acaagcaagt acttgtccgc aacagtttct
    49021 ggcacggaag attataaggt agtgatcact tgggatgaaa agaccaacat gacttgtgat
    49081 tgtctatatg ccatagaagg aaaaaaatgc aaacacatgg ctgctgtctt attcgcttac
    49141 gaagaacgtc caataaaaaa atccaactac tcactttccg aactctcgtc ccttgtttcc
    49201 tccgctagtt cctctcttgt acgggagctt ttaacagaga ttcttataga acatccgcaa
    49261 tttatcgaac gcttcaaagt taagatgcca tttcatgcaa taaattattc agataaatta
    49321 acaactatca tccataaata cgatcatatt atcaagaaaa acaaaaacag gaaaacagcg
    49381 aagttcatca tggagatgcg aaagttcatc caagaagcag ttgaatcgct cattcagcaa
    49441 aatgcctatc ttcccgcatt cgaattgatc aatgaagtga ttgctactct cgaaacattc
    49501 tattgggagc ctgaggatga acgaaccctt cttctgatag aggactgtta ttatttatgg
    49561 aaagaattat tagcagaagc acctcatgca gaaaaaaggc aaatgttctc ttggttcgtc
    49621 tgccaagtcg atcatactga cgcctcttat tcaaaacgct actccataaa aatcctgaaa
    49681 gaagactttc gggaaaaaga attttctaac caaaagaaaa aaatagataa aaaaactaaa
    49741 gaaacggtaa agaaagacga tttcaatgaa aaatagcaag taaacgataa caaccatcct
    49801 aaatccacaa gaaatacagc agaccttgct ttaaaaacac gaatcatgca aaggatgaag
    49861 taaagaagac ttaacgcgta cccaatatta gtcatttgac tattaggtac gcgttttgtt
    49921 ttataagtca tgacaaattt ccttcgttgc tgggtagatt ttccggcatt gttgatagat
    49981 tttatgatac ttttctacat tttgtaagag aggttccact gcatctgtat attggataaa
    50041 attctgacaa caactttcag gtgtgtcgaa ccactctaat ctttaaagat aaatattaaa
    50101 ataacgatta ataatattaa cagtctttat ttttcaccac caaaaaccta tctttgcata
    50161 tactaaatag acgtatatac acagataggt ttgtcttgtg aaaaataatg attatcctta
    50221 ccaaaaaatg tttgtttttc tacatgttcg tacttatcaa aaaatatgat ccttattgaa
    50281 attactggct atttatattc caacgacttc ttgtgttaat ttttgttatc tcatagtaaa
    50341 ttatgtttca ttttcactta atttagttgt cacgtgttcg tcaattcgta aaaacggtaa
    50401 atatataaac acacttgcgg ctataattaa tatttgtaaa acagctgctc gccagtctcc
    50461 ggctgttgct aaaaatcccg atataactgg tggcgtagtc caaggaattt gcactactac
    50521 atgattaatt aatcccacag cagttgcaaa atatgctact gtcaaagaaa aaatcggtgc
    50581 aagcacaaag ggaataatca gactgatatt aaatacaata ggcaatccaa aaataatagg
    50641 ttcgcttata ttgaatatag cgggagttac cgataattta gcaaagtcct tataatcttt
    50701 tctacgactg aagataaata ttgcaatcaa taaagcaatc gtatttcccg atccacccat
    50761 taccgcaaag gtatctttaa aggccatatt gataatatgt ggaatttgct ctttgtttgc
    50821 ataagctgcc atattttctt gcatattctg aatcaaaaac ggatctaaca atgaacctga
    50881 tattactgct tgatggatac caaatccaaa aaatagatta gcaatagatg taattaacaa
    50941 aaatcctggt aaaccagttg taattttact taatggctct gtaactatcg tggtaattag
    51001 cttatttata tccatattaa acaattgaat gattataaat gacaataaag caaacgaggt
    51061 aatcgtaata atgattggga ttaatacatt aaaagacttt aaaacagcgg gaggaatatt
    51121 tccggatagc tgaatctgta gtttcttatt attagaaagt ttaataaata attctgtagc
    51181 cgctaatcca acaaatatac ctacaaacat tcctgaagct cctgtatagg atataggtat
    51241 cacacccgtc acttcaacag ctttatccgc attttcagga gtaaacatca tctgcatagg
    51301 tgttaataca acaaatgtcg aaatagcaac taataccgct gcaatatgat ttgtataatt
    51361 tctgcttgca cacatatgat aagatactgc tgctacaact aataatgtag ttatgcttaa
    51421 tgtaccattg gcaattgaag taccaatttg ttgtaacgtg gtcaatgtac tagtatcgac
    51481 aatttccccc atgaatcctg ttggttctaa gatcactgaa ttaataagtg tcacaaatcc
    51541 tgctaacatc ataaatggca taaatgtagc aaacgcatct cgcaaagttc ttaaatggat
    51601 ctgattcccc aacttagtcg caactatacc aaatttttca aatacaatgt ccttcctgct
    51661 acttttgccc atattttttc tcctttatgc ttattgtaat cgattacttt ttccacccaa
    51721 ataatacatc acttatcaaa aaaagtaaat acttttaatt aaatatatat atctttttta
    51781 gtataaaaaa ataagctctg aaaaaataat tttcccgagc ttatttttca acaaaaacag
    51841 cttcaaaaac aaagtcttga tataaatgtc tcgataccga atactcgaaa ggtttaccag
    51901 acgatagagc aacaactttg tctatctcaa tcataaattc acctggatct atttttaata
    51961 tttttgcgtc aaattcattc gcagtatctc ctttgatacg tatgtgcgaa gtctttattt
    52021 ccagacccag ttcatttgtg atataagcat atacagattt ctttaaatgt tttggttcca
    52081 agcctggtat gactgctaat ggcatgaatg tttgctcaat cgagtatggt tgacaatcaa
    52141 taaaacggct tcgtacaata ttatatacat agtcttttac actgatactt aatttatcag
    52201 ctactttttt cgatggaagt tcaattgaga aagtatggat ttctgaatct acgtgttctt
    52261 caccaaccac gctaaacaaa ccttcgtttg gaccaagaac tcgtgagtta tcaattggtg
    52321 ttctgacgac ttcagtccca tacccacttc tacttcgcaa aactccttcg gaaacaagta
    52381 agtctacgcc tttctttact gttaacttgc ttgtatgata aataactgcc aattcatctc
    52441 ctgtaggaag tttctcacca attttatact ctccatttac aatttttttc tttatatcta
    52501 agtaaatttc catatacttc gcaatttttt tcaatggtga ccctccaatc aaaaacatat
    52561 cttcatctat actttaacat aaataaaccg ataaaatcca catcaaaatt atacacacaa
    52621 taaaaaagat atatatattt aaacaaaact atttacttta agttgtaagc ggtgttatca
    52681 ttaagtggaa acaggaggta aaaaaattat gacaactatg aaaaagctaa cttttccaga
    52741 tgatttttgg tggggttccg cttggtcagc tgagcaagca gaaggaaaag gagaaacagg
    52801 aaaagcagag actatctggg atcgctggtt taaagaacaa ccttaccggt tttatcaacg
    52861 aatcgattcc tctattacaa ccgatcacat ccatcaatat aaagaagata tagaactaat
    52921 gaaaaaaact gggcataact cctttcgcgt ttctatttct tgggcacgaa tgtttccaaa
    52981 tggcggtacc ggaaaagtaa atcccaaagc catttctttc tatcgaaaat tattttccga
    53041 aatgaataat aacggaatca aagtatttgc caacttatat cattttgaca tgcctgctac
    53101 tcttcaagat aaaggaggat gggaatcacg tgaagtagtt gatgcttatg ttcattacgc
    53161 tgaaacttgt tttaaagaat ttggtgactt agtttgtcat tggtttacct tcaatgaacc
    53221 acttgggcct attttaggta cttatcttga agattttcat tatccaaacc tcattgactt
    53281 taaacgcgga gcgcaagcag cattcttcac tatacttgca cacgcaaaag caatacaagt
    53341 atttaaagaa ctagctcttc ctagtaaaat aggcgttatt ctaaatttga gtcctacttt
    53401 tcctcgtagt caaaatcctg ctgatgtgaa agcagcagaa atcgctgatt tattttatac
    53461 gcggagcttt ttagatccta tggttaaagg gaatttttct aaaaagctta tcctgttatt
    53521 acaagaatat aatcagcttc ctgaagatta tacgaaagaa gatcttgtat gtatctacga
    53581 aaataccgct caaattcttg gactaaacta ttacgagcca cgtcgcgtca aatctcgttc
    53641 ttctatggtg gatacatcta gtccattttt accagagtgg tttttcgaac cacatatcat
    53701 gcctggacga cgaatgaacg aataccgggg atgggaaatt tacgaaaaag gaatttatga
    53761 tttgtgcatg gatatcaaga accattatgg aaacatcgaa gcatttatct cggagaacgg
    53821 aatgggcgtt gcggatgaag aacgtttcat ggatgataca gggcaaataa ttgatgatta
    53881 tcggattgag tatatcaaag atcatcttgc ttacttatgg aaggcaataa atgaaggatg
    53941 taacattaag gggtatcatc tttggacatt tattgattgc tggtcatgga tcaacgccta
    54001 taaaaaccga tatgggctgg tttcactcga ccttactact caaaaaagaa caattaaaaa
    54061 aagtggcgaa ttttacaagc aattaagtga tacaaatgga tttagatacg atgtagactt
    54121 gttagttgaa taatattcta aaattccact tgaagtgaac acattagaaa acaagaataa
    54181 tgagaaatac caataacaaa tactttttct tcatacttca tttatacttg tcagtataag
    54241 agactgtgac aaatgtagtg atcctcagaa gttaggtctg gaaatctaac ttgagaagat
    54301 ttttttaaac tacgtccagt cttttttatt tgtttaaaat tgaagttgac aagtcttcat
    54361 taaaaattta gaatattcac aagtttgacg acaattatga aaatttatgt cgtgctaaag
    54421 gagttttgtt attggatgaa aagttagata taaaaactgc gatcaaagac acgttaccta
    54481 ccgtttttgg ttatatcggt attggacttg catttggtat cgttgggaaa gctgccgggt
    54541 ttcatccgct ggtcgtcacg ttgatgtccc tgctgatcta tgctggttct gcccaattta
    54601 tcacggtcag catgcttgct agccatagtc cactgctctc catcgttctc tcgacctttc
    54661 tagtcaattc ccgaatgatt ctgatgagta tgacgattgc tccttatttc aagaaaaatc
    54721 ggctgcttca aaatctgctg attggcacat tgctgacaga tgaaagtttc gcactgggaa
    54781 tgaataaatt gaactatact ggacaaaagt taaactttcg ttggatgaat acagctaatt
    54841 ggatttctta tttgacgtgg gtgggttctt ctcttgttgg cgcactttta gggaatttta
    54901 ttactgatcc gaaaaagttt ggtttggatt tcgccatcgt cgctatgttt atcgggttac
    54961 tttatcttca agtcatttct gatagaaaca cctctaaacg attacagttg atcctgattg
    55021 gtctcacttt gattctggta tatgtcggac tgatttttat cccaagtaac ttagtgattt
    55081 tagttgtaac actgattggg tgcggattgg gggtgtggat caaacatgcc ttcttttgag
    55141 tttacattgc tgactatttt aggttgtact ttagcaactt ggctttctag gatcctacca
    55201 tttgtcttac tgaaaaaatt cgatttgccg caaccgttgc ttgagtattt aagttttgtc
    55261 ccgatcgtca ttatgtctgc tttatggttc agcagtctat ttacccaaaa tatcggacat
    55321 ctgccgcaga tcaatctcga aaatgctttg gcttcagttc ctacactttt agctgctatt
    55381 ctttcaaaaa gcttattggt gatcgtcttg gtaggaattc tttccctttc gttgattcgc
    55441 ttattataaa taaaaaaaca agagcttatg gcaaattact gtcatgcgct cttgttttta
    55501 tcaaagtcaa ataagaaaaa aatcggcgta ttcttgctta tccgttgaac ggaccactaa
    55561 caacgacttt tcctaatata tgtcctgttt ctacgtcttt ggttgcttgt ttcaagttct
    55621 tcgcattcat cccatctgaa tagaccttgc tcaatgtact gcggataatc ccttcatttg
    55681 ctaaagcagc aatgtgcgct aaagcttctc cttgcgtttc gatttcatag ttatagtctg
    55741 ttttagcgaa catatactcc cagtcgaagc tgatagattg gtttttccaa acacctatat
    55801 ctaacggctc tttgatccct acgatcgttc ccacatgtcc aaatggtcgg acaaggtgtt
    55861 tgatttgatc aaagtagcgg gtaatatcga ataatacagc gacatactct acttgatcga
    55921 ttcctaattc acgaaaactt ttacttaagt cgtgatgata atcgattgga tagtctacac
    55981 ctgttttttt cagccattca aaattcttcg gacttgcagt cgcgtagact tctaggccag
    56041 cccaatgcgc tagttgattc aaaatcgaac cgacgccccc agctccgttg atcactaaga
    56101 tttttttccc gcggttggca ttttcttctg gagtcagacc aaatttttca aataacaatt
    56161 cataagcggt caatgaggtc aacggcaagg ctgcggcttc ttcatctgaa agattttttg
    56221 gtgcaagagc gacaatacgt tcgtcaacca gttggtattc ttgattgctt cctgctcttg
    56281 tcgttgtacc tgcgtaaaaa acgcgatcgc cgacagaaaa tttttgcact tcatcaccta
    56341 cagcaacaac tttcccgact ccatcaaacc ctaagatacg taaagcattt cttatcccgt
    56401 tatcttggcg aagtttcgta tcgacaggat taacagatac tgcgttgact tttaccagaa
    56461 gatcccgtga actgggtaca ggtatctgtt ctttttcatc aataaagctt tttggatcat
    56521 cgatcgacaa cccttcataa aaaccgacta ccttcattaa ttccttttct gacatacgaa
    56581 ttcctcctta gcttcatcaa gttggagcat ccatacagtt ttcatttcaa tatatatagt
    56641 atgctatttg ttccactttt attcatcata attattctct tacttaaagt aaactatttg
    56701 cacttttttg gttaaaaaag aggttgcgac aagacttttg tcacaacctc ttttaaacgg
    56761 tgttcaatca actgaccctc ggtattcgct caaaaaacga caaaatatga ggagctattt
    56821 ttgtttggct gttcttatta cttgatgcag gacagctttt tcacgacctc taattcacgg
    56881 tgttcaagca agaaatcatt gttcactgaa aagcgttgga tgttcttttt caaaggtgtc
    56941 taagatctct cgtacttcat cagtagattt cgtattcatc aactgaactc gcaagtcatt
    57001 tgctcctgga aatcctttga tatagatttt aaagaaacga tgtagtcctg tgatggaacg
    57061 cgggatgatt tctgaataat gatcttgcag atctagttgc agacgaagta gtccgatcag
    57121 ttctttttct gtatgttccc tcggttcttt ttcaaatgca taaggattct tgaaaatccc
    57181 ccggccaatc atgatgccat ctacgccata tttttcggcc aattcttctc ctgtctggcg
    57241 atctgggata tctccgttga tcgtgatcag tgtttgcgga gcgatttggt cacgtaaagc
    57301 aatgatttta gggatgactt cccaatgtgc atctacttta ctcatctctt tacgcgtacg
    57361 caaatggaca gaaagattgg ctatatcttg atgaagtagg tgactgatcc attcttccat
    57421 ctcagacatt tccgtatagc cgatacgcgt cttgacgctg acaggcaaac cgccagcttt
    57481 agccgcttca atcaattgtg ccgctacttc tgggcgaagg atcaagccac tgccttttcc
    57541 acgttctgct acattaggga ctgggcagcc catgttgata tcgattcctt ggaagcccat
    57601 ttctgccata gcaatgctca tttctctaaa aaattctggc ttgtctcccc aaatatgggc
    57661 aaccatcggc tgttcatctt ctgtaaaggt caatcttcct cgtacactgt cttttccatc
    57721 tggatgacag aaactgtctg agtttgtaaa ctcagtaaag aagacatccg gtgctgctgc
    57781 atgctttacg acatggcgaa atacaacatc tgttacatct tccattggtg ctaaaacaaa
    57841 aaaaggcttt ggcagctctt tccaaaaatt agtagtcatt tatttgttac tctccattct
    57901 atcaagcagt gaagtcgcaa tctttctcaa aaacattgtc attatactag gaaacaaaaa
    57961 aagaagcaaa gtgaacagct taaaagatgt ttctgattga gcaaaaaaag actgtgacaa
    58021 aaatcttatc acaattcctt ttccggaata aatggtgttc aaaagcttgc atctgcggta
    58081 ataagtccaa ccaaacgaaa aataggagga gctatttttg tttggctgtt cttattactt
    58141 gatgcagaac agctttttca caacctctcc actaaacggt gttcaatcag ctgaccctcg
    58201 gtattagctc aacaaacgac aaaatatgag gaactatttt cccgtttgtt tctctaatac
    58261 tcaggtcaaa acgctgattt cacaacctct tttctaactt ctcaatcctc ttcctttatt
    58321 gatcaaatac caagtaacgg cgtacaaaac aacgatgaat agcacaagta cgatcatcga
    58381 tgttgctact ggcacatcga ttgttccaag gaatccgtaa cggaaaccga agatcatata
    58441 aacgatcgga ttgactttcg aaacagcttg ccaaaatggc ggcaacatag agatggcata
    58501 gaaaacgcca cctagataag ttaacggctg caagacaaat gtaggcacga tcgatacatc
    58561 gtcataagac tgagcaaaaa tcccgttgag cagtcctgct aacgaaaaca agattgccgt
    58621 catcaataat gtaatgatga ccatgaacca tgaatacaca tgaagtggta caaagaacaa
    58681 ggaaatgatc gttacgagag agccgacgag aatactgcga cccactccgc caatcacaaa
    58741 gccccaaatg atcacatgcg taggaacagg cgctaccaag atttcttcga tgtttttctg
    58801 gaatttttga gagaagaagg acgaagaaac gttggcatac gaactagtga tagcagacat
    58861 cataatcaaa ccaggcacga tgaattccat atatgaaaaa ccacccatgt caccgatccg
    58921 accaccgatc atttttccga aaataacaaa gtacaaggat gtcgtgatca caggcggaac
    58981 cagtgtttgg acccagatac gcaaatagcg gttcgtttcc ttgatagcta aactttttaa
    59041 tgcagtaaaa taaagattaa acatttttct cctccgtatg attattttct tctgtgattt
    59101 tcaaaaacag ttcttctaaa cgattcgact tattcctcat agaaagaact ttgattcctt
    59161 gtcttgtcag ctgatcgaag attccgttca ccccttgatt tcgttcaact tcgacagcga
    59221 ttgtctgttc atcttcaaat gtacaagcgt atccttcaat cacaggtttg gtctcatatg
    59281 gcgctaaatc aaagataaat gtttcaaatt gcagtttgga tagaagctct ttcatactag
    59341 tattctcgat cagttcacct gattggatga tcccgatgtt gcgacaaagc atttcagctt
    59401 cttctaaata atgcgtcgtc aaaatgatcg ttgtaccatt ttcgttcaat tctcggagaa
    59461 actcccacat ctcgcgtctc aattcaatat cgactcctgc tgttggttca tccaagatca
    59521 gcaaacgtgg ttcatgcatc aatgccctag caatcatcag tcttcgcttc attcccccgg
    59581 aaagcatacg tgcacggaca tttctctttt cccaaagatt ggactgcttc aaatattttt
    59641 cgctgcgttt catcgcttct ttgcgagaga caccgtagta gcctgcttga ttcacgacga
    59701 tttgctggac cgtttcaaag ggattgaaat tgaactcttg cgggactaat ccaatctgtt
    59761 gctttgctcg gactagatcc gtatccagat cataaccgaa gacattcact tttccagatg
    59821 ttttattgac taaagaagta atgattccga tcgttgtaga cttcccagct ccatttggtc
    59881 ctaatagcgc atagaaatct ccttctttca cggaaagatc gattcctcgc aatgcttcga
    59941 ccccacttcc ataaaccttt ttcaaattat ttatttcaag cgcatttgcc atttatttcc
    60001 tatctcctta tagacatgat tctttattgt atcatggaat acagcagatg aaaaaacaac
    60061 ttggttccag cgaaaaatca ggttgctggg ctcaggaaaa tctcctaatg aaagacatca
    60121 atcggacgaa gtcagacaac cttttcagaa aaaacaaatc gaagataaag gattactatt
    60181 catatgtgca acaaaaggag cgtgagacaa aagtaaagaa cacttttgtc tcacgctcta
    60241 aacacgtata aacggcggaa gcaaaagcca agatttttga tccaataaat actttcgatc
    60301 acttcgccta tcccaataca tgccactgcc gcttttcatc aaataacgcg gcttccgttt
    60361 ttgcggtttc tactaaagtc tctgggtaat ccaaaacttt cagcaaggca atcgcatttc
    60421 gggtccttga aggtccttct tttaatttga aatcaaaact gattcctttt ccttctgtta
    60481 cttgttcttc aaagtggaca ttctcacaat aattctttaa aatctctgtc aattcgatat
    60541 catgtgtggc gacaaatgct aaagatggat actccgcaag ccaccgaacg actgaagcgg
    60601 aagaagcaat ccgttcgatc gtatttgtcc cttttaaaat ctcatctacg aagcagtagc
    60661 agcgttcttt ggaagccact tggtccaaca aacgtttgat cgatttgatt tctgaaacaa
    60721 aataactgtc gccttcaaat aaatcatctt cgattgccat ggaagtcaac acatgtccag
    60781 gttgcagggt aaactgttct gcaatcgctg tttggatcgt ctgtgctaga atacagctga
    60841 tggctatact tttgacatac gtagattttc ctgatgcatt ggaacccgtg actaatgtat
    60901 tcttctgcca gttgaccgga ttcactaccg cttcttttaa caatggatga tagatatctt
    60961 tcgctgtcac accgccctca gtaaactctg gtcggcaagt gatgggcata taagtacggt
    61021 aattcaatat tgcagcggct acttctaatt ctcccagcaa ttcccacagc ttgatggctt
    61081 cagttgaatg cttttctaat ttagtgagaa cgaaatgata ggagataaat ggcagcatga
    61141 acatgatgtt gacatattca aaaatcaact ctgcttcact cccactcttc atacgaaatg
    61201 aaaaacctaa tttagggatg tctcttaatg gtttagtttg ctgtttcagc tcttcttgaa
    61261 gtggtgtcgg cagttttgct agctgattgg cggctgaaat cgttgaaacc aaataactca
    61321 tgctattcag ctctgtttct agtgtttgtt tcttcactag ataatagacc gtattgaata
    61381 ctaacccacc gattgccaaa tagattccta gtacttgtcc taaaagaagc aaacccaaac
    61441 ccaccagcgg aagcaagcca agaaaaataa ataaacctac gcgtccaatc tttttacttt
    61501 ttccatccgc tagatattgt tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt
    61561 gatattggat tttttctctc agttgaggat tttcctgata aaaagcaatc agtttttcta
    61621 actgctgatc ttcaccaaaa tcaaagctgc gtaaacgttg atacaacgct tctgaaccta
    61681 cactagaata ggtactgttg attccttcga atacttcgaa catatccagg tcataccaag
    61741 taagatcatc gatttcgcta tcccatgaac ggaacttctt ctccgtgagc catgcttcct
    61801 tcaagctttc ttctttatca aatctcggtt gataaggaat tttttcccat ttgctacgaa
    61861 ctgtttcctt taatttcaaa cgtgaaaaaa tgtctaaagc aactaataaa ataacagctg
    61921 caataataat taaaacgata aattctcttt gacccatatc cctctccgtt cctttatttg
    61981 ttagctttag tatagcactg ttgcgctatt tgaaaagagg gtaaaaaaac acctttcaaa
    62041 ataaaaggtg tttttttctt gtatattaca tatttatctc tcatttatca aaattgacaa
    62101 ataatcatag ggaggaattg ttgttaattc ttgtttattc tccagtgcat tgacaactgt
    62161 cccaagggaa aggatagcct caggtactat tttttcttgt tctgttggat tagctaagcg
    62221 aagaacaaat ccttgttcat gaaaataaga aggataaatc gatgatacaa ttaagtcttc
    62281 aggtaattca atcaatgaaa atttacgagg aacatcaagt tcattttgta atggccaaat
    62341 cttgttatct aacctgtgaa taaatacatt cagtttctgc ttttgataag aaatagattg
    62401 ttctaaccgt ttttctgcct gttttgccac tttgaactca ttaaatcttc cttcttctac
    62461 attaaatcca aaagtgactt tatactcacc tatctcttga gctagcggtg tttccatcat
    62521 gacatgccct tcatttgtcg tatctcctga agctcgccca ggtcgccaag caagattagg
    62581 ttttccaagt tcccctgttg ttgaaaataa ggttatgatt aattgatttt ctatacgttc
    62641 atactctttt aaaccatctg cataaaacgt aaaataatga tcattttctg ccacagagac
    62701 actcttatcg aatatttcta aattaacagg tttctctacc atagtttctg accaattcgg
    62761 aggaatgaca tcaggggtat tttcaataaa tccgttttga atttgtgcaa ttgatttttc
    62821 agatttatct aaaacattaa ttgctaagcg catacgatgc gagtaaacag tattatgaat
    62881 tttgagtgtg ccttcaacga tttgactttc tcccagactg aacgatattt cataagatat
    62941 ttcttccatt tcgggttttt cagataaacg atcttttaaa tctttaggaa gttgagcttt
    63001 tccgtaaaca actaatgttt cttgtaaaga atctttatat actttagctg tttctaattt
    63061 tagagatagt tctgtatctc cttctaatgg tgaataatca tacgtatcgc catcatttgc
    63121 tgaatcgatc aaatgaacga aatcaagata ttgtctatct ccaactatca aattcaattg
    63181 cccatcttta aaagaaagtt tatatttatt gttacttatc tcagttttgt ctatctcgat
    63241 tgctgtttct aatttttcat tatttttctc aaattcaaca acagtgtatc ctagtgctgg
    63301 cacatttaca tttattttta tgtcaagttc ataataagct ggttcatcaa aatattcgaa
    63361 acctgtagca atcatccgat aagcattttt ccgttctgga aaataaactt ctttttcaat
    63421 gatattatag ggactacctt tgaagtgtat tttctttgaa tcagctacta catgcacgat
    63481 tttcgatcca ctataattct cagtcgttgt gttgaaaaca aggacttcat tcgattttag
    63541 ctttaatgca tcagccatcc gttttacaat aaggttttcg attccgtcag ctatctcatt
    63601 agcttctttg attcgatgga aaatatcttc cgcaacatta tctgaaacac agccaccaat
    63661 actatcatga gcctggtttt gcaaaatctt tttccataac cgacgaagta ggcctttact
    63721 gatatggata ccatttcttt ctgcaatcag catgagcggc tcaactcgtt ttagaatttt
    63781 ttgttccaat ttaaaatttt ctattttcat ttttgttctt actgagccaa tagaacgatg
    63841 aacacgagag taaaccggct gacgaagttc acctttatat tcaggtaatt cttttttgtt
    63901 tctgataact tctacataag aaggataatc tgaaataata ttgtggaatt tactgtattt
    63961 attcaacttc tctacgactt gatcaaaatt taaaatcatt gacttttgat ctacacccga
    64021 aggtactaaa atatctttgt tttttccttg catatgaagc atttcaactg cttcatccaa
    64081 cttttctttt gcaaattcag gaatatcttt aattgcgtct aaggtcatca ttccagtcat
    64141 ataaccaaat ggaaaattca tggcataaac aaatttatct cccaatcctt tccagataaa
    64201 ataaggagat ggaaccatcg tttcaaagtt taatcctcgc caacacatga aattatcgat
    64261 ttctacttga tgcaaaagtg taggcaaatt cgcattgaac ccaaacgtgt caggcaaata
    64321 ccctaccatc attggatctc catatttaag gatcgtatca ctgattccaa tcattaagtt
    64381 tcttaaaatt gattcagcat ccactaataa ggcatctgtt tgtgcatacc acggtcccac
    64441 gaatagttgt cctgttttca tcagtcgttg gataacctta agcttttgcg gattgatctc
    64501 caaatactca tcgacgattg aagtttgtcc atctaaacaa aagtttactt tagggttcct
    64561 ttccaattca tctagaactt cagtaaagac ctgatcagac aatacgatgg catcttcatt
    64621 tgtaaaatac cattctctgt cccagtgcgt gtgttgaatt atatgtgcat ttaccatatc
    64681 agattctcct actttccttc ttctactgaa tttacttgtt gttctttttt atacttgatg
    64741 gattttagtg cattgaccat taacgctgta accactcccc caataacaat tgatactaaa
    64801 tataaaggta tattcgtaac aaaaggaatt gccataaagg ttgaaagcat tgtttcttga
    64861 gtaacaccaa aaaatccatt tagaccacat gctactgcag tgcccaccac gatgcttggt
    64921 attactcgta aaggatcttt cacggcaaac gggatcgtcc cttcagtaat ccccacaagg
    64981 cccataatca tagctgtctt tgcattatct cgttccgatt catcataaag ttttttgttt
    65041 aaaattgttg ctaaaaacat tccaaatggc ggaatagcaa ttcctaataa catggctgta
    65101 ctaggtccaa agcttccgct tgaaaaagaa gcaaccccaa aagcatatgc gattttattg
    65161 ataggtcctc ccatatcaaa cgccatcatt cctcctaaaa tagccgacat caaagcagca
    65221 tttgctcctg acatgccttc tagccaatta gtcagtcctg ttgtcattgc ttgaataggc
    65281 gtagctagta cataccataa tatgattcca acaactaatg tagtaacaaa aggaatcagc
    65341 ataattgatt ttagactaat aacttgcatc ggtactttta cttttttcaa tgcattagct
    65401 aaatagccac aagctaatcc agcaaccatt cctccaataa atcccatacc aagattttga
    65461 cacatcatcc cagtgataaa agctggtgct agaccgggac ggtcagcaat tgaatatgcg
    65521 atataggctg aaatcatcgg tacgataaac tgtaatcccg tctgaccaat cattcgcagg
    65581 actccccaga atgtatccgt ctggtcccaa acacctgtgc caccaaaaat gactgcaata
    65641 gaagttagta accctgctgc tacgacaagc gggatcatat aggaaacccc actttggaaa
    65701 tgatttagaa tttctcttcc ttgtttcttg aattccatta gtaactcccc cacgatatat
    65761 tttttatttg ttaattaatg caattgcttc atcaatcgtc tcttcaccat cttttactac
    65821 ctctgaggtc cctactgtta aaatcggttt accgtcaaag cgacctcgtt ctgaaacatt
    65881 tgtatctact gcaaatatga caacatctgc ctcggaaaca tccgaaattg aaagtttgtt
    65941 ttctatcccc atagccccct gtgtttctac tttaatatct aaccctttct tcttcgcaaa
    66001 cttttctaaa ttagcttttg ccatataagt atgggcaatc cctgcgatac atgctgttac
    66061 tgctactatt tttgtcatat gaaattcctc cttttaaaat gatagagctt ttaccaattc
    66121 ttttttattt ctcgaatctt ttattctttt aacaaactcg tcatccatca atcttccaga
    66181 taattctgct aaaatacgta aatgattagt acctttatca gtgtctttta ttgctaacaa
    66241 aaagacgaga tcaactggtt gatcatctaa tgcgccccat tcaacagacc gctttaactt
    66301 ggctacagcc actgttgatt caattactgc taggcttttg ccatgaggaa tggcgatatt
    66361 tttcccaatt cctgtggtca tatggttttc tctgtcaaat acgtcttttt gaaattgttt
    66421 gtggtcagac acaaacccat tagtctctaa caatttcgat aatttttcga ctacactttt
    66481 tttatcagat gcatttaaat ctatcactat attatttata ttgatttttt cactgatcat
    66541 ttataagcct tctttcaata tataaactaa tttttcaaac gacgaactcg tttttaaatt
    66601 tgctaataac tcatgattcg aagcgatttc attgaatgtt tcataaattt tattcaattc
    66661 aggttttact ttttcattaa gtgcaaaaaa gaaaacagaa tgaacaagtg tcccatccca
    66721 atcaattcct tctggattaa cgtagacaca gattactggc ttttttataa aatctacttc
    66781 gatatgcggc atagcaaaat cattcatcgc tgttgaagat agtttttctc ttttgattgc
    66841 tccctctagt atcccttctt tcgcgtaatt ttcttttacc aattttttgg taattatatt
    66901 taaaacgttc acttgattat cctttatttg gtgggtaaaa aagcaaaatc gtttatctaa
    66961 taaatttaga aaagcatctt ctgtttgttc atttaactgt agatactgtt ttacttttct
    67021 gacatctgcc cctaacatca aaggactaac aacaataaca ggaaaatttg tattttcaat
    67081 cggaatcgtg cttataacaa gttcatcagt gacttttcta tcttgtagtt cattgatgct
    67141 tagtacatct tctatctcaa ccatatctgc aaaaccgtta tttattcttt gctctaataa
    67201 ttttgatgtt ccatatccgc tactacaaac taatatcact ttcgttttgt caggtttgta
    67261 acgatccaaa agtgattgaa tatggagtgt tacgtaagcg atttcatctt cattaaaatg
    67321 tatacagaat ctctcttcga tttcctctaa taaatctaca cttatcataa atgacctttt
    67381 aaaagaatat ttgattttgt ccgtataagg gttatagata tttactccca atttgagtct
    67441 tttaactgct gcattgagat gtaatactag attattgatc aattcttcat caggataaaa
    67501 ttcatttaat ttaattctta ctaactcttg tagctcaaca cccatatcta aataggaaag
    67561 cttcgtttga tctaagtcgt gattcatagc atttttttca atcgaagtaa tgtgaatgtc
    67621 aacataagct tgttcatcta ttggcacaat aattgaaaat gctttttcaa tcattttgat
    67681 taaaataagt gtattctttg agatttcttc ttcagaatta ttactacgtg ataagaaatt
    67741 gcttgtttca atcctttcta tcgcaatagc aaggtggata gctaaagttt gaaattcata
    67801 atctgtaaat ttcaattgtg tcttattcat gtatcgatta agcaattcgg ctactttttt
    67861 caatatgtcc ttatttaaga aattattcgc ttcaccaatg aaattgatat tcaagtctaa
    67921 gagatctgtt ttactgttag atgctgtaaa gccaccccaa taatagttca caacttctga
    67981 catcaacctt cttttacttt tttcatcagc tttgatgcgc acgccatttc gatctgaaac
    68041 taaggacatc ccatgcttgt ttagtctttt tctaacatct ttcattgtgc tttctaccgt
    68101 cgacctgctc acgtataatt cgtcagcaag attttgaatc tttagagaat cattagtatt
    68161 caataattta gcaaacacat aagttagacg gtcctccgga gagtctgcga tattgatttt
    68221 atgactggat aataaatttc gaagtgtttc tttttttcca ataagcgaaa cgcctttttt
    68281 aggttgaacc aacatttgta catctggcat tttttggatt atttctttca aaattaaaat
    68341 atctttgcta attgttttcg tagatacata taattgttct gataattctt tgtaagttgt
    68401 gtgctcattt tcaatcaaaa agtatagtat tttcatttgc cgttcgctaa attcgatgcc
    68461 cattatcttc acctcctgaa tacagcttaa gtgtacaatt attatctcta ttttcataca
    68521 gaagaaagtt cttgattaat gtagaagttt ctaatattct tgattatttc aaatcaataa
    68581 aaaagcctgc aatatttata tcacaggctt ttttctctat taaatatata taagataata
    68641 catttttcta ctagttctca ctaatcttgt ataattaaac cctccgcaac ttgacggaga
    68701 tggagaagat gcccccgtct aatctagcgg tcatctctcc tcccattcct tccaccaatt
    68761 tttttgacag gtaaagcccg attccgctag attccgtatt tgtgcggctg gtattttcgg
    68821 tataaaaacg ctggaagact ttttcaacag aggtttgcgt tcctggtttg ataggattgg
    68881 ccactgttaa tcgaatgaat ggatcctctt ttgaaaatgt cacctttgct tgtccatctg
    68941 cataacgcaa taaattctgt atgatatttt gcagcactcg cagcaacatg agcggatctg
    69001 ctaatacagt tgtatttatc gagtgttcag cgaacgctac ctcgatattt ttctcagaaa
    69061 attgttcata aaaagagaaa aatacttctt ccacctcttt agaaaaagaa agcgtatgga
    69121 gatccatttc tttttgcttc gtctctattc gagcaagatc ataaaactga tccgtcatac
    69181 tgagtaatct tgcaacagat tgtttgatga tcgttaaata cttctcccgt ttctccgtat
    69241 cctctacctg ttccagtaat tgtacataac cgttaatagc agtcaaagga gttctgagat
    69301 catgagaaag gccgacgatc gatagtctga tgttttcttc catttcttga aatgcttgtc
    69361 ctttttgttc attttcatcc aaccatgtat tcagtgcatc tactaggtcc attagattct
    69421 tttctcgaaa ttcgactgaa agacgaccac catattcttg tcgttcagaa agagtggcga
    69481 ttttcttagt taatctcttg atttcccttt gcaggaagaa aataaaactt cccataaaga
    69541 taacaacgag aagcaacagc catttaatca aatctaaacc ccactcccca caccgtatga
    69601 atatacacag catgtgcctt tgctagcttc cctcgaagat tggaaatatg catattcact
    69661 gttttctcac tatcaaaata tggttcttgc caaactgttt cataaagatt tgctcgcgaa
    69721 aatacttttt tcggatgttc taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa
    69781 tggacagcca caccattcac atttacatcc ctcgactctt tgtccagtaa gatttccttg
    69841 taatagatgc gttgcgacag atcttttact tggacagaag tctgatgacg aagttggatg
    69901 ccgattcgta acaaaagttc ttcgatatca aatggtttcg tcacatagtc atccgctcct
    69961 gctgccaaca aggaaacttt atctctttga tcgctttttg ctgaaagaac gatgatcgga
    70021 acattcgatg tctgtcggat ttctgctaac aatgcttcac ctgaaagccc tggaagcatg
    70081 agatctagaa ggatcaaatc gacaggatat gtgcttaaca ataattttcc ttccgtacct
    70141 gaataagcat caagaagttt gtatctctgt tcaagaacct cctccagtaa ggaatgaaca
    70201 gcttcatcgt cttcgataat caaaatagtt tccagcagga ccacctactt aatgtcagat
    70261 ttttggaaaa taaacattcc tagagctgat gataccacga ttgttactag actgaccaga
    70321 atcattttcg gtgcttgcga ataagttgct tgttgcgcaa agtccgtata catgagccac
    70381 gtttccgtaa accactccgt tagaaattcc aagcctttga tttttgcgaa aacaccggga
    70441 atgaaggccg ttcccatgat ataaagaaaa gaaagaagca aactgacact ggtacttcta
    70501 gtgatgaatg tcaaagccac tggaacagat aatgtcccta atgtcagcag aagcaataca
    70561 ggaaatactt ttagaacata atttccatag tttttgattc cctcaacttc accaaatccg
    70621 aaagcaagtg tgtaagcaag catggctagt cccgtgatca aaaccacgcc aagtgttgtg
    70681 atcaaaagcg taacgagaag tttcgacaca taataagtca ttcgattccg tcctaaagat
    70741 aacgtattgc gaatcgtacc gttttgaaat tcttccccaa tataaaagca cgcaaatgct
    70801 gcgaaagcca gaagaatcca tgcagccatt ttttctacca ttaaaatccc tgttgcaccg
    70861 ttgatgactg tatccgttgc ttggtttaat tcattgccgt attttgtatg catataccat
    70921 tcgttccaag aataaaaaag cggaagtacg accatcagtc ctagtgagac ccacatttta
    70981 cggctcttcc atacttttat tttttcagca gttaatagat taaacatgtg gattgcctcc
    71041 agttaattgt aagaaataat cttccagttt ttgcccaact aggtgaatac catccacagg
    71101 aacttttgct tctaccaatg cttgattgat ggctgctact tggtcaattc cttcaaaaag
    71161 ctggataaca cggctagatt gtacaaaata atccctataa ccaagagagt cgagaaccgt
    71221 tactgcttgt tccgtcgccg aagtgtcaat ttttataaat tgacgagatt cttgtgccaa
    71281 ttcttctttc gataattctt tgatcaagtg tccttcatgc aaaataccat agtgagtggc
    71341 gatctgtgac aattcatcta gcaagtggct agaaagcaag acggtgatgc cccgttcttt
    71401 taccaaacgt tggatgattt ctcgcatttc tgccatccct gctggatcca tcccattcgt
    71461 cggttcatcc aaaatcaaaa attctggatt cgtgatcagt gcatttgcaa tagctaaacg
    71521 ctggcgcata cctaaagaga aattctttgc tttctttttc cctgtatttt ccaatcgcat
    71581 cattttcagc aggtcttcga tttctctatc cgacacaccg ccgttcgctg cttggatacg
    71641 taggttatct cttgcagtta attctggata aagagcaggg gtttcaatcg attgacccat
    71701 acgtcgtctt gctgcctgca aatccgtcgt tccaaataat tcgatcgaac cttcatcaat
    71761 cgagatcaaa cccataatag ttctcataaa ggtagactta cccgctccat tttccccaat
    71821 caatccatag atcattccac gtttgatttc gattgatact ttatctaatg ctttggcagc
    71881 accgtatttt ttggttatac cagttgcttt caagaccgtt tcatttccaa aatccatact
    71941 tatccttctt tcttattgat gagtgaagta tagttgacgg gtataaagaa agcagccaga
    72001 aatgtataaa gaaagtgtaa attttccaat tgaatgtcaa aaaaaacaat cggacaatac
    72061 gtgtctttcc tattatcagg cagtttgtta tacgcttgta tcagtttcct gattctttct
    72121 tttcgaccaa agtcgtttct ctgtattcct cttcactgaa aatttttgct tctttcagat
    72181 caagcttgag taattttacc agaccggtta taaggataac tatagcaaga ctccctccca
    72241 gaaaaattag actgtctcgc agacgtggtt gcgttgtctt ccaatcaaag agcgcaccaa
    72301 acagtgctaa tccaagtgga ctggccacca tggtaatcgt tgttatcgtt gacataagtc
    72361 gtccttgtat atgcgttgga acttctcgct gaagccagac catataaaaa gcaaaagaaa
    72421 acattaatcc ttaaaaacgg acttatgaaa aataatacat gccgtttggg atttacaatt
    72481 agctaccaaa taagaggtta tgacaaaaga cttttcacaa tcccttcttc cgaataaacg
    72541 gtgttctcct gccaactcct cggtcacaag tcacaatatt tatcaaacat gagaagcaat
    72601 ttttgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tcagaagcgg
    72661 ataaataata ttgtttgatg atactttatc tttttcccgt ttgtttatag atcgaatgat
    72721 attatagacc aagaatccta cctattaaca tagctaaaaa cacaaaaaag gcactttcca
    72781 aattgtggaa agtgccagaa aagttaggat taaggtaact gcgctcagca ttgcttcgcc
    72841 cagtacgatt ctcgtaactc gtgaactcga acgataatcg caattaacgt tttgagaact
    72901 gtgaagcttt acgggctttc ttaagacctg gttttttctt cgtatcattg aataagtttg
    72961 aaaaaccttg atttataaag gttttcccgt aaatatattt tattatattt gattaaattt
    73021 gaaatgtttg tgttctaaaa tgtgttctaa tttaaaggca gtatatttcg tattttagat
    73081 taaattttta ggctcattca ttctcaaatc cattctattc agtcaataaa aattttaaaa
    73141 agactttata aacaaagatg ttcaagcgag catcttattt ttttgtgctt aatttgaaag
    73201 gagaacattt catgtataaa aaacaaaaaa agaaattatg tgtattaact attttgagtt
    73261 tggctgttca agcaattgtt ggagcaattg ctcctacgat tacttttgct gatgaaatta
    73321 cccatccaca aacggtaacc gtagaactag atttagcaca tcaatatgct gttgaaggaa
    73381 cttttagtga tggtcgtcca atgtcagaag tcactgttcc gcattatgca gtgtacaacg
    73441 gctttaaaca agatattttc tgtattgaac caggagtccc gatttacaat gagttcactc
    73501 ctggctatga gaaaaacccg ttaccagata tgtccgataa agccaaatta gtttccgttt
    73561 tatggaaaaa agtaggtaca gatgcagata ctcatattgt ggcacagaag atgatctggc
    73621 aagaagttaa tgggtatacc cttcactcaa taaaacgatc agatggtagt gccgtaaata
    73681 tcgcagccat tgaggcaaaa ataaatcaag ccattgacga ttatcagaag aaaccaacct
    73741 tccataatag tacggctaaa acagtattag ggcaatcgac tactgtgacg gatacgaata
    73801 atctgaattt gtcagagttc gatgaggttg tggaaaatgc cgcaaacatt gattatcgtg
    73861 tgaatggtaa tcagttgata atcaccccaa atgccaattc aaaagaaagt ggtgtgctga
    73921 cgcttaagaa atctgctggt accggaacac ctgtcgccta taaaaaggct ggccaacaga
    73981 ctttaatggc cggggcgatt gataaaccta atacctacac aatcaaaatt gatgtggaaa
    74041 cggagggttc tttaaagatc aaaaaagtcg ataaagaatc gggtgatgtt gtaccaggaa
    74101 cggttttcca tttagacttt ggaaaaactt tacctgcaaa agacgtgact actgacaaag
    74161 aaggcattgc tacattggat gagattcctc atggtacaaa agtaaccatt accgaaaaat
    74221 cagtaccggc gccttatacg attgatacca cccccatgac taccaccatt aaagcaggcg
    74281 aaaccattta cgtgacttca aaaaacgcac gggaaaaagg gcaaatcatt ctggataaaa
    74341 gcggagttga aacagggagt gatctttgga atgacaatta ttccttagct ggtaatacgt
    74401 ttgccattcg caaagacagt ccaaccggtg aaatcgttca agaaatgacc acggatgaaa
    74461 acggtcatgc ggaaacacca aaagagattg ctaatgcgtt ggaattggga acctattatg
    74521 tgaccgaaac taaagctagt catgggttcg tgaatacgtt caaacctgta aaagtcgaat
    74581 tgaagtatgc caatcaaacc gtagcccctg ttaccagtaa cgtaaaaggg caaaatcaag
    74641 aagtcactgg cgaaaccact ttgacgaaag aagacaaaga tactggggat aaagcacaag
    74701 gtaaggcagt ctttgagggt gctgaataca ccttgtttac tgctaaggat ggaaaagctg
    74761 ttaaatggag tgaggctttt aaaccagagt tagcgaaggg aacgaaaggt tctgatgaaa
    74821 cggtcacttt gactttagac gaaaagaacc aagttgccgt taaacattta gctatcaacg
    74881 agtattattg ccaagaaaca aaagcgcccg aaggatatag ccttgatgaa acaaagtatc
    74941 ctgtatccat caaaaaggtg gatgatagcg aaaaaaatgc cgtgattacc cgaaatgtta
    75001 cggcaaaaga acaagtgatt cgctttggct ttgatttctt taaatttgct ggatcagctg
    75061 cgggcactac cgaaactggc ttcaatgatc tgacctttaa agtgtcgcca ttggaaggga
    75121 ccaatgaaat cacaggtgcc gaagatgaag cgaccacagc ttataacgag caattagggt
    75181 ttgatggtta tggcaagttt gaaaatcttc cttatgggga ttatttactt gaagaagtag
    75241 aagccccaga aggttttcaa aagattacgc cattagaaat ccgttctact tttaaggaaa
    75301 acaaagaaga ctttgtgaag agtgagtatg tctttaccat taccgaacaa gaccaaaaac
    75361 aaccaattaa aacggtgacc gttccttacg agaagctgac gaacaaagca ttttctgtta
    75421 gtttgaaccg tttaatgctc tatgatttgc ctgaggaaga agatagttta acttctcttg
    75481 cgacttggaa agacggaaac aaagaattaa cttctctgga ttctaccgag ctagttgata
    75541 aattgagtta caatctacat gaaatcaaag aagactggta tgtggtagcg caagccattg
    75601 atgtggatgc gacaaaagct gcccaagaaa aagatgaaaa agccaaacca gtggtgattg
    75661 cagaaacaag cgcaacgttg gcgaacaaag agaaaacagg aacttggaaa attcagcata
    75721 aattaaccgc cgaacaagtt ttaaataaaa ctattgtctt attcaactat gtgtatgaaa
    75781 ataaggaagc ttttgaagca ggcgataagc cagtagcgaa ggatgttagc ttgaataacc
    75841 aagcccaaac tgtcagttgt acagtggaac accatgtttc tatccaaaca aaggcccacc
    75901 tagaaaacgg ttctcagacc tttactcatg gtgatgtggt ggatatgttt gatgatgtgt
    75961 cgattactca tgatgtactg gatggctcaa aagaagcttt cgaaacaatt ctgtatgctt
    76021 tattaccgga tggtacaaac aaagaaattt ggaaatctgg caagattgat tatgaagtaa
    76081 atgataaaga attcaccaaa actgtgcttg cgaaaaaagt agataccgga aaatatccag
    76141 aaggaaccaa gtttactttt gcggaaatca attacgataa agatgggaat atcaatggaa
    76201 aacacaatga agatttgaaa gaaaaatctc aaaccttaac accaaaagaa gttccaacca
    76261 tactaagtac gccgaaacaa ccggaaacac caactgttcc aagtggctct caagaatcta
    76321 gtcccacagt gaagaccttc cctcaaaccg gggagaaaaa ttccaatgtt ttactgttca
    76381 ttggttttac tttgattttt gcgacggcgg gctattattt ctggaatcgc cggaactaag
    76441 gtgatgagat gatacaagta aatcctaaga accaacgtgc gcgaccgcct cctaaaaaag
    76501 tagtcgcgct atttttgtat ccaaaactaa caatgaaaag aggaaaagaa gatggaattg
    76561 aaatttgtcg tgccagatat ggctgaaacc tttggaaagt taagttatgc cggtgaagga
    76621 gaaattataa cagaaggata tggacggaat actacggtga ttggtcgcag ttatcatttg
    76681 tattccagta agcaacgggc cgatgatatt gaggtggtag tagctgcgga agccggtgaa
    76741 aaggattttg atcaagacca accgctaaaa gccgtgaatc cccatttggt tgccaaaggc
    76801 tatgagattg agaatcgtgg gtttactgat tacgtgttgt atgttgatga tttagtgaaa
    76861 gcataggagg aaaagaagat gagattaaca gaaggtattg tcgtagattc aggtttaaca
    76921 tttgggaagt tgcgtttttc cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga
    76981 acaattggta atgaggtaaa agaacgaacc tataatttaa aatcctctgc acaagggcga
    77041 atgattcaag ttagtatccc agctaatgta cccttacgcg agtttgctta tgatgcagag
    77101 gtagagttgg tcaatccaat cgtggatacc gttgccaatt atgtttttcg agaaggaact
    77161 accgttaatt ggttcattaa ggcggatgat ttagtcttga agcggcagcc gaatcaagga
    77221 aatcctacga accaaaatga aagaaagaaa taggtgaaga ttatggaaat taatgttgaa
    77281 catattttag attgtctcga tcaatatgga aaaggcgagc tgactgagga acaactcgtt
    77341 aaagcattaa cctctgatga aaaaatgttt ctgattatac atcaaggttt acttggagaa
    77401 aatagcgaca gtgaagaaga ctctgatgta ctagactggt taggagaaga agagtctttc
    77461 tttatagttg tcgaagtaaa tgaaaactta tgtcggcagg cagaatccat tttggaagaa
    77521 attggtgtgg agatgccgga tgctattgaa ggctttttaa atcaattggt tgaaacgaaa
    77581 caactcccct cctcgtagca gtaaatgact agcataactt tttgaaattg cctaatgaaa
    77641 tcctattggg ctttttcgat tggaggtgga aaccatcaaa atgtacaaag gacatcgcat
    77701 acgcgcagga gatcagcact tggtttatca ctttgttctt ggctggctac tcgctctgtt
    77761 catcggttgg atgagcgtct tttattttca agagtttaga caatttgata tttctaagct
    77821 atcactttct actattgaaa tcgtttggtc tataaaagat ttagtatgtc tgcttggaag
    77881 tctcgctttt tcaggagcta tgatattgct ttatattcac ttttttcttg atcattggcg
    77941 aagcttgtgg catcgacaaa agctagctcg gatgattcta gagaaccatt ggtatgaagt
    78001 gaaacaaact caaagtgaag gctttttcaa agatttgaat agtagccgaa ccagagagac
    78061 tatcagttac ttccccaaaa tctgttatcg aatgaaagat ggattactgt ctattcgcgt
    78121 tcaaatttca cttgggaaat accaagatca gcttttaaaa ttggaaaaga agttagaaag
    78181 cggactgtat tgtgagttag tagaaaagga actcaaagac tcctatgtgg agtatacttt
    78241 actgtatgat atgatcgcca atcgaattgg gatagacgaa gtagtggcag aaaatgggac
    78301 tctgcgattg atgaaaaatc aagtatgggc ttatgattct ttaccccata tgttaatcgc
    78361 tggtggcacg ggtggaggga agacctattt cctcctcacc attatcgaag cactattgaa
    78421 gtcagatgca gaattgttta tcctcgatcc caaaaatgca gatttagctg atttaggtac
    78481 ggtgatgcct catgtttatt cacaaaagga agaaatttct gcttgtgtgg aagatttcta
    78541 tgaacgtatg atggctcgta gcaaggcaat gaaagaaatg tctaactaca aaacaggaga
    78601 gaattatgcc tatcttggac ttccacccaa ctttttaatc tttgatgaat acgtggctta
    78661 tatggagatg ttaacgacga aagaaagtgc ggtgattttg aataagctca aacaaatcgt
    78721 gatgttgggt cgtcaatctg gtttctttct gattttggct tgccaaaggc cggatgcgaa
    78781 atatttagga gacggaatcc gcgatcaatt caactttcgc gtggctttgg gtcgtatgag
    78841 tgaactcgga tattccatga tgtttgggga ggtcgaaaaa aacttcttta tgaagcacat
    78901 caaaggtcga ggttatgtgg atacaggtgg cagtgtgatt agtgagtttt atacgccact
    78961 tgtaccaaaa gggtatgatt tcttagattc aattagtaaa ttagaaaaga tgaatgattg
    79021 agtgatcttc aatactgact ttatacttca agtaacgtat aatactttta tatagtagga
    79081 agaaagggga taattaatat ggaaagtaat gattcttatt tagagtatgc aaaagcaaat
    79141 aaggataagt ttatttctta tattatcaaa gggaaatccc ccgaagttgg acgagacgca
    79201 gtttttatgg cagggagtcc tggggctgga aaatcagagg ttgccattgg attagctgag
    79261 aattatgata accatgtgat tattgatgcg gattactttc gcacccagtt tcctgattat
    79321 aatggaaaaa actctagtct ctttcaaaaa gcatcttctt ggttggtaga gcaggcattt
    79381 agatatgtct tagatcatgg ctattctttt attctggatg caacttttgc aatattaagt
    79441 gctgaaaaaa atatctcgcg ggcgttgaaa aaacattttc gagtgacgat tttctatgtt
    79501 tatcaagacc ctaaaatcgc ttggaaattt acacaagaac gtgaaattgc agagggacgt
    79561 catgtgccga aaaaggcatt tattaacgct tttttcaaat caagagagaa cattgcaaaa
    79621 gtaaagagta aacatccaga tgtattgctt catatcataa taaaagatta tacgaataat
    79681 atttccgaag ttcattatgc tacggataat ctagaattat ttttaccact agggtatagt
    79741 aggaaagatt tggaggttca attacatgac tgagaaagaa caagtaacga aaattgtaaa
    79801 gaaatacaat aagagcattg cggatttatc ggaaaatgct actgcaaaag agttcaaaac
    79861 ggtgattaaa tatgtagccg atcaggccaa tgaaaaacaa cggaaattag ttggattaaa
    79921 taaaaaatag taggacaaat taataatgta tgagccaaga gcaaaatgtt cttggctttt
    79981 ttctttgcaa tgaatgaggt aatgtatgag atttttagat ttattcgccg gtattggtgg
    80041 ctttcgttta ggtatggaac aggcgagcca tcattgtatc ggtttttgtg aaattgataa
    80101 atttgctaga cgtagttata aagcaattca tgatacaagt aaggaggtgg aaatgcatga
    80161 catcacaagt gtatcagatg agtttattca atccctcgga ccagtggaca tcctttgcgg
    80221 cggatttccg tgccaagctt tttcaattgc gggaaagcgg caaagatttt ccgatactcg
    80281 aggtacttta ttctttgaaa tcgctcggtt caccactctt ctccgaccta agcttttatt
    80341 ccttgagaac gtccgaggat tgctcaatca cgaaggaggg gctacgttcg agacgatcct
    80401 ccgaacgctg gatggattgg ggtatgacgt ggagtggtag gtgcttaact caaaggccta
    80461 cattccccaa agccgggagc ggatattcct tatcggacat tctcgagacg catgtaccga
    80521 acaagtattt cctatcattg gaccgtcttc aacatctgat caaaacatca gaaatttggt
    80581 aaatatcaat ccttccaatc gaggaatggg tggacaagtc tatggttcag atggcgtagc
    80641 gccaacctta acaggtgatg aaggaatcaa aatcgcactg ccagcaaggg atggaatctc
    80701 tgtagcagga ctattaccgg gaaagtttga acaaggtaat cgagtttatg aagttactgg
    80761 aaccgccccc accttgtcaa cgaaacaagg tggtacaaaa atcatgattc gaaaaaatga
    80821 aacagaatat caagaggtga agccagaaga cagtgtgaat ctggcttttc ctaattccac
    80881 aagtcgccga ggtcgtctgg gaaaacagag tgttcatacc ttactaacag gagaccaaca
    80941 agcgatcgtc acggatcagt atcaaattcg gaagctaaca cctagagagt gttggcgact
    81001 tcagggcttt cccgattggg cttttgatcg agattctcaa gtcaattcag atagtcagtt
    81061 gtataagcaa gccggaaact ctgtaacagt tccggtcatt tttgatattg ccagaagatt
    81121 aaaagagttg gatgtacatg gtttatgatg agttgattgg agaaatttat tgggtgattg
    81181 gaaagattca gtcagaccca gaattagaag aacaattgcg acggttaaaa tttgatattc
    81241 gcaagaatgg tgtcaaagtc gctggcgatc catatttaat gaatgaggag acggatgctc
    81301 gaattgaaat aaatcaagta attgcagaat ttgagcggat tgcggaccaa gcaaaagaac
    81361 cagatattcg tcaatacttg ttagaaatga aagcagagtt ggaagtaaat ggtattacag
    81421 atgagtaacc taaaccaaca caactgactg ttaggcgctg accgcggagg attcgcgaag
    81481 cagaaatcct ccgtggtgct gtgcctgttc atggacggcg ttagccgacc atgatgtctc
    81541 acccccgtat ctaacagggg ggtacaaaaa cacaaaaaat aagtaagcaa ccattaagaa
    81601 tgcttgttgt atcaaagata gtaagtaatt tgtataggtg ttaactcatt tgaaaaagtt
    81661 aacaccttga atttggaggt gagaacttgg cacaacggaa tttagattat cggctattaa
    81721 aagaccgacg caacgaatac ggcgtttcac aaaataaatt ggctacggct tgtggactta
    81781 gtcggccgta cttaaatcag atagaaaatg gtggcgtaac cgcatctata aaaaccatga
    81841 ggaaaatttt tgaccaactg gaaagcttta atcccgattt gcctttgacg ttactgtttg
    81901 actatgtaag gattcgcttt cccacaacgg atgcacgaaa aattattcaa gaaattctcc
    81961 atttgaaatt tgagtatatg ctccatgaag attatgcctt ttactcctat caagaacagt
    82021 atgtcatggg tgatattgtg gtgatgttgt ctcatgaaga agataaaggt gt
//
LOCUS       DASHXG010000006        78717 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.006, whole genome shotgun sequence.
ACCESSION   DASHXG010000006 DASHXG010000000
VERSION     DASHXG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.006"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1014..1304)
                     /locus_tag="U2R59_000497"
     CDS             complement(1014..1304)
                     /locus_tag="U2R59_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964919.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="U2R59_000498"
     CDS             1706..1942
                     /locus_tag="U2R59_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964920.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="U2R59_000499"
     CDS             1949..3901
                     /locus_tag="U2R59_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HEM8964921.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="U2R59_000500"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="U2R59_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HEM8964922.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="U2R59_000501"
     CDS             complement(4797..5489)
                     /locus_tag="U2R59_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEM8964923.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            5884..6507
                     /locus_tag="U2R59_000502"
     CDS             5884..6507
                     /locus_tag="U2R59_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8964924.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(6591..7313)
                     /locus_tag="U2R59_000503"
     CDS             complement(6591..7313)
                     /locus_tag="U2R59_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEM8964925.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7303..8040)
                     /locus_tag="U2R59_000504"
     CDS             complement(7303..8040)
                     /locus_tag="U2R59_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964926.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(8052..9044)
                     /locus_tag="U2R59_000505"
     CDS             complement(8052..9044)
                     /locus_tag="U2R59_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8964927.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(9059..9802)
                     /locus_tag="U2R59_000506"
     CDS             complement(9059..9802)
                     /locus_tag="U2R59_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8964928.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(9876..9980)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10043..11365)
                     /locus_tag="U2R59_000507"
     CDS             complement(10043..11365)
                     /locus_tag="U2R59_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8964929.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(11352..12317)
                     /locus_tag="U2R59_000508"
     CDS             complement(11352..12317)
                     /locus_tag="U2R59_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8964930.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(12314..13852)
                     /locus_tag="U2R59_000509"
     CDS             complement(12314..13852)
                     /locus_tag="U2R59_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEM8964931.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(14268..14555)
                     /locus_tag="U2R59_000510"
     CDS             complement(14268..14555)
                     /locus_tag="U2R59_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964932.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            14689..15357
                     /locus_tag="U2R59_000511"
     CDS             14689..15357
                     /locus_tag="U2R59_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8964933.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(15648..16388)
                     /locus_tag="U2R59_000512"
     CDS             complement(15648..16388)
                     /locus_tag="U2R59_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964934.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16518..17465)
                     /locus_tag="U2R59_000513"
     CDS             complement(16518..17465)
                     /locus_tag="U2R59_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8964935.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(17594..18358)
                     /locus_tag="U2R59_000514"
     CDS             complement(17594..18358)
                     /locus_tag="U2R59_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8964936.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(18362..18751)
                     /locus_tag="U2R59_000515"
     CDS             complement(18362..18751)
                     /locus_tag="U2R59_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964937.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            18886..19428
                     /locus_tag="U2R59_000516"
     CDS             18886..19428
                     /locus_tag="U2R59_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HEM8964938.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            19576..20208
                     /locus_tag="U2R59_000517"
     CDS             19576..20208
                     /locus_tag="U2R59_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964939.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(20342..20467)
                     /locus_tag="U2R59_000518"
     CDS             complement(20342..20467)
                     /locus_tag="U2R59_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8964940.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(20601..21494)
                     /locus_tag="U2R59_000519"
     CDS             complement(20601..21494)
                     /locus_tag="U2R59_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEM8964941.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(21676..22602)
                     /locus_tag="U2R59_000520"
     CDS             complement(21676..22602)
                     /locus_tag="U2R59_000520"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEM8964942.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(22687..23448)
                     /gene="pflA"
                     /locus_tag="U2R59_000521"
     CDS             complement(22687..23448)
                     /gene="pflA"
                     /locus_tag="U2R59_000521"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEM8964943.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(23692..25923)
                     /gene="pflB"
                     /locus_tag="U2R59_000522"
     CDS             complement(23692..25923)
                     /gene="pflB"
                     /locus_tag="U2R59_000522"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEM8964944.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(26200..28650)
                     /gene="parC"
                     /locus_tag="U2R59_000523"
     CDS             complement(26200..28650)
                     /gene="parC"
                     /locus_tag="U2R59_000523"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEM8964945.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(28662..30707)
                     /gene="parE"
                     /locus_tag="U2R59_000524"
     CDS             complement(28662..30707)
                     /gene="parE"
                     /locus_tag="U2R59_000524"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEM8964946.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(30873..31307)
                     /locus_tag="U2R59_000525"
     CDS             complement(30873..31307)
                     /locus_tag="U2R59_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEM8964947.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            31434..32072
                     /gene="plsY"
                     /locus_tag="U2R59_000526"
     CDS             31434..32072
                     /gene="plsY"
                     /locus_tag="U2R59_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEM8964948.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(32204..33079)
                     /locus_tag="U2R59_000527"
     CDS             complement(32204..33079)
                     /locus_tag="U2R59_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HEM8964949.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(33161..33952)
                     /gene="codY"
                     /locus_tag="U2R59_000528"
     CDS             complement(33161..33952)
                     /gene="codY"
                     /locus_tag="U2R59_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEM8964950.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(33970..35370)
                     /gene="hslU"
                     /locus_tag="U2R59_000529"
     CDS             complement(33970..35370)
                     /gene="hslU"
                     /locus_tag="U2R59_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HEM8964951.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(35384..35932)
                     /gene="hslV"
                     /locus_tag="U2R59_000530"
     CDS             complement(35384..35932)
                     /gene="hslV"
                     /locus_tag="U2R59_000530"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HEM8964952.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(35969..36874)
                     /gene="xerC"
                     /locus_tag="U2R59_000531"
     CDS             complement(35969..36874)
                     /gene="xerC"
                     /locus_tag="U2R59_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HEM8964953.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(37072..38448)
                     /gene="trmFO"
                     /locus_tag="U2R59_000532"
     CDS             complement(37072..38448)
                     /gene="trmFO"
                     /locus_tag="U2R59_000532"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HEM8964954.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(38417..40495)
                     /gene="topA"
                     /locus_tag="U2R59_000533"
     CDS             complement(38417..40495)
                     /gene="topA"
                     /locus_tag="U2R59_000533"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEM8964955.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(40617..41474)
                     /gene="dprA"
                     /locus_tag="U2R59_000534"
     CDS             complement(40617..41474)
                     /gene="dprA"
                     /locus_tag="U2R59_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEM8964956.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(41530..42297)
                     /locus_tag="U2R59_000535"
     CDS             complement(41530..42297)
                     /locus_tag="U2R59_000535"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEM8964957.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(42290..43150)
                     /gene="ylqF"
                     /locus_tag="U2R59_000536"
     CDS             complement(42290..43150)
                     /gene="ylqF"
                     /locus_tag="U2R59_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEM8964958.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            43410..43808
                     /locus_tag="U2R59_000537"
     CDS             43410..43808
                     /locus_tag="U2R59_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8964959.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            44087..44587
                     /locus_tag="U2R59_000538"
     CDS             44087..44587
                     /locus_tag="U2R59_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HEM8964960.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(44670..45221)
                     /gene="lepB"
                     /locus_tag="U2R59_000539"
     CDS             complement(44670..45221)
                     /gene="lepB"
                     /locus_tag="U2R59_000539"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEM8964961.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(45373..45600)
                     /locus_tag="U2R59_000540"
     CDS             complement(45373..45600)
                     /locus_tag="U2R59_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEM8964962.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(45597..46115)
                     /gene="msrA"
                     /locus_tag="U2R59_000541"
     CDS             complement(45597..46115)
                     /gene="msrA"
                     /locus_tag="U2R59_000541"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8964963.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(46135..46848)
                     /locus_tag="U2R59_000542"
     CDS             complement(46135..46848)
                     /locus_tag="U2R59_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEM8964964.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(46851..47747)
                     /locus_tag="U2R59_000543"
     CDS             complement(46851..47747)
                     /locus_tag="U2R59_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8964965.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(47905..48747)
                     /locus_tag="U2R59_000544"
     CDS             complement(47905..48747)
                     /locus_tag="U2R59_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8964966.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            48879..49532
                     /locus_tag="U2R59_000545"
     CDS             48879..49532
                     /locus_tag="U2R59_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEM8964967.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(49595..50122)
                     /locus_tag="U2R59_000546"
     CDS             complement(49595..50122)
                     /locus_tag="U2R59_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8964968.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(50142..51089)
                     /locus_tag="U2R59_000547"
     CDS             complement(50142..51089)
                     /locus_tag="U2R59_000547"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEM8964969.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(51101..52987)
                     /locus_tag="U2R59_000548"
     CDS             complement(51101..52987)
                     /locus_tag="U2R59_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8964970.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(53147..55225)
                     /locus_tag="U2R59_000549"
     CDS             complement(53147..55225)
                     /locus_tag="U2R59_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HEM8964971.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(55238..55513)
                     /locus_tag="U2R59_000550"
     CDS             complement(55238..55513)
                     /locus_tag="U2R59_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964972.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(55875..56330)
                     /locus_tag="U2R59_000551"
     CDS             complement(55875..56330)
                     /locus_tag="U2R59_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964973.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(56484..57692)
                     /locus_tag="U2R59_000552"
     CDS             complement(56484..57692)
                     /locus_tag="U2R59_000552"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEM8964974.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(57804..58136)
                     /locus_tag="U2R59_000553"
     CDS             complement(57804..58136)
                     /locus_tag="U2R59_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEM8964975.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            58284..59159
                     /locus_tag="U2R59_000554"
     CDS             58284..59159
                     /locus_tag="U2R59_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8964976.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(59241..59822)
                     /locus_tag="U2R59_000555"
     CDS             complement(59241..59822)
                     /locus_tag="U2R59_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HEM8964977.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(59828..61087)
                     /locus_tag="U2R59_000556"
     CDS             complement(59828..61087)
                     /locus_tag="U2R59_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEM8964978.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(61089..62135)
                     /locus_tag="U2R59_000557"
     CDS             complement(61089..62135)
                     /locus_tag="U2R59_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964979.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(62370..62645)
                     /locus_tag="U2R59_000558"
     CDS             complement(62370..62645)
                     /locus_tag="U2R59_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEM8964980.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(62888..64198)
                     /gene="der"
                     /locus_tag="U2R59_000559"
     CDS             complement(62888..64198)
                     /gene="der"
                     /locus_tag="U2R59_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEM8964981.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(64380..65609)
                     /gene="rpsA"
                     /locus_tag="U2R59_000560"
     CDS             complement(64380..65609)
                     /gene="rpsA"
                     /locus_tag="U2R59_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEM8964982.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(65744..66424)
                     /locus_tag="U2R59_000561"
     CDS             complement(65744..66424)
                     /locus_tag="U2R59_000561"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEM8964983.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(66473..67108)
                     /locus_tag="U2R59_000562"
     CDS             complement(66473..67108)
                     /locus_tag="U2R59_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8964984.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(67174..68577)
                     /locus_tag="U2R59_000563"
     CDS             complement(67174..68577)
                     /locus_tag="U2R59_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HEM8964985.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(68564..69595)
                     /locus_tag="U2R59_000564"
     CDS             complement(68564..69595)
                     /locus_tag="U2R59_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8964986.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            69626..69847
                     /locus_tag="U2R59_000565"
     CDS             69626..69847
                     /locus_tag="U2R59_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEM8964987.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(70012..70749)
                     /locus_tag="U2R59_000566"
     CDS             complement(70012..70749)
                     /locus_tag="U2R59_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEM8964988.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(70902..72242)
                     /locus_tag="U2R59_000567"
     CDS             complement(70902..72242)
                     /locus_tag="U2R59_000567"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HEM8964989.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(72479..74002)
                     /locus_tag="U2R59_000568"
     CDS             complement(72479..74002)
                     /locus_tag="U2R59_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEM8964990.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(74380..74991)
                     /locus_tag="U2R59_000569"
     CDS             complement(74380..74991)
                     /locus_tag="U2R59_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8964991.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(75114..75239)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(75321..76037)
                     /locus_tag="U2R59_000570"
     CDS             complement(75321..76037)
                     /locus_tag="U2R59_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEM8964992.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(76043..76612)
                     /gene="scpB"
                     /locus_tag="U2R59_000571"
     CDS             complement(76043..76612)
                     /gene="scpB"
                     /locus_tag="U2R59_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HEM8964993.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(76596..77393)
                     /locus_tag="U2R59_000572"
     CDS             complement(76596..77393)
                     /locus_tag="U2R59_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEM8964994.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(77363..77734)
                     /locus_tag="U2R59_000573"
     CDS             complement(77363..77734)
                     /locus_tag="U2R59_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEM8964995.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(77753..78640)
                     /gene="xerD"
                     /locus_tag="U2R59_000574"
     CDS             complement(77753..78640)
                     /gene="xerD"
                     /locus_tag="U2R59_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEM8964996.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT        22047 a        16376 c        13361 g        26933 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacgc ggatttgtca taaattgtca tgcttctttt acctatgaaa tattttcacg
     5821 tgttaaagta ttcctcgttg aacacaacaa ataaaacttt ttaacgaata aaggagattt
     5881 ttcatgacat cacttaaaac tttacttttt ggaacaactt tggctgccgg cgctgcattc
     5941 ttcatgggaa cgactgctca tgcggacgaa gcttataccg ttcaatcagg tgatactcta
     6001 tcaacgattt ctcaaaaata cgttggtgat aactccttga tcaatgccat tgcagaatca
     6061 aattcaattt ctgatattaa cctgatttac tcaggacaac aattaacaat cccaacagaa
     6121 ggctctgcac aagcagctgc tgaacctcaa gcagccgttc aagaagcacc agtccaagct
     6181 gaacaacctg ttgtacaaga aacggttcaa acggaaaaac aagcagcgcc tgttgctgaa
     6241 acacaacctg ctcctgctgt aacagaaact gctgctactc cagcaagcac aagctctgca
     6301 aaagaatgga tcgcacaaaa agaatcaagc ggttcttaca cagcaacgaa cggacgttac
     6361 atcggacgtt accaattaga ttcttcttac ttaaatggtg actactctgc tgcaaaccaa
     6421 gaaagagtag cagaacaata tgttacttca cgttatggtt cttgggaagc ggcgaaagca
     6481 ttctgggaag caaacggttg gtactaagat tcatttatta atcaaacagt ttacttttat
     6541 acaaagaaag ccaaaaagag gtgcgacact agttgtgtca catctctttt ttatttacct
     6601 aatctaatga aacgttccaa gttttgataa gtattttttt taacttcttc aactgatagc
     6661 tctttgatct cagcgattgt ctttaactgt tcttcaagca gtgagacata atctttttct
     6721 gaaaaaatcc cccctaaagc ccactctgct gcatgtagtc catccgtttc aataagtaag
     6781 tggtcgattg ggactgcttt agctagttgc cagactgctg gattcttttt caaatcaaga
     6841 ccaatgctga aataacagcc taaatcaata tagtcttgtt gatagtccaa agaagaatac
     6901 caatggatca aatagtgatt agggtaagct tggatataat ttaagatctc tttttcgcat
     6961 ccttttgtgt gcagtacaac aggtttctca tttatggctg caaaagcaag ctgtcgctca
     7021 aatacttttt tttgtgtagt catcggtaca ttcgtccaaa tattatctaa ccctatttca
     7081 ccgatgatcc ttgctttttt caaaaaaggc tcaacttgtt caaacgtata gctatctgct
     7141 ttccaaggat ggataccgta acttaaggct tgagtcttac ttgctgcaag ctgtctgttt
     7201 tccttccatt cttctggcga atcacaattg atgatcgtca aaatcgtgtg ttcctgctga
     7261 aggagtgcta aactctgact cccatctaaa tgacaatgag catcacttaa catctaattc
     7321 acctgccaat aactgataaa tcgtttgctt caactctgat tgctgcagta gccattcacg
     7381 tgaccgtcgt ttttcaggca cttgaatctc agcaatcaca tgtgccggac gggcggaaag
     7441 cacaagaatc ctgtctgata aataaattgc ttcttcgata tcatgcgtca caagtaaagt
     7501 agtccgcttt gcttttttag gcagcttcaa catccagtct tgcatctgcc ctctggtcat
     7561 agcatctaac gctccaaatg gttcatcaag aagcaagtaa gaagaaggat tcatgattgt
     7621 tcgtaacaag gccgttcgct gcttcatccc gccagataat tgttccggca aaaaatgttc
     7681 atagccgttt aacccaaaga tatccagata atcccttact tgttcttcat tgattgttag
     7741 atgattgatt ttttgatata acgtaacgtt ttgatagacg ctcagccaag gaagtaacat
     7801 atcttcttgc ggcatataac taaatgctgt atggagacca gttacttttt gatcgtctac
     7861 tttgatcgtt ccagaagtca taggctggac tcctgttaaa gttttcagca atgttgactt
     7921 accggctccg cttggcgcga caatcgatgt aaaggtatct ttagggatag tgaaatggat
     7981 gtcttctaat attttcaggt tttcaatgac tacattcaag tggctgattt ggattgacat
     8041 atctatcact cctattttat aaactgatta gtgaatagtt cttgcgaagg tacatcttgc
     8101 ttgatcaatc cgttttcctg cataaaagct gtataattgc gccaaacttt ttcttccatc
     8161 aatccccaat tctcaggatc atccgtataa ttttttgaca agaatgcttg tgattcttct
     8221 aaaaacgtcc gatcattttc ttttgcatat ttttgcaaca gtttagcact gtcatttgga
     8281 tccttaatag cttcctgata gccttttttc gtggcatcca taaaagactg taccaattct
     8341 ggatcacttt tgatcagttg atcattcgta ataattaccg gagtatagta atctaaccgt
     8401 tcatctaatt ctttcaatgg gatatagttt agttcaatac ccgcttcttt tgctttgatc
     8461 atatcccaac cttcaaagta ccattggata tctgaggatt ttcctaagct ttctggccct
     8521 tctccattgc ttcctaccat tgtcagtttt gaaaagtccc cgccgtcttt ttccatcaca
     8581 gcttttaaga cagcttcttc acttggactt tgccaacctg catatgtttt tccttcaaaa
     8641 tcttttggtg aatggatgtt actgtctgat agggtggcga atccagaagt attatgtttg
     8701 atcactgtag caattgcttt gactggtata ttctgtccat ctgcgtgagc ataagtgaca
     8761 tcttcttgat aacttacacc aaattgtgct ttgtccgcac ctactagacc aatacttgtc
     8821 gaattatctc ctggttcgat gatttggaca tttaaaccag cctctttata atagcctttt
     8881 tcttttgcta ggtagatgcc agtatgatta gtattcggta cataatccaa aacaagtgtc
     8941 acttttttca aatcctttat ttcttgtttg ctacttgttt cttttgcagt gccacaagcg
     9001 gataaaagca acagtagcgg taataaaagc cataattttt tcatttgatc cccttctctt
     9061 aaaaaatata aagcatacga taataccctt ttttcaataa tgaacaagcg ccattcagca
     9121 ataaactcaa tagaatgaca caaatgatcg cagcaaaaac tttatcgatc tggtagctgt
     9181 tttttacgcg tatcatgtaa taccctaagc ctgcttgagc gcttagccat tctccaacga
     9241 ctgctccgct gacacaataa gtagcagcca cttttaaacc ggaaaagaag ccggataaac
     9301 ccgctggtat tttatatatt cgataaatct tccctgtatc tgcccccatc gttttcaaaa
     9361 agatgatttg ctcttttgat actttcctca atgtatccga aaaagaaact acgatcggaa
     9421 aatagcttat caagacaaca aggatcactt ttggaagcat accgaaacca aaccataggg
     9481 taagtaatgg ccctaacacc atgattggca acatttgtga aatcactagt aacggataaa
     9541 aagacatttc taaaaacttc caataatcca ttgccaaggc agtaataaaa gaaagaacgc
     9601 tagctattac caaaccaagc actgcttcat ttaatgtcgt gacagaatgg gaaagtaata
     9661 cttgtgcatc tgccgctaat gcagaaaata cagcagcagg tccgggtaaa ataaaggcag
     9721 gtattttcca aactatgaca acaatctgcc aaataattaa aatgaatgcc atactgactg
     9781 ctggataaag atttttcttc attttgttac ctcctttctt ctaatatgaa taacaaaaaa
     9841 cgcttgaaat gggcacgaca tagtaacccg cttcaagcgt ctgctatgtt tctcccttca
     9901 ccagtattaa ctgacaggtt caatgggtct aagttcacaa cttactctca tgtcgtctac
     9961 gacatcccca gaaacaggta ttcatttttt aaagtgtagc acaagaagga aaaagcaaca
    10021 agcgctttag ttatcatgct gattatttca ataaatagga gagatcactt gccaatgtcg
    10081 gataccccat gatatagcta tccaactctt ttttagtcaa tttttgattg atgacgagtg
    10141 tcaaatcatc gatcaattcg tctgcttgct cgctaatcac tgcagcacca atcaaataat
    10201 tttgctggtc aaaggtcaat tcagccttag caactggttc attgacacga tgataggtga
    10261 accaactggt aagatccatc tctaccactt gatctgacga agaggcgtga ctttttgtaa
    10321 ctcctacttc agcaagttta ggactggcgt agacgatcgt aggtataatc ggatatttga
    10381 taggttcgct tgttgcatcc gttatccgct tagctacata atttccttca aaagtggcga
    10441 ctggtgtcaa ttttggggtt ttccttgaaa caatatctcc acacgcaaaa atttttggat
    10501 tgctcgtttg cagataatca ttgactgcaa ttccgtgttt atcaaagacg atattcgctt
    10561 gctcaagtgc taaagattct gtattcggct gtctcccagt cgcacaaaaa atcatatctg
    10621 ctactaattc cgtctctttt ccgactaaac gatagcgagt accttctgaa atgatctttt
    10681 gggtttcaac accaaaagca aactgaatgc cagatgcttc catttgatgg acggcttcct
    10741 ctaccaaaga cgcctcaaat tcttttaatg gccgttgatt atgatggaca atggttactt
    10801 tgctccctgc agcattggca atcgtagcta gctcaaaagc aatataacca ccaccgataa
    10861 aaatgatttc tttaggcagt acaggcaatg ataaaaagtc tgcactagtt ttcaagtatt
    10921 cctttccctc cactggtaag atcgtaggtc tttgcccggt tgccaaaact aagtaatccg
    10981 catggaagac ttcttcgttg acttcaatag atgaatcatc caaaaaacga gcggttcctg
    11041 aaagatgatc gatttcagct tctgctaatt gtttttttcg gctttctggg actggatccg
    11101 taaatgttcg tttgaatttt tgaagttctt cccagttggc agttgggatc tcgttaaaac
    11161 cttttccact caattgtttt acccgattac gtgcctctac tgcacttaac aagacttttt
    11221 taggatcaca tccacggtta ggacaagtcc cgccccatag atcttcttcg accactagta
    11281 ctgttttacc tgcttctttc aatccataag cagcacttaa gccgctcaca cctgaaccga
    11341 tgatgattgc atcatatgtt ttcatttcct tcctcctctc gacttaaaaa agcaaagatt
    11401 tctttacttg tcagcgaccc aatacttctt tgcttttcta ctatcacaat gcttggatac
    11461 accgaaagaa gcgaatatac ttctttcata ggcgtatcaa agcaaacttg ttgacgagca
    11521 ttttctggta tttcatttaa gaaatatcca ttgacgacta aatcttctac tcgccactct
    11581 ttcgtctgtt tcggttcatc aaagaaatgc cgaacgtagt cgtttttagg attcatcaat
    11641 aactgctctg gtgtgtcaca ttggataatt tctccatcct tcataaatgc aatacgatca
    11701 cctagcttga ttgcttcttc catattgtgc gtaacgaaaa cgatggtcgt gcccaattct
    11761 tcgtgtaagg acaaaaccaa ttcttgtaat gagtttcttg aaatcggatc taatgcgcta
    11821 aatggctcgt ccatcaaaat cacatctggg cttgcagcaa tagctcggat gatcccgatc
    11881 cgttgctgtt ctcctccaga caactctcta ggcatacgat ctcgataaat atcaggagat
    11941 aagccaactt tttgaagaag ttcatctaca cggtctgctc ttttctgctt ttcccaacct
    12001 aacatttcag ggatgacttc aatattttgc ttgactgtca tggtcgggaa caaagcgatt
    12061 tgctgcagca catatcccat attccaccgc attttctgca gattatattc atttaacgat
    12121 tttcctttga agtagatgtc tcctgctgat ggtttagata atccattgat cattttcaaa
    12181 gtagttgttt ttccactacc ggaaggacca accaaaacaa agatttctcc ttttttgatt
    12241 gccagattta ggtcatcgat gacatacttt ccatcatact ttttttgcac atgtttgaac
    12301 tcgattaatt tagtcactga tcttcctcct ttactaatcc ttcatttttc aggaagattc
    12361 gtgctacttc tgtcggcttt ttcttttcga cattgacttg gtaattcata tcaatcattt
    12421 gatcctctgt tatttttccg cttaatttat tcagtgcttt aacgatttca ggatgttctt
    12481 tagcaaaatc ttttttcatc agcggtgcgc cttgataagc tgggaataac cctcgatcat
    12541 cttctagagt cactagatcg tactccttga gctggctatc tgtggaatag gcatccacaa
    12601 tattgacatc tccattattg attgcttggt aacgcaaact tggctccatg ctttgtacac
    12661 ttgaaaaatt caagccatat gcttcttgga ttcctttata tccatctgaa cgatcaataa
    12721 attccagtgt gaatcccgct ttgatctgat cagagatagc tgccaaatcg gaaatctttt
    12781 taagttgatg ttcgttcgca aaagatctct tgactgccaa ggcatacgta ttttggtaag
    12841 ccattggttt taataatgtc atatcgaatt gcttattcaa taattcttct gcttcgtcat
    12901 atgttttttc ttttgtcaaa tcagcacttt tcattgcttc aggtaccttc accaagcttt
    12961 ctaggacagt acctgtgaac tcaggataga tatcgatttg accttgatcc agtgcattga
    13021 acaaaaaact cgtcttgcca aaattcggtt ttaattcaac ttctgttttt gtgttgtctt
    13081 caatcaattc tttatacatt tggatcagga tttcaggttc cgctcctaat tttccagcaa
    13141 tcgtgatggt ttcattttta aacaaggcag actgatataa agaaacgccg ccaaataaac
    13201 acaccactgc tgctaaagta atgatggaat atcgaggttt cttatgctgc aaccagcgaa
    13261 tcagtccgct gaatataatt gcaagcaagg cagaactgat cgcaccaatc aatgtcaaaa
    13321 caggtgtatt tcggtcaata cctaacaaaa taaatgtccc taatccacct gctccgatca
    13381 atgctgccaa agtagccgta ccgatgatta aaactaaggc agttcggata cctgagataa
    13441 tgacaggtaa tgcgatggga agctctactt tcagcaagcg tctcattctg gacataccaa
    13501 atgctaccgc tgcttcttca atagacgggt caatttcagc tagaccaata tacgtgtttt
    13561 ggaaaatcgg aagcaaagcg taaataacaa gtgcaatcaa tgctggaaca gttccgatcc
    13621 ctacaaatgg gataagtaaa cctaataagg caagtgaagg aatcgtttgg agcacacccg
    13681 tgatctgcaa taagacttct gccatttttt tatgattggc tgcccaaatc gctaaaggaa
    13741 tagcaatcag tgctgcaatc agcaaagaaa tgagagaaat ggacagatgt tgaaatgcag
    13801 cttccagcaa ctcgcctttt ctttcactta atgtttgtat aaaattattc atgcgacctt
    13861 cctttctgtt attctttaag tataaacatt tctttccttt ttcccaacta acttgtcttg
    13921 ccttaacctt acagcacgaa caaaaaaaag aaaaaaatac ctctaaatat gctgacaaaa
    13981 aaagaatcca agcaacaaag tcggatcaac tttttggttc tcgttttttc actacgaata
    14041 ccataaaaat ctatacgaaa ttgtcacttg gaatcagcta tatctttttt acacacacaa
    14101 cttttatttt aataaaaaga aacagccaat aaagtagaaa tctcgtgggg gagaacacct
    14161 ttattggcct gttcaacgaa tattatactg tatcatgaca cttttttgcc aaaaatgtaa
    14221 aaaatggttg ttttgacatc ataaacgtct tgttttctta tttttactta tatcaccact
    14281 ttattttcta tctctttcac tccataaaga ggaatgagtt cttcttttga ctgataataa
    14341 acagctttct cacggttctt catcaaaaaa agaaagatgt ctttcatagc aagtggtgct
    14401 ttgccgtgtt caaataaaaa gataaattga tttgctttat ttatctggac cattgtcaca
    14461 ggcaccagtt tttgttcttg agccaaaaaa actccttgat actctgtttt tttgggtgat
    14521 tttgtaagaa ttgtcaataa gtctgctgct cgcatttttc cactccttat ttgataaata
    14581 aaaagaaaca gccaaaaata attttttttc attttcctct tgaagtaaga gtataagtca
    14641 gtataataaa gaagttgctg aaaattttca aaagaaaaga ggctagaaat gaaaaaatta
    14701 aatttattta cagaattgtg cggaatcatt ttaggcgcag gaatctacgg attagctgtg
    14761 acaggaatca atattccatc taagctggca gatggtgggg ttactggtat tgctttgctt
    14821 ttgcataatc tttttggatt cgctccttct gtcacttcac tgctttttaa tttaccttta
    14881 ttgcttatct cattgtttct ttttggaaaa cacgcttttc tccggacgat cgtcggaaca
    14941 tttgcgctag ttttcttttt acatttatgg gagagccttc atatacattt tgctgtagat
    15001 agtctactga tcaatagttt gatgacaggt attctttctg gcattggttg cggtctcgtc
    15061 tttcgattcg gcggaagcac aggcggaaca gatatcattt atcaagccat tgaaaaatat
    15121 tttcatatta agattggcaa aagtcttttc ttgattactt ttggtatttt agttgtctcc
    15181 ttgctttatt tggatctcac acattttctg tatacattac ttagctgttc tattctatct
    15241 tatacattga ataaagtgaa gtatctggaa attggatctg ttttgcccca attggaagca
    15301 aaacagacta cagaaacatt tgaaccactt gatcctcttg aacagttaga gcactgattc
    15361 ttatttttca ctactttatt taatttacag aaatatcatt atgtaaacta aaatgatatt
    15421 attcagtaaa atcttcttta taaaaaaata aactattttt gcaaacgatc tgcgaaaata
    15481 gtttgttttt ttattttgcc attattttct tacttattgg gagaaaaaat tcgcttaaac
    15541 tcaaaaaaat ttgaggatac gatataaact ttcggataga gtataaaata aggaaacgcc
    15601 gcagcgtttc ctttccaact gtagccgaat ataaatttgt atatcactta tttaaaatag
    15661 ctattttctc ccaaagagtt tccttgatca tcgatcaatc cttgtaatga gcgttctaag
    15721 ataccatggc tttttttcga ttttttttct tctgactgct ttgtttcctc taacgttttt
    15781 gttcgattga atgttcgtac agacggctca ccatttcttt tttcttgata cggcgtcggt
    15841 tctgtatcga acaacagata agagtcatcc gtttttttca tcgattcgat taaatgatcc
    15901 tcagaaattt tgctttctct agggtctggg ataatcgatg cgggtacata tttaggaaca
    15961 aaataagaac gctcccgcac cttcgtgtca acagatgcgt ttcgtgtagt atgcttggac
    16021 tctgtccttg tttcactttg tctgacagaa cgagaggaat caccaaaaag tttttttcgt
    16081 cctgtcgatg tgatttctga ttggtaatgg ccggtataat ccggtaattt tcctttatgc
    16141 ttttccaaat tttccttacg cggagctgac ttcaatccat ttgttgcacg acgcttgcga
    16201 cggattttct cggtgttcgt gttcgtgaaa tgaaattctt tcatctgttc aaacggggac
    16261 tgattctgtt cagtcaaaag atcttcttgt ccgtcaaata atactcgctt cttgtcgttg
    16321 gttaatttta cgcctaactc atcatcgtac gcaggaaaac ggaaatgttt tcgtctgatt
    16381 tctttcattc aaaccatcct tctcaaaaat ggaacttttc tcaataatag cacagattca
    16441 ttgttttcag tagcaatgcg ctgattattt taagaaaata gcgatgaatt tcataaatat
    16501 atatatagta ataagactta attcgttgtc tctctgataa ctagttcagg aaaaaaacga
    16561 cgataacctt gactcgcccc tttttcttct atttttttta acaacatttc tccacatact
    16621 tcacccatac gtataatatc ttgcttgatc gttgtcaatt taggtgaact gatttggtct
    16681 aaaaataccc catcaaatcc aatcacacca aattcttcgg gcaagtgtcc tccagcattt
    16741 ataatccctc ttactgctcc tagtgctagc cgatctgaac tacatacaaa acaagtttta
    16801 tctgtaaaat ctgcccagtt ttctgtcata tatctttcta cttctgtcga atgatttgga
    16861 aaccgcaaga ttttactagg aagatcaact tccttcatca cagataaata accagtttcc
    16921 cttgaaattt caaaaggctc gtccacttcg ataccgatat aaataatcgt ttgataatct
    16981 ctttctaagg catattgcgt tgcttttgct gtaccatatt cattatcgct gtctacataa
    17041 tcatatcctt cagaattttc cccaaacaag acaactggtt tttccaaacg gtcgatccaa
    17101 tcgaagtctt tttttctgac acctgtgatg atgtatccat cacaagaacc gacgtcgaag
    17161 gcatcatttg taactaattg gagagaataa tgcgctttac cgatccgttt agcgattccc
    17221 atcagcaaat tcatgtaata gggctcagtt gtgtcgattt cttccagtat aaataatttg
    17281 atgatctgcg accgattcgt gacaagtgct tttgcagcaa tatttggacg gtaatccagt
    17341 tcagccattg ctgagaaaac taactctttc aattcgtcag tcacctgttc cggatgattg
    17401 atgactcgag agaccgtcat ttttgaaaca ttggcacgtt ttgcaacatc tgctaaagtg
    17461 ggcatgctct cttcctttct aacatgttgt cattcttact atcaattata ccaaattttc
    17521 ctaacagagt ttattatagc ccaaaataaa aaacggaaaa tcctctatcg tcatgagtga
    17581 ttttccgttt caattattta tactttttta tcaaattttt tgctaaaaaa gtggaagctt
    17641 cttccattag tggtatttgt accatatgtc gctgtgtttt tgaggaacga aaaacaattt
    17701 cttttccgta agacttatgc cgattttttt ctacaaatcg ttccgtttgt atataaggga
    17761 ttttttcgtc agcttgtcca tgccaaaaga acagaggacg tccagctaac ttttccggct
    17821 gcaatgacaa atcatagctc ttaacccatg aaatcaaatc aaaatagtct tttggtacga
    17881 cataattata ttccgatgcg cgccttacga tttcttttcc atattccaaa ggtgcagggg
    17941 aacccatcaa acacacgccc gctactatat gaggatgttt agccaacaag gcgcatgttg
    18001 tcattccccc catcgaaacc ccgccaactg caagctgatc atgtagaaga cctctttttt
    18061 ctaaatgctt gataagtgtg tcaaattcaa acagatttcc gtagatacta tcccaaaatg
    18121 tataggatgg aatagaagaa accggctgtt tgcgctcccc atgattcatc gcatctggca
    18181 ggatcacacg aatgccctgc tgcgcaattt ttcttccttg cgtcaaaact aactccttac
    18241 ttgtctgcca tccgtgataa tagatgacaa cgggaatacg ttcctctctt aattctttca
    18301 gaacaacttc taacactgga atatgatgga cagaacgttt caatataatt ggattcaatt
    18361 gttactcacc tattttcatt aaatttcctg atcgccatag caaccatgct ccaacagttg
    18421 tctggaacag gttcagtgta ccaaataata taaatgcagg actgaatggc tcgggaaata
    18481 agcacagaga acaaagtccc accactccta atgctagcga aaggagtgga taaatagaaa
    18541 aattcaaaaa actggcaacg ctaccgaaaa tattaccaat aaacagtatc aaaaagaaaa
    18601 aaacgcttaa aattaaacca tctgtcagcg acatctgaaa aacaatgttc tctacctcaa
    18661 ttggctgttg aatcgaatag acacctaagt atatactgag aaggagactt agcacgtggc
    18721 tggcacaaaa cacacgattg accgttttca ttttaatcac ctaacctatc tttataattc
    18781 tattataatc attttatcat ttttttgtat gtataaagtt tcaatttttc ttcacttacg
    18841 attttttttg atattgttgt tatataaatg aaaggagttt tacaaatgat tgatccaaaa
    18901 atgttgggga tgatcttcct cattaatttt gcttatatca ctctgaacac gttacgtttc
    18961 atgttgacaa tgaaaggcta tcgactgatt gctccacttg tcagtatggt cgagatcacg
    19021 atttatatcg tcggcttatc ccttgtttta gatcgtttag ataatccact gaatttattt
    19081 gtctatgcgt taggttacgc agtaggtatc agtgtcggaa ttttgattga agacaaattg
    19141 gcattaggat acatcatggt cacaacgatt ttgccagcaa atagcgcaga agataaaagt
    19201 ttgccgggta tactgagaga acacggttat ggtgtgacac agacttctgc aatggggctg
    19261 gaaggtgagc ggctagttct cgaaatactt tctcctagaa aaagcgaacg tgaactgtat
    19321 cgcctgatca aagaaatcga agagcgtgct tttatcattt cttatgagcc aaaatatatt
    19381 tcaggtggtt tctggactaa aaaagtgaga aaacgacaag gaaaataact cacaaactta
    19441 aaaactgtct aatatctaaa ttaaatttta aatgttagac agtttttatt tattattttg
    19501 attaaaaaac atcgacatat actcatcaat ttgttattat actttatata cttatcaatt
    19561 taatttggag atattatgga aattcaacgt agaaccacta attttttaca tttaggctct
    19621 ttttttgcaa ctttgacgat cttatttttt ctatgttatt cataccttaa gacctcacat
    19681 gcgccttcta gtgcattagg ctggttgctt ttggatcatt ctgatatcac agaagccgaa
    19741 gaaaatccgt tttttttgat tttgtcttct ctttgcggct tactgttttc tgtttatttc
    19801 ggtgcctatt tttttcatcg acatcctggt acgttaaacg aagcttcaag cgtattgatt
    19861 gcatttaaaa cgttttcttt tttagcaatt cttttttatt cgtttaatca caatacgctt
    19921 ttcttcttta tcatgaatgg tttagtcgtg attttatcca tttttactta ttttattttt
    19981 tcactcattt ttagccaatt gaaatgtccg ctcttctttc gattagttcc tgtcacctgt
    20041 tttatttaca gcttgttttc cttttttgtc cttgctttaa tgccactgac caacccttcg
    20101 acgatccaag tcgcaggaaa tctgttggat atgctcttca tcgtcagtct aggtgtattt
    20161 atgtggcaaa gaaaaaacaa acaaaataaa aagcattttg aagcctgact attacgactt
    20221 cataaatgct tttttagttt taaacacttc aatctaaaag aataacccaa gattggataa
    20281 attattaatg actcgccatt cgtttcttag tgattctgga ttatcaaatg gacttcctaa
    20341 tctaatcagc tagttcttcc cataaaatgc catacttgac tgaatcataa tattgattat
    20401 ttaaaaatct aacttttctt atcactactt cctttgtcat tccacatttc tcaccatttt
    20461 tttgcattcc tttgtttcca gaccatgtag tgaatctaat aggtggtaga taggcaaaat
    20521 actcaaataa ttcttttaac cataaaggaa gagaaaggct cctcctgcaa gagtcagtat
    20581 aatttttgct tactgctctc ttaggtttta ctcactaaaa ctgttccata ttctttgata
    20641 taagaaaatg catgcggtat aaatttcttg ctcagctcag aaaagatttg tcgtttaaga
    20701 aaggccattt cctccattgt caatgaagga tccaatgttg gtaattcaat ctcaaaattg
    20761 tttttttcga caataggtaa ttctaatgtg aatgattctt cttcctttat agtattcgtc
    20821 acaagtagag actgatggaa aatactaggc cggcgatttt tatatttatt cttacgtatc
    20881 ctgtcaacga taacttctat ttgatcaaaa aagtacgatt catttacgtc tccaataagt
    20941 tcggctaatt ctttgaatgc cttcgttaca ggaagctgat tcttctgtac aaaaaagtaa
    21001 ttagccaaag taagcgggaa gtgttctata gaggaaagtg tgataaaacg gtacttctca
    21061 tttcctgcag ttgtcctcag caattctgtc tctcggctgt ttcttactcc ataaaaatac
    21121 gcttctttcc gttcatcttc gaaacaatac gcccaaataa cttctcccat cgctaatttt
    21181 tgttcatcaa cagagagtct cttcaattgt tcagctatgg tttcagcagc cgaagtggct
    21241 tgttgcaagt aatctttagg atcaaatatt ggaaagttca aatgatatct tcgttcttcc
    21301 ctcttgatta atcctgcatc gatcaataaa tcaagaaaat gggaaaattt attttgcgaa
    21361 aattcttttt tcaattctct tagaatcgtt tcttgttctc gatgttcata tagataatcg
    21421 gtcaatgaag aaaaaagcgg atcatcggtc agtttttgat aaaagttttc cttatttttt
    21481 gaataatagt tcatatatgt tctcttttct atccgtttta ttttacttaa aaggctttta
    21541 cgtaaaaagg aggaagaaca agagtcataa ttgactgtta ttctcctcca tttcttcggc
    21601 ctttagtatg ttctatgttt ctttttatat caatcgctta tccattcatt ttgaatgctt
    21661 catactacca tttgattagc taaatacagc cgtcaattga ggtacgactt gttttttacg
    21721 tgaaacgaca cctttaagca aagcacggtt gttggtcaaa gttgtttgga aagcttcttc
    21781 tactttttct tttcctttac cagcaacaag taattctgaa tcactgtcta agatgtttgt
    21841 gacaactaat acgaacagat cgtagccatt tgctttcatt tcatcttcca ttgctgcttc
    21901 tagctctgct tgtcgatcca tcacttcatt aaggtccact gtattgactt gagcgatacg
    21961 aacgttggaa ctgcccattg ggaaactttt tgcatccaaa tcaagaagaa ccgcagctga
    22021 tttatcactt agatttgttc ctgctttcaa catttcaagt ccataagtgt ttagatcgac
    22081 ttcagcgatt gctgcaagtt cttttgcagc tgcttcatct tcaggcgtac atgttggtga
    22141 tttgaacaac aatgtatctg aaatgatagc tgagagcatg attcctgcga tttctttagg
    22201 aattgttact tggttttctt tatatagttt taaaataatc gtacttgtac atccaactgg
    22261 ttctgcacga tagtacaatg gattagctgt ttcaaagttt gcaatacgat ggtggtctac
    22321 tacagctaaa atatttactt cgctgatatc tgaaatactt tgttggaatt cattatgatc
    22381 cacaagcatg acatctgcat tttctgcttt agctgactct actactcgtg gtgcagatag
    22441 ctgaaagtgg tctaatgcgt attgtgtttc ttcattaggt gtacctagag caactgcttc
    22501 tgtttcttta cctaattcat tttgcaagtg tgaaaacgca atggctgccc cgattgcatc
    22561 tgtatctgga ttttggtgac caaaaactaa aatttttgac atgtcattcg ctcctttgtg
    22621 atttctccta tttaataata gcaaaaaaac ggaaagaagc aatacttatc ttctttccga
    22681 tgcgacctat cgcgttaaat attttgtata ctcttctgta tgaagcaatc gtttagcatt
    22741 ttcgacacgt tcttttgtag gtggttcgat cccttctaat ggatatttca aaccaagtgt
    22801 ttcccacttg tattttccca tcgtatgata aggaagaatc tctactctgt ctacatttga
    22861 caaggtttga ataaagttgt ctagtcggat caaatattca tcataatcac ttcgctcagg
    22921 aactagtaca tggcgaatcc aaaccggttt gttgattttt gacaaatatt gagccatttc
    22981 taaaatattt tcattgtccc aatgcgttag ttttttatgc tcttcattat cgatgtgttt
    23041 gatgtcaaat aacagtaaat ctgtatactt catcaattct tgaaaacgtg aaaagaaagg
    23101 ttcttcatac gtaaaaggtt ttccgcatgt atccaatgta gtatgcatct tccgctcttt
    23161 tgctttttta aatagttcga tcaaaaaatc gatctgcaat agaggttctc caccactaac
    23221 agtaatacca cctttatctc cccagtaagg tctgaagcgt tctgctttat ctaaaagttc
    23281 atctgctgtg tattctttcc ctccgccaat attccaagta tctggattgt gacaaaattg
    23341 gcaacgcatg cggcatcctt gcataaacac gacaaagcgc agtccaggtc cgtctactga
    23401 accgaaagtt tcgatagaat gaacatagcc gattgttttt tcttccattt aagttcacat
    23461 cttttctttg atttcatttt aagtacaagt tagctgtcga agcgaagctt tctgaacaaa
    23521 atttttcgca attgccgctt cgttatgtgt aaaatttaca gggacggaac atacaagtcc
    23581 tgcccctgta aatcgtttct ttcaaataag catactgatt attcgatttt gatgcgatgg
    23641 ctattcaacg tcctttcgac gctaagtcga aaaacttttt tcacgaactt tttacattct
    23701 gtcgtgtgaa gttctcatca agacatctaa ttgttgttct cttgtcaagt cacggaattt
    23761 aactgcataa ccagataccc ggatcgtcaa gttcggatat ttcattggat tttccattgc
    23821 atcacgcaat aaatcattac tgaatacatt gacattcaaa tgataagctc cttttgagaa
    23881 gtatccatct aagacattac gcaagttttc gattcttgta tcttgttctt ttccaagacc
    23941 tgaaggattg attgtttggg tatttgaaat tccatccaat gcacagccgt aattcatttt
    24001 agctgttgag ttcaggctag ctaataaccc actttgttcc gcattgtaac ttggatttgc
    24061 tcctggcgca agtggttttc cagcttcacg gccatcagga gtatttcctg tatttttacc
    24121 gtaaacaaca tttgaagtaa tcgtcaataa tgaagttgtt ggttttgagt tgcggtaagt
    24181 tttatgacgt ttgatttgtc ccatgaagta ttccaagatc catgaaacta attcatctgc
    24241 acggtcatca tcatttccgt atttagggaa gtcgccatcc acttcaaaat caactgctat
    24301 tcctttttca ttacggattg cttttacttt tgcatatttg atcgctgaca agctgtctgc
    24361 cgcatgagag atcccagcaa tacctgtagc aaatgtgcgt tgcaagtcag aatccatcaa
    24421 agccagctga gctgcttcat aagaatattt atcatgcata taatgaatga tgttcaacgt
    24481 attgacatat agttctgcta accaatccat catattcatg aagttatgtt tcacttcttc
    24541 aaagtctagt atttctgatg tgattggacg atattctggt ccaacttggg cgccagtcac
    24601 ttcatcgact ccgccattga tggcatataa tagtgtttta gccaagttag cacgagcgcc
    24661 aaagaattgc atgtcttttc cgacaactgt tcctgataca cagcaagcaa tcgcacaatc
    24721 atcagaaccc cattgttcac gaagctgatt atcattttcg aattgaatcg aagaactttc
    24781 gatagcgatt ctgctagcat atgttctgaa tccttctgga aggtgttcag aatacaaaac
    24841 agtcaagttt ggttctggtg aaggtcccat atttgttaat gtatgaagca gacggaaatc
    24901 attctttgta actaatgaac gaccatctaa tcccatacct gcaatggata aagtagccca
    24961 gatagggaat cctgagaata attggttata ttcaggtgta cgcgcgaatt tgaccatacg
    25021 taatttcatt actaagtggt cgatcaattc ttgtgcttct ttttctgtga ttactccatt
    25081 atccaaatca cgttggatat agatatcaag gaatgctgag atacgtccga ttgacatcgc
    25141 agcaccattt tgtgatttga ttgctgctaa atatccgaag tatagccatt ggacagcttc
    25201 ttttgcattt gcagctggtt tagaaatatc atagccatat ttcgcagcca tttctttcat
    25261 ttgcgctaat gcacgatatt gttcagtgat ttcttcacgt aaacgaatca cttcttcact
    25321 cattgtatga taaccagtca tatcatgatc ttttttcttt tgttccatca aatagtcgat
    25381 tccatacaat gccacacgac gatagtcacc gatgatacgt ccgcgaccgt aagcgtctgg
    25441 aagccctgta atgattttgt ttttacgagc agcacgcatt tcagcagtat aagcgtcaaa
    25501 tacaccttga ttatgtgttt tgcgccagtc agtgaaaata tgtgtcaatt catcgtttgg
    25561 tgtatagcca ttgcttttta gcgcattgtt agccatattg attccgccga acggcatgaa
    25621 tgcttgtttc aaaggtttgt ctgtctgtag accgacgatt ttttccaaat ctttatccaa
    25681 atagcctgca tcgtgtgaag taatagttga tacgatttct gtgtccatat catagacacc
    25741 gttacgctcg aattggatat catttaactt ttgcaattca tcccataatt tttctgttgc
    25801 ttctgttggg ccttccaaaa agctgtcatc accgcgatat tcagtgtagt tattttgaat
    25861 aaagtctcta gtgtctacgc cttctttcca tttggtacct ttaaatccat tccattgctc
    25921 cattgtatgg acctcctaaa tttctgtttt atgtaacagt ttttacgtga ttagtataac
    25981 acagcaccct atctttgcaa gggttttctt gttttttatt taacaatttt tatgttttat
    26041 ttacatatat ttaaatcaac gttgacatac caacatttaa gcattgtgaa cactttcatc
    26101 tttttttgca aacgtataag gatttattaa aaatgaatga aaaagagacg ccacctgtat
    26161 taatacagat ggcgtctctt cattaaaata ctacaacagt tacgactcga tgaaaatctc
    26221 aggagcatcg ataacttcga tgacttctcc accttttttc tcatccatcg caaatgatcc
    26281 attcgatgtt cgatcaccta tagggaaatc agttgggtca atcgttaact gctgcccttt
    26341 ttgattcatc aaggttattt cttttgatct tccttccgac atatagataa tacggtgcgg
    26401 attttttttc agctcacgca tgaccgtcac tccccgcttc gcacgtgaag tttggctgat
    26461 ttcttgagca agcatgcgtt taacagctcc tcgctgagta acgattacga tcggcgtatc
    26521 accttctgct aacacaagca gcccgttgat aatcctatct ccatctttca aattcataga
    26581 cttcactcca gctgcctttg ctccaacaac gggaacatct gttaaaggat agcgcaaacc
    26641 cattccttga tgcgttacta agaaaacatc taagcctggc tgatcttctt tcagatacac
    26701 agcaatcagt tcatcttctt ccgcctttag cttcatacag ctgagcggac ggctcttata
    26761 ggtgcgccat ggttcgaact ctgtcattcg tgtttgcttg atcaatccat tcttgctgat
    26821 gaatacaaat gttttctctg cttgaatttt ttgatatggg aaaacagcta aaatcgattc
    26881 gtctacagac agattggaga ttgtttgaga aatgtgctca ccagcatctt tccatttcaa
    26941 atcgggtagt tcatggacag ggcggtagat cacatttgct ttatttgtga tcagaagaac
    27001 atggtccaat gtactcaatt cacctgagta tagcaagtag tcgccttctc gcatcccgat
    27061 ttcttctggt ttggaagcac tataagaacg aaggcttgtt cgcttcacat agccttctcg
    27121 cgtcacactg acaattacgt cttcttgtgc cactaagact tgcgtatcaa ttttgatttc
    27181 ttcgatttcg tcttcgattg tcgttagacg agcggaagaa taattttttt tcacttctcg
    27241 caattctttt ttcataacag agaaaagctc tttgtcattt gaaaggattt tattcaactc
    27301 tgtgatttgc gcaatcaagc tttcggattc cttttgaagc tctgtgatat ccgtgttcgt
    27361 caaacggtat aattgcaatg tgacaattgc ttctgcttgt tcttctgtaa attgaaagac
    27421 gtcgactaaa ttctttttgg cgtctttttt gtctttactt tcacgaatcg ttgcgattac
    27481 ttcatccaga atcgataaag ctttcatcaa tccttctacg atatgctgtc ttttttgagc
    27541 tttggctaaa tcgaattgac tacgttttgt tatgacttgc tttcgatgct cgatataact
    27601 tcttaaaatg tctttcagtc caacttgatg cggagtcata tggtcgatag cgaccatatt
    27661 gaaattgtaa ttgatctgta gctcagtgtt tttgaacaaa taattcaaaa ttccttgagc
    27721 attggcgtct tttttcaatt cgacgacaat ttgcagacct gttctatcac tttcatctcg
    27781 tacttcagct attccatcga ttttcttatt caaacggatc tcatccattt ttttcaccaa
    27841 ggtcgcttta tttacttcat atgggatttc tgtgatcacg atttgctgtt tattaccctt
    27901 cattgcctct atctttgttt tcgaacgaag aataactttt cctcgtcctg tttcataagc
    27961 ttttttgatt tcatcttttc cttgcaagat ccctcctgtt ggaaagtcag gtccaggaat
    28021 atattccatc aatttttcaa ggctcgcttg tggatgatcg atcatataga ttgtgccatc
    28081 gatcacttca gctaagttat gagtcgggat ttctgttgca tatccagcag atatacctgt
    28141 cgatccattg acgagaaggt ttgggtatcg agctggaagg actgttggtt ctttttctgt
    28201 atcatcaaaa ttccacacga gatcgactgt ttctttctcg atatctgcta gcatctctcc
    28261 acttaacttg gataatctgg cttcagtata acgcatcgca gcaggtggat caccgtccat
    28321 actcccgtta ttcccgtgca tttcgatcag tacttcccgc aacttccagt cttggctcat
    28381 gcggaccatc gcttcataaa tactgatgtc accatgagga tgataattcc ccatgatatt
    28441 tccgacagat tttgctgatt tacggaatcc tttgtcatac gtattgccat ctttgttcat
    28501 ggcaaataat atccggcgtt gcactggctt caatccatca cggatatcag gcagtgcacg
    28561 ttcttggata atatatttgg aataacgtcc gaagcggtca cccatcactt cttctaaagt
    28621 taattcttgt acttcttgtc gattttccat caggtgacct cctattctac ttcaaataac
    28681 tgattgtttt catttttatc tgctcgttct tcatctaata aatcattaga aactgaagga
    28741 gagatttcag tatcctcttt tttatctaag atactgccat cttcttcgag cgtaaattgc
    28801 acgtgatttt cgatccattt tcttcgaggt tctactttgt cacccatcag tgtggttact
    28861 cgacgttcag cttgcgcagc atcatcgata cggacgcgga tcaacgtacg ggaagtcgga
    28921 tccatcgttg tttcccacaa ttgttccgca ttcatctctc caagtccttt atatcgctgc
    28981 agcatatatc ctttgccgac ttttttaatc attgctgcca attcgtcatc tgtccacgca
    29041 tattcaatga cttgcttctt tccttgtcct ttggatactt tatataaagg cggtaacgcg
    29101 atatatactt tcccagcttc aatcagcggt ttcatataac gataaaagaa agtaagcagt
    29161 aatacttgaa tatgggcgcc gtctgtatcc gcatcggtca tgatgattac tttgtcgtaa
    29221 ttacagtctt cgatagaaaa ctcaggaccg actcctgcac caatcgtata gatcatcgta
    29281 ttgatttctt catttttcaa gatatcttgc attttagctt tttcggtatt gatgactttt
    29341 cctcgtaaag gtagaattgc ttggaacttt ctgtctcttc cttgtttagc agatccgcca
    29401 gcagaatccc cttcgactaa atacaattca tttttcttag ggtttcggga ttgtgcgggt
    29461 gtcaattttc ctgaaagaag agattcgcct tttttacgct tcttcccatt tcggctttct
    29521 tctctggctt tacgtgctgc ttctctcgct tctctggctt tgattgcttt acggaccaac
    29581 atctggctca tttcgctatt ttcctgcaaa taaaagccca tttgttcact gatgacgtta
    29641 tctactacgg tacgagcaac tggcgtacca agtttttctt ttgtttgccc ttcaaattgc
    29701 agaagatttt caggtacacg gatagaaagt acagcagcta acccttctct gaaatcacta
    29761 ccttccagat tcttgtcccg ttctttcagc aaaccaactt ttctcgcata ttcattataa
    29821 gatttcgtca tcgccgcttt cataccagct tcatgggttc ccccatcttt tgtccgaacg
    29881 ttattgacaa aagataaaac attttctgaa taaccgtcat tgtattgata agcgacctct
    29941 acttcgatac cttctttttc tcctgaaaaa taaacaactg gtgtcaatgt atctttttct
    30001 tcattcagat aatcaacaaa ttctttgatt ccttcttcgt aatgaaaaat ttccttgact
    30061 ggttcttctc cacgaagatc agaaagagag attttaacgc cttttagaag aaaggcagat
    30121 tctcttaacc gttcggctaa aatttcatat gaaaatttcg ttgtactgaa tattgtatca
    30181 tctggtaaaa aatggacagt cgtcccgttt gctttttttg tttttcctat ctttttcaaa
    30241 gtaccgtcag gtttaccgcc gtttttaaat ttctgctgat actctacgcc atctctaacg
    30301 atcgttacaa ttagccattt cgataaggca tttaccacac tggctcctac accgtgcagt
    30361 ccaccagaag ttttgtaccc tccttgacca aactttccgc cagcatgcag cacagtaaaa
    30421 atcacttcaa ctgttggtat tccggaagca tgcattccta caggcatccc acgtccgcta
    30481 tctgcaacag ttatactatt gtcttcatgg atggtcacat caatctcact gccataacct
    30541 gataatgctt cgtcaactgc attatcgacg atttcataga ctaaatgatg caagcctcgg
    30601 ctgtcagtgg atccaatgta catccctggt ctttttctaa ctgcctctaa tccttccaat
    30661 acttggatgg acgagtcatt gtattcgttg tttacttttt ttgccaaggc aaacgctcct
    30721 tcaataatac tttgcggcaa aaccgcacca cgattatcat actagaaaag gtcgtgaaaa
    30781 aaaagagggt agacgagaaa tcaattttaa ttatctccta accgcttttt cgacattccc
    30841 ctctatcgat catctcttct ttgtggtcat ttttattttt ggttttcttt caacttacca
    30901 agttcaatct taatacaacg atccattacg atatctgtac gtcctgcttt tcttagcatc
    30961 tcagctgctt ctttgttttc aatccctaat tgtgcccaga acactttagc atcagttttc
    31021 aaaaaatcac ctgctatttc aggtaaaaat tcactccgtc taaatacatc tacgatatcg
    31081 attggatcat cgatttctgt caaattcgca tagactttct cgcctagaat ttcttcacca
    31141 gccaataatg gatttactgg tatgatttta tatccattgt cttgcaatac ctgtgcaacc
    31201 atgtaacttg ttcgttctgg tttattgctc aagcctacga cggcaatatt ttttgcttct
    31261 tccaaatagt tgaaaatcgt ttcttgtgtt ggatttttta cagacatttc tgccacccct
    31321 tgcttttctt tttattccat ctattatact tgtatctttc attttttcaa ttgttcctgt
    31381 tacctattca tgctaaaata aaggatagtt ttcaacttga aagagggtaa aaaatgaaat
    31441 tgatcttatt acttatttta gcatatcttt taggttctat tccttccggt gtctggattg
    31501 gcaaattgtt tttcaaaaaa gatatccgac aacacgggag cggtaatact ggaacgacca
    31561 atacatttcg tgtattaggc aaaacagccg ggattgttgt cctgcttatg gatattttaa
    31621 aaggtacatt ggctacttgt ttgccgatga tcttccacct ttctgggatt aaccctcttt
    31681 ggtttggggt atgcgccatt cttggccata catttccgat ttttgctggg ttcaaaggag
    31741 gaaaagctgt tgcgacaagt gcaggaatgc ttttaggatt taatcctgta ttttttgttt
    31801 attcttgtat catctttatc gttagtttat tttgtacaag tatggtgagt ttgagcagta
    31861 tgatcagtgc agtattgatc actttatcta cgatcgtcct tccttatgta gctcctgtga
    31921 ttttggctaa gcccaattgg ttactgacga tcattgcctt tttagtttct tcctttatct
    31981 tttatcggca taaagacaat atcaagcgta tcagaaacca tactgaaagt cgaatcccgt
    32041 ttggtttgaa tagcagcaag aaaaaatcct gatacttttt cattccaaag agataaaacg
    32101 ggagtgtgac aaatcgatgt cacactccct tattacttac aggatagctt ttttacacac
    32161 cttggtaaac ggtgttccct gctaacttct cggtcacaac ctcttacttc actgtgatgg
    32221 aatattttgt cttgaagatt tcatgggcac ctagttgatt gatccctact ttttccatca
    32281 agtttccact actgttcacc gtgtcagcga ttccgcacca cggttcgata caaacgaaag
    32341 gcgcttcttt tggataagga gaccagatcc ctacataagg catatcttta tagcttaaag
    32401 ttacgctatg ggaagatttt tcacttcgaa tggcgtacgc atttagaccc cttgtttcaa
    32461 aaaccaaggc atcttgctca aaaagttcac gattcaaagc cagattcgta tttgtctgac
    32521 ctaacgtctt ttgatccata tcgatgaatg ggcctttcaa tggtaggcgt aatcttgatt
    32581 tcaatggaga aaatgccaga tagaaatctt caaatgacaa tccttcttca agaggtacat
    32641 tgaaagcagg atgtccaccg atagaaaaga acatttcttt ttcaccggta tttgccactt
    32701 gataatgaac cgtgatgccg tctcctccta attcatagct gatcactaat tcaaaatcaa
    32761 atggatactt ttctaatgtc tccggcgtac tccttaagat gaaactagcc atttcttgtc
    32821 catgttcaat gacttcaaaa tccatatccc gagcaaatcc gtgttgcccc atttgatatg
    32881 ttttcccttg ataaacatac tgatcatctt ttaaacgtcc aacaaaaggg aataaaaccg
    32941 gtgcatgtct gccccaatac gctggatcac cttgccagat atactctaaa ccatgttctt
    33001 ttgatttcag actgatcaat tccgcaccgt gttcagcgat ttcggcgatc agctggtcat
    33061 tttgaataat aacagtcatt gccattcctc caacttcgac ttacttttta aaatgggaag
    33121 gctggaacaa acatttctat ctgccccagt ccccttactt ctaataactg tgttttgcta
    33181 actcgtcttt aaaacgggaa ttcaatactt ttaaataagt tcccttcatg cctaacgaac
    33241 gagattcaat gattccagct gattccaatt ttcgtaaagc attgacgatc acagaacgag
    33301 tgatgccgat actatcggca atattagaag cagtcagacg accttcatct ccatccaatg
    33361 cttcaaagat agcttgtaca gccttcaatt cgctataaga taatgtgttg attgccattt
    33421 ggacagccgt tgcactccgt acatctgctt cgatgcttcg agacttctga taaaggatct
    33481 gcataccgac aaccgtagct ccatattctg ctaagactag atcgtcatct gcaaacgatt
    33541 gttccatacg agataagata atcgtaccca aacgttcgcc agctccaaag atcggaacga
    33601 cagtcgtcag accaaatgga tatttctctc ttgactctac cggaaatgca gtaatatcac
    33661 tagtaattgg gatattagct tcagttttca tcaactgtgc cactgtatca gtataagatt
    33721 caggaaattg tttctcaaca aacattgttt tgattcgttc attgttcaca tcgtgacgtt
    33781 cattataacc tagtaatact ccgtcacttc ctatgatata ggtgttgctg tcaagaatac
    33841 cacctagtgt gacagccatt ttatcgtaag gcaaatctgc ttgcatgtca aaagtattct
    33901 tttgctgcaa aagtgtgttt atcttgcggg ttttcgttag caagtctgtc attgtcgtcc
    33961 tccgattttt tataaaatat agcgacttaa atcttcattt gccgcaattg agccaagttt
    34021 gtcatccaca tatgcttctg tgatcgttat ttctcccatt tgcatatctg gtgcttcaaa
    34081 taatagatct tctagtagtt tttccaaaat ggtatgcagt ctgcgtgcgc cgatattatc
    34141 tgtgtcacgg ttgacatcga aagcgatttg agcgatccgt tcaattgctt cttttgtaaa
    34201 cgtaactgac acattttctg taccgatcaa cgcgacgtat tgttttacta aagcattatt
    34261 tggttcggtc agaatcttca caaaatcttc agctgtcaaa tcatctaatt ctacccgtat
    34321 cgggaagcgt ccttgaagtt ctggaattag atcacttggt ttagacaaat ggaaagctcc
    34381 tgaagcaatg aataggacgt gatctgtttg gatgatcccg tattttgtgt ttacttgtga
    34441 accttcgaca attggcaata tgtctctttg gacgccttct ctggatactt ctccagattg
    34501 ctgtgattta gaagtgatct tatcgatttc atcgataaaa ataattccac tttcttccgc
    34561 taatttgatt gcctcactat ggatatcagc atccttgact aattttgctg attcttcctt
    34621 gatcaataac tctaaagctt ctttgactgt taccgtccgt tccacttttt tcttcggtgt
    34681 caaagcacct agagtttcat ttaggtcgat ccccatttgc tccaatccat tgttcatcat
    34741 tggtgcaggt ttcttttggt cttcaacttc aatggttact tcacgactat ccagtaaacc
    34801 cttttgtagt tgttccaaga ctgtacggcg attgattcga atatcttctg tcacttcttc
    34861 ttgcggttca gcggtatttt gctgactagc attaaaaaga ttcatcattt gttcaaattg
    34921 attagtggat tgtttctgtt cttttttgat accaggtacc aagattttta ccaaacgttt
    34981 ttctgcattt tttttagcac ttgtgtatac acggctgtac tgctcttttt ctacgatttg
    35041 gatcgcattt tctactaaat cccgaaccat tgattctaca tctcttccga cataaccgac
    35101 ttcagtaaat tttgttgctt cgactttgac aaatggtgca ttgacgattt ttgccaaacg
    35161 tcgtgcgatt tctgttttac cgacccctgt aggtccgatc atcagcatat tttttggtgt
    35221 aatatcttgt tgcatttttt catctaactg caaacggcga tagcggttac gcaaagcaac
    35281 ggcaacagat ttttttgctg cgtgctgtcc tacgatatat tcatctaatt cacttacgat
    35341 ttgtcttggt gtttgtttta attcatacat atctactcac ctcttacagt tcttctacga
    35401 taatattatg attagtaaag atacagatat ctgcggcaat atttaacgca ttttctgcaa
    35461 tttctttcgc actcatgtcg ttttgagcat agtttttcat tgctcgggct gcagccaacg
    35521 caaaattccc tcctgatccg atagctaaga taccatcatc tggtgtgata acttctcctg
    35581 tacctgaaac aagaagcatt tctttatcat tcattacgat cagcatcgct tcaagttttt
    35641 gcatagattg ctgtgtccgc cattcttgag ctaattcgac agctgcgcgt tgtagattcc
    35701 cgttatattc gtttagtttg ccttcaaatt tttcttctaa agtaaacgca tctgcaacac
    35761 ttccggcgaa acctacaaca acttctccat tgtagatacg tcgtactttc tttgcagtgc
    35821 ctttcatgac aacagattca cccattgtta cttggccatc tccagccata gcaaatttcc
    35881 cgtctttttc gacggcacag atagtggttg aatgaaatgg tgattcgacc atgtttgttt
    35941 cctcctaaat ttgttctttt ccttattttt acgctcttgg atggaaagaa cgatagtttt
    36001 tttgtaaact ttcttttgtt acatgggcat agatctgggt agtcgataaa ttggcatgtc
    36061 ctagcaattc ttggactgtc cgcaaatctg ccccattatt taataaatga gtagcaaatg
    36121 tatggcgcag catgtgagga tggatatcac tatccaaact gctttttttg atcatttgat
    36181 tcaagacata ttcaattcca gtaggcgtga ttggttttcc atgatgattc acaaaaacga
    36241 tatcatgctc ttcgtgatat tttgtcatca atacctggcg gccttccctg aaatattctt
    36301 gcagagcatc ttgagcaaaa gaacctagag gagcatatct ctctttgttc cctttaccat
    36361 ggatcaacat gacctctgaa tcaaaatcaa tgtctgatac cgacaaactg ctacactcac
    36421 ttaaacggat gcctgacccg taaaggactt ccagtaaagc gcggttcctc aaatccaaag
    36481 gactatctcc tgctacgctg tcaaaaagtg cttgcatttc attttcataa aaaaaacgtg
    36541 gcagtctcaa atttttcttt ttgagatgaa cgtaagaaaa tggattttct tttatcactt
    36601 cttctttgag aagatactga taaaacgaac gtaggctggc tatcttgcga ctgatagaat
    36661 ttctgctata gctaggacga tgatcagcta atgcactcaa atagacacga accgtaaaat
    36721 attccgcctt cagcagatca gcgtctccag attcctccaa aaaatgtttg aaatggagaa
    36781 tgtcttcttc atatgcttct ttcgtttttt ctgaatatcc tctttcgaca atcaaataac
    36841 gcaaaaattt ttgttcccac gtggcttctg tcattttctc accttccttt tgtcccagag
    36901 aataatttag cacagcgttt ataaaaagac aaataaattg tcagaattta accaatattt
    36961 ctaagtttgt tcacaattgg cgcaattcct cacattttgt ttgagaaatt cttaagaaaa
    37021 acgcaagaaa aagagcgaga ctatccgtct caccctcttc atggagtttc cttactcatt
    37081 tgggattgca gttttttcta attctgtttt tattgcctca ttagctttta aagctcgttg
    37141 tgcaattgct tcatatcttg cttttttgtc tcgaatgcgc tctggcagtt caggaaacag
    37201 accatagttg gcattcatcg gttggaaatg ttttccttcc gcatgagtaa tgtagtaagc
    37261 catacttcca atagctgttt cttgtggaaa ctcgactggt tccatttctt ttgctaagcg
    37321 tgcggcgttg attccagcaa gtagtccgct cgctgcactt tcaacatagc cttctacacc
    37381 agtcatctga cctgcaaaga acagatcttc gcgtttcgtt gattggtaag tcggtttcag
    37441 caattctggc gaattcataa agctgtttcg gtgcatcaca ccatagcgaa cgaattcagc
    37501 attttctaac ccaggaatca tccggaaaac acgtttttgc tcgccccatt tcaagtgagt
    37561 ctgaaagccc acgatgttgt ataaagaagc tgcagcattg tcttgacgca gctggataac
    37621 agcataagga cgtttgccag ttttaggatc ttccaatcca actggtttca taggtccgaa
    37681 aagcatcgtt ttgaatcctc gctgtgccat tacttcaatt ggcatacatc cttcaaaata
    37741 tttttctttc tcaaaagatt taagttctgc cacttcggca ttgattagtg cctcatggaa
    37801 agctttgaat tcctcttctg tcatcggaca gttcaagtaa gctgcttctc ctttgtcata
    37861 gcgggacttc aaatatactt tatccatatc gatcgtagct ttgtctacga ttggtgcagc
    37921 tgcatcatag aaataaaaac catctgaacc attgaatgct ttgatgcttt ctgctaatgg
    37981 atgagaagtc aaaggtcctg ttgctactac ggtgattcct tccggtattt cagtaatttc
    38041 ttcgtttatc actgttacta atggatgctc tttgactttt cgggtaattg tttcagaaaa
    38101 agaatcgcgg tcaacagcta aggcaccacc agctggcact gctgtttcat ctgccgaagt
    38161 gattactacc gaattcaatc ggcgcatttc ttctttcaat aaccctactg cattagccaa
    38221 actgtttcct cttaatgaat tggaacatac tagttcagca aaattacttg tgtgatgcgc
    38281 ctcagtcgat ttgactggac gcatttcata taaacggaca gggactcctg cttgtgcgat
    38341 ctgccaagca gcttcacttc cggcaagccc tgctccaaca acatttacca ttttcaatga
    38401 aagaacctct tttctattat ttttggatgt cttcttcgta atctccattt acacagacta
    38461 cttgtttacc gcctttgact ttcttctcga ccagatatcc gtcacatttt ggacaatttc
    38521 tgcccactgg tttatcccaa gaagtgaatt cacattctgg gaaacgggaa caaccataga
    38581 atagtctgtt tttcttagat tttcgttcaa tgacttgtcc ttcatgacat actgggcaag
    38641 tcacaccgat ttcttttacg attggtttcg tattccgaca atcaggaaaa ttactgcaag
    38701 cataaaactt cccatatttc cctaatttta tcaccatcgg atgtccacag acatcacaat
    38761 cgaatcctgc tggttcatct ttgatttgaa ttttttcgat tttttcttcc gcattcgtca
    38821 gttctttttc aaacggttta tagaaacgat caaccacttt gacccacgct tccgtgcctt
    38881 cttcaatttt atccaaatct ccttccattt ctgctgtgaa atggatatcg acgatttgag
    38941 ggaagaattc acagattaat gaattgacaa tttctcctag ttcagtcggc tcaaatcttt
    39001 tttgtgtcaa ttttacatag tagcgtcttt ggatcgtatc aagtgttggt gcataagtgg
    39061 aaggtcgccc taccccgttt tcttctagtg cacgaatcaa cgtagcctca ctaaaacgtg
    39121 ctggtggttg agtaaaatgt tgttttggtt caatatcaac agattggact acatcgcctt
    39181 cttcaagttc tggaagaata ttttctttct cttctttgcc gtcatctcta ccttccacat
    39241 acacttgcat gaatcctttg aatttgattt ttgaaccgtt cgcaatgaag atgacaccat
    39301 tttgttctaa tgtcactttc attgtatcta aaatagctgg tgtcatctga ctagccacaa
    39361 aacgtgacca gatcaatgta taaagtttca attgatcttt atctaaatat tgtttgagtt
    39421 catctggtgt acgaagcaca ctcgttggac gcacagcttc atgggcatct tgtgcgcctt
    39481 gagcattttt gatctttcgg tgatcatgtc tagaaaattc ttttccatac gtatcttcaa
    39541 taaatgctgc ggcctctgct tttgctgtat cggcaatccg ggtagaatca gtacgcatgt
    39601 atgtaatcaa gccgactgtt ccttgtttac ccaaagtgat tccttcatat aattgctgtg
    39661 ctaccatcat ggtttttctt gttcgaaagt ttaacttacg ggcagcttct tgttgcaggc
    39721 tacttgtagt gaaaggattc gcagggtttc ttttgcgctc tttcttttct acttttttaa
    39781 cttcgaagtc tgttccatca attctagcag tgacttcttt tacactttgt gcatctggta
    39841 atttcttttt cttaccgtcg attccccaga aatttgcttt gaatttcttg cgagcttttt
    39901 taaaattacc gtcgatgctc caatattctt ctggaacaaa ttctcggatc tctttttcac
    39961 ggtcaataat aatttttaaa gcgacagatt ggacacgtcc tgcacttaac cctttcttga
    40021 ccttacgcca gagaatagga ctgatcgaat aaccaacgat tctgtctaag gtacgacgag
    40081 cttgctgtgc atctactaaa tctacatcga tcgttcttgg ttccttaaaa gctgctttga
    40141 ctgcgtcttt tgtgatttca ttgaagacca cccgattttt ttctttcaga tccaacccaa
    40201 gtaggtacgc taaatgccaa gcaatcgctt ctccttctct atccgggtca cttgccaagt
    40261 aaactttttg agcttttttt gctgcggctt tcaggctttt gatgacatcg ccttttccgc
    40321 gtatagaaat ataatggggt tcataattgt tttcaaaatc gatacccatt ttacttttcg
    40381 gtaaatctct tatatggcca acactggcca ttactttata gtttcgtcca agatatttct
    40441 caattgtctt ggcttttgca ggtgattcta caatcactaa atatttatac gccattactg
    40501 aatggactcc tttccattgt cgtgttccta ctattaaaag aggattcata caaatcgtag
    40561 ctaatcatat ccattcagaa aacgtttgtc aagaaaagca aatgaaaagt atggtgttat
    40621 tctttaaatt ctgccaagat atcttcaccc gaaaccgtgc aaactgcacc gtcttggatc
    40681 aaatgatgac atccggtaga atgttctgtt aaaatatttc ctggaacaga aaaaactgtt
    40741 cttccaagat ccaatgcttg ctgtgctgtt atcagagagc cgcttttttt cttggcttca
    40801 aagacacatg ttcctttaga caaagctgcg ataatccgat ttctcattgg aaaacaatgc
    40861 tttttcgggc cggattgagg aggatattca ctcaaaagaa gatgatcatt tgcaatcacc
    40921 tcttgcaagt cacgattttc agcaggatag acttgctcta tccctgttcc aatgactgcg
    40981 attgtccgtc caccatgaga gattgctgct tggtgaccgt atgtatctat ccctttcgcg
    41041 cagccactga cgatcacata tccagcttct atcactggtt ttagtaaata ataaactgtt
    41101 tttttggcta aagcagaagt gtgtcttcca ccaacaacgc ttaacatgtt acaagaaagt
    41161 aaagatagat caccattata aaacagtaca attggcggat aggtcaagtg aagcagctga
    41221 gggggatatt tgggatcaaa gcaagtgata aacgactgtt tcgattggat tttgccccag
    41281 ttagcgtgaa tttcctgcca acttttgcga aacagctccc ggtgtttggt tattttacct
    41341 atcttaatga tgtcttcaaa tccgatttct ttataaggat actgcatcat ccagttagca
    41401 agtgcccatt ttccttgact actgattcct tttgtataag caagtttcaa taaattttct
    41461 tctatttgat acatcataaa accgcctttc gtctctcttt ctaataagat acgtaaaagc
    41521 ggctgttttt tattgtaaat atttttttac aggtgcaaaa cttttacgat ggattggcgt
    41581 aattccttgt cgttcaagtc cttctaagtg ttcctttgtt ccataacctg cattatgcga
    41641 gaaaccatat ccaggataaa gcacgtcata ttctttcatc aattggtctc gatatacttt
    41701 agcaatgata cttgcagcag caatcgacac agatcgtgca tcccctttga ttattttttc
    41761 ctgctgaata ggcaaatcca aggtcatcgc atcgatcaac aaatagcttg gtacaatgga
    41821 caatttttct actgcttgga tcatcgctaa tttacttgct tcataaatat tcacatcatc
    41881 gattgtctgc tgatcaacga tcccgatccc gattgccagg gctttttctt gaacttgttg
    41941 ataaagaagt tctcgctttt tctctgataa ttgtttggag tcattcagcc ctaatatgat
    42001 ctcatttttc ggcaagataa ctgcagctgc cacgacaggt ccagctaatg gtcctcttcc
    42061 tacttcatca atgccggcaa tccattggtg accttgtgcg tacccttgct tttcaaagca
    42121 aaacatttct tcatattttt ccttaattaa tgcttccttt ttcaatcgtc gttcaaaaga
    42181 agccagtgct tgctgcacgc ctttgcgtgg atcatttctt aatgattcta gtgtaggatc
    42241 atctattctc tgtatgcttt tcaatcgttc tttgatactt tggatggatt cagtcatcac
    42301 ttttttgctc catttcttcg caacgatcca gtgtgtatcg tccaagtttt ccttgacgaa
    42361 tatcatgcac gactaattcg ctgccacgat catagtcttc tttataccca cgttttgctg
    42421 taatatccat cagtaattcc ggtgccaatt tttcttcttg ctcgattgat aaaccataac
    42481 gatcgctgat tcttcctgaa taatatcggg caaaaaagtc taatccgtaa atcgctaaat
    42541 catctaaatg gacaagctgg tctttgatcg cgcctgtcag cgctagtttt ttgccgattt
    42601 cttcatcttc aaatttgggc cataaaatcc ctggtgtgtc taacaattcc aactcattac
    42661 ctaaacgaag ccactgctga ccttttgtta cgccaggctt atttcctgtc tgtgcaattt
    42721 tcttgcctac tagtcgattc atcaacgtag atttcccaac atttggaata cctaagacca
    42781 ttgcccgaat agcgcgaggc ttgatccccc gagcagcatc tcttgcccgt ttttctttca
    42841 atgcttcttt agccgcaggt actagacctt taattccttt actttcttgt gccgtgatag
    42901 ctaatgcaag atggccttgt ttacgaaaat attcttgcca cagctttgtc tgttgtggat
    42961 ctgccagatc cgctttattc aataaaacaa ggcgaggttt ttgctgaatg atctgatcta
    43021 gcattggatt acgagaagat aaaggtaatc gtgcgtctac caattcaaat acgatgtcca
    43081 catatttcat tttttcagaa acttctcgtc gggcttttgc catatgtccc ggaaaccatt
    43141 ggatggtcat tgttctctcc attcctttca taccggaata ttccccggct ttacttgttt
    43201 ttttcttttt caatataaat tcactttttt attataaaga aattccatct attagttaag
    43261 tgaaagtgaa ccagtcctca ttctatcaca tcttcacttt tttgatgatg caaattttta
    43321 ttttggtttc tatatatgaa tctaaatttt tgacagcgtt tcctaaataa gagatgatag
    43381 acgaacaaaa cagaaaggag acgaaacaaa tgaatagtat ggtttttgtt aattttcctg
    43441 ttgctgatgt caatcgttcc gttgcttttt atgaaaagct gggttttaaa aaaaatgaag
    43501 aattttctac tgaagaagct ggttcaatgg tatgggatga cactttttgg ataatgcttc
    43561 tctctcatga tttttataaa aaatttataa aagataaaga aatagctgat aataaaaaaa
    43621 caagtggtgc tttgatttcg tttagtgttg aaaatgcgga tgaagtaaaa aaatttgctc
    43681 aaattgcaaa agaaaatggt ggtactttcc acgaagtaga tatgggaatg cctgaagaag
    43741 aaatgttttc attagaagtc caagatctag acggaaatac attagaaccc gtatggatga
    43801 agatgtaagc agataactaa tctgacgttt tttataacaa aaaaacaaag gcggatgata
    43861 cgataagtat tctccgcctc tatttttttt attcgtacaa tctctttttt acagtttata
    43921 aaagcagtct tctcaccctt tttttaattg ttagatgcca gtgtatgtaa atcaccaatg
    43981 tgtcatgaca cattggtgat tttatggtat ccttttatta ttaactgaca aaggagagaa
    44041 tattttgaac actttgattg caaaagacgt ttttagattg cccgaaatga atgcaagatt
    44101 gttgtcgacc tctgctcttt tattagccct tgatgtcatc ttatacaaga tagcgattgg
    44161 tcctgcttat tttcaaatca cattcggatt tttaagtatg gcgcttatgg gttatctata
    44221 tggaccgatc tgggctggtt tgcttgaaat gttgtcgaac actttaaatt tcacgatatt
    44281 tggttcagga acgtttcaag ctgcttttct tatcacggct ttccttggtg gatttattaa
    44341 tggcttattt ttatatcata aaaagataaa cctgccttcc gtcatcgctg cccaattatt
    44401 gattatgatc ccagtcagcc tttttatcaa ttcttggctg atgtctgttt tgtttggtgc
    44461 agatttcaaa gtaatttttc taggtagatt catcaggaat atgatccaaa tccctattca
    44521 aataatggtt gtttattcat ttatcaaaac tttagaggct agaaaagtgt ttaaacgagc
    44581 tgtttgattt tacgtactaa ggtagtaaac tgattttgga ttaaacaata aagcgtgcag
    44641 tctcaacaga ctgcacgctt tattgtttct cactggatcc attttatttc atcaagtgga
    44701 taatagacaa atcttgcttt acctagaata tcagttttat tgatcgtgcc aaacgaacga
    44761 ctatcttttg aaactcttcg attatctcca agtacaaaat aattatcttc cggaagcttg
    44821 gattgtcccg ttagctcttg tagtgtaaag tccgtcgtat aggatgcatt tgcatgatct
    44881 gatttcaggt ttttagttag ataaggttcc ttaactactt tcccattgat cttcaattga
    44941 tcattttggt agctgacatt ttctcctgga agaccgatta ctcgtttgat ataaatcgtg
    45001 ccatctgcta attgaaaaac aacaatatca aatcgtctga tctccgaaaa tttttccatc
    45061 acaaccatat caccttgctt caacacgttt tccattgaat tgccttccac tggtaccggg
    45121 atgaataaaa atccccgcaa catgaacgca aggaatacag aaacaagtaa gtatttgaat
    45181 acaagccaga agcgattaat atagcgttgt ttttttgtca atctctatca atccatccct
    45241 ctttttttca ttctttcttt attataagaa aaatatcaaa aaaatgcgac tagatagctg
    45301 aaataaaaat aattctttca attaggctat tggacaaaaa acttttttga tcataaagta
    45361 caaaactatc tcttatatgt catgattatt ttctaaatat ttttcccatg cttcgtcaaa
    45421 gatatccatg gacggcaaat agtcgacatt cagttccaga taattagaaa tttcttcgta
    45481 gctagagctg tgcttaggaa attggatgtc tttaccggct tctgtagcga aaacagataa
    45541 agcatcatgt gtgccaccgc ctcgcagtgt cattaaataa tgaaaaaagc ttcgattcac
    45601 ccttcgttcc tccaattttc ttcgataaag gcagcccggc gtgcatggtt tcttttaaaa
    45661 ttttcaggat gctttttata atactcttga tggtcttctt ctgctagata aaatggttgg
    45721 gctggttcga tttttgtaac gattggctgt tcgaaacgtc cactttcagc taactgtttc
    45781 ttactttttt cagcaatgat ccgctgttct tctgtcaaat aaaagatcac cgggcgataa
    45841 ttgtcaccgc gatcctcgaa ttgtccgaaa gcgtcagttg gatcagtttg ctgccagtaa
    45901 agttctacta attgttcata tgaaatcaat gttggatcat agataatctc cactgcttct
    45961 gtatgtccag tcgtttggct ttttacttgt tcataagtcg gatctggtac atgccctcca
    46021 gtatatcctg acatcactgt atggatacca ggaagcgtgt cgaaaggctg gatcatacac
    46081 cagaagcagc ctcctgcaaa tattgctcgt tccattatga ttccccctct aatactactc
    46141 atccgatgat tttttatttt cttttgtctt gctttcagta ctgctggtgc tagttttgtt
    46201 ggtatttgag ttgtttgaag catcagaggt atcttttggc aaatatagac taaaccgaat
    46261 gtcatcattt actaagtcga ttttatctgc tttaatatac atcccgtttt gcattcggaa
    46321 ttgatccaac ctaagcatga tagtcagatc atctgtattg acttcgatcc aatctggtaa
    46381 tttatagttt ctcttgatca tattcatcac atctttgatt ggcaaactca atgttccgat
    46441 agaaagactt ctagctttta gttggacatt tccgttttcc atcacatacg gatcaaaata
    46501 taaatagaaa tcgataggaa aacctagtac ttcgaaagta ccattgagta gtgcttcatt
    46561 ttccaaataa aatttatatt caatatcact atctttttga tactcactaa ggaaaaagct
    46621 gatgatttga ttgacttttt ctttatttga attgatcgtt aagacaggat ctccttgtct
    46681 ttccgtaaga gctggtattt ctgggagttc tggttcccga ttagcaaaaa tacggctgcc
    46741 taaaaatacg gtcgaaccaa gtactacccc aagaaggata aggaaggcga atttccagta
    46801 atttgttttc tttgttttgt ttgaagatac gtcagatctt gttttcatgt ttattgatca
    46861 tcctccttct ctaaccattg gttttgtgtc tcgatcagct gatctctcac tgcatttgcc
    46921 atcaattgat aacctaaatt atttggatgg aaatgatctt cttcatagag cacattattt
    46981 ttgatgccat ttagattttc tgtcgtgcta gttgtttgat ctgttccttc ttctgtgaca
    47041 cctacttcct gattcaatcc ttgataaagc aaatcattga ttgggataaa gtagcagttc
    47101 ggcatttttt ttgtcaccgt ttctgttcct ttgttccaat tgttaacaat tgtctgcatg
    47161 tcagtgatct caggaaagtt caaataaaat ggattgtaga tgcctaaaat gtaaataggt
    47221 gcggttttat tgagggatcg aaattcttcc aatagttctg tgacattttc ctgatagttt
    47281 ttcagtggct ttttaaagga attgaccgtt aacccgaata aattattttg gataactttc
    47341 atcaaatcat taccgccaac agtcagtgtg ataaaatcag ctgttttgat attgtttcga
    47401 atttcttctt ttgtttttac tcgctttaag atctggtcac ttcgttcacc atttacacca
    47461 tagttttctg tttcaaccgc ggtcaaatta taacggtctt ttagatcatt tgcgacaagg
    47521 ggaacgaatc ctccttgctt ggtttgatct cctactcctt cagtcagcga atctccgata
    47581 gctatgtagt gaagtttttc ttttttattt ggatcttctc tcacagtagt tactggtttc
    47641 attagtgggc cagctttcgg tatagaagca gctaaacctg catagatgat gatcgcaatt
    47701 aataatggga acaaaacgag gatcaaatgt cgtttcgtta atttcatttt ttcacctctt
    47761 gtattcgatt ggttctaatg ttatcaaaaa ttttatcaaa aaggtagtct ttatgaaaaa
    47821 agaaaacaat tattttccta attttataaa gaaaaagaga ataagctgca agcctttcag
    47881 gctgagggct tatcctcttt tcgactaatc tacataatac atgattgcaa acgcgtcttt
    47941 accagtatgc gtagcgataa ccggattcgt atgcagtaca gggatatgca tgtccgggaa
    48001 taattcttgc aaaccctctt tgaattcttg cgccaattct tttgcatccg catgtgaaat
    48061 accgatttgt cgcacatttg gcaattcttt cagttcattt ttcaaattat taaaccattt
    48121 atcgaacgtt ttctttcctc gccccttagt tacagggatt aattcagaat gggcgaaatt
    48181 catcaccacg cgtatgttca aaacactaga cagcaaacca gttgttcggc tgattcttcc
    48241 accttttacc aagttatcta gtgtggatat tccgatgtat aattttgtat tgtcttgtac
    48301 ttttttgact tcttcaagga ttttctctac tgttttacct tcttttgcta attcagctgc
    48361 tcgaattacc tgaaaagata atccttggtc agtggtatca ctgtcgataa ccgttacttt
    48421 cgtttttgtt agattactgg cttgtcttgc tgcttctact gttccactca agccttttgt
    48481 catatggatc gaaatcactt cactgccgtc ttctcctagc tcatcataca tcgagatgaa
    48541 ttctccaatt ggtggttggc ttgttttggg cagatttttt gctttcgcca tcatttccat
    48601 aaatctttcg ccgtctagtt ggtcatcatc gggatatact gttccgtcga tcatgatgga
    48661 tagcggcatg acacgaatgc ctaaagcatc gcgtacattt ttttccatcg tacatgaaga
    48721 atctgttacg atttttacat ttgtcattat tttctctctc tctttcttta acaagatgcc
    48781 ttattcatgt taaactacat gtaagacaat ttctattttt agtataacag acaaataatg
    48841 atttttcatt aattacacct agtaaaggag ccgttttcat ggaaaaaacg aaatttaatc
    48901 gaacgtatga aatattaaat gaagtgttta atgcagtcac ccatggaatt gggactggat
    48961 tgagtatcgc gggactagtg gttcttttag taaaaggtgc ccacttgcat tcctccctcc
    49021 atattgtctc ttatgctatc tatggatcga tgatgattct tttattttta acgtctactt
    49081 tgtttcattc attgattttt acaaaagcaa aaaaggtgtt ccaagtattc gatcatagtt
    49141 cgatttttct tttgattgca ggaagttata ctcctttttg tttgctgagt atccgaggat
    49201 ggctaggttg gactttattt gtattaatct ggttgtttgc gattcttggc attatatata
    49261 aagcgttgac gttgcataaa cgggagagag tatcaaaagt atctacgatc atctatattt
    49321 ttatggggtg gctctgtgtc gtggctgctg ttcctcttta tcactctctt ggaatgactg
    49381 gtgttatttt gatggtagca ggcgggcttt cttacacgat aggcgcattc ttttatagct
    49441 tgaattctat ccgctatatg catgttgttt ggcatttgtt tgttatgtta ggtgcaggtt
    49501 ttatgtactt ctctgtttta ttctttactt aataaaaaaa ataaagctat ggatgggaca
    49561 gctctaaata acagctagtc tatccatagc ttttttatat cgtcaattcg cctgtcccgc
    49621 tttttacagg attctcatta cgctgatacg tttcaaattg atgcggataa cgattttttt
    49681 catccatttc tccttgacta gtattgatca gtgaccaatc agaccagtca acaggtggaa
    49741 aataagcatc tccatcgaat acatgatgga tgactgtacg gtataatatc gtacaaaatg
    49801 gcagaaattc ttgataaaca gctgaccctc cagcgatgaa aaagataccg tctgtttctt
    49861 tttccagagc aagcacgtct tccacactat gcatgacatg cacgccttct gctttatagg
    49921 aagaatctct cgtcaaaaca atcgtctgac gattcggcaa cggacggcta cccatccctt
    49981 cgaatgtttt tcgtcccatc actagtgtat ttgcttctgt catttgtttg aagaatttca
    50041 gatcatttgg caaacgccaa ggaagacggt cttcttttcc aatcaatccg ttttcatcct
    50101 gtgcccaaat tgcagctaac attttctcat cctttctgat tctaaacagc gataggagct
    50161 ttgatcgccg gatgtgggtc atatccttct aattggatat cttccatctc aaaatcaaat
    50221 actgactgct tttcctgatt caaaactaaa gtcggaaatg cgcgtatttc tcggctcaat
    50281 tgttctttca tttgttcgat atgattgata taaagatgag catctcctaa tgtgtgaaca
    50341 aattcgccaa ccgctaaacc tgtttcatgt gcaattaggt gagtcagcaa cgcataactt
    50401 gcaatgttga acggaacgcc tagaaacaca tccccactgc gttgatacaa ttggcagctt
    50461 agccgtccct cttgaacata aaattgaaac atcgtatgac aaggaggcaa agccatgcta
    50521 ggaacatctt ccggattcca tgcagaaacg atcaatcttc tagaatcagg agtctttttg
    50581 attgcttcga tcacttgttt gatttgatcg ataaagccac cgtcttttgt ttcccagtga
    50641 cgccattgat agccgtagat gtgtccaaga tcgccgtatg tttcagcaaa ggaatcatcg
    50701 gttaggatct tctcgcaaaa aagcttgctc tgctttttat attcttcatt gaattcagga
    50761 tctgtcaaac atctatggcc aaaatcagtc atatctggtc cattatagtc tggacttttg
    50821 atgtagcgtt caaatgccca ttcatcccaa atatggtttt tattttgtaa tagatagcgg
    50881 atattcgtat ctccttttaa aaaccaaagc aattcgcttt tgatcaatcc aaaaggtact
    50941 cgtttcgttg ttaacaaagg aaaccctttt tgcagatcaa accgcatttg gtatccgaat
    51001 aagcttaatg tgcctgtgcc tgttctgtct tctttacgat gcccttcttc caacaatttt
    51061 cttcctaagt caagatacgc ttgttccatc ctttttcctc ctaatcttct acccattcac
    51121 tcaagtattc ccaccgtgcc attttttctt caagttgtgc ttctgtttca gatacgtcgt
    51181 tttgcaattc ttgtaatcga gtgaaattat ctccttgatg attcatctct tcttggagca
    51241 atgagatttt ttcttcaagt tctgcaatct catcttcaat cgtttcccat tctttttgtt
    51301 ccatgtaaga taatttcttc ttttcagcag gttccttgct ctgtattttt ggtttcgctt
    51361 tttcagcagg ctgctgggtc tctttttgct tcagtaaata actggacatg tttccgtaat
    51421 aaagttcttg ttttccgttt ccttggaata ctaataactt atctgctacc ttgtccaaga
    51481 aataacggtc atgggaaaca gtgatcacag cacctggaaa acttctaaaa taatcttcca
    51541 aaatcgtcaa tgttgctatg tccaaatcat tggtcggttc atccaataat aaaacattag
    51601 gttgctgaat cagcagtttc aacaaaaata accggcgttt ttctccgcct gaaagtttgc
    51661 ctatcagtgt cccatgcata aatcttggaa ataaaaatcg ttcaagtaat tctgctactc
    51721 cgatttgact gccatctgct gtttttgctt cttcagcagc ttcttgtaag taagcaatca
    51781 tccgtttatc tggtgccatt tcttcatttt cttgtgtata atacgcaaga tgaaccgttt
    51841 caccgataga cattgtaccg ctatccaggg gaattctgcc agctagaata ttaagcaatg
    51901 tcgattttcc cgcaccattt ttaccagtaa tacctagtct ttcccgagat tgaatcaata
    51961 aatctaaatg ttctagcagt gtttggtcat ttatacggta actgccatct ttgatttcca
    52021 gtactttttt ccctaaacgt tgtgtcgcta ggttcagctc taaatcatct tcttggttta
    52081 cttggtacaa gttctccttt agatcttcga aacggttgat ccgtgcttgc tgcttggtgc
    52141 cacgtgcctg tacgccagcc ctcatccaag ctaattcctg tttataaagc cgcttgcgct
    52201 tttcttcttg ttctacttct acacgatcac gttctgcttt ttctaagacg taagcttcat
    52261 aatttccttt atactcgtat aattttccaa atgaaagttc gaagattcgg tttgctactc
    52321 tatctagaaa ataacgatcg tgggtaacca tcaatagtgc gccacggtat tgtttcaaat
    52381 agttttccaa ccactcgatc gcttcataat ctaaatggtt tgttggttcg tctagtaata
    52441 gtaaatcggg ttcatcaatc aacacttgcg ccagactaac tcgttttttc tgaccacctg
    52501 ataaagtact gattttttta tctaattcac tgattcctaa tttttgcaaa ataatctttg
    52561 cgttggtatc tgtagtccaa gcatcttctt tattcatttg ttcttctgct ttagcataac
    52621 gtttttgcac atcagggtct tctccgtttt cccctagttc gatcaatgct tcctcatatg
    52681 ctcgaacagt ttggatcaag gggctgtttc cttgaaagac tgcttggaga acagttaatt
    52741 catcggaaaa ttcagctgct tgagaaagat aaccaatacg gtaatcagtt ggataaaaca
    52801 ctgtttgccg atcaccgtcg ctgctatcga taccggcaat aatatttaag agacttgttt
    52861 tacccgtccc gttcgtccca atcaacccga tacggtcttt ttcgtggacc aaaaaagaaa
    52921 tctggtcaaa caaatctttt tcaccataag tttttttgag gtcagttact tttaattctt
    52981 tcaacatgtt ccctccttat cttggatatt gtatcataaa aatagtgaac ttcaggaaaa
    53041 tttttttggt atttgttctt tttgtgttct caaaaaaaga acaggaccga ttcgatcctg
    53101 ttctgatatg ttttgttttt tataaaactt gaaaattttt acctttttat tttattggac
    53161 tcgttttttt tgactttgct cgaaacgcaa atcggaaaga aaagttatca gatggtttgt
    53221 tcatcgtata agattctaac aaattgatat tcctgcgata gctgttcgca gaaaacgtcg
    53281 tgattttttc agcaacttcg tattcatcaa tgatttttct ttcaagataa taacctctta
    53341 gcattttttt cgtaaacaga ctatcttgct ggatcatcca cgaagaaatc aaattccccg
    53401 agttcatttt tattccttca agtttgcgtt gctggataaa aaattgaacc atcgtttcat
    53461 cataaatatc agtcaagtta tctaaacttt caataatcaa ctgagtattt ttttgatatg
    53521 tctctctgat ttcttggata tcttcatcac taataaatgt ctgacgatca gcatatcttc
    53581 tttgccaaaa cattttcgga tggagaacga ttcgcattaa cctacggaca acaatgaacc
    53641 aaaagccgat aaaagacaaa atctggcttg tgatagaatg ttcgaatcga gaaagaaaac
    53701 gggagtaaaa acgataacca ttagaagaaa gcttgcccga acgataactt tcatccaatc
    53761 catcccgttc gatcgacaaa atcagtgctt gtatttcttg tacttcttgc ttttcatcat
    53821 cggttaaatc ttccaagtac agatcacgta tccgttcttg ataattttct atcactgctt
    53881 cagtggctaa aaattctttt gtattacgat caatttcctt tatttctttt cgcaaaactt
    53941 caacgacctc ttctaaaatc atcaaagcat tcaaatccgt gcttttcgct tcctctgttt
    54001 ccgtcagcat aggcaagaca atgatcccta tgaccaaagt cactaagatg acacccgccg
    54061 tcagaaacaa aagcaaagac cgctggtaaa acatcatatt attgattgaa aatggcaaaa
    54121 taaaaatcgt agccaaactg actgttccct ttacaccgcc aaatgttaag atcaagatct
    54181 cgttcaactg ttttttgaac tttttactgc catctttgaa tacataaaaa agactgatag
    54241 aaatgaatct gatcacaaaa agcatgacag agattaatac gataatcgct aataaaagac
    54301 cgtttggata taaaccgtct ccccatactg gcgagaacac ttgcgtcaat tcgattccta
    54361 aaaatataaa tactaatgca ttcagtgtaa aagcaatagt tgtccatgta ctgtgggaca
    54421 agctcgacaa ttctgcatca aacacagaga ttttcctaaa accagaagct tggagaatac
    54481 ctgctgccac tgcagcaatg attccagata catcaaatgc ctctgccaat acataggcta
    54541 gaaaaggaag caaaagttcg atcagcagat accctgtgac atcttgtgct gatgcttttt
    54601 cgatcaaatg aattattttt tgtttgaacc agacaagcaa aaagccgatc aaagctcccc
    54661 caatactaga aactactaga ctcatccccg cgtttactgc tgaaaaagat ccggtgatca
    54721 gcgcaccaag agcaaactgg aaggcagtaa caccagatgc atcattcaaa agaccttctc
    54781 cttccaaaat atgcatcgcc tttttaggga tattcactcg tccagaaaga gaactgactg
    54841 ctaccgcatc tgtcggacct aacgctgctc caaaagcaaa gcaggcagca agtgggacac
    54901 ttggcaacag gaatgataac gtcgcaccta ccccgacaag ggtcaaaatg actcctccaa
    54961 atgccaagaa caaaattgtc ccgaaatttt tgagaatcga agaaatatct gctttttctc
    55021 cttctctaaa taacaatggt gcaataatca taactaagaa caattcaggt tcaaaatcga
    55081 ttgattgtcc ccactctgtc agacctaata ccactccaag gaaaatttgg atcagtggag
    55141 ctggaatcat tggcaaaatg cggctagcta tgttcgataa ggtgatcgtt actgcaaata
    55201 caataactaa ctcagcaaat tccatcgtcc atccccttta ttttttattt tgtgtaagca
    55261 tttttaaaaa ttgttctttt ttctttaaaa ttttggtttc gactacttca acctgtgttt
    55321 ggttcccctc taattcacac tgtacacgtt ttgactccaa acgaagcaga tcatgtttca
    55381 gacgttccaa ctgacgatac atcaatatat ttcttttacg caacttacaa agtatttgac
    55441 ggcggtcatc catcgaaagg gcgccatagc gatcatgcaa cagttttttt tgttgttcaa
    55501 aactctctct cattttccag atctcctata cacaaacttc catcattata gcaaagttct
    55561 ttttggatga aaaatatttc attgtttcat cgtttattgc tagttagaaa tttccataaa
    55621 tttttcaacg cctcattcta ttccaaatag tatcagatat caagtaaaac ttaagaaaga
    55681 taaaagtttc tgacaaaagg atgtttactt tcccattcct gcctttcttg ttcttttatc
    55741 acaacaaaaa aatggggctg cgacaaaaat cttgtcacag tcccttattc tgaataaacg
    55801 gtgtggaaga gacagcctat cagtagtaat aagacacatc tctttcacag cctcattttt
    55861 gcgtaaaaat cgatttattc gaaaaattcc ccgtatacat cttctacacg ttgatctgga
    55921 ttgatcacga tatacaagtt acctgttttt tcgctgattt ttgttgattg atattgattg
    55981 tctaatcctt ctgttccttt atctagatat gggaagtaca caagatcagg tgtgccattt
    56041 cggtaaagga tttccattcg ctcgatatct tcgtatttca atgcgcgatt aaacatgccc
    56101 atttccagtc cgcctaggtt gatatcatgt gtcgcaactg cgtccccttc atggaagatt
    56161 tcgattttaa atccagcaca cggatggatt tcaacaaatt cactgccatt gattcgtcca
    56221 aaacttgttg tgatttgttt gatccaaaga tcgccgatat gacggcggtt gatcgtccag
    56281 gtttctccat ttctaaaata aaattttagc gctgtcattt ctttactcat taaaaagact
    56341 cctttatgat gtaatttatt cttgtactac ctcagtttag cacaaattta tgtaagtggt
    56401 cacatcttat gttttttctt ctaatgacgt atctgcccac tttaagtagc caacaaagct
    56461 gagcagatac agtctagtgt tttttaaatc aatttttctt tcgataaaaa atccaaaacc
    56521 tgttttttat cattttttat tctttgttct acgacggctt tttcagctaa ttgcaaagct
    56581 tcactaaccc acttaccagg tttttttcca gtttcttcta gcaagatttt accatctact
    56641 gctaattcgc ttaatgactt gataggtaaa cgatcatagg attctcctac ggcatccatc
    56701 tgaggtgttt cgtcaaaata gatcatcaat tcttctactt gcagtgcatg ttttttgcct
    56761 aagaagtaca attcgaatgg ttccaaagct ccagtttctc gttgtcgtag tccttggaca
    56821 agtgcttgaa cgtctttaat catttggtta gaacacttcc acgatttcaa aaaggaacga
    56881 atctcatttt cttttagatc cagttggctg atcaataatg cccatgcttg gctctcttct
    56941 ttcaatggga cggatggtaa ttcagcaaaa cgtaaaagtg cttcgccttc ttctttcaaa
    57001 ccgggacagc aaatgtagca ctctgtttca ataaatgcat ggattcccgc ggcccgttca
    57061 tttcccaaga gcatcttgat gaattccaca tttatacgtt ctacagatat tttacctaat
    57121 agctcgtggt tttctttgat ggcgtagaag gtttcttcct ctaatttgaa ccctagttga
    57181 ctgacaaaac gcaacccgcg catcattcgt aaggcatctt catggaaccg ctcatgagga
    57241 ttgcctacag ctcgcaagat ctgttcttct agatcttgca gaccatcgaa caaatcgatg
    57301 atttctccat cttctttcaa agcaaacgca ttgatcgtaa aatctcttct tttcaaatct
    57361 tctgccaacg aacgaacgaa ttcgacatga tctggtctac ggtagtcctg ataagttgat
    57421 tccgtccgaa atgtggtgat ctcatattgt tcatcatttt ctaataccaa cacagttcca
    57481 tgttcgatcc caatatctat cgtttttgga aaaagctgtt tgatttcttc tggaaatgcg
    57541 cttgttgcga tatccacatc atggattggc tggttcagca agatatcacg aacacttcca
    57601 cctacaaaat aagcttcata tcctgcattc tctaattttt tcagaactgg aattgccttt
    57661 tggtattcca gaggtaattg ttttaatttc atttttccaa cctttcctgc gtgtttcttg
    57721 tcctgagata aagactcagt tgcatggtga ctgtttgaca agtccgtttc agagtcttca
    57781 aggccaggac cacttcatct tgtttactcg tccttacgct caaagcgatt atggtctctt
    57841 tgattgaatt tttccatgtt tttttcaaaa acttcagtta agtcgatatt caatgaatta
    57901 gccatgatca tcgtaacgaa taaaacatca ccaagttctt ctgctaccga gttaactggt
    57961 tcagaagcct ttttgctttt ttctccataa gtgtggttga cttctcttgc caattcacct
    58021 acttcttcag ttaatcgagc catctgagct aatggagaga aataccccac cttgaattgc
    58081 tggatatatt catccacttc ctgctgcata ctgtataaag aacgcttttt atccatcttt
    58141 ttccctccaa aactatctta ccaaaacttt aacgcaaatc ctagataaga gcaattgaga
    58201 aaatcgaatt tccatgctac atttaggaag gaatttctaa atggaaattc tgtgaaaata
    58261 cataattgaa agctggaatt catatggtca aacgaaaaac agtaaaagaa gttcttttta
    58321 tcattatagg aacaagtatt tatgcatttg gtcttgttta cttgaacatc gctaatcatt
    58381 tagcagaagg gggagtctca gggatcacct tgatcttaag agctttattt ggtattgatc
    58441 cagcttatac gactttatta atcaacatcc cattgatttt actaggagga aagatcctcg
    58501 gtaaacgttc cttggcctat actgttctag gtacactttc tttgtcattc tttttatgga
    58561 tctggcaaag ggttccacta gaaatcaatt tacagcatga tctactgatc gtttctctac
    58621 ttgcgggttt agttgcaggt gtaggaagcg ggatcgtcta ccgcatgggt ggaacaacag
    58681 gcggcagtga tattatcgct cggattttag aacaaaatta cggcatcact atggggcgtt
    58741 ccctattggc atttgatatc atcgtcttac ttgcttcatt aacctatatc gacttgaaac
    58801 gtatgatgta tacgttgatt gtttcgtatg ttttcagtcg tgtgattgat tcgatcttag
    58861 atggcggata ttctgcaaaa ggtctacttg tcgtctccaa caaaagcgaa gagattgcac
    58921 cactactgat gaccggtctg caaagaggtg tgactttcct ttctggagaa ggcgcattct
    58981 ctggtaattc aaaaaaaatc atctatatgg tcgttagctc tagtgaatta actgaagcta
    59041 agaggatcgt ccacgagatt gacgaaaaag ctttcctttc aatcatcaat gtgcatgaag
    59101 tggaagggca aggctttact tatttgaagc cacagacaag attactgaaa aaactataag
    59161 aaaaaagaca aagataggct atgaggaaag attccacatc cagctgacct ttgtcttttt
    59221 tagtactata ctatttttaa ctaattgtta tgttcactta cccggttact tttcttttgt
    59281 gtctgcaaaa ggatctttcg gttaacttca tcagataatt tcaaaaaagc atccctatct
    59341 ccatcttcta gtgcttgatc gatttgagca taaagcattt ttagttttgc ctcttcttct
    59401 ttttcttgaa aatatcgttc aattaattca gtatcttctt cactgactga agaatcccaa
    59461 gaagaaaatg gattgtcttc taagatagat agatattctc ttgtctgcca agcattttcg
    59521 aatatacatt ccacatataa aggctttttc caattcaaac ggatttcatg aaaaatctgg
    59581 tctgtgtccg taaattcttt tccctgcaaa aacaatttca tgggttcccc ttcaacagat
    59641 agatcactga tctgcagtcc tcgatccgca aaattcgccc cttcaacaaa gtggacattg
    59701 cttaaaatcg cttcatgatt ggcaagataa ttcaagatcc aaaaaacttc tcttcggcta
    59761 aaagatacat gattgaccat ccacgttaaa aaattcttct tttcccgtac atcaattagc
    59821 atttttctca cctctctgtt aggtcatcta ataatgacag tgcctccata tctcctggtt
    59881 caagtgttaa ataataagtc aataattctt gcgctctttt cagctgccct tcttctctta
    59941 agaaaaaggc atactctttc aagaaatctg gttcatgtga tagttcatga taagcctgtt
    60001 catagtgtac agctgcaacg gtaaagtctt ctaattcatt ataagcatgg gctaggttcc
    60061 attctgcata aggattagca gtttcttcca tctgattgat cacttgtatc acatcttcat
    60121 atctttcatc atccaagtaa agattactta aagtaagtaa tgtttcatct tgtttgtctc
    60181 ctacttctaa agctttcagt aaaagttctt ctgctcgctg tctatcatgc agacggaaag
    60241 cattttccga ggccaggtga taaagttcga cttggtaagg attttctttg attccttctt
    60301 ctaacactgt ttgtgcttct tcaatcattt cttcttcttg aagagcttgt cctagatata
    60361 gatataacga ttgataatgc ggattaactt ctcgaagttc ttccagatag ttgattgcct
    60421 gctgattttc tttcaattga agattcgtaa aagctagctg gaacagtcga tcatctgtcc
    60481 tttcttcttt cagtgcttct tctaaaggta cgatagctgc ttcgaattct ccttgcatac
    60541 ttaaggattg tcctaaacgt tcctgcatcg agattcctga aatttcattt atcccgcttg
    60601 ccaacaatgt ttcataaacc actgctgcct ctttgaaacg atcaactgaa aaatacaatt
    60661 cagctagcgc aaactggatc aatggttcat caggaagcaa cccagctgct tctttcaatt
    60721 ttgcttcact cacttcaggg attccgataa cttggtacaa atcagctatc gccaataagc
    60781 tttgcggata gtaatcactt tgcttatcca ctttttccag gtattcaaaa gctaagtcga
    60841 tctcattatc ttcgattgca atttctgcta acgggatgtt cagtccgtca ttttctgggt
    60901 attggttgat cagttgttca aaaatctgtt ttgcttcgat caaaaagcca atagccagca
    60961 attcttcgcc tagttcagct aatatatctg ctgggtcttc ttttaatgct ttttctaaaa
    61021 agatttgtgc ttgtgacaag tcttcatctg ataaagcttg caacattttt tcgctatttg
    61081 tattcatttc aattccctct tatctcactg acgatttgtt gaaataccgt cattgttctc
    61141 aataattctt tttcgtttgg atgttggtat ccgtctatta tacctatttt ttctaaaaca
    61201 agtatttttt tgcttttttc tgccaaaaaa agaacttttt ccaaatactc catctttgaa
    61261 atctgttcca gccagtggat tggatagcca agcaagtcca gccacacaaa aaagtttttt
    61321 agttggaaat caaaaggata tgcttggaga ttccacacga aatgaaacat cattcctaaa
    61381 aattttttca tactagcaga aagtagatgg ccattttcgg tcagataaaa agcttgttca
    61441 aacagtttac cataatttga caggttttct gcctctaatt gataaaaata gatcatttct
    61501 tcgatcatcc cggcaaacgg ccgagtcgtt aattgctttt tatttggata gtttttatac
    61561 agattttgca aaaaacgatg atcacaaatc attccgcaac agataaaagt caaaaagtca
    61621 atctgctttc cgtccacctg ccgctcgctg attgtttgat cataaacgat gcgttctggc
    61681 agattgatgg tttgcagcac tacacgattt ggtagctgca aaatcgtccg ctgcggtgtt
    61741 aatgctcggc ttagagaacg gatcgataca gggatcatcc atagtgatga atcaagggtt
    61801 gtatgttttt gaaaaaaacc tgccagatcc atgatccctt catttccaaa tccgatgata
    61861 aacatggatt gattttcggg atagcgtttg acgaaatcaa gcaggttctt taattctgtt
    61921 aaatgattgc attgagtgtt ggcacaaata taccagtcat tgtttgcttg atttgcaaat
    61981 aacgggttga tcttatctgc aaacaaatca taatagcgct gattcgttaa aaataagatt
    62041 ggctgatcaa tggaaagttc tcttagctga ctgactagcg tttctccgta aaacactttc
    62101 gtcaacgcat cttctacttg ataatcaagt tccatacgca tccctcctct tcttattttt
    62161 attttaccat tagtaagcaa attctagaaa agataagagc aaagctcacc tcataacttg
    62221 caaataaata aaaattaaat aaaatacatg tgttttctat gtatgacata cggattcgga
    62281 atctctgtct cttatttatt ccttttctgc taggaaataa aaagaaaagc acttgtagcc
    62341 ctagagccac aagcgctttt tcaactgtct tatttaacag cgtcttttaa tgctttacct
    62401 ggtttgaatg caggtacttt gctagctgga atttcgattt cttcaccagt ttgtgggtta
    62461 cgacctttgc gagctgcgcg ttcgcgaact tcaaagttac caaaaccgat taattgaact
    62521 ttttcgccgt tagctaaagc atcttgaata gttgaaaata cagcatctac tgctgcagtt
    62581 gcatcttttt tagttaaatc agtagctgaa gcaacttttt cgattaattc tgctttgttt
    62641 gccatggata gattcacctc ctccacaaga gatatgatag aaatatcatt tagttaaaac
    62701 tttctgagtg gtccagaagt ttaaaaagaa atattgatta acttcaatat tctgttatca
    62761 cgatatcata tgaaccgctt aatagcaagg tttttaccaa ttttcacatg ctttttttag
    62821 tcatagaaac gtaacaaacg aaactgtctt tttcttttga aaaaaaaacg tcgatatggt
    62881 aaaatgccta ttttctccta cgagggataa ttcggatgga cgtcccttca aaagtaaatg
    62941 cttttctgat ttgattttct aagaaacgtt cataagaaaa atgcatcaat tcctcttcat
    63001 tgacaaaaac gacaaatgta ggtggtttga cagcgacttg tgtagcataa aaaatcttca
    63061 ggcgttttcc tttatctgtt ggtgttggat tgattgctac agcatccata atgatatcat
    63121 tcaacacagc cgaagagata cgaagattct ggttcatact tacttgttcg atcatttcag
    63181 gcagacgttc caaccgttgt ttagtcactg cagaaacaaa aacgattgga gcgtaatcaa
    63241 gataccggaa ttcatcacga atctcttgtt cgaaatcacg cattgtattg gtttctttct
    63301 ttacaagatc ccatttattc acgacgataa taattccacg accagcttca tgggcgtaac
    63361 ccgctactcg cttgtcttgt tcccgaatcc cttcttcagc attcagtacc atcaaaacga
    63421 tatcagaacg gtcaatggca cgcattgcac gcatcacgct gtatttttca gtattttcgt
    63481 atacttttcc gcgtttacgc ataccagctg tatctatcat taagaatttc tgaccacttt
    63541 cagaaacgaa gtgggtgtcg attgcgtctc gggtcgttcc ttcaatatcc gaaacaatta
    63601 cacgttcttc tcctaaaatc gcattgatca aagaggattt accaacattt gggcgaccaa
    63661 tcaaactaaa cttaatcgtg tcgtcgtcct cttcttcagt ctcttcagag aaatacttca
    63721 ctgcttcatc taaaatatca ccaatcccta gtccatggct tcctgaaaca ggataaggat
    63781 cgcctagccc taaggaataa aattcataga tatcgtttct catttctgga ttatctactt
    63841 tattgactgc taaaatcact ggtttattac ttctgtataa aattttcgca accatctcat
    63901 ctgcgtctgt cacgccttcg cgtccgctga ctacacaaat gattacatct gcttcttcaa
    63961 tcgcgatttc tgcttgatgc ttgatctgat ccataaaagg ttcatcgcca agatcaattc
    64021 cgcctgtgtc gatcacgctg aattctcgac ctaaccattc accttttgca taaatacgat
    64081 cacgagttac tccaggagta tcttcgacaa tcgagatacg ctcaccagcg atgcggttaa
    64141 aaatcgtaga cttaccgacg ttcgggcggc caacgattgc aattgttgga tttgccatat
    64201 tatttcctcc tcacaagttt ccaatctcac ttagtttaac gaatgcattg ccaactttca
    64261 agcatagatt gtcaattaaa cgaagtattt ttattcctta ttgaaatact aatcgctttt
    64321 caaaagaaaa actgagacaa aagcagctgc tttcatctca gtcacagata caaaatcaat
    64381 tatttttcag aatcatcggt tgctttttct tctacttctt ctttcaacgc atcacctaaa
    64441 atgtctccca tagtaaatcc agtattttct tctggtaatt cataagactc aacatttttt
    64501 ggttcttctt ctgaagctgg tttttcttct aaagctttga tactcaatgc aatacgatgt
    64561 tcttctggat ggatctctaa tactttcact ttcacttcgt caccttcatg aagcacttca
    64621 tgtggtgtcg caatatgttt atgtgaaatt tgagagatat ggactagccc ttctactcca
    64681 gggaacactt caacaaaggc accgaagctt gtcaaacgtt taactgttcc gtctaatact
    64741 gtgccaactg gagcttttgt atcgatttct gaccaaggtc caggctgtgt gtctttgatt
    64801 gacaaggaaa cacgttcttg ttcaggattg atagacaaca ctttgacatt tacatcatca
    64861 ttgacagcca atacatcact tggttttgct acatgactat gtgaaatctc tgagacatgg
    64921 actagaccgt caattccgcc taggtcgaca aatgcgccaa aatcagtaag acgtgcaaca
    64981 cgtccactga gaacatctcc ctcatggata gttgaaagaa tttctttttt cttttcttct
    65041 ctttcgtttt ccactaccgc tttatgcgat aagatcaaac gattttctga tggttcgatt
    65101 tcgatgattt taaagctcaa tgttttgcct ttatagtctg aaaagtctgc aacaaaatga
    65161 tcttccacca ttgatgcagg gacaaaacca cgtacaccga cgtcaacgac taaaccgcct
    65221 ttgacaacat ttgtaacagg tgcttcgatg accttgccct cttggaaatc tctttcgata
    65281 tcttcccaaa cttttttagc atctaaacgg cgttttgaaa gtagatagct gccgttttct
    65341 ttatctttgc cgatcgtact gataacgact aaatctaata catcaccgac ttttactact
    65401 tcgctgatat cttctaccgg caaagttgat aattcttttg ccggaacgac tccttcaact
    65461 ccagcccctt cgattccgac aatcacttgt ttgtcttcaa tgactaaaac ttcgccctta
    65521 acaacatcgc caacttttac ttcttgtacg cttttcattg cgtcttccat tgactggttg
    65581 ttctcttgat tttgatcaaa ttctgtcata acacttgtcc tcctaaccaa cattctgccg
    65641 taagtacggt actgttttta gtttaattga ttattcaaaa aaaataaagc gatttcgttc
    65701 gttttccttg aaaaaacaat tgtttttcat tttttttctt aatttaaaaa agaagataac
    65761 cttttttcaa aacaacagct tttattgctg caacgacttc tggaatcgat ttgccagtcg
    65821 tatcgatacg aacagcatcc tctgcttgct tcagcggaga gacgtccctt gttgaatcat
    65881 aatggtctct ttcctgtatc tctttcgtca gtgtttcaag atcagtcgga attccttttt
    65941 cttggttctc tttgaaacgt ctttctgcac gctcacttac gcttgctact aaaaagattt
    66001 tcacttctgc attcggtaat acagctgtcc cgatgtctct tccgtccatg acaacgccac
    66061 cgcgttcccc tatttttcgt tggacagcaa ctaattcttc tctgactttt ccatgtgcag
    66121 agacttcaga aacagctttt gtgacatctg gttgacggat ttctaaagtc acatcttttg
    66181 atgctatgaa tacatgctgt ccatcttctt gttgcgaaaa agagatagga tactttttga
    66241 tcagcgaaac tagcccttct tcatctgaaa aagatacatt gttcgtaata gctaaataag
    66301 ttactgcgcg atacatggca ccggtatctg tataaatata attcaattct tttgctaata
    66361 tcttggcaac ggtacttttc ccagatgaag caggcccgtc gattgcaata ctgatttgtg
    66421 tcatgatata actccttttt ctcagaaaaa aagccgcaaa gcgcggctat tattatttaa
    66481 ttcttaattc ttgaccaggg taaagcataa agttgtttgg atctaagcca ttcaattcaa
    66541 acaattgatc agtggtgatc cctgcacgct cagccacttg ttttggacct tcgcctgctt
    66601 gaacagtcgt tgttgaaccg gctgcagctg atgaagaagg tgttgtttct gctgcattgc
    66661 tgcttgaatc ccctgcttga taagttgcct cacttgagga agtcggtgtt gtctctgctg
    66721 caatactgct ttctgacgtt acacctgtat cttgagacac agtagattct tccgcgattg
    66781 tactagattc tactgttgaa gtctcagttg actcctcttt tgttgtactt gtagaacttt
    66841 ctactactga tgtcgaagtt tcagaagaag ttgctgctgt tgcattgttg cttgatccat
    66901 ttctgatcca gaaataagca cctgctggaa tagcgataca taagaccagt aaaatcaaaa
    66961 atagcgaaag aaataatgta tttcctttct tttgttgtct ctgagaactt cttgatgaaa
    67021 cttcatcatc tgtatcgtag attggttgtt cccatggttc ttgtgtttcg ttattttctg
    67081 tagattgatg tctatctttt ctgctcactg ttttacctcc taaactctat cgtgtgtatt
    67141 ataccatagg aaaaagtgtc ttgtcctaaa aaatcaatgt tccatgtttt ttttaaataa
    67201 atttagtaaa atcgttcccc aatgaagttg ttcagtctta gaaaaaagct tcctctttgg
    67261 cagaagttct gcttttgctc catcaatatc acaacaattc tgcggctttt cggagagttt
    67321 ttcgccaaaa taagctaaga tgaattttct gcggcagttt tcttcattaa tatagcgaag
    67381 catctgctgc aggcggaatt ctttttcttt ttcctgacgt ttgagccgtt ccacccaatt
    67441 ttctggtttt tcagactgct ggatcagctc catccatttt ttttgcagct catcaaaggg
    67501 agcttgctct gtggcatatt ccaaataaag ctcaaaactt tgtcgctgtt ctctagaaag
    67561 ttgattaaag aaataatgga tacgttcatc cccactttga taaaaaagaa ttgctgcact
    67621 ttcttcctga tctctgcctg ctcgaccgat ttcttgtaca tagttttcta gactgtctgg
    67681 caaatcataa tggaccacat aacggatatc agatttatcg atccccatac caaatgcatt
    67741 cgtagcaatg agaaactgca gctgattttt tacaaactgc tgttgaagtt gtcttctttg
    67801 agctgcatca agaccaccgt gatagtatcc aactgtaaaa cgttccctga ataaatgata
    67861 caatcgttcg acttcttttt ttgttgcaca ataaatgatt gccgctcctt gtgctctttc
    67921 catgaagtgt tcaagttctt gttctttttg ctgcgttttc cgaacaaaaa gcgagatatt
    67981 ttgccgattg actgattgtc tgatctcttt tggtggtcga tcaaatagta catgacgtat
    68041 atctcttgct actaaatctg ttgctgtcgc cgttagtgcc agtgtgaccg ggtttcctaa
    68101 aagctttcgg atttttccta actgttgata ttctggacgg aaatcaactc cccattgaga
    68161 cacgcaatga gcctcatcta ctacatataa cgcaatattt tgttttttca gatgctctaa
    68221 aagagaagga ttagtcaaca tttcgggact caaaaacaaa aatttatatt gcgatagatg
    68281 acggaggacg tatcttcttt cagattgcga aagtaaacta ttgaaagcag ctactcgttt
    68341 ctcccctcgt ttttgtaatt gcgtcacttg atcttccatt agagaaagca gcggtgacac
    68401 gatgatgacc agaccttcca ttaaataccc cgtcaattga tagcaaaggc tttttcccgt
    68461 tcctgtaggc aaaatagcga gagtatcttc tccatcaagc aacgcctgaa taatttcttc
    68521 ttggccggga cgaaatgaat caaatccaaa atattttttt aattcattta ttaacattct
    68581 gtatcgcttc ctttctcaat agatagattt gatacaaacg aaattctcca taatctaatt
    68641 gtccatctac attccattcg ctaaagcgcc actctcgcac ggaatcctta tttggttcca
    68701 aacgttcgat tgtttctgca gagagaatcc actcgtatgg aaaatcatca aaaaacaagg
    68761 cccactcaat aagatgatct gttactgttc ctctttttaa atgacggatt gccatgatct
    68821 ggtcaattgt ctgaccattc ataaacatct gcttggtgat catcatgctt tgattgaaat
    68881 tttgctgtaa taatgaatcg atcaaagcgt gccaaagcga atctggccgt ttttcgattt
    68941 gtgctaacaa aaggtggata catctgcttt gttgcagata aaccgctgac tcatcattgt
    69001 tttttgccag ctgataagga agcagccctg ttcgctcatt tccagataat tggttagcta
    69061 aaaaatctgc tgcttcttct ggtatctccg aaaacagctg caccaaactc tcatacgcag
    69121 tatcaatcaa aatttcacgt ggcaattggc tttcactaag ccattttttt agttggaaag
    69181 tataaaaagg acttgtctct gctggaagat agtcttgaat acccgttgcc agattagaaa
    69241 ttacttgaac agcaaattta atgagccgcc aactagtttc ccctgttctg ccatagcggt
    69301 caaaacgcaa accagtatgt tctatttgat gttcggacaa catatcagcc cctgcaggcg
    69361 ttagctttgc ttcattttca tttatttcga tccaaccttg ctgcgcaatt ttttgcaaaa
    69421 tttgataaaa cttatcctgc ttcaattctg gaaaactgtt atggataaac aaaagttcgt
    69481 gggtaaatcc ataaataagt actgaagtcg ttcgttttcc cacaaggagt tggtaaagag
    69541 aactaatccg cagcttgtgt cctgatgaaa atagcgataa aataaaaaca atcatattat
    69601 tctccttaag ttaggatggt tagaaatgtc actactatgt aaacttgtac ctgaacgctg
    69661 tattgcatgc ggtctttgtc aaatcgaagc gccagatatt ttcgattatg atgaagaagg
    69721 aatcgtttta tttgcccaag aaccagaggc tcatcaacag ttcgtgatgc cggaagaaga
    69781 aacatatgta aaaaaagcgt atcaaaaatg tccagttcga gcgattttat tagaaaataa
    69841 aatataaata taaacgaaac tttaaaaacg tacactaagt tctctaaact tgaaaataag
    69901 ccgggatctg tttctcttgt tccgtgaaat cccgacttat tttgaaagat tcatttgcta
    69961 tctatagtta attgactagt tttttcacgg accctatagg acccatttat attatttcaa
    70021 ctttttcagc cagttttcca atgtattgac gatcacagtt tgctggtctg cgttagaaat
    70081 ttctgcctct ccatctcctt tttgctcacc atagctgcca aaacctccat gatttccgcc
    70141 attgattgat acatactctg ttctttccgg taaatactgc ttagcttctt gataagcttc
    70201 ctgattcaat actttatctt ttgtcgccgt gatcgataaa acaggaacag ctgattctgt
    70261 caatgttcct tttttgtcgg gataacttgc catgaagaat acccctttta aatgtttgtc
    70321 tgaatgattc ttattgacat aacgacttgc cattacgcca cctaatgaat ggccaccgat
    70381 cacataatcg gaatttggaa aatcttcttt gaccttatcc gctttgtttc cgcccatcac
    70441 tgctagatca agtggcattt tgacaatagc gactgaaaag ccgttttttg ctaaatcttg
    70501 cgcccaaata ctataacttt ctggctctac gagagcacca ggataaaaaa taagtaatgg
    70561 agactttcca tgattctttt tctctccttc aaaaaataag taatcttctt tgttttttcc
    70621 ttcttttacc aacacttgcg cttctgacga tggttcgtac gtattttgct gtatatagta
    70681 ataaccggct ccaccgagta atcctaaaat gatgactaag ccaattagta ttcgtctaaa
    70741 tattttcact ttctcccacc ttttctatct gagtgacccc tttttcttaa tcaagtatga
    70801 ttatacctta aaaaaataag agagaaatgc aaactttcca gcatcaaata aaaaaagacg
    70861 gaatatccat ttgaatatcc gccctttttg tatgtttatt tttatttagc acataaacga
    70921 tacacagctt ctgcataaat ttccattgct ttatacatac tacttaattc ccatcgttca
    70981 ttcgcctggt gcataaagtc aggagtatca gggaacatcg caccgaatgc cacacactgg
    71041 ttcatcgtac gagcaaaagt agcgccgcct gatacaaacg gttcagtcat gtctccagta
    71101 atatcgcgat atgtccccaa tagatttttc actaactcac tgtctagtgg cacgtataat
    71161 gaatcaagga agtcaaattc ttcataagtc aacccatatt tttctgctgt tttagttaat
    71221 ttagctacta aatcatcttt cttgaatgta acagggattc tcatatctac accgattttt
    71281 gtttgttctg gtgtgatttc caaacttgca aagttcatcg ttagctcgcc ggattgttca
    71341 tcttctgttt tgcccacgac agcttcacca gttgcatttt cttgaactaa ttttcctaag
    71401 aaattgattg ggccaaaatc aaatacttct gaaagagcaa ttgccagacg agaaatagca
    71461 ttcactcctt gtgctgcatc tttcgcgtgg atacttttac caagaacgac gatgccttca
    71521 ccttgttctt cgaaatcgaa ttcgtgtttt ttcaatgctt cttttacttc agaaagcttt
    71581 tctccagagt aaggagctgc atcaggaaca acattcaacg ctcctccagc ttttacagaa
    71641 aactcgttcg ttcctggtcc tgtcaagtaa gcttgcaata agcctttttc tgcataaatt
    71701 aaaggaaatt cagcatctgg cgcaaatcct tgcgtaattc cttcttcttt ttcgttatat
    71761 ttttctaaac aacgccataa attttcttca tctgtaccaa agataaaacg aatacgtgtc
    71821 ttgaattcca cgccagcatc aatcaaagct ttgacggcat acattgccgc aatagaagga
    71881 cctttgtcat cttgggatcc gcgaccaact aaccagccgt cttttatagt tggatcgaat
    71941 ggttttgttt cccaattatt ttcgtcccct gctggaacaa cgtccatatg acacaagata
    72001 ccgaataatt catctccaga gccaatctct gaataaccgt aatagccttc tggatcttta
    72061 aatgttctaa atcctagctt ttcactgatt tccaatactt tatccaaagc ttcaatcact
    72121 tttttaccga agggatgtcc ttgtcctgaa tctgcttcat ctagtacgga aggaattcgg
    72181 atcaattcgc tcaatgattc taatgcttgt tcatgatgtt gttctgtcac aaattttttc
    72241 atgatattat cctcctaata tgttaaaaag ggtcatgtca aattcctccg acacaacctc
    72301 ttcttctcaa ataatgacgt tttaagcctg ctccatcagc aagcagaatg ttcttaacaa
    72361 atgatgaaag aaaaaacact cactgaatgg agctattgac ttatccacgt gcttatcgat
    72421 agccgtttat cggtttcttc attcttatga tagaccttgt acctgtattt gtctaggttt
    72481 agaacattgc tgctacacct aggatcacac agatggctac aaataatatc gcaattaatt
    72541 taccggtaaa tttccaccac actgaaacat cgaaacgagc aattgctaca gcacccatta
    72601 cgatagcaga tgttggtgta attaagttta ctaaaccaga tgcagattga taagcagtga
    72661 ttactaaatc cttaccgacg ccggcaaatt cacccatagg tcccatgatt cccattgttg
    72721 cagcagctaa gccggaagtt gaaggaatca agaatgacat agggatatag aaaataaatg
    72781 taataatgat gaatacactt gaagataatg aacttaatcc ttgttcgccc caatgtaaga
    72841 tggtgtctgt gattaatcca ttgttcataa ccacttggat accacgagca acagctacta
    72901 cgattgctac accgatcaaa tcagaagcac cagctaaaaa ttcagagaca aattcagact
    72961 ctttcatgcc ataagtgatt gctactacga tggacattac taagaataac atagtaattt
    73021 ctgggaagta ccagtcacct aatggaagca tgcttttacc tagaaccgta cctagtaccg
    73081 gaaggtttgt taaccagttt gtcaatgatt caaaaatcgt gaaattcgca ttcaaggttg
    73141 tccaaggaat caaactgatg atcatgatac caaaagtaat aaagaacaat acattaacat
    73201 gtttttgttt tttcgtgatt acttcttgac gaccgattgc ttcaatatcg aaatgcttca
    73261 tatcttcttt acgttggttg tatactaatg attttgttgg atctttttcg atctttgatg
    73321 cataacgata cacatataca atagaaatag ctaacaaaat aacgaacatc aagaatcgaa
    73381 gaccaatacc ttcacccatc gaaatcccaa cagcttgtga agctacgcct gttgcaaaag
    73441 gatttaccgt tgaagctaga cagcctactt gagaccctac taatacgatt gctacagcta
    73501 ctactgtatc aaagcctaca gccatcatga ctgggatcag taaagcatag aatggaatcg
    73561 tttcttctgc cattccgtaa gtagagccgc ctaatgcaaa taacagcatc aatactggaa
    73621 taagcatttt ttcttttcct ttgaatttct tcacaactga agcaatcccg gcatctagtg
    73681 cccctgtttt gttgataata cctaaaaatc caccaacaac caaaatgaag aaagagattg
    73741 ggattgcagc aggtgtttct ttagttagct cccccgctgg tacacctagc atcccattga
    73801 ttggcgccat gaaaatatcc cacagccctt gaggattttg ttgtactcgt tcatatgatc
    73861 cagcgacgat gttgcctgca tcgtctacac tatagtgccc agctggtata aaccaagtaa
    73921 gtacagcgat tactgcaata ataataaata agaccgtata cgctgaaggc atttgaaatt
    73981 ttttcttttt tgtttgttcc atcttcttct tcctttcttt tccgttagag acaacaattt
    74041 tggctctaat gttattttat caaaaagagt atcagaacaa aaataataac acgcattttg
    74101 taaaactttt gttcaaaaag ttcgtttttc cctattccct cctctttttt caggttttta
    74161 aagctttctt ctttttcatt gtagcgtttc ctttttttta taaacaaaca ttttcgtctt
    74221 ttaaaaggag aagaatttca catttgcaaa gaattgattg atttttatgc ataaatcaaa
    74281 aaaatactca aaacaaacaa ataaaacgtt tacattattg catgtcttgt atttttttcc
    74341 aaaaaaaaag accaagaaat ttcttgatct ttttgatatt tatttgactg ctgtatgacg
    74401 ttgttcgaac tgatgttgtt ttcgacttaa ccatggaaga agttgcgcat gcagcactaa
    74461 aaagacagca ctcacgatga atcctttgat caagttgaaa ggaacgatcc caatcagtac
    74521 atagtttgct aaagacatgc ccagcatctg tgttgcgttc agccctaaaa acattaagta
    74581 aagaggcgta ataacgaaat aatttgcgat actcataaaa atagttagag cgatggttcc
    74641 tgtaatgaca cctaaaaatt tgtttcttcc tttatgctgt ttctttacac taaagaaata
    74701 ataaatcggg aatgtaaaga tcgttgttga taagaaacta gcagtgtctc ctaccaaatt
    74761 atccggagaa aaacctgtag tcagcagatg taatactgaa cgcaagaacg ctgttgcaac
    74821 tccggccgct ggaccgaata agaacatgct gatcaatacc gagatatcac taaaatcgat
    74881 cttcaaaaaa ctaaaagccg gcatgatcgg aaaagcaaaa tactgtaaaa ctaatgcgat
    74941 cgcagcaaac atcgctactg caaccatttt ctgtacacgg gtgttcttca tttgaaatcc
    75001 tcctgttagg actcctcttc agcgaacttt ttgacgtttc tctccaaatg aaaaaactct
    75061 attttccagg gaaaatagag ttagagttat ttgatcaagc gtcgtcaaat aagctctatc
    75121 ttctttatcc agactatact gtcggtatcg gaatttcacc gattcagcta tttttttgca
    75181 aaataggtcg tggactataa ccaccggtcg ggaatttcac cctgcccctg aagacgaacc
    75241 ttatataatt tttgtttaca tattcattat acatatctat tcaaaaaacg caacatctaa
    75301 cacttataaa aagtaagtgt tcattttgag tggttcagca aactgctgac ttcttttttg
    75361 ttcagttcac ggtaatcccc aggacgtagg ccttgtaaag tcagatctcc gtatttttca
    75421 cgttttagtt tttgcacagg aagaccaact gcttgaagca tatttttcac ttgatgatta
    75481 cgtccttcgt ggatcgtcaa ttccacgata ctgtggtttg tcttaggatc cactgataaa
    75541 atttggaatt tagctggaga tgtttttcgt ccttcgatct ttattccttt tgtcaaaggt
    75601 gcaagcatcg attttgtagc gatccctttt acctttgcaa cgtaaacttt atccacttca
    75661 tgttttggat gtgtcaggcg ctgagcaaaa tctccatcat ttgtcagtag caagatcccc
    75721 gaagtatcgt aatccagtcg acctacagga tagatacgtt cttttaccat cggcaaaaga
    75781 tccgtaacaa cttttcttcc tttgtcatct gcaacagcag aaataactcc tttaggtttg
    75841 tacaataaat agtaaccgta ttcttcttga taaattggga cttcatccac ttccacagtg
    75901 tcatgtttcc caacttttat ccctaattcc cttacaactt gtccgtttac ttttacacgt
    75961 cctgcaagga tgaattcttc tgcttttcga cgagaagtga tgccagcgtg ggcaattact
    76021 ttctgcaatc tctccattac aattattctc ctttattcat tccatcaaag aatagatctg
    76081 gtgacacgtc ttcttcaagt gaaatttcca tttcttgtgt atcaggcagt tcttctaatg
    76141 atttcaaacc aaaataatct aagaagtagc cagttgttcc atataatatc ggccgacctg
    76201 gtccttctac tctacctttt tcttcaatca gtttatgggc agctagacgc tgtaccgctc
    76261 ctgaaacctg aactcctcga atctgctcga tttcagctct tgtgattggc tgtttataag
    76321 cgatgattgc taaggtttcg acggcggctt gagataatgt gtttgatgtc ccttgcgcat
    76381 atcgcttaag taagggagcc agctcttttt tagtcgttaa tacataatgg ctttccgttt
    76441 caaaaatatg caaagctgag tgcgagtttt gagtgtaaga ttcttttaat tctttcacta
    76501 aacttgtgac ttctgcttcg ctgagattta acagtccgct taattcttca ttactgatcc
    76561 cttcctcgcc aacaataaaa agaagggctt caagttcact taatttcgtc atgttcggta
    76621 tctcctactg ctggataaag cataattgat tcatagtttt ctttttgttg cgcaatgatc
    76681 tgcccttttt tcatcaattc tagcaaagcc ataaaagtag tgacaacttc acttttagaa
    76741 ggtgactcaa aaaaagaatc gaaagtacag ccatgcgcat ttctttttat acgctcttcg
    76801 ataaatacca ttcgttcttc gatcgttgtg tcatcgggcg tgatcgtttt ttccactttt
    76861 tgagaaaatt tcttacgttc taagattttc tgcatggcac ggatcaaatc gatttttttg
    76921 acttgtcctc gcttcaacgg cttttcagca tccgctaacc catcgatgtt cataggttct
    76981 tttgtgtaat aaagacttcg ttcctctgct ttttctgtca gtctttcagc tgcatattta
    77041 tatttacggt attctaaaag ctgagtgacc aattcttctc gaggatcttc ttcccataat
    77101 tcttcatcgt ctgtgacgaa ttcttggaca ggaagcaatg tcttgctttt gattgccatc
    77161 aatgtagcag ccatcactaa gtattctcct gcaacagcta gctcgagtgt tttcattgta
    77221 tggatataat tcatatattg ctccgtgatc gtagcgatcg gtatatcata tatatcgatt
    77281 tccatttgct gaatcagatg aagcagcaga tcgagaggac cctcgaatac atctaattta
    77341 atattgatct ccgtcaactc attcactctt tcttcttttt ctttgctagc cattttccaa
    77401 tgtaaggctc tgtgatttca gttgcacgga tggagacatc cgggtacttt tcctgtaatt
    77461 catctaacat ttgaaagccc atattctcac cgcgataaga cggattcaaa gaaatgtcat
    77521 ggatgatcag ctgatcgttc gttgcccagt aaataccaat aatcccttga atgttggttg
    77581 aaccttctgg cgtaaagaaa aaaagttcat aatcgtcttc agattcgtac gtatcaatct
    77641 ccttcaacaa agaagtttta cctgtcagtt tcttatggaa actcaatagt cccatagcaa
    77701 ttttacggtt ttctttccgg taatgtgtta acatcttctc accttcctat gactaagccc
    77761 ttggaaaatg ctgcttataa acatccgtca ttcttttctt cgtgatatgt gtataaatct
    77821 gagtcgtaga gatatccgcg tgacctaaca attcctgtac tgtccgcaaa tcagctccat
    77881 tttctagcag atgtgtggca aagctatgcc gcagcgtatg tggtgttact tctttgtaaa
    77941 tcccagcctc tcgtactaac tgcttcagat ttttccagat tccttgccga gaaagacctt
    78001 tcccatgatt attgacaaat acatgcattt cagatgcgtc ctttacaagt aatggacgtg
    78061 cttcgtctaa gtagcgttcc agccattgga tcgcataatc acctaaagga atgatccgct
    78121 ctttatctcc ttttccaact gtctgtacca gtccaagaga aagatgaaga tctcccaatt
    78181 tcaatccaat caattcactg acgcgcatcc cagtagcata catgacttcc aagattgcac
    78241 gatctcttat ccctaacgtt tttgtcgtat caggtgcttc aatcagcttt tctacttctg
    78301 tcagagtcaa tgtacttggt aatttctgtg ctttcttcgg cgtatcgata tgttgcatcg
    78361 gatcatgatc agtgatacgc tcttgccgta aaaactgatg gaatcttctg agacttgaga
    78421 tcatccgagt aacagttgct gtcgcttttt tttcttcatg caacttctcc agaaaacgga
    78481 tgactaaaaa gcgatcgaca tcctgccatg aagcaatttt ctgctcctgt agaaaatgca
    78541 agtactgttc caaatcacgt tcatagcttt gtcgtgtatt ggcggacaat ccccgttcaa
    78601 tattcaagta gtggagataa tcgttgattt gctctttcat aataatcccc ctcatgcctc
    78661 tctatcatat cagataccgc ttcattctga tagtcttttt ccataatctg agcaaag
//
LOCUS       DASHXG010000007        78084 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.007, whole genome shotgun sequence.
ACCESSION   DASHXG010000007 DASHXG010000000
VERSION     DASHXG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.007"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="U2R59_000575"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="U2R59_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HEM8964997.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2945..3379)
                     /locus_tag="U2R59_000576"
     CDS             complement(2945..3379)
                     /locus_tag="U2R59_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8964998.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3396..4601)
                     /locus_tag="U2R59_000577"
     CDS             complement(3396..4601)
                     /locus_tag="U2R59_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEM8964999.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5295..5681
                     /locus_tag="U2R59_000578"
     CDS             5295..5681
                     /locus_tag="U2R59_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8965000.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5775..5965
                     /locus_tag="U2R59_000579"
                     /pseudo
     CDS             5775..5965
                     /locus_tag="U2R59_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            6479..6811
                     /locus_tag="U2R59_000580"
     CDS             6479..6811
                     /locus_tag="U2R59_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8965001.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="U2R59_000581"
     CDS             7107..7262
                     /locus_tag="U2R59_000581"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HEM8965002.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="U2R59_000582"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="U2R59_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="U2R59_000583"
     CDS             complement(9119..10735)
                     /locus_tag="U2R59_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEM8965003.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="U2R59_000584"
     CDS             10853..11071
                     /locus_tag="U2R59_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965004.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="U2R59_000585"
     CDS             11266..11727
                     /locus_tag="U2R59_000585"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8965005.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="U2R59_000586"
     CDS             complement(11920..12159)
                     /locus_tag="U2R59_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965006.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="U2R59_000587"
     CDS             complement(12183..13706)
                     /locus_tag="U2R59_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEM8965007.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="U2R59_000588"
     CDS             complement(13724..13846)
                     /locus_tag="U2R59_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEM8965008.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="U2R59_000589"
     CDS             complement(13876..14859)
                     /locus_tag="U2R59_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HEM8965009.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="U2R59_000590"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="U2R59_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8965010.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="U2R59_000591"
     CDS             complement(15053..15430)
                     /locus_tag="U2R59_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965011.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="U2R59_000592"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="U2R59_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEM8965012.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="U2R59_000593"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="U2R59_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEM8965013.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="U2R59_000594"
     CDS             complement(16448..18214)
                     /locus_tag="U2R59_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965014.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="U2R59_000595"
     CDS             complement(18174..19928)
                     /locus_tag="U2R59_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965015.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="U2R59_000596"
     CDS             complement(20038..20607)
                     /locus_tag="U2R59_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEM8965016.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..22040)
                     /locus_tag="U2R59_000597"
     CDS             complement(20625..22040)
                     /locus_tag="U2R59_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8965017.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22051..22719)
                     /locus_tag="U2R59_000598"
     CDS             complement(22051..22719)
                     /locus_tag="U2R59_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEM8965018.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22849..23433)
                     /locus_tag="U2R59_000599"
     CDS             complement(22849..23433)
                     /locus_tag="U2R59_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965019.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23764..23997)
                     /locus_tag="U2R59_000600"
     CDS             complement(23764..23997)
                     /locus_tag="U2R59_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HEM8965020.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24012..24962)
                     /locus_tag="U2R59_000601"
     CDS             complement(24012..24962)
                     /locus_tag="U2R59_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEM8965021.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24959..25801)
                     /locus_tag="U2R59_000602"
     CDS             complement(24959..25801)
                     /locus_tag="U2R59_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8965022.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25803..26522)
                     /locus_tag="U2R59_000603"
     CDS             complement(25803..26522)
                     /locus_tag="U2R59_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8965023.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27214..27372
                     /locus_tag="U2R59_000604"
     CDS             27214..27372
                     /locus_tag="U2R59_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965024.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27444..28670
                     /locus_tag="U2R59_000605"
     CDS             27444..28670
                     /locus_tag="U2R59_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8965025.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="U2R59_000606"
     CDS             complement(28758..29150)
                     /gene="rpsI"
                     /locus_tag="U2R59_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEM8965026.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29166..29609)
                     /gene="rplM"
                     /locus_tag="U2R59_000607"
     CDS             complement(29166..29609)
                     /gene="rplM"
                     /locus_tag="U2R59_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEM8965027.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30128..30595)
                     /locus_tag="U2R59_000608"
     CDS             complement(30128..30595)
                     /locus_tag="U2R59_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEM8965028.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30715..32253)
                     /locus_tag="U2R59_000609"
     CDS             complement(30715..32253)
                     /locus_tag="U2R59_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HEM8965029.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32333..33019
                     /locus_tag="U2R59_000610"
     CDS             32333..33019
                     /locus_tag="U2R59_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEM8965030.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="U2R59_000611"
     CDS             complement(33220..33747)
                     /gene="msrA"
                     /locus_tag="U2R59_000611"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEM8965031.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="U2R59_000612"
     CDS             complement(33831..34508)
                     /gene="pgmB"
                     /locus_tag="U2R59_000612"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEM8965032.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34505..35635)
                     /locus_tag="U2R59_000613"
     CDS             complement(34505..35635)
                     /locus_tag="U2R59_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8965033.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35635..37818)
                     /locus_tag="U2R59_000614"
     CDS             complement(35635..37818)
                     /locus_tag="U2R59_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEM8965034.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37815..38840)
                     /locus_tag="U2R59_000615"
     CDS             complement(37815..38840)
                     /locus_tag="U2R59_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8965035.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38885..39712)
                     /locus_tag="U2R59_000616"
     CDS             complement(38885..39712)
                     /locus_tag="U2R59_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEM8965036.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39709..40776)
                     /locus_tag="U2R59_000617"
     CDS             complement(39709..40776)
                     /locus_tag="U2R59_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HEM8965037.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40802..41638)
                     /locus_tag="U2R59_000618"
     CDS             complement(40802..41638)
                     /locus_tag="U2R59_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965038.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41635..42504)
                     /locus_tag="U2R59_000619"
     CDS             complement(41635..42504)
                     /locus_tag="U2R59_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965039.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42574..43857)
                     /locus_tag="U2R59_000620"
     CDS             complement(42574..43857)
                     /locus_tag="U2R59_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEM8965040.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43871..45556)
                     /locus_tag="U2R59_000621"
     CDS             complement(43871..45556)
                     /locus_tag="U2R59_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HEM8965041.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45831..46856
                     /locus_tag="U2R59_000622"
     CDS             45831..46856
                     /locus_tag="U2R59_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965042.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47451..51125)
                     /gene="rpoC"
                     /locus_tag="U2R59_000623"
     CDS             complement(47451..51125)
                     /gene="rpoC"
                     /locus_tag="U2R59_000623"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEM8965043.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(51183..54800)
                     /gene="rpoB"
                     /locus_tag="U2R59_000624"
     CDS             complement(51183..54800)
                     /gene="rpoB"
                     /locus_tag="U2R59_000624"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEM8965044.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55528..56496
                     /locus_tag="U2R59_000625"
     CDS             55528..56496
                     /locus_tag="U2R59_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965045.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56514..57419
                     /locus_tag="U2R59_000626"
     CDS             56514..57419
                     /locus_tag="U2R59_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965046.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57416..58222
                     /locus_tag="U2R59_000627"
     CDS             57416..58222
                     /locus_tag="U2R59_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965047.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58358..59347
                     /locus_tag="U2R59_000628"
     CDS             58358..59347
                     /locus_tag="U2R59_000628"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HEM8965048.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59664..60188)
                     /locus_tag="U2R59_000629"
     CDS             complement(59664..60188)
                     /locus_tag="U2R59_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HEM8965049.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60475..62115
                     /gene="scm"
                     /locus_tag="U2R59_000630"
     CDS             60475..62115
                     /gene="scm"
                     /locus_tag="U2R59_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HEM8965050.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTS
                     STTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSK
                     RALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(62270..63256)
                     /locus_tag="U2R59_000631"
     CDS             complement(62270..63256)
                     /locus_tag="U2R59_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEM8965051.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(63279..63845)
                     /locus_tag="U2R59_000632"
     CDS             complement(63279..63845)
                     /locus_tag="U2R59_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HEM8965052.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(63859..64275)
                     /locus_tag="U2R59_000633"
     CDS             complement(63859..64275)
                     /locus_tag="U2R59_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HEM8965053.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(64732..66666)
                     /locus_tag="U2R59_000634"
     CDS             complement(64732..66666)
                     /locus_tag="U2R59_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8965054.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGKSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            66947..67903
                     /locus_tag="U2R59_000635"
     CDS             66947..67903
                     /locus_tag="U2R59_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HEM8965055.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            67993..69096
                     /locus_tag="U2R59_000636"
     CDS             67993..69096
                     /locus_tag="U2R59_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEM8965056.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            69109..70062
                     /gene="menA"
                     /locus_tag="U2R59_000637"
     CDS             69109..70062
                     /gene="menA"
                     /locus_tag="U2R59_000637"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HEM8965057.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(70876..72222)
                     /gene="gor"
                     /locus_tag="U2R59_000638"
     CDS             complement(70876..72222)
                     /gene="gor"
                     /locus_tag="U2R59_000638"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEM8965058.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(72356..73609)
                     /locus_tag="U2R59_000639"
     CDS             complement(72356..73609)
                     /locus_tag="U2R59_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEM8965059.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(73615..74538)
                     /locus_tag="U2R59_000640"
     CDS             complement(73615..74538)
                     /locus_tag="U2R59_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEM8965060.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(74759..77251)
                     /locus_tag="U2R59_000641"
     CDS             complement(74759..77251)
                     /locus_tag="U2R59_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEM8965061.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(77258..77725)
                     /locus_tag="U2R59_000642"
     CDS             complement(77258..77725)
                     /locus_tag="U2R59_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEM8965062.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(77861..77934)
                     /locus_tag="U2R59_000643"
     tRNA            complement(77861..77934)
                     /locus_tag="U2R59_000643"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(77898..77900),aa:Arg,seq:acg)
     gene            complement(77992..78065)
                     /locus_tag="U2R59_000644"
     tRNA            complement(77992..78065)
                     /locus_tag="U2R59_000644"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78029..78031),aa:Pro,seq:tgg)
BASE COUNT        23561 a        15823 c        13240 g        25460 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa aagtacattt cttcatgttt ttttcggata tttgtgcttt ttaaccattc
     2521 agcagctgaa aacatataaa aagatatgta tgtattcttt ctgaaattaa gttcatttct
     2581 atgcgatgaa gcatgttttc aaaatattac cctttcttag attaaacttc agagtattca
     2641 aataacggaa taaggagcct tatcccgcat tactgaatga gactgtgaca taagtaaaaa
     2701 ggtgacttca aattccttct tcggaatttg aaatcacctt ctttataatt ataaagtatc
     2761 ggtttcacag catttctgaa tgattcctag aatcttaaac gaatgattgg agttatcaac
     2821 attttttcac tcgtttttag cgaaacaaaa aatgacattt gtcacagcct cattaaatta
     2881 ttgattcttt ttctttataa ttgaattgtc catatttaaa gtgtctagta ctctacatga
     2941 ataattaatt gctttcactc aaatacttat aatctattaa cttgtagttg tttaactttt
     3001 ctgaaaaagt tagacccacg taataatctt cccagctttc tctttcaatt aactgatcca
     3061 atttttgata atccataaat tcatcatgta tcaaaaagaa taaataactt gatattttag
     3121 catctagctt aatcagatta aataatgttt gtttaaaatt gctaccatta atatgactga
     3181 tagattctct agcttcttca cataaacttt ttactttatt aattactact ttgtcatatt
     3241 catttaacac actattatta ccattactta gacgctcaga ttctacgaaa caactcaaat
     3301 cagaaatttc ccaaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3361 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattgtcc
     3421 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3481 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3541 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3601 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3661 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3721 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3781 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3841 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3901 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     3961 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     4021 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4081 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagattttct
     4141 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4201 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4261 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4321 aaaactttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4381 atgtatagaa gaaacatctc attaaaatca ccagtaaaga aatggaaatc tttagttttt
     4441 ttaatattat cagttagtaa ctttttataa tcataaaaaa aataagtagt tctatctgag
     4501 cgatactctt ttataatact gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa
     4561 acatgaagag actttaataa gacttcttta tctgaaaaca cttttgtttc tctctttcct
     4621 ttctacatca ttaaatagta ttttatacgt tatctaaaat actattcctc tgtcaaaata
     4681 agctaactta cttcattata aaatatccac ttatcgcttt catgtatatt ccaccgtaaa
     4741 aagtacattt tatcaccgag aactcatcat ttttcatcat gatgaatact atttacatat
     4801 atctagttca aagacaataa ttattatgat ccgttattat ctaagcacta tacagataat
     4861 aggaattttt cgtttctaaa tattccaatt tgggaatcca ataaaaattt tcgttcaaat
     4921 acgtgtctat tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata
     4981 caatctatac acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac
     5041 gtaaaaagct caagacattt tcttagccat aaggacatgt ttgatattta agaagatata
     5101 tgaattttct tttctaagta taaagataac tatccattat caactaaaaa aacatttttg
     5161 aaaataaaca tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca
     5221 gcataattgc attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg
     5281 aggaggtgtg caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct
     5341 ttgaaaaggt cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa
     5401 aacatgaaca acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta
     5461 aacaaccgat taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa
     5521 tccttccttt gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttgata
     5581 aaactgataa agaaattgga aaggttctgg ggattacaag acagggtgcg acaaatttaa
     5641 aacatcgact ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat
     5701 tttgtatgct tctttgctcg ttctcctcct tcccaaagaa atagattata agtccatggg
     5761 aagaaggtag atttatgaat tctttaaaag aagatttcat tttagcaaag gctggaaatg
     5821 aagaagctgt tgaggcaatt ctcaaaagat ttagctcttt gattcataag caatcctgag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt cttttatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21361 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21421 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21481 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21541 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21601 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21661 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21721 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21781 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21841 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21901 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    21961 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22021 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22081 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22141 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22201 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22261 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22321 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22381 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22441 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22501 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22561 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22621 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22681 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22741 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22801 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22861 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22921 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    22981 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23041 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23101 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23161 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23221 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23281 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23341 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23401 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23461 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23521 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23581 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23641 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23701 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23761 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23821 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23881 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    23941 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24001 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24061 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24121 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24181 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24241 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24301 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24361 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24421 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24481 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24541 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24601 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24661 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24721 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24781 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24841 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24901 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    24961 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25021 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25081 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25141 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25201 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25261 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25321 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25381 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25441 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25501 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25561 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25621 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25681 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25741 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25801 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25861 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25921 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    25981 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26041 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26101 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26161 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26221 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26281 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26341 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26401 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26461 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26521 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26581 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26641 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26701 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26761 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26821 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26881 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    26941 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27001 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27061 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27121 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27181 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27241 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27301 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacattt
    27361 aaaataactt gaaattttct tctcgccgca tatactaaaa ttagtgaaat atactgcctt
    27421 acttttttta aggagtgagg attttgccta caaagctttc aaatgggaaa tataaaacta
    27481 atctgagata tccaaaaagg tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa
    27541 aaacatttcc aaataggcaa ttggcgatta aagccgaaaa tgatatgaag aagaaaatag
    27601 aaaaagtttt gagagaggag aatgcaaact cattagaatt aaaaggaaaa ataacgttta
    27661 aaaaatttta cgaatctaaa tggcttccta gatatgaatt aggtcaaaca attagatcaa
    27721 acaggcctcc tagtgatata accattagta atacaaaaga tatatttcgg ttgcatattt
    27781 tacctatgtt tggtgaatac gcaatgaatt atctaaatat caatactgag ataatatcag
    27841 atgaattaac caaaaaatcg aaagaatatg caaatataaa aatcataaaa ggatatgttc
    27901 gttccatgtt cgatattgca gaaatactaa attatatcga atttaatcga actactaaaa
    27961 ttattcaaag tatcactgca cctaaaaaaa atgctttaga agaaaaaaga atacaagaag
    28021 gtaagcaagc actatcatca aaagaactta ctaattggat agaagcagta aatgatgatt
    28081 ttaataatca tttacttact tttcatgatt acacactttt tatgattacc ctgtatcttg
    28141 gtgatagaaa aagtgagact tacgctttgc aatggaaata tattgatttt gaaaaacaaa
    28201 cggtccgtct taaacatact ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa
    28261 aagataccgt cattcaagta ccagaagttg taatgacatt gctaagtgaa tggaaatcgg
    28321 tacaagctga tcaattgttg aaattaaaaa ttaagcaaac gttagatcag tatctcttta
    28381 cttatactaa accatctgga gaagtaaatt gtcctgttca tgccgattac ctaaactatc
    28441 gaatcaattc aattaaaaga aggcatcctg acttagttca tttatctcca cacaaactcc
    28501 gtcatactta tgcaactata gctagacaag gtggagcaga tatgaatcaa atttcaaatg
    28561 ctttaacaca ctcagatatt tctacaacaa agatatatgt gaacacacca gatatagttg
    28621 ataaggctgt ttttgaagct tttcagagag gattgaataa gtgtgattga tatgtgttct
    28681 taaatgtgtt cttaaaaaca aaagaagcac tttccaaata attgaaaagt gccagaaacg
    28741 ttgatatata aaggatatta acgttttgag aattgtgaag ctttacgtgc tttcttaaga
    28801 cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc acgtttaaga
    28861 gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg acggatagct
    28921 cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata tgcgcctttt
    28981 gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg tggaatgtat
    29041 tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag acgtacgcga
    29101 gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa tgaaattccc
    29161 tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc atgtggatgt
    29221 tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt gtttttagga
    29281 agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg caattcgcca
    29341 gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc
    29401 gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa atcgccagta
    29461 tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc aacaactgtt
    29521 gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg ttctacttcg
    29581 cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag ttctgatgtt
    29641 tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat ttaacatatt
    29701 acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt atatgaaact
    29761 ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa
    29821 gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg ttctcctgcc
    29881 aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt ttaaaattgt
    29941 ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg tgttcaatca
    30001 gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt tgacgtttgt
    30061 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc aagttcaaca
    30121 acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc atccagatac
    30181 gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg tcgccttctt
    30241 ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag cctgcaacaa
    30301 gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca gggatttttg
    30361 tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt
    30421 cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc attgggtgca
    30481 atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca acagacattt
    30541 ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat ttcatctttc
    30601 ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga aaagtacaac
    30661 aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag ccaatcattt
    30721 ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct gtgctaaatg
    30781 cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat cagtttcttg
    30841 tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac tttggatctt
    30901 tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg tgacagtagg
    30961 gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg gagattgagc
    31021 aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc cttttaaaat
    31081 ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt tttctgtatg
    31141 ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc
    31201 accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa aagcgatagc
    31261 cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa cgacttcctg
    31321 taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg ctcctcccac
    31381 tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat ggaactgagg
    31441 ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc
    31501 accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca aaacaaatga
    31561 tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg ttacttgata
    31621 ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt caagcacttc
    31681 ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg ttccgtagtc
    31741 gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga caaaataagc
    31801 agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt tcaatggtgt
    31861 cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca cggtatattt
    31921 cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc gagataacgg
    31981 tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg agacaaattg
    32041 aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc agacaccttg
    32101 aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca aagggtagcg
    32161 aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt
    32221 ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt tatgtatgta
    32281 caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg gcgtgttact
    32341 ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc agcggattcc
    32401 gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc gttcgctttc
    32461 ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct gccgctattg
    32521 caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg gtctttttgc
    32581 ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc
    32641 tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca cgctattctg
    32701 ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt
    32761 gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc
    32821 tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag agttgcttca
    32881 gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact ttatctgtca
    32941 taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt tgctgattgt
    33001 ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac ctctgatata
    33061 tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca caacctctcc
    33121 actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg ttttacaacc
    33181 tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga cgccccaatg
    33241 tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat ggagcttgtt
    33301 tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc ttggttcgat
    33361 ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc
    33421 tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag aatcaccgcg
    33481 atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga tttccaccaa
    33541 ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg tatgccctgt
    33601 tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag tataaccgga
    33661 tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc aaaagcatcc
    33721 gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat cataccttga
    33781 tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta ttatatacgt
    33841 gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt taaatcagga
    33901 atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac atgcatgtta
    33961 ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca tgcatttggc
    34021 ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt tgcttttgat
    34081 acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt ttctaaaatg
    34141 aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt tttcaagtac
    34201 tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg aatcgcttga
    34261 agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga gaatttctgt
    34321 tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat tcctttcagt
    34381 tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac cagccacgct
    34441 tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag tgctgctttg
    34501 attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg atgtttttag
    34561 ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag
    34621 gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt cctttaccaa
    34681 cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca atcccaactg
    34741 gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt acgaggtctg
    34801 cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg ccagagacta
    34861 ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca ctactgcccg
    34921 atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct tggtcagcca
    34981 ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa gcgccttctt
    35041 ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta atcagctcaa
    35101 taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc agtgcttcta
    35161 ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg ccgatgccgc
    35221 catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca
    35281 attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt tgttggttta
    35341 gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg
    35401 aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct gtttgccgct
    35461 tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg cctataggta
    35521 gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg
    35581 cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata cgcattattt
    35641 tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat tgacaaaaat
    35701 aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca aaacaaatag
    35761 caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg aaggaagtct
    35821 tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa atataactgc
    35881 tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat gcggatctgg
    35941 tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca tttcttggat
    36001 acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt
    36061 ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag gtaataagta
    36121 taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt cgctacgggc
    36181 ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca aatcaataac
    36241 tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag gcactggcaa
    36301 atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc cagcttgata
    36361 tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat tattgtcgat
    36421 atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat catcgacttt
    36481 tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc cctttgtttc
    36541 taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag caaggtctgc
    36601 actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg ttttgatatt
    36661 caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc atgggaaaag
    36721 tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg
    36781 gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag gcaggataaa
    36841 aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc ccttcgcccc
    36901 tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag cagcgaagtc
    36961 catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa
    37021 atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc ttttctgggc
    37081 ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga gcacgatgat
    37141 cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag cggtgatccg
    37201 gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc caatatcaat
    37261 tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata ctcgcagttc
    37321 tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac ccgttttcac
    37381 atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg cctgatggag
    37441 attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt gagcagtttc
    37501 aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct cgtatgcaag
    37561 aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc atctgatgac
    37621 atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat atacaccagc
    37681 tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc tgataccaaa
    37741 aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta aatcaaactg
    37801 tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg atataaattt
    37861 tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg agtctggtca
    37921 ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt aactggcgtg
    37981 gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc tggatacaga
    38041 ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct gatattcaaa
    38101 gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt gccaaaaatt
    38161 gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga attttttttc
    38221 gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa tccagtaata
    38281 tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc tccttgaagt
    38341 tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc attcgcttct
    38401 acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc ttcgtcagaa
    38461 aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt ctctgccatc
    38521 tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga agcattagct
    38581 tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac actcacgata
    38641 tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga aaatcctgta
    38701 cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc caattctaag
    38761 acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg tccagcgcct
    38821 atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta ttgttattct
    38881 ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag tttttcaagt
    38941 attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga cattcatata
    39001 ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta aaatcaattg
    39061 cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc acatactctt
    39121 tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga taaaaatcag
    39181 cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca tccgctaaca
    39241 aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc gtacctgttt
    39301 cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag tctccttctt
    39361 tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa gctgctggga
    39421 taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca atttgacgta
    39481 caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag ccgttacaag
    39541 ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg atattttcta
    39601 ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata aatctaaatt
    39661 tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc attgttctcc
    39721 tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta cataacgcat
    39781 gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt cacaatccaa
    39841 gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt tccatcttgg
    39901 gtaatctggg tttggttcac tagatgctcg agcaaagacg atttttgcat tattgaaatg
    39961 tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa cataagaaat
    40021 gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac tgccactcgt
    40081 ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa aaccgacatc
    40141 tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt ctctacgctg
    40201 cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta attgaatcgc
    40261 aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc gaacatgtgc
    40321 ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat ttttccattg
    40381 atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa tcagcgtttc
    40441 acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca ccaaactgcc
    40501 cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa ataccacacc
    40561 gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa attcttcatc
    40621 gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg gagtagcgaa
    40681 aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc
    40741 ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct ttcttttctt
    40801 tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca gataacgcat
    40861 acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt ccccaaatgt
    40921 agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg
    40981 acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa taaacgaaga
    41041 cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc tggatccggc
    41101 taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt
    41161 ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc agtgctgtat
    41221 tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg atcaaaatac
    41281 cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct ttgaagcgta
    41341 gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg gaggctatca
    41401 aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa
    41461 tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc gttgcaattg
    41521 cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac aaattgacag
    41581 ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta tttttcattt
    41641 caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga acaatagaat
    41701 cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat acaaataaac
    41761 gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat agaacatcca
    41821 gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca gtgtcacgat
    41881 cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa gcgttttgtc
    41941 gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc tccagatagc
    42001 aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg gtgcttcgtt
    42061 gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat tattgaacat
    42121 atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata aaatcagtga
    42181 acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa
    42241 agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta aagaacgata
    42301 aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa cggcgtctga
    42361 gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca ttggaatcag
    42421 cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta attttaagtc
    42481 agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca atagctatct
    42541 acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt gtgcgtcagc
    42601 taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt ttccgatcac
    42661 acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta gtccaaagac
    42721 ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag acttgatgac
    42781 ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt gagcaccacc
    42841 aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag ctgtgaatgc
    42901 ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc cagatactgt
    42961 gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc
    43021 cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg ctgttccatt
    43081 catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt attgggataa
    43141 gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta cctcgccttc
    43201 atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt gctcactcat
    43261 tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat ctgtgaaatg
    43321 ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag cttctgataa
    43381 tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag caatatagct
    43441 ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat cttctccagc
    43501 ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat ccatcacttt
    43561 agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag ctaacgtaac
    43621 gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga tgtctggatt
    43681 ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct gttcgacaga
    43741 agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac tttcaccaca
    43801 agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt ttttcatttt
    43861 tttccacctc ttattttatt attttcagcc acatatattc atacggctgg aatatcaact
    43921 ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa tctccttttg
    43981 gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact ttctcttcct
    44041 tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa atcaaactat
    44101 tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat tcaccatata
    44161 ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac aaaaattttt
    44221 gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca tttcgacttc
    44281 ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa aatgaatgag
    44341 cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt aacgcatcta
    44401 gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc ttgtagttta
    44461 ctcgggcacc ctctttcttc agctgttcca ctaattcaag gatcgttttt tccggcagaa
    44521 tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta aaaaaagttg
    44581 tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt gtattacccg
    44641 aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc tgtgcttcat
    44701 tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc tcagtgatca
    44761 ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg attttatgcg
    44821 tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc acagcgtcca
    44881 agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc attttcaata
    44941 aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt
    45001 gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag
    45061 tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg tacgtatcat
    45121 tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg cagacaaagt
    45181 cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg cccaaacggt
    45241 cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat gggaaaaatg
    45301 gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat ttcttaaatg
    45361 tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc aagaaaatat
    45421 cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa acactgactt
    45481 tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa atcgcttgta
    45541 aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa cgatttgatc
    45601 atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga tatacacaaa
    45661 aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa atatggtctc
    45721 tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag aatgtctatt
    45781 gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa ttgaaaccta
    45841 ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc agagtattaa
    45901 ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca atcaaagaat
    45961 tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt gacgcgattc
    46021 tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt tcagatgtta
    46081 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    46141 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    46201 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    46261 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    46321 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    46381 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    46441 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    46501 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    46561 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    46621 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    46681 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    46741 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    46801 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    46861 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    46921 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    46981 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    47041 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    47101 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    47161 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    47221 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    47281 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    47341 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagacaaac
    47401 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
    47461 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
    47521 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
    47581 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
    47641 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
    47701 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
    47761 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
    47821 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
    47881 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
    47941 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
    48001 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
    48061 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
    48121 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
    48181 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
    48241 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
    48301 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
    48361 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
    48421 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
    48481 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
    48541 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
    48601 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
    48661 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
    48721 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
    48781 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
    48841 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
    48901 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
    48961 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
    49021 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
    49081 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
    49141 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
    49201 tcttttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
    49261 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
    49321 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
    49381 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
    49441 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
    49501 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
    49561 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
    49621 atatcttgag aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
    49681 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
    49741 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
    49801 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
    49861 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
    49921 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
    49981 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
    50041 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
    50101 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
    50161 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
    50221 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
    50281 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
    50341 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
    50401 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
    50461 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
    50521 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
    50581 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
    50641 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
    50701 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
    50761 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
    50821 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
    50881 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
    50941 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
    51001 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
    51061 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
    51121 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
    51181 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
    51241 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
    51301 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
    51361 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
    51421 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
    51481 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
    51541 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
    51601 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
    51661 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
    51721 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
    51781 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
    51841 actggtgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
    51901 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
    51961 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
    52021 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
    52081 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
    52141 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
    52201 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
    52261 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
    52321 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
    52381 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
    52441 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
    52501 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
    52561 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
    52621 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
    52681 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
    52741 tcaacgacac catcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
    52801 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
    52861 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
    52921 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
    52981 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
    53041 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
    53101 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
    53161 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
    53221 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
    53281 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt
    53341 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
    53401 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
    53461 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
    53521 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
    53581 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
    53641 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
    53701 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
    53761 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
    53821 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
    53881 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
    53941 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
    54001 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
    54061 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
    54121 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
    54181 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
    54241 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
    54301 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
    54361 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
    54421 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
    54481 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
    54541 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
    54601 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
    54661 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
    54721 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
    54781 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
    54841 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
    54901 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
    54961 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
    55021 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
    55081 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
    55141 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
    55201 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
    55261 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
    55321 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
    55381 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
    55441 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
    55501 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
    55561 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
    55621 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
    55681 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
    55741 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
    55801 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
    55861 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
    55921 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
    55981 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
    56041 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
    56101 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
    56161 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
    56221 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
    56281 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
    56341 ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
    56401 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
    56461 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
    56521 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
    56581 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
    56641 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
    56701 cttgtcttct aggcttttta gggagtgcgg cagcagggct tgtttccgga ctgcttcaca
    56761 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
    56821 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
    56881 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
    56941 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
    57001 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
    57061 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
    57121 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
    57181 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
    57241 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
    57301 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
    57361 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    57421 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    57481 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    57541 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    57601 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    57661 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    57721 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    57781 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    57841 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    57901 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    57961 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    58021 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    58081 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    58141 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    58201 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    58261 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    58321 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    58381 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    58441 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    58501 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    58561 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    58621 acaaacgatg atgacttctg aatctacgat gaaagatgcc aaactggcag cagctcaagg
    58681 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    58741 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    58801 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    58861 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    58921 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    58981 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    59041 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    59101 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    59161 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    59221 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    59281 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    59341 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    59401 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    59461 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    59521 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    59581 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    59641 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    59701 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    59761 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    59821 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    59881 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    59941 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    60001 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    60061 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    60121 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    60181 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    60241 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    60301 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    60361 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    60421 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    60481 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    60541 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    60601 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    60661 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    60721 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    60781 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    60841 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    60901 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    60961 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    61021 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    61081 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    61141 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    61201 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    61261 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    61321 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    61381 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    61441 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    61501 acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat
    61561 actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact
    61621 acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc
    61681 tctaccacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga tactacctct
    61741 accacaagtg atagctcaga ttcatctacc actacaagtg atagcacgga cacgtcagct
    61801 tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc atcaacttca
    61861 agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag tgtctccttc
    61921 tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac aagcaatgac
    61981 aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa taattggata
    62041 acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat gagttataag
    62101 aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta acggacgttg
    62161 ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg tcaaaaaaca
    62221 cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt cagtctttgc
    62281 gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga gaggtggcag
    62341 gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt
    62401 cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct tcttctgtca
    62461 ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc aaagagtaga
    62521 tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg ccgatttcct
    62581 ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc ccgatagaaa
    62641 gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca aaagcgccaa
    62701 cagaacaact taattggaac agttcagctg tcttacctga aatattttcc aaatattctt
    62761 ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca ttcaatactt
    62821 tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa tcagacaata
    62881 gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca ttaccaaact
    62941 gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata tcatcatgga
    63001 tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct ttgtctcgat
    63061 cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac agctttccgc
    63121 cggcatggat cgtttctttg attgcttgtt cgacaggttt gtttttcagg cggacagttt
    63181 cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag ttttcccaca
    63241 ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt aaacattggg
    63301 ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag tgtctgcaca
    63361 tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat ccctaaaact
    63421 gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga agccatcaaa
    63481 agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat actgacacgt
    63541 tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc accactcata
    63601 ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag tcgtagccaa
    63661 agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt gattagattg
    63721 gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcat attttccaat
    63781 aaaccaatga tcactccttg tgcaacaagt agcgaaatat aaatcatttt ttgtaattta
    63841 ctcatggtgt gtaaaggtct aataaatcag actgtcttcg tcacctccat ctgttgaacg
    63901 gacttcgatc actaatttat gtggcaaaca gacgatggtt tcgccatttt tcgttgccca
    63961 gcctcgacgt acgcagatct ggtcatcgca atctgcttct tttatccgta ctcgatcgcc
    64021 atctatctcg atcaagttat aatctccgtg ttcatctttg taagtatatg tgttgctctc
    64081 ttctccagcc atcaaaggga atgttttgat ttctgtgcca tccacacgca gtaccgcttc
    64141 tttttctgct gttgcggtgt tttgctgaag accaaaaatc atgactggta aaaaagaaag
    64201 aacagtcaaa agcaaaataa taaaaacatc ccaaggtttg agcagacttt tttcagcaaa
    64261 ttctttaagg ctcatttttg ttctcctttt tccagattaa ctcacccaat tttagcataa
    64321 aaacaagagg ttgtgacacc tgtgtcttgc tttgagtaat aagaacgaag aatagaaaac
    64381 agctttccat gttttctaat tctttgggct tattaccgag aagcagcagg tggaacaccg
    64441 tttataacaa gaggttgtga cagaagtggg caacttcaag aaataagaag gaatttacga
    64501 aaattacttt tcaagttttt gtgaaatttc ggcttatttt tcgaagaagc tacttctgga
    64561 acaccgttta taacaagagg ttgtaacaga ggttgtgaca cctgtgtctt gctcatggag
    64621 gcttatctcg ggcatcttat tcctttaatt ttacataaaa aggaggctgt gacggtttgt
    64681 ctcagcccct ttctattgaa atcttgcatt caaataacgt tctttatcta tttatttctt
    64741 gccgtactgg gaacttggtc taccgtacca ccaattacct agtgtacgtt gtagccatgg
    64801 aattacccag cgatccaacc caatcgcacg tccggaaccg ttcatcaatg cgaaagcaac
    64861 aaaaatgaac caaatgttta cccagtaaaa catgcctgat aagcagaacg tgatcaccaa
    64921 tacaatcgtt gtcgcactgc atagccatgt gaataatcca gcaatcaatg ctaatgccaa
    64981 ggcaatttca aagaatacca tgaatttttg gaagaacatt gctacatcat tgtttggcat
    65041 gatcacttgc atgatctttg tgaaccagtc tggtgacttc tcaatcacag ccattggttc
    65101 ttcaccgtat gcataactca aaccaaaatg tgcagcttga gtcgctgctt ctccggcact
    65161 tgcccctgct ccgctggcag ctgtggttgc atcaccagca gcagaagcac cactggcaac
    65221 atctgttaca ttgtattccc atgtccaagg gaacacactt tttccagtga accatgatcc
    65281 ttcaccaaac caagtacttg gtttgaacac ttcaccattc ccaatgattt ttttggaagc
    65341 ttcaacgaac caaactaaac catagaaaat acgaagtggc acactccata agacattgcc
    65401 gtaacgagaa gaatgtcctc gagtcacgtt gcgatcatct ttgatatgga aaaactcatg
    65461 cattaaatat tggaacatat aataaccaga acgaatatca aagaagtatt tcaaattcac
    65521 gatatgtttc attacgatag ctaaaaatcc gcttaaatgg atcttatcaa ataggttagc
    65581 taccccccat ttggcaccaa tagaaaccat aaatccttga tagtttcctt taaatttatg
    65641 cttttctccg cctttgatcg aagccacgat attcgctgcg gctgtgtgtc ctgtttgttc
    65701 agcagcttga acgatctgcg gtgtcggtgt tcctgggaat tcttcataaa agactaaatc
    65761 accaatgata tagatgtttt tatcttcgta gccttttgcc tgcatatatt cattggcgat
    65821 caaccgctgt ccgcgtgctg attctaatcc aaagtcagca gcgtcagaag ttcctttgac
    65881 accagctgtc caaatcagtg tgtgagtcgg aatgttgcgt ccgtctttca atttgatatg
    65941 atcagcagcc acttctacga ttggtgcatt caataataat tccacgttgt gcttacgcaa
    66001 atagcgttca gcttttgcag catcatttcg atccaacata ttcaagatcg tcggcattgc
    66061 ctctacgacc atcagtgtga tttcgtttgg atctaattta taatctttgg ctaggcgatt
    66121 tttccagtcg atcagttccc caatcatttc aataccggta aatccagaac cacagacaac
    66181 gaaagtcagc atggctttac gcagttcatc atctggttcc aatgcagctt ttgctactgt
    66241 cttctcaata tgttcccgaa tccttacaga atcttcaaat gaccaaaggg tgaatccgtg
    66301 tgctttgaca ccaggtgtac caaagtcatt cggctctccg cccattccaa ggatcagctg
    66361 atcaaaagga taggaaccta atttggtctt gacgattttt cgttctttat cgataccgat
    66421 tacagtgtct gtgacaagtt gtacattctt ttgacgagca aacaaatgct gcagatcgta
    66481 ttggattgct tctggttcta cacgtccgcc agctacttca tgcaactcgg tcatcatagt
    66541 atggtacgaa tgacgatcga tcagagtaat tgctacatct tcttttttca gtttctttgc
    66601 caagtatttt gtagctgaaa caccggcata tcctgctcct acaacgacaa tattttgctt
    66661 tgccattgat catccgctcc ttatagacta tctatataat gaatatatga taattctttt
    66721 agtttgatac ttattacaca atctccatat attatataga tgttctgttc ttttgtctaa
    66781 ctccttttgg atttttttca aattttaaaa taaagcgttt tttcacgaaa tttgctgaaa
    66841 gaaaacgttt gaaatattac atgggttatt tatcaaaaat agttgactta taggctaaaa
    66901 agattagaat gtataatgaa tcacaaagaa aaattgtgga ctagaaatgg aatggtgggg
    66961 tattaaaatg aagaaaaaac gttttgtaac tggatttgcc gtattagcat tttcagctct
    67021 agtgttaggc gcttgcggcg cagatgacaa cggaagctca aactcttctt ctgaatcatc
    67081 tacagcacaa tcttcgactg caaaaagcac aacagaatca tctgcaaaag ttgtagctgg
    67141 cggagatttg caagacggca catataaatt agaagaaaaa aattattcaa atggttaccg
    67201 tgcagtcttt gaaatggttg taaaagacgg caaaatcact gaatcaaaat atgataacgt
    67261 caatgaaaac ggcgaatcaa aaacaaaaga tgcagaatac aacaaaaaca tggaagcaaa
    67321 atctggcaca aacccagaaa aatacattcc tgagttgaat gaccaattct taaaagcaca
    67381 aagcgcaagc ggtgtggaag tcgtaactgg agctactcac tcatctgaaa gcttccaaaa
    67441 ctacgcacaa caattgatcc aagctgctca agctggtaac acagatacaa tcgaaatcga
    67501 caatggtgct gatttgaaag acggcactta caagcttgaa gaaaagaact actctaacgg
    67561 ctaccgtgtg caattcgaaa tgacagttgc tggcggcaaa gtaactgaat caaactttga
    67621 ttatatcgac aaagacggta aatcaaaaca agatgataca gaatataatg aaaatatgaa
    67681 agcaaaaagc ggtacagaac caaaaactta catccctact ctgaacgacg aattcgtcaa
    67741 agcaatgggc gaagaagatg gctcacctgc taatgtagaa gttgttacag gtgctacaca
    67801 cagctcacat tcattcatca tgtacgcaca acaattagtg aatgcagctg aaaaaggcga
    67861 cactcaaaca atcgaagtag ataatatcgt aacagaaaaa taatcacata atcatactaa
    67921 taaaagttgg agggtgggac gatagccaga ttaggcagtc gtctcacctt tcaaaatgaa
    67981 gagaggaaaa agatgcggaa aaaactacta ttttccttaa tcacactggg catctctttt
    68041 atggtgctaa ctggctgcag caactcagca aataaaacaa ccactgaaag ttcagcagct
    68101 accaagatat tgaaagatcc atattctgat gaacagttct tgttagggac ttacgttcgt
    68161 atccgtgtgt atgatgaagg caaagaatca gcattgaaac ctgccttcga tcgagtaaaa
    68221 gaacttggtg ataaaatcac gatcaatcaa aaaggttctg agatcgatga agtgaatgag
    68281 caagctggga tcaaaccagt aaaagtttct gatgacgtct acacgttagt caagcgggcc
    68341 tacgaatata gccaagattc tcaaggcgga ttcgatatgg cgattggtgc aatcacacaa
    68401 ttatggcgaa tcggttttga tgacgccaga aaaccttccc aagaagaaat cgatcaggca
    68461 ttgaaattag tggattatca taagatcgaa ctaaatgaca aagaaaaaac tgtttatcta
    68521 aaagaaaaag gaatgatcat cgatttaggt gcaatcgcca aaggttacat tacggacgaa
    68581 gtagtgaaag tcttgaaaaa acaaggagtg accactgcca tcgttgactt gggcggtaat
    68641 gtctatgtct taggccacag cccaagaggc gaaaaccaag actggacagt cggcatccaa
    68701 gatccgaaca tggctcgcgg atctgtttta ggttctatta aagaacggaa caaaacatta
    68761 gttacctctg gaatttacga gcgttattta gaagtagatg gcaaaaaata ccatcatttg
    68821 tttgatccaa aaacgggtta tccgttcgac aatgatatcg caagtgtcac gatcataaca
    68881 gataaatcaa ttgatggtga cgggttgtct acagcagtct tttcaatggg tgtgaaaaaa
    68941 ggactggaat acgtcgaaag cgaattgaat aacgggacgg aagcgatctt cgtgacaaaa
    69001 gacgataaag tatatgtgac cgatccaatc aaagacacct tcaaattatc ggaggactcc
    69061 cattacacga tgggtgaccg ttctgaacta aaataaggag tacgaaccat gacactaaaa
    69121 atctttttag aagtagttga aatacgaaca aaggtggcta gtgtatttcc ttttgcggta
    69181 ggggtattat tctctatcgc tttttttcat gagatacatt ggctaaacac ttttttattt
    69241 tttattggaa tgctagtttt tgatttagcg actaccgcta tcaataatta catggattat
    69301 gaaaaggctc attctgaagt atataagtat gaagaaaatg tcattggccg cagaaatcta
    69361 tctcctgtat tgattcgaaa catgatttta gctatgattg catttgtttt tgttatcggc
    69421 gttattctaa cgatcaatac gggttggctt ttacttttga tgggatttat ctgttgtttt
    69481 attggagtat tctatacatt cggaccgatt cctttatctc gaatgccttt aggggaaatt
    69541 ttcagtgggg tgactatggg ccttggaatt tttgccatgg tcgtttatgt caatacattc
    69601 ggttcagatg tctatgatct gacagtcaac ttttcatctg gacaatttgc tttggtagga
    69661 aatctttggg ctatagcagc aatcgtatta gcttccttac ccttggtgtt tacgattgcc
    69721 aatatcatgt tggctaataa tttgcgggat cttgaccgtg atattgaaaa tcatcgctat
    69781 acactagttt tttatatcgg acgtcctgcg ggaacagtct tattccagct attgatgtat
    69841 gcttgctatt tcgtgatttt aatggggttg ttgagcggta tctatgaatg gccgatcttg
    69901 gtcaccttct tgaccttgcc aattgtgaag aagcatttgg atcaattcaa gcaaacgtta
    69961 ccccagccta tcagtttcag ctattccatc aaaaatatgg tcttattcaa tgccagttat
    70021 gtattggggc tattactaac aatcattatg caagccattt aacagcatga agaggttgtg
    70081 aaaaaactgc cctgcatcaa gtaataagaa cagccaaata aaaatagctc cttatatttt
    70141 tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta tcaggaggtt
    70201 gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat
    70261 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt tatcagaggt
    70321 tgtaaaatca gtgttttgtc ctgagtatta gagaaacaaa tggaaaaata gttcctcata
    70381 ttttgccgtt ttttgagcta ataccgaagg acagctgatt gaacactatt tgttcggaaa
    70441 aagtgactaa ctatgacaca atttttttca cagtcccttt tttcacttga tttgattcgt
    70501 accagcgaac ttgacgagaa ctttcttggt ttggtaacta tatggtattc ttttaacatc
    70561 ctcgtttgct tcttctaatt tatttataca aagtcacact tttttaaaca tctgttcttc
    70621 gatacatttc tatttctttt aaacatcgat accaatattt tgaacttaag agtgcatacc
    70681 aaatggattc atttactctt cgtcagttac gaagataatc aaaatctcca acttccctac
    70741 ttatttcgtt ttgagaatta tcgaagcaat cttacataaa taactaaaaa acaaaaaacc
    70801 agaaaatcag tatactgatt ttctggtttt acatggtttg ttcaataaaa agctgttgga
    70861 actgttaata ttaaattatc gcatcgttac gaattcttcc gctcctgttg gatggatggc
    70921 tactgtattg tcaaagtctt ctttagttgc acccatcttg atagccacgg caaaaccttg
    70981 cagcatctca tcgacaccaa caccaatagc atgtaagccg acgattcttt cttcttttcc
    71041 gacacagatc aatttcattt cgcatttttg gcgataatca tttaatgcaa agtacattgg
    71101 ggtaaagcgt gaacgataaa ctttcaattc attttcgcca tatttttcca atgcttcttc
    71161 ttctgtcaaa ccaattgttg caattggtgg atgcgtaaag acgactgtcg gaacaagttt
    71221 atagtcaaga taagaatctt tctttccatt aaataaacgt tctgataaac gtctaccagc
    71281 tgcgattgca acaggagtca gatctaattt accgatcaca tcaccaacag caaaaatatg
    71341 ttcatccgtt gtattttggt atttatctac tttgataaac ccttttttgt ccaattccac
    71401 atttgtattt tccagaccta atttttcggt attcggtaca cgtccaccgg caaaaagtac
    71461 acaatcacca gttaaggttt caccattttc aaatagcacc gtatattcgt cattgttttt
    71521 agtaatttct ttagcaatat gatgtgcgta agtttttatt ccagcttctt ggtacatttg
    71581 gatcaaattg tccgaaagca ttttatcaaa cgttctaagt ggtcgttctt ttcgatatgc
    71641 ccacatgact tcactaccta aaccacgaaa tacacctgaa agttcagccg caatgtatcc
    71701 agcacctaaa acgattgctc tcttaggtaa ctctgttaat tcaaaaaatc catttgaatc
    71761 aattgcgtat tctccaccag gaatggtcat tttacttgca cggcctccag tagcgatcaa
    71821 gattttagga gcacgatagg tttcaccgtt tacttcgatc gtttgactat cgataaaagt
    71881 agcgtaacct tttatagcct cgacatgatt gctatctaat cctctttgat aagcaccgtg
    71941 tagaaaatca atatattttt ctcgtctttc tactagaccg gcgaaatcaa cattttttaa
    72001 atctgcttgg ataccgtaac ttgaggcatc tcgttcaatt gtttccaaaa tcgtacttgc
    72061 ttgccacata acttttttag gtacacaacc gacgttgaca catgttccgc ccaattcatt
    72121 cgcttcaatc agcaaaactt ttgcgccatg catccctgct ctgtttgctg aagcaatacc
    72181 gccagagccg ccaccaatta cgatgtaatc atatatttgc attttgttcc tccttattga
    72241 agagatcaat caaaaccttt atttaacgat cctttttcta cagaaaacaa gtgtaacact
    72301 tttcttgaat tttgtatgcg aagatgctta aaacagggat atatcagctt tttccttatt
    72361 tacgttttcg gatcatatct ccaggtttca ccggctgtgc gactggcata gttaaaatca
    72421 tcattggatt tggtgctcgg tcaatggatt cgccttcttc attatgcata acttcaacgg
    72481 tttgactgaa atgactgaat cctggaccat aaaattcgat ttcatctcct acagaaaaca
    72541 agtttctctg acgtatcgta gcaatctgtg ttgcctcatc ataagataat acttcaccga
    72601 caaatttata tactgggatt ttacgacgtt caccgaataa ttgttcgttt tcagttggtg
    72661 tattgtagta aaaacctgta gctaattctc gttgtgctac tttccataac tcgtcgatcc
    72721 attcttgctt gcagacatag ttttcaggat cttccatata actgtctaca gccgctttat
    72781 agacatttga caccgtagat acataatgga tcgatttcat tcttccttcg atcttgaagc
    72841 tgtctacgcc gttttcaatc aattctggaa tatgttcgat cattgacata tccactgcac
    72901 tcatcgagaa ttcttcttcc acttcgcctg tatcagttaa actgtttcgt tcttgaccaa
    72961 aaggcatatc gaacaatcca tacttccagc gacaagattg agaacatccg ccacggtttg
    73021 catcccgcat cgacatatgg ttggacaatg tgcatcgacc agaataagag atacacatgg
    73081 caccatggat aaatgcttcg atttcggtat ccgtattttt acgaatctct gccacttcct
    73141 ccattgaaac ttcacgagct aaaacgacac gttccaaccc ttcttctttc cagaattcca
    73201 atgtctcaaa attagttgct gaagcttgag tggataaatg gatcggcaga cctggggctt
    73261 ctgtcgcaca aatttcgatc aaagctggat cagaaacaat cactgcagaa ataccgacat
    73321 cacgcaaact gcggaaaaat tcccctgctc catcttcatt tccttcatgg gtgaccatat
    73381 tagcagcaac gtataccttc gcatcatgtt cttttgcaaa agcaactcct tcagccattt
    73441 cttcataagt aaaattacct gcacggcttc ttaaaccata tgcattcccg ccaatatata
    73501 ctgcatctgc tccataatgg atcgcggttt ttaacttttc cagtgttcct gctggcgcta
    73561 ggatttctgg tcgtttcaat tttcttttta ctgtcatttc tttcatcata ctccttattt
    73621 gatagcagaa ggatcaatat aaaagaatcc tgtatctaat tcacggtttt caggatgcaa
    73681 tttactgatt tcgctagtca ttttttccgc tttttcttga tcccagctac cttctaaaat
    73741 ttgttttttt gcttcggcga atagtcgagt gatgtttacg aatttttcgc ctggagtaaa
    73801 taatccgtcc aatttccatg tacagtaatg atgctgataa agttcattca attcattcga
    73861 gagattcaga tcattgctgg caaaaatatg tgtgccatga ctatcttcat aaatagaata
    73921 atgtgtctct tcttttttag gttccgagat aaaaagacct ctttcacgat ctttttgttc
    73981 gtcttgtttc gtatagttat agtaattctg tagcagtgga cgtttggatt gatggatgca
    74041 tgtagcacca tacacaaggg tttctacagg aatatcgagt ttttcttcca tcgccttcat
    74101 ctcttcaaaa ggaacttcac gagcaagtac tgctccaact gcgccttttt tcgcccagaa
    74161 attgatttga cgtgcgctcg ttactaatgt ttcagcatca taaatatacg gtatacgcaa
    74221 ttcaggattt tttttcatcg tataaataat acctgtatca ccaactgtga tcacatctac
    74281 gtttatttct tttaaaaaag ccaaatattc aggtacattt ttcatttttt caggatgaat
    74341 gatcccattt acagcaatat tcgctttttt accatacttg tgtgctaatt ctaccaattg
    74401 tcgctgttct tctcgtgtaa atgaagcagg cagacgcaat ccaaattgct cttcaccgaa
    74461 atatagtgta tctgcacctg cagcaagcaa ctgttctgct tgttcaatag tttctactgt
    74521 ggttatgagt tcgatcataa ttttctcctc ctacaacttc ataatagtag catagctcta
    74581 aaaactttcc aatacttctt ctatttaaag tcggattttt gaaaattatt tcacaaaaaa
    74641 tcaaaataaa gttcgatata ttctgtccaa atataaaaag agattgtgac aaaaatcttg
    74701 tcacaacctc ttaatcaagt cttactatta taaaaattca gctacacagg ccaagtaact
    74761 atagggaacc tactgtttcc tttttaggtc cgcgaacatt caatgtgatc ttaccttttg
    74821 aagcacctac tgttacgtgg tcacctaaac gaatttctcc gccaagcaaa gcctcgctca
    74881 atcgatcttc aatttctttt tgaagtgcgc gacggattgg acgtgcacca tattcaggat
    74941 caaatccagc tttcccgatc acatcgattg cagatggtgt gattttcact tgaatatctt
    75001 gttctttcaa tcgtttgata atcgctttgc tcatgatttg gacgattgta tggatttcat
    75061 ctttactcaa tgaatggaag acgacagtct catcgattcg attcaagaat tcaggtcgga
    75121 aagctttctt taactcttct aagatacgtt tttgcatggc tttgtgatct ttagtaacat
    75181 cttggacatt gaatccgaca tttttttctt ctcgaatttg tgtcgctccg atatttgaag
    75241 tcataatcat gattgtattt ctaaagtcca cttttctacc tttagaatct gttaaatgac
    75301 catcatccaa tacttgcaga agtaaattga aaacgtctgg atgtgctttc tccacttcat
    75361 ctaagagaat cactgaatat ggtttttgac gaattttttc tgtcaactgt ccaccttcat
    75421 cataccctac gtatcctgga ggagacccga ttaatcggct tgtactgtat ttttccataa
    75481 attctgacat atcaacacgg atcagggcat cttcacttcc aaacatgact tctgaaagtg
    75541 ctttggccaa ttctgttttt ccgacaccag ttggtccaag gaacatgaat gaaccaattg
    75601 gacgatcagg atctttcaat ccgcttcgtg cacggcggat cgcacgtgaa actgctttga
    75661 cagcctcatc ttgaccaacg acacgttcat gcagaagtcc ttccagttct aacaagcgtt
    75721 cgctttcttt tttctccaac tgctgtagag ggacaccagt ccactccgat acaactgtag
    75781 caacatcttc ttctgttaca cgatcagaat aaccttgctc ctgttttgct tcaattgcag
    75841 aaactttttg cagcttttta cgtagtgctt tttcttgtct gcgtaattga gcagcatttt
    75901 caaagtcttg tttttggatc gctgcttcct tttcttgtac tagttcatcg atttctagtt
    75961 tgatcacagt tgattttgtt aagtgatcgg tttgatccaa acggactttc gctgctgatt
    76021 catcgatcaa atcaattgct ttatcgggta gttgacgaga agtgatataa cgaacagaaa
    76081 gattgactgc tgctcgtaca gcttcatctg tgatctccac tccatggtgc tcttcatatc
    76141 ttgtacgtaa tccttgaaga atcacttctg cttcttcagg agttggctca tctacttgaa
    76201 tgcgagcaaa acgtcgctct aatgcagaat ctttttcgat atatttttga tattcatcta
    76261 gggtcgttgc tccgatcgtt tgtaattctc ctcgagctaa cgccggtttc aagatattcg
    76321 aagcatcaat tgctccttct gctccacctg caccaattaa ggtatgcaat tcatcaatga
    76381 ataagattac ttgaccatca ttatagattt cgtcgatgac ctttttcatt cgatcttcaa
    76441 attcaccgcg atatttcgta ccagcaacca aagatcccat atcaagcatc atcaggcgct
    76501 tttcttgcat gtcttctggc acttcaccta aaatgatttt ttgagctaac ccttcagcaa
    76561 tggctgtttt gcctacacca ggttcaccca ccagtacagg gttattcttt gtccgtcggc
    76621 taagaatctg gataagccgt ttcacttctc tcgaacgacc aacaactggg tccagcttgt
    76681 tttcttttgc taatttcgtc aaatcacgtg ctaatgaatc tagcgtaggt gttccttgcg
    76741 gtgtttgccg tttatcttgt acatttacat ttctacgacg attcattcct tttccagcag
    76801 aatcaccagc tagccccatt ttttgtttca gaacttgacg ggcttttgaa aggctgatac
    76861 ctaagttgat catgattcga gtagccatga tactttcatc ttttaataag ctcatcaaaa
    76921 tatgttctgt tccaactttt tgagaaccag ttttcttcac ttcgctgcta gctaaagcaa
    76981 aaacttgttt cattcttggt gaatatggaa gaaagactcc tttagggtaa gaacggatac
    77041 caccataacc aatcagatgt tcaatttctt cataaatttc cgtttcattc aaatccattt
    77101 cacgtaatac ttttccagca attccatttt gctcgaccac taaggctagt aaaacatgtt
    77161 ctgaactaac tgattgatgt ttcaaccgtt ttgcttcttc ttgtgcaatt tctaatactg
    77221 cttgggctct ttcagtaaaa agttcttcca tctaatctca cttcccatct tcataactta
    77281 aacgttccag aaatgctcgg agaatccgag cacgtgtatg atcttcatat tcattgaaat
    77341 tcaatgtgtt ttttgcaatt gcactcaaca tcaagtttcc ttcttttttt gtaattattt
    77401 ggtcttcata aagtttttga ataatagcaa aagcattttt ctcactgatt gtatcatcaa
    77461 ataactgatt tatctgctca agtaattgtt ttttatctga aatccttact tttgcaattc
    77521 gtatataacc accaccacca cgtttgcttt ctactagata accacgttgg atggtaaaac
    77581 gggtattaat cacatagttg atttgtgaag gaacacagtt aaagaggtct gccatttcaa
    77641 tccttcgaat ctcgatcatt tcactatttt ccagaatttt ctttatatat gattcaatta
    77701 aatccgaggt attctgatgt gccatcttat tcattccctt tgactaatat tgaccttaat
    77761 tataacgaat ttgataatag aaagaaagaa gaacgctttt tgttaaataa atcctttaga
    77821 atcaacaaaa aaaaatacgg aatatactat tccgtatcga cgcgcccaag aggagtcgaa
    77881 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattc
    77941 aatttaaaaa aattataaat catttgaaaa caaaaagcaa gataaaaaaa atcgggaaga
    78001 caggattcga acctgcgacc ccttggtccc aaaccaagtg ctctaccaag ctgagctact
    78061 tcccgtttaa aaaataaaaa agac
//
LOCUS       DASHXG010000008        65794 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.008, whole genome shotgun sequence.
ACCESSION   DASHXG010000008 DASHXG010000000
VERSION     DASHXG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.008"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            476..1339
                     /locus_tag="U2R59_000645"
     CDS             476..1339
                     /locus_tag="U2R59_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8965063.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="U2R59_000646"
     CDS             complement(1468..3090)
                     /locus_tag="U2R59_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965064.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="U2R59_000647"
     CDS             3339..3860
                     /locus_tag="U2R59_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEM8965065.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="U2R59_000648"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="U2R59_000648"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEM8965066.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="U2R59_000649"
     CDS             5941..6759
                     /locus_tag="U2R59_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HEM8965067.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="U2R59_000650"
     CDS             complement(6862..7059)
                     /locus_tag="U2R59_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965068.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="U2R59_000651"
     CDS             7228..7806
                     /locus_tag="U2R59_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEM8965069.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="U2R59_000652"
     CDS             7901..8038
                     /locus_tag="U2R59_000652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965070.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="U2R59_000653"
     CDS             complement(8851..9354)
                     /locus_tag="U2R59_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEM8965071.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="U2R59_000654"
     CDS             9713..10738
                     /locus_tag="U2R59_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8965072.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="U2R59_000655"
     CDS             11061..11939
                     /locus_tag="U2R59_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HEM8965073.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="U2R59_000656"
     CDS             12415..12531
                     /locus_tag="U2R59_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEM8965074.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="U2R59_000657"
     CDS             13459..13797
                     /locus_tag="U2R59_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965075.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="U2R59_000658"
     CDS             13891..14121
                     /locus_tag="U2R59_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965076.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="U2R59_000659"
     CDS             14521..14892
                     /locus_tag="U2R59_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HEM8965077.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="U2R59_000660"
     CDS             complement(15166..15858)
                     /locus_tag="U2R59_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8965078.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="U2R59_000661"
     CDS             complement(15861..16646)
                     /locus_tag="U2R59_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8965079.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="U2R59_000662"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="U2R59_000662"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEM8965080.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="U2R59_000663"
     CDS             18308..18625
                     /locus_tag="U2R59_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEM8965081.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="U2R59_000664"
     CDS             18638..20311
                     /locus_tag="U2R59_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HEM8965082.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLEIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="U2R59_000665"
     CDS             20325..21956
                     /locus_tag="U2R59_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HEM8965083.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="U2R59_000666"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="U2R59_000666"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEM8965084.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /locus_tag="U2R59_000667"
     CDS             complement(24071..24994)
                     /locus_tag="U2R59_000667"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEM8965085.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="U2R59_000668"
     CDS             25190..25795
                     /locus_tag="U2R59_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8965086.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="U2R59_000669"
     CDS             26103..27119
                     /locus_tag="U2R59_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEM8965087.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="U2R59_000670"
     CDS             27260..28561
                     /locus_tag="U2R59_000670"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEM8965088.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="U2R59_000671"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="U2R59_000671"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEM8965089.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="U2R59_000672"
     CDS             29290..29688
                     /locus_tag="U2R59_000672"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEM8965090.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="U2R59_000673"
     CDS             29754..30836
                     /locus_tag="U2R59_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8965091.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="U2R59_000674"
     CDS             31048..32610
                     /locus_tag="U2R59_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965092.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="U2R59_000675"
     CDS             32603..33736
                     /locus_tag="U2R59_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965093.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="U2R59_000676"
     CDS             33736..34692
                     /locus_tag="U2R59_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965094.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="U2R59_000677"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="U2R59_000677"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEM8965095.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="U2R59_000678"
     CDS             35981..36799
                     /locus_tag="U2R59_000678"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEM8965096.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="U2R59_000679"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="U2R59_000679"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEM8965097.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="U2R59_000680"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="U2R59_000680"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEM8965098.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="U2R59_000681"
     CDS             complement(38679..39260)
                     /locus_tag="U2R59_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8965099.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="U2R59_000682"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="U2R59_000682"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEM8965100.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="U2R59_000683"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="U2R59_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEM8965101.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="U2R59_000684"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="U2R59_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEM8965102.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="U2R59_000685"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="U2R59_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEM8965103.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="U2R59_000686"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="U2R59_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEM8965104.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="U2R59_000687"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="U2R59_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEM8965105.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHEYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="U2R59_000688"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="U2R59_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEM8965106.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="U2R59_000689"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="U2R59_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEM8965107.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="U2R59_000690"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="U2R59_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEM8965108.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="U2R59_000691"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="U2R59_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEM8965109.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="U2R59_000692"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="U2R59_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEM8965110.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="U2R59_000693"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="U2R59_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEM8965111.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="U2R59_000694"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="U2R59_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEM8965112.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="U2R59_000695"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="U2R59_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEM8965113.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="U2R59_000696"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="U2R59_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEM8965114.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="U2R59_000697"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="U2R59_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEM8965115.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="U2R59_000698"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="U2R59_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEM8965116.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="U2R59_000699"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="U2R59_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEM8965117.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="U2R59_000700"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="U2R59_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEM8965118.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="U2R59_000701"
     CDS             51714..51899
                     /locus_tag="U2R59_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEM8965119.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="U2R59_000702"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="U2R59_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEM8965120.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="U2R59_000703"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="U2R59_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEM8965121.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="U2R59_000704"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="U2R59_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEM8965122.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="U2R59_000705"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="U2R59_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEM8965123.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="U2R59_000706"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="U2R59_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEM8965124.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="U2R59_000707"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="U2R59_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEM8965125.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="U2R59_000708"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="U2R59_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEM8965126.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="U2R59_000709"
     CDS             55974..56621
                     /locus_tag="U2R59_000709"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEM8965127.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="U2R59_000710"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="U2R59_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEM8965128.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="U2R59_000711"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="U2R59_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEM8965129.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="U2R59_000712"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="U2R59_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEM8965130.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="U2R59_000713"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="U2R59_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEM8965131.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="U2R59_000714"
     CDS             58059..58997
                     /locus_tag="U2R59_000714"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEM8965132.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="U2R59_000715"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="U2R59_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEM8965133.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="U2R59_000716"
     CDS             59677..60516
                     /locus_tag="U2R59_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8965134.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="U2R59_000717"
     CDS             60492..61361
                     /locus_tag="U2R59_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8965135.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="U2R59_000718"
     CDS             61351..62148
                     /locus_tag="U2R59_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEM8965136.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="U2R59_000719"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="U2R59_000719"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEM8965137.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63762..63999
                     /locus_tag="U2R59_000720"
                     /pseudo
     CDS             63762..63999
                     /locus_tag="U2R59_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="U2R59_000721"
     CDS             complement(64143..64919)
                     /locus_tag="U2R59_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8965138.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..65449
                     /locus_tag="U2R59_000722"
     CDS             65042..65449
                     /locus_tag="U2R59_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HEM8965139.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20924 a        11726 c        13857 g        19287 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttagaaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcatgaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
    65401 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
    65461 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
    65521 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
    65581 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
    65641 gtatcctgtc acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt
    65701 agaaatattt gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa
    65761 agaccaacag ggtataccct gttggtctaa ataa
//
LOCUS       DASHXG010000009        64728 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.009, whole genome shotgun sequence.
ACCESSION   DASHXG010000009 DASHXG010000000
VERSION     DASHXG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.009"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(25..1005)
                     /gene="pta"
                     /locus_tag="U2R59_000723"
     CDS             complement(25..1005)
                     /gene="pta"
                     /locus_tag="U2R59_000723"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEM8965140.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(1158..1838)
                     /locus_tag="U2R59_000724"
     CDS             complement(1158..1838)
                     /locus_tag="U2R59_000724"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEM8965141.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            1964..2833
                     /locus_tag="U2R59_000725"
     CDS             1964..2833
                     /locus_tag="U2R59_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8965142.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            2859..3374
                     /locus_tag="U2R59_000726"
     CDS             2859..3374
                     /locus_tag="U2R59_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965143.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(3421..4014)
                     /locus_tag="U2R59_000727"
     CDS             complement(3421..4014)
                     /locus_tag="U2R59_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8965144.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(4039..4218)
                     /locus_tag="U2R59_000728"
     CDS             complement(4039..4218)
                     /locus_tag="U2R59_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965145.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(4295..4804)
                     /locus_tag="U2R59_000729"
     CDS             complement(4295..4804)
                     /locus_tag="U2R59_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965146.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(4900..5279)
                     /locus_tag="U2R59_000730"
                     /pseudo
     CDS             complement(4900..5279)
                     /locus_tag="U2R59_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644319.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            5609..6358
                     /locus_tag="U2R59_000731"
     CDS             5609..6358
                     /locus_tag="U2R59_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEM8965147.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(6542..7819)
                     /locus_tag="U2R59_000732"
     CDS             complement(6542..7819)
                     /locus_tag="U2R59_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965148.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(7898..8542)
                     /gene="pcp"
                     /locus_tag="U2R59_000733"
     CDS             complement(7898..8542)
                     /gene="pcp"
                     /locus_tag="U2R59_000733"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEM8965149.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(8741..9685)
                     /locus_tag="U2R59_000734"
     CDS             complement(8741..9685)
                     /locus_tag="U2R59_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEM8965150.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(9687..10373)
                     /locus_tag="U2R59_000735"
     CDS             complement(9687..10373)
                     /locus_tag="U2R59_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEM8965151.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            10847..11167
                     /locus_tag="U2R59_000736"
     CDS             10847..11167
                     /locus_tag="U2R59_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEM8965152.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            11321..12226
                     /locus_tag="U2R59_000737"
     CDS             11321..12226
                     /locus_tag="U2R59_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965153.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            12223..12996
                     /locus_tag="U2R59_000738"
     CDS             12223..12996
                     /locus_tag="U2R59_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8965154.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(13177..14601)
                     /locus_tag="U2R59_000739"
     CDS             complement(13177..14601)
                     /locus_tag="U2R59_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965155.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            14812..15258
                     /gene="nrdI"
                     /locus_tag="U2R59_000740"
     CDS             14812..15258
                     /gene="nrdI"
                     /locus_tag="U2R59_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEM8965156.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(15323..17305)
                     /locus_tag="U2R59_000741"
     CDS             complement(15323..17305)
                     /locus_tag="U2R59_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8965157.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(17319..18215)
                     /gene="murQ"
                     /locus_tag="U2R59_000742"
     CDS             complement(17319..18215)
                     /gene="murQ"
                     /locus_tag="U2R59_000742"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEM8965158.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(18218..19279)
                     /locus_tag="U2R59_000743"
     CDS             complement(18218..19279)
                     /locus_tag="U2R59_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8965159.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(19490..20056)
                     /locus_tag="U2R59_000744"
     CDS             complement(19490..20056)
                     /locus_tag="U2R59_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8965160.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(20084..21586)
                     /gene="eat(A)"
                     /locus_tag="U2R59_000745"
     CDS             complement(20084..21586)
                     /gene="eat(A)"
                     /locus_tag="U2R59_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEM8965161.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(21844..22965)
                     /locus_tag="U2R59_000746"
     CDS             complement(21844..22965)
                     /locus_tag="U2R59_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8965162.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            23091..24032
                     /locus_tag="U2R59_000747"
     CDS             23091..24032
                     /locus_tag="U2R59_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEM8965163.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(24182..25078)
                     /locus_tag="U2R59_000748"
     CDS             complement(24182..25078)
                     /locus_tag="U2R59_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEM8965164.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            25347..26687
                     /locus_tag="U2R59_000749"
     CDS             25347..26687
                     /locus_tag="U2R59_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965165.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            26905..27348
                     /locus_tag="U2R59_000750"
     CDS             26905..27348
                     /locus_tag="U2R59_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEM8965166.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(27852..29270)
                     /gene="nhaC"
                     /locus_tag="U2R59_000751"
     CDS             complement(27852..29270)
                     /gene="nhaC"
                     /locus_tag="U2R59_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEM8965167.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(29673..30896)
                     /locus_tag="U2R59_000752"
     CDS             complement(29673..30896)
                     /locus_tag="U2R59_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HEM8965168.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(30927..31766)
                     /locus_tag="U2R59_000753"
     CDS             complement(30927..31766)
                     /locus_tag="U2R59_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEM8965169.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(31783..32463)
                     /locus_tag="U2R59_000754"
     CDS             complement(31783..32463)
                     /locus_tag="U2R59_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965170.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(32465..33538)
                     /locus_tag="U2R59_000755"
     CDS             complement(32465..33538)
                     /locus_tag="U2R59_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965171.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(33594..33832)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(33875..34108)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(34185..34856)
                     /locus_tag="U2R59_000756"
     CDS             complement(34185..34856)
                     /locus_tag="U2R59_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8965172.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(34943..37621)
                     /gene="mgtA"
                     /locus_tag="U2R59_000757"
     CDS             complement(34943..37621)
                     /gene="mgtA"
                     /locus_tag="U2R59_000757"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HEM8965173.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            38280..38717
                     /gene="ndk"
                     /locus_tag="U2R59_000758"
     CDS             38280..38717
                     /gene="ndk"
                     /locus_tag="U2R59_000758"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEM8965174.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(38739..39605)
                     /locus_tag="U2R59_000759"
     CDS             complement(38739..39605)
                     /locus_tag="U2R59_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8965175.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(39765..41858)
                     /locus_tag="U2R59_000760"
     CDS             complement(39765..41858)
                     /locus_tag="U2R59_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8965176.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(42607..43230)
                     /locus_tag="U2R59_000761"
     CDS             complement(42607..43230)
                     /locus_tag="U2R59_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965177.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(43389..44786)
                     /locus_tag="U2R59_000762"
     CDS             complement(43389..44786)
                     /locus_tag="U2R59_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8965178.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(44818..45789)
                     /locus_tag="U2R59_000763"
     CDS             complement(44818..45789)
                     /locus_tag="U2R59_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965179.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            46163..46588
                     /locus_tag="U2R59_000764"
     CDS             46163..46588
                     /locus_tag="U2R59_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965180.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(47076..47777)
                     /locus_tag="U2R59_000765"
     CDS             complement(47076..47777)
                     /locus_tag="U2R59_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8965181.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(47793..48233)
                     /locus_tag="U2R59_000766"
     CDS             complement(47793..48233)
                     /locus_tag="U2R59_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEM8965182.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(48233..48808)
                     /locus_tag="U2R59_000767"
     CDS             complement(48233..48808)
                     /locus_tag="U2R59_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HEM8965183.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(49656..50135)
                     /locus_tag="U2R59_000768"
                     /pseudo
     CDS             complement(49656..50135)
                     /locus_tag="U2R59_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(50294..50995)
                     /locus_tag="U2R59_000769"
     CDS             complement(50294..50995)
                     /locus_tag="U2R59_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8965184.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(51103..52512)
                     /locus_tag="U2R59_000770"
     CDS             complement(51103..52512)
                     /locus_tag="U2R59_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEM8965185.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(52560..54425)
                     /locus_tag="U2R59_000771"
     CDS             complement(52560..54425)
                     /locus_tag="U2R59_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8965186.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(54546..55396)
                     /locus_tag="U2R59_000772"
                     /pseudo
     CDS             complement(54546..55396)
                     /locus_tag="U2R59_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(55706..56419)
                     /locus_tag="U2R59_000773"
     CDS             complement(55706..56419)
                     /locus_tag="U2R59_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEM8965187.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(56487..56813)
                     /locus_tag="U2R59_000774"
     CDS             complement(56487..56813)
                     /locus_tag="U2R59_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HEM8965188.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(56936..57163)
                     /locus_tag="U2R59_000775"
     CDS             complement(56936..57163)
                     /locus_tag="U2R59_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEM8965189.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(57485..58738)
                     /locus_tag="U2R59_000776"
     CDS             complement(57485..58738)
                     /locus_tag="U2R59_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEM8965190.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            58799..59539
                     /locus_tag="U2R59_000777"
     CDS             58799..59539
                     /locus_tag="U2R59_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965191.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(59625..60383)
                     /locus_tag="U2R59_000778"
     CDS             complement(59625..60383)
                     /locus_tag="U2R59_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8965192.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(60380..61408)
                     /locus_tag="U2R59_000779"
                     /pseudo
     CDS             complement(60380..61408)
                     /locus_tag="U2R59_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(61428..64595)
                     /locus_tag="U2R59_000780"
     CDS             complement(61428..64595)
                     /locus_tag="U2R59_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965193.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
BASE COUNT        18566 a        13582 c        11243 g        21337 t
ORIGIN      
        1 ttttggctag ttcgcgtgta tttgttaatc aatcaatgtt tgtgctgctg tgataatcga
       61 taatttatat acatcttctt catttgctcc acgagacaaa tcagaaaccg gtttgttcaa
      121 gccttgtaga attggtccga ttgcttcaaa gttaccgaaa cgctgagcaa ttttatagcc
      181 gatatttcct gactgcaatt ctggaaatac aaagactgtt gcttgaccag ctacttctga
      241 atctggcgct ttcagttgtg caactgaagg aacataagaa gcatcaaatt gcaattcgcc
      301 gtcgatcatg tattgtggcg ctagtttttt agcgatttta gttgcttcaa ctactttgtc
      361 tacttctggc gatttcgctg agccttttgt cgagaagctc atcattgcta cttttggttc
      421 gatatcgaac aattctgctg tttttgcaga atctacggcg atttcagcca attcttgcgc
      481 agttggattc acgttgatcg cacaatccga aaagacatat ttttcttgat ctcttccacg
      541 taccatgatc atcgctccgc ttgtccgact gatgccaggc tttgttttga tgatctgaag
      601 tgctgggcga acagtgtcgc cagtcgaatg gatcgctcca gagaccattc cgtctgcaat
      661 ccccatatac gtaagcatcg taccaaagta attcacatct tttaaaatct tttctgcttg
      721 ttctttggat gcctttccat ttctacgttc aacaaaagta tccaccattt catcccactt
      781 atcgtaatta tcagggctga tgatcgtaaa gctagatgtt ttgattcctc tggcatgcgc
      841 tgcatttctt atttcttctt cgttccctac taaaatgggt tccacaagtt cttctgcttt
      901 caaccgggca gctgcgccta aaatacgagc atcagtagct tccgggaaaa cgattttgat
      961 cccacggcga acaattttaa atcttaaact atcaaacaat tccacaagat gacctccaga
     1021 cgtttttata tgtattatca tacactattc cagaaaaaaa gaacagttta ttttatctgt
     1081 atcagtcaaa aatgctggaa aaattaagtt tttcacatac aaagcgaact gcactataac
     1141 aggaaagcgc tgttttatta cactgtttca ggcagttgcc aatcaatcgg ttcttctcct
     1201 aacgcaagga gcgcatcatt cgttttcgag aagggtttgg aaccaaaaaa gccacgactt
     1261 gcagataacg gactgggatg tggagatgtt atgatgatat ggcgactctt atcgatcatt
     1321 ttgatttttt cttgtgccgg ttttccccac aagataaaca cgattggttt ttcccgttca
     1381 tttaattttt caatgatcgt gtctgttaat ctttcccaac ctttcccgcg atgagaatac
     1441 gcttgccctt cccgaacggt aagaacggtg ttgagtaaaa ggactccctg tttagcccat
     1501 gacactagat ttccatgttg aacaggtgcg attccaagat catcataaag ctctttatag
     1561 atatttctta acgatggcgg gatctttacg ccaggttgca cagaaaaaga taagccatga
     1621 gcttgatttt ctccatgata aggatcttgt cctaaaatca ccactttaac ttcttcataa
     1681 ggagtcaatt ccaatgcttc atagatatga tacatatctg gatggatctt ttgggacgca
     1741 tattcttttt ttaaaaattc tcttagatgc agataataat cttttgaaaa ttctgaggac
     1801 aaaacttctt gccaactgtt atgaatgatt tctttcaaaa actccacctc ctaataaaaa
     1861 gaataactca cattttcttc aatcacaagg gacaatcttc accctcagca cttgattaat
     1921 atggtaaact aggaacaaga agcagaaagg aacgataatc attatgatca aattaattgc
     1981 atcagatatg gacggcacat tattagatgc ccatatgagt gtttctcctg aaaatgccga
     2041 ggcgatacgt tttgcaaatg atgccggtgt tgagttcatg gtcgctactg gtcgaaacta
     2101 tcaagaagct cgcgcagctt tagatgaggt aggaatcgat tgtgcgatga tcactttgaa
     2161 cggggcacag gtatttgata aagaaggaaa ttcattgttt accgtgtcga ttccaaataa
     2221 tcaagcaatc tctgttttag atattctaga tgctaacggt atttactatg aagtagcaac
     2281 caacgatggt ctttattctg aaaatcaagc gaaacgaatt gaaagttttg cttccatggt
     2341 ggctacccat ttacctcacc ttacgtataa aatggcgatt gccatggcct cagctaagct
     2401 ggagttattg cacatcacat acgtggacag tattcgtgct attttggaag aaaagaatct
     2461 ggaagtttta aaaattattt gttttcatac agaagggcca gctgtattag gtccagttgg
     2521 aaagcagatt tctcttttag gcgatctagc cgttacttcc tctggtcaaa acaatatcga
     2581 agtgaaccat aaaaacgctc aaaaaggaat tgctgttgcc catgtcgctc acgagcgtgg
     2641 gatttcttta gaagaagtca tgacgattgg cgataacttc aatgatgtca gcatgctgca
     2701 agtagcagga gtcagtttcg caatgggaaa tgcagaaatc gaagtaaaag attatgccaa
     2761 atatacaacg gacacaaacc ttgaatctgg cgtaggaaaa gccatattgc gcgcgattgc
     2821 agaagacttg tagttttatc tagaaaagag ggatatagat gtcagaattt ttcattcagg
     2881 aaaagcagct tggacgtgca actcggacaa ttgtcaaaaa cgaaaaagga cattccctgt
     2941 ttttgatggt tggtcgctgg ggaacaaagg gcgatgcatt gtctctttat gccatgaatg
     3001 gcgatctcgt tgctcacatc aagcagataa gcctgacatt cggtacgcgt tttgagctgt
     3061 ataaagagtt cgaaaaggtg ggaaccatgc agaaaatatt caattggccc ggtgactttt
     3121 attatattcg tagacttcac tggacagtcc aaggtgatat ctataatcat caatatcaaa
     3181 tccatcattt caatcagcaa atcatgaaaa tggataaagc aacacttttt tcaggagatt
     3241 actatgtatt ggatgtctca aatgatgaag atgctccagt ttgtatttgt attgctgcgg
     3301 ttttagatta ctggctctac cgtaaagaca aaagtcgcga taagcctgtt tcttaccgac
     3361 ttaacttaag ttaaaaagat gtacctgaaa tgcggaaata cgcatttcag gtacatcttt
     3421 ttagatattc ttttgcatat gatcataaag atgaccactg atcatccgct gaccgacaac
     3481 tttgaagtca tggcgttcgt ataatttttt agcctttgga tttttttcat ccacacttag
     3541 accgatgacg gagcgattag ctttcttcgc caatttaggt aatgcttcta ataatcgcga
     3601 accgatgcct tgtcctctaa aatcttctga tacactgata gagtccaaat accattcgtt
     3661 gggaaacgtt tctttatcaa tgaacaaacg tgtagacgca tctagctgat atttctctaa
     3721 gataggtacc agtggctgat cgatgattga ttcttcttca tctgtataac cgtaagcaac
     3781 tcctgcaact ttaccgtcta tttcttctac gatacctcgt gaataactgt aacgataatt
     3841 tggatcagtg attgcttctt ctaaaatctc taaagtcttt tgttcccctg tctgcttcaa
     3901 aaatggcagt tccatatctt ttagaatcac taagatcaat ggggcgattt ctggagcatc
     3961 ttcttttctc gcaaaacgaa tcatagtttc ctctcctttt ctccattcta acatgcagaa
     4021 aaagaaatcg caaaatcgtt attttaaaaa atcttcaatc ttttcagtaa tgaaataacc
     4081 atgagtaacg attcttgccg cttcagttcg gcaataaggg cagacgactg gcatttcttt
     4141 atcattatgt tcgactacat tattgacttc ttcgtatgca aatttttttc cgcaattagg
     4201 gcatttcatt ttttccatgt tatctcaact tcctttcatc tttactctct tagcttactc
     4261 ttatattgta aaaaagagaa gcaatatcct tcttctatgc agatatccat acctgacggt
     4321 cctgttctcc atctattaat cggactttat aataaggacg ttcatctttg actagaagtg
     4381 tccactcttt cacttttgct tttttcccgt agtagctgac tgcttccttc atcgctgctt
     4441 gcggttgttt gaactcttcc gttttttcta tatcaaaaag atgttctgcg gccttttccg
     4501 tgtcatttcg tacggttgtt ttcccagtgg atggattgac tgctatgact tgtccttcac
     4561 aaaaaaactg gtattcatat gttgcattcg taggattctc caaatctttt tcaactgcaa
     4621 aatgaatagc agatatgtta tgttcttttg tttcgttttt tacgattgct gctgcttttt
     4681 tcaatgagat ccgatattcc tggtcactaa tatcatccat gtgaaaagcg gcattgagca
     4741 gtcccgtcat accggtaatc cctattacga tgagggcagc aacaccaaac atcatttttt
     4801 tcattcttca ttctcctgtt tctttttttt aaagaatatc aagaaatgaa cgaatgaaaa
     4861 atcgaatgaa acgaaaaaaa agtgacaatt ttgttatctt tattcgtgca gttctaatgg
     4921 caatccgtct ggatcaaaga aaaacgtcat ttttttcctg taaaggtatc ttctctaatc
     4981 ggttctgatt cgatccctaa ggactgcaat tctgcaattg tttcttcaat atcgtctact
     5041 ttgaaagcaa gatgacgcaa gccacaagct tctggatagt ttggtcgttg tggcgcatta
     5101 gcaattccaa aaatctccaa ttcagcactt cctagtttca gatctaattt atagtcatct
     5161 cgttctttgc ggtaattttc tctgattact tcaaatccta atttattaac ataaaaatca
     5221 cgtgatttct gataatctga aacaatgatg gctatatgat ggatcgttgt aaggttcata
     5281 tgagcactcc tattcttcgt ttaagctcgg atctatatta atctccagtt ccattgtaaa
     5341 tgtgtcagat tgaaaaaaat agctgttttt cctttttata agaaaaaagg caaaaaaaac
     5401 agaaagtagg tcctccaaga cactcttcct gttcccaata taataaatga aagtaagaaa
     5461 ttatattttc aagaaaacaa acagaaaatt atcataacac aaattattta taattgaaag
     5521 actagttttt tttcaagaaa agcatacaat agattgtgtt agtaaataca gaacacacta
     5581 catttagtgt cttaaggagt cctcatacat gaagtcatat tttcagtttt tagctcatca
     5641 gctaaaaggc tggccgcaac aaaattatta tcttttcttt ttcagtcttg gctgccaggt
     5701 catgactctt gtcaatagtc ccatcacttg gctgtccgtt attacattta tcggtaccac
     5761 gcttggtgta ttgtgtattt tatccatcaa tgcggcaaaa tcagtcaacg gtattttagg
     5821 tattttgtct gcgatttgtt ttattatcgt tgggttttca gcaaagaact atttaagtat
     5881 cggtgaacag attgcttata tgatcacatt ggatatcccc gtattgttaa gtaaagaatg
     5941 gaatcataat atggcttcaa aaatccgaaa attcactgga aaaagctggt ttatcgcaat
     6001 catcagtact ttccttgtct atcttgtttc aggattcctg attggtcgtt atacagatga
     6061 tcctcggccg tgggtagatg ccattgcttt ttctattagc ttgactgctg gtatcatcag
     6121 tttcttgcgt tacaacaacc aatattactg gtggttagct tcagggcttg ctcaaatggt
     6181 cctttggtat atttcattta cgcatggatc tgcaagtttg gcgatgttcg tgaacagctc
     6241 tgtttacttg ctgaatgatg tccttgcatt taccgtttca ccttggtata accaaaaaga
     6301 acgtgaacgt atgcaaaaaa tggaagaaga atactacaac gcacaacaac acgcataaaa
     6361 aaactgagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
     6421 cggcggaatc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
     6481 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctctattt
     6541 tttatagtaa ttccttcaga tactttcttg cctcatcatt gaaacgcagt gattcttcta
     6601 acttctgata atattccaac gcttgtttct gagcttcagt aaaacgataa tgttttcctt
     6661 tccatttgtc gattgtctct tgcacatttc cagattggat atctttcact actagttgcc
     6721 atttttcttt tgagactgta cggtctttct tatcagcaga ttgtatagct tctcgttctt
     6781 tacgcaatac ttttaaaaaa ccatttctga ctatccgagg aatgctgtcg aagaaccctt
     6841 ctgtaaaacc atagcgacaa tattgcttcc aaataaatag atagattttt ggttggatga
     6901 atcgttggtt tttcgcaaaa tattccatct gagcagtgac ttctggtgtt cgttgacgtt
     6961 ttgtctttct caacacggaa ataaatgttt caaaataagc attaggatgt actggcactt
     7021 cttcatatac gatggattgc caatctttac gtaaaaatgc gcgatagttg atcaagaatt
     7081 cttctacatc ctttactaat tcttctgcaa agtcgtcaaa tagttctttt tttatctgtc
     7141 gcttttttga ctgcccattg atgtgttcac ttattttctt gatttcattt tccaatgctt
     7201 gataatccgc tatgtaaatc ggcatttcta cttggcgaaa ttctgcgagc cgctgagcta
     7261 attttatatc cggtaaatat ggctgtttca tccgacgatt ttggtacaag acaaaacagt
     7321 atttttgcca tagtccttca ggaaaatcga tattcttctg cttaagccat aataattcgt
     7381 ctaaggccag atcaactttt gtcattccct gatggatcga agctgccact gtcggagaga
     7441 catgcaggtg atcggcaaag tggttgatgc ctagttttag gatctttccg gtttttggcg
     7501 atttaacgat gtattgcact tttaattctc taccacactc acaatacaat ttttgctggc
     7561 ttcgttttgt tcgaaaaaac ggattgatct tgaagtcaga aaacacccaa tctgttgcag
     7621 ctaaataatg ttcttccata aaacgagagc tgattagata tcggcggtgc ttatcgacta
     7681 gttcccgctg ttttttcgtt aattttgcat agatctccca acgttgactg cttgtgtatt
     7741 gtttagaaat tttgatggga tagcttttgc tgatttcttt tggaaaccat tcttcaaaga
     7801 cggattgcca ttcttccacg gctgtttctt tcctttctaa ttacaaaaag ctggctacta
     7861 acataacgtt agcaaccagc cagtgtttct tgctaaatta gtgagttgtt ccggcatttc
     7921 cggaaatatc ttctttattt tctactgctg cttcaactgc ataagtcaaa gaagaagcaa
     7981 tgtcttctaa agacatagaa ggcgtaccca ctggacgatc gatcacttga tcgggtgaga
     8041 atggcacgtg gatgaaccca cctcgaattg ccgggaattg tgtttcgatc aaatgaagca
     8101 aacgatacat gatatcattg cagacaaatg ttcctgctgt ataagagatg tacgctggta
     8161 gaccatgatc ttgtacattt tttgtcattg ctttgattgg caatgaggta aagtaagcgg
     8221 ctggaccgtt ttcttctaaa gccgtatcga atggctgatt tccttcatta tcagggattc
     8281 ttgcttctgc tagattgatt gcgacacgtt cgaacgagac tgctgaccgc ccacctgctt
     8341 gtccgacaca gatcacgaca tctggttggt gctgttggat ggcttctttg actacttgac
     8401 tgcttttttc gaatacggtc ggtacttcca ctttgatgat ttcagcaccg ctgatttcat
     8461 ctggcatttt ttttactgct tcataggctg gattcacttt gtccccacca aatggatcaa
     8521 aacctgttac tagtactttc atctgttgtt cctccgtccg attgatttaa catatggtta
     8581 tcttttatca taccattttc cttgaacagc gtaaataaag gaaacaatag tttaaataac
     8641 ataacagatc aaacttaata tattcttata aaaaaatagt gttccactac aatgttagaa
     8701 gaggttgcga caattattct gtcacaaccc ctctcttcta ttatttaaat agaatcatat
     8761 aagcaatttg gaaaactagc ataaataacg caataaacaa ctggtttttg atcactccgt
     8821 atttgtcttt catctccagc atcgctacag gcacgatatt gaagttagca gccatcggtg
     8881 tcagcagggt cccacaaaaa ccgcaagtca atgcaaccat tcctattaac gctggattcg
     8941 ctccatgact aaatacgaat ggtgcaccga tcccaaccgt catcacggtg atggccgcaa
     9001 atgcattccc catgattacc gtaaatatca ccatgccaag agcgtaaatg atgatgccga
     9061 tgttcacatt tccttctgga acgatcgtac ctactgcatt ggaaatcact gtcccaactc
     9121 cagcgcttgt aaataccgca cctagagaag ctaaaagcat tggcaacatg cttaacggcc
     9181 ctactgtgcc cagcatatct gctgcatcat ctaaaaatgt acttggtcga ttatctcgag
     9241 aaaagaacat caagattagc atggctgcaa aaacaccgac gcccacgccg actaaagcac
     9301 ctaaattggt aaatagagca aacaagatcg caaagacacc gatactcaaa gctggaataa
     9361 aaattttcat tcctagtttg tctgacattt tttccatata ttcttttgat ggaagccggc
     9421 tttctccttt gctgactttc ttagcaattg ctggtatggt catcgcaaag atcaagccac
     9481 cgttcacgat tgccggaagc catcttcctc ctgcaataac tacccctaag accgtccaga
     9541 aaaaggctga cccataacga tgaggattgg ttttatctgt taaatttctt actccagtgt
     9601 aaatcaatac gagtcccatc acgatataaa ggatctccag taatttatcg cctaataaaa
     9661 tatcaggatt tgtaaaaaag tccatcttat tgcccctttc ctggataata tttcttcgct
     9721 aatttctttt ctttaagata gaagtagaca cttgccacaa ctaaagccgt gatagccact
     9781 ggaacttcca ctaaagcaag ctgtcccaat gttacgtcat atcctagatc tttcagtgtt
     9841 gattggacta gcaacgcccc tgctcctccg atgaatagta cttggccaaa gaaccagcag
     9901 acattttcca tagctgaagc catacctttt agttcttctt catgcttagg atggacttct
     9961 aacccttttg attcgatggt ccccaatgcc atcggtaaaa tgattggacg aacaaatcca
    10021 gcaactccac caaaactcac gttaaaagcc gcaaagatca ttcgaaagat cccataaata
    10081 tctacaatca taccagcaga tactttcttg aatcgcttga tcaaggaagc cgctgattct
    10141 ttcagaccat ttctttcaag cgttcctgtt gccaacataa tgatgataaa aatcgccatc
    10201 ccgcgattgt ttacaaaact tgtacctaaa agttctaaca ttccttgaat gccaagaccg
    10261 ccagtcaaag ctgtaacaac taaagcaacc attacgatca atatcgagtc taatttaaat
    10321 gcaaacccga gaataacaat caagacgcct aaaaggctaa gataattttc catatatttt
    10381 cctccataaa atgacaatat ttttttaatt ataaagcaaa acacataaaa aatatagttg
    10441 ttttctcacg aaatagacac tatttttaaa tatttttcgt tattttttta tcacaaaaat
    10501 tatcttactt attgtaaggt aaagcttttt ttaatttatt gcccgataat atatagaaat
    10561 aaggtctagt tactgttttt tttaaatgat taataaataa caacttcttt ctatgaaatt
    10621 gcaaagcatt catcttcttt tccgctaacg atatatccgt cagtgcttgg tacactttac
    10681 taaaaagtat gagattgccg atatctggat aggtgtgcta tactacagaa aaagatatac
    10741 aatctgccac cgggtaggat aaagaggatg atcattccat taggtctttg aagggatgat
    10801 tttcctcttt ttgtgtattt ttttatagtt aaggaggaat gtaagtatgg catggatgga
    10861 attaatcata gcaggaattt tggaagtatt ctggtcaacg atgatgaaat ggagtgatgg
    10921 tttttctaaa atcaattatt ctttttacac agtgattggc atgattgcta gtttttactt
    10981 tttgtcaaag gcaatcaaaa gtttgccgat gagtctctct tatcctatct ggacagggat
    11041 tggcgcagtt ggttcggtca taattggtgt ggtcttgttt catgataagc tgaatctttc
    11101 cacttggttc tttgtgggga tgctactcat cagtatcatt ggcatcaaga ttactagcgg
    11161 ccactagaca cttggaataa gtactgatca gaaaaaataa gcctttttat ttaatattca
    11221 atttttttat gaaaaaataa gaaataagtc caatgaccta gcgacttctc cactcatcag
    11281 gtgtatgctt gtactatcta tagaaaagga gtgaatattt ttgaaaagtc tttcggtcca
    11341 agaattatcc aagaactttg gtcacaaaca agccctcagc gatgtcagtt ttagcttatc
    11401 ccctggcaaa atcgttggat tagtaggtcc taatggcgct ggaaaaacaa cgatcatgaa
    11461 agctatttta ggactgatcc attactcaga tggaacaatc tgtattggtg aaaatgagat
    11521 ttctccctct agtcataaag ggttggaaca agtaggagca ttgatcgaat acccgggtat
    11581 ctatccattc ttaacaggct atgatcatct gaagttattc tctgaaacca acgatgtatc
    11641 tgctatcgac actatcgtga atcagctcaa gatggaaaag tacattcaca aaaaagcgaa
    11701 atcctactcg ttgggaatga aacaaaaatt gggaattgct cttgccttac tgaaccatcc
    11761 gtctatcgtt attttagatg agccgatgaa cggtttggat ccacaagcaa caagagatgt
    11821 gcgaaaaatc attaccgact tggctactca gggcacctct ttcttgatct ccagtcactt
    11881 actcagcgag cttgaaaaaa tggtcgatga gctgatcctg atcaatcaag gaaagatcat
    11941 caaacaatgt acaatggctg aattgaacca aacagcgcaa gatttcatcg ttatctctac
    12001 aacaaatgat ctagctgctc gaacgatctt gacagaagct ggatatactt tggaagatcc
    12061 tgataaaatc aagcttttaa aagaaaacga agaattatta ggaaccgtga tccagctatt
    12121 gtctgcacaa aatatccatg tgacagacgt ccagcatctg acgaatgatt tggaatcttc
    12181 tctattggaa attctggatt cagtaaaggg ggaagaagaa aaatgacatt gcttgtaaaa
    12241 caagaattat ttaaattgat caagaaaaag tcaactgctg ttttatctgt tctattagtt
    12301 gttttgctca taggaacagc acttctagcc aaaaaataca cgacgatcat tgatccagtt
    12361 gaaatgactg ctcagctttt tagtgccaca tcttggattg tctttatcat gattgcagct
    12421 gcaagcacga tcatttcgat ggaagcacaa tatggtacat tgaaaaatct cctttatcga
    12481 aagtattctc gaggagaaat attagtaagc aaatggatca cattagttat ttattctgtt
    12541 tatttatacc ttttagctat tattgtcact gtgttgatga aactgattct tttcccttcg
    12601 atttccttca cggagaaggt ttctactggt caaacactga tccaaagctt gttcacttat
    12661 actttgggta gttatatcgg tttatggctg attttaagtt tagtgttgat gattgcttgc
    12721 tttatcaata gttccggcgc atccatctca gcaggaatcg tcttttattt tgcttcgtca
    12781 atcatatctg gtatccttat tgcactcatc caaaaatggg agtggatcaa atggaatccg
    12841 atcagtatgt tgaatctgca aaaccaaatt ggaaacgaag agatcatgaa gcaattgact
    12901 catctttcta ctaatcaaat gctattcggt aatttagctt acatcgtttt gttcttagca
    12961 ttaggatatc tcgtatttaa gcgaaaaaat gtatgatgac tcatcaaaaa agaggctgtg
    13021 aaagagacgt tcagccttat tgccgattgg ctgtctctta aacaccgttt attctgaaaa
    13081 aggagctgtg acaacatttg tgtcacagct cctttcctag tatgtttttg aataaacgac
    13141 aggctcacaa cctctcttta tacttctttt atacttctat acgtgaagca tcccagtggc
    13201 aaataaaacc attgcaatca ctccgaccat cgtcacacct ataagtaaaa tcttatctaa
    13261 gtggatatgt tgtacaggct cgttttgctc cttacgtgct ttgaggtaaa aataaatgcc
    13321 tggcaagaaa agaacaagaa caagcattac ttcattaaag gctacgacta gcatagccca
    13381 tacttgaaag gcacttgcta aaagccctac taaaaattgg acccattctt tccgctgata
    13441 agaaagtttc atttggtaca atcctaagaa aagccacgtg aagaaaatag ctgctgtacc
    13501 aagtgtgtaa gcaaagttat aagcactgtc agtgaataat aatgaaagta aaaagacatt
    13561 cgtacataac gtcgtcaata cgatagcata agttggtgcc ccatttttgt tgagttttcc
    13621 ccatgcttta ggcaaaagtc cgtcttcagc catgtttccc attgtttcaa tcggtaagat
    13681 cgtccatgag agccaaacac caactaaaga aatgatcaaa ccgccgttga tcacgactgc
    13741 tccccattta ccaaccatca tttcaaacac atagcccata gcaggctgcg ccttgatcgt
    13801 ttgcagctga ttcatcgtca ttgtcccata tggaagcatg gaaaccaaga cgtaaataat
    13861 aatcaagccg aatatcccta gaatcgttgc tttcccaaca tctgattgtt tttttgctcg
    13921 tgaacctacg acagaggctc cttcaatacc aacaaatacc caaagcatca ccatgatgca
    13981 actcaatact tgactggaaa acgggatcgg ctgtccattc gcattcaata taatgtcgct
    14041 agaaaagtta tcaatgaatt gttggatcga aaacgtgctg atagctacta caataaataa
    14101 aaataatggc actaatttac agaatgtgac gatagcattg acgaaactag cattttcgac
    14161 tccccgattc actagccatg catatcccca taaaaagact gtactcatca cgatcgatgc
    14221 cagattttgc ccaccttcaa atactgggaa gaaatatcct aatgcgctca tcaacaatgt
    14281 tgcaaaagct acgttgccta accagcatgt gagccagtaa ccccaaccgc tgataaaacc
    14341 agcgaaacgg ccaaaacctt cttctgcgta actaaagatc ccgcctttta aatctggacg
    14401 ttttttattg atattattga tcgacaagga gagcatcaac attgctgttc ctacgagtac
    14461 ccaactgaaa atagctgggc cgccagccga tccggagatg tccgtcataa taccaaatac
    14521 gccacctcca atcgctgaac caattactaa ggcagcaagt ggaattaaac caattccttt
    14581 tttctgttgc tctgtatcca tgtaagcatc ctccaaaata aaaccgcttt tatcaaaaag
    14641 tataacaaac cttttttatt tttacttaat taataaaaac tttaatagaa atataattct
    14701 accggctttt ttctcattat acaagcaaag cgcctagtcc ctttccaaat tacaccacca
    14761 aaaaacttaa aaaagatgct atactaaaag gaaagaattg gaggatgatc catgaacatt
    14821 ttatatatat cgatttcagg aaatacgcgt gcctttgcca aacatctagc agaatatgct
    14881 gaaaaaatgc atgcagaaga tcctgtcaat cctgaagtta ctttaaaaga aatccatgaa
    14941 aatagtgatt ttacgaaaga aacagaacca ttttttactt tcgttcctac ttatttagac
    15001 ggcggaaatg gtttagataa cggtgataca gaaatcttga ccgaaacgat gcgtgaatat
    15061 ctggaacatg aagacaatca taaactttgt cttggtgtag tcggtagcgg aaataaaaac
    15121 ttcaataatc agtattgtct aacagccaaa caatatgcac aaacatttgg ctttcctttc
    15181 ttggcagatt atgaattacg gggaacacca tctgatgtga cacgaattta tcagatttta
    15241 gcagaaaaca ataaataata aaaaagaaga agctgaaaaa tagatttcag tttcttcttt
    15301 cgtttctatt gtttctatca tattaagctt tgacatccat cacaggtgct tttgcttttg
    15361 ctttacctgt tttttccaag acaaagtttt ttacacgatc catattggtt accaagacga
    15421 tcatggatgt ttctttgcct gctgctttga tcgcttctaa gtcagcttct gctacaagcg
    15481 tatcaggtgt cacttgctgc ccttctgtta ctttcacatc aaatggcgta ccgcctaagt
    15541 caactgtgtt gattcccata tgaagcaaga tttctaaacc atttggcgtt gtgatcccaa
    15601 tagcgtgttt cgttgggaag acagagctga ctaccccagt aactggagaa tagatatgtc
    15661 cgttttctgg ttctacaaag tagccttcac ccatcatctt ttgtgcaaaa actggatcac
    15721 ttgctttatc taaagaaaca actgttccgt cagcaactga tgagaggata gtcacacttt
    15781 cagctgaagt ttgaggtact actttttcag gcacttcatt tactgtggct gtttcagtcg
    15841 ctaattcttc tttttctaaa cggtctttag gaataccgaa gaagaatgta gcaacgaagc
    15901 caccagcata agctgccaat aatccaagga tgtagcctaa ccatttaccg tcagagatca
    15961 atgggatcaa agcggctcct gaaggtccaa tagcgatagc cccgacattt ccgatcattc
    16021 cgatcactgc cccgccgata cctccaccga tacaagcagt aataaatggg cgtcctagag
    16081 gtaatgttac tccgtaaatc aatggttcgc cgattcctag gatcccgact ggtaaagctc
    16141 ctttgatcat ttctgttaat tctttatctt ttttgcagcg aatccataat gccaatgctg
    16201 cacccacttg tcctgcacca gccatcgcaa gaattggaag caatagcgta cgaccagttt
    16261 catcaatcat ttgcacatgg attggagtca aaatttgatg cagtccgaac ataaccatcg
    16321 gcaagaataa tgtgcctaga acgaagccgg caaatgctcc accaacgcca agtacccagt
    16381 tgatcccacc gaccatgcca tcagaaatga aacctgctaa aggcatgatg aagaaaattt
    16441 caatcagacc gatggcaatc aatgaaagag ttggtgtaac gatgatatct accgcatcag
    16501 gtactacttt atgcagtttt ttctcaacga ttgacaatag ccaaacagcg aagatgacac
    16561 ctaggatccc accttgtcca gctgcaagag cttcaccagt aaataagttt ttcagtggtg
    16621 cttccggatt catccctgtc agcatcacaa cggccccgat aactccacca agagttggtg
    16681 ttgcaccaaa aacttgtgca gcattgatac ctgtatagat aactaggtag ctaaacatcc
    16741 cgtttttcaa gatgttcatc acatcgatat attgttgcca tgttgctgca tcaagtgttc
    16801 cggctgtgac taagtttgct aaaactgcgg caatccctgc cacgatccca gtaccgacaa
    16861 atgcaggaat cattggcaca aagatattag aaatgtcttt taataccgat ttgattttag
    16921 atggtttttg tttcgatttt tgtgccgctt tcatttcttg tgcccgttcg tttacacggt
    16981 cttttccaga tgctgatgaa tttgctgtag ctgtacttac agaagaaagt ttttctccta
    17041 atttcacgcc tgccaaatca accatttgct gtgctacttt gttcactttc ccaggtccga
    17101 tgatgacttg aagctgttca tcttctacta caccaagcac tcctggaatc gcttttaatt
    17161 cagagacatt tacaagatca tcattgatga tcttcatacg cacacgagtc atgcagtgga
    17221 caatgctttc tacattgccc atgccgcctg cccctttata aatttgtttt gccagttctt
    17281 ccaaagtcag ttcgtttttt gccatggtct tttccccctc ataaggtccc ttttacaaat
    17341 ccgtttgctt cagctaattt tgcttgagct tcctctttat cactatttgt caaaatcatg
    17401 acgatagcca gcttaacatt ttgatctgct tcttcaaagt acttttcagc tgtttcgtaa
    17461 tcagcttctg tcgcttgcat gatgattcgt tttgagcgtt cgattagttt ttcatttgtt
    17521 ggtttgacat cgaccatcaa gttattgaat actttaccta taccaatcat actgatagta
    17581 gaaatcatat tcaagataag tttttgtgct gttcctgact tcaatcgagt agagcctgtc
    17641 aaaaattctg gacctgcatc gacttcgatt gggaaatccg cgtgtttact gatttcggct
    17701 tgtttattgc aagaaatcgt tcctgtgaca gcaccgatcg attttgcgta atctaatcca
    17761 ccgatcacat atggtgtacg accgctagct gcgataccaa taactatatc attttttgtc
    17821 aaattcagct tgattagatc ttcttgccct agctcataag aatcttcggc cccttcgaca
    17881 gctacagtca ttgcttcttc tccaccagca attagaccta tgaccatttc cggttctaca
    17941 ccgaatgtcg gtacgcattc agcagcatct aacacaccta gtcttccact tgttccggct
    18001 cccatataaa tcagacgtcc acctttttta aaggactcaa tcgtgttagc aatcactggt
    18061 tcgatacttg tcagttcttt ttcaaccgca gcggccactt tctgatcttc tttgttcatt
    18121 agttgaacgg cttgagaaat actcatctca tctaatccaa aagtttcttg gtttctgcgt
    18181 tccgttgtta ggttctctaa attgattttg ctcattttta tcttccttct tttcttataa
    18241 attgatagtt cataccagct ttgatttggt tgatcaatgg tagctcttct ttgataactt
    18301 tagctactac attcactttt tcatccgctg gcaaatcata tttggttaat tggatctcac
    18361 ccatatagcg caaatacttt tcgttatcta aagtaataga ccctttcata cgcgtagctg
    18421 tatttcttgc tgggataggc ggaatctctc gaaaacgtgc atctacgctt cgtatgacat
    18481 ctcttgcatc gtcttgccga ttcgtatgct tccctaatat atattcgtaa aattcttcat
    18541 ctacaggttc cgtatggagc aagactgtct gttctttttg gaaagaagca aattgctcct
    18601 gaacgttttc tgacagacct gcatctccga tgtaaacaat atccgtgtta cttgctaata
    18661 gatctagagc gcctgcaaga ggatggatcc ctcgatgttc ttccaaagtt ggcaatcctt
    18721 gatatagtgg gcctctcaac tctgtatctc ctggtacaaa accttggaca aggagacctt
    18781 gaattttgag ccattgattt tttttctgat accattcttt gtccagccct gtttcgggac
    18841 gtggataata attatgccaa gcttcaatct gtgagaaatc agcttctgct tctttcaatt
    18901 catcgatatc tttaggcgtg atcgtgctag cattcaaact gattttcaat tgatgtgacc
    18961 agtcggcaat ctgctgattg gaaatatgat aatccattct taaacctgtt acaccaattg
    19021 ctttcaaagg cgttagatct tctaatgaaa aacccgctcg ttccaatgcc tctcctgaaa
    19081 tatcgaccat caattctagt ttattctttt tcgcttcgct tcctagttcg atcaatcgct
    19141 tttgatatgc cgaaacatca tcttctggta tatgcatgga agtgaaaata ccgacaaagc
    19201 cattggatgc catttggcgg atatactgtt tcttctcttc tgacaaagaa tcgttcataa
    19261 atattgaaaa gccaaacata ttatccctct ttttctgtat ccgtcttcat ttctatgact
    19321 agagtatata tctaaagaaa caaaatttca atacttttat taaaataatt aaatttcatt
    19381 tctaaaggtt gagtttatat tatcaaaaga attgtcataa cctaaaaaag gcactgctaa
    19441 gcaaaagcag tgccttgaaa tattttattt aaataacaca aaaacataat tactcataag
    19501 aaaccaattc tgtattatct accatgaatg taaagaaccc ctcattaggc atcggatgaa
    19561 aataagcatt gatcactctt atcaaggcat tatggcaaac taacagatag acattttctt
    19621 cgtcttcgat gcattctttc aataaaggaa cgatccgtgc atacacatct aagactgact
    19681 ccccatttgg gaatcgtaca gcgaacgcta aacgtgcttt ttgaaagttc tcatctttgc
    19741 ttggcagtcc atcataatcc ccaaaatcca tttctaccaa tcgttcatca acggtcagcg
    19801 gcaagctgag acgatcagca actgcttgtg ctgtatctct tgctcgttga agaggggaat
    19861 ggatgatttt cgtgattgga acaggcaaat ctactacctt ttctgctagt ttctgtgcct
    19921 gcatctgtcc tttttcagtc agcggcacat ctgcccgtcc gcaaactaat ccttgtgcgt
    19981 tccaagttgt ttctccgtgt ctcgttacat aaagcatgtg attctctcct tcgttggcaa
    20041 agttcccctt aaccatacct tgttgttctt gagattacaa gggttagatt ctctcaagag
    20101 aaataatctc agtagatact ttatccagga aggtttgatc atgttccact agtaacatgg
    20161 caggtttcac gttcaagatc agttgttcta attgttcttg attgaagaca tccaaataat
    20221 tcaatggttc atcccatgta tatagttcag ctggctgtga taaagattta gccaattcca
    20281 cttttttccg ttggcccata ctcatctgct cgatcttgtt atgaaaaaca tctctttcca
    20341 tcccaagctt tcggaggttg ttcaaaaatg cttggtagtc tacttggttt ttctctgcaa
    20401 attccgccaa cgttcctcga ttgtcttcat aattttggct tgcataacta atgctcagat
    20461 gttttggctg gtatttttct cctataacct tgccgttgaa tgcccccaga agataatgga
    20521 taatggatga ctttcctgca ccgttaggac ctgaaatcgc cacccgctga tgaggctcga
    20581 ttgtaaaatg aattggctcg aataacagat tttcataccc taattgaaga tcttctacgc
    20641 ttaaaagtcg cttatggtga gacgcttggc tattcatcgt caaagaatcg atatattcga
    20701 tatcttttaa tagtttttct ttctcgctga tctgggtctc catccgattc acgattgctt
    20761 tggatcgttt catcgtccgt gcagcatcag cacccactgc tcctttattc actcgtctag
    20821 attcagtatc gatgaatccg acttgtttct ttgttttatc tccttctcgg gaacgagacc
    20881 attcggcttt ttcagctgct gttttcttta gcctactgac ttcttttttc aatttttcat
    20941 tttgagccat ttcaaattca tcacgaagtt ttttctgttc ttcatagata gagaaattcc
    21001 cttgataaag ttccagttga cttttttcga ttgctaaaac atggtccact acttcatcga
    21061 taaatccccg gtcatggctg accacgatga agccttgttt tttctttttc aaataagccg
    21121 ctacttgttt tctaccagag atatccaaat gattcgttgg ttcatcgatt aacgggaaat
    21181 gagtgtcatc cacaaataaa agtgccagta ggacttttgt cttctctccc cccgatagtg
    21241 tgctgaattc tctccataag atttcaggat ctgtttgcat caattggagc tctctttcga
    21301 tttcccatat ctcaaaatcc gtaatatcat ttaacacgta ataggttaaa cgttctttat
    21361 cttttgtctg ttgcgggaaa taggcaaatt cttgctgatg gattacttgc ccttgataag
    21421 gtagtttgtt ttgtagaata ttcagtaaag ttgtctttcc tcgaccgttt cgtccgataa
    21481 gtcctagttt ccattgtgtg tcaaaattta gatttgcttg ttcaaataat aatgtgcctt
    21541 ggctgtcgta gccgaatgtc agatttttta tttcgatttt agacattttc catcacctcg
    21601 taaaaaaaga ccagtcctat tttcagaact ggctaaagag gatgcaaggg ttggatacac
    21661 acaaaaagac ccatacatcg aaaaaaccaa gccaatcccg aaaatctgca cactgcttcc
    21721 ttgtctccac aaggtacagt ctgaatgcag ctttcatcaa tcgacttaat ttttcaatgc
    21781 acggatccct cactttgtcc tatatttgaa attacgatag cataaagaaa atgattttgt
    21841 caactacttc gggaggatgg tgaaaaatct gctaagtgtc tgtcctaaga tttttgtttt
    21901 ttctaatgtt tgcctgtgtt ccattgcttc ttctaaacct attggaccca aatgaatact
    21961 taagacaatt gggagaaaat cagaaagtcc ttctagctct tggtctctac ttccgcaaat
    22021 agcgattatt ggttttcgat atttttttgc aagcactgct acaccgtatg gaacttttcc
    22081 gtggatcgtt tgctgatcga tccgcccttc tcctgtaatg atgacatctg cttgttcgat
    22141 ctttttttcc aatccagtga tttggctgac taaatcgaaa ccagaaacca tcttcgctcc
    22201 caacaaaaaa agggctccac caataccgcc tgctgctcca cttcctggaa tatcatctaa
    22261 atccacctcc cagaaatctt ttatttgctg agcaatcttt cctgcttgtt tatctaagaa
    22321 agctagcgtc gtatctattc ctcctttttg tcttccaaat tgccaagcag ctccttgttg
    22381 acctgtatat ggattggtaa catctgcagc gataatcaat tttactttag aaacaagaac
    22441 gtttcttcga tcaaaatgaa gttttttagt agataataaa ggatttcctt ctgtgtaccc
    22501 ttctaaagaa gcacccaagg attggagtaa tcctagacca ccatcgctac acccgcttcc
    22561 tcctaaagtg acaataattt gttctacttc ttgaagcagt gcatctttaa taagttctcc
    22621 taaggcataa ctggaagcaa gtcggatagt ttgatccgtt ggtttatcaa gtagatctaa
    22681 ccccaatgct tgtgcagatt cgatgactgc ggtgtttttt ccttgccaag ttgtcaataa
    22741 atagctgatt tttcgctgac ggaataagag atccatccca tcaatggtac gccatgttcc
    22801 cctgagcgcg taatagattg cttctgcagt attttctccg ccatctgcaa tcggcacatt
    22861 gatttttctt cctttacgat cttcccagcc atttagaact gcctgattta gttcaaatga
    22921 agaagcactt cctttaaatg aatcaattgc cgccaaaata tccatctgta tccctcactt
    22981 tcttcttaag taagacactt tttttcattt ttttcaaaca aaacaatgct attttcttcc
    23041 atttttctat atactaaaag ggaactcatt gaataaagga gagaaaaaac atgaaaatcg
    23101 caatagctgg ggccggagca atgggcagcc gaatcggatt gatgctacat caaagcggaa
    23161 atgaggtcct cttgatcgat cgttggcctg ctcacattga agccattcgt acaaatgggt
    23221 tgattgctga ctttaacggt aaagaagtgg tcgcaaaact gccaatctat tcaccagaag
    23281 aaatcatcga aagcaacgaa cacgtggact tgatcgtagc attaacaaaa gccaatcaat
    23341 tagatgatat gttttgttcg atccaatcca ttattactga caatacttat gttttgtgtt
    23401 tactaaatgg attaggtcat gaagatgtac tggaaaaata tgtgccaaag aaaaatatct
    23461 tatttgggat cacgatgtgg acagctggtc tagctggtcc cggaaaagtc acattgttag
    23521 gtgatggaga aatcgaacta gagaacttgg aaccagaagg cgaagcattt acaaaaaaag
    23581 ttgtagaagt ctttcaagaa gcaaatttaa atccgatcta tagccataac gttcgttatt
    23641 ccatttggcg aaaagcttgt gtaaatggaa cattgaatgg tttatgcacg attttggatt
    23701 gtaatattgc tgaactaggc gcgcaaaaag cggcagagag catggttcga acaatcgtat
    23761 ctgaatttgc ttctatcgca gcaaaagaag gaatcatact agatcaagaa gaagtgtacc
    23821 aacatattgc ttctacttat gatcctgaca acatcgggtt gcattaccca tctatgtacc
    23881 aagacctgat caaaaaccat cgtttgactg aaatcgacta catcaatggt gccatttggc
    23941 gaaaaggaca aaaatatgat attgctacac catattgtgc ctttttgacc caattagtcc
    24001 atgcaaaaga aggaatcctt ggcgcagaat aaaaggctct ctgatgagaa tcagctgaat
    24061 cagcagctgg ttctcttttt ttaagcccaa taaaagatca aaaagaaaac acaactctca
    24121 tgatgccata agaattgtgc ttgtttgttt cagtacataa tctcttcaaa atgtaggttt
    24181 tttatttgtt ttcaacagag gagaggtcat attcgtattg ctcataaata gtggaatcgt
    24241 tagtgataaa tcgttttgcc caattttctg catcataaaa ttccaatagc tctgatagga
    24301 ttggcttaaa tggtgtatgc agaaattccg gtaattcatc taaatcacgt tctcgaagca
    24361 aaaaaatatt ttcaggacga taaaaatgat aatgagcaat cgcttgatta tccgtcacta
    24421 gtttcttttg aaaatacatg gattcaaatg tccgcaaagt cactccttgc tgaccctccc
    24481 gcaacagttc cagaatcccg cgcgattccc ctgttttttt caggtactct tcataagtaa
    24541 gatatccagg ttgttcattc cctcgatgtg gaagaatgaa atagttggtc gtaacatctc
    24601 tttttataaa ttcctgctta tagctttctg ctcgttcttt tctcccatta ttcgttgcac
    24661 caaaaaatag atccgtcttt ggttcgctag aagaaaaatt catatgtttc gaataaaatg
    24721 aactattatg tttcagccca agttcttttg cttccaaaaa atcaaaatga taaatctcat
    24781 cgattgccgg ttcatcttgt gcctgcttca gcatcgcctc gtgttctgct ttgaagtgat
    24841 tccaaaaaaa taacacaatt tttgcattgg taaatgggcg cacgcgtcga gccatctcca
    24901 tatcaaatcc ataatctaaa aaaacgatca gctgataatt tgccaactgt tgtctagctg
    24961 atttaatgaa ttccgactgt agtaaatctt ttccggacca aacatctaaa gagcggatgg
    25021 aaggcaaaaa ataaagtgat ttattttttg caactagcag tacgtcattt ttgttcatct
    25081 tttccgcctc actttctctg tcactttttc ctatgatagc ctgtttaaat agtaaaaagc
    25141 cagtaaaacg tttcctatat ttgtatgaaa atttaacatt tgtatgaaaa tatgatgaaa
    25201 taaatcattc ttctattaaa attcgcctaa aagttttctg aatagttgta attgtctgaa
    25261 aatttgttat cattagtcat tgttaaatat tgctatttat tcttaatata aattttgatt
    25321 gtgaatttaa aagaaagagg tcatttatgg aagataaaaa attgaaaaaa caacttagct
    25381 ccagacatat caccatgtta gctttaggtg gagcaatcgg tgcaggtcta tttaaaggaa
    25441 gtggcgaagc gattgggatc gccggccctt ctgtattgat tgcttttttg attggtgggc
    25501 tgattttata tatcgtgatg aaaggtctgg gaaaaatcgt tttaagcggt ggcgacacgc
    25561 atcacggatt atctggtttg atacgccctt atctaggtgc tcattctgct gattttactg
    25621 attgggtcta ctggtctatg tggattatca atatcatcgc tgaagctgtt gcagctgctt
    25681 cctttttgca gttgtggttc ccgcacattc cagcctgggt atttgttttt atgttggctg
    25741 ttttaactac gatcatcaat ctttattcgg tacggttatt cgcagaaaca gaatattggc
    25801 tggcttttgc taaaatcagt gtcattatct tactgatcat ttttgctact tatcttgtcg
    25861 gtcagcaaat gttgggcaca ggcgttttcc ctacccttca gcaattgact gaccatggtg
    25921 ggtttactcc tcatggtatg aagggaatca tcagttcttt gcttgtagtt atctattctt
    25981 acggcggttc tgaactgatt gctatcacgg taagcgaagc agatgatcct aaacgtgcga
    26041 ttcctaaagc aatcaaaggt gtcatgggaa gaatcatttc cttttacatc attcctttgt
    26101 ttttgctttt gattcttttt ccttggaata ctttagcagg cacgaatgtc agtccttttg
    26161 tgatggtatt tgaaaaaatg aatatcccat ttgcagcgga tatcgtcaat tttgtgattg
    26221 tccttgcttt gttctcatct atcaattcgg gtgtgtatgc atcttcaaga attttgttct
    26281 tccgtttgaa ggatcgaaaa ggttcctcta gaaaactagc tgttttaaac aagcatcaag
    26341 taccgcaacg tgctgtttta ttttgtacca gtgttcttta tcttggtgta gctctttctt
    26401 attttgtcgg tgacaaatta tttggctatc tggcaggttc cctttcgtat acagtattat
    26461 tgatctggat cattatcagt gcggcatcct ttgtactggc actaagaaaa ggaacattat
    26521 gggataaagg aatcagcttt tttgcattag ctgtcttagg attgattttc cttggtatcc
    26581 tgttcacgaa ctccattggg gtaactgtat tgactggcct gctttacctg ttcatttatt
    26641 tcagttatca aaaaaagaat gatgcgttcg tattgacgaa tgaatgaaat cgatagaaaa
    26701 ttttatttta tttatgtgga atagatggag ctattgaaga aaggagttgt gacaaaagtc
    26761 ttgttgcaac tcctttttcc gaataaacag tctcatgacc tcttggtaaa cggtgttcaa
    26821 aaaccctctg tgcaaaataa ttgattgttc tccatgctca tgacatgata gaagaaagga
    26881 atgaaaaaaa ggagtttgtt ttaaatgaaa aagtattgga agtttttgtt gatgatcggt
    26941 gtttcaacgg tagttatgtt tggtatgatg tacttgaatg tctatgcgct cgatcatatc
    27001 ttcttcagtc gtacacgagt attcatggcg ttgatgatgg gtgcagtcat ggcagtcatc
    27061 atgctgttgt tcatgtggaa aatgtatgaa aacaaaaaga taaatgttat gatcttagcc
    27121 gctagtcttc ttgtttttgc cggttccttg tttatggtac gaagccaaac tactgtcaac
    27181 gacacagctt ggatgaaggc catgattcct catcattcta tcgctatcct ggcaagtaaa
    27241 cgagctgatt taaaagatcc tgaagtaaaa aaattagcgg aagaaatcat tcaggcacaa
    27301 gaagaagaga tcgacaaaat gaaaaaaatg atcaaagaaa tggaatgacc attatccgtc
    27361 caaataaaaa aagaggatgt tccagaagtt atcagcttca agaaataaga agaagctact
    27421 tctggaacgc cgtgaataag gggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    27481 gccaaacaaa aatagcttct cctatttttc gtttggttag gcttattacc gcagatgcaa
    27541 gcttttgaac accgtttatt aagaggttgt aaaatcagcg ttctgacctg agtattagag
    27601 agacaaatgg aaaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca
    27661 gctgattgaa caccgtttat cgagaggttg tgaaaaagtc gcttagtttc gcgtattaag
    27721 aaaaattttg tgaaatggct ttccacattt ttgtataaat ttggcttaat accgagaaac
    27781 tggcttttga ataccgttta ttcgtaaaag ggattgtgac aaaagtcttg tcacaatccc
    27841 tttttatgtt tttattgttc taattgcgct gtcttgctta ctgcttcttg cggtttcaca
    27901 aatttttttg agattcccca acctgtgaag gcactgacca tcgaaaacac aggagaaagc
    27961 aaactgaaaa atacgaatgg caagtaagtg agtgtaggaa taccaaatgt acttgctacg
    28021 aaacttccgg caattcccca aggcactaag tagttgatta ctgttccacc atcttctagc
    28081 gttctaccta atacagttgg atcaaatcct gctttttcat aagtttcttt aaatgcatta
    28141 ccaggcagaa taacagatag gaattgttca ccaataaaaa tatttactcc gatacttgtc
    28201 atcaatgttg taaaaatcaa atttggtgtg ttcgtcatct ttcttgatac tcgttccatc
    28261 acggttgaga tcaagccaaa ttcgatcaac aatccaccta atgacaaagt tagaataatc
    28321 aatgacacag taggcatcat actttcgatt cctccgcggc taagcagtga atcgatttgt
    28381 tggtttccag tatttgaaac aaaccctgat tcgatgaccc cagccaactt cgttaaggaa
    28441 gtttgtgggt tttgaataaa aatcattcct actgctacag cgatattcaa caaaatcgtt
    28501 aaaattgccg gcaccttttt ccatgcacac agtaacatta aaaataaagg aatcagtgac
    28561 cagattgaaa tagtaaagtt tgcttctaga acatcagtca cttcacgaat agatgaaaga
    28621 cttgcggctt tacttgtgtg tcctaaaatc atgaataaaa agaaagaaac aacaaatgcc
    28681 gggacagttg accacatcat atgcttgatg tgtttgaaca aatcggcatc aacaatagct
    28741 gctgctagat ttgttgattc ggataatgga gacatcttat ctccaaaaac ggcacctgaa
    28801 acaatagctc caacaaccag cgctggattt aagcctagtg ttgtcccaat accgaaaaat
    28861 gcaatcccaa tcgttgacat aacagtaaag gcactcccta cagcgctacc tacgattgca
    28921 cacacaacaa atacagaagg gacaaaccac tggacactga tcaatttgaa cccaatgacc
    28981 attagagttg gaatgatccc tgcttgtatc catacagcaa tcaatgaacc gactaaaata
    29041 aaaataaaga ttgggatgat tcctggtttg atgccattga tgattccttc gtgcagccaa
    29101 tctgtcgggt atctttttat cactgcatac aacatgacca ttccgatcgc tgctaagatc
    29161 gtgatattag gtgagacctt taatccgaca acgccaatcg caatgcctaa aacaataacc
    29221 attaatacaa gtgttgcttc taaaaaactt ggtgttcctt tttttcccat gataatctct
    29281 ccttttttag ttgttcttat gttctaaaaa agttaagata tcggattact ccgccgcaat
    29341 tcatccgcga ttcctccttt ataaaaataa aaagacctgt tttaaactaa ggacgaatga
    29401 ctccgcggta ccaccttaat taaaaacaga tctgtttttc actttcaaac ttttattcaa
    29461 atgtatggac tttccatgta attcgtcaat taggcttgat cggttcacag cgaccaccga
    29521 ctttctgaac aaaacaccta accgctactg cgtgaaaagt tgacttgtac gaagtttacc
    29581 ttccataaga tcatttgtca atgaaaaaga aaatattttt tcatttttct gaaaattatt
    29641 tttataactt tcacacacaa gtttattttt tactagaaag tagcgccctc ttgttttttt
    29701 cttgctacta tttcttgatg ttcttgcttg attctttcta atagctttgg ctctttcaac
    29761 agatcaagag ctgtattggc gagtagttct gctgcaatcg caatagaagc aaggcctttg
    29821 tcacttttag cagcagcttt gaattcttct gtgtgtccgg caatatatgt ctcagagatt
    29881 gctaccgtag gctggattgt tggtatgact tggctgacat ttcctacatc agaagaaccg
    29941 agacttgttc tttgttccgt ttctatttct tcatctggaa cacctgcttc ttttgcatgc
    30001 tggaagaata agtcatcaaa agaaggagta acgatgacat catcaactgc attttggaac
    30061 aatccaaact caaaagtcgt gcccgtactt atcgcagcac ctcgtacgat attttccact
    30121 ttttcatata ctttatctaa tgtttgccga tttcctgcac gtaaatagaa acgtccagca
    30181 gcgtaatctg gaatgacgtt ggcagctact cctccgtctg taatgatccc atggatattg
    30241 acatcttttg gcaattgcaa gcgtagagcg ttgattccat taaacacttg gatcaatgct
    30301 tccaaagcat ttactccttt ttcaggtgct gctgctgcat gggaagcgac accgtaaaat
    30361 ttgatgtcga ctggatcatt cgctaaagat tctgtcgttt tcccataacg aaaagctgga
    30421 tggacgcata acgctacatc gacatcctca aaaaaacctt ctcgaacaaa gctgccttta
    30481 gctgatccgt tctcgccccc ttcttcccct ggggtgccat atacacggat ttctccacca
    30541 gtttcatcaa tgaattgctt cactatgctg gcggctaata cggagtaagt accaaacaaa
    30601 ttatgcccgc atgcatgacc aatacctggt aaagcatcga attctgccaa aaaggcaatt
    30661 gtgggaccgg gtttattgga aatataacgt gcatcaaagg ctgttcggtg tccagctact
    30721 tctttttcta cccaaaacct ttctttttct aattgtttaa tcaacgctgc tgaggaataa
    30781 aactcatagt tacttacttc aggatgttcg tggatatcta gagcaagtgc ttgatattct
    30841 ggtaaacgat attggattag atccttcaat tggtttgttg agattgttgt tgtcataaaa
    30901 aattcctcct atgctagtca tttttcttat tttctcccga atgtttccca tgcaggcacg
    30961 cttgatcctt ttgatgtttt ctcgattact ttgactgtgt cttctgtttg ataagcgtct
    31021 actatttttt gatacgtttt attgttttca tcttcttttc ttgcaacgat gatattcaca
    31081 taaggacgtg catggtcatc cactggttct aagaagatgg catcagaagc aggattaaat
    31141 ccagcatcta cagctacacc gctattgatc actgaaatgt ctacatctga caaagcacgt
    31201 gctgtttggg aagcatctaa ttcagaaatg tctagatttt ttctattctc ggtaatatca
    31261 gaaacagtgg gcgcttgtcc ttttgcctta tccactttga tcaatccagc agtttgcaat
    31321 aacagaagag ctctgccgcc atttgtaaca tcattaggga ttgctacttt tgctccgtct
    31381 ttgatatcag ctacatcctt caaagtgtta gaataaattc ccagcggtgc attgacagta
    31441 tttccgatcg atactaaatc agttccgtgt tctttattgt aattgtctaa aaagaattga
    31501 tgttggaaag aattcaaatc aatcgatcca tctgctaaag ccacatttgg ttgattgtaa
    31561 tctgtaaatt tcacgtattc caaattaatg ttctcctttt tcaaacggtc tttcacgttg
    31621 tcccatacat ctgtatcttc tccaataatc cctagtttta cgatagtttc ttttttgtca
    31681 gttgtatctg cttttccttg gctacaccct gccaaccaaa taattgctac aaatgtaatg
    31741 actacaaaac gaataatttt tttcattttt tctcctccac tttcaatgtg taattttttt
    31801 aatcagttga ttactgataa attgacttaa aaaaactaag attagaatca ataatgtagc
    31861 cacaatcgtt acatctgttt ggaatcgatt ataccctctc gatatagcaa gattccctaa
    31921 tccgcctgca cctactgctc cagccatggt agtcagtccg atcacgttga tgatagtcaa
    31981 cgccgagacc cgaatgatac caggcaaacc ttctaacaaa tacacacgta aaatgatacc
    32041 gattggactg gttcccatcg cttctgccgc ttcgatcacc ccaggatcaa cttctagcag
    32101 tgcgttctcg atttgacgag caaaaaacgg aacaactcca aaaatcaatg gcactaaagc
    32161 tgctttcgca ccaatcgtcg ttccaactaa gaaacgagta gtcaatgcta aaagagaaag
    32221 caagataatg aaagggatgg aacgaatgat attgatcagc ttatcaagta tttcaaatag
    32281 cagacggtta gctagtaatc cattagggcg tgtcactact aacgtcacac ctaagatgat
    32341 tccaatcatc ccgccaatga atgctgtcca aaaagacata tatagtgttt gcttcgtcgc
    32401 ttcgacaaat tcatccggaa tcaaataaac attgggcaaa tatgttttaa agaaatcagt
    32461 cattttatct tcctccttcg atcactttga tacgactatc taaatcgttt ttttgtaaaa
    32521 tatttatttt tacaccagat ttgatcaaat aatccaatgc ttttttccgc tgtttggttt
    32581 ctccagctaa agtaacgatc aaactcccta acggcgtttc ttgtaataac tctacattgc
    32641 catataaaat attcgctgtt acttgatatt tgctgtacag atgagcgatt agaggttcgt
    32701 tcgtctgatt tccaatataa cttaattcca ccagccattt attggcgatc tgatcggcaa
    32761 aagcagaatg ggcaatgatc gtttctaatg cttggtcaag atgagtagct gttcgaataa
    32821 aatctttggt caattcttct tcaggattgc tgaagatctg gatgctgcta cctttttcaa
    32881 cgattcttcc atcttccata accgctacct tgttgcagat ttctttgaca acttgcatct
    32941 catgagtgat caggacgatt gttaaaccta actggcgatt caattttttt aacaatgcaa
    33001 ggatctgaag ggtcgttttc ggatcaagtg cactggttgc ttcatcacat aataatacct
    33061 taggttcatt cgccaaagct cgtgcgattg ctactcgttg tttttgtccc cccgacagtt
    33121 gtttaggata agcagatgct ttttcttcca aaccgacaag ttccagtagt tcattcactt
    33181 tttgacgacg ttcctgtttc gattttccag aatactttaa agaaaaatca acgttgtcaa
    33241 aaatagttcg gctttccatt agattgaaat gctgaaagat cataccgatg gcctttcttt
    33301 cttttcgcaa ttctttggga gagagctgac tcagattcgt ctgattgaca atgacttctc
    33361 ctgctgttgg tttctgcagc aaattcatca cacgaactaa cgtacttttc cctgcacctg
    33421 agtaaccgac gattccataa acatcgcctt tttcaatcgt taaatctaca gaatctactg
    33481 cctgtatctc tttttctttt tgtttgaaac atacagaaac atctcgcaat tcaatcatta
    33541 aaattcctcc ttatctaaaa aaagcgtcct caagaaaatg aaaatgtcat tttcttgagg
    33601 acgctttttt gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca
    33661 agtacgatca tactctagca agatatcggt cgcagccgtc atcgccttac atctatgctc
    33721 gggatgaatt gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg
    33781 aagctctctg tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa
    33841 aaaaaagtcc ttttactaac ataaactatg tcagtaaaag gacgacgtat cgcggtacca
    33901 ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc
    33961 gttttaacgg tcgaacagtt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc
    34021 attttcagct tttcttactt gactcttctc accagccaga gcctctctgc aaagtttcca
    34081 aacttacttt ccttttcaac gaaatcgata ttttgttgtt gggattaatc tacatgagga
    34141 aaactgaaaa gtcaagtacg aaattcaaat tattttttct atatttattt ttctgttttt
    34201 ttatttaaca tttcaataac agttcgaaga tcttttcctt ccgcaagaag tttcaatttt
    34261 tccttttctt cgacggtata atttcggaca aaactggaat caggtatcaa aacaacgcct
    34321 aatcctgctc gtgaagcagc tgttgctcct actaaagaat cttccactgc aaaggctgaa
    34381 ctagcttcta atcctgttcg ttccaaagct gtcagataag gaatcggtga aggcttgttc
    34441 tccgacactt cgtctccgaa tgtaaacgtg tccaagtaat cagctaattt aaagtgatcc
    34501 aagatatctg ttgctctttt cgtaacagtg gtcgtagcaa tgcctagttt catatgacgt
    34561 tcttttaagt ctgccaatat ttcttttgca tatggtttta agtggatggc tccgcttgtc
    34621 agctgttgat aaaaatattc ttcacgcttc gctcggactt cctgtacttt ttcagggcta
    34681 cctgctgctt tcactaaaat atcaaaactt tgtttccagt tttttccgcc ccaagcgtca
    34741 acgatttctt ttgggatatg gatatcaaat tgctgaaatc cccaaagcca gccatcacga
    34801 tacgtttttt ctgtgtcaac taacaaacca tctaaatcaa atattgcacc tttcatctat
    34861 acattaatcc tttccaaaac aatacacata gtttagcacg actggtccaa aaagaacaga
    34921 agcaaagaac cagccttctc gtttataaga gttcttggaa tcgacggata tagattttct
    34981 tcacagctgt cacaagcgcc agataagcga tgactgtagc aaataaccat aaccagtaat
    35041 tgccaggaag tggcatcaag cctaattcag caccaaaact tgtaaaagga aggacagaac
    35101 cgacaataat tcctaatgta gtgataacaa acatggcaaa tgttgcgttg ctttggataa
    35161 atggtacttt cggtgtacgc agtgcatgga gcactaaggt ttgtgtccat agtgattcga
    35221 caaaccatcc tgcatggaat aatgcgatga aaatcactcg ctgtgaacta tccaatgtat
    35281 ggaaacttcc gcccactaca gcaggacaaa taacaaaata catcaacaag taagtagtaa
    35341 tatcaaatat cgaacttgtt ggaccaaagt aaaccatgaa ttccccaata ctagatgcat
    35401 tccatttttt tggctcgtcc aaatattctt tatccatccg atcccatggc aaggaaatgc
    35461 aggaaacatc atagatcaga ttcaaaaaca aaagttgtaa aggcagcatt ggtaaaaatg
    35521 gcaggaacgt acttgcaatc agcacggaaa acatattgcc aaaattagaa cttgctgtag
    35581 ccttgatata tttcatgata ttcccaaaag tttctcgtcc agaaagaagg cctctttcca
    35641 aaatcgtcaa atctttttct aaaaggatca cgtctgcaga ttctttcgca atatccacag
    35701 ctgtatctac agaaataccg atatcagcca ctttcattgc aggagcgtca ttgataccat
    35761 ctcctaaaaa tccgacagta tgaccatttt tacgtaaagc tgtcgtcaaa cgtgcttttt
    35821 gctgaggatt caattttacg aatacttcat ggtcttcagc tacttgtgct aattcatgat
    35881 cactcatttc cgagattttc tcaccggtaa ccaattcatt gatctctaga cctacttgac
    35941 ggcacactga acgtgtaact aattcgttgt ccccagtcag aacttttaca gctacaccat
    36001 gttctttcag agctttcaac gcttgtttcg ttgtttcttt tggtggatca aggaaagcaa
    36061 gataaccaat caaaaccatg tctgactcat ctttgactga aaattctcca acgacgcttg
    36121 gattggtctt ttgtgcgaca ccaatcactc gtaagccatc ttcattaagt gactgtactt
    36181 ttgcaagtac ggcttctttt cgttcttttg ttaatggtgt aacagtaccg ccaagatcaa
    36241 taaatttaga aatgttcagc atttcttcaa tcgcgccttt tgtgatcatt tgtgttttac
    36301 cagctggatc agcaaccaca acactcatac gacgacgttc aaaatcaaaa ggaatttcat
    36361 ccactttttg ataattgatc ttatctgtat ctaaagtttc tgttgcttca tcaatgatag
    36421 ccacatctaa caaatttttc agccctgttt gatagtagct atttagatac gcatggcgca
    36481 aaacacgatc atcttcattt ccttcacaat ccatatgata ttcaagaatg attttatctt
    36541 gtgtcaatgt ccccgtttta tccgtacata acacatcgat tgcaccaaag ttctggatgg
    36601 cattcaaatt tttgatcact gttccttttt tggccatcac acttgctcct ttgaccaaat
    36661 tcgtcgtaac gatcattgga agcatttcag gtgttagacc aactgctaca gatagtccaa
    36721 aaagaaaagc ttctagccaa tccccttttg taagcccatt gatgacgata actgctggag
    36781 ccatcaatga cataaatttg atcagtagca tggatgtttt atggatgcct aattcaaagc
    36841 ttgattgaat tggtttttca gatagcgttt ctgctacatg accaaatagt gtttcatttc
    36901 caacagaaac aatgattcct tccgcacttc cactgatgac attacttccc ataaagacaa
    36961 gattttcgta acttgtttcg ctttgctgat cgtcttcaca tactttcgca tgcttttcta
    37021 ctggatagct ttcccctgtc aatgctgctt gggaaatgaa taaatccttt gcggacaata
    37081 aacgcatatc cgctggtatc atatcccctg ctgaaagccg aacaagatct ccacagacga
    37141 tttcttccat aggaatctct gtgtactttc cattacgttt tacagctgcc gttactttca
    37201 caagtgattt cagtttttca gccgcttgat tggaacgtac ggactgaatc aacgtcattg
    37261 tcccgctgac gataaccata gtgaagataa tggctacacc gaaaagatct ttatctccag
    37321 gagctgctaa tacatattcc gtgatgaatg aaataattcc taatgcgatc aacactaatg
    37381 taaatggcgt gatgtatgct ttcaatattt ctacaatgaa tggtgttttt ttgccatatg
    37441 aaatcgcatt ttcaccgtaa ttttctcttg aacgttcgat ttgttcttct gtcaatccat
    37501 ttgctgatgc atggaatagt tcaaataatt cttgtttcgt ttttccagca aaagctgcat
    37561 agattttttg tgtatctttc tttttttcca tctcaatctc tcctttgtgt ccaaaagaca
    37621 gctgttctcg ctgcttttgg tctttagcta ttcatcggat cgatagagaa aaaactgaaa
    37681 ggggctgaga acagatagat aatagccctg gcctttcctc tagatccttg tttttcgaat
    37741 gactgtcatc catttgttct catctccttt actaagtaat tttaattcat gacttccaat
    37801 catttttcga atagttattt ttccaattag accacctcct ttttattttt caccgatggg
    37861 gatttgcggc aacaaaaaaa cctctcgcca aatactcagc gaaaggtttg aaaaagcata
    37921 ttaaaaaaag cttctcagat ctcatcgttg agttttgaca ctgtacaacg taaaaagcag
    37981 atacctgctt ttagctacct tatgaaaagc cttatctcga caattcctgt tctacccatt
    38041 ggcgtctctc gacgtttttg ggcagtagcc tatgtttgta taggagcctc acctaacaaa
    38101 tcttattcgg ttttccttcg ttaatataac aactaaaaaa gaggatgtca aatcaatttt
    38161 ccatgttttt catacttttt ttaaaataca cacgttatat tcctgtctca cgcggtttta
    38221 tttgtctcat tttccacctc ccgctataat agaaatatag taggaaacga ggtgctgtta
    38281 tggaaagaac acttgttatt atcaagccag acggcgtgag acgccattta gtcggaagca
    38341 tcatccaacg ttttgaagca aagggactgg ccattgctga aatgaagttt gaaactatga
    38401 ctcctgaatt agcaaaagaa cattatcagc acttgactga gcgcagtttt tttgatgaac
    38461 tgatcgatta catgacttcc ggtcctgtcg tttatcttgt gctggtcggc gaggaagtga
    38521 tcgatatcgt ccgtaagatg gttggagcaa caaaagctgc cgatgctgtt ccaggtacga
    38581 tccgaggaga ctacgcgctg ccggggactg aaaacatcat tcacgcttct gattcccgtg
    38641 atgctgcggt aaaagagatc gcccgctttt tcccgccatt cgatataaac aaaccgtctg
    38701 aaaaagcggc gaagtgatac aaattctaaa ctgctggtct agttgctggg ttcagcaatg
    38761 gccagcagtt ttttctctaa ggacctccgt tgattctttc ctaacatata ttcgagcact
    38821 gtgaagaatt cttggtagtc tttcgtcttt tcttccccta aagcagcaga aatcaatctt
    38881 tgataataat ctgccatcaa tgtttcatag atcactgtac ttctttcttt atgtgataag
    38941 ctccgtttca tatcttcatt cacactacgt gcctttttca accgaccatt ttctatataa
    39001 aacgaagtca ggttcattaa aaaagtaaag agatactgct catgattgtt caactgtgct
    39061 aatcgtcgca ttcttttttt gattttcaaa taattgttct caatgaaccg atcactgaat
    39121 atccaaggaa aatcagctag aatagatagt tcaaattgac catagtctgg tatctgcatc
    39181 aagtattctt caatgattcg gcattcataa cgtaaaaatt caaattctgt ctcagatact
    39241 tctgtttttt cgaccatgtg aagattcaaa accaaataat acagatcttc tgttttctta
    39301 aaatgcctac ggttattgct gatctcttta taaggatcaa agctgtcttc ttgtacccga
    39361 tctagcattc gtcttttttt ctttaacttt attggttcat ccagctggtt tcgcatccat
    39421 tcatattctg caagtgtcat gttcattcgc tctaaaaatg atctcaatgt tacaaatgac
    39481 atttttttca ctgaatttgt ctcaatcccg actagagaag tcttaaaaca gattccttcc
    39541 gctaattggg actgtgtcaa cttcttgttg actcgaagtt tcttgatcaa ttcaccatca
    39601 tacataatag ttctcctttt taatttaaat ttttccacat tcaataaata gatacgttaa
    39661 aaaggaaaaa tacacgaaaa aaataaaaaa atgttttttt cataaaaaat accaaccttc
    39721 aagcattaga atgttgtcta actactgaag gttggtttga ttgtttattg attatttttt
    39781 tgctgttcaa cgtctgttct tgttactgga tataagttgg ttgttgtttt attaccattt
    39841 tttgaaaaga cacttgtcga atgttcgcct ttttgctttt cgattgcttc attacgttcc
    39901 gcttcatttt tatagtcata ttttttcgga tcaatcgtct caaatccgtt tggcacataa
    39961 aaccgcaaga gattttcctg attcagctta tctgaaagac ttaacgcagt cttgactttt
    40021 tcctgatctt tggagatttc ctcatcgatt cctgctgctt tcgtatcgat gatttctcct
    40081 gtctgattat tgtaagcttt tcctcctagg acggtgtatt tgggtgtcac aaagttccca
    40141 tttcgaaaag caactacttg atcatgctga gaagataata agtctgtacc aaaatgaaga
    40201 taatctttat catcgattcc caatagatgt agtaatgtcg gcaaaacatc gatttctcca
    40261 ccgtattcat gattgactgt ccctttagta taaccaggca tatggatcat caatggcact
    40321 cgttgcatct gtgcgttgtc aaattcatcc catgtatctg gatctttacc aagagcgctt
    40381 gctaaatctt tattatctgt attcgagatc ccaaaatgat ccccgtaaat cacaaagatt
    40441 gaattttggt aaataccaga ttttttcaaa tacgtaaaaa attgttccaa tgattgatcc
    40501 agataatgtg ccgttcgaac ataattatct actgtgctat tgccagtatt caaagatgga
    40561 aagtcgaaat tcttgtcatc cgtataataa ggcgtgtggt tggttacgga aagaaatttc
    40621 gtgtaaaacg gctgttgtag atgctcaaga tattgggcag attctctgaa taaatcttta
    40681 tctaatatcc cataacctaa cgtttcgtcg gattcatcaa aataagatcg atcaaagaaa
    40741 ttgtcataac ctaagttttt atatacatga tctctattcc aaaaactagc tacattccca
    40801 tggaaaacag cgcttgtata gccttgcttt tgtccaagga tcgctggtgc ggcttgaaag
    40861 acattgtctg acccaagttc tgtgaataat gagccttgag gtaaaccaaa tgtgccagtt
    40921 tccaacatat tttcagcatc acttgtcttt ccctgtccta cttcatgaaa gaaattgtca
    40981 aagctgatcg ttgcttgatt ctggaaaata ctatttaaaa acggtgtgac ttcttgtccg
    41041 tctaccttca tattaatcaa aaactgctgg aaactttcta aatggagaac gatcacattt
    41101 ttccctttag cgatcccaaa tgtttcggga tttggctctg cataatgttt ctttgtataa
    41161 tctaaaactt catcaatccc attactgctt gcatgcgcgc gaacactgct agtcattcct
    41221 gttttgattc cgtcataaat agtatacgca tcgattccta gatatttgac aatatatgaa
    41281 cggtcaaatg ttcgctgcag caattgtgga cggttggctt cgctcagcgc tagatttcct
    41341 gaaaaaataa gccctgaaag acaggtaaca gcgatagcca tcggtttgcc gacagggttg
    41401 cttttgatag gtattttctt gaccttcaac caaaccagta gcccaatgaa cacagcgata
    41461 tccagccagt agatgacatc atggggcttc atcaaagaaa aggagcttcc tgacaatcct
    41521 tgcgacactt tcgaaaagcc taatacagat ttgactgtaa tgaaatctgt gaattcccga
    41581 taaaaaataa tattcaagta caacaaaagc gtatttaaaa tatcaatgat caaaagaata
    41641 gctaacgctg gctttggctt tttaatatac aaagaaaggc caaaaaacaa taaggtagtc
    41701 gcaattgggt tgatccacaa gataaagtac tggatcgtac cttccacacc taatgaaaaa
    41761 tctgcatagt aggcaatgat cgtcttcagc cagaaaaaga aaacagctgt caaaacgatt
    41821 gctaaacgat tttggcacaa ttttttaagt tgtgtcacgt atatcacttc tctctattca
    41881 cattttttct tattttgctc ctgaaaaatg aaaatttcct aaaaaagttg ttatcttaag
    41941 atttttttat tctttctaaa gattattccg tccacttttc acagcataaa accgctgcga
    42001 tgtaagcgat taaactaatg aagagataaa agtcttgtgg tgaccgcttc actccacggt
    42061 attcaaaagc cagtttctcg gtattcgtac aaaaaaagag gctgtgacaa aattcttgtc
    42121 gcagctcctt atttcttgat gcaggacagc tttttcacaa cttcttcctt aaacggtgtt
    42181 ctcctgccaa ctcctcggcc acaagtcaca atatttataa aacatgagaa gctgtttttt
    42241 gaaattgttc cttgtggctc agagttaaac ggcaggctca agacctcttg atacacggtg
    42301 ttcaatcagc tgaccctcgg tattagatta tgtcaggacg ctaattttac aacctcttgg
    42361 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaatataag
    42421 gagctatttt ttgaaattgc tccttgtggc tcagagttaa acggcaggct caagacctct
    42481 tgatacacgg tgttcaatca gctgaccttc ggtattagct caaaaaacgg caaaatatga
    42541 ggaactattt tgccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
    42601 tgtttttcat tgtccatagg attgatattg tccttgtgat gactcattcg taataattga
    42661 ggcttgattt tcttcacttc ccgttatcgt ttgtccactg ccagaatctg aaggacttgt
    42721 tcctgtcgac tcgttttttt gagaagagac agttgttttc ttgacttgtt catttgtctt
    42781 tttccattcc gctaaacgat cggcgaccac ttttttgtct actttttcag aataagcggt
    42841 gatcactttt ccatttttca aacgggctac tttgtcgcca tcatgagtca aaagcaaaac
    42901 ggtcaaatgc ttgtctttaa attgatattg tctgagagaa atcgcactaa gtacgtcatc
    42961 gatattaata aattgatttt cttcttttcc ttttggcaaa taaatgtcca attcgccttt
    43021 ttcgtaattg gcagttattt tatactccgc ccaccaataa gttgagaatt cttttttgaa
    43081 attatctact gattctttgc ttgctacgat tttttctgtt tctttctgag caagatctgc
    43141 tgtcattttt cctgaaaatg ctgcggataa aataagcagt aagaaaaaac cgaataacca
    43201 aaagagaaga aacggtcttt ttttcctcat gctttcctcc actcctattt aattttgact
    43261 attctattat atacaaaaaa tgaaatagaa agacaaaaaa gttgaaaaag atcgtaaata
    43321 attgaacttc tttttcacaa aatggtaaga atggagaatt tcacgcattt gctctcaact
    43381 attctttctt aagcctcaaa tccgttttta tctgatacgt ctttgaacca atgacccgat
    43441 tttttgattg ttctttttcc atcttgtgct aagtctactg aaataaagcc atatcgattc
    43501 ttatatgcat tggtccacga ccagttatcc atacatgtcc acatatgata gcctaaacaa
    43561 ttggcacctt cttgaatggc ttgatggaca tatttcagat gagattggac aaattcgatc
    43621 cgataatcat cgtggatcat gccatcttct ttgataaatc gtgcttcgtt ttctacaccc
    43681 ataccgtttt cagaaataaa gcagtcgata tttccataat gatctcgtac attgatcaaa
    43741 atatcataga ttccttgttc atagatctcc catccgcgat aaggattcat tttacgacca
    43801 ggcatttcat aattgtcgaa ataatcctca ggcattggac cgtttttagt atcgattggt
    43861 gtttcttttg cttttacccg gcgtggctgg taataattga tacctaaaag atctactgta
    43921 ttttctttga taaccgtcaa atcctctgca tggatcacag gcatgagatc aagttctttt
    43981 actatctcaa tcaattcact tggaaactcg ccttttacag ctggatcaag gaatgaacga
    44041 ttgaagaacg catctgctat ttgcgctgct ttaacatctt cagggtttga ttcgtctctt
    44101 ggatagcttg gtgtcagatt caagatgata ccaataacac caccttgctc catttcatgg
    44161 taagatttga tggctaacgc tgaagccaac gcttcatgat agccaacttg gatcgctttt
    44221 ttcatatctg actcttctgg ataatgccat cgatataaat aacctgcttc gactggaacg
    44281 attggttcat tatgagtaaa ccattttttt actttcgaac caaacaattc aaaacaactt
    44341 ttggcatatt tttcataggc ttcaaccgtt tctcggttca accatccgcc tttttcttgc
    44401 agatacatcg gcatatcgaa atgatacaga ttcacaaagg gttcgatacc gttttcaatc
    44461 aactcatcaa aataacgatg atagaaacga acggcttctt cgttgattgt tccagattca
    44521 tcaggtatca aacggctcca ttggatagat gttcgaaatg aattatgccc agtctgtttc
    44581 atcaactgta catcctcttg atacttcgta taaacttgcg aggttttttc aggtcctact
    44641 tgatcaaaga acttttgcgg ttcttttttg taccaataat caaaaatgtt ctctcctttt
    44701 ccatcgcctg aaatccttcc ttctgtttgt gggccacttg ctgcagaacc ccaccaaaaa
    44761 tttgctggaa attgatattt tttcatcaaa gcacctcttt ttctttttta gttcgtttta
    44821 gttgattcca tgtatgatat tttccatcac aatcactttt tcattttctt cctcttcttt
    44881 tttgattcgt tttaacagct gttctgctgc tcgttccccg attttatctg ttggtggcgt
    44941 gatcgtgatt ttcggaagga tactcagatc gtttttatct aaataatcat agtgactgaa
    45001 cgcaatatcc ttcccgattc tgacaccttc ttgattgaaa cattcgatgg caccaatcga
    45061 catattgtaa ttgctgacaa aaatagcagt tgcccctttt tctaataatg cttttgcccc
    45121 gtaatagccg ctttttctag aatagtctcc tgtaaagacc tctaattgga tcgatggatc
    45181 attttggacc gcttctttgg ctcctgctaa acgttctctt gctacgtagt ctgtttgagt
    45241 ggcagcaata aatccgattt ttttatgtcc ttgttcacca tgatgagcga tcacttttgc
    45301 tacactttct cgatcattca ctaatattgt atcaatacct gctggtcctt ctggacaatt
    45361 caatgcgata actggaatac tcatttttgt gagcatttca aatccagacc actcttcttc
    45421 ggataagaag acaatcagcc catcgatcac atgcttcatc aggtattcaa ttttttgttc
    45481 aattttttct ggctgatcgg caaacccgct taataataag ctatacccat tttcttcagc
    45541 tactctttcg atccctgaga caacttccga cccaaaacgg ctggaaatcc cgtttatcaa
    45601 aagtccaata gagaagcttc gattattctt caacccttta gcaatgatgt tttctttata
    45661 gtccaacgct gaaatcgctt ctgctatttt tttcatgttc ttttccttca gttgctgacc
    45721 attcaagtaa cgggaaactg ttcccactga aacaccagcc atcttagcca catcacggat
    45781 cgatgccata cattctcact cctgccagtt acatttgatt tctctttctt gttgttcgat
    45841 tatgatgacc gcattctttg catagtgttg cttgtcatca atatccatat aactaaagtc
    45901 ttcagtagag caacttcctc tcactattaa ttatacttaa acaagtattt gaaccggttc
    45961 atttttaata tagcattttt ttaaaagatt gcaacacttt tttaaaacgc tttctgaaag
    46021 tggcggattt tttgcctttt taaaatttta ttctaaaatt tactctattt gtgggtgttt
    46081 tgtgcgtttt tctcttccat ccgtttgaag ttttacattc caatggtata atttctttat
    46141 cctatcaaat gggggaagta ttttgaagaa attaatcgta ctatttattt tgtctgcggg
    46201 acttttgaca ttgactggct gtgatttgtt tggcggctct gaccaatcct cggacgaaac
    46261 aaccgattct tctgtcttaa aagcggaaaa agcagatacc accaacagtg tatatacgct
    46321 aaaagtacgt aaagatatgg atttatccgc gggacagttg acatttacag ataaaaaaat
    46381 ggaatggaca cgcacgtatc agacacaagg aactgattct tctgaatcat ctgaagaaaa
    46441 aacagtgctg acagatatca agatcactac caaagatgac gaatatatta tttcaggaaa
    46501 agaaaataaa aaagaaacaa cagtcatatt tacaaaaatc ggtaattacc gtttgaagga
    46561 tgaggatggc aacatctaca gtctatagtg ccgtctgttg gatcttcttt tgtttctccc
    46621 cttcttttct gctatagtaa agaagcaaga tgattgtaaa ggagacgaaa tggatgatcg
    46681 atagtcctga ttattgtaca tgtaataaca acaaaaatat ccatacagaa tttaatgacc
    46741 aaggaagctt gagcatatgc gacaactgtc acaaactagt caaagattca tttaaaacat
    46801 ttgaatctta tcctgttcaa aattatgtaa aaagtagaag aagataaaca aatccaagca
    46861 aaactcacta tggctgattt ttatgaactt caaactcagc ttcttccttt gatcaagctt
    46921 catcagtaaa acaaacagtg gatcatttca gtttacaaat caaagagtaa agatttattt
    46981 atttcaaata tttgaatata aaataaccaa acgatagaaa ggcttattct acatcacgta
    47041 gtaatttttc tttcccgtcg tttggttttt tatttttagc ctaattcttg accttttgca
    47101 tgctggttat ccgtaaaata ttttccagca ggctttcctt ccaattcagc taatttttct
    47161 tggatctgac ggatcacctt ttttgcatct tctggatttt ctacaaaatc gaatttatcc
    47221 ccatccactt gtattttagg acatacatca aaatcttcat accattgatt atagcgggtg
    47281 ttcaacgttt cataataggt atataacgtc tcatcgcttt ctagctgttc atagtcacgc
    47341 ccacgttttt tgatacgttc tagcatcgtg tccaaagaaa ctttgatatg gaccatcaaa
    47401 tcaggccgtt tttttggagc aacatcatct aactcgttta gcatcgtatc taataagcta
    47461 tcgtactgct gtacttcgat atccgttacc cgacctaaat cagcgtttag atggaacaac
    47521 aggctatctt catagatgga tcggtctagc acattgtcat cgttcactaa agcatttttc
    47581 attgctaaaa atcgcttgtt caaaaagaag atttgcaata aaaaagcgta ctgctcagga
    47641 tttgaataaa agagcggcaa tacttcgtta tcttcgacat tttcataaaa tggtttagaa
    47701 tcaatctctt ttgcaagcat atccgtcaaa ctgctcttac ctgcaccaat cgttcctgaa
    47761 atcaaaatca ctgacataca acccttcctc ttctataagt actcgcctac gtaagtttca
    47821 acaggcaatg tttcaaaatc atattcacgt acagcttggt ctgattttaa atacgtatgg
    47881 agactttgtg taatcatcaa gttcgtaggt accgtctctt cttgtacaat gatcatcggt
    47941 tttttcaaca tagttgccac acctaattcg taagccgttc ctggatcgat tgtttgatgc
    48001 tcaaagtcaa ggatagcaac aacaaattct gcatttgtca gttcttccat atctttttcg
    48061 tatacttcct gcgcccatcc agcgctgaat agttcataat tgctttcttg gtgatgacgt
    48121 ggagagtaga aacttgtgac tgttttgttt tcctccaacg ctttttcgat acgacttact
    48181 cgatcgattt gctcctctga aaaaaatggt cctgctaaat atatttgact cattattttg
    48241 cctccttcaa taataactga tttttaatag atactgctcg taattcattg accagttcca
    48301 atggattgtt ggaaaagatt acttgatcca accatttttt atccataaaa tcctcttttg
    48361 caaaagtttc taataattgt tgcaagccgc tgtaataacc gccaatattc aatattccga
    48421 ttggcttgtc gggcgtcaga ccgattgcta tccaagaaag aagttgtgag aattcctcca
    48481 atgtacctag acctccaggg aaaacgagga cagcatctcc cttttcaaat aataatacct
    48541 ttctttcatc gatcgtttct gtaggaataa atgtagtaac atcttttcca ggcaattcag
    48601 tttcaaaaag cccattcgga tagatacctg tgacttttcc gttattttcc agtactgttt
    48661 tactaatcac tcccataatc ccggagtatg aaccaccgta aaccagttcg atttcttctt
    48721 gtgccatgta ttttcctaac gtttgcgcaa taaatttgta actttcttta ttaccaaaac
    48781 gggaaccgca aaaaacagta agtttcataa aaaaacactc cctaactcaa aagtctatct
    48841 tcattctaca cgtgtttttt taaaataaaa gactagattt tgtagttttt tagtggtata
    48901 taggatagac gccactatat atagtattta gaaaaaaatc atttttcagc cattttatag
    48961 ataaaacaaa aataaataac gtgttttcat cgatatgaaa tgacttactt atagaagata
    49021 ctgggatttc gtcctatatg ccaataacgt gtattatttt aaacaacaaa tacttgtttc
    49081 ttttattaac gaaaaaatca ttttgttctc gtgttatgtt tcactgataa atgatgtttc
    49141 tctaaataaa aaagccgacg aactaaacga tcaaaatttg atcatttttg ttcatcagct
    49201 tctcctaaaa atctttttgt taacgataaa tagctggatt tgtaaaaata tcacttgaat
    49261 cgtcactgct ggaagaaaat tcagtgataa ccgcacctgt tgcgcctgcc tggaactagt
    49321 gtttgatatt gggctcgaac gtgtactgat ctctagcatg aagaataatt tcttttttta
    49381 ctgtataata actttctttc ctttttggaa tagtacagga aagttttttt gtttcctttc
    49441 cttcgacata aggtatacca gaccctttcg acaacgaaag gttctcattt ttccttcatc
    49501 gtcatttcaa ggagggtgcc gatgctctgg acagtttcga tcgctcctaa accaaaatct
    49561 gtatattcga ttctttctaa ctctgattct ttcataccat tcctgtctca aggtacatct
    49621 attgtacttt tttcttgtaa tccattctgc ctctcctaac taattgtcaa atcatcccaa
    49681 gatatgtctt cttcctcttt ttcttcttgg atgatttctg cattcggatc tactggtttt
    49741 ttcaataata aaatggttat tcctgtgaca aaagaaccag ctaacaatgc accaatgaat
    49801 gcccatggtc tggtcatcgt agcgactgca aacattcccg atgccggaat acggctatct
    49861 gcgccccaaa acatgcttaa tccgccacct actgtcccac cgactcccgt tgctatgaca
    49921 ttgcgtgcca agtcgttcaa tacgataggg aaacatccct ctgtgatctg acagatcccc
    49981 ataggaaaag cggtcttcaa tgtatcgatt tcttgacgat tgagtatatt tttacgaatg
    50041 attttcccta agaaataagc gatcgtcaag ccgaatgggg ttaccatcga agctaaaatc
    50101 aatacagtga ttggttcata gattccttct gaaaatcgtg ccacaccccc ttatccagaa
    50161 taaatggtaa tccagaaaca gccgtgtatc tgcggtaata agcctaacca aacgaaaaat
    50221 atgagaagct atttttgttt ggctgttctt attacttgat gcagggcagc tttttcacaa
    50281 cctctttttt tatttatgtt tcataatcaa tatggtaagg atgcagctcc gtatggtaga
    50341 ccgcctccga atattcaatc atttccccaa tttgcgtaga cgatttccgt atccgtttga
    50401 tgccgatctg tgcgtctgtt ttcagaattc cttgttcttc ttctgttaaa aatactgccg
    50461 agaaatcatc agaaaatgag tcaatagtat atcctttttt cgtcagcaaa cgatacaaag
    50521 attctttgcc aaattcttct ctgctgaatt gcatcatttc ttgtggaaga taatgaacaa
    50581 aataaatata aggctgattg ttcaaataat ataagcgctt aaaacaaaca gcttgctcac
    50641 cgaaaaagga aaacaaagga tcttccttct ttatatggac caattgcaaa tccagcgttt
    50701 ctttccggac ttcatatcgg gagttctcca agatttgcgt aaagcttgcc gctttggata
    50761 atcgattgta aggacgattg cttagaaccg tcgtcccacg accacttttc tttgcgacat
    50821 attcatctga tgccagcagt tcgattgcct ttcggacagt gattttgctg acttgaaaca
    50881 gttcttctaa ttcactttct gtcggcaaca tcgaaccgac tggatatttt cctgagaaaa
    50941 tatcttcttt aattttatct gcgacttcca agtatagtac acgtgtcctt ttcataacgt
    51001 caccctttgc tttactatta ctaaaagaat agcacataaa aaataaaaaa agaacacaaa
    51061 tcacatgtga gaagtgtgtt ctttttcatt cagctgcttt aattacaagt ttacgccatt
    51121 tgaggcaatt acttctttat accaatcaaa agattttttc tttgatcgat tcagtgtccc
    51181 atttccttca tcgtctagat ccacatagat aaagccgtaa cgtttactca tttctcctgt
    51241 tgatgcactg acaagatcga tacatcccca aggcgtatag cccatcaaat ctacaccgtc
    51301 tgctactgca ttagccatcg cttcgatatg acgacgtaaa taatcgatcc gataatcatc
    51361 aataatcgtg ccatcctctt ccatatgatc aatggctcca agaccgtttt caacaatgaa
    51421 taatggtttc tggtaacgat tgtataattc attcaatgcg attctcagcc cttctggatc
    51481 gatctgccag ccccattcac ttgcctcaag aaacggattt tttactcctc ccagcaagtt
    51541 cccttctgaa gttgctgctt gtggatcagt ctcattgatt gccgtagaca tataataact
    51601 aaatccgatg tagtccactg gatattcttt tagcaactgg aagtcttttt ccgtttgctc
    51661 taatttttcc ggatcgactc catatttttt atgggtacgc gctgtgtatg cagggtattc
    51721 tccacgtact tggacatccg tgcagaaaaa attgaattct tggttttgga tcattgttgc
    51781 tgcctgattg actggattgg catcgatgct gtaagttgtt gcatagataa tcatgcagcc
    51841 gatttggata tccgaacgca attcgtggcc gatttttacg gctttgctac ttgcaacgaa
    51901 ttgattatgc catgcttgga aaatattttg gtactctcct gctccattgc tttttactaa
    51961 tccttgactt aaagctggaa agtgaaaggc cgaattgatt tcattgaaag tcatccaata
    52021 tttgacttta ctgctgtatc tctctaatac tgtctgagca aatcgttcat agaagtcgat
    52081 cagttttcga tttttccagc caccgtattc ttttgccaaa tgaagaggca tttcgtaatg
    52141 agaaatcgtg atcacaggtt caatatcata ttttaagcac tcatcaatca gctgatcata
    52201 aaattctaat cccgcttcgt taggagtacc ttcgtctcca tttggaaaaa ttcgtgtcca
    52261 ggcaatcgaa aaacgataac atttgaatcc catttccgca aacaaggcaa gatcttcttt
    52321 gaaacgatcg taatgatcga ttcctcgatg attcgggtaa atatattttt cttgatcaat
    52381 cgtccagtca aattcttcac tgccgataat cgcaaagcgc tgcttacctc caggcatagc
    52441 atctgcaacg gatagtcctt ttccgtctcg atcataagcc ccttctaatt gatttggcag
    52501 cagttgctcc accccataaa aatttttctg aaaaacgtga ttgcatcctg atttcctcct
    52561 tattttacaa ttgccagaac atcttcgttt gcaataatct ctttttggtc taattcaagt
    52621 atatcggcaa atgcatcagt attcgtaatg acaactggag tgattacgct atagccagct
    52681 gctctaattg cttcgatgtc aaaacgaatc aataaatctc ctgctttgac gagatcccct
    52741 tgtttgacta agatctcaaa gccattccca tttaattcta ctgtatccat cccgatatga
    52801 atcaaaatct ccgctccgtc agtcgttgtg atccctacag catgtccagt tggaaaaata
    52861 gtcgtgatct ctccgtctgc aggtgcaact agttctccta cttctggatc aatagcgata
    52921 ccttttccca tcacgccaga agaaaaaact tggtctggta cttcactcaa tggcagtact
    52981 ttacccgtta aaggactttt taaggtatgc cgtgctgaag taatcggttc tcctgcattc
    53041 gcatgtttgt tttctaattg attgtcttgt gtttgttcgt caaatcctaa aatcaatgta
    53101 cctacgaatg caagaacaaa agcaattcct gtagctatta ctgctactgt cacatttgac
    53161 tctacaccat ccaccgtatt aatgaaagtc ggaatcgtca ataagctgac caaactgctg
    53221 gagaaagctt ttactccgga aaatccgata atagctccac caatacctcc agaaatacaa
    53281 gcggcaatga atggtttctt caaaggtaat gtcacaccat acacagttgg ttcagtgatt
    53341 ccaaataacg aagtcactgt agaagaaatc cctaatgctc gaagtttcgt atcttttgtt
    53401 cgcaatgcta cagctaaagc agccccacct tgtgccaaga tggctggaag aagcattggc
    53461 atcaatacat caaacccata ttgttcgata ttcaaaaaca tgatcggtac gaatccccaa
    53521 tgcatgccga acatcacgaa tacttgccat aaacttccca tgattagacc tgctacgatt
    53581 ggactaaatc cataaatcga gttgaagaga ccgcctaaag cattaccggc aaccgtcccg
    53641 attggtccta aagcaagaaa tgttaatgga accatcacta ctaaaacgac aagcggaact
    53701 aaaatcattt gcagaaattg cggaatcact ttttttacga atggctctaa tttactttga
    53761 acccatacgg ctagaatgat tggtatgaca gaagaagtat aaccagatgg tgaaagaatc
    53821 actgggatcc caaagaaact gatagcttct cccgcaccag caactgctgt gatagctgga
    53881 tacacaagtg ccatagcaat tgctactgct aaaaactggt tggctttgaa ctttttagct
    53941 gctgtaaaag caagcatgac aggtaagaag gtaaagacac catctgctgc agcaaacaat
    54001 atttgataag taccgctatc agctgtcagc cagcccatca ccgttgccaa tgataagaat
    54061 cctttcaata ccccggcggc tgccatcgcc cctagaaaag gtgtaaatat actagagata
    54121 atatcgatca gacgattcaa aatatttttg gactcttctt ttccatcctc cgaaactgca
    54181 agaccttcct catccacgat cgattgataa acatctgcta cattactgcc aatcactact
    54241 tgatactgac cgccactttg tacgacttgg atcacgtccg ggtcttcttt taacttttgc
    54301 gtatctgcta aagattcatc ttttaatctg aatcgcaacc gcgtagcaca atgtactaaa
    54361 cttttgacat tcttttgtcc tcctaccgct tcccatacac gacgaccaac tgcttgatta
    54421 tccattgttt tttccttctt tcttttttat ttaaaaaata aaaacccaga ttgaaaaaaa
    54481 cagtcacaaa cattcgtgaa cctatttttt caatccaggt tttgcctgcc atacagtaac
    54541 aatccttatg attggatgct ttttttctca cttactactc tttgaatatg aatcgttaaa
    54601 taaatctgct ctgcgatccc catttcctgt ttttgcgttt gtcgaagata ctcattgatc
    54661 cgttcgacac aatgaaacgc ttttggatac tttccttgaa ctaatgcgta gagaaattca
    54721 tcttgctcgt cagatccttc ccctttgaga taacgctggg caaaaaactg cagatgagta
    54781 atgatacgct gataattcaa agattcttca tcgaacacga tgccgaagaa tttactgatg
    54841 atactcagta tatctcttac cattgtggta gcggtcatcg tcacttgcat gtcttcgttt
    54901 ccttgttggc tattcacaaa atgaaaggca ataaaaccgg cttcatcctc agaaagttcc
    54961 acacccgtct tttgtttcac gaacaaaaga gcctctttcg ctgcttgata ttctttcgga
    55021 taaaattttt ttgtttcaaa taataatgga ttaggcagtt ggatattttc ttttgctcgt
    55081 gtgatcgcat aatgaagatg atcggtcaat gtcagataaa tattaggcga aaattcaact
    55141 tttagtttat cttcagccag ttcgactact tgtttgaccc attcgatctc ctctgccgga
    55201 atatcagcca tcagctgctg gaattggttt ttagcaaaag aatctcttaa acaaattctt
    55261 tttggaccgc ttctggcgaa atctcgtccc caatcttttt ttgaaaagct agtccttttc
    55321 ccatacaaac gacttcttcc ccgaatccat ttttcgaaat gacgacattg ttattcaaaa
    55381 ttttatcaat tttcattttg cttcgccctc tcaagaaaaa taaaaaaacc tagaattcgc
    55441 ctactgtttc ttagctgaat tctggttttg cctgccgtac agtaacaatc catttcttat
    55501 tcaaaatcat cataccatcg aatttttatt tatgcaagcc ttttcatata aaaaataaaa
    55561 aaactggaac acaagtctat ctagaaaaca accaaatcag agatgcacct ctttgcgttt
    55621 ctcttttttt cagcaaattg gtttttcctt atcgattcat atcctttggc tgtttttaat
    55681 ctgtaacgac ttatgtccca gtatcctaaa atgtttttgt ctctagattg aaagcagatc
    55741 tcatatcatc tgtcgcatct tttatcgatg taacactttc cagttctcct tgtacaacta
    55801 gtcgcgtgac ggcgtccatg tcgccacaag taattagtgt gacaatttct tttccctcga
    55861 cttcattcag taattgggta tctgtaggag caactttttc tttaaaaaat gttttgtatg
    55921 tatacacatt ttctaaatct gtcaaataga tcttggcacc catctctaaa ttttctagcg
    55981 gtgtaaacag caattcaggg ttcgttgcac gatggcttgc taaggcataa tttccttttc
    56041 ccatttcttg atctggagat aatgttcctg ctccgtaaag tagtgacgta ttatccaagc
    56101 ctttgaaaac cggtaaattg attgaaactg aagggactgc gatactagca atcactggta
    56161 gatctgttcc tctcatttgc gacctcatga ccccttctgt cgtcattggt tctaccgcat
    56221 caaagtcaaa actgacatct ttatcgttat tctttttcag atcttctttt gttacattcg
    56281 ctatagcata tttatctcct gtctctctga caaaataatc cttgatctgt tcattgaaaa
    56341 tcaaagctag tcctactaat aacaagagga acaagaggat attgactagc catctttttg
    56401 cttttccttt ttttttcatt ttctctccct ccagactcat tttactgttt ttcttttgct
    56461 ctttccaaca gccgaatgac acatttctac aactctgtgt atttttttcg tacacctgcg
    56521 cttttttcta caggatattt caaattattt ttgatcaatt tttcttcaat gatctcatct
    56581 agatccaggt gaaggttgtc tgccatcatg tatgaataga tcaatacatc tgccagttct
    56641 tctttgattc gttctaattg tgtttctttt acttcttccg gcgttttcca ttgaaaaagt
    56701 tctaacaatt cagatgcttc caaagaaata gagatagcca aatctttttc gttatgaaat
    56761 tgtcgccaat tacgttcatc tctaaactgg ttgacttttt ccatactatt catttgcttg
    56821 ccttcttcca atcacttctt acttgattaa tcataccatt tttttacata aaaaatagat
    56881 gatgctttta aaaaaactcc tgttttcttt tatttaaaat aaatgtcata gaaaatcaat
    56941 aatttaggta gccaccatgt gtatgcagta gcgtgtcttc ttcccttgag gctttttgtt
    57001 tttcgatacg ttcttcttcc caaacagaca acgctactag aatctctctt aatgattttc
    57061 cttcttcggt gagcgagtac tctactttag gcgggacttg gttataggct tttcgatgga
    57121 tactttcatc ttgttctaac tctcttaact gctgggtcag catttttttt gtgatcgtag
    57181 ggatttgctt gcttctccac gcctaaaata agcgatattg ctcttccctt tatctggtgt
    57241 aagcaaagca gttagcattt tgacgatcgt gggttccgct tttcacttct tatctactta
    57301 gtatcatgaa gtatactttc gtactaatac taagtagcgg aagtgtcaac tactttgttt
    57361 aactacatag caaaagaaac agaagggtga caacggtcat cacgcttctg tttcttttga
    57421 atatgctgtg ttgttgtctc tatctccgtg tagactttcc tcaaacttat cctttgacag
    57481 taagtcagta ggctgatttg ctctttctag atgccagata catttctaca aaaaaatagt
    57541 gattctgttt tgaaaattcg atttttagtt ctgcattttc gtaaacatcc aacatttttt
    57601 tcgcactgta tagacctaac ccgccatttt ttttagaggt ttttcctctt ttgaccatct
    57661 ccgatagcgt caaattcgtt ggatttgcct tgttcgctat actaaaacgt gatccctctt
    57721 tttcttccag cagattgatc gtaatcggac tctgatcggc tacacgatga tcgaatgcgt
    57781 tagaaataaa aatagataaa cagcgaataa aaacaaccag atcaatcggg attgttttca
    57841 cttcgacagg aataactact tggatcggga ttttctccga ttctgctttt tctagaaatt
    57901 ttaaaaagac acccctgaca gctggggata caatatttgt tagctgttgt atttgcggtt
    57961 tttcaaaaat agctgcagaa tgatcttcta atatttctaa aaattccaac gtttcttttt
    58021 tattttcctg aagagtaatt tttaatgaaa acagtagact tttataatca tgtttgaatt
    58081 cctctagatg atggtaatat tcttcattta tttgatacag ttgaagcgat tcctgatgtt
    58141 gtctttcttt tacttggaaa ctgatcaaca taatggaaaa aaacaaagaa aaaaaactga
    58201 tgactatcga caaaagagat agaagcagat aattagatga gcggaagtga acacttccca
    58261 ataccaagta aatcacgccc cagcttaata aaatacaaat acctccaaaa tagtgttcag
    58321 ttggataagt aaaaagcaag ttgagaaatc tcgtctgttt gtctatactt tttactaata
    58381 gatagaaaat aaatgcgata agtagtgcaa aaaaacttgc tgttccaaga tgtctctttc
    58441 ctaaataatc catcagatca aaaaccagaa aaaagctgag tccagtgata gcaaaaaaaa
    58501 gattactgat caaacagctg ataaacaggt ttttcgtagt aaaataaaaa agaaacatca
    58561 ataataagcc aactaggtaa ggaaagctca ctttagggat aggaagtaaa agtgtcacca
    58621 ccatcaaagc tatacaacca aagctgtttt ttactagcag ttgtttcgaa aagaataaat
    58681 agatacctaa atctaaaatc aaagtaaagg tcaaataaag tgtcactgtt gcgaccatct
    58741 tattcctcca ttgttttgtt tcaaaatgta cacatatttt tttaatagga gcctgcatat
    58801 gaaaaagtat tttatcatag aagataacca gtttcacagc gaatggatca tcagagaatt
    58861 ggtcaatcat catatcgaga atatcgtgca gctcacttct atctctcaaa tcaatcagtt
    58921 gatccagttg ggcactattg ataatcacga tgttttcttt atcgatatcg acttgaagca
    58981 atcactcaca ggtattgatg tcgccgaaca aatacgtaaa aaaaatgcac atagtaatat
    59041 tgtttttttc accgcttata cgaattttgc agtagagatc atcaatcgga aaatccttcc
    59101 gattggatat atcagaaaag acaggaattt atctgaacaa attcgtcaag tgctagaaca
    59161 gatcaattgg aaagaacagc agatcgtaaa tgtcgataaa atctttattg atcaaaaagg
    59221 tggaagtctc gtcctgtatc ctcgggaaat tttatatatt gaaagtatca aaggtttgaa
    59281 aaaccaagtt atggtcaaaa caactacaga agataaatta gtgaatactt ctttaaaaca
    59341 attgaagaca gagttagaaa agtatgctta ctttttactt ttaaaatctt actgtatcaa
    59401 cttatcgcaa ttgcagaaaa ttgattctgc tcattatgtg ttagaatttt tcaacggtga
    59461 ctccttactc gttggtcgaa agatctttga aaagacaaag gaacgtttcc atgacttcca
    59521 aaaaactgct tcgagttgat gaataagagc tgagacgtaa gcatagcaga tttcagggag
    59581 tgggccttga atcggctcca ctccctgaaa tcgttgatat gattttacgc ttcctcttct
    59641 gtaggagcat ctgttaacga ccatgtgaat gttgaaacgt agttgtctac agcataattg
    59701 gatacaggaa caaataattc cactgattgt ctcccttgtt ccacattctc tcctaatgaa
    59761 taaatccatg tgccaatccc ttcatttgct cctgcagtta ctagatctac tgcctgatct
    59821 gctgggattt cgattccttc agcgccagtt ccagaaacgg tagatggcat tccactgcta
    59881 ttagttgcgc tatttcgaat cacggcgttt ttgaatttca cctttgaacc agttagttta
    59941 ttcgtatcag atgttgtacc aataaattct gttcgtttga ctgataattt ccaaccggca
    60001 taatttccgc ttttatccgt tacttgtacg aaattctgta cttgtgtttg tgctccagta
    60061 ctgtccgttc cgctttgtaa tgcagcatat actgtttttg ctgtacctaa cttgattgtt
    60121 ccaaaatcaa gatctggagc ttggtcaatc gtcagtaatc cggatgttcc ctgatttggt
    60181 tcgtcaggtg taaaaggagt atcaggatca tttggatcaa caggaggaac tggaacaacg
    60241 tcttcaggat ttgcagcatc tggtttggtc acagaaatcg ttccttctgt agtggctgag
    60301 ctcttattct cagcaaaaac actttgtgta cataataata gacttccagc tagaacggta
    60361 cttaatgcaa ttgttttttt catttctttt tccttctttc ttttaaaata aataatccag
    60421 caaataagcc aataagaatg actccaacaa gtatcagcca tcgccagtca aatgtttctg
    60481 gctgattttt taaatcaata tccttttcat tcaattggtc cgctgcatca tcagttattt
    60541 caaaatcggt atggagattc cagcgttttt ctttccaagc acccttcaca accgcttgat
    60601 aatgtcccgg agctaatttt tttccttcta atgggacaag taaatcaaaa tttgtattgg
    60661 gtgctacatc tattttttct ttttttattg aaaggtaagg ctcttttgtt tcttttttgt
    60721 agatttcaac cgatgtagtc aagccgaaca tataagaagc atttggattt tgaagattcg
    60781 ccttaatcac atttcttcca tcgctttgat ccgcataagc tttttttaat ttcaaatctg
    60841 gggaagactc tttttcgcta tttcaaatca agattgcttt cacttgagaa aactgattga
    60901 cgacaccaac tgtacttttg ttagaaacgt tctctttttt ttcttgaaac gtgatccctc
    60961 ctgcgaccac accagccagc tctttttctg gcgctttcag tgaaagtgtc tcagtgaccg
    61021 cactttgagg aggaacagtt atttctccca ctgtttttgc taagtttttc atatcataac
    61081 ttaatgtttc atcaaattta ctttttgatt ctccatattc gatcacaccg tttgaattcg
    61141 tcgtagcgga gtggatcaat gtctcaactg ttactgattt atctgttcgg ttaaagaccg
    61201 tgtaggggat ttcctgtgtt ttcccaggct ccatccttac atttatatat gttttgttct
    61261 tatcaatctg attagccggt aattcaaaat ctaccgcaaa attgaattcg gaggcatgga
    61321 caggtgtctg ccaaaggatg aatccaagga gaaggatcat aagtaaagag cagttgtttc
    61381 gatgactttt attccatatt cgattcatca atcatcctcc ttgatcttta ttctgtcggc
    61441 gcatctgcta atgtccatgt tatctctgct gagtaattac cagctatctg attttctttg
    61501 gttaagacaa gtttaaacgc ccgaccgtta tttaaatatt ctgaataatc tgcttgcaca
    61561 ttcgttgaat tttgtcctct gacaatttcc agttcttctt cattcactaa ttgatactcc
    61621 tctcctttct tgaaatatag gacatcctgc atagaaaatc ctgcatcatt tgtgaaaggc
    61681 tgagataatt ttatcgttaa gatccacgga tttttcgttt ctcgctgatc ataaatccat
    61741 aatttttcct gtatatccat ttggccaaat gcttcttgtg tcaaaccagt tgctttgatc
    61801 tgaccaaaat cgagtttgga aggggcaaga aatgagagac caccttctac tacgatcttc
    61861 gtagcaggtg caaaaggcgg ggcatcatga taaacaactg gcgtatcact tggattgtga
    61921 ttcccaattt catcgttggt acttggcttg ttctgcacac ccttagcagt agcttctcct
    61981 gcttggtcgt ttaatacaat ttctaataca tctcctgcaa aaagttgatt ttctgggata
    62041 gaaagaacaa attcccctgt atcatcaata gttgtttctg acaaaacagc ttgatttttt
    62101 ttcaatgaaa ccaaggctcc tgcttcacct gtacctgtga tcgtgcgaga agctgcattg
    62161 atcaatgtgg tacttaaatt agcaggttca ggaggaatca catcgactgt cgttttggca
    62221 gagtccagtt ctgtcacttc ttggccacct cttacttttt tagcagcaac aacttgcact
    62281 tgatcctccg tttttaatct ctcatcattg ggtacttgaa cttcgaacaa gccgccttgt
    62341 tcgccttctc cccatgggtt atatcctgcc ccttcatttt catctgtttg tccttgcgtg
    62401 agagcagtaa tttctacaga tgatttcgtc gtatctgcgt aagtaatacg taaagtcact
    62461 tctacttcgc ctgtccaagc atctcttggc tttgcctcga caccttcggg aacaacgaca
    62521 tgcccataga tttttttatc tgcattcgtt ggcactctta aggattcaat catcgggagc
    62581 tgattattgg cactgattcg attataattt ttcattccgg cacctgtctg agcaaattca
    62641 tttgttaaac ctgcactagg gcttgatacg aaattgccta agtcggtccc attgatcgat
    62701 aagtctgtca tatcagaaaa ataatccggg tctttttcaa agttatcgaa tgttgcgcct
    62761 gtttttcgcc ataaagcgat ttctgaatgg gcgatcttta aagaagaatc tccatttcct
    62821 tggaataccc agccgcctat gccattggtc tcgcttccaa tccgtttgtt ttggaaatca
    62881 aaataggtag gagattctaa gtccacattc aacacatccc cactgatgat gccggtctta
    62941 tcttcccctg ttttcccgac catgactaaa taagtttttt cacctgccgt aaaatttaaa
    63001 tcaatatctc cagttgtatc tacagttgct ccggaatctg cgcgtatatc gatatttgat
    63061 ttttctccag tgactgtaaa atcagctgaa cctggacttt ctagaaaacc agaagcgtca
    63121 taaaattgga tcgcttgatt tccttgattg agtctgttca cgtaagattt gccatcacct
    63181 gtatttctta ccctcaatga gcctccattg gttactgtca gcttttgcgt accattctca
    63241 aaacgaactg cgctggaacg cccactctgc ttatcgatgt cgataactga tccggctcct
    63301 tctacgatca aagaaaggcc ttttcctaca aaacgcatcc cattgttccc gggttgatcg
    63361 tcatctccag ccattttgac cgagatttgt ccaccacttg atacatggat ttgactagaa
    63421 tctccttgca agcgaaatcc gcccgtagtt gctgtattga tggtgatttt cccaccattc
    63481 gatacagtga ctttcgatcc tgaacctctc atttggatga ttccgcgatt gttgtcattg
    63541 gtaatattga tctttgtatt taccgaaaat tcgcttcccg aaccactgac ttcaaacatg
    63601 acattaccag gtagcgtatc gactgcctct ccttcatcgc taacgccatc tgcccgatca
    63661 taatcaagag agacctttga accgcttaag atatggattc ctggcgctgt ttttccacta
    63721 ccagtctcat ctcctgaatc tagaaaaccg tagaatttcc ctagatacgg tccataaagt
    63781 tgactaccat tgatcacatt caattgatag cttctacaaa aataggcttt acccggagcg
    63841 gcattcagtc cttccttcac tggttggaca tccaacacac cggaaacacc atctaatgtg
    63901 acagttgcac gaggagcgta aatcagtcct aatttggacc catcatacaa atcaagtgtc
    63961 ccggtaaatt ttatttctcc cgtaaaatga tatctgcttc cccaaaaatc ggtcatataa
    64021 gcaatgataa tggcatttcc atcgatattt ggtgtcaatc cacctggatg tgcagctgtt
    64081 cctttaaaat tctggaactc gatcgactga ggtatctcat tgatataaat atggtgtgtg
    64141 ccgaaattgt gagcgaatcc accaaaatca ataacgatat ctcgtttgat ctctaattcc
    64201 ctgtctaaag tcaaaggctg aatcagtcgg atcttagtta ctgattcgtc tgcgagaagc
    64261 tgcgccagtt cttctgttgt ggcagcttcg ctgtacccat ccgctgaaac agctcttgcc
    64321 agtgccgctt cactgctatc agacgtttgt tcagctactt ctgaggtctc acttgtctta
    64381 ttttcttctt gccttttatt agtagaagcc tcactttgag attctgtagt ttcagaagta
    64441 atcgattctt ctgaaaaagt agtcttgtca aaactttgat tctctgattg cgttgattcg
    64501 tttgttttct ctacatcggc aaaaacggat gtcaccatca agagagggaa gacaaacaaa
    64561 atcgacgcaa tcagcttttt tacacattga ttcattctcc accatcctct ctgacgtttt
    64621 gacaatttta ttttatcgtt ttaatctatt tccaattgta ctttcatatt taaaatatgt
    64681 atttttatgg aaaaattttt ctattaggtg taaatttctt ttttgtac
//
LOCUS       DASHXG010000010        59230 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.010, whole genome shotgun sequence.
ACCESSION   DASHXG010000010 DASHXG010000000
VERSION     DASHXG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.010"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(451..1761)
                     /locus_tag="U2R59_000781"
     CDS             complement(451..1761)
                     /locus_tag="U2R59_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEM8965194.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="U2R59_000782"
     CDS             complement(1773..3191)
                     /locus_tag="U2R59_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8965195.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="U2R59_000783"
     CDS             complement(3431..4999)
                     /locus_tag="U2R59_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEM8965196.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="U2R59_000784"
     CDS             complement(5003..5413)
                     /locus_tag="U2R59_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HEM8965197.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="U2R59_000785"
     CDS             complement(5410..6333)
                     /locus_tag="U2R59_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HEM8965198.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="U2R59_000786"
     CDS             complement(6330..7208)
                     /locus_tag="U2R59_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HEM8965199.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="U2R59_000787"
     CDS             complement(7195..8532)
                     /locus_tag="U2R59_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HEM8965200.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="U2R59_000788"
     CDS             complement(8535..9638)
                     /locus_tag="U2R59_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEM8965201.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="U2R59_000789"
     CDS             complement(9712..11220)
                     /locus_tag="U2R59_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8965202.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="U2R59_000790"
     CDS             complement(11186..11878)
                     /locus_tag="U2R59_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEM8965203.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="U2R59_000791"
     CDS             complement(11900..12874)
                     /locus_tag="U2R59_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965204.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="U2R59_000792"
     CDS             13174..14046
                     /locus_tag="U2R59_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965205.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="U2R59_000793"
     CDS             complement(14504..16702)
                     /locus_tag="U2R59_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965206.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="U2R59_000794"
     CDS             16934..17926
                     /locus_tag="U2R59_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965207.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="U2R59_000795"
     CDS             17986..19407
                     /locus_tag="U2R59_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HEM8965208.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="U2R59_000796"
     CDS             19400..20899
                     /locus_tag="U2R59_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HEM8965209.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="U2R59_000797"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="U2R59_000797"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEM8965210.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="U2R59_000798"
     CDS             22491..23174
                     /locus_tag="U2R59_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HEM8965211.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="U2R59_000799"
     CDS             23176..24012
                     /locus_tag="U2R59_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEM8965212.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="U2R59_000800"
     CDS             24023..25777
                     /locus_tag="U2R59_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965213.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="U2R59_000801"
     CDS             complement(26053..26394)
                     /locus_tag="U2R59_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8965214.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="U2R59_000802"
     CDS             complement(26462..28633)
                     /locus_tag="U2R59_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEM8965215.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28802..29701
                     /locus_tag="U2R59_000803"
     CDS             28802..29701
                     /locus_tag="U2R59_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8965216.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="U2R59_000804"
     CDS             complement(29772..30629)
                     /locus_tag="U2R59_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8965217.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="U2R59_000805"
     CDS             complement(30614..33316)
                     /locus_tag="U2R59_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEM8965218.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="U2R59_000806"
     CDS             complement(33329..34618)
                     /locus_tag="U2R59_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEM8965219.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="U2R59_000807"
     CDS             34768..35814
                     /locus_tag="U2R59_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965220.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="U2R59_000808"
     CDS             35816..37969
                     /locus_tag="U2R59_000808"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEM8965221.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="U2R59_000809"
     CDS             complement(38442..39893)
                     /locus_tag="U2R59_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965222.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="U2R59_000810"
     CDS             complement(39890..41614)
                     /locus_tag="U2R59_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8965223.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="U2R59_000811"
     CDS             complement(41607..42221)
                     /locus_tag="U2R59_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEM8965224.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="U2R59_000812"
     CDS             complement(42566..44023)
                     /locus_tag="U2R59_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965225.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="U2R59_000813"
     CDS             complement(44064..44984)
                     /locus_tag="U2R59_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965226.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="U2R59_000814"
     CDS             complement(44996..45943)
                     /locus_tag="U2R59_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965227.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="U2R59_000815"
     CDS             complement(46422..47141)
                     /locus_tag="U2R59_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEM8965228.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="U2R59_000816"
     CDS             complement(47190..48836)
                     /locus_tag="U2R59_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8965229.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="U2R59_000817"
     CDS             49015..49605
                     /locus_tag="U2R59_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8965230.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="U2R59_000818"
     CDS             49697..51202
                     /locus_tag="U2R59_000818"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEM8965231.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="U2R59_000819"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="U2R59_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEM8965232.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="U2R59_000820"
     CDS             complement(52638..53156)
                     /locus_tag="U2R59_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965233.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="U2R59_000821"
     CDS             complement(53172..53498)
                     /locus_tag="U2R59_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEM8965234.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="U2R59_000822"
     CDS             complement(53511..55490)
                     /locus_tag="U2R59_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8965235.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="U2R59_000823"
     CDS             complement(55511..55825)
                     /locus_tag="U2R59_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEM8965236.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="U2R59_000824"
     CDS             55993..56286
                     /locus_tag="U2R59_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEM8965237.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="U2R59_000825"
     CDS             complement(56364..57476)
                     /locus_tag="U2R59_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8965238.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57863..58042
                     /locus_tag="U2R59_000826"
     CDS             57863..58042
                     /locus_tag="U2R59_000826"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965239.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="U2R59_000827"
     CDS             58236..58406
                     /locus_tag="U2R59_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8965240.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFPTPFKEA"
     gene            complement(58830..>59230)
                     /locus_tag="U2R59_000828"
     CDS             complement(58830..>59230)
                     /locus_tag="U2R59_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8965241.1"
                     /translation="GEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLV
                     ETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKT
                     GETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17748 a        12069 c        10347 g        19066 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg acgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgcct caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttctaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcgct tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 ttcccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc
//
LOCUS       DASHXG010000011        56666 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.011, whole genome shotgun sequence.
ACCESSION   DASHXG010000011 DASHXG010000000
VERSION     DASHXG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.011"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..498)
                     /locus_tag="U2R59_000829"
     CDS             complement(<1..498)
                     /locus_tag="U2R59_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965242.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGF"
     gene            complement(769..1314)
                     /locus_tag="U2R59_000830"
     CDS             complement(769..1314)
                     /locus_tag="U2R59_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8965243.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(1326..2018)
                     /locus_tag="U2R59_000831"
     CDS             complement(1326..2018)
                     /locus_tag="U2R59_000831"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEM8965244.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(2037..2321)
                     /locus_tag="U2R59_000832"
     CDS             complement(2037..2321)
                     /locus_tag="U2R59_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965245.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(2334..2897)
                     /locus_tag="U2R59_000833"
     CDS             complement(2334..2897)
                     /locus_tag="U2R59_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8965246.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            3125..3787
                     /locus_tag="U2R59_000834"
     CDS             3125..3787
                     /locus_tag="U2R59_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HEM8965247.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3911..5107
                     /locus_tag="U2R59_000835"
     CDS             3911..5107
                     /locus_tag="U2R59_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEM8965248.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(5208..6584)
                     /locus_tag="U2R59_000836"
     CDS             complement(5208..6584)
                     /locus_tag="U2R59_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965249.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(6621..7487)
                     /locus_tag="U2R59_000837"
     CDS             complement(6621..7487)
                     /locus_tag="U2R59_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HEM8965250.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(7576..8601)
                     /locus_tag="U2R59_000838"
     CDS             complement(7576..8601)
                     /locus_tag="U2R59_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8965251.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(8619..9293)
                     /locus_tag="U2R59_000839"
     CDS             complement(8619..9293)
                     /locus_tag="U2R59_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965252.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(9477..10370)
                     /locus_tag="U2R59_000840"
     CDS             complement(9477..10370)
                     /locus_tag="U2R59_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8965253.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(10444..12141)
                     /locus_tag="U2R59_000841"
     CDS             complement(10444..12141)
                     /locus_tag="U2R59_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8965254.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(12134..13447)
                     /locus_tag="U2R59_000842"
     CDS             complement(12134..13447)
                     /locus_tag="U2R59_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEM8965255.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(13447..17484)
                     /locus_tag="U2R59_000843"
     CDS             complement(13447..17484)
                     /locus_tag="U2R59_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEM8965256.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(17497..17955)
                     /locus_tag="U2R59_000844"
     CDS             complement(17497..17955)
                     /locus_tag="U2R59_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8965257.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(18253..18771)
                     /locus_tag="U2R59_000845"
     CDS             complement(18253..18771)
                     /locus_tag="U2R59_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEM8965258.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18773..19389)
                     /locus_tag="U2R59_000846"
                     /pseudo
     CDS             complement(18773..19389)
                     /locus_tag="U2R59_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(19386..20249)
                     /locus_tag="U2R59_000847"
     CDS             complement(19386..20249)
                     /locus_tag="U2R59_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965259.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(20236..21147)
                     /locus_tag="U2R59_000848"
     CDS             complement(20236..21147)
                     /locus_tag="U2R59_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965260.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(21188..22522)
                     /locus_tag="U2R59_000849"
     CDS             complement(21188..22522)
                     /locus_tag="U2R59_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965261.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22730..23560
                     /locus_tag="U2R59_000850"
     CDS             22730..23560
                     /locus_tag="U2R59_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HEM8965262.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWCGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23804..24122)
                     /locus_tag="U2R59_000851"
                     /pseudo
     CDS             complement(23804..24122)
                     /locus_tag="U2R59_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(24244..24438)
                     /locus_tag="U2R59_000852"
     CDS             complement(24244..24438)
                     /locus_tag="U2R59_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965263.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24943..25128)
                     /locus_tag="U2R59_000853"
     CDS             complement(24943..25128)
                     /locus_tag="U2R59_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965264.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25978..26319)
                     /locus_tag="U2R59_000854"
     CDS             complement(25978..26319)
                     /locus_tag="U2R59_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8965265.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(26319..26549)
                     /locus_tag="U2R59_000855"
     CDS             complement(26319..26549)
                     /locus_tag="U2R59_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8965266.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26836..27174
                     /locus_tag="U2R59_000856"
     CDS             26836..27174
                     /locus_tag="U2R59_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965267.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(27379..27618)
                     /locus_tag="U2R59_000857"
     CDS             complement(27379..27618)
                     /locus_tag="U2R59_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEM8965268.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(27594..27941)
                     /locus_tag="U2R59_000858"
     CDS             complement(27594..27941)
                     /locus_tag="U2R59_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HEM8965269.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(28673..29254)
                     /locus_tag="U2R59_000859"
     CDS             complement(28673..29254)
                     /locus_tag="U2R59_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965270.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(29437..30063)
                     /locus_tag="U2R59_000860"
     CDS             complement(29437..30063)
                     /locus_tag="U2R59_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8965271.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(30085..31416)
                     /locus_tag="U2R59_000861"
     CDS             complement(30085..31416)
                     /locus_tag="U2R59_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEM8965272.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(31571..31972)
                     /locus_tag="U2R59_000862"
     CDS             complement(31571..31972)
                     /locus_tag="U2R59_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEM8965273.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(32058..32264)
                     /locus_tag="U2R59_000863"
     CDS             complement(32058..32264)
                     /locus_tag="U2R59_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965274.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(32359..33861)
                     /locus_tag="U2R59_000864"
     CDS             complement(32359..33861)
                     /locus_tag="U2R59_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HEM8965275.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(33879..34334)
                     /gene="argR"
                     /locus_tag="U2R59_000865"
     CDS             complement(33879..34334)
                     /gene="argR"
                     /locus_tag="U2R59_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEM8965276.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(34432..35049)
                     /locus_tag="U2R59_000866"
     CDS             complement(34432..35049)
                     /locus_tag="U2R59_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HEM8965277.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            35270..36643
                     /locus_tag="U2R59_000867"
     CDS             35270..36643
                     /locus_tag="U2R59_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8965278.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            36718..37830
                     /locus_tag="U2R59_000868"
     CDS             36718..37830
                     /locus_tag="U2R59_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEM8965279.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(37902..39539)
                     /locus_tag="U2R59_000869"
     CDS             complement(37902..39539)
                     /locus_tag="U2R59_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HEM8965280.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(39707..40315)
                     /locus_tag="U2R59_000870"
     CDS             complement(39707..40315)
                     /locus_tag="U2R59_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8965281.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(40699..41850)
                     /gene="queG"
                     /locus_tag="U2R59_000871"
     CDS             complement(40699..41850)
                     /gene="queG"
                     /locus_tag="U2R59_000871"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEM8965282.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(41869..42621)
                     /locus_tag="U2R59_000872"
     CDS             complement(41869..42621)
                     /locus_tag="U2R59_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965283.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(42762..43712)
                     /locus_tag="U2R59_000873"
     CDS             complement(42762..43712)
                     /locus_tag="U2R59_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEM8965284.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(43713..44552)
                     /locus_tag="U2R59_000874"
     CDS             complement(43713..44552)
                     /locus_tag="U2R59_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEM8965285.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(44549..45295)
                     /locus_tag="U2R59_000875"
     CDS             complement(44549..45295)
                     /locus_tag="U2R59_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEM8965286.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            45533..46903
                     /locus_tag="U2R59_000876"
     CDS             45533..46903
                     /locus_tag="U2R59_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965287.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(46958..47854)
                     /locus_tag="U2R59_000877"
     CDS             complement(46958..47854)
                     /locus_tag="U2R59_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8965288.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(47968..48138)
                     /locus_tag="U2R59_000878"
     CDS             complement(47968..48138)
                     /locus_tag="U2R59_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965289.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(48135..48812)
                     /locus_tag="U2R59_000879"
     CDS             complement(48135..48812)
                     /locus_tag="U2R59_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEM8965290.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(48903..49808)
                     /locus_tag="U2R59_000880"
     CDS             complement(48903..49808)
                     /locus_tag="U2R59_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEM8965291.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            49983..51437
                     /locus_tag="U2R59_000881"
     CDS             49983..51437
                     /locus_tag="U2R59_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8965292.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            51453..52484
                     /locus_tag="U2R59_000882"
     CDS             51453..52484
                     /locus_tag="U2R59_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8965293.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            52491..53678
                     /locus_tag="U2R59_000883"
     CDS             52491..53678
                     /locus_tag="U2R59_000883"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEM8965294.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            53834..55216
                     /locus_tag="U2R59_000884"
     CDS             53834..55216
                     /locus_tag="U2R59_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8965295.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            55343..55573
                     /locus_tag="U2R59_000885"
     CDS             55343..55573
                     /locus_tag="U2R59_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965296.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(55773..56441)
                     /locus_tag="U2R59_000886"
     CDS             complement(55773..56441)
                     /locus_tag="U2R59_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEM8965297.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        16302 a        11835 c        10025 g        18504 t
ORIGIN      
        1 aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg cccgcatcct
       61 aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg atccgcttga
      121 ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta atggttcaat
      181 ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact cttcatttgc
      241 ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag gatcatttcc
      301 ttcttccgta tccatatctt cactagttct tggtatttcc tccattgttg acatcccttc
      361 aatgttcacg tgtgcatttt cttcgttcac agactgttgt tcgttagcag caacttcaac
      421 gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg cactgtattt
      481 tatacgtttt tttaacaagt gtattcctcc cgtaacaaat tagaaagcgt ttacttaaag
      541 tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt gtattttata
      601 aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg gaaaaagaat
      661 aagttttttt aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg ttttatgctc
      721 ttcttttatt attttgtgct ttttatttta tcaaatcact ttgttttttt ataaaatttc
      781 tgcgcctagt gtggactcaa aatgtctcaa tgcccattca tgtccaacgg gatcgaaact
      841 tgccacggaa tctttgaaaa tatggagttt gtatcctaga ttatacgcat cgactgctgt
      901 atgcaacaca cagatatctg tacatacgcc ggtcaaataa atatctgtga tctggcgttc
      961 tcgcaaacgg atgtctagat ctgttccact aaaagcggaa taatgccgtt tgtctatcca
     1021 ataaacattt tcctcttgct catagtcttg gtataaactt tttaaagagc cgtacaattc
     1081 ccgtccaccc gttcctatca cattatgcgg aggaaataag cggttctccg gatgaaagga
     1141 atcttttgga tcatgcgcat caatggcaaa aacgacaaaa tccttttgat caataaactt
     1201 ctttgtatga gcagtcagct ttttttcaat tacttgtcct gctgtcccag tagtcagctt
     1261 tccatcctct gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt tcatcttagt
     1321 cctccttata cgagatgttt gacaaattcg atcaccattt ctgctgatcg tttgcctgcg
     1381 tcttcgataa attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca
     1441 cgtacgatca aaaatgggat attgaactga cgagctgttt gtccaacagc ggctccttcc
     1501 atttcgcaag ctaatgcttc agggaaattc gttaagattt ctttgatttt atctggcgag
     1561 tcgacaaatg tatcacctgt aacgatcaat ccttcttttg cgttcaaatt cgttgctttt
     1621 gctgctttaa ccatttcact gcgcaaatat gtgcttgctt cataatatag aggcattcct
     1681 ggtaattgtc ctgggttgta gccaaatcct gttgcatctg catcaaaata agctactttg
     1741 tctgatataa cgatgtcacc tacttgtaag ccttcaccga ttccgccagc tgaacctgta
     1801 ttgatcacca tgttcacgcc gtattgttgg atcaacagac ttgtggtaat agatgctaag
     1861 acttttccta taccggaacg tacgacgatc acttcgtggt tacctaatga acctgaaata
     1921 aataaagcgc ctgcgcgttc ccatgataat ggttcgctta ggttctctct caaaattttt
     1981 acttcttctt ccattgcgcc gataataccg attttcatct ttttaattcc ttctttctat
     2041 ataaatgcga ttgctaaaaa aaccacacat aacattagga taacaataat aagagatttc
     2101 atcaaaaaag agttccattt ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt
     2161 ggtttattct ttttgctttc tttacgataa aagctggcaa tctttttttc ttcttgctga
     2221 taagctgttt ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc
     2281 ttgcgaagtt cgcttcgcgt aataagcggt cctttggcca taagccgatc cctctacttt
     2341 cctttggtca atagttccca gtattgaatc gcataaatcg tctttgcatc acaaatcaac
     2401 tgatctttca tcgcttgttg cgcctcttca agagttagat gatacaactc cagtacttcg
     2461 tcttcatctt gtgctaaagg attctcgacc ttctctaccc cttgtgcatg ataaatatga
     2521 aggacttcat ttgcaaaacc tggtgaaaga tacatcgaag taagatggct cagcgacttc
     2581 gcacgatagc cagtttcttc ttctaattct ctagctgctg tcatttcggg attttgtcct
     2641 tctcctggat cgatttttcc agctggaatc tccaaaatca ctttttctaa aggttttcga
     2701 aattgtttga caagaagcag acgatcttgt tcgtcaaaag caatgatccc gacaccgcca
     2761 ggatgaaata ccagttctct cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca
     2821 gcaacatcaa taatttttcc gctatagatt tctttgcgac tgattgtttt ttcttcaaat
     2881 tgctcattgt tcagcatatc ttctcctgct ttctttgtaa tcataactgc ttttttttca
     2941 tttttcaatt tttctcaaaa actccttatt agtttaccat agataaacct tagattttct
     3001 ctaaatatag aaaatccttc tttagtccga tactctttct agtagtccgt atgctaaaat
     3061 aagtatgtaa tcgaataacg aaaagaattc aatactcaac gataaatgac atggagggtt
     3121 tattatgata aaacgaaatt ggccgtggct tctagcattg gtcttgctat ttctctttgt
     3181 ccgaaacaat agtttttctt ttgttctagg acttttattg ataggtgtag ttttagtttt
     3241 gtggggactc tttggttcgc gcaggaaaaa gggaaaacaa gaagaaattc ctgcactgac
     3301 tgacgaactt gaaactcact atgaaaaaag cggtatgaca gcgaatgaaa tttcattttt
     3361 tcgacaaaca atgaatcaaa caaaaaatga gatcaatcaa ttgcaaatga atatgcagca
     3421 gacagccaaa cttaaagcaa tcgatctccg ccatgatcca gtcaaagcag cgaaagcttt
     3481 attcaaagaa ttggtgaaag aaccaaaccg actgcatgaa gcaagtcagt ttctttatac
     3541 gcatctgccg aatctagttg atttgacaaa taagtataat gagatcaatg accatgagat
     3601 caaaaacaaa cagacctatg aaaaactaga agaaagcgcg cagatcatcg accagctgtc
     3661 agctttaatc gcacaagatt atcaaaaatt cgttgctgag gatctagatg atatcgacgt
     3721 agagatatct gttgcgaaac agagcttaaa gcgtgataat aaatatgaac cagaacaaaa
     3781 ggattaactc ttttgttcat aaaagaagac tcggaacatt cagatgatgt ctggctgttt
     3841 cgagtacttt ttctaaagta gagacattca tgtaagaatc gagaacagat tcaacaagga
     3901 ggaatttttt atggatcata aaccgactga aacaaaagat gttacaccag ttaacgatac
     3961 acttgaagat ttattgaaca acccgttttc aactccaaca gatacgctga ccacttcaca
     4021 acaagcggag attgatcagc tccaagagca acagacagct gctcgtttaa ttgacaaact
     4081 accggcggaa cgccaagaac aagctaaaca gctagcagca aaaatcgatg ctaatgatgc
     4141 acagtctgtc atcagctacg gatcggctgc ccaagcaaaa ttaagtgaat tctcacaatc
     4201 gatgttgaat catgtgcaag cacaagatat tggtcctgta ggagattcct taactgaact
     4261 gatgtatcgt ctccaagaag ccaatcctga cgaactgcgt gccggagaag ggaacatctt
     4321 ccagcgtgtc ttcgggaagg tcaaacaatc gatctatgaa gtgacagcaa aatatcaaaa
     4381 gattggtgca caaattgaca agatttcagt gaaattagat aaagaaaaag acggtctgct
     4441 aaaagataat ctgatgttag aacagcttta ccagaaaaac aaagactact ttgatgcact
     4501 gaatatttat atcgctgctg gagaattgaa aatggaagaa cttcaaacaa cgatcattcc
     4561 agaagcgatg aaaagagcag aagaaactgg cgatcagatg gatgttcaga ttgccaatga
     4621 ttacacgcaa ttcctagatc gtctggataa acgtacgcat gatcttcgct tagctagaca
     4681 gatcacgatc cagcaagcac cacaaatccg tttgatccaa aacacaaatc aggccttggc
     4741 tgaaaagatc caagcatcta tcgctacagc cattccgctg tggaaaaacc aagtcgtgat
     4801 cgcattgacc ttgcttcgtc aaaaagatgc agtaactgct caacgccaag tctctgaaac
     4861 aacaaacgac ttattgaaga aaaattcaga aatgctgaaa atctcagcca tcgaaacagc
     4921 gaaagaaaat gaacgtggaa tcgtggatat cgagaccctt caaaccactc aaaatgattt
     4981 gatcgaaaca atccaagaga cattgcgtat ccaaaaagaa ggaaaagaaa aacgtcgtca
     5041 tgcagaagta gagcttggac acatggaaga agatctgaaa caaaaactgt tggatttaac
     5101 ccaatagatc acctttcgct tgttactaaa acaaacgccc aacaacagtt tattacaact
     5161 gttgatgggc gtttttctta tctttcttct aacttctcca ttggagtcta tttctcattc
     5221 atcttgctgt gtccatagcc atagccaaaa taaatgatca gtccaataac cattacgata
     5281 ccgaacacga tccatgtcac agtttgcaga cgaagcatca atacaataca agtcaagatg
     5341 gagacgattg gcaatagcgg aacgaatggc actttgaatt ctccagcttt tggtttgcca
     5401 aacatttttc tcaacttcag taagcctaga ctaacaagca tcaaataggc gagcgccatg
     5461 atattcgtta gttccgctaa tacattcaat gggaaaaatc cggcaaagaa tacagctgcc
     5521 acaccagcgg cataagtcgc ttttttcggt gtacgatgct tttgatcgat ttctgtcata
     5581 aacttaggaa gtaagccatc cttgctgaca gcaaacagta aacgagcaag tgaatacatc
     5641 atcgagatcg ttaccgtcag tagcgttaaa attgccccta cagcgatcac cgcgcccact
     5701 gttccatgtc ctacatacct cattgcaaaa gccactgggt cattgactcc tagttcagta
     5761 tacggaacga ttcctgtcaa gatcagcgtc acgatgatgt aaaggacagt agcaatcagt
     5821 atcgaaccaa tgattcctct tggcacatct ttttgcgggt ttttgacttc ctcggctgcc
     5881 attgcaacgg catcaaatcc caagaaagca aaaaacacaa gagctgcacc atctagcaca
     5941 ccggaaaaac caaaaggcat gaatggctgc cagttatcag gtttaacgaa aaatattcct
     6001 acaatgataa acaacgcgat gataccaaat ttgacatata ccatggcatt attcaaacgt
     6061 aatgctttct tggcttcaag cgacacgatg taagtgacga atatcactac gagcaccgca
     6121 atcaagtcaa tgtatgtacc attttccgga ttgtacccgc cagttaatgc ttgtggaagt
     6181 tcggccccta aacttttcaa aaaaccttgc atatagccag accatccgga agcaacagag
     6241 gaaaccgcta gtaaaaattc cccgatcaac aaccaccctg tcagccaggc agcaaattca
     6301 ccaaatacaa catacagata ggcatatggc ccaccaatca ctggcactcg cgaagcaaat
     6361 tctgcgaaac ttagtccaga caaaatgaca acgattgcag ctaagacaaa tgaaagtgac
     6421 agtgctggac cagcattttg attggccgca acccctgtca ccacaaatat tcccgtaccg
     6481 atgatcgcac caattccaag catgatcaaa tcagacgttt ttagttcttt tttcatctca
     6541 ctcgtatgat tgagattgat ctctttctta cgaaacaaat ccattgaagt tcctccccat
     6601 tttaggttgg aaaacagcga ttaaactgtt ttcatatacc ctaaaaggat accacctaaa
     6661 atgactaaaa ggcaaccaac aataacataa atgagctctt ttttcgtttt tctttcgcca
     6721 aggatgaaaa tcccacctaa agtagagata atgatcccca tttgtgaaag tgagaagcca
     6781 acagctaaac caagtgattt gactgttaga agcatgcaga tgtttcctaa gccccataat
     6841 aatccacaga tcatgttttt ccacacaaac tgatcgactt taactttacg gaaagcaaag
     6901 aagcttgcgc ctaagatcat tccgatactt tgaggtaaga taattgacat cgcatccaaa
     6961 ttcgcccagt tgacgatgat ggtatataca ccataaccaa tcgtagagaa gatcaatgct
     7021 ctaaaaccct taccaaaatc aagcatttta ttatctgtat ctatttttcc ttcgtcatct
     7081 tgtcgggcag tcaaatacgc accgcttaca agaagagcta aagcaataat accgtataca
     7141 taatctttcg tttgtgtcca ttcatggaag aaaacggctc ccgcaatcgt attcaaaatt
     7201 aattgaaaac cagtagacaa tggtagccct acagaaacac ccatgtactt cattccatgg
     7261 aactgtccat tttgtccaac actccaagct aagccggata aaaatccgat caagaaaatc
     7321 caaggggtga ttacaggact aacaacgaaa aagacaacta aagaaaacag aaatgcaccg
     7381 atcgtcattc ctagtgtttg ttgattggca tcgccaccaa ttttaccact tactaaacca
     7441 atactacccc atgccaacat agggactaat gctattaaaa tttccataac caatctcctt
     7501 ttatttcaca tgataagaaa cttatcagcg aaaacgttaa caacacaagc actttttttc
     7561 gtttctaacg attttctaac gtttttcatt ataaaaattt aagattggga aaaataaagt
     7621 cattgttgtc ccttttcctt cagttgattc agccgtcaaa tggataccta atttttcggc
     7681 cagatttttt gctaaataaa gtcctaatcc tgttgaatgt gttttgctaa gtcgaccatt
     7741 tctcccagta aatcccttat caaagatccg tttcaagtct tccgctggga taccgatccc
     7801 tgaatcttta actgaaaggc tgactccttg cgcttccttt tctatgctca caatgatgtt
     7861 tccgtgatcc ggcgtatatt tgatggcatt actaagcaat tggttgaaga taaaagcgat
     7921 ccatttagca tcggtcaaaa cagtatgatc ctcaccaacg atctcgtagc gaatattttt
     7981 ttggataaaa taatttgcct gactgcgtat cacaggctga atgattcctt ttagtccata
     8041 ttcttggatg aggtagtccc gcgagaaact gtcgagtctt gcataataca aaacttgttc
     8101 tacgtattca tcgatttttg ataattcatt ttctagtaat gtatactttt gatcgtcaat
     8161 atcgaactcg atcgaacgaa ctagcaattt agaagcggaa agtggcactt tgatttcatg
     8221 gacccatgag tcaatataat ctttttggtc ttgttgatta ctgattgctg attgcattac
     8281 ttcttggtgt tcacggatca gctgattgat atattcttct accagttttt cttcttctgt
     8341 cctcccacca ctcaaataat tttgcaaagg ggaagttttt tgtatgtcgg ctaattttcc
     8401 ccaccatctt ctcttgctca agtaaccacc cagcagataa aaaatcagaa agacgccctc
     8461 aatcaaagct aaataagcaa ttgtgctcaa atcaactttg atgtttggcg ccagccacat
     8521 cacaaagatc gtcaatgcaa taaaaaacag ccatcccaag atcaatgtcc actgatcttt
     8581 caaatattta aaaaaattca tcttaaccgc tcatcctttc agggaacgat atatccctgt
     8641 cctacttttg tttcgatata tccttggata cctgcctgtt cgatttttcg gcgtaaccga
     8701 ttgatgttga ctgtcaatgt attgtcatct acaaatcgtt cgtcatccca cagtgctcgc
     8761 agcaattttt cccgacttaa gatctttcca ttgtgcttca tcaaaataaa taatagacga
     8821 tattcatttt tgctcaaatc aatgatctct ccgttgattt ccatacttcc gttgtcaaca
     8881 ttcaacgtaa tgccattgtg gctcatcatt tcactagata attctgtgta gttgtaagaa
     8941 cggcgaagta atgcattgat ttttgcaatc agtacatcga tttggaaatg ttttgtcaca
     9001 aaatcatctg cccccatgtt catagccatg atcatatcca tattcgtatt cctgctggag
     9061 ataaaaatga tcggtacttt cgatacttca cgtatttttt gacaccaata atagccatcc
     9121 aaaacgggaa gattaatatc tagtaataca agctgtggtt cttctctttc aaagtctgag
     9181 aacacttgat tgaaatcggt cgttccaaag gtttcaaatt gccatttctc aagttcctcc
     9241 atgatcaatt gtcgaatgat ctcttcgtct tcgactacca tgatttttgc cataaaaaat
     9301 ccctccatct ttcttcttgc tactacaata tcaaagaagc ccttgtgaaa caagttggct
     9361 tacctggaaa atgtcatttt agcaaacgtt aaaaaaaact ggaaatatgc gatttaatcg
     9421 cgtttgtctc ttccaagcag cttaaattta ttatgttatt cttaataatt ggtctattat
     9481 ctgttatttt tctttcgttg tttttgtctt ttaaattttc gataacacca ataaccgaaa
     9541 agcgttagca ctagcaatat acctagaagg agtataagta atcgataaag atggtatttt
     9601 tttgtctgtt ctatctttga agagacttct tctgtaaagg gaactcgtct tcctgtcact
     9661 agtaatcggt gagtgttcac ggtgtaaggt gtacaagtga taagtgtgac tagatcctgc
     9721 ttttctctaa ttgctaatgt atttgttttt gttggaagga caacaatttt ctcaacgact
     9781 tcataagcga gcatccgacc atacacttca agatagaatc ggtcatcttg ctccatttct
     9841 tcaagatccg taaagagttt tttctcagca ataccgctat gggcggtaat cacggaatgt
     9901 gtactctctc ctccagttgg aaaagaggtg ccttgcagga ctgtcgctcc tctatctaac
     9961 aaaagatcat tcgtttcatc aaataaaggc aagctaacat tgattttcgg aatatagatg
    10021 gctccgatca tatgttgttc gtaatattct tttcctggat tttggacatt tctaaccgct
    10081 tgctcaaaag gatctttgac ttgtcccatt cctgggatta ctgatgtatg agcaagcgtc
    10141 tgatttttct tttcatgcac tgctaattgt tgctcatgtt tttcttcttt atcgcgttca
    10201 agctgctttt gataattctc gatccttctt tgatccaaat aattgctgag agcatctgct
    10261 aaaaatggat atgtaaaaac tgcagctccg gcaagaaaca tcactgccat aaataattgt
    10321 aataaaagac tgatttgggt ttgaggtcta ttacctattt tctttttcat tttcttcacc
    10381 ttcttattta aaaaaactgc agcaaccttt ataaaaccga ttgctgcagc ttatttttgt
    10441 tgcttatact tcagacttca ttttagattt acggtaccag ctgtacgctc caatcatcaa
    10501 acttattccg attagtaaga atgccaagag cccgttccca ccagtagcag gaagtgaccc
    10561 gcgtttcata ttcggtactc tttctggccc tggattttct actcctacga tctgaatttc
    10621 ttcattatag cttccataag agatgataaa ttcagtaaag gctgcctcac ctgttggaag
    10681 tacataacct tctggcgcca tggtctcttt catttgatag gttccataat ctaacccttg
    10741 aacctcaaag tatccatttc catctgcgac aaattctgtt gcttgtccgc ttgttgccca
    10801 ctcaattcta tctgctcctg attcataaac agctaaaggc gactcccctt tataaaatat
    10861 tgcgtattca gaacggtctt cattccacaa ttcgaatctt gcatctttaa gcaattcact
    10921 gcttgatgca tcatattttt caaactttct tccacctgtt gtgactttct ctggcggctc
    10981 tactccttct tcataatcaa attcatcatt tcgtccgatt tcaataaccg ctgtgttgtt
    11041 atggaaatca tccgcttcta gttctgtgga aaccttcaaa ttatacgtga tcgttaaatc
    11101 tcctccacgt gcatctgcta atctacctaa agtatctact ttggctactc cattttcttc
    11161 tgtcaaaatc gtcacgacaa acccgttgct tactacttct actatataat cttgtccttt
    11221 tgttaaaatc gtctcgccgg ctcgcacttc tatttcctga tcataataag ttagaccaac
    11281 tgtaggcgta tctgtgattt tgtaattttt gataacagcg cttccgtttt caaggacaga
    11341 atcgatgaaa taaggaatag gtgctgtgat cgtgtaagaa gccgtttttc ctctttctag
    11401 atcaatataa gaaatcgttt cttgttctcc agcttcatta ataatcgtta cttgtctaag
    11461 gtcgctttcc tctacattca tctgtttatc tgcttctctg atttcgtttt tcggatacaa
    11521 atgcacatct gtattgtatg tgtctttcca tgtagaacca tcccacacgc catccaccat
    11581 atcaggcatc atcactggca tcataacaac cattggagac gcgattctgg aaatatgagc
    11641 tggcgaataa gtttctaaga aaagatagac tttatctcta gaagaaggtg cttcttccgt
    11701 cacttggacg gtagagaata ccgcttctcc agcttcattc gttgtttgtt tgtcaatact
    11761 tgtcagtcga tattttaaaa accaactttc tgtgtgccgt ttttgaatcc attcaatcgc
    11821 ttcggcagaa ttaagaccgt cttctcgttc cggtgttaaa ggattatctc gaatcaaatc
    11881 gtaatatact tccgttacgt caaacaaatc aaaatcgact cctggaatat tttcttcacc
    11941 aaaatccgta gaaaccaatc cgctattcgg tcgttcttcc ggaacagatg agaaaccttt
    12001 tttgtgtaat gtaatcgtca cttcacttgg tttttgtgcg acttcttcgg ctttgactag
    12061 ttttccgttc ccgaaaatcc ctattcccgc agtaacgagt aacagtacac tcattcccgt
    12121 gacaatcatt tttttattca tttttttctc cccgttcttt ttttattaat aaaacagcac
    12181 ctaacaataa aagaattcct agtaaagaaa tcaacgttct tgcttcattc gtttgcggga
    12241 atacggacca ttttcctgat tgacctggat tgcttggacc actcggctct ttcggtttgt
    12301 ccgttgtttc ttttacggtc tcgttataaa cacgtggtgt tgcggattca taggcagaga
    12361 ctggaacttt cccggattct aattcagcca tctcctgtcc gttaactact acatattgtg
    12421 gttggccttt tgcatccacc caaaattcag ggatgatgac ctcgattctc ttacttgctt
    12481 catccatctc gtaaccttcc acacctttta attcttcaaa ataataggtg ccagaaggca
    12541 agaaacgttg tcctgtcgta acaaggccct ctttatccga aatgaatttg cttacatttt
    12601 tgtcattcaa aggatcattg tctgctggtt tgatccattg atttttcaag tcattagcag
    12661 gagccatatc taaataatat ttcccccctt ctatcatctg atatagagca aaaacagcac
    12721 cttctaatgg ttttcctttt tcagttgttc ctctttgacg tccatacttg aagaagtatg
    12781 gatctcttag ataaccgaca tttttaggat agatatgaat ctcttgcagt tcctcggttg
    12841 attctgtcgg gtgataaatt ggcaaaatag cagcaattgg gatagctgtc tgatcgatat
    12901 caacatccaa tccaacttct ggatcaatcg attcttcgaa aatcaaataa actgcatccc
    12961 gatcttggtt tttcttaggt gctttgatac gtgcaatccc gtctcctaat ccgccaaccg
    13021 tatctttccc agttgttacc gaagtcccta tttggacaag cctttcttct gtgattagct
    13081 gacggatatt gtttctgttc gtttcagcga tttgctggac gaattcttta ggagtcatgt
    13141 tttcagcagc ttttttttca tgataataat cggtcatgtc gtaaatggca aatgtcgctc
    13201 catttagtgg caccgtctgt gaaatgatat ctgctgtttc ccctgcttcc tcagagatag
    13261 ccaagccatc attttcatgg tattcaaatt gatcgttata atcgatatct cgaatcatcc
    13321 gtttatgcaa cacgaattcc acgacatctt cccctgattc ttctgccgac atcgcatgtg
    13381 gaagaaggac tgctgcaagc ggtagtaaaa caagtaattg aagcatcaaa cacaacagct
    13441 ttttcattac cttgctccct cctttttaga ttgtctgaca aacaaaccat aggctgctcc
    13501 tgcaagcgcc atgaagaatg cagcaagcag gatatagaat aatcgtccgg atcctcctgt
    13561 agcaggcaac ggattttcag gatcgttccc gacactaagc tgtaatctga ttcgatttgt
    13621 ctccaaaagt tcatattcta actcttgctg tagatcaggc gtctctgctt cttcgtttgg
    13681 ataatacgaa atctcaactt ttagtgtacc cgcttctttt cctggaacta cccgatcatt
    13741 ttctatgtca ggttcttctc gataactaat ttctaaaata aagtaacctg gaagttttct
    13801 atagctgtca ggtgacttca cttccttgat ccgatagacc ccttccaaca agtctgaagc
    13861 attgaatagg gaagaatcgt ttggatctgg tgccaagcct ccctcgatga tttcatactc
    13921 tcctgcacta ttttgtttct caattgaaaa ttctgcgcct tcaagacgtc ggctattcat
    13981 actgtcaatt ttcaaaagtt ccaaatcgat tggcgctagt tcatcttcta aggttacttg
    14041 tagtacacca tcgatgattt catagccttc cggcaaggga gcagtttcgt cttcgatgac
    14101 cgtatcttca atgataaact taccttcttc attcagtgca aactggaaca cttgatcaga
    14161 tagccgatac ccatttggtg cgacagattc cgagacctca tattcaccaa tagacagatg
    14221 cagaggttgg tcgtaattta aatcgacata cttttctact cctacggcac gagaatagaa
    14281 gtatccgatc ccaggcaaac gtttcgattc ttctggttct aacggattac cagtgtatgc
    14341 tcgatacagc gggaaggaag aatcccccac tttcctgata tcgaaacctg caccatctaa
    14401 tgtatggcct tcatggtcta attttctaac tcggatctcc cgataatcaa acgtattgta
    14461 agcagtgaat gctacccata aacgatcctc ttcatctgtt gtatacgtga gatattgcca
    14521 attttcttca cctgtttgct tgagttggat agtccctata gcattatcgt aaagtcgcaa
    14581 gatccatgtg tcattttcat caggttcttt gaaaccttct gggttctggc tctcaatgat
    14641 tttgtattct gcatagttgg tagtttcttc actatcctta taaacaaatg aatctggctc
    14701 tccgattgga tgaataactt tctcaccatc cacgattaca tatttcccgt cttcatctac
    14761 tgaatagaac gtgagtctcc ctttctcttc ctctacttcg ttcacaccag aaagcccttt
    14821 cgctactgga tatccgattt ccagtccgtt accatctgtt tcataaagtt caaactctgc
    14881 gccattgatt ggcatattac tgccttcaat tagtttattg atattcatgt ggattggctt
    14941 gaattcattt cgcatttcca gtttgacata caactcatca tactctgtgc cttctatgtt
    15001 aggctcttgt acaacagaaa gcttgtgata ttctccttca taataggaat tcggatcttt
    15061 accttccggt ccgccgactc tcgaaccaga tgtatattca tctacaagct cgtagtgacc
    15121 taacatctca tcttcgttgg ctgcatattt tttgatttgg aattgatacg tctcatctac
    15181 taactgataa cgtggtggtc cagcgatctc tctgatccaa aatatgtcgc tgactgctcc
    15241 agtttcatct cctaaaatcg gcatcttcgt ttcaaagatc gctattccgt ccgtggtagt
    15301 tttacttgtt tcgattggtt cggcttcccc actctctgga ttttggtcat ataatgcaaa
    15361 ttcgactcca gccaacggct cgccattttg acccttcttg ctgacttgga aattacggcc
    15421 tttatgttcg taacgaatgg aagaagatgg gaaatacatc cgtccagtag tgatatcatt
    15481 ctcataatcc tccaggttct gaatataggc catattgttc actgtgcaaa aatttccgtc
    15541 ttgagctccc gcatcaagtt ttacttggta cttgatcctg accatttccc cttcacctaa
    15601 agaaatcgga gaaaatttat aagcttggtt ttcccgtccg acatacgttg tcggagtcgc
    15661 cactacttct ggtggggctt gtccatgacg ttcttcatcc catatttctg gctcttggta
    15721 cttcatgccg ttttctcctg gatctagatg gtaaaactga atatctgccg atctgccagc
    15781 tccaaatggt gagacattaa aaccagtttc atcataaagt gtggcttgct ggatcgttct
    15841 cttgaaggta gaagagatat cctccaaggc tgtaacaatg tcattcttgt tgttcgcatt
    15901 gtaatatcgc ggtgttacgc catcttcttc taaatcagca atatttttca atacatttcg
    15961 tccaatagca tctagtcgtt gtctcccgct aacgtttcca tcgattccta aaccaatgga
    16021 gaagatactt ggcgggttct cttgatactt gtttttcagc caatgatgat aagcaactgt
    16081 gttgatcgca gatgactttt cttgcgaagt aggactgcca ttcgtattgt tattagaaga
    16141 accatcacca acccagtgag tcgctttatt atctccttct tttacctctc cataacgata
    16201 gtgtacattt acttcatctt ctggacggtt aaagtcagat gcataggtaa ctggatgagt
    16261 aaaccctgca ttagaagtat tcccagaaaa ctcctcaaaa tttctgaaca aaacgtcatt
    16321 atcttcagca atcttatctt ccatcacagt ccagttgctc caagctccat tagtgctcgt
    16381 acgataactt gactgaatcg gtgcataact gaaggtcggt gtcccatctc ccacaacgat
    16441 taggattttt tctggatttc tattttctcc gccattgtct ttatacaatg tttcatagcc
    16501 atttttaagc cctagtgtaa gcggagttcc tccgattggt gtacgattta atgctgtatt
    16561 ctcacttccc gtcaaacgat tgatatcatt tgtcaatgga aagatgtccg aactgatttg
    16621 ctcatggtta ttgatagctg tactattatg gtaaaaattc accataccga ttcgaatatc
    16681 cagactcggg tcagagagca gatctttact catttcgttt actgcctcaa tcaacgcagc
    16741 atttttagtt tgactattgg tcccagcggt taattcactc atactcgctg acttatctag
    16801 aacaaaaacg atatcgattg gactgatttc ctttttctcg cccccgatga catctagata
    16861 gacattgtaa agggttgttg catcttcagg atgtagatca gatgctgtgc tgcttggcag
    16921 aacaggttct acccattttt tgatgtacgc cccgttataa tccaagtaac tgttttcaaa
    16981 attccgttca tttccccaaa gctgaacggt ttgagctgga acgtttctat cttcttcgcc
    17041 tgcagttgat ccattattag tagcatagtc gtaatttcgc cagttcgctc ccccgtttgt
    17101 ataatcacta tcatcgatca agttctctcc gtcatatggc gagcctttgt ctccttgata
    17161 gcgttcattg ctttgtgtcc aatttcctaa cacttttgta tagtcattcg ttgtaaactt
    17221 cgggtagcga tgctgttcgt tttcaacttc tccgctagga tagatatatt cataggggtc
    17281 ttgcgtagct gttggcccaa gacgctccaa aataccgttg aataactggc gttgaatgcg
    17341 ctggagtgct tgaccgctgg gtacgattgg ttcgtccagc ttttccatct cattttcttc
    17401 gctacgttga atttcagcgg aatcttctgt atcagtttca ttttcttgta attcttggtt
    17461 atctattctt tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat
    17521 cttttctgtt tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac
    17581 ataccattct tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga
    17641 ggatagacct gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat
    17701 tgctaaacgt attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc
    17761 aagggtttct tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa
    17821 tacctcatcc tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata
    17881 gactgactgg aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa
    17941 ttttaaccct ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat
    18001 caacaaaaca atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat
    18061 atccttttta gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa
    18121 attttataac gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta
    18181 cgctttcctc gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt
    18241 cgtacaatta attcagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc
    18301 tcctcctaaa atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa
    18361 acaagcaaat aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac
    18421 tgataaaaag gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt
    18481 gtaaaggaca agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat
    18541 aaaaagcaaa ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc
    18601 tctagtatca ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt
    18661 agagatatta ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt
    18721 ggcgaacttg ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct
    18781 cctttttaag aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca
    18841 agaaactgaa acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa
    18901 ggatcaacgt gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa
    18961 atgcagtaat ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga
    19021 gaagcgcgct taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc
    19081 caccccaata gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta
    19141 aactatcttg ctttccataa agagagaagt tctcacgaaa ctttttccag aatagtgaac
    19201 cgagcttttt ctcttcattt ttttgtaatg ataaatcata tacagaactg ttcgacttgc
    19261 agttcctaat gtgaaaacag gcaagacgca caggaaccat agtagctgta aatggataag
    19321 acgtggaatc cattcaatga tttctaagaa ataatcattg gcttttttac caatcgatcg
    19381 attcatcatc cttttgaacc tcctgtcaaa tccatccctt caatgaaata acgttgtgca
    19441 aaaaagaaca gcaaaatcgt cgggatcaag acaagtgttg ctcctgccat cagataattc
    19501 cattgtgtcg ttgcttggtt ctgaaaaact tgcaagccaa tctgtaacgt gtatttttct
    19561 tgatcttgga tatataacag aggacctaag aaatcattcc aagctgcgtt gaaggaattg
    19621 atcgcaatgg taatcaaggc aggtttcgtc aatggaagca tcaaatgact ccaaatatac
    19681 aaatgattcg ctccgtcgat ttcagcagct tcgatcaatt cattattgat cgataagtaa
    19741 aattgacgca tcagaaatat attgaacgca ttgccgaaga acgatggaac gatcaggggc
    19801 aaataagtac ctacccagcc gatcttggag aataatacat attgagggat catcgttaca
    19861 aaccccggga tcatcatcgt agaaagaacc aaagcaaaca tcagcttttt cccaggaaaa
    19921 tcaagcttcg caaatccata agcaataaaa gaatttgaaa ggacattacc gatcactact
    19981 agcacagtga tgaataatgt atttcttgca tagcgccaaa aaggaaaggc ggcaatcgta
    20041 tccagatagt tttcccatac gattttttct gggaaaaagg tcggaggata acgaacgatt
    20101 tcttccattg gtttcaatga agtaaacacc atccaaagca atggaatgat caaaatgatt
    20161 cctattactg tcatgaggac ataacttagt atttttttgt ttgccgattc acactggtct
    20221 ttttgaaata atccatcatt tgccgtcacc tccagaataa tagacccact taggtgcaag
    20281 cttcaaattg acaaacgtca gaaccaacac gatcagaaac aggatcattg acatagccat
    20341 cgcataaccc atatcaaaag ctacgaacgc cttgttccac atatgcagat tataaaaaag
    20401 caaagaattt gcaggtccgc ctgttccatt tttcgtcatg acataagctt cttgaaaaat
    20461 ttggaaagaa ccgatcgtag aggtgatcac atcgtaaaaa ataataggag tgattaatgg
    20521 caaagtaata cttttgaact ttccccaaac gcctgctcca tcgatttctg ctgattcata
    20581 taaagatcta ggaacatttt gtaatgtagc taagtaaagt agcattgctc ctccagaact
    20641 ccatattttc atcaaaatca acgcaggttt cgtccattgt ggatcaaaca gccaagctgg
    20701 tccagggata tggaaccagc ccagaaatgt gttgatcaat cctgcagatg gagaaagcag
    20761 ctgcatccat aagatgtaga ctgctactcc tgataagact gccggtaaat agaaagctgt
    20821 acggaataca ctgattcctt tgattttttg attgagtact gtggctaaaa acacactgaa
    20881 aatcgtcgtc agcggtacat tgaagatgac gaaataaacg gtgttgtata acgatttcca
    20941 aaataaatca tcgtgaacga acattctttt gaaatttgct agaccaatga aattcatctt
    21001 ggatgtcaaa ttataatcgg tgaaactacc aataactgaa aaaagcatag gccctagcat
    21061 aaataccaag aacccgataa taaaaggcga gataaataaa taggcccatc ttgcttcttt
    21121 tttctttcgg atagataaac gcttcaaatt ttcttgcctc ctctgtacct agacagtcaa
    21181 aaatggatta ttgattttgc ttgactaagt tttctactgc tttttgtgca tctgccaatc
    21241 cttcttttgg tgattttgtt cctaaaagaa tctggtcaat ctgttcattc actaatgtcg
    21301 tgtaatccgg agcatctaaa ggaactggtg tgatcaccgt atttttaaag ttttcgtccg
    21361 ccatttgata gatcattttt cctttatccg ttaggttgtc attattcact aaattctcat
    21421 tggctgtctt gctcgccatg atatcaaaac ttttttcgcc gaatttttct tgtacttctg
    21481 gagaagaaag atatttgatg aattcataag aggcctcagg atcttttgct ccgtatggta
    21541 cttccaagac gaatccgcca ccccacgacc aatggcctga accttcttct ttttctggga
    21601 gctgcatcac gccaaaatca aaatcatccg gtgcattttc catcaaacta gagtaataat
    21661 tgatattttg ggcacgcatg gctactaatc cggaaataaa tggatcagat acaccagacc
    21721 caaattcggc ttctaattta ttgatcgtat ttttcccata ataatcttgc cagtcttgga
    21781 tccactccaa ggcttccact ttatttttag tatcaatctt gactttttca tctttgtcaa
    21841 accaactagt cccgttatct gcgtttagcg cccatacatc agcccctaaa ttccataatg
    21901 gataaaaacc gatgcgtgta aattcttttc cttctttttt atctagttta cgtgctgttt
    21961 cttctaattc atcccaagtt gtcggtagat cttgttcact gattccagct tctttaaata
    22021 tctttttatt ataaaaaatg acttgtgtat ctgtattgaa tgggatcgca taaggatcac
    22081 cttcatattc tactgtatcc caaagctgcg gataaaaatc cttagaagtg tctttttcta
    22141 catatttgga gagattagtt gcttgctgtg cttctgctct ttgggcaacg gaatttatgt
    22201 cctgtacaat aacatcgggt gcatttccag ctgttattgc agataaagat ttagtccaga
    22261 tgtcacccca tggctgatac ttataattta catggatctc gttttgtgat tgattgaaat
    22321 cctcaatgat ttcttcgata gcttcttttc gtgcaccgga tccccaaaag gaccagaaat
    22381 caatattttt tcttccatca cttgtttttt cagaagaatt tgctgcactt gaactggcat
    22441 cgcttgcatt acttgatccg catcctccta ataaaaacaa tgctgaactt gccagcaacc
    22501 ctgtaaacaa taattttttc atattttacc tccaaatttt aatgtaaccg atgccggttt
    22561 taatataacg atatcatttt gttctgaaaa taacaattta taaggtatga ttctaaaaaa
    22621 attattaatg ataccaatac tttatataat tcgcgagcgc tttctttgaa ttttttaatc
    22681 tttcgtagca gaatgagaat gtattaaaaa tagattagga ggaattttga tgtttagaca
    22741 ccagaaagaa ttgcagtttg aagcaaaacc agatcgtccg aatccattaa tcgcgaaata
    22801 tctgcaggag ctgatcggcg gccaatatgg cgagatgagt gtagctatgc agtacctgtt
    22861 ccaaggctgg agctgccgag gagaagaaaa atataaagat atgctgatgg acattgcaac
    22921 agaagaaatc ggccacgtgg aaatgttggc gacaatggtt gctcgtttat tagagggtgc
    22981 gcctgttgaa gatcaagaag cagcgatgca aaaagatcca acaatcggtg ccattatctc
    23041 tggaatgaat ccacagcacg cgatcgtagc tggcttagga cctcgtcctg ctgacagcgt
    23101 gggcaatcca tggtgcggtg cctatatcat tgcgagtggc aacttgttag cagactttag
    23161 agctaattta aatgccgaat cacaaggaag acttcaagta gcacgtattt acgaaatgat
    23221 cgatgatcgt ggcgtaaaag atatgctgtc tgttctcctt gcaagagata gctatcatca
    23281 aaatctatgg gaatgtgcag tgaaagaatt agaagaaaaa gaaggttcaa tcttagtccc
    23341 aagtactttc ccgcgtgaca aagaacgaaa agacattgct tatgacttct ataacttctc
    23401 agagggagac caaagtagtg aaggttcttg ggctagtggc aaagcactgg atggcgaagg
    23461 cgaatatcaa tggttgaaag aacctaagat cgaaggcgct gcaccaaaat tagaaccagt
    23521 aacaccaaaa atgtatggga cacctccatt caagaaataa atatctaccc gtagaaacac
    23581 ccgttttttg ttccacacgc tttgtgagca aaactgacta aagtcattaa tcataaccac
    23641 ccttcaaaag ggtggttttc tctagagcta taagctcaaa tcaccggcca gcgcctaaag
    23701 acgctggctt tcatatttta tgttcaagcc atattgcctt tgccagtttt gcccacctct
    23761 taaaaggttt atgtactact ccttagccct taaaaggatc gtcttactct cgtacactca
    23821 gcttatctaa cgcactatca tgtttttctt gttcttgaat gtactttttg atggtcgctt
    23881 cattttgtcc tacttttgtc acatagtatc cttccaccca aaagtgtcga tacccaaatt
    23941 tatattttag atttgcacaa tctcttgatg atctcctgaa tattggctcg atattgatta
    24001 taaattattt ttcttctata ctttggtgtg aatacaatgt ggtatttaca catctacttt
    24061 gtacgggcta aactatttcc ctttattgct ccacccgcat agcaagtggt tttgtatttc
    24121 aatcgctcgg cgcgctcaat taggtctaaa gacaataaat ctaaaaaccc gctgcttcac
    24181 tgacagaaac aacgggtttt cagaaaaaaa tgaaatgaaa aagatctctt acggcaatct
    24241 attttatttt tttgattttt tataaatgga aaatgcttca agaagtccaa gaaataaagc
    24301 cgtataaaaa caagaaccta tgaaatcttt atttattaga tattcaacag aaatcccgat
    24361 aacactagcc aacaatatat ttatcagaag tgtaaaataa ggatgctttt tatagaatag
    24421 aactagtgtt gttttcatag actctccttt cttcatattt ccaattaatc acaaattcac
    24481 ggcattacta gaaaaattaa aggggcgcag aagtggaaaa atactcttcg actttcccta
    24541 caaaccaggc catcttgtgt ttaataacta taccaaatct aaggtacctc taaatctaaa
    24601 ttccatttgt ggcggtgacc tccaattttt aactcttcta tctcccatcc agtatacata
    24661 accttgatac ttcgaccact tatatatcga acacacaaat acctatccat tgcaggagta
    24721 ctacctaact tagttgctac ttgcatctaa ataacagctg aaaagatagg acttactctt
    24781 agtaaagtat ctgaactatt aatttttaaa ctatcatttt tatcctcaac tacatgcaca
    24841 tctgttgcaa cttcactttc tgtctcatcc agataaatga ttaaggaatc gggaattgca
    24901 atatcttcag ctgacgctgg aatagttgag ctaaattagt catcatatct ttattataaa
    24961 ataaccaaca gcaaaaaata caatgaaaaa caaacttgga actaatgtat cattaataaa
    25021 tgttgaaaaa ttcagcaact cattactgta tgattttagc agcccaacca acatataccc
    25081 tataaaagct aataagatgg ttaggaatcc tttagaattt ttactcattc atagacactt
    25141 ccttaaataa cttttattat agaaggtatt gtaaataata atattgacaa aaagtgactc
    25201 aaaataaaaa aaaccttaca ttatactgga atgaactgta ttgatagtgt acctaaaagc
    25261 tctactgaca taagatcgtg taatcggtaa agtaatttta ttaattatac gggatgtaat
    25321 caattagaga ataaactaat cataaaaggt acttttacat tcataattgt cgctttgaga
    25381 ttctactttg gttcactatc tgacccaatt gcacattttc gatcattaca agtattggtg
    25441 tcgttagaac aactaaataa aaactagcgg tagatttttc agaatctatg ctaatttctg
    25501 tatggatgtt ccagtgatgg caaatttctc ttttcattgt ttttcttgtc gcatgatatg
    25561 cctttttgtg ttattcagtt aaactataga aattctttcc tagacagatc ttgatcccaa
    25621 attttacgtt tttgagcatc gatatagttt aaaatgacat tactcatatc taaagagttt
    25681 agatttttta ggactaaaac tgtcagttgt tctttttctt ctttctgtta aagtattgtc
    25741 gcgacttttc gtatacgtta agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa
    25801 cgaatgactt gaggaaatca cctcaatcat tcgtttaaaa tgctatatat tctttagttt
    25861 aagatacgga aattaatgcc atcgaccaca ctagtagaat gaacgacatt tacttggcct
    25921 ttttttaatt tcgttatgtt tagcatataa aaatattata gagtttactt acaatgctta
    25981 aaacatatac tgtataatct gatcaatttt agccatgtct tgcaatggta agttttctat
    26041 ttttttgagt tttcgttcct taaaatcaag agattttaat tgtgtaataa ttacttgtcc
    26101 ttttatatct agctcttcag gtaatgagta acgtgtcggt aaattcttta tagtggaagt
    26161 aattggacat atgaccgaaa acattgtttt acggttaaat tcataacgag agacgactag
    26221 tcctggtcgt cttttttgaa tttcttttcc tacggaggga tcaaaatcaa tccatacaat
    26281 atcacctttt ttaggaatat aaattctttc ttctgacact ataaaatttc tctcccttca
    26341 ggagttaaat cttcccattc gtctttctca taatactcgg cctcttcccc accactaaat
    26401 ggatcttcaa tttttggaac taacgtaatt gttccatcat cagaatacac aacgatatat
    26461 tcttggtttt ctgaaggttt ctttccgtta tcagaaggta aagttaccac tacagaactt
    26521 ccttgtaatc tagattttgt aacaagcatt atcatcactc ccttaataaa agtatactat
    26581 ataacactaa gtaacgcaaa attccccttt gtaaactatc tagaaaattg ttttgtttaa
    26641 agtatatctt attggatata aatagaaata aattgtagcc agttcatttt ttctttaact
    26701 aaaaaaataa tccaagaaac attgaaccta tggatccaaa agctacccaa atactatagc
    26761 taaccccccg ctaccttcaa ttttgcagat aaaacgcttt gggagaaaat ttcaaagaca
    26821 acaggccatc ctatcatgcc cgattataaa caaaaagctg gctattcctt ttgctctgac
    26881 aaatttcaat tgggaaagtt cacgaaacta gcaggtgaag aagtttcaac tgttcggatc
    26941 aaagaatgcc cgcttcaaat agaaacattg gttcaacgaa tttcaactag acaagacttt
    27001 gctattgtag aacgtgagat cgtagctatt tttgtagaag aagggatttt acatgatcca
    27061 actcatatca atgtggataa atggcaacct cttatctata aattcagaga atatacaact
    27121 gccaaccagt cgttaacttt gaattttaga ttccaagaat tcaaagagtc ataatgataa
    27181 acatcgttag gtataaataa aaaagactcg cagcacgagt aaaaaacaaa tagaagctat
    27241 acattagaaa ggtcgactgt gaccctatag atgcagtata tgcagcttat gagcatttct
    27301 tctgttctct ttgtttttgg gatctgtgct gaagtctttt tcgttttttg ccgctctttc
    27361 tttgaaaaat cgattatgtt ataccttctc cattactaat tcaggcatct gctgagtaat
    27421 gatttttcgc gcaaaagaaa tatctgttac ccaaggttcg atttgttctt cagtcaagac
    27481 aagcggcatt cggtcatgga ttggtgcgac tgtgcggtta ggttcagtag tcattatgat
    27541 tgattctgcc attttttcat cctgatggct acgataaaaa ccgccaatat acactatttt
    27601 ttccttattt gaaaacataa atttgtcttt ttcttcattc cactcattgg gaaaacacaa
    27661 cgattttgca aaaatggttg atgaaaggtc tttttttctt ctactgtctc tgcacgggca
    27721 ttaatcatca attgtccttt tttaaatccg gtaaatcccc acttcatgat ttccggagtg
    27781 aggatgtttt cttcctcttt tcttaacgtc acaacaagat ttgacggaaa aacttctcca
    27841 gctgctaatt ctgctgcctg cttcggttgt ttcgtctggg cttctcgata ataattctga
    27901 aggagctctg actctagatc aaaaaaataa cgaccacaca tcctaatccc tcccaatctt
    27961 tttttctatc atacactgca acaagaagtt cgcaccaaca aaacgctttc aatttttgta
    28021 gaactaaaaa agttgtgaca agtgacaaac tctccagtga atggtattct cctgccaact
    28081 cctcggtcac aagtcacaat attcaacaaa catgagaagc tgctttttga aattgttcct
    28141 tgtgactcgg agtgaaacgg caggcttacg acctctgggt aaacggtgtt caaaagccag
    28201 tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa gctattttca caaaattttt
    28261 cttaatactc gaaactaagc gactttttca caacctcttc cttaaacggt gttcaaaagc
    28321 ttgcatctgc ggtaataagc ccaaccaaac gaaaaatatg agcagctatt tttatttggc
    28381 tgttcttatt acttgatgca gggcagcttt ttcacaacct ctccactaaa cggtgttcaa
    28441 tcagctaacc ttcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt
    28501 tgtttctcta atactcaggt caaagcgctg atttcacaac ctctaataca cggtgttcca
    28561 gaagtagctt cttcgaaaaa taagccgaaa tttcacaaaa atttgagaag caattttcgt
    28621 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctaat tattaaagaa
    28681 ccttttgcga agttaacaat ctttctttga tcaattgaaa attctgccta agtagtgata
    28741 gatcctgtgt gactttcaac aataagatac ttccctggat ttcagcaatc aacgctttgg
    28801 cttgacggtc tgcttcttca tcggacagtt tttcttcaga aagtgccagg atattttgtt
    28861 tcgtatactt gacccattga ttgactaatt ctagtagcaa cagacggtat tcttcatcca
    28921 ctgtactcaa ctcaataatc aaattaccta caggacaacc atgataagtg atctgtgtct
    28981 catgatcagc gaaaatccag tccaacattt cttctaatgc ttcttctggc tgttttccag
    29041 catttaagat gtcttcgaac aattctgtct gccatacgtc catatgcgca tggatcaccg
    29101 ctagacaaac ttcttttttt gaagaaaagt aataataaaa ttgacctttt cctgtatcag
    29161 aagctgctag aatatctcgg attgacgttt catgatagcc ttttttataa ataagatctt
    29221 tggtcgcttc caagatcttt tcctttgttt tcaatgatat tctccttttt catttctcat
    29281 agtcctatat tatacagtaa attcatcatt ttttcttctt aatcgtttaa aaaagactgt
    29341 gccaaattat ctgacacagc cctcactata aaactgttct catatagcta gatgttcatt
    29401 gattcaagaa ctgcgaggac aaaagcaatt cctatcttat gatagttgct ctaatacttc
    29461 ctctgttgtc atcacttgat ctgcaataaa gccaaagttc gtcaacgctg catccattgc
    29521 ttcttggcca ggagcaccaa ttgcatctgt cgctaccaca acattgaatc cactctctac
    29581 caattcacgc atatgggaat cgctacacaa gtttccgttc attccaccaa gaattactgt
    29641 gtcgattcca ttttttctca attggagcgc caaatcattg ctttctggtc caaagatttt
    29701 atgaggagag ctgatgatcg tattttcatc caaataaggt ttcaattctt cgataaaatc
    29761 ggctcctgaa ccttcttcca ctgattcata ttgacttttt ctagcaaaca tctgctgctc
    29821 aagcatcata tgttctcctg caccgccaaa ttgccattta tggtcatgtg ggtaaaaata
    29881 atgaggagaa ataaagagtt tgtatccttt ttcttttgct tgttttacca tttcaatcat
    29941 attttcgatc gtattgtatt tttctaagat atcttttgtc aaaccaaagc caccgcctgc
    30001 tggtttcaag aactcgactt gcgggtcagt gagaactact gctgtatttt tattattgaa
    30061 catggtggat tctccattcg ttatttattt taatacatca tttagagctt cactcattgt
    30121 cggatgagaa tagatttgat ctctcaataa cgtataagga agttttccat tcatagctag
    30181 cgaaatcaag ttgatgactt catgagaatc ttccgcatag atacttgccc ctagaatcaa
    30241 gtcagtttca gggtcgacta aaactttgaa tacaccttta ggatcttcta atacttgtgc
    30301 tttagggaca ccgcttgtca tatacttgaa taatttgtaa ttgacgcctt gtgctttggc
    30361 ttgtttttct gttaaaccta cattggataa agtcggagtg ataaatacac tgtaaggcac
    30421 agctttccgg ttattcgttg ttcgtttatt ctcgcccttc aactgatcca taatgattcg
    30481 ataatcatct agagagatat aagtgaactg caatccgcct ttgacgtctc caatcgccca
    30541 aatgttgtct gcatctgtac gaaggtattc atccacagcg attgctccgc gatctgttag
    30601 tttaacatct gtattttcta atccaagtga tgctgtactt ggttttcttc cagttgcagc
    30661 caaaactttt gacgcttgga ttgttacttc ttggccatct tctgtaaagg tgacggcagc
    30721 tgttgattct tggtctgcta cttgatctac agatacacct agatggaatt cgattcccgc
    30781 atttgtcatg tcttctaaaa tcatttgcgc gatatcttca tcttcacgtg gaagaaattc
    30841 agaatgggca tcaagaacga caactttaga tccgtattca ttgaacattg atgcaaattc
    30901 caagccaata tatccagccc cgatgatcac taatttttcc ggtaattgtt cctgatccat
    30961 cgcttgcgta gaatcaatca agtagcgact tgtattcaat cctttgattg gtaaaatgat
    31021 tggttcagaa ccagtattga tgaaaatccg ttcgccttca acaatcactt tttcaccatt
    31081 attcgtcact tcgatttgat ggttagaaag aaaacgtgct gtaccgtcca tcactgtccc
    31141 agttgcctca tcgctgatca tatgataatt tttggcgcga agcatgcccg tcaatttttc
    31201 tttccgagca acagcctctg taaagtcgat tcctctttct ccattgaaaa tcaatgattt
    31261 agaaggaata cagccgatgt tgatacatgt tccgccatac atacgtgttg acttttcaac
    31321 gactaaaacc gattcacctt ttgaagctaa cgccttcgct aaagtcttac cgccctttcc
    31381 aaaaccgatc acaatatttt gatatttttc catcattttt ccctcgcttc ttttttacct
    31441 accgattggt acaaaaatat gataaccgat aattgtctat tctccaaatc atctgcttta
    31501 tttgtcaaaa aaaaccagac aaaaagcggt cctttcacgt ttttagtctg gttcgatttc
    31561 ctttattctt ctaaacaatc gttacttcta catcgatatt tcctctagtt gctttggagt
    31621 aagggcagaa ttcatgcgca tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat
    31681 cgatatgcac ttctaatact acaccgatct gatagccgcc atcatctaaa ttataaagag
    31741 agacacgtgc ttttactgtg gactctgctg tcattcctgc ttctttgatc atatgttgta
    31801 ccgccccatt gaaacaagaa gcataacctg ctgcaaataa ttgttctgga tttgttcctt
    31861 ctgcatggat tcctggagga gtgattttca tatgcatcga gccatttggt gcctcgactt
    31921 ctccattgcg cccgccatgg ttgatcattg ctgtttcgta tgcttttttc attgtactgc
    31981 tcctttcgat tgaccatttg ctacttggct ataattatag tgtatgacaa gtaaggcgct
    32041 ttctacaaaa attctgctta ttcgaatacc agaatgccgt cttctactat ttttccaaaa
    32101 aacaaaaaaa tactactcgt gaacaacagc gtcatatttg ttccaaaata aatagcaatc
    32161 ttttctacat aatcttttat atgattgatt ttaagataca tatataccag aaagttgacc
    32221 ccataaacca atactgttaa aaaaataacc atattcgtta ccattttttc ctccttttgc
    32281 tggtctccct accagcactc gatttaacca taccactttt tttgccgtcc aagcaactag
    32341 cctttcaaaa agactggttt attctgctgt taatgattca agatcagaaa aatgtccgaa
    32401 taattttgct aattttacta acgccaactt gttctttccg aattcatcat tttctatctg
    32461 taatactagt aacggctcat gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg
    32521 ctcttctaga tcatatcgaa taccttcttc attttccggg tcgaagttca tccctttttc
    32581 ttcttccaac agtcgcttca tttcttctaa tatcttgttt ccttgttcgc gtggttcatc
    32641 gctgaacaat tttaatcgga tttcttgtac ttctacgggc tgtttcaact ctttgatttg
    32701 ttcatctaat gtgatacctt ttctttttaa ttctggcaaa agcatcagga tctttgcgat
    32761 gacatatgca ccatcatcca gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc
    32821 gatggctagc tgtgtatctt tcccaagacg gttaagttct aatgctttat tgattacatt
    32881 tcgatagccg gaaatataac gaacttggat gcctcctttt tcttcaatga atctttgtag
    32941 atgagaagaa gtaggggaat tcgtcacgat tcttgttcct ggatgctctt ttaatacgat
    33001 tgtacttaat actgcgatca aattatttcg attgatcact gttccagaag cactgacaac
    33061 tgcagaacga tccacatctg tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac
    33121 agcctgcttg atactttcca tcgcttcttt attatcagga tttgggatat gattaggaaa
    33181 tcggccatct ggttccaaaa attgggaacc tgttgaatcc gcacctaagc tattcaatac
    33241 tttttcagca aagaatccac cagcaccatt tccggcatca acaatgattt tccaaccatt
    33301 tagtggtttg ctttctagtg ttccaatccc ctttttaatt tttgtgacta aatcttgcgc
    33361 ataaggtgtc aaaaggtctg ctttttctac gcttccagtt tgttcgcttt ttattttttg
    33421 ctgctgtgat aggataaaag caatatcttc tttttctgct cctccttctg aggtaaagaa
    33481 ttttattcca ttataataat agggaagatg gctagcagtc agcataaccg cagcatcgca
    33541 cgagaactgt tcaaattgag tggacataaa catagcaggc gtagtagcta attcgaaatc
    33601 gatgacatgt atcccttgtt ctttcagact ttggatcaac gcctctttca gtgctggtcc
    33661 gcttatccta ctgtcatgac caatcccaat cgtccatttt ttatttggat cggttgattt
    33721 cttctttttc tttatccagt ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt
    33781 caagtttact tcatatcctt caactggtaa tgcgattcct cgaatatccg atccattttg
    33841 cagcgctttc atatctttca tataaaagtc ctcctcattt attccctcat tttttccagc
    33901 ttttctgcaa atcgctgtgc ttcttcttct gagcggcaaa taataatgaa tgtatctaca
    33961 ccggccatcg ttccgacaac ttcagggtaa gccacttcat ctagccaatt cgttaccaca
    34021 tcggcaccat ttcgttcagt caatacgata accatgaact gaacagactg gatacgcaaa
    34081 acctcgcgtc taattgctgt acgcaaacgt tcttcattta aagaaacaga tggctggtta
    34141 aataatgtat agcgtactat tttgttttca ttttgacttt ttactaactt catttctcga
    34201 atgtctcgag aaatcgttgc ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc
    34261 agctcttcct gtgtcccaat aggttgttct gtaatgatct ggcggatcag tgcttgtcgc
    34321 tgtttctttt tcatattaga cacctctcaa tgttgattat agcaaaagat aagtaatatt
    34381 tcttcatatt ttggtatttt ttacttttat tttttgtttt cattcaggtt gctaaccttt
    34441 ttctatttta acacgcaaaa tcgtcttcat tttttcaggt gctgattttc ttggatcgct
    34501 gatgtaaatc tctttgtgtt ctttagaagc tctttcatag ccttcttttg cgatgaatgc
    34561 ttctaatttc tcaaacgttg ctggttcttc ggcatagggc ccgacgtgta agatttgggc
    34621 acaaagacct tcttccatct ttttgaatac tacttgttct ttcaagtctt ccggaagttt
    34681 gctagaacgc tgaatggctt cttgtgctat cgcttctgta acaaagtcag gctgtcggat
    34741 catcaattga taagaaaaat gttctttttt catcactggt tcatgcaaat acttttcttg
    34801 cagtccccat tgtccttcca gtggatagac agtatacatc tgataatcag gaatcagcca
    34861 atttttttta ggcgacatgc gtattgcata gctgactgca tatagacagg ctactcttcg
    34921 tttaaagtct tcctgattcg ggtcgccgat ccctctgatg ctaaagaatg attttttagg
    34981 aacctctagt atttgcgggc tttttttcat actatagctc ttgtctttac gccattcaat
    35041 tttttccatt tttcttcctc cgcgaaattc catttagtta tttattatca tacctctttt
    35101 tgagtgactt ggctaatcgt gttgacacta tttttcagtt tgtgctagaa taagtgaagt
    35161 aaataaatcg tacagataac acgtttcggc gtgtcgagag agaggcggtt tctattttta
    35221 taatagaaat cactctcttt ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca
    35281 aaaacagctg cttttagtac ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt
    35341 attgatcgag acggccatga atgtaacttt cccaactctt atcagacagt ttgatttaac
    35401 gactgcacaa gtccaatggg taacaacgat ttatcttttg atgatttcga tcattgttcc
    35461 gctgtctact tatttgaatc gcaattttag tctcaaaaaa ctctttttag cttcaaatct
    35521 gcttttcttg gcaggtataa tgatcgattt cttctctcct accttcatgg tcctattgtt
    35581 tggtcgattg ctccaaggtg cagcgacagg tatcgctctt ccgttgatgt tccatattat
    35641 cttgacattt gcccccctca atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac
    35701 ggccattgct ccagcaattg gccccactta tggaggcatt atgacttcac attttacatg
    35761 gaatcatatc ttcctgtttc ttgtgcccgt tttgtttctt tctttgatta tcggctggtt
    35821 tgctattccc gagatggcag tacaaaaaag tggttatttg gattggataa gcgttttagg
    35881 aatttgtctt ttgtttagtg gaagtctaac atttttgagt acgttgggaa cagtttccag
    35941 ctggattgct ttaatcatcg gcggtattgg ctggttcctt ttttactatc gaagtaaaaa
    36001 agtggagcat ccactgatcc gactgtctat tctttcaaat aaaacattcc gcttgttttt
    36061 gattggcttc ttagtttatc agtttttatt acttggtgta tcttttgtct tgccgaattt
    36121 ccttcagatc gttcaaggaa gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc
    36181 agcggttggt gctttgcttt ctcctttttc cgggaaaatg ctggatcaat atggtccgaa
    36241 gaagccaatt tttgctgggc tgattctttc tttgattggt tggctagcat tattcctact
    36301 cataggacac gcttcagtgg gtgtattgat tgcttgtcat gtgttttata tgatcggtat
    36361 cggattatct tacagcaata tgatgaccac cggaatgaat gcactgaatg aagaactaca
    36421 aggagacggg aacgcaatgt tcaatacctt gcagcagttt tctggcgctg tggctacttc
    36481 attagtagcg gtcattatca attacgtcca gcatcatact tcccataact atgaagtgtc
    36541 tactacatta ggatcaaaag cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt
    36601 tgctcgattc gcctattatc tgttctttgc taaaaaagcg tagattccat atacggcagg
    36661 tgttgcatct gccgtttttt tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg
    36721 gaaaaaattg ccattatcgg tggcgggatc attggtatga ccctagccag ttacttagat
    36781 acatcaaaat tcaatgttgc tttatttgat gaagggacag gacaggcaac taaagctagc
    36841 gctgggatta tctccccttg gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct
    36901 aaagacggcg ctgctttttt ccctaaactt ataaaagatt tccaacttga tcaaacgatt
    36961 tacgcacaat cagggacact tttgcttcga cctgaaaaag atttagctga attggctgtt
    37021 cttgccgaga aacgaaaaga agaagcgcca gaaattggaa acatcgaatg gctttcacct
    37081 gaacagacat ctcaagcact tccgttattg aaaccagcag tttcactgcg tatcagtggt
    37141 ggtggtcgtc tggatggaaa agcatattta gaacatcttg gtcagcgttt agcacaaaaa
    37201 caaatggagc agatccaggc aaaagtcact ttgcataaga agagcgattc ttggctcatc
    37261 aagggaccgt ttggagaata cacagctgat cgtgtaattt tgacacctgg cccggcactt
    37321 aagcctttat tacaagaatt aggctatgct gcagatatac gtccgcaaaa agggcagctc
    37381 ttagcatttc agacatctta taagatgagt caagactggc ctgttgctat gcttgacgga
    37441 gaagctgatt tcattccttt catggatgga aagatccttt taggtgctac ccatgaaaac
    37501 gatcaaggct gggatttggc tcctactagc gaagcttata agggattgac taagagtaca
    37561 gaacagttct tgactgatcc agatcagata aaaaactggc catacgagtt ccgtgtaggt
    37621 acccgtgctt atacgtcaga tttttcccca tttttcggcg tactgccaga tgatccaagc
    37681 ttactggctg ctagcggtct aggctcttct ggcttgacca caggtcctta tatcggctat
    37741 ctattagcca acttcttaaa tactggtcat tggcctacgg aagattatca aaaggacatc
    37801 tccacctata ttacgaaaaa tccatcatag aaaaacagct ttttcaagta aggatcccga
    37861 gcgatattgc gcatggatta cttcttgaaa aagctgttat tttagttcaa tttctgaatc
    37921 aaattctcca aactttcttt tgcttcatct ggcaagagat cttttcctat ctgagcttca
    37981 atgaatcgta aacgaatatc aagtcgttgt ttcaccagat ttttatagga cgtatcctca
    38041 aaagaaacag gaaaatctgg tataggtaaa tagtggatgt cttcaaatgg accaaacgac
    38101 ttgaattctg ccgtttgttg cacgattctt tcaacgattg acaatgtcgt ttcaggtttg
    38161 atttttttat catcgaaata tccagtattc aggacatagc aggctgtttg ctgtttcaaa
    38221 aacaactctc gaaaagcttg atagtcttcc ctaagaggat agacacggaa aggattagca
    38281 aatggttcaa tgactagctc atctagctgt ctttttgtag tgatattttc cgcgtctgat
    38341 cgttttgttg ctaatgttgc accaaaagac gctgctaaaa ctgggtcatt gatcttgata
    38401 attggcggaa gcgaatcatc tttcatgatc caaaaaacag catcgatctt ttcgctaaga
    38461 tgatcgactc ggtcgggtgt cgcataacgt gatttgactg tccgcccatt tccgtttcgt
    38521 atatctcctg ttactaggac tttttctcct ttacttgtac atgtcacgcc cacattctga
    38581 caagtaagga aagaagaaat ggccggatca tcagacggat agtcttgtgt tttatcaaag
    38641 taagaaggtt ccaaggcagt agcaaaacca ttttttcgag aaataacgaa agcatcgtca
    38701 tgcaagatcg aaacagagtg accttccgta tgttttgcta aggtaatcgt tgattttcca
    38761 gaaccggaca acccaaatac agccatcgta taggtctggt cattactagc atattgtttc
    38821 atcccaccgt ggcaggcaat aaagccattg cgatttccca atgcccaagc aagcgtcaaa
    38881 gtcgcttttt ttaattctcc aaagtaacgt aatcctagca cagccgctgt attatggaga
    38941 gcatcaaaca aaatgagtcc atttggaaat gtttcatgtg tccattcggg atcacaaaag
    39001 atataaagat ctccctcatc aaaggaaaca gacttttgat aagtctctaa gatcttcgaa
    39061 ttcgctggct gaaaattcag caaataagaa tacaaattgt tctcaaatcc ttctggaatc
    39121 agcaaatgac tttgcacaga aaattcttca gataggccaa cgattacttt tgtatggtaa
    39181 aactggcgct tgcgactttg atacacagct tctcttaaaa ttttctcgta tttgctttgt
    39241 tccttgtcta agtcctcaaa gatccgccga gcacttgctg ttcttcccac aatgcttcca
    39301 tcattgaata ctagtgtcct aacatcagct ggtaaatcta gttcttcagc atgtgagatt
    39361 gttaaatctg tgatgatcgt tcctggactc ccttttgcta gttgataagc tgtcttccta
    39421 tcaaaaactt catgaacatt attaccgtaa aatgtcgttt ctacaatcga tcgaatactg
    39481 gataacagtg gatttccact tgtgatttcg tttaattcga gactctcttt tgtactcatg
    39541 gctcctcctc attccctaaa caaaaaaacg ttttctttat tatacattat tcgagttttt
    39601 atttgtactg ctgcgctgtg ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa
    39661 cttgaataaa caagtttctc ggtttcatca ttttcctttt atcggcttag taccagccgt
    39721 ttgctaacca gaatgtttta gcagcatccc atgaaccata acgagatgtt acatattgtt
    39781 ctgctacacg ttcttgattg gcagctgaat agtcgccgtt taagtatgaa gcatctaatt
    39841 gataacggcc gatgtaacgt ccgttagtag ctgtgtatga accgcctgat tctttttgtg
    39901 cgatccattc ttttgcagag cttgaagttg gcgctgttgc agcagctggg gcagcaggag
    39961 ctacttcaac tgtttcaaca ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg
    40021 tagatgctgt attttctgtt gttttgtttt ctgttgttgc tgaagaatca tttgaagttg
    40081 ggattgttaa ttgttcacca acataaatgc ggttgatgtt tgcgatcgaa tttttttcag
    40141 caattgcatc gatcattgag ttgtctcctg caaatttttg tgagatctta gataatgaat
    40201 cacctgattt tactgtataa acttcatcag cgtgagcatt tgtagttcct acaaacattg
    40261 cagtagcacc agcagcaaaa gttgtaccta aaacaatttt cttaaatgaa ttcatattaa
    40321 actccttttt ttctccgttt tttattcttt cgacgctatt aactttatca tttagaaata
    40381 tttcataggt aaaagaaaca tgacatttaa tgacaaaata acgaattatt taatatttgt
    40441 aacatttaaa caaatatttt tttgatacaa aaccataaaa gccttgttgt ataagcaaag
    40501 taatcgtttt tctatgtttt tttatttttg aatgaaaaac gcagattctg taacattcac
    40561 tgcaataatc cataaaaaaa agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa
    40621 aatgtaaaaa atacaaaaaa accagtaatt gttacaacaa ttactggaca aaaactttga
    40681 ataatgttaa ctattttttt attttaactt tctccgcaat aatttctggg catgttccaa
    40741 ttcgtttata acgacttctt ctgtttcttt agctaatatt tcatctaata catcaagcca
    40801 tttttccggt tcttttgttc ctagacgtcc aatagcccaa gctgctgttc ctctgatgac
    40861 agggcggaca tctgttaaac attctgaaat ctcaggcaat gccgttcgat cacctagatt
    40921 agctaaagca atcaatgcgt ttctctgcaa aggtttcttc ccacgccatg aaccagctaa
    40981 atgcccaaat tgctgtttga agtctttatt agacatcgaa agcattggct ttaattttgg
    41041 atatatttcg tctacttttg gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt
    41101 gtaagggcag actaactggc agatatcaca tccataaatg acatttcgca tttttttacg
    41161 atattcttcc ggcatcatcc cttttgtctg agtttgataa gacaaacatc gctgggcatt
    41221 cattcttccg tcaccaagca atgcttttgt cggacaagca gtcacgcagc gcatacagtc
    41281 accgcaacca aattctcctg gtttatcagg ctcaaataca atattagtaa cgatctcacc
    41341 aagatagaca aatgaaccga actcttcagt gatcaacaat ccgtttcgtc caataaatcc
    41401 taaaccagct cgctgtgcta cagcgacatc gatcagttct ccagtatcta cttgcggagc
    41461 tagacgccat tcctcttctt tttgccattt ttctgctctt gtttggatga attcgatcaa
    41521 tcggttcaaa cggtctctga gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa
    41581 ctgcccgcgt ttttcatccc taggcacttc ttcatggatc ctagtaggat acgcaagtgc
    41641 aatggaaatg atcgatttcg gctgatcaaa tgtcatttct ggataaagac gctcatcgat
    41701 atttggatgt tcaaagccag aagtatggcc agctgctttt tgttcttcca acgattcttt
    41761 taatgaatca aaaggttccg ccgtggtgaa cccgattttg tcaattccta atcgtttgct
    41821 ttcttgtatg atttcttctt ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta
    41881 taacccataa tatagttttt cttttttcag ctggacaaac tggatctgct gatcggcaat
    41941 cttcttttct tccatccatt tttttcttgc agcaaatact tcccaataat ttgttgaaat
    42001 taattttctt ttgttatcta atgcattaaa aaaattcaat gaaactggtt ttgtacttaa
    42061 cagttcatgg agccttacct cttcccatgg cgaaaactca gacagatcgc gggaatacaa
    42121 tacttcttca tagagatttt tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg
    42181 cctagcaatt tctactagac gattataaaa catattcatt aatttgctgt tggcaataaa
    42241 ttgactttta taataggccg actggatctt tttgattact ccttctgctt tgatgactga
    42301 aaataatgca ggccatgctt tgacggttat ttcgtcgttt tgtttaacta atacgccagg
    42361 tgtgaagccg actggagaaa ggaacacaaa ataaccgata ccggtatttt catctaaagg
    42421 ctgaaattca tcaaacaacc atttgcctat gtacagctct tcatctggtt ctgttgtctc
    42481 attttgattt gctatgaata atttagctaa ttctgcttca agaaattgaa ggtcttgatc
    42541 cttgtcggta ttttcctgct ggctgatcaa tcgaaagact tcttctttaa tcgtatattt
    42601 atctttacgt gtaaaattca tagccacacc ttccttcctt actctaacta taacggaatt
    42661 tcttcaaaaa aggtatctgt acgacgaaaa acagcataat tttttttcat atctcttata
    42721 aaaaatgcaa ggtctgctcc tcaagctaga ccttgcactt ttcagctttc ttttgtttgt
    42781 gacaaacctt catggatcgt ttcaatattc catttcatca tctgatagta agaatctcct
    42841 tgttctcctt cttttgctat ggaatcagtg aacagtttat catagatttt caaacccgtt
    42901 tcttttgcta cccgttccat gcttcttgag tctacactgg tttccacgaa taaaaccggt
    42961 acttcttttg ctcttatctg atcaatgatc gctttcattt gatcaggcgt accttgactt
    43021 tctgtattga tctcccatat ataagctgct ggcaaatcat atgctcgtga aaaatacttg
    43081 aatgcccctt cacttgttac taataatttt ttgttctctt cgatagaagc aaaactttcc
    43141 ttcgcttgtg tatctaattc ttttagtttt tccacatatg cttctgcatt ttttttatag
    43201 agtgtcgcat tttctgcatc tttttcagag aatatacgtg cgatttcctc cacatatttt
    43261 attccgttag ataggtctag ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta
    43321 gttaaataaa gaggttctac atttttgcta actgcaaaat aatcttttcc ttcttctttt
    43381 ttagccgttt ccatcaagtt atcgaaccag ctgttacctg tttcaagatt caaaccgttg
    43441 tataaaataa catctgcatc gcttgccttt ttgatgtctt ctggtagtac ttcatattca
    43501 tgcggatctg ttccgactgg tacgatactg tggatatcta tttgatctgt tccgacctct
    43561 tttgccatgt ccgccaagat cgaattggta gccacgactg acaacttttc tttacttcct
    43621 tcatccgctt ggtcagaagc ctgctttccg caaccggcta ataccaagaa actaactgcc
    43681 aagattaaaa agagtgattt ttttgttttc atctatctgc ttcctttctg aaataaaatt
    43741 ccttttgttg gagaaaataa aaaagcaagg ataaaaaatg cggtacatgc taacacgatc
    43801 gtagctcctg atggccaatt gtaactataa ctgaaaaaca caccgacaac tgcacttagc
    43861 ataccgattc ctgcagctgt aatgatcatt ttcagtaaat ggttcgttag caagtaagcc
    43921 gtggcggctg gtgtgatcaa catggcaatc accaagattg ttcctactgt ctgtaaactg
    43981 actacagcca ctaatgtcaa aaagaacatc aaaagataat ggatcagcga tgtgttcagc
    44041 ccataagctt ttgccattgt cggatcgaat gatgtgatct tcaattcttt ataaaagaaa
    44101 aagacaaata tcaagacgat tccactaacg agtgctgtca gcaacaaatc gctttcccta
    44161 acagctaaga cattcccaaa taaaatatga tacaaatctg tcgcactctg ggcatatgaa
    44221 atcaagataa tccctaatgc aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt
    44281 ttcaatcggc tccgctgagt cacgaaacca atcactgctg ctgttagcat cccaaaagca
    44341 gtggctccaa agatgtaact aaaaccaaac atataagaaa tggctacacc tggaagaact
    44401 gcgtgagaga tagcgtctcc catcaaagac atccctcgta aaataataaa agaaccgatg
    44461 actccagaag caagtcctac aagcatggaa gtgaccaaag cgtattgcag gaattgataa
    44521 ttcattaatc catcaataaa ggattggatc attttttctc tcctcctttt actaaatgtc
    44581 tgatgatctc accataggcc aattgaaggt tcttcgatgt aaagacttct tgtactggac
    44641 cggaagcgat cagctgttta tttaaaagaa taacctcatc gaaatattct tctactttat
    44701 gaagatcatg atggacgatc aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt
    44761 caaagatctt tcgttcactt aacgcatcaa tccctacgaa tggttcatct aaaaagatcc
    44821 attctgctcc ttgggctaga gctcttgcaa taaaaactct ctgaagctgt ccacccgata
    44881 gttcgctgat ctgtcttttg gcatattctt ccatccctac ttttttcaaa gcttgtcttg
    44941 cacgttcttt ttcttttttc ccaggtcttt gtccaattcg taaagatgga tatgttccta
    45001 aaagtacaac gcctaataca tcaattggaa aggaaagatc caattcactt cgctgttcca
    45061 cgtaggctat ttttttacgg actgagttta ccgactgtcc agaaaaggtg actttaccag
    45121 tagtagctgg tatcaactct agcaaagatt tcataaatgt tgattttcct gcaccgtttg
    45181 gtccgataat accggtaatt ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag
    45241 ttttcccttg ataagcggct gaaaggtctt gaattacaat ggccgtacgt tccaaatctt
    45301 acactccttt ttaggtttac ctaacttttt atttaaatat agtttaacta aaatggaaag
    45361 cattttcaag tagaatgatg aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat
    45421 tttctgtaga atcacatcaa gagttcaata aggctaacct aataatgaaa aacatgtgtt
    45481 gaaacgtttg attatttttt cttgttgact caacaacgaa aggagttttt gtatggaaga
    45541 agaaaagtta actcgaagtc ttagtgcccg tcatatccaa atgatcgcac taggtggaac
    45601 gatcggtgtc ggtctgttta tgggtgcctc ctcaaccata cgttggacag ggccctcagt
    45661 gatgggagcc tatgcgattg caggattctt tttgtatttg attatgcgtg ctttaggcga
    45721 aatgctttac gttgatcctt cgactggttc ttttgcaaat tacgcgagcg agtacatcca
    45781 tcctgtggct ggctacttga ccgcttggag taatattttt caatatattg tcgtaggaat
    45841 aagtgaagtg attgctgtag gatcttatat gaattattgg tggcctgatt tgccggcaat
    45901 tattcccgga atcattgtcg tcttgtttct tatgctggca aatcttattt ctgtcaaggc
    45961 gtttggcgaa ttagaatttt ggttttcgat catcaaagtc ataacgatca ttttgatgat
    46021 cattgcaggt cttggggtaa tcttatttgg atttggtaat catggtcagg cagtagggat
    46081 ttcaaatctt tggaaaaatg gtggattctt cactggaggc gtcaaaggat ttttctttgc
    46141 attatcgatc gttgttgctt cctatcaagg aatcgaactg atcggaatga ctgctggtga
    46201 agcagagaat cctaaaaaga cgatcattga agctgtccag tccactatcg gtcgaatctt
    46261 gattttttat attggtgcta tttttatcat tgtgagtatc tatccgtgga atcaattgag
    46321 tgagattggt tcaccttttg tacaaacttt ttctaaagtc ggcattacat ttgctgcagg
    46381 actgattaat tttgtcgtga ttacagcggc attatcaggt tgcaattcag ggattttcag
    46441 cgcaagtcgt atggtctata cacttgccat aaatggaaag atgtctaaaa aatttctgaa
    46501 actatctcgt cacggtgcgc ctttttatcc tgtcgtagca atctcaggtg gaatcttaat
    46561 tggtctgatc ttaaattatc ttctaccaat gttcatcaac cagtcagaaa atattttcgt
    46621 tttcgtatac agctcaagta ttttgcctgg tatggttcct tgggtagtga ttttgatcag
    46681 cgagattcgc ttcaaaaaga agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc
    46741 actatctcct tatacgaatt atgtgacact tgctttttta gctatcgtat tgattttcat
    46801 gtttatcaat cctgaaacga gaatctcatt gattattgga ctcgttttct tgctttacat
    46861 gacgatccat tactttgtac gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc
    46921 accttagtgg aagcttcgtt cttttttatt gcttttatca attcaatttt agcgtctcac
    46981 cgggagtcag gaaataattc tccatgctca tcccattcag cgacaagatc gtttctactg
    47041 gtacgccagt tcgttcggct atttgatttg gaccttctcc ttccaaaact acggttgtcg
    47101 cagcctgtga agtcgcgctg ttggtattag tttcagagga atctgttgtg tcttgtgttg
    47161 ttcgagcttg catttcagaa gcttctaccg actctgctgt ctcagaatca gaagatgttg
    47221 tgtcttgtgt gcttgttgac tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg
    47281 aaatcttagc gacatgattc gtataattag ccgataattg attgatcaaa gtatctaagt
    47341 ctacaccgtc tttattttct gctgcctgat acgctgcacg taattttctg atcccttcgt
    47401 cggagattgc ttgaagctca cgtgcttttt ggttagcaac tgctgataaa ccagctattc
    47461 cctcttgatt tccctgaatt tctgtctggt attcttcaat caatgcaggc gtcttttctt
    47521 cgatcttttt cgaataatca tttacgattg cttgaagttg ctctggcaaa ccatttgctg
    47581 ttttttcttc agaagtttgt gtctcttttg ttttagttga tgactcactt gtttgtttcg
    47641 tctctgtttt ctttgtcgtt gtttccgtta tggtcgtact tttcgcttct gacgaatttt
    47701 ttccatgaaa atatagaccc gcaactcctc ctgctatgat caaaaacacg gcaactgctg
    47761 ccccaatcat gatcatccgc ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc
    47821 gaacattttc tccccactca ttttcatcat acattttttt caccaccaat ttttatgtat
    47881 aatagcgtta tcaaacgctt catattctta ttgtagcaaa taattgtcgc tgtgcacatt
    47941 tttatctttg ttatttataa gaaaatttca ccagttgaga tgattccaag attgtccgtc
    48001 gatttctcct tgcagctgca ttgttcgttc gtctatctca gccatcagtt tctttatttc
    48061 atataagagc gcacggtctt gatattctga tttttcgctt aattcatcta attgttggat
    48121 cagccaatca tttgtcataa tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct
    48181 tcgatctgct cttttgcctc agtcagtgct tctacgatat atgcttgttt ttcagattct
    48241 tcttcctgca ttttctgatt ttcctgtact ctttgaataa accagtcaat ccgctgagtc
    48301 agcgatggtt tgccttccaa tgagagatac tgctgataag caattagctt ctcccaacgt
    48361 ttttcctggg ataaatacat aaattgtgct aaaacgaatg gcggaagata ggtcatatgg
    48421 aatttatttg cgattcgctg atacggcctc aaaaattcgg aaatcgtata ttcttctttt
    48481 cctccagctt ggtattcttt ttccgccaca cctgttgtca atacgattcc tagttctttc
    48541 ccttttaata catgtgctgc tcgttccaag acattatctt gccaaatttt taaatgagca
    48601 ggagaactat accagtaaaa cggaaactgg aaaatgatcc gatcatgctg ggccaagagc
    48661 tgtagttcag tctctatatc tatttttccg tctggataac ttgattccaa atgatgccaa
    48721 gtagctggta aaccagcaga agcttctttg aaaaattgct gatttaaaga ttcttcgatc
    48781 gttggatggc taatgatgat aagtgtacgc atcccttttc ctccttttta gtcttcgctt
    48841 tacagtgtag cataaccgcc acaagtttct tttgccgatg cttgtcattt taaccagact
    48901 aatcaggttg tccaagaaac tgcggtttgt ttttccaact gttttttcaa ggtatccaaa
    48961 gcaatattct taaaattttc gtttttcata cgtttacgat agttcgtagc cgtttctccg
    49021 gtactctttt tgaacattcg gctaaatacg actagactat tgaaccctac ttgataggca
    49081 atactttcca cggattcatc cgtcagagaa agaagaaacg cccctcgatt gatccgtacc
    49141 ccgatcaaat attccttgat actggtaccc atatgatttt tgaatactcg cgacaaatgg
    49201 ctccgattga ccgctaaatg ctgggcgatt tcctcaacag acaatttttc agcataatgt
    49261 gcctcgatgt atttgactgt ttcaacagct aaagaggaat gaaccttttg tacaccaccg
    49321 ctgacctttc cgccatcttt taaaaggact gataaaaaac ggtaggttaa tgctgttaac
    49381 tgtaattcat tttccaaggt ttcttccgta tctttcatgc attctaaaat aatgtcgata
    49441 tatttttgta tgtcagaaga gaccatcgtg tattggtctt ctctgaaaag cgactgccga
    49501 atgatttctt ctgcagcact cccaccaaat gaaagccagc aatacatcca cggatcttct
    49561 ccatctgata agtaaaacgt cgagtctcct ggacgaatca agaacagatc accttttttc
    49621 aattggaatt gttgattttt cacatgataa gatcctttgc cttccatcac gacatgcagg
    49681 atgtaatcat tgcgaatagc aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca
    49741 caaaaatcaa aatacaattc tttttctact tgttgatgtt ccttttttaa aaaaatcgat
    49801 tgctccacgt ctatccctcc ttactccttt agtataatgc aacaaaaagt taaataaaag
    49861 tcacagaaat atattaaaaa ggaagcgatt tcttgttaag tttaagtcat taaaagatct
    49921 ttgttattcg ttgtaaccgg tttacttagt attatatatt gaacaggaga ggaatacaga
    49981 ttatgaaaag caaaatgatc caacgtgtgt cctacgcttt aggcgctttt ggacacgaca
    50041 cattctatgt tacattaagc acttatttta tggtattcgt gacaagccag atgttcgcag
    50101 gaacagataa ggcaacgaat gcaaaaatga ttgctacagt tacaagctta gttgtaggta
    50161 tccgcttagt tgaaattatt tttgatcctt tgattggtgg catcatcgat aatactcgta
    50221 caaaatacgg taaattcaaa ccatggttag ttatcggcgg cgttgttagt tccgtactct
    50281 tggtagcaat ctttaccaat ttctttggct tagctactca taatacgact ttatttatca
    50341 tattatttgc aatcgttttc atcttattgg atagttttta ttcatttaag gatatcgctt
    50401 tttggtcaat gattccagct ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt
    50461 ttgctcgttt cggctcttct ctaggtgcaa atggtactac tctagtcgtt gtccctatcg
    50521 ttactttctt tacctatctt gttactcata aacatattga aggcgcttca ggctggttct
    50581 ggttcggtgt gattgctgct gttatttcag gcggtactgc gattatcact gccttgggca
    50641 caaaagaagt cgatactgcg atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt
    50701 tcaaagcagt tgctcaaaat gatcagttga tgtggcttgc ccttgcttat atcgcttatg
    50761 cgattgccaa tgcagcaaca actgccgtat tattctactt cttcaaatat gtacttggcc
    50821 aaccaactga attttggatc gttggtctag ttgctgcctt acttggttta gtagctgttc
    50881 cactattccc aatgcttaca cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg
    50941 caatgatgat ttcttcttac tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta
    51001 tcatcgggct agtattgttc tacttccctc aacaattgat tttcttatcc gctttgatga
    51061 cgatcacaga ctctgttgaa tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta
    51121 ctctatcaat tcgcccttta ctagataaaa tcgctggtgc tttgtctaac gggatcgtag
    51181 ggtttgtcgc tatcgcttct gggatgactg gtaatgctac tgctgctgat atcactgctc
    51241 atggcgtaac gactttcaaa gcttatgcat tctatgctcc tgctgctttg atgattttct
    51301 ccgctattat ttttgcttgg aagattacat tgacagagaa aaaacatgca caaatcgttg
    51361 agaaattgga aaacaaattg gctccagctg atacaatgga agatgaactt cacgatgcag
    51421 tagatccttc ccattaagaa aggatcttga aaatgaagat tacagaaaaa gattttggcc
    51481 aaggttatca cttgataacc ttggagaaca aaaacaagct agcactttct atctctgatt
    51541 taggtgctag aatcgtcagt ttaaaatcaa atgatcgaga attagttttg ggatttgaca
    51601 ccgctgaaga atatatcgaa aaagatccgt atatcggtgc ttctatcggt cgcaccgcag
    51661 ggagaatcga aaatggccgc ttttctctca atggaaaaac ttaccaatta gccacagatc
    51721 caaaaactgg acataatctg catggtggtg ctcctggatt tgaattaaaa aaatggtctt
    51781 atgtcatttt gaatggcgaa aatgaagctt ctgtcatttt tactactaca agtcccgacg
    51841 gagaacatgg ttttccaggt acaatggatg tggaaatccg ctatactttg acaaaagata
    51901 atatctggcg agtgacctct cgcggcacca gtgaccaaga tactttattc aatccgacaa
    51961 atcatgttta cttcaacttg acgggagatg cttctcagtc aatcgatcaa catgagcttt
    52021 ggctcaatag cgaagcttat gctcctttgc gaacagatag tattcctata ggggtaaaag
    52081 aaaatgctgc aggaagtgct ttcgattttc aaatacctaa aaaattagcg tccgtttttg
    52141 ctagtgattt ggatcaaaaa aatcttgttg acggaatcga tcatccattt ttcttaaaag
    52201 aaaccggctt gggtaaagaa gccgctcgct tgactagccc cgataaaaga atccaagtag
    52261 atattgctac agatgcttct agtgtggtta ttttcactgc aaatttcggc acagaaacac
    52321 cagaaatgcg caaccgaaaa ctggcacatc acggtggcat cacatttgag actcaaacag
    52381 ctccaggtgc agagcgcttc tcagcatttg gttcgattca tttaaaagcc ggatcagtat
    52441 ttgaaacagt aacagaattc aaaatcaaaa caagaaagga ataactcatc atggaaatca
    52501 aaagaagctt aaacacaaaa tttgccgaaa cattcggacc taaaaaaact acacaatact
    52561 tctcaccagg acgcatcaat ttgattggtg aacacacaga ttacaatgga ggccatgtct
    52621 tccccgcttc catcacttat ggaacgcaag gtgtagcagc acctcgagac gataataaaa
    52681 tattagttta ttccacaaac tttgacgata tcggtgtcat tagttttact ttagatgagc
    52741 tagaatatga taaaaaagca aactgggcaa attacgtaaa aggaatggtc cttaaattaa
    52801 aagaagctgg acactcaatc gatcatgggt ttgagttatt agtggaagga acaatcccta
    52861 atggtgcagg actttccagt agcgcttcat tagaattatt agtaggtgtt gtattagaag
    52921 atctgtttga tttaaaaaca gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa
    52981 atgaattcat cggtgtcaat tcaggtatca tggatcagtt tgccatcggc ttcggtgagc
    53041 tagatcatgc aatcttatta gatacaaata cgctgaaata cgaaatggtt ccagtgaaac
    53101 tagatggtta tgcaatcgtc atcatgaata cgaataagcg gcgggaattg gcagattcaa
    53161 aatacaatga acgccgtagc gaatgcgaag aagccttggc acgtttgcaa aaaactttgc
    53221 ctatctcttc tttaggagac ttagatgaag aagaatttga atcaactatt gaccaaatcg
    53281 gcgatgatac attgatacgc agagctcgcc atgccgtttc tgaaaatcag cggactttga
    53341 aggcaaaagc tgaattagaa gctgggaact tagaagcatt tggtcaactg ttaaatgatt
    53401 ctcaccactc tcttcgctat gattatgaag taactgggat cgaattagat acactagtag
    53461 atgctgctca aaaacaagaa ggtgtcttag gtgcacgaat gacaggagct ggatttggtg
    53521 gctgtgcgat tgctcttgtc aaagaagaaa atatacctgc cttcaaaaac aatgtctatg
    53581 atgaatacat gaaagttgtc ggctatgctc cggaatttta tgttgcacac attggaaatg
    53641 ggacaacaaa gatcgatcca gaagctgttc atgtttgata aaaaaatcaa cgatctcagc
    53701 taaaaacaaa tagataaaaa taacctctca gcaatttcca aatgtgagcc ttttgctcgt
    53761 atttgaaaat tgctgttttt tattgacacg gaaagagaac gtgtgttcta attgtgttga
    53821 agaggtgatt gttatgtggg cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc
    53881 aagagatatt ttatgtattg actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa
    53941 ggatcttgat ccccttacaa ctaaattagt agtcatgtcc tatccgtccg attcgacaga
    54001 aacacggggt agcggattaa tcttggcttc cagtcctgca gcaaaaaaag cttacggcat
    54061 caccaatatc agccgtgcca gagatcttcc cttcccctat ccaagtgatt tatatattgt
    54121 tgccccaagg atggcctatt atatggaaaa gaacagagaa atcaattcta tctataaaaa
    54181 atatgcagac gaagcgaacc atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac
    54241 aaatagcatg gcactctttg gtaaaacaaa tgcgtacgac atggctaaac tgatccataa
    54301 agatgtgttt gagcagaccg gaatctacac gactatagga attggcgata acccgctact
    54361 tgctaaacta gccttagaca atggctcaaa agacggaaag caaatgtttg ctgaatggcg
    54421 ttatgaagat gtaccagaaa agttatggaa aatctcagat atcactgact tttggggaat
    54481 cggcaaacga acagcaaaac gtctgaaaca aatgggtata cattctgttt atgatttagc
    54541 tcacgcggat tattatcact tgaaaagcaa gctaggggtc atcggtactc agctttatgc
    54601 ccatgcttgg ggcatcgatc gaagtttttt gggacaagaa tatacaccaa aatcaaaaag
    54661 tatcggaaat agtcaaatcc tagatagaga ttatacaaga cgagaagaaa tcgagatcgt
    54721 tatcaaagaa atggccgacc aagtcggcac tcgcttgaga cgatctgcag caaaaacaca
    54781 agtagtcagc ttatgggtag gatactcttt aggctatctt gatccaaatg gcaagaccgg
    54841 gtttcaccag caaatgaaaa tcgaagcgac aaatgctagc agagatctag cagatgcttt
    54901 attgaccatt ttccaccagc attaccacta ccaggatatt cggcgtgtag gcgtgaactg
    54961 ttccgacctc gtatacgcga caggtttaca gcttaacctt tttgaagatc ctgaaaagca
    55021 gataaatgaa gcgaaagttg attttgttgt cgatacgatt agaaaaaaat acggctttca
    55081 atcaatcatc catgcgcata gtctcttgca aggaggacgc gccatcgcac gtagttctct
    55141 cgttggcggg catgcaggtg gtatgagtgg attagaaggt ggaaaagatg agacggacag
    55201 caaaaaaatt cattgactat aacgagtatc gagatcggcc atttggatta aaatggggga
    55261 ctgcttttgc gatggaagaa ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa
    55321 acagcctctt cctaaacaac aaatgacatt gcaagaaatc gatagtatac tgacagaagc
    55381 ctttttatct cgtaaagcag taatcattca gctcaattta aaagatgaat ttggaagact
    55441 cttggatgag gtcgaagggc acttcattgg tgaagcctat gaagattact ttatgattga
    55501 ccatcagccg atattgtggg aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg
    55561 gtttgtgaca tgagaggttg tgacagaagt gatcaacttc aaaaaataag aaaggatttt
    55621 tcgaaaattg cttcttaaat ttttgtggaa ttttggctta tttttcgaag aagcaacttc
    55681 tggaacaacg tatattagat atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa
    55741 gccaaggcgc tgatttcaca acctctgtct atctatccat ctattcggta agattcatgc
    55801 atgacgtctt ctttatttag tatgtagagc cctttttctt ctgaccattc aacataaatc
    55861 agctgtttta catctgcata gccttctttc ttcaagttct ccataagcca tgcttcagtc
    55921 aattgattgg actgaagcac tttatgctga atttgccctt catctacaag caggatcgat
    55981 aaagctttgt cttcatctga ttttttcaat acactcattt gaccggcatt ctctaggata
    56041 acatgtttgg cattttcaag aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc
    56101 tccatctcga tatggttatt tgtcaactct gtcatgttga tgacgccgtc tttgattaga
    56161 acagatggct cgcctttgac ccaacgattg accttttcat ttttttggac gatacgttcg
    56221 ataccataaa tcattactgc ccaaagcgca atggcaaata ggacatgccc tacatggaca
    56281 ttgtcatcat aggttgattc ttctaagatc ccacctaaaa caagcgtata gactaaatca
    56341 aacggtgtga tttctgacat ggatttcttc ccaagcaaac gtaccactaa taataaaccg
    56401 atcaacccga acaccagttt cattgtaatt gaaaaaatca ttttttctcc ccctaactat
    56461 ctgttaatta aattatatat gctttctcac gaacacgcat ggaatataca aggaagaaat
    56521 gtatcctttt actaaaaaaa ggactgtgac actgtagtga cccccaaaag ttagactttt
    56581 ttggagtgga gaaatccact cctttttttt atgctctaaa atgatatttt tacacaaccg
    56641 ttacggttgt tttacgaaat tggacg
//
LOCUS       DASHXG010000012        50312 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.012, whole genome shotgun sequence.
ACCESSION   DASHXG010000012 DASHXG010000000
VERSION     DASHXG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.012"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(716..3865)
                     /locus_tag="U2R59_000887"
     CDS             complement(716..3865)
                     /locus_tag="U2R59_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEM8965298.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3879..5123)
                     /locus_tag="U2R59_000888"
     CDS             complement(3879..5123)
                     /locus_tag="U2R59_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEM8965299.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5116..6708)
                     /locus_tag="U2R59_000889"
     CDS             complement(5116..6708)
                     /locus_tag="U2R59_000889"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEM8965300.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7218..7943)
                     /locus_tag="U2R59_000890"
     CDS             complement(7218..7943)
                     /locus_tag="U2R59_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965301.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8097..8423)
                     /locus_tag="U2R59_000891"
     CDS             complement(8097..8423)
                     /locus_tag="U2R59_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965302.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8460..8825)
                     /locus_tag="U2R59_000892"
     CDS             complement(8460..8825)
                     /locus_tag="U2R59_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEM8965303.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8862..9077)
                     /locus_tag="U2R59_000893"
     CDS             complement(8862..9077)
                     /locus_tag="U2R59_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965304.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9206..9541
                     /locus_tag="U2R59_000894"
     CDS             9206..9541
                     /locus_tag="U2R59_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965305.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9617..11614)
                     /locus_tag="U2R59_000895"
     CDS             complement(9617..11614)
                     /locus_tag="U2R59_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965306.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11712..11987)
                     /locus_tag="U2R59_000896"
     CDS             complement(11712..11987)
                     /locus_tag="U2R59_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965307.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12219..12953
                     /locus_tag="U2R59_000897"
     CDS             12219..12953
                     /locus_tag="U2R59_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965308.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12992..14134
                     /locus_tag="U2R59_000898"
     CDS             12992..14134
                     /locus_tag="U2R59_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8965309.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="U2R59_000899"
     CDS             complement(14229..15620)
                     /gene="sufB"
                     /locus_tag="U2R59_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEM8965310.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKCEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15625..16095)
                     /locus_tag="U2R59_000900"
     CDS             complement(15625..16095)
                     /locus_tag="U2R59_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEM8965311.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16082..17317)
                     /locus_tag="U2R59_000901"
     CDS             complement(16082..17317)
                     /locus_tag="U2R59_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8965312.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="U2R59_000902"
     CDS             complement(17314..18600)
                     /gene="sufD"
                     /locus_tag="U2R59_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEM8965313.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="U2R59_000903"
     CDS             complement(18613..19386)
                     /gene="sufC"
                     /locus_tag="U2R59_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEM8965314.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19583..20431)
                     /locus_tag="U2R59_000904"
     CDS             complement(19583..20431)
                     /locus_tag="U2R59_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEM8965315.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20455..21141)
                     /locus_tag="U2R59_000905"
     CDS             complement(20455..21141)
                     /locus_tag="U2R59_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965316.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21134..22168)
                     /locus_tag="U2R59_000906"
     CDS             complement(21134..22168)
                     /locus_tag="U2R59_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965317.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(22231..22487)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(22563..22901)
                     /locus_tag="U2R59_000907"
     CDS             complement(22563..22901)
                     /locus_tag="U2R59_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEM8965318.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22903..23259)
                     /locus_tag="U2R59_000908"
     CDS             complement(22903..23259)
                     /locus_tag="U2R59_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEM8965319.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23265..24452)
                     /locus_tag="U2R59_000909"
     CDS             complement(23265..24452)
                     /locus_tag="U2R59_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8965320.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24643..25488)
                     /locus_tag="U2R59_000910"
     CDS             complement(24643..25488)
                     /locus_tag="U2R59_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8965321.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25722..26687
                     /locus_tag="U2R59_000911"
     CDS             25722..26687
                     /locus_tag="U2R59_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEM8965322.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            27064..28107
                     /locus_tag="U2R59_000912"
     CDS             27064..28107
                     /locus_tag="U2R59_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HEM8965323.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(28169..28633)
                     /locus_tag="U2R59_000913"
     CDS             complement(28169..28633)
                     /locus_tag="U2R59_000913"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEM8965324.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            28879..29826
                     /locus_tag="U2R59_000914"
     CDS             28879..29826
                     /locus_tag="U2R59_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8965325.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(30037..32109)
                     /locus_tag="U2R59_000915"
     CDS             complement(30037..32109)
                     /locus_tag="U2R59_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8965326.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(32042..32419)
                     /locus_tag="U2R59_000916"
     CDS             complement(32042..32419)
                     /locus_tag="U2R59_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEM8965327.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(32548..33126)
                     /locus_tag="U2R59_000917"
     CDS             complement(32548..33126)
                     /locus_tag="U2R59_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965328.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            33258..34550
                     /locus_tag="U2R59_000918"
     CDS             33258..34550
                     /locus_tag="U2R59_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8965329.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34610..35728)
                     /locus_tag="U2R59_000919"
     CDS             complement(34610..35728)
                     /locus_tag="U2R59_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEM8965330.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35742..37163)
                     /gene="arcD"
                     /locus_tag="U2R59_000920"
     CDS             complement(35742..37163)
                     /gene="arcD"
                     /locus_tag="U2R59_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HEM8965331.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLITDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(37409..38530)
                     /gene="mnmA"
                     /locus_tag="U2R59_000921"
     CDS             complement(37409..38530)
                     /gene="mnmA"
                     /locus_tag="U2R59_000921"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEM8965332.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38934..39533
                     /locus_tag="U2R59_000922"
     CDS             38934..39533
                     /locus_tag="U2R59_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEM8965333.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39671..40957)
                     /gene="efmA"
                     /locus_tag="U2R59_000923"
     CDS             complement(39671..40957)
                     /gene="efmA"
                     /locus_tag="U2R59_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HEM8965334.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(41228..41572)
                     /locus_tag="U2R59_000924"
     CDS             complement(41228..41572)
                     /locus_tag="U2R59_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEM8965335.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41709..42854)
                     /locus_tag="U2R59_000925"
     CDS             complement(41709..42854)
                     /locus_tag="U2R59_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8965336.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(43034..44008)
                     /locus_tag="U2R59_000926"
     CDS             complement(43034..44008)
                     /locus_tag="U2R59_000926"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEM8965337.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(44088..44963)
                     /locus_tag="U2R59_000927"
     CDS             complement(44088..44963)
                     /locus_tag="U2R59_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HEM8965338.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            45093..47000
                     /locus_tag="U2R59_000928"
     CDS             45093..47000
                     /locus_tag="U2R59_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HEM8965339.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(47541..>50312)
                     /locus_tag="U2R59_000929"
     CDS             complement(47541..>50312)
                     /locus_tag="U2R59_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HEM8965340.1"
                     /translation="VRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGS
                     KYTMRLGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGH
                     GNLFPATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYA
                     GFAAARNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFR
                     ANADGLLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPE
                     EYVEMTSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQ
                     TIVMAPGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSH
                     YWGLRGFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHN
                     LVKNCTSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIG
                     KVIIKNSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSG
                     TDIIVNSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQ
                     IYHSLNYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQ
                     IKPGNRQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQ
                     EANGVAENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSN
                     HTAIFSAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPE
                     RENPGNESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVV
                     VYVMKQRKK"
BASE COUNT        14312 a        10484 c         8832 g        16684 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccctccct aaacaaacat cttttgtaag
     3901 aagccttttt tcgtttcctt cagcaaatct aacttacgtt gatgaagagc gatcgtgtcg
     3961 tcgagttgtt tgaagaaagc gccgattttt tgttgttcct ctttattcct agtaaaagga
     4021 aacttgatat tagcgaaatt ctcatagaat aagtattctc gtacgcttcc ttcagtgttg
     4081 cgcttgacct ctttgataaa tgttggtgac ttgataaact gaagtatgaa ctcattatct
     4141 aagtcctcgc tcattttcac aactacataa agagagctaa caatgaccgt cataccaaga
     4201 ttgttaaatg caattgatcc tacgtttact cttgctggat tataggcgaa ttcatttggt
     4261 tcaacgaatt tataatttgt tttttctaaa tcatccaacc tactaccatc aaactgttct
     4321 gtttgagaaa ttaaacctgc tttattactt accgaatagg cagggaagtc taaatctttc
     4381 gtgttctttt ttccagtctt cttactaaac tctttgaact tacgctgttc ccaatcttcc
     4441 gtaaatccag gaaaccgaat ttctggcact tttgctccgt ttttagggaa cattttttgt
     4501 aagaatcctt ttttcgtttc ctttaataaa tctagcttac gttgttgaag agcgatagtg
     4561 tcgtccagtt gtttgaagaa gttcccaatt ttcttttgtt cttctaatat tggaaattgt
     4621 actatccatt ttttcacttc tgacattggt acgagatttg taattgctga acctggatta
     4681 gctcctgtga gttttctttg cataaaatct gcacgaataa attgaataaa atattctgaa
     4741 tctgtgattt ctttatttat tctaagtcta atcaaagcct gattgaatac acccggtttt
     4801 atttgctttg gtactcttga aattctccca attgttccag cgccactcat gataaaatcg
     4861 cctggttcta atttaaattt gattaattca ttatattttt tttcagtaat tttatatctt
     4921 gtttcgtaat tatcataaat agcattttgt tgttcataga caacaaaatt gctattagat
     4981 acaaagaatt ctttctttaa ggcactccca aatggtcccc tccttactcc atctttttta
     5041 tcaagtaagc attcaaactt acgctgttcc caagcttccg taaatcctgg gaaacgaatt
     5101 tctggttgta tatcattact catgtttgaa cacctccagc gcaccttgta accacgcttc
     5161 attttcaggt gttgtttgca gggaagagat agcttctaaa agttcttttt ctagcacttg
     5221 ctgttcttgt cgtatcttct tgatgtcatt tccgacatga accatatcaa ttggttcttc
     5281 ttcttcaaac gtatctacat agcgtggaat atttaagtta tagtcatttt ctttgatttc
     5341 atcaaagttt gccaaatgag cgtatttctc gacatctttt ctttcagcat aggtttcgag
     5401 gattttttga atgttttctt ccgataattt attctgattt tttcctttga caaattctcg
     5461 actagcgtca atgaataata cgtctcgagt ttggcggttc tttttcaata caatcaccgt
     5521 cgttggaatc gatgtcccga agaacaagtt cgcaggcata ccgatcacag cataaatact
     5581 gccgtcttct agtaattttt gacgaatgac cccttctgca gcgccacgga ataaaactcc
     5641 gtgtggcaag acgatggcca tagtccctgt ttccttcaaa tgatagaaac catgaagaag
     5701 aaacgcaaaa tctgctttgg attttggcgc taattttcca taacgattaa accgagaatc
     5761 gtctaagaag gtcgtatctg ctgaccaatt agccgaataa ggtgggttca ttactactgc
     5821 atcaaatgtg taaggttcat ctgttggcca atccttattc aacgtatccc cattgcggag
     5881 attcatttct tcggcatcta ccccatgtaa aatcaagttc atttttgcta gattgtatgt
     5941 cgttgtattt aattcttgcc catgatattt aacgttatct gggtgagtta agtagttacg
     6001 cacatttaac atcaatgaac ctgaacccat ggttggatca aaaacactaa agaatcgtcg
     6061 ttctttttga tccaacgtca cgatttgtgc catcatatca gaaaccatat gaggcgtgta
     6121 aaattctccg gctttcttcc ctgcttctga agcaaattga ctgatcagaa attcataagc
     6181 atccccgatc acgtccccat cgtgacctaa aacttccacg tcattcaatt tcttaatgac
     6241 ttcggtaatc gtcacatttc gttgttgctc atctgttcct agtttttttg attggagatc
     6301 cacatcatca aataacccat taaattgatt gtaggtagat gccaattgca caaaggcttt
     6361 gtttagatca ttcaattgga acgttgcttg ttttgcttga tccgctaaga cgttgaaaag
     6421 atactctggc gaaatcgcat accccaaaat atcaacgatt gttgcaatca gatcttcttt
     6481 tgattcttca tctgaaagta attcgcgata caacatcgtt tgtttgctta ccgtatcata
     6541 ttcctctaag gattcatctg ctaaaagaac cacttgttcc aacaaacggt cggataaata
     6601 tttatagaaa atcagtccca ataaataatt tttatattct gacgcatcca ttttgctacg
     6661 gagattatct gccgcactaa ataatttttg atttaattct gcacccaaaa agatacactc
     6721 ctatctctta tttaaagttg ctatataccc tcttatttta gcatactccc ttttagaaaa
     6781 agcaaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa ggagtctaac
     6841 gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta catagttatc
     6901 tttagaacca tttcagatac atatgaaaca attacatatg attttttcat aaaaaaacag
     6961 tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta aaatcactac
     7021 ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc gtttcatttc
     7081 agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca gtagcttatc
     7141 ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt aaataaatga
     7201 aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta atcagttacc
     7261 tgtccgttct taaataccac agaataatct tttttcccat tttcaagtaa ccgaagtgga
     7321 atatctttac caactttctc tgtcactgca ttactgatac ctgttagatt agctaataaa
     7381 tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt gattccttta
     7441 tcttcattta caagtttcca agtaggtggt atagctgtgt atgtttctac aaatgaatta
     7501 agtttttcat taagtgactt ctcttttata tttccatcta aaaactctgt atatatggct
     7561 tgagctatac taaaacaaag ctggccttgt tctaataatt ttacatcatt agttagtaaa
     7621 gctgtgttca cgttatcaat cgcttcaaga agagtatctt tggtgtccct aacagcttta
     7681 ggtgtgcctt ctggaatttc cctacttgat acctcgtcca ttttatcttc cataaacccc
     7741 ttaaaatcat atctttctcc caaatccata gaagtttttg agaaagcttt catttctgag
     7801 tctatttctt caataatatt taacatgtct gatacatatt gtttaggctg attcgttttt
     7861 aatctatatg tggtaaatat ctcaattcct ccaattatca ataaaattgc caaacaaatc
     7921 cataataatt ttttcttttt catttttcct cctatacact gctgttataa cagtgactaa
     7981 tgtaaagatt ttcccagcaa tcatcagact attatttaca gggaatcaaa aaaactcctt
     8041 agtaagctta cacctttagg agttcctgtt tgaacggtat gcataataca tttaaatcaa
     8101 tttaacatta acacctcagt atatggtatc tctacatata cacggtcttt ttttggatag
     8161 tactcgacat ttatattgat agcacttcca ttgtctaacg tagctttagc ccggtacgtg
     8221 ttatcaccat tatcatgagt gatcgtcaca tcatcacatg tccgatttaa gttatactgt
     8281 tcttgtaaaa tctgagttac caatggtaca gatgacttct ctagtccaga tgaacccgtc
     8341 attcttgaaa aaattatacc tataatagcc aatacaacga tacctataat gacaaacttc
     8401 ttattcatat ttactttatt caacttttta tctcctatct ccaaaatgat tttctctcat
     8461 cagtaactca ttgacatccc caatagtaca ccaaagatgg ctccagctac ccctgctatc
     8521 atcaaaatcg tacccatttg ttcatctttc tctcgatata agtaacccat aataacagca
     8581 acagcaccaa ataccacagg aataaatgct aatgatacta ccatagaaat ccaaccaata
     8641 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     8701 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtaat
     8761 gctccgcaaa actggcaata cttactttca tttgttattt ctttaccaca ttttctacaa
     8821 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gctaactgtt tactttatta
     8881 aatacatcag aaaacagctc atttattggt acacttaata tctcagaaag cattttcatt
     8941 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     9001 ttcatttttt tggctaactc agtttgggaa agtccttttt cttttctgta tcggctgaga
     9061 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     9121 ttcaactcat aaaatatata aatacttcaa atgtcattac aaatacaaca acttgttgta
     9181 ctctactgag aaggggggtg tattaatgaa acagaagcaa tatgcaaagg tcattagaga
     9241 aaagcgaaaa gcactcgggt ggacacaaaa agaattagct aaaaaaatct tctctacaca
     9301 acaggcagta gcaagatggg aaaattctgt aacagaacct aacctcgata gcttaacagc
     9361 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg acatagatta
     9421 tgaggaagag tttttggctc tctatcgctc tcttagtact gaagatgcaa ttcgaacaat
     9481 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     9541 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     9601 gctatggata acctgtctag tttaatataa ttgggtctct tctattcctt actctccgtc
     9661 catcatctct tgttacactt gtaaattgat aaataggaac taattcaact cctgataata
     9721 tcaattcttt tattacttca tctatccctg cccctttcgc tagatatact aaaaaactac
     9781 tgcttgcttt cacattgtat agtttcttaa tatccttaga agctcgttca agagtgaatc
     9841 cttgtttaac aaagtagcct ctgttttcta ttaaagcatt tttcacgctg ttatccctga
     9901 catttcgtag gcgttcacaa acagtgttaa taagttcttt ttctgtcatt agatatgtcc
     9961 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    10021 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    10081 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    10141 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    10201 agacattgct tctcttatgt ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    10261 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    10321 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaag
    10381 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    10441 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    10501 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    10561 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    10621 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    10681 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    10741 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    10801 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    10861 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    10921 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    10981 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    11041 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    11101 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    11161 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    11221 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    11281 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    11341 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    11401 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    11461 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    11521 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tctttatcta
    11581 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    11641 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    11701 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    11761 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    11821 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    11881 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    11941 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    12001 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    12061 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    12121 cataatacct cgataaaaaa ggggtgtcaa tagttttgta aaatttattt acaacacccc
    12181 ttttttgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    12241 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    12301 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaga
    12361 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    12421 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    12481 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    12541 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    12601 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    12661 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    12721 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    12781 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    12841 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    12901 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    12961 tactccttgt aaactaagag gagatgattt catggcaaaa atatcaaagt acaaaaagaa
    13021 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    13081 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    13141 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    13201 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    13261 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    13321 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    13381 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    13441 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    13501 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    13561 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    13621 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    13681 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    13741 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    13801 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    13861 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    13921 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    13981 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    14041 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    14101 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    14161 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    14221 taacaggttt acccaacact gccttccatc tcataactga tcaatcgatt gagttcgact
    14281 gcatattcca ttggaagttc tttggtgaat ggttcaacaa agcccatgac gatcatttca
    14341 gttgcttcag attcggtcag gcctcggctc atcagatagt agagttgttc ttctgagatt
    14401 tttgagactt tggcttcgtg ttctaaagag acttggctgt tgtggatctc attgaatggg
    14461 atcgtatcgg atttcgacca ttcgtccatg atgatcgtgt cacattcgat atgagagatc
    14521 gaacccgcac tgtttttggc aaaggttact tgtcctcgat agtttacttc tccgccgtct
    14581 tttgaaattg atttagagac gatagagcta gatgtatttg gtgcattgtg gatcattttt
    14641 gcacccgtat cttggatttg gtttgctcct gcaaaggcga tggagagcat ggtgcctcgt
    14701 gcaccttttc catctaagta aacacttggg tatttcatcg ttgtttttgc acctaggttt
    14761 ccgtcgatcc attcaacggt tgcgccttcg tatgcttttg ctcgtttggt tactaagttg
    14821 tacacattgt ctgaccagtt ttggatcgtt gtgtaacggc aatacgcatc ttttcttgta
    14881 aagatttcta cgatggcggc atgcaggctg ttacttgaat aagtaggtgc cgtacaacct
    14941 tcgacatagt ggatgcttgc tccttcgtca acaatgatca gcgtacgttc gaattgcccc
    15001 gtgttttccg cattgatccg gaagtacgtt tgtaatggaa catcgacttt gacgcctttt
    15061 ggcacgtaaa taaaggtccc acctgaccat acggctgaat tcagcgctgc taatttgttg
    15121 tcggttggcg gtacaagttt tgaaaagtac tctttgaata attcagggta ttctttcaaa
    15181 gcagagtcag tgtcagtaaa gacgattcct aacttttcga attcatcttt catattatgg
    15241 tacacgactt ctgattcata ttgtgcggaa gcaccggcta gataagctcg ttcagcttct
    15301 ggtataccaa tcttttcaaa tgtatctttg attttttctg gtacgtcttc ccagtcacga
    15361 gcgggtttgt cacttggttt ttggtaatat ttgatggcat cgaaatcgat gtctgaaagg
    15421 tcggggcccc atgtttgcat tggcattttg ttaaatgttt ctagagattt cagacggaat
    15481 tcaagcatcc attctggttc gcatttgatt cttgacatct cacggatcac ttcttctgtc
    15541 aagccttctc ctgtactgaa aaccggttcg acatcatcgt gaaacccgaa tttatattct
    15601 tctaattctg gtacgcccat gttctcactc ctcttccttg tggtaatgat ggaaagctgc
    15661 ggtaccatcg ttttccattg cttttcctag tgctttccag gcaagtgtcg cacatttgat
    15721 ccgagcggga aatttagcta caccaccaag catagcagca tcgcctaatt ggtcgggatc
    15781 tttgacttct tttccttgga caagctgtag aaagtctaca gttaaatgtt ctgcttcttc
    15841 tattgatttt ccgatgacgg cgtctgtcat catcgaggca cttgccgtac tgatggagca
    15901 gccactgccg tcaaaggcga tatttttgat gattccgtct tttacatcga cttgcaattc
    15961 gatcacatct ccacatgtgg ggttgttcaa ttcgatcttg cttgtcgagt cagtcaagct
    16021 tccacgatga tgcggatggg aagaatgatc caagatcact tgacggtata aattgtctaa
    16081 tttagatagt cccatgttgg aaaaactcct ttgttgccat gattgcttca actaaacggt
    16141 cggcgtcttg cgttgtgttg tagaaataaa agctcgcgcg agcagtcgct gatacttcaa
    16201 ggtacttcaa tagcggttgc gcacaatgat gacctgctct gacggctacc ccttccatgt
    16261 ctaaagctgt cgcgacatca tggggatgta acccatccaa attgaatgca acgactcctg
    16321 tccgaaaatt cgggtcttgt ggaccataaa cagtcaatcc atcaattgct tgtaattttg
    16381 gcaacacata agcggctagt tcttcttcat atcgatggat attgtccata ccgagttttt
    16441 gcaaataatc gattgcatgg cctaatgcga tagcgccggc gatatttggt gtccctgctt
    16501 cgaatttcca aggtagttct ttccatgtac tgtcgtataa ttcgacaaaa tcgatcattt
    16561 cgccaccaaa ttcaacaggt tccatttctt ctaaccattt tcgtttacca tataaaacac
    16621 caatacctgt tggtccgcac attttgtgtc cgctgaaagc aaagaaatca cagtctagtg
    16681 cttggacatc aatggccatg tgcggggcag attgagcacc atctactacg atgaccccgc
    16741 cgttttcatg gacaagttca gctaattctt gaacaggatt gaagacacct aagacattgg
    16801 atacatgagc aatggagacg attttggttt tgtccgtaat ctttttcgct gcatcctcca
    16861 tatccaggaa gccttcttct gttagttcga tatatttcaa gacagcacct gttcgttttg
    16921 ccaactgctg ccacgggata acattagaat gatgttccat gtaagagagc actatctcgt
    16981 ctcctgcttt gatatagcgg tcgccgaagg ttctggctac ccaattcaag cttgtcgtcg
    17041 taccacgagt aaacagcact tctgctgttt cttttgcatg gatgaacgcc cgtacttttt
    17101 ctcttgcttg ttcataatca tgggtcgcgc gttctgctaa cgtatggaca ccgcgatgaa
    17161 cattggcgtt atcgtgttcg taatagtacg ctaatgcctg gagtacttgt tttggctttt
    17221 gggtcgtcgc tgcattatcc agataaacta aaggttcatc attgacgtct tgaaataaga
    17281 taggaaaatc attgcgtagc tttttagcat cgatcatcca ttcaacttcc cttcgattac
    17341 ttcgactaat tctttccgaa cttgttctac agggattgct gttaagacag aaccgaggaa
    17401 tcctcgaatc actaagcgct ctgcttcttc tttatgcaat cctctactca tcagatagta
    17461 catttcttct ggatcaactc gtcctacact ggcagcatgt ccagcagtta cttcgttttc
    17521 atcgatcaaa agaataggat tcgcatcacc acgtgcttta tcagaaagca tcaagacacg
    17581 actttcttgt tgggcatctg caccttttgc ccctttcaag atgtggccga taccattaaa
    17641 ggtcaatgtt cctttttctc ggatcactcc gtgttgcaaa atatgcccga tcgtatgagg
    17701 ggctttattg gttactcgtg tatcgattcc ttggatttgt ctgcccgagc tgattgccac
    17761 gattttgact tctgcgtgtg caccttctcc tgctaaatct gagtcaaagt cagcgatcac
    17821 atgaccgtca ttcatgacac caattgccca gtcgacagaa gcatctcgta aaatgtgccc
    17881 acggcgattc atataagaag taatattttc tcctaattga tctacggctg aatatttgat
    17941 ttttgaacca gctttagcga tgacttccac gatgatatta cctgatgatt ttgctacttg
    18001 ttctttggtt gtctggaaac gttccagata agaaaattca ctatgttcat ctgccacgat
    18061 caacacatgc ttgaagaagt gctcatcgga tgcgccatct tgaatgaata aggactcgag
    18121 tggttcatcg atcacgacat ttttaggcac atacaggaaa ataccgctgt tcataaaagc
    18181 tacatggagt gcagtcaatt ggtcttcgtt catgtttact gcttttttca tataatattc
    18241 ttggactagt tctggatatt cgatcattgc agtgaacaag tcggtaaaaa tgactccttt
    18301 ttctgctaat tccacaggca gttgttcaaa aatcgtccat gaaccttgtt ggacaagcac
    18361 aggattgtct ttcattgcat caaatgccgg aatcgtgcct gtttcactga tggtttgtgt
    18421 ttctttcaca tcaaataacg accagcgatg gaatttcacc cgatcgatat gcggcaatgg
    18481 cagttcatct gctttcgcta gtgcgtcttg acggaaggtt ctcatccaat caggttcgcc
    18541 tttacttaaa gaaaaatcat ttaccgcgtc aagataatcg agccagtttt tttctttcat
    18601 tcttgctccc ccttacgctt cttcttcttt atagtcgatt cctaattctt tactgatacc
    18661 agcgtagcct tctgcttcca gacgtttagc taggtcagca ttccctgtca tgactactcg
    18721 gccttccatc atgatgtgaa cgacatcagg tgtgatatag ttcaataatc gttgatagtg
    18781 ggtgatgatc aatgcaccga aattgtctcc gcgcatttca tttactcctt tagcaacgac
    18841 tttcaaagca tcgatatcca gacctgaatc gatttcgtct aaaattgcaa atgtaggttc
    18901 taacatcaac aattgcagga tctcattccg tttcttttct ccgccagaaa aaccttcgtt
    18961 cagataacgt tcagccattt cttctggcat atttagtaaa gccatttttt catctaactt
    19021 tttcaaaaat gccataacag aaattttgtc gttttcatca cgtttcgcat tgatcgctgc
    19081 acgcatgaat tccgcattcg tgatacctgg tatctcactt ggatattgca tagctaaaaa
    19141 taagccaagt cgcgcacgtt catctacttc caagtctaaa acatttttcc cgtcaaacaa
    19201 aatttcgcct tctgttactt catagtttgg attgcccatg atagcggcag ataaggtaga
    19261 ttttcctgtg ccgttaggtc ccatgatggc atggatttct ccggttttca ttgttaggtt
    19321 tacgccttta aggatttctt tttcctcgat cgacacatgt agatttttta tttctaagac
    19381 agacatgcat tataccccca aattctcttt cgttctcact cattttagac taattgagaa
    19441 tgaagcgcaa tgaccttcct tactaaaatc aaatatcttt tatttattat taaacaattt
    19501 tgatttctaa attagaatag gtataaaaaa gatgagaaat aagccattac agacttattt
    19561 ctcatctttt ttgttccata ccttattttg catcagcctt tactggttta acagagccgc
    19621 cccatttgtc tgtgatccat tcttggactt ctttgcggtg aagcacttca atcagttttt
    19681 tgattttgtc actgtcttca tcacctttac gagtcgcaat aatattcacg taaggagagt
    19741 tgtccttttc aagcaatacg gcatcttcta atggattcaa ccctgcgccg taagcgaagt
    19801 ttgcgttgat tgcaactagg tcaccttcat cattttggta cgtagaagct aaaagtgatg
    19861 ggtcgatcgt atggttgaac ttcaagttct tagggttttc ttcaatatca tcgaatgttg
    19921 ctgtttccag atctactcca tctttgactt tgactaagcc agcatcttgt agaattgtga
    19981 tgatgcgtcc ccagtctgat tcagaatttg aagtaatgat tgttgcacca tcttttaatt
    20041 cggaaacatc tttgactttt ttagagtaca agcccattgg ttcgatgtgg acagcaccgg
    20101 cattgacaaa gtcatatcct ttttctttga tttctttgtt caaataagga atatgctgga
    20161 agtaattggc atcaatgtcg ccttcttcca aagattggtt cggtaataca tagtcatcga
    20221 atttgacgat ttcaagatcg attccttcat ctttcaataa tggtttcaca tgttccaaaa
    20281 tctctgcgtg cggtgtcggt gaagcgccga ctttcaatgt cgtgtcgtct gctttatttg
    20341 ctgaatcttt gctgtcgctg ttgttaccgc atgctgctaa tcctacagtc agcaaaagcg
    20401 ctgctgcaaa tccaaaaatt ttctttttca tatcctacat ccccctatat cctattatct
    20461 tttgtctgtt ttcttagtta agaaatcacc gattccttga acgataaata cgattagtaa
    20521 aataattaaa gtcgcaacga atgtcactgt tagattacca cgctggtagc cttcctgcca
    20581 agcaagacct ccaagtccac ctgcgccgat cgcgccggcc atcgcagtaa atccgatcat
    20641 cgagatcgtt gtaactgtta atccagaaat caatgcggga atactttcag gtatcaagac
    20701 cttccagatg atttcccagt aacttgctcc cattgcatct gctgcttcca gtacaccagg
    20761 gctgacttca cgaaaagcaa tctctactag acgggcataa aatggtgctg cggataaaac
    20821 aagagctgga atggctgctt gcgcacctag catagtgcct acgattgctt tagtaaatgg
    20881 aatgatcaaa accatcagga tcataaatgg cgttgaccgg aaaatattac tgatgatcga
    20941 tacgattcca taaatgattc gagcatacgg tttgtttttg cgtccaatag agtaaaggat
    21001 caatcccaaa actaatccga tgatcgtcac taagaccatt gagattaatg tcatatatag
    21061 tgtatcaagg atagcctgat tcatcgtttc cgggttgatt tgtttaaaat ctagatatgt
    21121 ttctgaaaag cttttatcca cgatggatca cctcaattcc tactccttgt tctttgatga
    21181 acacttctgc ttgatctaat tctttggttt caccagtcat caagacagtc aatgaaccaa
    21241 aggaaccttc tttcacttgt ttgatctttc catacacaac gttgacatcg atgttatagc
    21301 gtcgaatcgc ttgggaaatg actggctcgt tggcatttct ttcgctaaag gtcaaagttg
    21361 ccaaacggcc gcttggattt tctttgatga gttcagctaa tagttctgtc gaatcagctt
    21421 ctggttcgat gtcttgttgt acaaagcgtt tggttacttc ttttttcggt tgtctgaaga
    21481 cagtcaatac gtctccttct tctacgactt tccccaactc catcacagcg actttgttgc
    21541 agattttgcg gatcacattc atttcatgtg tgatcaagac gatggtcaaa ttcaatttct
    21601 tattgatcgc taacaataag tctaatactt cttctgttgt ttgcgggtcc aatgcgctag
    21661 tagcctcatc acaaagcagg atctcaggat catttgccaa tgctcgtgcg ataccgacgc
    21721 gttgtttctg tccgccggaa agttgtgaag gatatgcttg tccgcgtcct tctaacccga
    21781 ctaaacgcaa cagttcttct gcccgttctt tacgtttgct ctttggtacg ccagctaatt
    21841 ccagcggcag ctggatattt tcaagtacag ttcttgacca taacaggttg aaatgctgga
    21901 agatcatacc gattttcttt cggaatgtac gtaattcttt gttttttaat tttgtaatat
    21961 cttgatcgtt tacgatcact tcgccgctcg tgggaagctc aagtccattc aggagacgga
    22021 ctaatgtact ttttcctgcg ccagaatagc cgacgattcc ataaatatcc cctttttcaa
    22081 cgtttagtga aacgtcattg acggcttgga tgtttccgtt tttcccattg aatgtctttt
    22141 tgacattcgt tagttggatt aatgacatgc cattcacatc tttctcttat aatttttcaa
    22201 acaaaaaagc cttcgccctc ttgccttaag caaaaggacg aaagcttgaa cttccgtgtt
    22261 accaccttga tttaccgtta cttcgcaata acagcctctt ccagtacttg gacttagctt
    22321 ctttccgtat actgtcgcgc tgtaacgggc actcccgtag taagtttgct tacgctcgct
    22381 tactctgctc taagaccatc ttccatctca ttttcgttac ccattttcag caaacagggc
    22441 tctcttcaaa cgtccgtgac atgtactctt cttttcaaag ctttctcgtt tcatatagga
    22501 ttgcttatga ttatagcaac tggaagaatc agtgtcaact tttttcaagt gattttctga
    22561 ttttataatt cgtcaaattc ttttggatca acatctttga aacttaagat ccacgcattc
    22621 atttcatctg aatcattcaa gatattgata tcttcaccga ttttatcatt aacagaagaa
    22681 actgtacccg ttagcgggct ggcaaattca ttgaccgctt tttccgcttc aacttcgatc
    22741 agaggttcat ctttttttag cgattgtcct gcttttggca gattggcaaa cgtgatgtct
    22801 ccaagttctt cttgcgcttc atttgtcaaa ccaacacagt attcttttcc attaaataag
    22861 atccaaaggt tgtccttttt cttcaaatgc ttgcctgcca ttttatatca gttctccttc
    22921 ataaattttt tcattgaatc caattgcaac aagctggtcc tctcgtaaga tcagtggtcg
    22981 cttgatcagc ataccatctg tcgataagac ttggctcgct tttgaagccg taaactcgcc
    23041 tacttgatct ttcagtccaa gttcccgata tttcatcccg cttgtgttga acaggcgacg
    23101 gattggtact tgactcgttt ctagccaagt ctcaatcgtt gaggccttcg gtacttcttt
    23161 gatcatatca acggtttgat aactaacgcc atgctggtct aaccacgctt tggctttttt
    23221 gcatgttgaa catttcgggt accagtaaaa ggtgtacaat tttcttacct ccttgaagat
    23281 cttgcaggtg cttcattttg gtatctcatc gataatatca acccgatacc gatcatgttc
    23341 cctaaaatcg aggatcctcc ctgactaatg aaaggcaatg ggatccctgt taaaggaagt
    23401 aatccgatat ttgctccaat attctcaaag acatggaaca gcagcatcat gatcaaaccg
    23461 cttgcgatat aggcgtaaaa ttcattattc gtatcgaaac acacccgaat catacgatag
    23521 attaaaataa aatacaagaa aatgacgaat gcaccaccga taaagccgaa gttttcaccg
    23581 ataacggtaa aaatcatatc ggactcacga acaggcacat agatattgct tacgttgaat
    23641 cctttaccaa acaagccacc ggtaccaatt gccaaaagtc cttgggccgg ctgataactc
    23701 attcctgacg tatcatggaa agggtccagc catgaatcaa tacgtgcaaa ctgataagat
    23761 ttgaatccaa ctttataaag caagtctctt ccgccttcag tcgtaaccaa gaagatcgtt
    23821 cctgctccaa cgactactgc caagattact acaggtgcga tgatgcgcca agagattcca
    23881 gacatcagga aaatcccgcc aaagatcgca agaaagacaa gcatcgttcc aaagtcatct
    23941 tgggccatga tcaatgctaa aaccggtatt gtcacgatca agagcttccc aatcagccaa
    24001 aagtccgatt tcatcgtccg ttcttttact tgcgtattat gtttagttac gatcagtgcc
    24061 atcatcaaga tgtacgcaat cttcatcaac tctgctggct ggaaagtaaa cgcaccgaat
    24121 cgaaaccagt ttttagaccc tgttgaagca gctaaattct gatcatagaa tttgagcaag
    24181 agtcccatta ccactaaccc caaaccataa aggtaaggag tcagtttcca gatccatttg
    24241 gaattcaaat gcatgatgac aacgattgct gccgctccaa ctaaatacca gacaacttgc
    24301 atccctacgc ctttcaagac tgctggattg ttcggatcat ggctaagtgc tacatataat
    24361 gagagcagac caatcaaaca taacagaaag actggtaaaa tcacgccata atcaatacga
    24421 ttatcgttcg aagcttttaa ttttttttcc atgtttcatc ccttttctta aaaaccatac
    24481 tgctgattat tatagcggtc cagttagata atggaaagtc tttccataga catttgggaa
    24541 aaattaactt tccgtttgtg cagttgcttg agcaaatgca gtacaaaagc ctactgctta
    24601 tctttagtgt atcatagaac tttttttgat acatgcaatt atctaccagc tgagattctc
    24661 ctcgctgtga gaagtttctg tgctttcatt gtatcgaagg atctcttcgg caatctctag
    24721 cagctgatca gaaaccagat tggttcgttg gatgaaataa aaatatcgat ggaaattcaa
    24781 cggagtcatt ggcacatttt ctggaacaga gcgcttagac aaaatcgagc gaccgattcc
    24841 ttccttcagc aacgcaacaa ttacatcgtt acttttcacg atcatcttct tatcttggat
    24901 attcatctct tcaaaataac gctgcgtgta atgaaaaaca ccagagtttg cttctcttac
    24961 aagccacaat ttgctttttg ggtccccagc gatgactagc tggtcttcca tcaaagagta
    25021 tctttgtacg ccggaagtct ctaatggctt ttcgataaaa ccaaaatcgg attcatgttt
    25081 cgctacttgt tctaatgatt catgagaatt cgtgatttcg atctcaaaat gcactttagg
    25141 aaaccttttg atcagatgtt tcatcaactg aggcaaaaga tagacagcaa aggtgtggga
    25201 agcaacgatc cgacatactt cttcttcatt ttgttcattg agcaattttt gctgagtttc
    25261 ttcccattct tctaacaaaa ccagtgtccg ttcatataat aagtcggctt gcttagttgg
    25321 aagcatctct tttcttccgt tacgttgaaa aagatcgata ttcaattccc gctccaactg
    25381 tttgatttga ttcgagactg ctggttgaga taaaaacagt acttctgctg ctctggaaaa
    25441 atttcttgtt tcatatactg ctcgaaaagt cgttaataac ttaaacatgg caccacttcc
    25501 ataacttttt atgataatta ctataaaaac tatttgattt aaatatacaa aaaaccatct
    25561 ataatagaaa tgtacaacaa aacagttgct gatccaacta gtaacttaga tgaagacaat
    25621 cagctgtctg cttgctcgta atcatacatt cctattcatt ttacaatgta ttcgttcatc
    25681 ttggtactaa aatctattaa ataaaaagga gaatattata tatgaagaac tttttgaaaa
    25741 ttattccgat cccgatctgc gggttgatcc ttgggttagc ttcccttgga aatctgttta
    25801 aagactatca ccatgttgct ttaggcaatc taactggcgg tatctctatg attcttatga
    25861 tattcatttt tgttaaattg tttatcttat tcgaacacac gaaacaaacg ttgcatgatc
    25921 caatcatcgc ctccgtttca ccaactttta cgatgtcact catggttatt tgtacttatt
    25981 ttgtttcata tgaaagtatt gcaccaattg tcaaattcat ttggctgtgc gctgttatct
    26041 tccaagtgat ccttgtcttt tatttcaatt atcaccatgt tatcaaagct gatctttcaa
    26101 ttgaagcaat ttatccaagc tggtttatca tttacgttgg atttggggtc atcactgtaa
    26161 ctgccgggaa cttcttccca cttattggaa aaattttctt ttggatttca ttgatctgct
    26221 atgcgttctt attgccgatc atcatcaaac gtgtcttttt cgtaagaaat atggctcatc
    26281 cgacacgtcc gctgattacg atcgttgcag cacctggttc tctttgccta acaggttatc
    26341 ttaaaaactt tgctgaacct aatttttatc ttgtcgtagc attgttcgct ttatctcaag
    26401 tattgtattt cgttgtgctg tctatgcttc cacgtttgtt caagcttcgt ttttatccaa
    26461 gctatgcagc ctttacattc ccgcttgtta tctctgcaac agctatattt actactgttc
    26521 attacttcaa cagtttaggt atctatagta gcgtattgga tttcttaaaa gttgcggaat
    26581 gtctgtttgc aagtgtagtt gtcttctacg ttcttgctca ttacgtacgt ttcttaatta
    26641 aagaacatag caaacatgga aaatttgttt ctaaaaaaat cgcttaataa tcgattcaat
    26701 aggttgtgaa aaagctgttc tgcatcaagt aataagaacg gccaaacaaa aacagctgtt
    26761 catgtttttg tactggttgg gcttattacc gcagatgcaa gcttttgaac accgtttacc
    26821 aagaggtcgt aaaagaagtg gtcagcttca agaaataaga aggaatttac gaaaattgct
    26881 tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag ctacttctgg aacaccgttt
    26941 attcgaaaca agaggtcgta caagactttt gtcacgacct cttgttcttt tgtcaaaata
    27001 ctggtttagt gctactatgt tcgagtatgc ttttagtatt tattgacgaa aggaaccgat
    27061 caaatgaaat cattgtcaca tccaataaaa tctgtaaagg attcagcggt ccgcgaaatc
    27121 ttacccggtt tactgctttc ttttgccatc gctgccttca gcaggcttct tgctatttat
    27181 ctgccacagt taggtggagc gactattgct attttattgg gtattttatt aggaaatact
    27241 ttttttaaac agcctgttct agcaatcggc acaaaatttg ctgaaagcaa actattagaa
    27301 ttctctgttt ttttactagg tgcaactgtc acagctcaaa cgattgctca aattggtgta
    27361 aaaggaattg tttttgtgtt actgcaaatg tcagtcacta tcatcggtgc ttacttgatt
    27421 ggtaaaaaac tgcaattcag cgatacttct tctttgatga tggctggagg aaacgctgtt
    27481 tgtggttctt ctgctattgc ttcaatcgcc ccttccatcc atgcgaaaga ggaagaaaaa
    27541 ggacagatca tcacactagt caatctactg ggtactgtga tgatgttgac tctccctttt
    27601 cttggattac agttgtttgg tggaaatctc attgaaaaaa gtgcactttt gggtggtaca
    27661 ctccaatctg ttggtcaagt agtcgctggg gcaagcttac ttgacaattc tgttgtcgaa
    27721 ttcgccatgc tatttaagat tctacgtatt atgatgctcg ttgttgttgt ctatctgttt
    27781 gaaaaattca tgcacaagaa acaaccagct ctgtttgaaa cgccaactga tacgcagaaa
    27841 aaacgaaaat taccgcttcc ttggtatgta ttagggtttg tgatcttttg tttggtcaac
    27901 agcttgtttt ctttacctgt agttattgac caatcggcac attttatcag cagctggttt
    27961 gagatcactg ctttagcggc aattggtctg cgtttagact ttgcaaaatt catgaaagaa
    28021 ggtacacgct tcttatctta tggattagct gtcgggcttc tccaaacagt gatggcttta
    28081 ctatttattt ggctgatcaa agtttagaat gaacatgaaa aaacagttgt gattctcgca
    28141 tggaacaatg tccgaatcac aactgttttt aattttgcag atatccttct aacaacaaca
    28201 attggcgttt gatttcaacc ccatctattg cgtttcccat atatcctgtc agttttccat
    28261 tttgcccgat cactcgatga caaggaataa cgattggcaa tggattggtt cgatttgcct
    28321 gcccaatcgc tcgcacagct ttcggactat caacagcaac ggctacttct ttatacgttc
    28381 ggatttctcc ataaggaatg gtcgacaaag ctttccagac attttgctga aaaggcgtac
    28441 ctctctttat agataaagga acatcaaatt cttttctttt tcccgcaaaa tattcttcaa
    28501 actgttcttg tgtgcgcgtt aaaattcgct gattcgctga ttcgctttct gaaattggct
    28561 gaaaagatac agcagtcaat ccggattcat ctgcatctaa ccataaaaag ccgataggtg
    28621 tgtgtatttt cattttgttt gctcctagtc aatagactgg aacttcctcc tttttctcta
    28681 tccaaaacta cttgccaact aataaaaatt gttcttaaaa gtttgataaa ccgaggaaac
    28741 atggtaaact aaatacgtta gtttacaaaa agaatacctg ttcttttacg taaaatcaaa
    28801 ttttaaaggt gttatttaag gtttattaaa ttttgaatgt aaaccatata taaacatacg
    28861 attgaaagga tagaaacgat gaaagtatca attgttgtcc catgttttaa tgaagaaaaa
    28921 actgttcctc ttttttttga tgaggttgaa aaattcaaag gtgcccatga gttcgaatat
    28981 ttgtttattg acgacggatc aaaagacggt acgttagcag caatcaagaa gctagcctca
    29041 gcttatcctt atgtccgctt tgtctcattt tccagaaatt ttgggaaaga agcggctctg
    29101 tacgctggat tgcaagcttc tacaggagat ttagtgaccg tgatggatgt tgatctgcaa
    29161 gatccgcccg aactgcttcc tgagatgatc aaccggatca ctacttctga tatcgattgt
    29221 gtcggcaccc ggcgttcgac tcgtgaaggc gagcctgcga tacgcagttt ctttgcgaaa
    29281 aaattctacc agttgatcaa taaaatcagc gatacagaaa tggtcgatgg cgctcgtgat
    29341 ttccgcttga tgactcgtca aatggtggat gccgtcctag aattaacaga atacaaccga
    29401 ttttcaaaag gattatttag ctgggtcgga tttaaaacag aatatatttc ttatgaaaac
    29461 cgcgaacgtg tggctggcga aacatcttgg tccttctgga aattattcaa ctactcgatt
    29521 gatggtatcg tgaacttctc ggatgcaccg ttaacgattg cttcatttat cggcgctttg
    29581 tcttgtgtcg gttctggtat tgcaattttg ttcattattt tgcgggcatt gttgtttggt
    29641 gatcctacat caggatggcc ttccatggtc tcgatcttcc tgttcattgg tggaatccaa
    29701 ttgttatgtc ttggaatcat cgggaaatat attgggaaaa tcttcttaga aacgaaacag
    29761 cgtcctgttt atatcataag agaaacagaa aaagtgaagc caaatgaatt gaagcctcac
    29821 caataatata cgtcaaatga agtaaacatt tttttaaatg aaaaaggact gtgacaaaag
    29881 tcttgtcaca gtcctttttt ccgaataaat ggtgttccag aagtagcttc ttcggaaata
    29941 agccgaaatt tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    30001 gctgaccact tctatcacaa cctctttcat atcttattac ttcttcattg ctgcttttag
    30061 tgctgctgct aatgggcttt cttctggttc ttctgcttgt gcatattttt tcagcaagcg
    30121 tcgttcttca tgtttggtca ttttcttctt ctgctctttt ttatcaagca atttttctgt
    30181 cgttccatcg tatttacaac ggaaataagc accgttttta ccttcgatga tttccatttt
    30241 ccggtgacat tgcgggcatc gatgattaga gacttttgga tcttttcttc tgcggtagtt
    30301 gcaatctgaa ttggtgcaga catagatttt gccgtcacgt gtgtttttct cgcgcagatt
    30361 ggccccacat tctgggcatt tcttttgggt aatcgagaaa tcttgatatt cttgtttgct
    30421 tgatttgatc tcattcacca agcgttttgt ttctttttcg attccattca agaaggttcc
    30481 tgcttgtttc tttcctgcag caatagcttc aaggtctttt tcccagcttt ctgtcaaatc
    30541 tggtgttact aaagagggat ttaccaatac taataattgc ttacctttag gagatacttg
    30601 cagtccttga ggggtacgtt ccatcagttc agatttgatt agtttctcga taatctctgc
    30661 acgcgtagct ggggttccca gactgtattt ttccatttga ccaagcaagc ttgcttctga
    30721 caatggttta ggcggtgcag atagttcttt tttgatggcg aaatcgggat tgattctcat
    30781 tcctttttcc catttgactg tttccgtctc agtttcagtt tcgcctttcc atcctgcttg
    30841 gacgacacga ttttgccgaa aaatgaatcg ttctttacca aattcaaccg taacttttgt
    30901 ttggctgact ttatggggtt gagcaaacag tcctaaaaaa cgagagacaa tcatttgata
    30961 gatttttcgc tcttcattac ttaatttttc ataacgtgct ctgttttcag ttggcaaaag
    31021 tgcatggtga tcggtcactt tactgtcttg gaatactttt gtctgttgga cgatggctcc
    31081 gtttttcaaa tactgcttga cctcaggagc aaagtcgctg actgcttgca atcgttcttt
    31141 catcgtactt ttcatgtcat ttgtcagata tttgctgtct gtacgcggat aagtaacgat
    31201 cttatgggtc tcatacaaac tttgtacaag acttaatgtt ttctttgcag aatagccata
    31261 gcgttgattg gcttctcttt ggatctctgt taaatcataa ggcaatggcg cagattccgt
    31321 ttttaatttt tcttggactt ctgtgacagt tcctttgctt gtactgatca attgaacaag
    31381 tttttgtgct tcttcttgtg tttttaaagc aaattgattt ttttgaagca ttttggcttg
    31441 ttcttttcca gcttgcaacg tgatcgtgaa atacgtttgt ggacggaact gctcgatttt
    31501 cttttcttgg tctctcacta atgctagtgt cggtgtctgc acacggcctg ctgataaatt
    31561 atccgcgtac ttcacagtta aggctctggt cacattcaat cctaccagcc agtccgcttt
    31621 tgcccgggca agagcagatt catacaatgc atcatattct ttcgcaggtc ttagttgctt
    31681 gaatccagtt ttgattgctt tatctgtttg agaagagatc cataaccgct tcactggttt
    31741 attgaaatgc acatactcta agatccagcg agcaacaagt tccccttctc ttccggcatc
    31801 tgtcgcaatg actgcttctg agacatcttt tcgctgagcc agctgcttga ttgcttttaa
    31861 ttgatgtcct gttttaggaa gtggtttgat tcctagtttt ttagggatca ttggcaacgt
    31921 gtccatttgc cagctctgcc attccttatt cagatcttcc ggcattttca atcctaataa
    31981 atgaccaagg gcccaagtaa cgatcacctt gggtccttca taataatttt tgtgcttttg
    32041 attagcacca agcaccttgc ttaggtcttt cgcaacgctt ggtttttccg ctagaattag
    32101 ttgtttcata aaattccttt ctgctttcta ctgtgatggg ctgatgattt ttcaacaacg
    32161 caagtccctt gtattgctgt aaatcatcgt cacactcttc acaccagcgc tcatctccgt
    32221 cattccaaaa ggcgctgaga aagttacttt ttgcattgat atattcataa ttttgatgga
    32281 tttcgttcca ttgtttttcg tacgcttgtc gtgcttcttc gaaagactcg aatgtttctt
    32341 cttcttcaat atcttcttcc cagtcttcaa aaaaccacca aggctcattg tccccgaaca
    32401 tggtaattac ttgatacata ctcgtgctcc ttctttcagc ttttctagac tcatcttagt
    32461 cacttttcaa gaaagttgca agaattttct cttataaaag ggtcatttaa tgaacatctt
    32521 aaaattgtta caaatgaatc tgattgttta aggcaaagta gcgataaagt tattgatcat
    32581 ccaaaaatag ctgtcttctg gatcgattgt tggttctttt gtaaagtatc ctaaaaaacg
    32641 taaggaaaga taaccgtgga tcatactacg aagttccctg cttcgatgaa ctttttcttc
    32701 tttcgttaat tgaaaagcct caaatatctg caaaatgatc tgattcgttt catggattcc
    32761 atctaataaa acagcttcat tggtatgcgg tacactgatc agtaactcat acactgcttg
    32821 atttgaaaaa gcaaaggatc gataagtttc tgcatagatc tgcagtgctt cctgaccact
    32881 ttttcccaca agagcccgtc gcagctggtc attaagttcc tgcagaagtt tcgctgttag
    32941 cgctgttttg acatcacgaa tatttttgaa atggttatac agcgagggag ccttgatatc
    33001 caagcgtttg gctaaatgct gaaaggttat ttgctgaaca tccatctctt ctgctagttc
    33061 tcgaaagcag tcgatgattt tctcttgaga cagatttctt tttttcattt ccatgtttcc
    33121 tctcataaaa taaatccttc actctttcag tttaccacga aaaagaaaga gaaaaaagag
    33181 actttcattg ataaactaca tattgtagtt tataataaag agctgtagat gaaaattttc
    33241 agaaagaagg agtctaattg gctgcaagaa taaaggaaaa attatttagg aaaagagaaa
    33301 cttgggaaca aaacttgttt gtcttatggt ttggaacatt tatggctggt atcggattta
    33361 gtttagtcat gccttttatg tcactttaca tagatacgtt aggtaattat agtacgtcac
    33421 aattgaactt ttggagcgga ttgacttttt catctacttt cttggtgact acgcttatct
    33481 ctccttggtg gggaaaatta gccgaccaaa aaggaagaaa attgatgctg ttgcgtgctt
    33541 cattaggaat ggcaatcgtc atttctttga tgggttgcgt gactagtgtg tatcaattag
    33601 tcgcattgcg tctgcttcaa gggatttttt ctggttatat cagtaatgcc actgcccttg
    33661 tcgcaactgg gacgccaaaa gaaaaaagtg gtcaagttct tggaacctta gcaactggtt
    33721 ctgttacagg aacattactt ggaccgcttc ttggcgggat ctctgcttca gcgtttggct
    33781 atcgccctac ctttttcatt acagggatca tcttattttt cgtcttcttg ttgagtctgt
    33841 ttttcgtcca tgaaaaattt gtcccagtga aaaaagaaaa catggtttct gccaaacaga
    33901 ttttcaaaga cttgaaatat ccacacgtcg tcatcggtat gttcgtcaca acgatgatca
    33961 tccaagcatc caacaattcc attagtccaa tcatcagtct gtacattcgc caattgctgc
    34021 atggacatgg gaatgttacg ttgatcagcg gaatcattgc ttcgatacct gggattgcca
    34081 ctttgatagc cgctccaaga tttggtcgct taggtgacaa gattgggagt gaaagaatac
    34141 ttgcgattgg tttgggtttt gcgattctgg tttatatccc aatggcattc gtcacgaatg
    34201 tttggcaatt agctgcctta cgttttttga ttggtatctc tgatgcttgt ctgctccctg
    34261 ctgtccaagc attgatcaca aaatattcgc ctcatcaagc tgctggacgg atcttcagtt
    34321 ataaccaatc tttccaagca actggtaacg tagtagggcc tatgatcggc tccagtgttt
    34381 ccagtgcatt tggttatcgc ggcgtctttc tttcgacttc tcttcttgtt ttggtcaact
    34441 tcttgcttgt acgacacaat acacaagaga tccatcagca agaaactgca gaagaaaaag
    34501 cttcaggagt ctccatagct tcagggcact ctccttctca tagacaataa gcgtaaatga
    34561 aaaacactgc ttgaacagtt gtcacagact gtccttgcag tgtttttgtt taggcctgtt
    34621 ttttcaagaa ctcagataag aggaataatc ccttttccaa ggtttctttt ttacaacagt
    34681 aacctagtcg ggcatgcttc ggtaaatcaa aggcacttcc tggtactaat agtactcctg
    34741 tttcttctaa taaattgata caaaatgtct ggtcatcttc ttcgatggct aatttaatga
    34801 aagaagtaga gacgtaattg ggagcgacaa gttcaacttt cggttcattg gctacccatt
    34861 gttttaaaat cacaaggttc tctgtaatga tctttttgtt tcgcgccaat attttttctt
    34921 tattcttcaa tgcatgtaca gcaagatcat ctgacaggac tccgccgcaa atcatcgtgt
    34981 agtctcgata ctttcgaaaa acttctgcca actcaggtcc agtagctgtc cagccaatac
    35041 gaatacctgg aatggagtag gttttggata gggaattggt tgctatacct ttttcataga
    35101 catctacgat cgacaagaat tcacctttat ccgttaaagg cgcatatact tcatctatca
    35161 atacatatgc atctactgta cgagcaattt ctgcgatttt ttctaaagtt ttccgatcta
    35221 gcaatgtgcc tgtaggattg tttgcactat tcaaacagat gatttttgtt tcaggtttga
    35281 ctaaggcttc tagctgttct aaatcaaact gccaatcttc ttcttccttc aaatgaacaa
    35341 agtcaacagc ggcacctaaa gatttgggga tgtcatataa ttgctgataa gtaggaagca
    35401 tcgaaacaac atggtctcct gcttccacta acgcgtatag agctaaaaga ttagcaccag
    35461 tcgctccatt cgtttgtaag atgttttccg gatcgacggt ttgataaaga gaagcgactt
    35521 cttgtttgaa aacatctgat ccttcgatcc agccatagtc caatggttcg tttttgcgtt
    35581 tttcgaaaaa tttacttacg ctagtcccat ctaagccaac gagttcgtct aatgtcaatg
    35641 cttcgatcga gctttgtgca atatcatata ccgctttctt ttcccattta tttagccatt
    35701 cttctacacc gaaatttgcg attttcatgt ttctttcccc cttatatctt gatccagcct
    35761 acagcaagca acccgattga aagcagtgcg gccacacaaa tcagcccaat cattactttt
    35821 tcttttcccg taatttgatg tttggtttca cgacaagcga tccagtagaa gcaaaaacca
    35881 ggaagatagg caatactaca taaaaggaca taagaaaatc ctgctaaaat gatgcccatc
    35941 aattcaaaaa ctacagcaat cccaccgatc actacttgtt ttttgattcc ttcttttaaa
    36001 gaaaactgga cttgatagat cccgacaagt agataacaaa tcaaaattgc cgctgtacat
    36061 aaagaatagg caaattgata ggcataatca gtaattaaga aagtcaataa gaatagatta
    36121 gtcaagattg cagtaacaac taacgaataa gttggggcat tttttttatt cgtttttccc
    36181 caacctttcg gcaacagacc gtctcgagcc atcaacatcg ttgtttctgc tgggagcatc
    36241 gtccaagaca accaagaacc aatgatcgaa ataatcaagc cgatattgat cagcgctgct
    36301 ccccaatttc ccacgattcc ttttaaaata tttgccatag caggttgtga aatagttgct
    36361 aactcttctt gagataagac gccgtatggc aagatcgaag caaggatata gataaacaat
    36421 aaacaaagca gaccaatgat cgatgcttgc tgggcttctg aacgtttctt cgcgcggttg
    36481 gctaaaacac ttgcgccttc gatccctaca aagacccaca tcataaccat caaacaacct
    36541 ttaatctgca accagatcgt tccttgctgc cctgttccat tcactagatt atcagatacg
    36601 ttaccccaaa aatcagcagt gaatatattc actttaaatg cgataaatac aaatattaaa
    36661 aataggaata atggcactaa tttacagatc gtcacgattg tattgatgac gctcgctcct
    36721 tcaactccat tgtttactaa taaagtcaga ccccaaataa aaatacttgc aaataaaata
    36781 gaaggaacat tttgtccacc tttgaatatc gggaaaaatt ctcccatggc gctcatcagc
    36841 atcgttgcaa aagcaacatt tcccagccac gcagacaacc agtaacccca accactgatg
    36901 aagccaccta atttaccaaa tgaagcttcc gcgtaaccga aaataccacc atctagatct
    36961 ggacgctttt ctcctaaatg attcagcgat aataccaaag ctaaaatacc aatcccaacg
    37021 attatccatg aaaggatcgc tggccctgga gctgcagaac tagccagatc acttgtgatc
    37081 ccaaacacac cgcttccgat tgacgaactg acaaccagag caaccagtcc ccatttgcta
    37141 atacccgtcg atttcttttc catttccatc accctcactt ataaaattga acaaatcact
    37201 tgcaaaagat tcccttctat tttgcaactg ctcttgctta acaaaaagca actttattca
    37261 tattattgga tattatgaac tttttacaca agtatttcaa gtataaaatg aataaaaatt
    37321 aattttattg caaaaaaaca gctatgctat ccaaaagaaa aggtgtttct tttgttagcc
    37381 atagctgttt tgattcattt aatatcgctt aaacgtattg taaaactttt gtttcttgat
    37441 atgcgtggtc gatcaaacca ccacccagac attccattcc atcataaaat acaactgctt
    37501 gtccaggagt gattgcacgt acaggttcgt cgaatacgac ttctgcacga ttatcatcca
    37561 ataagcgaac tgtcacagga acgtcttgct gacgataacg gaatttcgct gtacacttga
    37621 attcttttgg cattggttca ttcgtcgtaa agtggatttc acttgcatcc aagcttgtgg
    37681 catacaatgc aggatgatgg aacccttgcc ccacatataa tgtgtttgtc gctagatctt
    37741 ttcctacaac aaaccagggt tcttgcgaat ctcctccgcc accgatccct agtccttgac
    37801 gttgaccaat cgtataatac atcaagccag catgttgtcc tttgacttca ccatcaagag
    37861 tgaccatatt tccttttttt gctggcagat agttgctcaa aaattgtttg aagttctttt
    37921 caccaataaa gcagattccc gttgaatctt ttttcttagc agtcgcaagg cctgcgcgtt
    37981 cagcaattgc ccgtacttct gatttttcca tgccgcctag agggaacatc gtttttgaaa
    38041 gctgttcttg tgataattgg ctaaggaagt aagtttgatc tttattattg tctactccac
    38101 gaagcatgtg gaccacgccg ttttcatcgc gagtgacttg cgcataatgt ccagtagcta
    38161 cataatcggc gccaagatcc attgcataat ccaagaatgc tttgaatttg atttctttgt
    38221 tgcacatcac gtctgggtta ggtgtacgtc ctgcgcggta ttcggctagg aaatattcaa
    38281 atacacgatc ccaatattct ttttcaaaat tcacagagta ataaggaatc ccgatttgag
    38341 cagctacttt cgctacatcc ttataatctt ccgtggccgt gcatacaccg ttttcgtccg
    38401 tgtcatccca atttttcatg aatattccga tcacgtcgta tccttgttcc tttaacaaaa
    38461 gtgctgttac agatgagtcg acaccgccgc tcatccctac gacaacgcgt gttttgctgt
    38521 tgtctgtcat gatatcacca tcatttcaat tagattctga aacatctacg agttgaaggt
    38581 cgcaactttt cagtatttta cattatacgt catatttctg aaaatttcat cccttaatta
    38641 tcaagtcgta aaaatactgt tctactggac ctattcagta cacaaacatg atagtcaacc
    38701 aaaaaatcac tcatcttttg agcattcgat ataaaaaatt ggcatactca taaaaagggc
    38761 cagcctttcg gcaataagga ataattttat aaattgtgaa aaactatttt tcaaaattgc
    38821 ttcttatcgc ttaaagctgc acgtctcatt tacaaccttt tctttttaga tgttatgagt
    38881 tgctcagata agtgattttg tttactctaa gaaaaaaggg aggcaaaaga tacatgaatt
    38941 actttatcag tgatatgcac tttttccatg aacgcttatt aggaaaaaac gactttgctc
    39001 cgcggctctt tgcaaatgtg gatgaaatga accaacagtt gatcactagc tggaatgcag
    39061 taataaaaga aaccgaccat gtttatcatc taggcgacct tgctatgcat ccgcaatatg
    39121 aaaaagcaaa tgcagaaatt ttggaactgg tcactcaact gcaaggaaca atccacttga
    39181 tcaaagggaa ccatgacagt cgcgcttttt tccgttattt agaaaaaaat gatcctaggc
    39241 ttactgacgg aagtcccaaa ttttattttt atgatgtagg tgccatcgtt aaattcgacc
    39301 atcaacaata ttacttgact cattatccga tgttgctcgg gcctaacgac actatccgca
    39361 atcttcatgg acatatccat cattacagcg tacctatcga gaacgatgtc aatgtaggcg
    39421 tagacgcacc ggaaagagaa ctcttaaagg aaaaactacc atttggcact ccgttatctg
    39481 agcaacaaat caaagaaatc tatgaagcaa agaggaagta cgataggtcg tgaaaaaact
    39541 gccctatatc aagtattaaa caaataaaga taattactca tatttttcat ttgagtaggc
    39601 ttattgccac aggaacatta ggatcagaaa tggagttgta acaagacttc tgtcacaact
    39661 ccattccata ctattcgtct ttttgctcat ggtgttcttt taccagtttt ttctgtaatt
    39721 ctttatcata atttcgggca gctgacgtta aaaataaaac gattccgcat aataaaatcc
    39781 cgattccgga aaacaagaac attttttcta cccctaaacg atcagctaat ggtcctgcaa
    39841 ataataatcc aattggacct gccaggttca tcaaagagtt gaagttccct aagacacgac
    39901 ctaaaacatt cgattcataa ctctgctgga tcattgccat cagcagtgta ttgaaatatg
    39961 gcgttgcaca acctgctcct gcattcaaga taagaaagta caagaaccct tgactatcgt
    40021 ttggaaccaa tccgcttgca ccgatcgtca ggcccataat gatgtaggct ataataatag
    40081 gtttcattcg gtctttccat gttcctataa aactgatcag tgcaccgcct aagagcattc
    40141 cgactgcgta gactacttcc actgctcccg cctgtccaac ggaaccacca aagtaatcta
    40201 gcgtcatcaa tggatacaga ctgattgctg gcatgaacaa cagcatcaca aatgcaccat
    40261 tgatcgttat gtaccataac cctttattat ccatcaattg ctgcagccca aattttgcat
    40321 ctttaaaaat agtaagcgga acttccaata tttcaggaga aacttttggg atcttcacaa
    40381 aaatcaataa gccgacacca aaaactgccc ccaatacatc taataaaata aggtaattga
    40441 caggaacgac tgaaaacaaa gccgcaccta gagctggcgc aatgatgaaa ttcgctgatt
    40501 ggaccattcc taactgtcca ttcgtccttg ttatgtgaga agatggaacg attgtcggca
    40561 taatcgactg gatcgttggc atttggaatg tttgtgcgac cgaacgcata aacaaagaca
    40621 caaaaactag ccaaatcggg aaggattctg aaatcgttcc gactactgct aaaataagcg
    40681 cgaaaatcgc tacaataata tccgtgacaa tcaaaagagc ttttttatcc cagcgatcca
    40741 ctagcggtcc tacaaatggg cttagtaaaa ccatgggaat cattcctagt aaagtagcaa
    40801 aactcaaaat tgtcgccgaa ccggtttctc ttgtcaaata ccagatgatc gcatattgga
    40861 cgaccatact agtgattcct gacaaaaact gtcccgataa aaagaacaaa taatttctct
    40921 tccaattcgt taaaacgacc gactgttcat tttccataaa catccctctt ttctttttca
    40981 ttttgtatag cgtttgcaca acaatcatta tacgggattc ttttttcaaa aaataccttt
    41041 ttccctaaat aacaatcgtt tcaatttaaa tttctttact tagaaacaat aaatcagcaa
    41101 aatattaaaa ataacaacat gtgttaaatt taaaaataaa aaagacaact aatttgcgtc
    41161 gtccttacaa agttagtcat ctaacaatag gccgtttcaa aactagttgt ctttttatat
    41221 ccacagatca ttcgactttt tcgaataacc cacggctaat catcccatcc atcagaaaat
    41281 aaaatttatc ttggctcatt ttctgttttg gatctttgaa aatattgact gctttcaatc
    41341 catttgctgt agtgatcgac attttcaatg tttgaatatc ttttgataca gtgattttta
    41401 atttgaatcc ttctttgctt tgcggcgtgg catctaatgg tcggatcaat tgataattgc
    41461 ctccgtttgt ttctgtaaat ccattatcgc gcaatgtata tctttttgca tcaggatgca
    41521 aacgatagct aattggtgcg cccagtaccg ttgctgttgt ttcaaatgcc atgattttca
    41581 cctcgataaa attagtttct ctttattata aaagtttatc ctgattttta ctaggttttt
    41641 cagttaagtt ccctaaaaaa tgaaggcgtt ctctcagaca tctgttcata taagaatgac
    41701 ttcactagtt attttttgac agcacgaact aattgatcaa ggaaatactg gatgtcgtct
    41761 tcggtatttc ccaaaccaaa gctgatacgg atggattctt ttagtatcgg tgtatcttct
    41821 ccatacattg cttctaatac gtgtgaaggc tcgatatttc ctgctgtaca agctgaacca
    41881 gtagaaatag cgaccccatt aagatcaagc ttcatcagta gcaaatcatt tgcttcgcca
    41941 attaagcgaa gattcaacac atgagggagt ttattcgtta aatcaccatt tacttgataa
    42001 gggatttcgt ttgcttctaa tgtatcaaga atcaattgct ggaatccttt atatttgttg
    42061 ttacgtgctt cacgttcttc aggtgacagc agttcaactg cttttgccat accccagatc
    42121 cctgctaaat tttctgtacc tgcacgccgc ttttcttcct gctccccgcc taaaagcaat
    42181 gcagggatat ttactccgtc tcgtttatat aagaaaccga cgccttttgg cccattgatt
    42241 ttatgagcag agatacttaa taaatcgatt cctaattctt ctggatggat cgtttggttt
    42301 ccgtacgctt gtaccgcatc tgtatggaaa taagctggat gatccgctaa aagttcaccg
    42361 atttctttga ttggcatcaa atttccgatt tcattgttcc cgtacatcac agagaccaag
    42421 atcgtatctt ctcgtaacgc ttttttgacc tcttcgatcg acagattccc tttttcatct
    42481 acaggcagat atgtaacgtc aaaccccttt gtctctaaat atttcatggt attaagaaca
    42541 gcaggatgtt cgatagctgt agtgattaga tgtctgcctt ctttttgacg cgaaaacgct
    42601 gtttctaaga tagctgtatt atccccttct gttcccccac tgttaaagat gatctcgtga
    42661 ggttttgctt gcagactgtc tgcaatgatt tgtcttgctg tttccaattt ttcatgcgcg
    42721 tggcgaccaa atccatgtat gcttgaagga tttccaaacg tgtcttgcat gattgccgtc
    42781 atcgcttcaa ttacttgtgg atgcatgggg gtagttgccg catgatccag ataaatagtt
    42841 ttcacttcat tcatcccttc caaattattg ctaggcacat tctagcataa aatagcgaac
    42901 aaaccaaaga agagctcatt tttgtctaga ggacgtttca tgggcataga aaaaaggagc
    42961 tgtgacaaaa gtcttgtcgc agctccttga agctgctcac ttctgtcaca acttctttcc
    43021 ctcttttttt tgtttattcg aattcttttt cttccagacg gaataacgga ctcatcggtg
    43081 tattttcatg gatgcgtttg accgcttcac ccattaattc tgaacatgta acgattgtta
    43141 agttttctgg atgacgattt tcttctgtga aaacagaatc agtgatacaa atatctttga
    43201 ttggtgcatt gtctaaaata cttttcgcat gatcggacaa taatccatgt gacgcacagg
    43261 catatacttc ttttgcgccg ttttctttta atacatttgc tgctcgtgca agcgttgctc
    43321 ctgtgttcaa gatatcatct accatgatac atgtctttcc ttgaacatca ccgatcacat
    43381 aaccaccctc agttgaagca tcatctgcat gatctacgat ggctaatgtg ctgttcaaat
    43441 attctgaaag actacgtgca cgctgaacac cgctgttttt tggcgaaaca actacgatgt
    43501 catctcccgt cagacctaat tgacggtaat aatgagcaaa caacggcatc gtaaataaat
    43561 tatctacagg aatatcaaag aatccttgta cttgaaccgt gtgcagatct aaagtcagta
    43621 ctcgagttgc ccctgcttct tcgatcaagt tagcgatcaa tttcgcagtg atcggttcat
    43681 gaggtttcgc cgtgcggtct tgcctagcat acccatagta aggcaatacg acattgatcg
    43741 ttttcgcact tgctcgcttc attgcatcga tcatgatcag tagttccata tagtaatcat
    43801 tgacaggtgc attcgttgat tgaacgatat acacatgatc ccctcgaata ctttcttcga
    43861 tattgatgga aatctcgcca tcactaaatt gcttcacgac gcttttacct aattctgttc
    43921 cgaacacttt cgcgattttt tcagctaatg gacggttgcc attcaaacta aaaatcttca
    43981 acgtgtcatc ctgatactta ttactcatgt agtcctcccc aaaacttctc tattcttcga
    44041 tagtttaaca tatttttcca agattttctg ttaatttcag caaattctta aggaagtgaa
    44101 actgttccgt tactccaact ggcaggaatg actttatgat aatcgcccca gttgtcgtgt
    44161 actttgtaat aacgttctcc tgtttcagtt tcaaaataag cgtacgctgt cacccaatga
    44221 ttgccatatg tactgccaag tactttcaaa ataccaatca tcacaggttt gccttcacgt
    44281 atacgttttg tagctcgctg ccatgaacct agaagagttg ctcgtgcacg ctcatgattg
    44341 ccattcttct ttaaaaaact agaaatccct gtactaacct gaaaaggaat cgtaggaagt
    44401 cctagtggtt ggatctggct acgcaatgcc ttcgtcaaaa ccaacgaatc agccgtattt
    44461 ttcttgcgaa tctcatttgg aagcatccac cccttacgat agtcttgata ataggcaagg
    44521 agaactgctg ccgcgtaagt accacaaaga tagcctgagg gggtagccca tttcttatac
    44581 ctcaaaaaac gttcttctgg caatcccacc cagcaatttg cgagttcctt tcctgacctt
    44641 ttttcttcga tcaaaacggg aatatcttct tttctgttga tccatctaga taactcgatt
    44701 ggctcttcat tgatcagctt ccatttttta caagaaagac cctcttgata agtatatttt
    44761 gctggagaat attctaccgg atgtcctgat tgatcgataa tcacataact ttgatcttca
    44821 aaaaccagag ctaaaaaaag caatttactt tttcttgact gcagctgctg agtgctggct
    44881 aattttttaa tttttttatc tactttgaaa tataaaggtt tatccactac ttgattcagt
    44941 tgggatcgcc tccttttttt cattataagt gaaggattga aaaaaacaaa tcagtttgat
    45001 tgttcgaatt ttcaattttt tatgttctat ttgttaattc cttcattttg taagataatg
    45061 ggcacacgaa acaaaaaagg agcgatcgat gaatgaacaa agaacgattg aaacaagatt
    45121 tctatgaagc agtcaatgaa gaatggcaaa aaacagcaaa aatccctgca gataaaccag
    45181 ctacaggcgg tttccaagat ttagttgacg ggatcgacca acttttgatg ggagaaacag
    45241 acgatctgct tgcccatcca gaaaaagtgt cttcagaaaa aatgaaacat ttccttgcat
    45301 attatcaact ggcaaacgat tatgaccgaa gaaatgagtt gcatgctcaa ccgcttcaac
    45361 ctataatcga aaaagttgaa tcattgcagt ctttcgacga attgaataag caatttccag
    45421 aatggctgtt ggatacatta ccattgccat ttaatctgga tgtagatgca gatatgaaga
    45481 atgcgcaaac gaacgccttc tttgcttatc cgccttcttt attccttcca gataagacgt
    45541 attatgcatc agaccatccc aacggtgcac aactaatagg cgttttcttt gatatggctg
    45601 ttcagttatt agagcttgcc ggcaaagaaa aaagtcaggc agaagcaatc acggaacaag
    45661 cagtgcaatt tgataaattg attgctcctc atgtaaaaag tgcagaagaa aacgcagatt
    45721 acagcaaaat gtataatccg caatcttttg atacatttat taaatacaca gataaactgg
    45781 acttgaaaaa acttgtcacg ggtttgattg ggacaactcc agataaagtg atcgtaactg
    45841 atccagtgta cttcgatcat ttgaatgaca tcctgacaga agctcatttt ccgttattca
    45901 aaagctggat gatcattaaa acagtacgtt ctcttagtgg ttatctatca gaagaattcc
    45961 gccaagtcag cggaatctat tctcgcgtat tgtctggaac agacgaagca atgcctcaga
    46021 aaaaagcagc gtattacctt gcctctggac aattcgatca agtagttggc gattactacg
    46081 gaaaaaaata ttttggcgaa gctgctaaaa aagacgtaga acaaatggtg aaaaaaatga
    46141 tcgccgttta taaaaaacgt ctagaagaaa atgactggct tggggatgca acaaaagaaa
    46201 aagccgtcat aaaattaaat aacttaggta tccaagtagg ctaccccgat aagatcccag
    46261 cattattcga ccagttcaaa acagtacctg cagatcaggg tggtactttg ctttcaaata
    46321 ctcttgtttt cagcaaactc acattaaaag atcgtttcag caaatggaac aaaccagtgg
    46381 atcgttcaga atgggaaatg agtgctgaca cggtcaatgc ttattatcat ccatttcgga
    46441 atgtgatcgt ctttccggca gcgatccttc aagcaccatt ttacagtcta gaacaatcaa
    46501 gctctgctaa ttatggtgga atcggagctg ttatcgctca tgagatttcc catgcatttg
    46561 ataataacgg cgctttattt gacgaatatg gcaacttgaa caactggtgg acagaagaag
    46621 atcttacaca atttcaaaac aaagcacaag caatgatcga agaattcgat ggtctgcctt
    46681 ttgctgacgg aaaagtaaac ggaaaattaa ccgtttcgga aaatattgct gatgcaggcg
    46741 gtctaagctg tgcattggaa gcagcaaaaa cggaatcaga tctttctatc gaggaattct
    46801 ttgtcaattg ggcaacgatt tggcgtacaa aagcaaaaaa agaataccaa caacttttac
    46861 tgcaaatcga tgtccatgcc cctgctaaac tccgagcaaa cgtgcaacca aaaaaccttg
    46921 acgaattcta tgaaacattt ggtatcacgg aacaagacgc tatgtatcta gcgccagaaa
    46981 aaagagtgcg aatctggtaa gaggttgtgc cagaagtggt cagcttcaag aaataagaag
    47041 gaatttggga aaatcgcttc tcaaattttt gtgacatttc ggcttatttt tcgaagaagt
    47101 tacttctgga ataccatgta ttagaggttg tgaaaaagct gcttagtttc aagtagtaag
    47161 aaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttac taccgagaaa
    47221 ctggcttttg aacaccgttt atcgagaggt tgtgaaatca gcgtcctgac ctgagtatta
    47281 gagaaaaaaa cggaaaaata gttcctcata ttttgccgtt tgttgagcta ataccgaggg
    47341 tcagctgatt gaacaccgtt tagtggagag attgtgaaaa agctgtcctg catcaagtaa
    47401 taagaacagc caatcaaaag cagcaaggag aacctcatct ataaaaagat agaaggaagt
    47461 gagacatcta ttggtctcat ttccttctat ttttactttc ctcagtcaat tgttttacat
    47521 cataaaagga gaaattccac ttattttttt cgctgtttca tgacataaac aactacaccg
    47581 attaacaaaa ttcctccagc taatgctagc aacgggttat taaattctcc cgtttttggg
    47641 agtccttgag tgccattttt ttcactttct tttgctgtcc tatccggatg agaaggtttt
    47701 ccatttggtt ttccatttgg tgattcattt cctggatttt ctctttctgg tttgtcattt
    47761 cccgggggca catcggcagt ttctcgcaca gtgatcgctt tttgctgggt aacagattct
    47821 gtatgagcag accatttttc cccatcaaat atttccgaac gataagtgac ttctagcgta
    47881 tattctcctt ttgaaggtgc tgaaaaaata gcggtatgat tagaaaattg agcacttgac
    47941 tgtgtttcaa cgatttggat cttttctggg aaataacgca tatcttcaaa gacaggcgtt
    48001 ccttgatttg gtgtgaaagt tgacacaaaa actgtaaaag gcttcagttc aatgatattt
    48061 ccttctgcat tctccgccac accatttgct tcttgtataa taatcggatt attttgttca
    48121 tttggttttg tctgatttgg ttcttgtacg attgcatact ctggatattc cgaagacggt
    48181 gaggtttctc cgtcaaaaat agcacctaca gataatggaa gaccatccac tctttccttt
    48241 tctgtttgac gattccccgg tttaatctgc atcagtccat gaacatggat acttccattt
    48301 tcatagcgcg taacaggctg ctgaccttct ttcgaacatg tatttagaga ctcgatccaa
    48361 tcttttgata tggtatgtcc aagagtattt tctgattgtt tctctcgttc attccaatag
    48421 tagttcaacg agtggtagat ttgatcttcg ttttgattca atgggcggat ctgctctctc
    48481 atctcaagat tctctgttcg gaaagataag ataccagaag catggtagtc tgtgtttcct
    48541 gctgaagagg tataaagagc cacattatat gaaccgttat taaaacttgt actgctattg
    48601 acgataatat ctgttccgct attggaatcg attcctttcg caagattttc gaaagacaaa
    48661 ctattgatca attcatgagg gcccgttaaa gaagaaccgc ccattttgaa tccattaccg
    48721 ttaccttctc cctcaattcc tggtacccag ccgtttcgat aagcaactga gtttttgatg
    48781 attacttttc cgatcgaacc tgtttcattt ttagcaaaaa ggtcccaacc gtcatctgca
    48841 ttatgatacg cgatacaacc gtcaaataca tttccttctc ctattgtcag tttggccgca
    48901 aatccatcgg catcttcaaa tcctggatcg gcattttcaa aagatgtaca gttcttgact
    48961 aagttatgcg cgggccatgc ttcgaaagga tcatttgagc taccgctgat ttggattcct
    49021 gtatttccat tccgataagc atgaatctct tcgatcaaat tatgatttcc agaaatctgt
    49081 aatccttttt gcatagctgc actatttgta atgtcaaacc ctcgtaaacc ccagtagtga
    49141 ctgaacagtg tcatcccatt tccagttcct ttaaaatcaa gtacaggacg cttgttttct
    49201 ggatttttct ctgcaatcaa ctgaatcggg ttttctcttg tcccgttaac gccttttgga
    49261 atcgtcaatc ctctttcgaa ggaataagtt ccaggcgcca tgacgattgt ctgcccagca
    49321 tatgcgtatc tcaatgcttg tgtcagagat aatggatttt gtctgcttcc gtttcctgca
    49381 tctgaccctt ctggtgttac ataaactgtc gaatatttag gtttacggta gtccactgta
    49441 tgaagaatct cttttgtttc ataactagtc atctctacgt attcttctgg cggatagttt
    49501 ttatctggcg taaaactgaa agtaaattcg ttcgttcctt ccatcagttt tgtctgataa
    49561 tcaaattccc gattcgcagt gatagccaag ttttttgcgt tcttaagcac ctctcctgtt
    49621 gctttatttt taattgtcaa taatccgtca gcatttgctc taaaggacat agtatgatct
    49681 tggtttcctg aatgattact agaggtcaca gtgtaaatcg gatcaatcaa gcgagtaggt
    49741 ctttcttgcc caggaggatc tgtcgcagga tctgagtaag caacttcgat tccttctacc
    49801 ttgatcgtca tattccttgc tgcagcaaat cctgcataaa taaccgattc atctgaagcg
    49861 tataattttt cccagtcata catgatgtca gaagccattt cttctcctgt ttcaggatcg
    49921 taataatatg cctctaaacc agtattcgtt tttttcatct ctacgtccag tttagtaatc
    49981 gagttcgtgg ccggaaacag attcccatga ccgtttccga atatattata agaacctgtt
    50041 tctttttcca agaaccctgc tgaagtctct aaaggtgttg tttccactga gacactccca
    50101 ggagctggcg cagcttgcgg atcttcagat gatattcctg tgattgcccg tgtccccaat
    50161 ccaagtcgca tcgtatattt gctgccgctc gtgttgacca cttcttgtct atccgagtcc
    50221 cagacatatt cgatccgact gcctagtatg gcaaatgaat ttgaataaaa tgcctgccca
    50281 aacaaatgat tttttggtac tgcgtctctt ac
//
LOCUS       DASHXG010000013        49996 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.013, whole genome shotgun sequence.
ACCESSION   DASHXG010000013 DASHXG010000000
VERSION     DASHXG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.013"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1008)
                     /locus_tag="U2R59_000930"
     CDS             complement(<1..1008)
                     /locus_tag="U2R59_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8965341.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="U2R59_000931"
     CDS             complement(1188..1532)
                     /locus_tag="U2R59_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8965342.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="U2R59_000932"
     CDS             complement(1525..1959)
                     /locus_tag="U2R59_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEM8965343.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="U2R59_000933"
     CDS             2097..2834
                     /locus_tag="U2R59_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965344.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="U2R59_000934"
     CDS             2827..4038
                     /locus_tag="U2R59_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965345.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="U2R59_000935"
     CDS             4242..5024
                     /locus_tag="U2R59_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEM8965346.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="U2R59_000936"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="U2R59_000936"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEM8965347.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="U2R59_000937"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="U2R59_000937"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HEM8965348.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="U2R59_000938"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="U2R59_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEM8965349.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="U2R59_000939"
     CDS             8626..9675
                     /locus_tag="U2R59_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HEM8965350.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="U2R59_000940"
     CDS             9672..9950
                     /locus_tag="U2R59_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEM8965351.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="U2R59_000941"
     CDS             9925..10395
                     /locus_tag="U2R59_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEM8965352.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="U2R59_000942"
     CDS             10412..10714
                     /locus_tag="U2R59_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965353.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="U2R59_000943"
     CDS             10731..11102
                     /locus_tag="U2R59_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HEM8965354.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="U2R59_000944"
     CDS             11074..11433
                     /locus_tag="U2R59_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965355.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="U2R59_000945"
     CDS             11605..12612
                     /locus_tag="U2R59_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8965356.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="U2R59_000946"
     CDS             12637..13821
                     /locus_tag="U2R59_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEM8965357.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="U2R59_000947"
     CDS             complement(14258..15841)
                     /locus_tag="U2R59_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8965358.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="U2R59_000948"
     CDS             complement(16419..16562)
                     /locus_tag="U2R59_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEM8965359.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="U2R59_000949"
     CDS             complement(16785..17264)
                     /locus_tag="U2R59_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8965360.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="U2R59_000950"
     CDS             complement(17337..17621)
                     /locus_tag="U2R59_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965361.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="U2R59_000951"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="U2R59_000951"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="U2R59_000952"
     CDS             complement(17965..19251)
                     /locus_tag="U2R59_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEM8965362.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="U2R59_000953"
     CDS             19389..20060
                     /locus_tag="U2R59_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HEM8965363.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="U2R59_000954"
     CDS             20026..20514
                     /locus_tag="U2R59_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEM8965364.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="U2R59_000955"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="U2R59_000955"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEM8965365.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="U2R59_000956"
     CDS             21475..22239
                     /locus_tag="U2R59_000956"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEM8965366.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="U2R59_000957"
     CDS             22472..24685
                     /locus_tag="U2R59_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEM8965367.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="U2R59_000958"
     CDS             24696..25142
                     /locus_tag="U2R59_000958"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEM8965368.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="U2R59_000959"
     CDS             25313..26572
                     /locus_tag="U2R59_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HEM8965369.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="U2R59_000960"
     CDS             complement(26661..27608)
                     /locus_tag="U2R59_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8965370.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="U2R59_000961"
     CDS             28002..29294
                     /locus_tag="U2R59_000961"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEM8965371.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="U2R59_000962"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="U2R59_000962"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEM8965372.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="U2R59_000963"
     CDS             31187..32062
                     /locus_tag="U2R59_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8965373.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="U2R59_000964"
     CDS             32328..34211
                     /locus_tag="U2R59_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEM8965374.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="U2R59_000965"
     CDS             complement(34286..34570)
                     /locus_tag="U2R59_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEM8965375.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="U2R59_000966"
     CDS             complement(34560..35294)
                     /locus_tag="U2R59_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEM8965376.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="U2R59_000967"
     CDS             35423..36046
                     /locus_tag="U2R59_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEM8965377.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="U2R59_000968"
     CDS             36238..37359
                     /locus_tag="U2R59_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HEM8965378.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="U2R59_000969"
     CDS             37366..40494
                     /locus_tag="U2R59_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HEM8965379.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="U2R59_000970"
     CDS             40513..43707
                     /locus_tag="U2R59_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEM8965380.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="U2R59_000971"
     CDS             complement(43853..44560)
                     /locus_tag="U2R59_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEM8965381.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45325..45723
                     /gene="spxA"
                     /locus_tag="U2R59_000972"
     CDS             45325..45723
                     /gene="spxA"
                     /locus_tag="U2R59_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEM8965382.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            46055..46708
                     /locus_tag="U2R59_000973"
     CDS             46055..46708
                     /locus_tag="U2R59_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEM8965383.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            46934..47932
                     /locus_tag="U2R59_000974"
     CDS             46934..47932
                     /locus_tag="U2R59_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEM8965384.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            48108..49916
                     /gene="pepF"
                     /locus_tag="U2R59_000975"
     CDS             48108..49916
                     /gene="pepF"
                     /locus_tag="U2R59_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEM8965385.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        16175 a         8741 c        10455 g        14625 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaaagc gagaatgctg gttttactgt atattaacct
    45181 tagataactt tcattttttt aaaaaaatta tgaaaaaaag gtagctattt aaaagttgat
    45241 tatgtataat agaaacagat gggagattat tatgatcttc tgttacaaaa aagtgattct
    45301 tatcacgaaa aggagtggtg cacgttgtta acattatata cttccccaag ttgtacttcc
    45361 tgcagaaagg ctcgtgcgtg gttgcaagaa catcagattc catttgttga acgtaatatt
    45421 ttttcagaac cattgaacag ttctgaatta aaagcgattt tacaaatgac agaagacgga
    45481 acagaagaaa tcatctcgac acgttccaaa gtattccaaa aactgaacat ggatttagat
    45541 gatctgccgt tacaagaatt attggaactt gtgcaaaaca atcctggatt gcttcgccgt
    45601 ccaatcatga ttgatgataa acgtctgcaa gttggtttta atgaagatga aattcgtcgg
    45661 ttcctaccgc gcgatgtacg acaattagaa ttacgtcaag cacaattgat ggctggatta
    45721 tagaaggata atacgaaact tggaaaagac tattacaaag atagtttttc caagtttttt
    45781 tgtttttaca aaaagtattc ttgattagat gtataaaaag gtagtagaag atgatgattg
    45841 cacgaaaaat agagagggaa aattagctga aaagtcggct atatagtatt cgtctgccaa
    45901 aaatgttata gttaaataag atagcttgaa aggttgaaaa atccgctggt tttattaaat
    45961 tcgcttaaca gcgagatttt ttttctttac atttaagctg atttcgctac aatgaatcta
    46021 tattaaacat tgtggcaaag tgaggtgtag caaaatggaa atggaacata ttaatgaaaa
    46081 tacgatccgt gtactaattg gtcatgaaga tttagaggaa cggggcgttt catttttgga
    46141 tttacttggc aatcacaaag aaatcgaaaa tttcttttat agtattttgg aagaagttga
    46201 tatcgaagag gagttccgag gaagcgaagc tgtcactttc caagttttgc caaaaggaga
    46261 cggattagaa ctgtttatca gtaaaaatct tccggatgaa gaaatttctc aatcagaaga
    46321 ttctactgtt gattcagaag atgtgagtga ctttcttcgt cagcagatta ttggcagcga
    46381 tccggaggaa gaattatctg gaagcgccct agaagaacag gaaagacaag caacttttgc
    46441 ttttgaagat tttgaacaag tgatccaact tgcaacagat gtcgaactag agtctgcttg
    46501 gactgatttg tatttattcg aagagcgcta ttacctagtc gttcacttct ggatggaaaa
    46561 tctcaaccaa gcggatgtag agaatcagat tgctcgaatt ttggagtttg ctgaaaagag
    46621 cgatcgtaca ccagaaacat tgaatgaata tggacaatgt ctgatggcgc gtaatgctat
    46681 cgagcgaacg aaattttatt ttgtataaat cagcattata gtaagagact gtgacaaaaa
    46741 ttgtgtcgca gtcttttttt cgtataaatg tgttcaaaag cttgcatctg cggtaacaag
    46801 cccaaccaaa cgaaaaatat tgggaactat ttttgtttag ctgttcttat tacttgatgc
    46861 agaatagctt tttcacgccc tcttttttcg tgtaaataaa ttcttagacg taaataagtt
    46921 cagagggaga aaaatgctgc ttgcaatgaa tgaatataat aagtgctgtt ttgctaaaca
    46981 tgcagaaaaa ggaaagaaat attattgtcg tggctgtcga aaaagagtga ttttgaaaaa
    47041 gggaaagaaa aaatgtgctc attttgccca tcaaaaatca gataactgtt cggtctttag
    47101 tgaaagagaa tcaaaagagc acttacagtt aaaggaatgc ttcatggatt ggctgggaca
    47161 gtcagtagaa ccagtatttt tggaagccta tttgccgagg ttgcggcaaa ggccggatat
    47221 tttgttggcg aatctagcaa tagaaatcca atgttctaga ctgtctcacc agagatttat
    47281 tgaaagaacc caaaattatt tgaataacag ttaccaagta tggtggatac ttggtaattc
    47341 ttttcttgga caatcgcaat tctcattgat agaaaaaagt tgctgctact ataatagaaa
    47401 aagaggagtg cattgctgga aagctgatct caagaaacaa aagctttatt tgtatcatca
    47461 tattacagag actgtatcag ggcatatttc cttttgcagt agctgctgga ctttttctag
    47521 tagggacctt aaagaaatat tcactagtaa cgaaattaaa atgaaccaaa tgaaaaaaat
    47581 agaaaaagtg agtgaagatg ggaagaaatg gctgacacgc caacttattc acaagcaaaa
    47641 gaatacagta tccatacaag aacaatgcta cttgcgtcat aaacatcttt tgcatctatc
    47701 atcgtggatc tatcaaaaaa gtcggttttt cttttattta caagaacagg tttttcttta
    47761 tcgaatgttg tacgaagaag ccttggaaaa ccagaaagtt cctgatttca actcatggct
    47821 ttgccaaata aaagaacata aaagggaatg gctttttcct atgattgatg aagagatggt
    47881 ctatcagcag ttttttaacg aatgcataca cttgtcttct ttgaaaaaat agtaagtata
    47941 aaaataggct aggaatcggt tttctatgta aaacaagatt tagttatgct aaaattgatg
    48001 gaagcagaca catgaatgag tagaaaagtt agatgctgtg acatgtggat gttagactat
    48061 gatctatttt gatagataga gctaagggaa gaaaaggagt ggatttcatg gaagtaaagc
    48121 agttgccaaa acgagaagaa ttgcctgaaa atttaacttg ggacttgacc aagatctttt
    48181 caagcgacca agagtttgat gagaaatatt tggaattatc agaagagtta aaacaatctg
    48241 aaaaacacaa aggaacactt gatcaaggcg cttctcaatt tttaaatgcg attgaattcg
    48301 tattgagggt ttatcgccaa actgaagtca tttatgtata tgcgcacctt aaaaacgatc
    48361 aagacactgg aaatacagat taccaagcgc tttatgcaag agcaagcagt ctgttttcga
    48421 aagttagtga agccgtttcc tggtttgaac cagaaatatt gcaattgtca gatgaccaga
    48481 tttggcaata tttcaaagaa gaaccaaaat tggaagtcta tcgccattat atccagcaaa
    48541 tagtagataa tcgagcccat gtcttatctg ctgagcagga atctcttctt gctggagcag
    48601 gtgaaatctt tgatgcttca agtgatacat ttgctgtttt gaataatgca gatctagttt
    48661 ttccaacgat tgaaggagaa aatggtgaaa tagtccaatt atctcatggc gtgtatggtc
    48721 agttgctaga aagcacggat cgaagggtgc gcgaagcagc atttaagggg ttgtacagtg
    48781 tttacgaaca atttagaaat acatttgctt ctactttagg cacacatata aaaggacata
    48841 attttaaagc gaaagtccgt aattacagct ctgccagaga agcgtctttg agcaataatc
    48901 atattcctga aagtgtatac gatactttgg tagacgtggt aaacaagcat ttgcctttgt
    48961 tacatcgata catggaatta cggaaacgtt tattagaagt ggaaaaactg cacatgtatg
    49021 atctttatac accggtctta ggggaagctc caattacctt tacgtacgaa gaagcaaaag
    49081 aaaaagcttt agaagcactg aaaccaatgg gtgaagaata catggccatc gtagaaaaag
    49141 cattctctga acgttggatc gatgttgtcg aaaataaagg gaaacgaagc ggtgcttatt
    49201 cttcgggaag ctatgacaca aatccatata ttttattgaa ttggcatgat acgctggatc
    49261 agctatttac gcttgtccac gaaatgggac atagtgttca tagttatttc actcgttcga
    49321 accagcctta tgtgtacggc gactactcca tctttttagc agaaattgct tcgacaacga
    49381 atgaaaatat cctaacggag tatttattgg aaacagaaaa agaccctcgt gtacgggctt
    49441 atgtactcaa ccattacttg gatgggttta aaggaacagt tttccgccag acacaattcg
    49501 ctgaattcga gcatttcatg catacggaag atgaaaaagg tgtgccattg actagtgaat
    49561 acctaagtga tagttatggt aaattgaatg caaaatatta tggtccagca gtcgaagaag
    49621 acccagaaat taaattcgaa tggtcacgga taccgcattt ttattataat tactatgttt
    49681 tccaatactc gactggcttt tctgctgctt cagcactggc gaagaaaata ctaaaccagg
    49741 aaccagaggc actagagaac tacttggctt acctaaaagc aggtaacagc gattatcctg
    49801 tggaagtaat gaaaaaagca ggagttgata tgacacaggc tgcatatatt gaagatgcaa
    49861 tgtcgatgtt tgaacaacgt ctaaatgaat tagaagaatt gatcgatcgt ttataaggct
    49921 ttctattttt gattttctcg aatagaaacg aaaaaaatac gtcggctctc ttgtaaggga
    49981 gtcgacgtat tttttt
//
LOCUS       DASHXG010000014        49434 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.014, whole genome shotgun sequence.
ACCESSION   DASHXG010000014 DASHXG010000000
VERSION     DASHXG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.014"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(227..1114)
                     /locus_tag="U2R59_000976"
     CDS             complement(227..1114)
                     /locus_tag="U2R59_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965386.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="U2R59_000977"
     CDS             complement(1111..1980)
                     /locus_tag="U2R59_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965387.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="U2R59_000978"
     CDS             complement(2117..3403)
                     /locus_tag="U2R59_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8965388.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="U2R59_000979"
     CDS             3676..4254
                     /locus_tag="U2R59_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEM8965389.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="U2R59_000980"
     CDS             4254..5183
                     /locus_tag="U2R59_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965390.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="U2R59_000981"
     CDS             5180..6916
                     /locus_tag="U2R59_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEM8965391.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSLITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="U2R59_000982"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="U2R59_000982"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEM8965392.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="U2R59_000983"
     CDS             complement(7812..8321)
                     /locus_tag="U2R59_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEM8965393.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="U2R59_000984"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="U2R59_000984"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEM8965394.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGESHG"
     gene            complement(9622..10713)
                     /locus_tag="U2R59_000985"
     CDS             complement(9622..10713)
                     /locus_tag="U2R59_000985"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEM8965395.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="U2R59_000986"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="U2R59_000986"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEM8965396.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="U2R59_000987"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="U2R59_000987"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEM8965397.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="U2R59_000988"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="U2R59_000988"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEM8965398.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="U2R59_000989"
     CDS             complement(14676..15650)
                     /locus_tag="U2R59_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HEM8965399.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="U2R59_000990"
     CDS             complement(15631..17514)
                     /locus_tag="U2R59_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HEM8965400.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="U2R59_000991"
     CDS             complement(17532..19757)
                     /locus_tag="U2R59_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEM8965401.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="U2R59_000992"
     CDS             19872..20906
                     /locus_tag="U2R59_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965402.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="U2R59_000993"
     CDS             complement(20973..21986)
                     /locus_tag="U2R59_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8965403.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="U2R59_000994"
     CDS             complement(22064..22252)
                     /locus_tag="U2R59_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HEM8965404.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22676..22804)
                     /locus_tag="U2R59_000995"
     CDS             complement(22676..22804)
                     /locus_tag="U2R59_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEM8965405.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22807..24180)
                     /gene="rlmD"
                     /locus_tag="U2R59_000996"
     CDS             complement(22807..24180)
                     /gene="rlmD"
                     /locus_tag="U2R59_000996"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEM8965406.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24291..25346)
                     /locus_tag="U2R59_000997"
     CDS             complement(24291..25346)
                     /locus_tag="U2R59_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEM8965407.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25356..26786)
                     /gene="gatB"
                     /locus_tag="U2R59_000998"
     CDS             complement(25356..26786)
                     /gene="gatB"
                     /locus_tag="U2R59_000998"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEM8965408.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26783..28255)
                     /gene="gatA"
                     /locus_tag="U2R59_000999"
     CDS             complement(26783..28255)
                     /gene="gatA"
                     /locus_tag="U2R59_000999"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEM8965409.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28255..28560)
                     /gene="gatC"
                     /locus_tag="U2R59_001000"
     CDS             complement(28255..28560)
                     /gene="gatC"
                     /locus_tag="U2R59_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEM8965410.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28666..30702)
                     /gene="ligA"
                     /locus_tag="U2R59_001001"
     CDS             complement(28666..30702)
                     /gene="ligA"
                     /locus_tag="U2R59_001001"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEM8965411.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30719..32953)
                     /gene="pcrA"
                     /locus_tag="U2R59_001002"
     CDS             complement(30719..32953)
                     /gene="pcrA"
                     /locus_tag="U2R59_001002"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEM8965412.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33108..34667
                     /locus_tag="U2R59_001003"
     CDS             33108..34667
                     /locus_tag="U2R59_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEM8965413.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(34778..36709)
                     /locus_tag="U2R59_001004"
     CDS             complement(34778..36709)
                     /locus_tag="U2R59_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8965414.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(36727..37641)
                     /gene="pfkB"
                     /locus_tag="U2R59_001005"
     CDS             complement(36727..37641)
                     /gene="pfkB"
                     /locus_tag="U2R59_001005"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEM8965415.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(37638..38390)
                     /locus_tag="U2R59_001006"
     CDS             complement(37638..38390)
                     /locus_tag="U2R59_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8965416.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(38549..38758)
                     /locus_tag="U2R59_001007"
     CDS             complement(38549..38758)
                     /locus_tag="U2R59_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965417.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(38769..40097)
                     /locus_tag="U2R59_001008"
     CDS             complement(38769..40097)
                     /locus_tag="U2R59_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965418.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     NQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            40233..40388
                     /locus_tag="U2R59_001009"
     CDS             40233..40388
                     /locus_tag="U2R59_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965419.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(40462..41049)
                     /locus_tag="U2R59_001010"
     CDS             complement(40462..41049)
                     /locus_tag="U2R59_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEM8965420.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(41132..42382)
                     /gene="clpX"
                     /locus_tag="U2R59_001011"
     CDS             complement(41132..42382)
                     /gene="clpX"
                     /locus_tag="U2R59_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEM8965421.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(42629..43918)
                     /locus_tag="U2R59_001012"
     CDS             complement(42629..43918)
                     /locus_tag="U2R59_001012"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEM8965422.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(44072..45004)
                     /locus_tag="U2R59_001013"
                     /pseudo
     CDS             complement(44072..45004)
                     /locus_tag="U2R59_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(45161..45820)
                     /locus_tag="U2R59_001014"
     CDS             complement(45161..45820)
                     /locus_tag="U2R59_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEM8965423.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(45823..46848)
                     /gene="sppA"
                     /locus_tag="U2R59_001015"
     CDS             complement(45823..46848)
                     /gene="sppA"
                     /locus_tag="U2R59_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HEM8965424.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(46861..47151)
                     /locus_tag="U2R59_001016"
     CDS             complement(46861..47151)
                     /locus_tag="U2R59_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965425.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            47561..49366
                     /gene="glmS"
                     /locus_tag="U2R59_001017"
     CDS             47561..49366
                     /gene="glmS"
                     /locus_tag="U2R59_001017"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEM8965426.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
BASE COUNT        13698 a        10600 c         8878 g        16258 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttaattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagattctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgtacaacc catcagtcct tattgacaaa gagccactaa
    22621 aaagactaag aaacaataac aaaagttaac acttcttagt ctttctttag cacgtctatt
    22681 tattaaagat tttagggcct tttctcatgt ttttacgatc attcttaggt gtttccattt
    22741 gtttggatcg gcctccacct tgtttctttt tgatcaattc tttcattttt tctttttggt
    22801 ccatttttat tctcctttaa cgaatgaagc gactaattcg atatgatggg tttgcgggaa
    22861 aagatctaca ggctgaactt tcttcacggc ataacctgct tctgcaaata acttagcatc
    22921 tcttgcaaaa gttgccggat tacatgagat atagacgatt cgttctggtg acatttcgat
    22981 tgctgattca ataaaatgat gatctaatcc ttttcgtgga gggtcaacta cgatcacaga
    23041 tggtttgatc cctttttctt gccatttttt cataactttt tctgcttttc cgacttcata
    23101 atgaacattt tcgattttat tatttaaagc attgaactgt gcatcttcaa ttgcttctgg
    23161 aataacttcc atcccataca ccttatccac tctgtctgct aaagacaagc caatcgtacc
    23221 tattcctgaa taagcgtcga tcacaatgtc ttttttatct aactcggcaa actcgatggc
    23281 tgtttggtac agatactctg cttgttgagt atttacttga taaaatgact ttgctgagat
    23341 tcgataggtt tttcctaata gctgatcttc gatatagtct ctgccatata aaactttttc
    23401 tttgtctcct aaaatcacat ttgttttttc ttcattgata ttttggatga ccgaaaccac
    23461 ttctggcaat tcttcatgaa tagcttcagc aatttccttg gatttaaaga atttttcttt
    23521 acgagtaact aaaacgacca tcatttcatg ggaataatga ccacgacgga taatgatgtg
    23581 acgaagctgt ccttcatttt tttcttcatt atatcctcgt acttggaacc gttgcaagat
    23641 atctctgact actttgattg cttgatcgat gacaggatct tggatataaa aatcttcgat
    23701 agggactaga tcatggctat tctttttgta aaaaccggtg gctaactgtc catcgatacg
    23761 gcgaacaggg atctgtgctt tattacggta gccgaatggt tctgccattc cgaccgttgg
    23821 aagtacagga acttctggca tcttagcaat cttcgccatt acatgctcta cttgtttttg
    23881 tttgaagaca agctgttgtt catacttcaa atgggctaaa ggtgcgatac ctatgcgaag
    23941 taatgcattg ttttctacag gctgacgatc aggtgattgt gtaataaatg tttcgacttt
    24001 tccatatcca aacttattgc ctgcttttac tactagtatt tctacttctt ctccagggag
    24061 tgcattttcg ataaataatg gataaccatc gatttttgct acccccattc cttcataact
    24121 caagtcgacg atttcgactg tatatcgttc gtttttcttt actatttgct gttctgtcat
    24181 attttgctcc tttaagccta tttttcaatc ctactgaact ctactataaa tcagctaatt
    24241 acacaactaa aaccggcact gaccttacta cgttcagcac cggcttttga ttaattcttt
    24301 tgattaggtg tttcgtctgc tatttttccg tcaccgtcga tatcttcatc cgttaaacgt
    24361 tcgacttctt ttacgaattc tttgctgaca acctctaatt cttcttcatc tgtacctgtg
    24421 attgcttcat caggaatctg atcggtattg gcaaagaact caatgtgttg atgaagattt
    24481 tggaaatgca tcggtgcttc cccgccgtat tcaccatcta agttgatcat tactggtcga
    24541 ttgatatcat cttctgtttc aacgaacaaa ctgcttgttt tggtatagat tattcttgga
    24601 tcatcgacat gtcgaccgcc attcagcatg agtgctgcaa tatgcaagat ctcaaagata
    24661 tttgctgtct tcacaatgat taaagaaaac ttcccatcat ccaatttggc atctggcgcg
    24721 atctgttcga atcctccaac agagttcgtc agccctagga aaaacatcga agcatttccg
    24781 atatattccc cttcatcata cttcaagcgc attttgattg gctttactcg agggagcatc
    24841 tctgctcctt tcgcaagata agcaagataa ccaaaaatac tctttagttc tgatggaact
    24901 tcataagtca attctgtcaa atagccacct gcagcgatat tgatgaagta actgttatca
    24961 gaaaggccga tgtccatttt tacggtttgg tgttttttta tcacttctgc tgctgcttta
    25021 atattatctc taggaatttt taatgctcga gcatagtcgt tcgttgtacc agctgggatg
    25081 atggccattt taggacggtg ttcaagcgga gcgattccat taaccacttc gttgattgtg
    25141 ccatcgccac cagctgccac tactagatca aaacctagtt ctgcgactct acatgcttca
    25201 ttcttggctg aatctggttc tggtgtagtt gcataggcgc tggcttcaaa tcctgcttct
    25261 tctaatgcct gtaggatatc cgccaaattt tttttcaata attcttttcc cgaggtgggg
    25321 ttataaatta cgcgtgcttt tttcattttc agcctctatc gtttcgctaa ttcatcttta
    25381 agtagcttat tcacgacacc aggatttgct tgtcctttag ttgctttcat gatttgaccg
    25441 actaggaagc caaccgcacg atcttttcca tttttgaaat catcgacaga ttgttggttg
    25501 ttatccaaaa tttcattaat gattggcagt agtttgttcg gatcagataa ttgcacccaa
    25561 ccattttttt caactacttc ttgggcttct ccgccatttg tgatcaattc acggaagact
    25621 tttttggcga tttttgagct gatcgttcca tcggcgatca aacgaatcat tcctgctaag
    25681 ttctcaggtg tcaattttgt ctcagctaat tccagtttct cactgttcaa gtaagcagaa
    25741 acttcaccca tcaaccagtt agatgcctgc ttggcatctg caccattttc caaaacagct
    25801 tcaaaaaaat cagacatttc ttttgtaagt gtcaatacca ttgcgtcata ctctggaagt
    25861 ccaaactcac ggatatagcg ttcgcgacga gaagctggca tctcaggcaa actagctttt
    25921 actttttgaa tccattcgtc atcgatcacg aatttcggga tatcaggctc tgggaagtaa
    25981 cgataatcac tagacccttc tttgacacgc atcaaaactg ttttattcgt tgtttcgtca
    26041 aaacggcgtg tttcttgttg gatttctcct cctgaaagaa gaacttttgc ttgacgtttt
    26101 tcttcaaaag ctaaaccttt tttcacgaaa gataaagagt tcaagttttt caattctgct
    26161 ttcgtaccga actcttcttg tccataaggg cgaagagaaa tattggcatc acagcgcata
    26221 gagccttctt ccattttcac atcgctgact tctgtaaatt ggataattga tcgcaatgct
    26281 tctagataag cgtatgcttc ttctggtgaa cgcatatcag cttcagaaac gatttcgatc
    26341 aaaggcgtgc cttgtcggtt caaatcaacg taagaataac cgccaatacc atgcatgttt
    26401 tttccagcat cttcttctaa atggacacgt tcgatccgga tttttttctt tttaccttct
    26461 acttcgattt cgatccatcc gtcatgaccg attggttgat caaattggga aatttgatat
    26521 gcttttggat tatctgggta aaagtaattt ttccggtcaa aatgagtatc tttagagatt
    26581 tcacagttta atgccaaagc tgctttcatc ccgaattcca gcgcagcttt attcattact
    26641 ggcagcacgc ctggataacc ccagtcgatc acgtttgtat tgctgtttgg ttctgcacca
    26701 aaatgagctg gcgctggaga gaaaattttt gagttggttt ttaactcgac gtggacttct
    26761 agtccaatga ctgtttcaaa attcattcgt ctttccctcc taaaatagct ggttgttgtt
    26821 tatggaattc tgttgcttgt tcaaacgcat atgccgcttg atacatcgtt ttttcatcaa
    26881 aataattacc gatgatctgc aatccaactg gtaatccttc tgataaacct gccggtacag
    26941 acatacctgg aagtccagcc aagttgacag ggatcgttaa gatgtcactc atgtacattg
    27001 tgattggatc gttaatgttc tcaccgattc cgaatgcaac tgttggtgaa gatggcccga
    27061 tgatcaagtc ataatctgca aagacttttt caaaatctcg tttgatcaat gtacggactt
    27121 gtcccgcttt tttgaagtaa gcgtcataat aaccagcact taaggagaat gtacctaaca
    27181 tgatacggcg ttttacttct tcaccgaatc cttctgaacg tgagttgaca tatacatcat
    27241 ctaatgattt cacattttct gagcgataac cgtagcggat accatcgaat cgttgcaagt
    27301 tggaacttgc ttctgatgag gcaatgatat aataaacagc cacaccgtat tttgaatgag
    27361 gcaagctgac ttcttccaca acagcaccta atgaacggaa tgtttctgct gctttcaata
    27421 cagcttcttt tacgccaggg gccacacctt cgcctaagta ttctttaggt aaagcaatct
    27481 tcattccttt gatgtcgcct gtcagtccct ctgcaaaatc aggaactgaa acgcctgaag
    27541 aagtaccgtc tttttcgtca taaccgctga tagctgtcaa tgctaatgca ttatctttca
    27601 ccgtacgggt cattggtccg atttggtcaa gagatgaagc aaaggcaatc aaaccaaaac
    27661 gtgagacacg gccataagta ggtttcatcc ctacgatgcc gttaaaagct gctggttggc
    27721 ggatacttcc cccagtatca ctacctaaag aaactggaat ttgtccagct gcaactgctg
    27781 ctgcagaacc accagaagag ccaccaggta cttttgttgg gtcccaagca ttttttgttt
    27841 tcttgaaata agaagtttct gtacttccac ccatagcaaa ttcatccatg tttagcttac
    27901 caacagggat catatctgct tgatagattt tatccatgac cgttgcatca taaattggtt
    27961 caaaattgta aaggatctta gatgcagcgg ttgtcaagat atcttttgtt acgatattat
    28021 ccttgatacc aattggaata ccagcaagga cgttgctttc atcaatccct ttttcatcta
    28081 aagcttttgc ctgttccaat gctttttctt cgttcaatgt aatgaatgct tcgacctcag
    28141 gctctgtttc tttgattcgt tcaaatgttg cttttgtcaa atcttgtaca gtgatttctt
    28201 tcgatacaag catatgatgc agttcttcta gagaacgatt gtgtaattct gtcattatgc
    28261 gccagcctcc ccattatcga tgattgcggg tactttgata aagccgtctt ctgtttccgg
    28321 cacatttttc aataattcat cgcggttcca tccagcttgc gcccgatctt gtcgcatcac
    28381 gtttactgtt tcaaccacat tcgacgtaaa tggaacacct tctgtatcta cttcttccag
    28441 catttcaacc atatcgatga ttttacctaa ttggtcggta aaacttgcaa gttcttcatc
    28501 tgcgaacgca agttttgcta atttggcaac gtgtttcact tgttcttcac taatcgccat
    28561 actacccctt ctttctaaac gagttaaaaa ctttgctctc tattttaaca caagagtgcc
    28621 gtgtctgaaa ttgtttattg aaatttgtct gaaaaaactc atttttcatt cttctactga
    28681 gcgactttta gccaatgcat ctgccatttg atcttctgtc caaacttcga ttcctaattc
    28741 ttgtgctttg gtcagcttgc tgccagcatc ttctcctgct accacgatat ccgttttttt
    28801 cgatacgcta ccagtcactt tcccgccaag attttcgatc gtctcttttg cttcttcacg
    28861 agtaaatcgt gttagtttac cagtaaggac tactgttttt tctttaaaag gagactcgac
    28921 ttcttgcaat tgggcatttc gaagcccttt gtattcgaaa ttgacgcctg cttgttttaa
    28981 ttcattcatc aattcatgga cttcttcgtt actgaaataa gtgactacac tgtcggcaat
    29041 gatatcaccg atcgtatcaa gcgcaataat cgactcatag tcacttttac tcaatgtttc
    29101 tagatcaccg aaatgttctg ctaaaatttt tgctgctttc gctccgacat gtcggattcc
    29161 taacccgaaa atcaaccgct cgaccgaatt atctttgctg ttgtcgattg ctgtcaaaat
    29221 attatttgct gatttttctt ttattttgtc caacgtcaat aactcttctt ctgtcaattt
    29281 gtaaagatca gcaacatctg ctactagttt tttatcatac atctgttcta gtacgcgcgg
    29341 ccccaaccca tcgatattca tcgcatttct tgaaacaaag tggttcaaac cttctttcat
    29401 ttgagcaggg catttaggat tgatgcaccg taaggctact tcttcatcca aatggacaag
    29461 ttcacttcca caaactggac aatgtgtagg caattggtat tcttcgctgt ctttaggtcg
    29521 tttatctaac acgacttgcg aaacttctgg gatgatgtct cccgctttat aaatcagaac
    29581 tgtatctttc aagcggatat ccttcaactt aatataatca ccgttatgca ggctggcacg
    29641 gcttactgtc gttcctgcta ctcggactgg tgtcatgata gctgttggcg ttactacccc
    29701 tgttcgaccg actgtccatt cgatgttttc gattagcgtt tcaacttctt ctggcggaaa
    29761 cttgtaagct gctgcccatc tcggtgcttt gacagtaaaa ccaagttgat cttgtagcga
    29821 gaattcattc actttgatga cgattccatc gatttcatag ggcaaatcca cacgtttgtc
    29881 atgatattct tcaatgtatg accacacttc atcaatcgaa tgacatagac gtttttcccg
    29941 attcgtgtgg aatccaattt tttctagctc ttctagcgca tcatactggg tttttgcttg
    30001 cataggaccg aaatcagcta ctgtgtataa aaaagtgtcc agatttcttt tcgctgtgat
    30061 tttagaatct aactgacgca aagaaccagc tgcggcgttc cgaggattcg caaagatatc
    30121 ttttccctct gcttctctgt cttggttcaa ttggacaaat gaccgttttg gcatgaaaca
    30181 ttcgcctctt acttcgatgt tcattggttc ttttaatttg attgggaccg accggacagt
    30241 ttttaggttt tcagtgatgt tttctcctac agttccatcc ccgcgagtcg cacctctcac
    30301 gaaatttcca tcttcataac gcaaagaaac ggaaagtcca tctattttta gttcacagca
    30361 atagtcaact acacgtccca ctgctttttg tacacgttga tcaaaagcta tcagctcttc
    30421 tttgctgaaa acgtcgttca aactgtaaag cggaatatca tgagtgactt tttcaaaacc
    30481 ttctaatact tttccgccta ctcgttgagt gggagaatca gacgtgatca aatcaggata
    30541 ttgttcctca attgctacta attctgcgta ttctttatca taaacatagt cttccactgt
    30601 tggtttatct tctacgtagt attcgcgaga ccattggttc agtcttgtac gaagttcttc
    30661 tgctcgttta gcagcttcgt caatcgtcat ttcatgttcc atcatttacc ctccactact
    30721 aagctttttc aattggcgca aaggcagcca aaagacgttt tactccttga cttgggaaag
    30781 ccacatctag ttctagatcc ttcgacgtcc cgcttactcg gacgactgtt cctagacccc
    30841 attttttgtg tttgacttta tctccaggtt tccagctgtt attttcccct ccagtagcac
    30901 ttttagaggg aacaaccgct gtctctggct gtttatagct atatgctgtt tttttagcga
    30961 atacaggtgt ttttttaggc gtaggacgca tgccttcgat ttccagtaac tcctgatcga
    31021 tttcttctac aaaacgagaa ggtcggttat attgcgtccg tccatataat gttctggaga
    31081 aagcatttgt taaatacaac gcttcttctg ctcgcgtgat ccccacatat gcgagacggc
    31141 gttcttcttc cagttcgctt tcttccatca atgctcgaga taaaggaaaa accccctctt
    31201 ctagaccaat caggaataca actgggaatt ctaatccttt ggctgcatgc aaagtcatca
    31261 atgtcacttg ggaagcatct tcttctaaat tgtcaatatc ggaaacaagt gccagatcat
    31321 ttaagaagac cgttagtttt tcttctggtg catcagcgtc ttcttcattt tgctgttcga
    31381 attgtttgtc gaattcttgt gtgaccgtta aaaattcctc caagttttcg atgcgtgctt
    31441 gtgcttctaa tgtattttgg atttttaagt cttctagata tccgctacga tccaaaacct
    31501 ctttcgtcaa ttctgtcact gtcaagtatg ggatcatctg agtgacttct tggatcatct
    31561 ctccaaatgc acctaattgc tgtcctgctt ttccaccgat atttgccaga tccacatttt
    31621 gcgctgcttc aagcagtggc cattcatgaa gagaagcaaa actgcgtagt ttttcgatag
    31681 atcctggtcc gatgcctcgt ttgggcgaat taacgatacg ctcaaaactg attgaatctt
    31741 gaggatttgc cagcacattc aaatacgcta aaatatcttt gatttcttta cgatcgtaga
    31801 acttgtgccc tccaaccatt ttataaggaa tatttgcttt caacagagtt tcttccatta
    31861 cacgagattg tgcgttcgtc cggtacaaga tggcaaagtc gccgtaattc cgatgattgc
    31921 ttcgaatctc ttcttgcatc cgatctacga taaaacgggt ttcgtctcgt tcattatctg
    31981 cacggtagta agtgatcttg tttccttctt tgttttctgt ccacaagttt tttggttttc
    32041 gattgctatt gttttcaatg acttggtttg ctgcgctaag gatgtttttc gtggagcgat
    32101 agttttgttc tagcaaaatt actgcagcat ctggataatc tttttcaaaa tccaagatgt
    32161 tctgcatatc tgcaccgcgc cagccgtaaa tactttgatc tgcatctccc acgacgcaca
    32221 ggttcctaaa tctacctgcc aataaattga ctagcgtata ctgtgcgtga tttgtatctt
    32281 ggtactcatc tacatgaata taatggaatt tgttttgata atatgtgagt gaatcaggat
    32341 gttcttcaaa taatcgaatc gtattcatga tcaggtcgtc aaagtccata cattgattat
    32401 attgaagctc tttttggtaa gcagcataac attttgccgc aatctcttcg taataactgc
    32461 cttgcatttt tgcaaaatcc tgaggggtct gcaggctgtt ttttgcttga gagattgttc
    32521 ctaatatact tcgaggatca tattttttcg gatcaatgtt cagttctttt agtatccgtt
    32581 tcatcaaggt cagctgttca gaagaatcga tgattgtaaa gttccggtta tacccgataa
    32641 aatcaacatc tcttcttaaa atacgcacac acatcgagtg aaaagtcgat acccagacat
    32701 cttcgcctcc agatgcgaga atcgcattga cacgttcttt catttctttt gcagccttat
    32761 tggtaaaagt aatcgctagg atgttccaag gattgacttc tttttcctca atcaaatagg
    32821 caatgcggtg tgtcagcact ctcgtctttc cacttcctgc acctgccatt agcagtaatg
    32881 gtccgtcagt gtgaagaaca gcttctttct gacgggggtt catcccgttt aataattcag
    32941 ctttggatga cattaacaac atcctttctt ttatcaatct tgttaattat agcattttct
    33001 tggctttcat taaactagct agttcaaaat catttgtttc tttttatgga tttttccttg
    33061 tcaattcgtt gatttcgcgc taaattaaaa gaaagcgagg cgtttgaatg gaaaaaaaag
    33121 gaaaaatcaa gaaattagat aagactcaga tatattttat tctaaaagga atatttgttg
    33181 gactgctgac aggaatcgtc gttagcctgt ttcgattatc tatcgaaaag ctaagcgatt
    33241 tagttcgaag tatctatgaa atgagtcggg aacagccgat ttacttaatt ggcctagcta
    33301 tttgctgcat ccttgcagca tttttcgtgg gttatctggt caaaaatgaa ccggatatca
    33361 agggaagcgg gattccacaa gtagagggac agcttcgcgg ggaattatca atgaactggt
    33421 tctctgtttt atggaaaaag ttcattggcg gtgtactttc agttggtgcg ggcctttttc
    33481 taggtagaga aggaccttct atacagcttg gcgcatccat tggacaagga gctggacaat
    33541 tgtttcggag tccatcttca gaagaaaaga ttttaatttc tagcggtgca agtagcggac
    33601 ttgcagcagc attcaatgct cctatcgcag gattactctt tgttttagaa gaaatccatc
    33661 actccttttc tccacttgtt tggctgacat catttgcttc agcaatcact gctaacttcg
    33721 tctctcttta ctttttcggc ttgagacctg ttttatatct aggtgacctt ccttctttgc
    33781 cgttgaaata ttatggttcc ttagtgatct taggagtact tctaggcatc ttaggtttta
    33841 tttatcagaa ggtcttgctg gctttgccaa aattttacaa ccgattgcct ttaccagctt
    33901 attttcacgg gttcgttcct ttcttgctga ttttgccaat tggttattta tggcctagta
    33961 ctctaggcgg aggcaatcaa atcgttttag cttttggaca tgcttccttg ccaatcatta
    34021 tgattatcgg tttgtttgtt cttcgattcg ttttttccat gatttcttac ggtggtggtc
    34081 ttccaggggg gattttcctt ccgatattga cattgggggc tttaatcggt agcttttatg
    34141 gaaacattat ggttgatttc gggatggatc caatctacat caaggatttt gtcgttattg
    34201 ccatggctgg ttatttcaca gcgattggaa aagcaccgct gacagcaatt attttagtga
    34261 cagaaatggt tggctctctt aatcatctga tgcctttagg attggctgct cttgttgctt
    34321 atatcgtcaa tgaccttctc ggcggtaatc caatttacga atcattattg gaacgtctac
    34381 ttggaaatac tcagaccgcc tcactaaaag gtgcaaggac aacttttgat tttccagtaa
    34441 cggcagagag ttctttagac ggattaatgg tacgagactt caattggcct aaaaatatgc
    34501 tgctaatctc tatacgcaga ggaaatcagg aaatcttgac tcacggtgat acgatcatga
    34561 atgtaggaga tattttggtt atcttgactg atgaagcaaa cttgccaaga atcaagcagg
    34621 aaatcgaggc taaatcttct atcacaaatt tgaagcaatc attttaacga acatggaaaa
    34681 actattttac aacaactatt catctacact acttgattct atatgattct ataaaaaaag
    34741 aagagactgg gaaaaaccag cctcttcttt tttatttcta tgcttctgct gctgcaggag
    34801 cttttctcaa taaaccataa atcacaccag atacgactgc tccgatagca ataaacacca
    34861 aatacatgac cgggtgactc agtaagaata caacgaaaat cccgccatga ggagccagta
    34921 atttgatccc gaaagctccg actaatccgc cagttaaagc agaaccaata ataaaacttg
    34981 gaatggcacg aatcgggtca gctgctgcaa atggaatcga tccttccgtg acaaacgata
    35041 gtcccatcac gatgttcgtc aaaccagcat cttgatctgt tttgctgaat ttattcttaa
    35101 acaaacgtgt agcaacgaaa attgccaatg gaggtaccat tcctccagcc ataacagaag
    35161 ccatcacgac acttccgcca gttgcaacag tcgtagctaa agttgctgta ccaaacacat
    35221 aagcggcttt gttgattgga ccgcctaaat ctgccgccat cattccagct aataatgcac
    35281 caagtaaagc agcattcgaa ccactcatac ttgtcaagaa accgttcaat gcatcattga
    35341 ttgctttcat agggacattg accagcaaca tcaagaaacc agtaatcagt aagccaaaca
    35401 ctggataaaa gaggatcgtt ttaattccat ccaatgattt tggtaagttc ttgaataatt
    35461 tacgtaaaaa tacgatgaca taaccagcta agaatccacc aatcagtgca cctaagaatc
    35521 ctgcaccgcc tgtattagct aatgcaccag cagcaaatcc aacgatcaaa ccagggcggt
    35581 caccgatact tgaagcaata aatcctgcta ataccggcag catgaaacca aatgcagctt
    35641 gtccgatttg gttgaaccag ctagcagctt gattgtaatt ccctagattt gataattgat
    35701 catgtggcac gccaataaat tggtcgatca tgaaagaaag cgcaatagcg attcctccac
    35761 caataacgaa aggtaacatg tgtgatacgc cgttcatcaa atctttgtaa attctttgtc
    35821 cgatagtacc atccgcattt ccttcttctg aactgctttc ttttccatca ccatggaata
    35881 ctggtgcagt accactaagg gctagattga tcagctcttc tggtttacgg ataccatcac
    35941 tgacaggacg attgatcagt tcttttccgt caaagcgatt catctctact tttttgtctg
    36001 ctgcaacgat tacaccttct gcacgggcga tgtcttcagc agtcaatcgg tttttgattc
    36061 cttctgaacc gttcgtttcg actttgatct ccacacccat ttctttcgct tttttcttca
    36121 gagcatcttc tgccatgtaa gtgtgagcga tccctgttgg acaagctgta acggcaacaa
    36181 cgaattttct ttctggatga gcagaagctt ctgcagcttg tgtttcttgt tctgcttttt
    36241 cttctgcttc tttttgctct tcagctgttt ggaacaagtc ttggacttct tctggtgtat
    36301 ttgcttcttt taattttcct acgaaatctg catcaatcag caatcgagat agtgctgcta
    36361 atgcttgcaa atgtgtgtcg tttgcgcctt ctggagctgc gatcatgaaa aacagataag
    36421 ttggctgtcc gtctaaggct tcataatcta ctcctttttg gctttttgcg aataaaactg
    36481 ttgcttcttt aactgcactg tttttcgcgt gaggcatggc gattccatca ccaagacctg
    36541 tagaagtttg tgcttcgcgg gctagaattc cttctttata tgtttcgata tcggaaatcc
    36601 ggccggcatc aaacattttt tggaccattt catcgattgc gcctttttta tcagtcgctt
    36661 gcaaatccat gatcatcgct tctttgacca ttaaatcctt gatattcatg attatcctcc
    36721 ttgaaactaa tcaatttttg tgatttcaac ttctggcagc aactcatcaa tcaattcgcg
    36781 agctgccaag tcatcagaaa aagctgttgc gcttccgcaa gcaactcccc atttaaaggc
    36841 ttcgattgga tctttcgtac ggctgtaagc cccaataaag ccggcaatca ttgaatcccc
    36901 tgcacctact gaatttttca atgggcgaac taatacattc gttttataag ttccttgttc
    36961 cgtgaagagc aaagcaccgt ctccagccat tgagatcagc acattctgtg ccccttcagc
    37021 tagcaatttt ttaccatacg gaatgatttc ttctacagat tggaaggttg tattgtaaag
    37081 ctcagctaat tcgtgattgt ttggtttgat caacaatggt ttcttaacaa gtgcattttt
    37141 taggtcatca cctgttgtat caatcacgaa atctgcacct ttttctcgaa tgatatcaat
    37201 cagttcttga taaaatcctt ttcgcaggct agccggcgcg cttcctgaca atacgacgat
    37261 atctccttgt cctactgttc ctaatgcttg cttcaactca tcgatttctt catctgaaat
    37321 agatgggccc aaaccgttaa tttcagtttc agtatctgat tttagtttga tattgattct
    37381 tgtatcttct tttacggttg tgaacaaaga ctggatttgt tctttttcaa gccacttcga
    37441 aataaattcg ccagtgaacc ctcctaaaaa ccctagtgct gtagattgag aatcgatccg
    37501 tttcaaaata cgggaaacat tgatcccttt tcctccaggt aacttgaagt cttccttcat
    37561 tcggttcaaa tcgcctagtt ttaacccatc tacgcgtacg atataatcaa ttgatggatt
    37621 aagtgttact gtgtaaatca ttgtattgcc tccttaattg ttgtcttttc acggaattca
    37681 ttaacgaatt ctaatggaca acgctcggtt atgatcgtgg ctgcttccaa aggtgcaaca
    37741 gaggtgaagg acaactggtt gaatttggta tgatcaatca atacaaatgt ctcttcggaa
    37801 tttttcatgg ctaaacgttt aacagctgcc tcttctgggt ccggagtcgt gaatccttgt
    37861 tcaagatggg caccgttcat tcccataaat gctttattaa aatgaaaatt ttttagttgt
    37921 tctatcgcat tagatcctaa aacagcatta gttgccagct ttatcgttcc acctaaaata
    37981 atggtagcaa gctccaaatc aactaaattt gccgcatgtt gaacggaatt tgtcactact
    38041 gtgatctgtt ttccttgcag aaaaggaatc atttctaacg tagtagagcc agcgtctaaa
    38101 taaatgacat cttcgtcatt aatggtttca gctgccgatt tggcgatttg ctgtttttcg
    38161 tgaacgtttt tgagtgattt ttcactcata ttctgctcaa aattcaataa ttgctctttc
    38221 ttagctccgc catgaactct ttctagaaac ccactattct ccagctcttg taaatcacgt
    38281 cttatcgttg attcagaagc attaaaaagg tttacaagat cttgtgattt cacgattttc
    38341 tgctgttcaa gcaagtctag gattttttgt ctacgttcct ctgtaagcat tttcacgatc
    38401 acctcaatac aaataatagc atattttttt tctactcgca atataaatca gtcaaaaacg
    38461 ttcataaaaa ttataaatca gtcaaaaaaa aataaaaaac cagtcaaaaa gactggtttt
    38521 ttattttttt gtctatcatc aagccgtttt atcgtttttt attttcgctt cttgtttttt
    38581 tcatataaac agaagcaggt tttctttcct tatgaagaag ataataataa agtcccatcc
    38641 cgccaaacat gaccaaaaaa ccgatgactg atcgaatagg aaaattagga acaaaaaaga
    38701 gacagacgga taataatgat gccggaacca ttattcgata atagagttgt ttatccattt
    38761 tcttcacctc atattttttg taaagtaatc aattgttcta attctcggta atctaaaaat
    38821 tgcacacgca gatgctgctc acctttcttg acatcgaatt ggatacttcg ccgctttttc
    38881 tttattcgtt tgaaggtaac atcagagagt ctatgtttga tttcctttaa cggtaattct
    38941 gacagggatt ctgaaggaac atagattctt aaggataaaa gatactcttg atatttttca
    39001 tctgttacct ctacttctag atattcccta atataataac aataagcttc gattccatta
    39061 tccaaagcaa cagtcggatc gataacttta tagcacatca tgcgcgagcg attctcgtca
    39121 acccaaggaa aatacgcctg agcatttagt gttccgcgaa cacgcctttc tttataatct
    39181 ccttgttgaa tatcataact ttttgttaca aaaaatgaag cattcttttt aggaacaggt
    39241 tgcatttgtg cattctgata ctggacagat tggatcgtat ggtcagtgta aatgtattca
    39301 acgaatggcg gtttcaataa accgacacca ttgtcccaag caagatgatc aaacccaagc
    39361 tggtccctaa aataggattg aaacatttga ttgtttggct tttgccagtt aaaggggtct
    39421 cgataaagct ggatacatat gacttcgttt tctaattcct tcactttttc tacttgttgg
    39481 atgtcgagaa aaatcggttt agggatgatt tgatgataat agcgactata atacatttcc
    39541 caacacgaag tgaaacataa accttggtaa aaaagatcgt atcctggaaa ttggttgcaa
    39601 tcgactacta cttccccgtt ttgttgtttc attttaggta aatgttcgat ttcatccttt
    39661 ttctcaaaca atagccgttg agagatctgt tttgtattgt gatagataaa ctcgctataa
    39721 gctcgcatat aggcgaacac cccatgagca atcatttttt tctgaatgaa gtctcgaatc
    39781 aaaaattgat tttctttgaa aacagagata gacaatacat tttttatcaa taattgatta
    39841 tcttccaagc gaaaactaca ttcgttctcg tcatttccta caactaacca actttcgtct
    39901 cttaccgatg ctagcattat tttttcttga agctttcgaa gatcatacgg atccgcttgt
    39961 tgtgtgaaag agcggataaa tgttggctgg atcaacagac gtgtcaaaat agcccaatcg
    40021 cttatttcct gttttttttc ttcttcattt aagtctgtga gctggatagt catcaataat
    40081 ttatcttcgc caatcatttt ctcacctctt taaaatcttt ttataattta attataacca
    40141 acgataaaga aaaactaaaa ctttatgtct tagaaaccaa tttggacgat tacatgatag
    40201 actaagtaaa aagaaacaaa gaggtgttta caatggggtt gaaatttgaa cgtacagata
    40261 atttagataa acttttcgaa tcatttgctg tcgatccgga aaaaacagtt gcaccaaaag
    40321 aagagatcga tcgatttcta aaaccacagc cacaaaatga aaagaaaaaa gacaagaaac
    40381 aaaagtaagt taagctcaaa aaaagactta ccagccaaac ttttatgaaa gagtttgact
    40441 ggtaagtctt ttttattctt tttatgattc aattgcttgt tcgattgctg cccacgcttc
    40501 ttcttttccc tgttttgtaa cggaagaaaa gagaataaac gtgtcattgc gatcaaaatc
    40561 caacgctttt ttgatttcgc tctcatgctt gttccattta ccacgaggga tcttatctgc
    40621 cttagtggca acaacaatta cagggatatc ataatacttc aaaaattgat acatctggat
    40681 atcttcttga gaaggcttat gacgcaaatc tactaaagaa acgaccgcac gtagctggtc
    40741 tctagtcgtt aaatatgtct cgatcatctt tccccatttt gctcgctcag ttttggatac
    40801 ttttgcatac ccatatcccg gaacatcgac aaaatgtaat gcgttctcga tcaaataaaa
    40861 attcaatgtc tgggtctttc ctggcttacc ggaagtacgg gctaaattct ttcgatcaat
    40921 caatgtgttg ataaaagaag atttccctac atttgatcgt cctgccagag ctatttctgg
    40981 caattgtgta tctggatatt gttttggtgc cactgcactt atgataattt cagcttgatg
    41041 gactttcatg gtctctctcc ttaacaaggt gatgaataaa gcaagcggct gtcgcaaaag
    41101 ccaaaatgac ttttacggca gcctcttttc atcaacccgc ttttttctct gaatctttat
    41161 agattactgt tggctcacca gacaattcag ctgcttcttt tgtgataatc actttttcga
    41221 tgttttcatt tgaagggata tcaaacatca catccatcat gatttcttca atgatggaac
    41281 gaagtcctcg agcaccggta ttgcgttcga ttgctttttt cgcaatggct ctcaacgctt
    41341 caggttcgaa ttcaagttcg gtattatcta gagaaagaag tttttgatat tgtttgacta
    41401 gcgcattttt cggctcagtc aagatccgta ccagatcatc tgttgtcaat ttctctaaag
    41461 ctgccataac aggtaatcgt ccgataaact cagggatcaa tccgaatttt agtaaatctt
    41521 caggaatgat atgctgcatg acactttcgt cttcagaaag tttttggttt tgtgtaccaa
    41581 atccaatcgt cttttcgccc atacgattct tcacaatcgt ttcgatgcca tcaaatgcac
    41641 cacctacgat gaacaatatg ttcgtcgtat caatctgaat aaattcttga tgtggatgtt
    41701 tacgtcctcc ctgaggtggc acgcttgcaa cagttccttc tagaattttc agcaaggctt
    41761 gttggacacc ttcgccggaa acgtcacgag taatagatac attttcgctt ttacgcgcaa
    41821 ttttatcgat ctcatcaata tagatgatcc ctttttctgc acgttccaca ttgtaatcag
    41881 cagattgaag caatttaagc aaaatgtttt ctacatcttc ccccacataa ccagcttctg
    41941 tcaaacttgt cgcatctgcg attgcaaaag gtacattcaa tgtttttgct aatgtttgtg
    42001 ctaaaaatgt tttaccagac cctgtaggtc cgatcaagca gatattgctt ttttgcagtt
    42061 caacatcatc tgtgttttct tgtgcttgct gattgacacg tttatagtga ttgtatacgg
    42121 caacagctaa cgagcgtttt gcgcgatctt gtccaatcac gtagttattc aatacttcaa
    42181 gaatttctag tggtttaggg acttcagtga attcgcgtac agcttcttca taaaattctt
    42241 catcaatgat ttctttacat aggtcgatac attcattaca gatgtagacc cctggaccag
    42301 ctacgatctt tttcacttct tcttgggttt tcccgcaaaa agaacagcgt acggtctcat
    42361 tgctacttgg attgtcatac atggtcttca ccccttaact tgcaaaaagt atgcaagaaa
    42421 ctatcaaaga ctttacagtc ttttactatc ataacatagt ttagtaaaaa gaaaaagtgt
    42481 ttaacaaagg atcaactgac ctataccttt gcatttttta ctcttaacaa aaaataagga
    42541 actgtgacaa aatcgtgtca cagtccctta tttcgaataa acaattttct agaagtagct
    42601 tcttcagaaa tgatttatta cttgatttct attctttcgc ttctgtcgct gtacctgtga
    42661 tcaattcgat tgcttttttc attgtcacat catgttccag catatcttct gtcaacacgc
    42721 gtttgatttg ttcgattggc atgttgtatg tttctgataa ttcttggatt tctgcattga
    42781 tttcttcttc tgttgcttga agattttcag cagctgcaat tgcttcgatc acaagatttg
    42841 ttcttgtgcg catttctgct tcaccttcga attgtttatg caagtcttct tctgtagaac
    42901 cagttaattg atagtacatt tcaggagaga taccttgacg ttgcatgttg ttcaagaatt
    42961 cgtccattga acgatgtact tcatcatgaa ccatcacgtg tggcaattca acgatttctg
    43021 cgttttcaac agccatacgg atcgctgctt catcttttgc atcgtccgct gctttttctt
    43081 ttgtttctac taattctttg cgatattttt ctttcaattc gtctaatgtt gatacttcgt
    43141 catcaacatc ttttgcgaat tcgtcatcta attcaggcac ttcttttgct tttacttcat
    43201 ggattgtcac tttgaagact gcttcttttc cagcaagatc ttctgcttga taatcttctg
    43261 ggaaagttac atttacatct agactttcac ctgatttatg accaactaat tgatcttcaa
    43321 aacctggaat gaatgagcct gaacctaatt caagtgagta attttcgcct tttccgccat
    43381 caaacgcttc gccatctaca aagccttcga agtcgattac tactgtatcg ccattttcag
    43441 ctgcagcatc ttctttgata actaattcag cttgtgcttc ttgttcacgt ttgatacgtg
    43501 catccacgtc agcatctgtt acttcacggt cttgtttttc aacaactaga tctttatatt
    43561 gtcctaattt tacttctggt ttcactgtta cttcagcagt gattacccag tcttgacctt
    43621 tttccatgct ttcaacatcg atttttggtt gagaaacagg atcgatgcca gcttctttga
    43681 cagcagcttc ataagcttct ggtaatacag cattcaatgc atcttcatat aaagcttctt
    43741 caccgtacat acggttgaat acttgacgag aaactttccc tttacggaat ccaggtacgt
    43801 tcaagctttt tttcacttta ttaaacgcag ttgttaatcc tttttggatt tcgtcttgcg
    43861 caatcgtaaa ttttaaaaca ccatcattcg tgcctttttt ttcaaatgtt gcagtcattt
    43921 aattccctcc gagtttagaa attcatttta tacatcaaaa acgtttcatg cataccttta
    43981 aatagtacac taaccctttc aaattgtaaa catattgaat ggatagaatc cttgtttttc
    44041 ataacatttt tatctttttc actgataaaa tctaatggaa gaagatcatt tgctgcaaaa
    44101 ttttttctct tttttttaaa aaatcttgtt tttcatcttc tgtaccttca tacatcgttt
    44161 ttcctgtaca cgcctctaca gtcagttgaa accagcgctt cgggtcttcg atgtatgtat
    44221 catagacagg ataaacaatt gcagattgca acgtgaattc ttcatttaac acggaactaa
    44281 gcagcgcatc ttcattaccg taacgatctg aaaatacaca taattgctgg taacttgcct
    44341 gctgctgcgg ctttggcaga tcttttggta tgactttgac taacttttct tcaatcgtca
    44401 aatagaaaac aggatggcat tcgttcaatt gcctaagtgt ctccagtaat tttgcccttg
    44461 ctaaaatatg gacctctggc gatacaataa gtttactcgc tgtttagata aactcatgat
    44521 aaggaagctg ttcgatctca tcaatagacg caagctgacg tgcaggttcc aacgaaggaa
    44581 gttcctccga tttattgtgg agtgccttga tcttctgcct ctccatttgt ccggataatt
    44641 cttctgcaaa ttggattttt tcaatgaccc gctgctcgaa agcttcataa aaatctgtac
    44701 ttgctatcaa ttttctagca tataaaaaat cttgtgtact gattaacaag tcaaaataaa
    44761 attcagcaaa ctcctcattt tgaagatact gtttttcatg caagagtgct tgcttcaatg
    44821 cttctttttt ctcgtccaac tcgtaaagac aaaaaacaag caggctatta gcctcaaagc
    44881 tttctttcaa ctcgtaagct cgttgaaata attcttttgc ctgctgatat tgctggtttg
    44941 ctagtgcttg ttgtgctact cgcattaaat tctcatattt ttctggaaaa tcaatcggct
    45001 tcacgcagtg tcctcctctt gctcatgttc agctcatgtt caatagtagc aaaacaaaaa
    45061 aagcatgaca attaaaaata actgaagcac cctctaaaag ctagatttta gatctgactt
    45121 ttagaaggtg ctttcaactg ttactgcttt ttattgctca tcagctgttg acttcctggt
    45181 tgaatgcttt gatcagattg atcgtaacaa cacttgtatt agtgaaaaaa tcgcctagat
    45241 gttgcttttt ctgattaaag attgctggaa gataccctaa catcagcaaa ggaaatttta
    45301 gaatgaaccg gcaagcacct tctctaacta aaacggttga ccagctaagt tcttcttcat
    45361 caaagctgat gactcgaata ccaaagatca ttttcccaat cgtttgacca tgattgaatt
    45421 tcgtcaataa aataaaatac gctagataaa taagtaaggc tgtgaatccg tagatactca
    45481 gataagaatc tgaaaaatta agccaaccta gatttttggc aataccaagt gttaaacgcg
    45541 taatagctcc gatacacaaa agatcgacca agaaagcaaa cattcggata aaaaaacctg
    45601 catagaaata cttaggaaaa tcatttgctt ttggcggttc atttcttgtg tccgtatact
    45661 ttttccattt acgttgtttc tttttgattt cttcgggcgt caaaggctct ctttcaaaag
    45721 agctcagtac cttttgggaa aagttggagt caggtcctac agcaggctgc tgttgcttat
    45781 ctttttcttg ttccttattt tcatttgaaa gctctgacat gcttactcac ctccgtaata
    45841 atacattgct tttggtgatt ccgctgtccc tagattctca agaacggata agatctgact
    45901 agtctcagaa ggcttcaatc cctggaattc tgctagttta cttcctaacc atgtactagc
    45961 aaacccagat ggcgtggaag aatattctac tagttccgca tcttcaagct gttgttcctt
    46021 tcgcatagct tttaaagcat cttcaggaaa tcccaattca tcgactaaac ctacttcttt
    46081 tgcttggaca ccatcataaa tccttccatc agcaattttt ttgacttctt cttcagattt
    46141 attccgtccc tcgctgacga ttgctacaaa acgactatat gcgctgtcga tatatgcttg
    46201 aagcaccgct tcttcttctt ttgtctctgg tcgcgttcct gaacccatat ctttcaacgc
    46261 tccgctttta actgttgtat cttccacacc cagtttttct agaagtcctg aataattcaa
    46321 tcctgacatg atcacaccaa ttgagccggt cactgtttct tctgttgcaa agattttatc
    46381 tgcttgagca gaaatatagt agccaccgct agctgccatg tttttcatgc tgacatacat
    46441 tgggatatca tgttctttac gaatcgtatc caatttctta gcgatttccg cactttcgta
    46501 gacaccgcca ccaggagaat ttacttctaa aaagatacct ttgactgttg gatcttcttc
    46561 aatcgccttc agttgttcca taaaattttt atgattgtaa ccttcagaag caaataaacc
    46621 tgaagaccct cccgcagcaa tcgttccatc tactgataat tttacgattt tttgcgtact
    46681 gtctccctct tccaacacat ttgaagctag ttcttcatcc ccatataacc aactgttcaa
    46741 tccctcaatt tgatcgtttt cctgaggctt agtcaaacta gctgaaacta acgaaaccac
    46801 aaataatcct gcagcaatca gaactgctgc ccaacgtctc ttattcattc tttctccttt
    46861 ctaatacaag ttttttatga cgatcacagt ttctgactgc tcagaagtgt cgaaccgctc
    46921 tgctttttct tcccgcgcat acccggaaaa cgactctttt gtcaattcat cttctaccgt
    46981 aaactcacga gcttcagcaa cttccaaggc atcaggtgcg atttcttgga tgctatccca
    47041 gccagtatct aaaaatattt tcgtatcatc tgatacacca gctgatgctt cgaatttgga
    47101 caattgtttt tttaacattc ccagtgtcat gatctcaatt tttgaatcca tttttactcc
    47161 tcctctatcc gattactttc tattgtaccg aactcctgaa aaagatgata gataaaaacc
    47221 cattattttt tgacataaaa agagcatttg acaaagcatt tgatatatac caatttattt
    47281 tttattcttt ttttgttgac aagaacattc gcaaaaggtt atgattttaa atgtttccag
    47341 ataaaaaaca aaagaggagg atagttatac cttttaggat agcgccaggt ctgtgtaaac
    47401 agatgacgag gagagggttt atcgaaagat tcggcggatg gccctaggga ctgcactcta
    47461 cagaaaatcc acaaaaaata tctgcaaaga taaaacaaaa ggattttcct gcagctggaa
    47521 gcattcatac gaattcatta tagaaagtag gatgtttttt atgtgcggaa ttgttggaat
    47581 gattggatta aaaaatgtaa caccaggatt gattgacggt ctagaaaaat tagaataccg
    47641 tggttatgat tcagctggta tctttgtctc agatggcaca actgattatc tggtcaaagc
    47701 acaaggcaga attcaaaatt tgaaaaacaa aataaatatt gatactacag gaaatatagg
    47761 tattggtcat acacgctggg caactcacgg gcaaccttct gaagaaaacg cccatccaca
    47821 tacttcccaa agtggacgct tcgtgctcgt tcacaatggc gtaatcgaaa actttgaaga
    47881 acttaaaatt gcttatttag caaatgacca ctttattggt gagaccgata ctgagattat
    47941 cgctcatcta attgaaactt tcgcgaagga tactacaacg caagaggcgt ttttaaaagc
    48001 tttgcgggtc atcaaaggtt cttacgcttt cgctttgatt gatcggacag cacctgatgt
    48061 tatttacgtc gctaaaaata aaagtccact attaatcgga ctcggcgatg gattcaatgt
    48121 gattgccagc gatgcaatgg ctatgcttgc tcatacgaag gaattcgttg agattgaaga
    48181 tgaagagatg gttaccgtca catcagaaaa agttattatt caaaattttg caggtgacat
    48241 cgtagaacgt tcttcattcg aagcacaagt agattcttca gatatcgaga aaggtaccta
    48301 tcctttttat atgctgaaag aaatcgacga acagcctatt atcatgcgtc gtatcgctca
    48361 aaaatacgta acagaagaca atcgtgtctc tcttgatcaa aagctggtcg atacattgtc
    48421 tgatagcgat cgaatctata tcgttgcttg cggaactagt taccatgcgg ggttagcagg
    48481 taaacagact ctggaaaaat tgacacagat ccctgttgag gttcatttag ccagtgaatt
    48541 tggctataac acacctcttc tttcaaaaaa accattcttt attttcttga gtcaaagtgg
    48601 cgaaacagca gatagccgcc aagttctggt aaaaatcaac cgtctcggct acccttcact
    48661 tacgattaca aatgttgctg gttctactct ttcgcgggaa gcatccttta cactgctatt
    48721 gcatgctgga cccgaaatcg cagtagcatc aacgaaagct tatactgcac aaatagctgt
    48781 actaacttta ttagccaaag ctatcggtga taaaaaagaa tttgaaactt ctcttgtatt
    48841 cgatatcact catgaattga gtttagttgc taatgcgatg gaatcggtca tcgcccaaaa
    48901 agattattta gaagagttgg cagaagtata tctcagcgat acaagaaatg ccttttacat
    48961 tggacgtggc gctgactaca acgtttctct tgaagctgct ttgaaattga aagaaatcag
    49021 ttatatccag gcagaaggtt ttgccgctgg cgaattgaaa catggaacga ttgctttgat
    49081 cgaagaagga acaccagtga ttggaatcat cagtgaagaa gtgactggtg cgcatactcg
    49141 aggaaacctg aaagaagtcg aaagccgtgg cgctaaaaca ctagttattg tctcagaggg
    49201 attagaaaag gaaagtgacc agctggtgct accaactgtc cacccttatc taactactct
    49261 aaccacagtc gtaccgactc aattacttgc atattacgca acgctattac ggggattcga
    49321 cgttgacaaa ccacgtaatt tagcgaaatc agtgacagta gaataataaa agaacaagga
    49381 ccagtgtcag acatctgaca ctggtccttg ttcttttatt ttttatgaaa atat
//
LOCUS       DASHXG010000015        48823 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.015, whole genome shotgun sequence.
ACCESSION   DASHXG010000015 DASHXG010000000
VERSION     DASHXG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.015"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            23..646
                     /locus_tag="U2R59_001018"
     CDS             23..646
                     /locus_tag="U2R59_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965427.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="U2R59_001019"
     CDS             1096..2145
                     /locus_tag="U2R59_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965428.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="U2R59_001020"
     CDS             2142..3023
                     /locus_tag="U2R59_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965429.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="U2R59_001021"
     CDS             3026..3796
                     /locus_tag="U2R59_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965430.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="U2R59_001022"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="U2R59_001022"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEM8965431.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="U2R59_001023"
     CDS             5107..6270
                     /locus_tag="U2R59_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8965432.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="U2R59_001024"
     CDS             6387..6797
                     /locus_tag="U2R59_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8965433.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="U2R59_001025"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="U2R59_001025"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8965434.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="U2R59_001026"
     CDS             9370..9654
                     /locus_tag="U2R59_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965435.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="U2R59_001027"
     CDS             9814..10050
                     /locus_tag="U2R59_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8965436.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="U2R59_001028"
     CDS             10047..10445
                     /locus_tag="U2R59_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEM8965437.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="U2R59_001029"
     CDS             complement(11112..12056)
                     /locus_tag="U2R59_001029"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEM8965438.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="U2R59_001030"
     CDS             complement(12352..13296)
                     /locus_tag="U2R59_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965439.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="U2R59_001031"
     CDS             13517..14731
                     /locus_tag="U2R59_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8965440.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="U2R59_001032"
     CDS             14753..16768
                     /locus_tag="U2R59_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HEM8965441.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="U2R59_001033"
     CDS             complement(16851..18224)
                     /locus_tag="U2R59_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEM8965442.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="U2R59_001034"
     CDS             complement(18250..18534)
                     /locus_tag="U2R59_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8965443.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="U2R59_001035"
     CDS             complement(18536..20551)
                     /locus_tag="U2R59_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8965444.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="U2R59_001036"
     CDS             complement(20730..21035)
                     /locus_tag="U2R59_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HEM8965445.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="U2R59_001037"
     CDS             complement(21124..22155)
                     /locus_tag="U2R59_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8965446.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="U2R59_001038"
     CDS             22362..23237
                     /locus_tag="U2R59_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8965447.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="U2R59_001039"
     CDS             complement(23389..24231)
                     /locus_tag="U2R59_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8965448.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="U2R59_001040"
     CDS             complement(24323..26200)
                     /locus_tag="U2R59_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8965449.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="U2R59_001041"
     CDS             complement(26197..27618)
                     /locus_tag="U2R59_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8965450.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="U2R59_001042"
     CDS             complement(27621..31010)
                     /locus_tag="U2R59_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEM8965451.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="U2R59_001043"
     CDS             31267..32658
                     /locus_tag="U2R59_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965452.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="U2R59_001044"
     CDS             complement(32731..33378)
                     /locus_tag="U2R59_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEM8965453.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="U2R59_001045"
     CDS             complement(33386..34072)
                     /locus_tag="U2R59_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965454.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="U2R59_001046"
     CDS             complement(34078..35151)
                     /locus_tag="U2R59_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965455.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="U2R59_001047"
     CDS             35373..36047
                     /locus_tag="U2R59_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965456.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="U2R59_001048"
     CDS             36052..37392
                     /locus_tag="U2R59_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8965457.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="U2R59_001049"
     CDS             complement(37541..38527)
                     /locus_tag="U2R59_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HEM8965458.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="U2R59_001050"
     CDS             39251..40282
                     /locus_tag="U2R59_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8965459.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..41923
                     /locus_tag="U2R59_001051"
     CDS             40391..41923
                     /locus_tag="U2R59_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HEM8965460.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            42062..42874
                     /locus_tag="U2R59_001052"
     CDS             42062..42874
                     /locus_tag="U2R59_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HEM8965461.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            42864..43349
                     /locus_tag="U2R59_001053"
     CDS             42864..43349
                     /locus_tag="U2R59_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8965462.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            43372..43917
                     /locus_tag="U2R59_001054"
     CDS             43372..43917
                     /locus_tag="U2R59_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEM8965463.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43990..45633)
                     /locus_tag="U2R59_001055"
     CDS             complement(43990..45633)
                     /locus_tag="U2R59_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEM8965464.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45762..47990)
                     /locus_tag="U2R59_001056"
     CDS             complement(45762..47990)
                     /locus_tag="U2R59_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8965465.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(48023..48502)
                     /locus_tag="U2R59_001057"
     CDS             complement(48023..48502)
                     /locus_tag="U2R59_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965466.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        14861 a         8993 c         9181 g        15788 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga attaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctattc tttatttaat ggaacaacct gctttgtctg tttctcaatc
    40861 atttttagac aaaaatgaaa tttcttatat gacccatact tctggtacaa ctggtatccc
    40921 taaacttatt tgtcattctg ctcattctat gggatggcgg acgaaatggc aaaaaacagt
    40981 tttcacaaaa atttcggaaa agaaattaat cgcttttcac atctctccag tgcattccag
    41041 attcaatatt ggtatctctt ctttgatgtc catgggattt cctatgatgc ctttagcaaa
    41101 cgcacaaagt tcaaaagttg ttcatatgtt ggaagctcac cggccaattg cactagagac
    41161 ccatccgaat aactttgttc agtggcgttt tactgctaag gagcatccag aagctttttc
    41221 gggtatccga tactatcact ccacttttga tgctataaac aaccagacaa tgaagacatt
    41281 tttgcgaacg tcgatggcac aggatgcggt atttcttcaa gtatatggcc aaagtgaatg
    41341 cggaccaatg attcttaagg ctcatacact agagagtttg aaaacaagtg atgcaagaga
    41401 tatgggcgtt ggactggaag acatgacaag cgctcggatt acagattcag ttgggaatgt
    41461 cctacctgaa aacacagatg gtcatataca attactgtct aaaggacggg ctttgactta
    41521 ttacaaggaa gatgcacggt tccaggaaaa tgtttatggc gattggtggg atagcggaga
    41581 ttacggtttt atggataagc atggccacct atttttgaaa gatcggcaag tggatttgat
    41641 cgaaacgatc aatagtacat tagctattga agacttttta ttagattcgt tagatttttt
    41701 ggcagaagta gtgattgtaa gggataaaaa tcattctcca caaccgatta ttgctttagc
    41761 tcctgataaa gaaatggatt ggaatcgatg gtgggagcaa gtccatgaac ttcctcgctt
    41821 gaacgtccct atcatccgtg attttgatgc aatcccgcga acagctacaa tgaaagtgca
    41881 acggcttcaa atcgagaaag aattaaaatc acaaaagtcc taactattta aggaaagaaa
    41941 gatccatttt ggtctttctt ttctttttgt ttttttaaat tggatgagat aaaaatatgc
    42001 caattggctg tttttctttt ttgaaaattt cgttatactc ttattcatgg aggaaaatgt
    42061 tatgaaaaga atcttgacaa ttggcggttc tgatccattt gctggtggag gaatccaaac
    42121 agatttaaaa acttttgaga attttggtct attcggacta agcgccttga cttctatagg
    42181 ggcactagat attaatgagc gatttatgct ggaatctata tctttggaat tgcttaaacg
    42241 acagttagtt tcgattgata aaatgacttc attagatggt atcaaaattg ggttattgaa
    42301 ttcaagtgaa gcaatcatgg ttgttcgaga cttcataaaa acaaaacaaa atatcccaat
    42361 cattttagac cctgttttgg cattcaaaga aactgaagct gtgatcaatc aattgtatat
    42421 ttcgcagctc atcgaagaac tttttccact tgttacgatg attacgccta atttggcaga
    42481 agctgcttta ctttctggtc aagctcttcc ctcttcgtta acagaaatga tccatctcgc
    42541 taaagaactc actgcttcag gaacaaaaaa cattgtgatc aaaggcggca caaggatggc
    42601 tggagatgaa gctgtggatc ttctctattc aattgatcat tatgaggtat tttctcataa
    42661 aaaaatcgac actacaacag taaacggggc cggttgtgcc ttttcttctg caataacagc
    42721 gaatcttgtg ttaggggcag attttaccaa agcagtagca gaaagtaaaa aatttgttgc
    42781 ccattgtatt tctaatggcg tgctgatgaa cgatcatacc ggaagtgtct ggtctggcgg
    42841 tattcaaaaa ggaggaatga gaaatgaaaa ctaagcaatt aacgatctat gctatgctga
    42901 ttgcgttgac agttgccctt tcattaacaa ttttgatccc tgtaccggct acgaatggat
    42961 ttgtgacatt atgcgaggcc gggatctata ccgctgcttt tctttatggt ccaacgggtg
    43021 gattagttgt tggtgcttcc agtggtctat tgatcgattt gatttcagga tatccgcagt
    43081 gggcagtttt ttcattagtg atccacgggt tacaaggata tgttgctggt tctttcagca
    43141 aatcttctac tcgtatgtgg ggattagggc ttttattagg aagcttagtt atgatcatcg
    43201 gctatggtat cgccggttgg attttatatg attggccggc tggagtggct tctataccag
    43261 gaaacatctt ccaaaatctg attggaatgg gacttgcctt tcctataact gcaagtcttc
    43321 aacgtattca agcacggaag caatattaat tgaaaaagaa ggttttagaa aatgaagttg
    43381 tcagaaaaag aattaaaaga ccaattgact gaaatagtta atgacatatt ggctgaggca
    43441 cacttgaaaa aaggtgatct ttttgtttta ggatgcagca caagcgaagt cgttggagga
    43501 catattggaa aaaattccag tgcggaagtt ggtcaatgga tcatccgtac gttaaaagag
    43561 ttgttggatc ctaaagaaat tgcgctagct gtccaaggtt gtgaacattt gaaccgagca
    43621 ttagtagtag aacgaacagt ggcagaagca aaaaatttcg aaattgtctc tgttgttcct
    43681 gcactacatg ctggaggtgc ttgttctgtt gctgcttttg accagttcaa tgatcctgtc
    43741 gaagtggaac acgtagttgg acaagccggt atcgatatcg gtgacacatc aatcggtatg
    43801 catatcaagc atgtccaagt acctgtcaga cctcgtttga aaacccttgg acaagctcac
    43861 gtgacagccc ttcgctctcg tcctaaatat atcggtggtc ctagagcgaa ttattgaaat
    43921 gagtaattga cagagcaatc tgaaaaactt cctcgcaaag tccaactaat gaactttaac
    43981 gaggaagttt tacttgtttg ttttatataa ccgagcttca taaggtgcta gtatgccttt
    44041 agcttcaaat tctccgctag aggaatttga caagagtaat gtccaggact gatctgcttc
    44101 ttttggaagt tcatagtcag caagtgattc tgttaagttt accataataa gatattgttc
    44161 atcttctaaa tatctttcat agacataaag ttgtggatgt tcatgaagat attctttata
    44221 agaaccgtat atcagacctt tattggtttg tctaatgcgg atcatgttct tatagaattg
    44281 caggaccgac tctggttcat attcttgttg ttctacattg atcgttttgg tatttggatt
    44341 agtgatcagc caaggttcat gtgtagaaaa accagcatat tgttccgaag tccattgcat
    44401 gggtgtcctg ctgttgtctc tcgttgtttc acgaatgata tccaatgctt cttctcttgt
    44461 cttaccttcc gcaagcagcc ttttataaag tcttttcgaa tctactgcat caacttgatc
    44521 gatcgattca aagggcatat tcgtcattcc gatttcctgt ccttgataaa taaatggcgt
    44581 accttgcaaa aagaaataca tcatagcgat tgcttttgca gacatagccc aaaaatcggg
    44641 acgagtatct ccaaacactg aaacggcacg aggaacatca tggttttcca tatataaagc
    44701 gttccatccg ataccatcca atgaagtttg ccaagcgctt aatgcatgtt tcaatttaag
    44761 gacatctaat tgcccttctt tttcttgctg ccagatatgg atatgatcaa attcgaatat
    44821 catatcgaaa taaccgtctt tccctaccca ttgtggtcct tcttctgcag tgacaccact
    44881 tgcttctccg acagtcatga tatcgtactc ttcaaaaaca tgtttcaaat cggtcaaatg
    44941 ttcttcgatt cctgagacat tttgaaaggg tgagaaaggg ttctctgtgg cttttactga
    45001 atattcatct ttttttacat gagaaatcgc atctaaacga aatccatcta tccctttatc
    45061 caaccaccat cggatcatat tgaatagttc ttctttcaat ttctcgcttt cccaatttaa
    45121 gtctggttgt tcttttgcaa aaacatgcag ataatactgt ccagtttcat gagaatactc
    45181 ccaagcagaa ccgccgaaaa tcgatgtcca attattcggt tctttgccat ctaccccgtc
    45241 gacccaaatg taataatcgc gatacgggct ttctttagat tttttcgatt cttcaaacca
    45301 ttgatgctga tccgaactat ggttgatgac aagatccata atcactttga tccctaattc
    45361 atgtgcttct tttagcaata aatcaaaatc ttccatcgtt ccgaatctct cttctatatc
    45421 ttgatagtca cttacgtcat aaccattatc gacaaatgga gattgataga tcggattgat
    45481 ccagataaag ccgataccaa gatctttcaa ataattaagt ttttcacgga tcccattgat
    45541 gtctccttga ccatcgccat tgctatcttt gaaactagca ggatagattt gatagcctac
    45601 tgcttctttc caccattttt gttcttgtat catatcgttt cactccttta acggtccctc
    45661 ttgattataa ccgattctat tttagaagta tccttgttac cggtaactag aaacgaaaag
    45721 ctcaacgaat ctgctaagtg cgttcgttga gctttatttt atcatagata gcgggcaatc
    45781 agttgaatca tttgcttggg aaattcattc aagtcagtaa tatctacaaa acgactttca
    45841 ccgtagatcg acttgatttc ttctttgtct tggccaatag ctgcggagac aaataggatt
    45901 ccttgacgtt catattcttt caaaacagac tggatatctt cttttgcttt tttgcctgta
    45961 taatccggca acgcttttgg ctgaccgtca ctaatattaa gcaacagttt ggttgttgcg
    46021 gattgtctgt ttaatttttc tgctgctaaa cgaagtgcag caccatcacg attgttttgc
    46081 cttggtttca tagtgactaa tttttcattt aaccattgaa atccgtcttc aaattcttta
    46141 taagaaaaca aagaagtctt ttctcttgac gaacggtctg ctgtatctcc gtaaatcaac
    46201 aatgggatat cgactttctt agaaaattcg gcaatggcaa tcgctgcttt ttttgccgct
    46261 tcgatccgat catcccgtat cattgaccca gattcatcga tccgtacagc taccgctaaa
    46321 gaaggttgct catgtggcgg gttctttttg tcaaaatttc tcaaatcacc atatgctact
    46381 ttgcttgcat tgaaccgctg accttcgtat tttccttttt ggtacgtctc tgtttgttca
    46441 ttatccagta actctaaaat ttgccggcta agtgattcta ctattggcat tacttgcatg
    46501 tgtagctcac gtgcttccgg cgtttttcct tggaaagctg gtcggtgaac gatgagacct
    46561 tctttttcat gaatcgtttc cttcatgatt tgtcgcgctt ctttattcag ttgcttcttg
    46621 atttccttat catgtgcttc catgtcagaa gcagacattt cttgagaatc atctcctgtt
    46681 tgttgttctt tttgattttt tccttcgata tcgctactgc gttctttttg catttgagga
    46741 ggaatctcgt ttttttctat tgtttcttct tgtttctctt ctccctcatt tggttcttca
    46801 gcagacaacg atttcttttc atctaagcgc agaatttctt cagcattttc agtgatgttt
    46861 cgttcatttg cttcttcggc gctaatggtt ctttcttttg tatgctcaga ttgaggatga
    46921 ccccattttt cttttctcaa tatgtcctga agttccagta gcaatccact gtcagacaaa
    46981 gcttgttcaa gaattgccaa ttcatctgaa tcagtggata atttatacaa aacttttgga
    47041 taaatcgact ggagtaaatc ttgtccttgc ttataggtat ttgcccaata aaaataagaa
    47101 cgcattcctg ctacaccttt gatggcgtta gcttttgcag tttcatccaa caaacggata
    47161 atctctgcca tctttaagag aagttcttgt ttttggatca tagttttcgc catcgcacgt
    47221 tctgccatga cttctaaggc aggaagatcc attttttccg catgttgcat ccgatctctt
    47281 aaagattcat ttaatgggcg atttccttgg taatttcgat ttgtagtgat cacaatgacg
    47341 caatctggat ggcgacgaat gattcctgtc ggtaaattca acatcccatt tggttcgagc
    47401 gctgagttaa gtgccacaag aacagaggca tctcggatga cagtcggctc ttgaatctct
    47461 aataaatagc ctttttcaat cgctcgaacg atttcagaag ggtaatagct gtaatggatt
    47521 gcatctggat aatcagcttc gatcctttga actagctctg ctaatttttc tttagcagaa
    47581 aaaggatcaa tgccgtaatg gttctggatc agtgtcagta cagcttcaag tgtatctgtt
    47641 tggtaaatag cttctagtaa ttcttggtct tgttccttat tagaatctac tacaggtaat
    47701 aaggctccga aaacatctga tttgtccata tctgcaaaac aggtcacttt tgtataggga
    47761 agttgcagat cagcagatag tgctttggct aattgtgtct tccccgaccc ggcatctcct
    47821 tccaaaagta cgttactgat tttcatttca ggatcttgcc aattcccttt gatttcggag
    47881 gcgatccgcc attcttctgc acttgtccga tggcttttcg gtttcttcca gatcatttgc
    47941 ttttctagcc gtgaaaaggt tcggttttct gttagtgaga aattctccat gcttctcttc
    48001 cccttttgat catctctgtc tattaatatc ctagctcatc taaaagacgt tttaaaatac
    48061 ggaatcgttc cccaatcagt tctccgtctt tttgtagtgt atcgtaatac aaaatgatgt
    48121 cttcatcgat ctttggattt ttggtatcta cttctaccgt cattcggttc ccttgtaatc
    48181 caatgatgtc tacgactgga ttttctggat cataaaattt ttcataacga taagcatctt
    48241 ggaagtataa acttccttgc gcagctaaga tcgctaaatc taaaatacgt gtgattggta
    48301 attcttccga ctgtcgtgac catttttctc cagtatgtcg ccataccttg cctgagatat
    48361 cgacttttcc acgatcattc cactgagcaa ggcccagtga aagccctttt gcatccatat
    48421 ttaatgcatt tcttccatca actttatcat agtcttctac aacgattact ggtttatgtt
    48481 ttaaatttgt tggtatttcc attattttaa ctcctcatcc ttttattttt agtaaataag
    48541 taaattagta gtttactcat ttactaaact atatgcgaca ttatagagga ttgaagtgag
    48601 gattgcaaag aaaaagagct tcattgatag aaataaaaac accatctcgt tcttttacac
    48661 gctcattagt aacatgtaga aagtccaaga tgatgttgga atattttggc tctatacttt
    48721 ttgatgttgg tgaacttcac caacatcttt tttgtattct taattgtcaa attaagttag
    48781 acagatcatc aatacttacg taactcaaaa atacttccaa agg
//
LOCUS       DASHXG010000016        48543 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.016, whole genome shotgun sequence.
ACCESSION   DASHXG010000016 DASHXG010000000
VERSION     DASHXG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.016"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(13..378)
                     /locus_tag="U2R59_001058"
     CDS             complement(13..378)
                     /locus_tag="U2R59_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965467.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
     gene            complement(553..2688)
                     /locus_tag="U2R59_001059"
     CDS             complement(553..2688)
                     /locus_tag="U2R59_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8965468.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2771..4426)
                     /locus_tag="U2R59_001060"
     CDS             complement(2771..4426)
                     /locus_tag="U2R59_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8965469.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4428..4742)
                     /locus_tag="U2R59_001061"
     CDS             complement(4428..4742)
                     /locus_tag="U2R59_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8965470.1"
                     /translation="MNLLFQSIKSITVPELKEKILENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4912..5172
                     /locus_tag="U2R59_001062"
     CDS             4912..5172
                     /locus_tag="U2R59_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEM8965471.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5186..5500
                     /locus_tag="U2R59_001063"
     CDS             5186..5500
                     /locus_tag="U2R59_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HEM8965472.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5985..6539)
                     /locus_tag="U2R59_001064"
     CDS             complement(5985..6539)
                     /locus_tag="U2R59_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HEM8965473.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6665..8593)
                     /locus_tag="U2R59_001065"
     CDS             complement(6665..8593)
                     /locus_tag="U2R59_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEM8965474.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8899..9615)
                     /locus_tag="U2R59_001066"
     CDS             complement(8899..9615)
                     /locus_tag="U2R59_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEM8965475.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9616..11439)
                     /gene="glpO"
                     /locus_tag="U2R59_001067"
     CDS             complement(9616..11439)
                     /gene="glpO"
                     /locus_tag="U2R59_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEM8965476.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11453..12949)
                     /gene="glpK"
                     /locus_tag="U2R59_001068"
     CDS             complement(11453..12949)
                     /gene="glpK"
                     /locus_tag="U2R59_001068"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEM8965477.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13085..14545)
                     /locus_tag="U2R59_001069"
     CDS             complement(13085..14545)
                     /locus_tag="U2R59_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965478.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14535..15830)
                     /locus_tag="U2R59_001070"
     CDS             complement(14535..15830)
                     /locus_tag="U2R59_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8965479.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16162..16839)
                     /locus_tag="U2R59_001071"
     CDS             complement(16162..16839)
                     /locus_tag="U2R59_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HEM8965480.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16869..17960)
                     /locus_tag="U2R59_001072"
     CDS             complement(16869..17960)
                     /locus_tag="U2R59_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEM8965481.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18061..18495)
                     /locus_tag="U2R59_001073"
     CDS             complement(18061..18495)
                     /locus_tag="U2R59_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8965482.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19079..20536)
                     /locus_tag="U2R59_001074"
     CDS             complement(19079..20536)
                     /locus_tag="U2R59_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8965483.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20533..22428)
                     /locus_tag="U2R59_001075"
     CDS             complement(20533..22428)
                     /locus_tag="U2R59_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8965484.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22486..24261)
                     /locus_tag="U2R59_001076"
     CDS             complement(22486..24261)
                     /locus_tag="U2R59_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8965485.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24311..25807)
                     /locus_tag="U2R59_001077"
     CDS             complement(24311..25807)
                     /locus_tag="U2R59_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8965486.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(26001..27623)
                     /locus_tag="U2R59_001078"
     CDS             complement(26001..27623)
                     /locus_tag="U2R59_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEM8965487.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(28073..29386)
                     /locus_tag="U2R59_001079"
     CDS             complement(28073..29386)
                     /locus_tag="U2R59_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEM8965488.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(29631..29855)
                     /locus_tag="U2R59_001080"
     CDS             complement(29631..29855)
                     /locus_tag="U2R59_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965489.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29875..30297)
                     /locus_tag="U2R59_001081"
     CDS             complement(29875..30297)
                     /locus_tag="U2R59_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEM8965490.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(30439..31149)
                     /locus_tag="U2R59_001082"
     CDS             complement(30439..31149)
                     /locus_tag="U2R59_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965491.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(31167..31663)
                     /locus_tag="U2R59_001083"
                     /pseudo
     CDS             complement(31167..31663)
                     /locus_tag="U2R59_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(31700..32152)
                     /locus_tag="U2R59_001084"
     CDS             complement(31700..32152)
                     /locus_tag="U2R59_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8965492.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(32287..32892)
                     /locus_tag="U2R59_001085"
     CDS             complement(32287..32892)
                     /locus_tag="U2R59_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEM8965493.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(33342..33962)
                     /locus_tag="U2R59_001086"
     CDS             complement(33342..33962)
                     /locus_tag="U2R59_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8965494.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33964..34833)
                     /locus_tag="U2R59_001087"
     CDS             complement(33964..34833)
                     /locus_tag="U2R59_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HEM8965495.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34856..35263)
                     /locus_tag="U2R59_001088"
     CDS             complement(34856..35263)
                     /locus_tag="U2R59_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEM8965496.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(35282..36571)
                     /locus_tag="U2R59_001089"
     CDS             complement(35282..36571)
                     /locus_tag="U2R59_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8965497.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(36598..36900)
                     /locus_tag="U2R59_001090"
     CDS             complement(36598..36900)
                     /locus_tag="U2R59_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8965498.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(36925..39018)
                     /locus_tag="U2R59_001091"
     CDS             complement(36925..39018)
                     /locus_tag="U2R59_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEM8965499.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(39507..40235)
                     /locus_tag="U2R59_001092"
     CDS             complement(39507..40235)
                     /locus_tag="U2R59_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HEM8965500.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(40381..43002)
                     /locus_tag="U2R59_001093"
                     /pseudo
     CDS             complement(40381..43002)
                     /locus_tag="U2R59_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(43116..44447)
                     /locus_tag="U2R59_001094"
     CDS             complement(43116..44447)
                     /locus_tag="U2R59_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965501.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(44413..45891)
                     /locus_tag="U2R59_001095"
     CDS             complement(44413..45891)
                     /locus_tag="U2R59_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8965502.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(46196..48031)
                     /gene="tdc"
                     /locus_tag="U2R59_001096"
     CDS             complement(46196..48031)
                     /gene="tdc"
                     /locus_tag="U2R59_001096"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEM8965503.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            48257..>48543
                     /locus_tag="U2R59_001097"
     CDS             48257..>48543
                     /locus_tag="U2R59_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965504.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGR"
BASE COUNT        13913 a        10427 c         8108 g        16095 t
ORIGIN      
        1 taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtattcaa aagatttatt
       61 tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg taatcaggaa
      121 actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct tttctgataa
      181 aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga aaaagaccca
      241 tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt gccaaatctt
      301 taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg caacttcttc
      361 tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta ggagtttacc
      421 atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa aaagaacaaa
      481 acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt ctttttattt
      541 tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc ctctagatat
      601 cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa atggatataa
      661 gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt ggcagttttc
      721 taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct cttctgtttg
      781 ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta gtattttcaa
      841 caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg gtcggatcga
      901 tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg tgattgctcc
      961 gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt agtcatcgaa
     1021 acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat tctcgtcacc
     1081 tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt gtgccagggt
     1141 ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta ccttttcaac
     1201 aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg tgggttgcca
     1261 agcataagct gagccatatc gtttttcata aattctttca aacaactgat gctcatccac
     1321 ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta aaagtttcct
     1381 tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga ataattccaa
     1441 ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt ttgcttgttt
     1501 caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa gcctatcgat
     1561 caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt tagaaaggac
     1621 tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa acaaaggatc
     1681 tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct gctccgatac
     1741 attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct ctgctgaaag
     1801 ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta atgatggtag
     1861 gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca agtcatcgga
     1921 tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga tagcagaggt
     1981 tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat cccgaatgat
     2041 tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg tctcatcttg
     2101 gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa aaaacttgac
     2161 caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat cgattttatt
     2221 ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt cggcaattgg
     2281 tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg ctgtaccgat
     2341 ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc caaagtaggg
     2401 acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct gtttgatatt
     2461 catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca ggttatctaa
     2521 gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact ggtttccttc
     2581 tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta gcttttgata
     2641 cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac acattctcct
     2701 ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa tgcaagcttt
     2761 ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt tgatataaag
     2821 aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt ctttccgcta
     2881 gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg tctaattcat
     2941 ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat ttgccctttt
     3001 ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt tctgtcggca
     3061 attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct gcatatccta
     3121 gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat tctaattccg
     3181 gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg atccgtttat
     3241 ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct ggatggaaga
     3301 tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct tttcctgata
     3361 catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt aaaccggtgg
     3421 atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct tgatttcttc
     3481 gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct ggtgaagcaa
     3541 gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca tcccccaccg
     3601 cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc ccgcgtatgc
     3661 ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca atggataaaa
     3721 taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc ccgtggtctt
     3781 caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac aattcttttt
     3841 ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct tgttcgatca
     3901 ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg atgaatcctg
     3961 caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact ttatcgatat
     4021 ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga atcgatggaa
     4081 caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg tgtttttgac
     4141 cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact tcatgatttg
     4201 gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca agaagatttt
     4261 cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca aaagaaacat
     4321 acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga agccgtgtag
     4381 cagcagacat tccacctgct acacctccga caataacgat tttcatctta tttccctcct
     4441 actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc ataaccagat
     4501 ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat cacatagacg
     4561 gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt tttagctcct
     4621 tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc tggattttcc
     4681 aaaatctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa tagcaaattc
     4741 attttctgca cctcatttac atttttataa atacctcatg gggtatatta aacaggagct
     4801 ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta tatttgcata
     4861 aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt tatggagatt
     4921 gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg tggtatccaa
     4981 aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag cgctgttcgt
     5041 tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa ttgctttgag
     5101 aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat caagatgatt
     5161 attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg aattagaaaa
     5221 atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag aaacgacgat
     5281 tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca atgcagaatt
     5341 cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg ctaatcatat
     5401 ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc ttgatttagt
     5461 tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg ttgcgacaga
     5521 agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct ggaaaaccgt
     5581 gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat
     5641 agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     5701 gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa aaaaacggga
     5761 aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc tgattgaaca
     5821 ccgtttacca agaggttgtg agcctaccat ttaactccga atcacaagaa ataatttcaa
     5881 aaacaacttc tcctgttttt ggtttggttg gcttattatc gagaagtagc tactgggagt
     5941 ctatttatca aaaaaaggaa tgcgacatag gtcacacccc ttttttattt tctttgaaac
     6001 atctttcggt actcgacagc atacaagaca aaagattgta aaagaccgta agtgatgacg
     6061 gcaaaaatga ctctcaccca cagcgttggt aattctggga aaagcagcaa aaggatcatg
     6121 ccaacataga tgacagcagt cgctactttg ccataccact tcgctccact taatttgata
     6181 tttttagata gcccgattaa tccagctaca aacataaagc cttcttttat caagaataga
     6241 ccaaacaaca gccaaagcca cggtcgatac catgccatag acaaaatcag aaaaagttgt
     6301 gtcaatttat ctgcaaacgg atcaagcacc ttccctaagt ctgttacctg attatatctc
     6361 cgagcaatga ccccgtctag ataatcagac aaacctgaga caacaatgac cgctcctgct
     6421 atataaaatg actgtctcag cacaaaataa agataaatcg gcagcaaaaa aatacggaat
     6481 atcgataaaa gattcggaat cgtttgtatt tctttacgcc agtctgtgct taatttcatt
     6541 ttatcgccct acctcctcag cactcttttc tttttatttt agcttacacg gggaataaaa
     6601 ccaatgattt cactgttttt atttttcttt acagccactg atattatgag ctaatttgag
     6661 ataatcactt gctgttttca tcgtttactc ttctttcttc ctgtcgtttg cgcatttctt
     6721 ttactagtac tttatgagct ttttttgatc ctcgctctag gtcacgctgc cgtttacgtg
     6781 ttttataatc gataaacaga ctgtctaaat cgtaacctgt cgggtacaga tcttctgctg
     6841 aacgcaccag acgaacacgc tgacgaggca cgtggattat ttttttgtct aaatatacat
     6901 caatcgtatc ttcacctata tcttcataaa ctaacgcttc tttttggtat tcattgacaa
     6961 atatccgatc accttttgca aagagctggc gttctttttt attctccttc ctatttgtaa
     7021 ctgctgtctt aggaagaaat tcttttttct gtgtccgata ggctttttcc gccaagtaac
     7081 gctctgcttg atggatcaat ttcatcgaca tatccatttt atgagcaatc cacaaagctt
     7141 ggctttctcc tgtttctcca acccgcaact gatatttagg acgaagtgct tcccgatcga
     7201 aagccatagc agccggcaca aaatcttcat gatctccggc gaatttcttg atttctccat
     7261 aatgggtcgt ggcaatgatc aatgcccctt gctcatacat agattccatg attgcgatcg
     7321 ctagtgcagc cccttcattt ggctctgttc cactgccaat ctcatctaaa agtaccaacg
     7381 tattcctttt tatctttttc aaaatagcag cgatgttttg catatgacca gaaaatgtac
     7441 tcaacgcatt ttctaaattt tggtggtcac cgacatcgac gaaaatctca tcaaagacag
     7501 caagctctgt cccttctttt gccggaactt gcataccgaa catcgccatc aaagtcaata
     7561 aaccgactgt cttcaacacg actgttttgc ctccggcatt tgctccggtg ataatcaagc
     7621 ctcgatagtc tttaccgatt tcaacatcca atggtaccgc atgctcaggt aaaaatggat
     7681 gtctgccttg cttgataatg atatgttccg atttattgat tctaggtgtg cttccattga
     7741 tttctcggct aaattttgcc cgagcaaaga tgatatctaa caccgtgatc gtttcgatca
     7801 ataaatcgat cacttcttcg ttttctgcga tagcaccagt caatgccgcc aggacttgat
     7861 attcttcact gatttcttca gcttttaaca actgatagtg ttcattcaat ttagaaatca
     7921 cagttggttc aataaaaacc gtcgttcttt tatttgattc atcgataatc gttccatcta
     7981 ttttattttt atagctggct ttgataggaa tcgtatagta ttcgcctttt tgaacaatca
     8041 ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa gaatttcagt aattttgact
     8101 ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt acgcaaatta cgtgacgcgt
     8161 cgtcactgac tttattattt tttattttct ggtcaatcaa ctcttctaca tttatcaaat
     8221 caggaagatg tttgctataa gcaaacaaca agggtgtctg gtattgattc ttatcaaaaa
     8281 actttgtgat catccgactg cttctaagaa aatccgcata ttcgatcaaa tcggttggct
     8341 gcagaatcaa cccttttttg acttgttctg tcagtgcatc gatcctcggc aaccccataa
     8401 atggaacatg ctgactgctt tctaagatca agcgtgcttc tcttgtttct tcttgacgat
     8461 ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct gattcgtttt ttgctatagt
     8521 ttccaattgc tcttgcttgg atttcctttt tgatccgatc aaattgtaat tgactaatca
     8581 tttcgttgtc catattctct ccttttcttg aagagatacc tgtcccaaaa taaataaggg
     8641 cctagagata aataaaagga tagaacacag cttaaaaaag tcatgtccta tccttattag
     8701 aatacaaaga tattgttttc ctgacaggta ccgtttcata agcacaccaa ataaactttg
     8761 tttattggct attcgactta ctgattagat accagctaca ctcacaaaac ataccccatt
     8821 cttctaggtc ttatttattt tccacttaac tatagcaaga cacattttgg ttgtcaaact
     8881 ttagtatgtt ttatagattt acaccattaa tgaatagaca cctaccgcga taattgctcc
     8941 gatcattgga cctgcgattg gtacccatga atatgcccaa tctgaagttc ctttattagc
     9001 tattggcaat accgcatgtg ctaatcgagg accaaagtcc cgagcagggt tgattgcata
     9061 tcctgttggc cctcctaatg aaagaccgat ggctaagatc aatccaccta cagcgaatac
     9121 gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc aacccaagaa ctaatacaaa
     9181 tgtaccaatt aattctgtga tcacatttgc tggataattc cgtatagcag gacctgttgc
     9241 aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc caatgtggca aataagaaag
     9301 ccaaacaaga atggcccctg caaaagctcc taaaacttgc gcaatgatga aaggaacgac
     9361 aagattccaa ctaattgccc ctgtcatcgc catagctaga gagactgcag gattcaaatg
     9421 agctgggccc atgaatccag aaatatagac agccattgtt acagcgagtc cccaaccaaa
     9481 tgcgatgaca atccagccag aagcctgtgc tttacttttg tttaaattca cagccgcaca
     9541 cacaccatct ccaagcaaaa ctaggatcag tgtcccaata aactccccca tgatttgagt
     9601 catatcactg ttcatttatt tctccccctt tagttcccgc agatctgatt ctgcaatcaa
     9661 tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct gtccattcaa aatatccagc
     9721 aattgcatcg atcacaggtt gcttgatctc atcaagctga tctcgttcaa acaacagatg
     9781 atttgtacga cgaatgagat aatcgcctgg ggccaaaacc atttcttctt ctaaaccata
     9841 acgtaaccga gctgactcag cgagactcaa accaggataa ggtgccattt cttttgctaa
     9901 ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg atataagtag catcttcttc
     9961 ctctaaaccg gctgctactc cttcttttgc taattctgtc actgtttctt ctaatttagt
    10021 tggatcgaag tttccacctg aaatctgata ttttttagag tcgatttctt tcgtctctat
    10081 tccgtattct tcttttaata attggcgtat caatcgcaaa gctccttctg ccatcttacg
    10141 gtaatcggtg attttcccac cagataaagt cagcaaacca tctggttctc tttctaaaga
    10201 actacctctg gaaatcgtag aaggtgcttt ttcatcacgg ctgttttcca aatggttcaa
    10261 cacgtcttct acttcagcac gagaaacttt gttttcctta tattcactta ctgtatcgac
    10321 aactttattg aagctcttgt ctgaaatcga tccattatct ccaccattgt aatcagaacc
    10381 agaattacca atcaacagtg gacgaagtcc tgcccagctt gcttcgatat cattcaatgt
    10441 gatatttgct tctggatagc gatgattgat cacatccaat agataatcta catcttcttg
    10501 tgtgactttc ggatccgtaa aatctccttg gtaatccgta tctgtcgtac caaagtaagt
    10561 cttgttttct cttggaatag caaaaaccat ccgcccatct tgctttcctg tatcgaagta
    10621 tgtgggttgc ggtacaggca gttttttcgc atctacaact aaatggatcc ctttagttgg
    10681 acgcatttta ggagagactg gacgcgtaaa attcaagttt cgtactttat ctacccaagg
    10741 accactcgta ttgatcacta attttgcttt gatttcgatc acttcatctg tcagcaggtc
    10801 acgagctttg acgccaacga tttgatcgcc atcatataaa aagccaaccg ctttcatttt
    10861 acttactaga taagccccat cttcggcagc ctttttgata ttatcaatca ctaaacgggc
    10921 atcattgttg cggaaatcta gatagacacc cgcgcctttt agcccttctt ttttcaaaaa
    10981 cggttctctt tccaatactt cttctggtgt cagcgtataa ttctcatatt tggttcctgt
    11041 cacatttgcc agtttgtcat aaaggtccat tgctactttg accgagaaca tattgaaggt
    11101 tgttgctcct tcgccctcat agattggcaa aagcattgga tctggttttg ggatgtgtgg
    11161 ggcaatactt tgtacgactg cacgttcacc aactgtgtca gctactactt ccacatcaaa
    11221 tgtcttcaga taacgaatac cgccatgaac aagtttggtc gagcgagagg aagtcccttc
    11281 tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct gatgctgctg actggactgc
    11341 cacaccggca ccagtgattc cgccaccgat gatcaacaga tccaattctt cttgctgcat
    11401 tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata tggatttcct ccttattcaa
    11461 atgcttgggt agcttttact gcttttttcc aaccgttgta aagtttttct cggcgctctt
    11521 cctccatttg aacttcaaat agcttgccag cttcataaaa ttcgcggatc tcgtctgtat
    11581 ctttccaata accgacagct aatcctgcta aaaatgctgc ccctagcgcc gttgtttcca
    11641 agttttctgc tcgttggatc ggtacattca agatatctgt ttggaattgc atcagatatt
    11701 cattgtttgc tgcaccgcca tctactttca atacaggaat cttgattcca gtgtcatctt
    11761 gcatcgtatc gatgatatct ctcacttgat aagcaatcga ctgtaaagta gctttaatga
    11821 tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc ccctcgtgct gcctgatccc
    11881 aataaggagc acctagccca acgaatgcag gaacaacata aacctcatct tcgcttgtag
    11941 agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa catttgaagt ccatctctca
    12001 gccattgaat cgaagaacca gccacaaaaa tacttccttc taaagcatag taaacctttc
    12061 catttatgcc gtaaccaatt gtcgtcaata aattattttt ggataattgc ggtttttcac
    12121 cggtattcat gacaataaat gaacctgtac cataagtatt cttgaccatg cctggttcga
    12181 atgccatttg tccgaataat gcggcttgct ggtctcctgc catccctgaa attggtgctt
    12241 cgcttccata aaaatgataa ccttgcgtat aaccataaac ttctgagtta gaagtgactt
    12301 ttggtaacat cactcgagga atatttagta aatctaaaat ctcctgatcc caatctagct
    12361 gatggatatt gaacaacatc gtccgactgg cattcgagta atcagtaaca tgtgcttgtc
    12421 catcggtcag tttccatact aaccaagaat cgatcgttcc aaacatcaat tcgccttttt
    12481 cagctcgttc ttgcgcgcct tctacatgat caagaatcca gcgtatcttc gttgctgaga
    12541 aataggcatc gatcactaac cctgtttttt cgtggaaaaa ttcttgatag ccttcatttt
    12601 ttaagttatc tgcaattcca gctgactgtc tggattgcca aacaactgca tgatagattg
    12661 gacgtcctgt atctttttcc catattactg ttgtttcacg ctggttcgtt atgccaatcc
    12721 cagcaatctg atttggtttg atccctgatt cgatgaacgc tccggcaata actgactgta
    12781 cagaattcca gatttcattt gcatcatgtt ccacccaact ttcttgcggg aaatattgcg
    12841 tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt gtcaaagata attgctcgtg
    12901 agctagttgt accttggtca atcgccatga tatacgttga ttctgtcatt gtgattccct
    12961 ccattatatg caaacgcttt ctttaactac tcttatcata ctactgtttt aaaaaaagaa
    13021 actgtcaaaa ttttattctt tttttctttt tttgacagtt ttttattatg aagctatttt
    13081 ttaatcaatt cttttctttt ttcagcgtct ctattcttct tttcaatcga ataatgtcgt
    13141 aaggtgacgc aaattctgac agataatatt cacactgttt tttgtttctc tggcaaaatg
    13201 tgatcaccaa atcatattct ttaccttctt cataacttcc aatctcaata ccgccgattc
    13261 ccctcagttc tctgatcaga tattgttgaa aagcaatacg ataaatcggc agactttcta
    13321 aatcgattcc aatcactact ggttttgcaa tataaaaatc gatcatcaaa agaacattgg
    13381 catactggat catcaggtaa ctaagctcac tatcttcagc tcttttcctc ggcaattgct
    13441 gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa ggaatgcccg agcattttct
    13501 gctgctgttc caaaagccga tcacgctcat agacttcgat ctttccaaca aagaaaaacc
    13561 attcattgtt gatctgggaa atttggtagc ctactgcctt ttcttctttg attttcaaac
    13621 gacgaggacg ataatgccat aacatcgttt cccgaatgta agtatctaaa acagcggttg
    13681 gtaacttttt gctccgtgtc aaatcatact gataaaatat ttcttcgtct actatcgaaa
    13741 aagaaacaaa aaagctgtaa aacatcattg tttcgtatac attcagttct gctgctgttc
    13801 gactaagatg catcacgatg attggatcga ttgcttgata aagccggtcc gactgataga
    13861 gtaatttctt ttctttcaaa gttgcgtacg tacttttttc attcaatagt ctttttttcg
    13921 taatcccgag ccagcaagca atctgtgctt ctgctgatgc cgtaaacgtt gtttctaata
    13981 cacggtccaa tcctagaatg aacggtcttt tttctggtgt attttgcaaa aaaagcggtc
    14041 gctgatcttc cgggatatat tggaatagtt cataataaaa atatcgtatc tgtagctctt
    14101 ctccgtataa ttgaccgttt ttgatttgta atccaaattc ctctaagagc tggttcaatt
    14161 ctttgatctt tcgaaaaaca gaagactcac tgatattaaa cgctgtcgct aatcgaacga
    14221 tggatacttg ctgatgttct aataaataga cgagcatctt aaacttcaag ctttcctgca
    14281 ataaaaacaa tagaattttt tccaaactta catcttcgtc caacacaagc agcgcctgat
    14341 actcatttcg ctgtacttct actttttttt ccatcattcg gccaatcaat tcaatatctt
    14401 ccaaatattg atcaaacgag gcttttgaca gttggacatg ctctctcaaa ccattgatag
    14461 aggctgttcc cccttgcaga acaaggtttc gcaaaatcag gatctgtaac tgctcttttc
    14521 tttctaataa tgcttcaatc ttcataggca gtattcgcca cctttgacca caccatatct
    14581 ggcacacggt attctggctg gaaaaatagc tcatgttctt ctaactgttc aaacgtccat
    14641 ccttctttta ctgcaattgt cagttggtca agaaggtgga acatctcttt tttgctttgg
    14701 agctgtgctc caagaatctt tttttcagaa tcaaatagaa atttgagttt aactttgctt
    14761 tgatttattg ctgtaagctt gtagtctacg tatcctgttt caattttttg gggataaaaa
    14821 atgctctctt cttctgtcaa acctacgctt cctaagaaat agccaaacca ctgattgccg
    14881 actggacgat aggttccctg atcctttgtc tgtgagccac taattgtctt gctgacattt
    14941 cgtgctgtac ggacagcgtt atttactaga gaaacataca ttttttcatt tgttggacga
    15001 aaagttactt ggatcgcatc gccaatcgca taaacgtctt tttgagacgt ttgcaagtag
    15061 tcatctaccc agatcgttcc atcatcattc aatgttaatt gttcttccca catctgattg
    15121 tcggggcgag aatgattagc cagcaaaaca agatcatagt tctcctttct tttttccgtc
    15181 tctacaatag cggtttcatt ttcggtcaaa gacacaactt gttcttctaa aaaaagtgaa
    15241 agcccttgat ttttcatttc ctttactaac ggttctgtca tttcaggatc tagataacga
    15301 aaaagaattg actttcggct ttcgtaaaga tggatttgtt tttttcttga tgccaaccct
    15361 tcagctattt cgattcctgc ttgtcctgca ccaataattg caattttctt tgcattcatg
    15421 atcttttgct gaagagccgt tacgttttgt atctttttaa ctgggtgaat aagcgttgat
    15481 tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg ctagaatcaa acgatcaaaa
    15541 tccaattttt ttcctcctgc taaaacgact tttttttctt tcaatcctat tactgtcttt
    15601 tctgtgtaaa catggattcg atagcggtca gtcagttctt ctttcgtgat ccaagaaagt
    15661 tgtttttcac tggtaacctt tccttttaat atcaaattga acccgctggg aatccatcct
    15721 aacttcgatt gcttttcaat caaatatatt tcacttgttg gcatcaattg gcgaagataa
    15781 atagccgcat gaatccctgc aaacgacccg ccgacaatta caatgttcat ctgcattcct
    15841 ctttcttata aggtgttcta ctgctaactt ctcaatcaga aaacacagta ttcataactc
    15901 gctttcaacc ttatgataca tagcgatgca gcagaatcaa ccctctccat cataccgtgt
    15961 tctaggtctg cttctcaata atgtactagt ggacctaatt gaagagtatc atttctgaag
    16021 agatgtttca aaaaatgtac tcttataaaa gaaaaaaact cgccttttac gtacctctgt
    16081 ccaaatagga aacagaaaag aacgaaaaga cgagttttag cgtgtgtaat gtaatagtta
    16141 gaatagacac atcatttatt tttaattctt taatgcttca acaactgctt cgcctaattg
    16201 atgagcagat tgaggatttt gccctgtaag aagccgccca tcaatttgaa ccacttctga
    16261 aaaagctgct ccagactgat agtttgctcc tttttctttc aaagcatctt ctgctaagaa
    16321 tggtacttca ttcgttgtac catttgcttc ctcttcttca ttactgaacc cagtcactgt
    16381 acgtccagct aaaatagatt ttccagactc atctgtaact ggcaacaatc ctacaacacc
    16441 gtgacaaaca gctgagacca gcccttcatt tcgatagatt tgtgaagcga ctttcccaag
    16501 atctattgct tctggaaaat cccacattgt tccgtggcca ccagcataat aaaccgctgc
    16561 ataatcattt gcatccacat catcaggacg taaggtattt cccaaggccc gatttctgaa
    16621 atcttcatct tcataatagg cccaatcgat ttcatccata ttcaaaacac tttgcggttc
    16681 taaaggtaca tatccgcctt taggactgac aaaatctgca tcgatcccat tttttactaa
    16741 tacatcataa aaatgagtca gttcacttaa ccacaaacct gtaggacgct cgatcttttc
    16801 gtacttttct acatttgtta atacgatcaa tactttcatt ttcccatcct ctttctataa
    16861 aaattgcgtt attgataacg tgctttcaag aaattatata atgggcttgg caaataaagc
    16921 tctttatatg cttcttcaaa aggtttcgtt acaaattcat cctcacggtt ttccaataat
    16981 ttctctgccc agtcaggatc gacgatcatt tgctgtccaa ttgctgcaag ttctgcatat
    17041 ttcaatacct gctctacatc ttcgcgattg cggatcccac cgacaccaac taaagggatc
    17101 tttccttgaa tcgtgttatg gaccacttca agaatcgatt tatcgttgta tttatcagaa
    17161 cgagctattc gatcatacat atttaatgaa acatgcagat aatctagttt tgactcacgt
    17221 aatcgttcaa gaagccagat cgtgtcttca aaacggatac ctggtgtttc atattcttct
    17281 ggtgagaaac gataccctac gatgaatggt tttttagcat attgttcaac cgctgagaaa
    17341 accgttgtta ataattcttc aataaaacga taacgatttt ccaagctacc gccccattga
    17401 tcctctcgtc tattcgaatg cggagagaaa aattgttgga tcaaatacgt atttgctcca
    17461 tgcaactcga ttccatcaaa tcctgattca atcgctctac gtgtggcttt gccaaatgct
    17521 tggattgttt caacgatttc ttcttcactc attgctcgtg gtgtttccgc atcaggacgt
    17581 tttgctgcaa ctgcacttgc agatacaggc tgttctccag ataaagttgc tcgacttgtc
    17641 attcgtccac cgtggaaaat ctgaataatc gcttttgcgc cttctccttg gattgctttc
    17701 gctagctcac ttaatcgagg aatcatttca tcatgagcga tgctgagttc acctggccag
    17761 ccttttccga tatcttggac atttgcagca ccagtaataa cagcaccaag acctttagaa
    17821 cgttgtttat aataagtgat ctcatcttcg gtgatcactc cattgaaaaa gctgagttgt
    17881 gtcgtcatag gcgacagcat caatcggttc ttcaattgaa ctcctgaagg taaagtaatt
    17941 gattgatcaa attgtgacat tgtcattcct cccataattc gctctgatta acctatcgag
    18001 aatcatctat cattaaacca ctcgattagt tgtacatgca actaatttgc ttaaaaaatt
    18061 ttattttttt tgtaacttat ctgttgcatc attcattgtc tgggctaatt ctttacttgc
    18121 ttcatttccc aaaactgctt tgtatgactg atgaagttct tcccagctac catcgacttc
    18181 cttagcaaat tggcgtcctt gttctgtaag ataaactaat gacaagcgac cttcgctaac
    18241 tgttttgacg tatcctttat attctaattt ttcaacaaaa cgagcaatcg ttgatggggc
    18301 ggaatagagc atttgtgcaa tatctttttg tggtattcca tctttttctt ttaatatcaa
    18361 taaaataaaa ccataagttg gtgccagacc tgtccttcta aacgcttcat cagctaattt
    18421 attcaacatg cgatctagct ttttcacgct aaagaaaaga cattcatcta acgctttttc
    18481 aattggcttt tccatttcat cccctccatt ggcgtacata tcatagtatg atttttattt
    18541 tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct agatttgaaa aaaagaagta
    18601 gccatcttca aagaatttcg gcttgttttc gacaaaactc cttctggaac accgtgaatc
    18661 agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa aaattttgtg aaaatggctt
    18721 tccacatttt tgcataaatt tggcttaata ccgaaaaact ggcttttgaa caccgtttat
    18781 atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa gaacagccaa acaaaaatag
    18841 ttcctcatat tttgtcgttt tttgagctaa tgccgatggt cagctgattg tacaccgttt
    18901 attgagaggt cgtgagcctg ccgttgaact ccgagtcaca aggagcaatt tcaaaaaaca
    18961 gcttctcatg ttttatgact atggtgactt gtgatcgagg agttggcagg agaatactgt
    19021 ttattcgtaa agaaggggct gtgacaagac ttttgtcaca gtcccttatt tccttttatt
    19081 ataggatttc gccatttgat tggatgactt gtctgtacca atcaaatgat tttttcttta
    19141 accgtttctt tgtgccattc ccttcgtcat cttgatcaac atagatatat ccataacgtt
    19201 ttgacatttg tgaagtagaa gcgctgacga tatcaatgca gccccacgac gtataaccaa
    19261 ataaatctac tccatcttcg atagcttcct tcatctgctc aatatgctgc ttcaaatagt
    19321 caatgcggta atcgtcttga acggttccat cttcttctac tttgtctata gctccgagtc
    19381 cgttttcagc tatgaacagt ggtttttgat acctatcata taattgattc aaagcaattc
    19441 tcaaaccctt aggatcaatc tgccagcccc attcacttga tggaagatac ggatttttaa
    19501 ttcctccagt tattaagttt ccttggaccc cttccaaatt ttctggatga gcactgactg
    19561 cactagacat gtagtagcta aaagaaacaa aatcaacagg gtaggctgct aagatttctt
    19621 catcacctac ttctattttt aagttgacac ctttttcttc aaacattcgt tgcgtatacg
    19681 ctggataata tcctcttgct tgaacatcac taaagaacaa agaagttctt tgctgctcaa
    19741 ttgttttttg aatatcatcc ggatcacaag aatacggaac aagaagctga tagctgatca
    19801 tacaaccgac ttgtgaacct ttgataattt catgacaagc ttttgtagct aaagcacttg
    19861 ctataaactg atggtgtgca ccttggtatt tcgcttgttc caaatgggga tggttttctt
    19921 caattactcc tacgctaaca aaagggtgat gttttacaca gttgatctca ttgaaagtca
    19981 tccaatattt tactttattt ttatagcgtt tgaatactgt ttcagcgaaa cgaacgtaaa
    20041 actgaataag ctttcgatta ggccatccac catattctgt aaccaaatat aacggcattt
    20101 cataatggga aagagaaacg actggctcaa tcccatattt tagacattcg tcaaacactt
    20161 gatcataaaa aaataatccc gcttcattgg gtgtttcttc atcaccatga ggaaaaattc
    20221 ttgtccatgc gatagacatc cgatagcatt taaaacccat ttcagcaaat aaacggatgt
    20281 cttctttaaa gtgatgatag aaatcatttc cgtgtctttt aggataataa tacttgctgt
    20341 tgggatcctg cgccgctttt acttgctgat gcgtcatcat atgccattga tctgtccatt
    20401 tttctttagg taaatcgctg tcgaatgtat acacatcaga cacagataat cctttttcat
    20461 ctacatccca tgcaccttca cattgattgg ccgctgtcgc tccgccccat aaaaatcctt
    20521 ctggaaattt tttcatatcg atccccctaa acttgctagt tttcttgttt gattattttt
    20581 cttatgacta gtaatgatat ttttgaatct actactattt gtaacaataa ccattgtggt
    20641 cggatcatat ccctctttga ttaattcttg caaatctact tccatcaata aatcgccttt
    20701 acgtactttt tttccatcag atactgcact ttgaaagtat ttgccattta aattcactgt
    20761 atcaataccg atatggatca gtatctctgc tccttcttca ctgactaccc caattgcatg
    20821 tttcgttgga aaaactgttg aaacttcccc gtttacagga ctgtagattt ttccgtccgt
    20881 tggaatgatc gcaaaccctt ctcctaaaga tccactagca aatgttggat cgtttacttc
    20941 agataaatca attatttcac ctgctgcagg agtacttaac actatatcct ttgaggattc
    21001 ttcttcgatt tcatccttgt agccgaaaag aaaagttagc atacaggaac tgatcatcgc
    21061 taagaaataa ctagcaacta gccaaacaaa tccttcacca atataaatcg ggaaagacaa
    21121 aatacttctt gtagcaactg ccaaagcacc ggctcctgcg gcaccagcta ctccaccaaa
    21181 tatagctcca catatacaag caatgtaaaa tggtcgttta tatttaagag tcacaccata
    21241 aacagcaggt tcagtgattc caaataatgc tgtgataaat gcagataaag ataaactttt
    21301 tactttctta tttttcgttt tcaaaaatac cccaagtact gctcctgctt gcgcagctac
    21361 ggcagtcata catgctggac ctagcgtatc acgaccgtag aaagaaagat tgttggtcat
    21421 tactggtaca agtccccaat gtaacccaaa aatcactaac acttgccaaa atccgccgat
    21481 aacagcacca gataaaacag ggctaaagtt ataaacagct aaatatccag ctgcaatcag
    21541 ctgacttgca taatctgcaa ttggacctac aactaataaa gtaattggga ccatcacgat
    21601 gatacaaatg aatggtgtca ataaatttcg aatactttcg tgcaagcttt tgcgaatctt
    21661 aggctcaata taagaaagaa cccatacagc taaaattgct ggaataaccg tacttgtata
    21721 tcttgctaga atcacgggca tccctagaaa tcgcaaggtt atgctatcac tatatgcact
    21781 gacaatcgta ggataaacga gagctgctgc aataaccata gcgatgaaac gatctgtatt
    21841 gaactttttt gcagcagtat atgccaaaaa tataggcaag aaatagaaaa atgcatcagc
    21901 tgctgcattc aaaatgatat aagttcctga ttcagtagtt aataaattca aactcgtaca
    21961 taaggcgagt actcctttga tcaaaccact tcctgccaag acgcctaaag tcggggcaaa
    22021 aacagcggcg atcatgtcta taaaagagtt taaaatgcct tttttctcag ttcctctctt
    22081 tccactagat gcatcatctt ctagtttcat ttgtttggat aatacgtcat acacttcatt
    22141 tactgcattt cctactacga cttgaaacat tcctccagct tcgactacag tgatcacacc
    22201 ttctagttgc tctaccttct ccttatctgc cttcttatta tcttttaggg taaagcgtaa
    22261 ccttgttgca caatggtaaa cattgctgac attttcttcg cctccgacaa atcggacaat
    22321 atctttcgct aattgtgaat agtccatttt tacttccccc ttgttaatta atgccgtagc
    22381 aatccttctt acaagataag tatagttctt agaaaacggt ttctccattc aattagtacc
    22441 ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg tttacttagc cgagcaaatc
    22501 actcactgct tgaaagaaaa caagtatatc gtttctctta tagtcaaagg agacaaaaaa
    22561 aacacgcttg atcttccttt gctgatgtat aagtggtatc tcaagctgat actctgtgat
    22621 ttttgtttct acttggcttt tgataagaca gcacaacaaa gtctcggcat ttaacggaag
    22681 cataactagg tcagaactag gagagattag ttgctgaatg gaatctatct ttttatggat
    22741 ttttatttga ttttcttctt tgtagtaatg atcaagcagt tttgttttct ttttttcttc
    22801 aactatggtc agcttttcac gcaaaatctg ataaatctcc gaagattcaa actcatctag
    22861 aacactaggt agataaatca aatcatccca ctcaaaaata agctcttgct cagtagtcaa
    22921 aattgcatca tattccgtta ttttgtttga ttgatttttg aaaagataca ctggttctat
    22981 ccggcattct ttgatccaca tgttcatact ttgttgaatc tgttttttta gtgtattcaa
    23041 aatactaatt ggctggttac taacaatcag tatctcccct tgttttcgaa aaggattcaa
    23101 cgcttcggca agatacaaaa ccaaataagc gctttcagct aaattgggac gtaattgaaa
    23161 atgtattggg aagaaacgcc gaattaaata aatttctaaa ggataacggg agatgatctt
    23221 ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc ctcgttttca tttgtttgat
    23281 atgggttagc aaaaattctg tttcatggaa caataacgaa acaggaagat ctaaaaaacg
    23341 aataatcgtt tgctcaaatg ctcttagatt cttctctatt tctttgtttt tttcatcatt
    23401 aatcatcaaa taatttaact ctaatagtcg attttcaatt gcttgttttt cttgattgga
    23461 aaaagaatag ggtagttctg atgataactt ttttgtgagg gtctctacca tcggaataaa
    23521 taatgtatac ctgtttgttt tttctaaaag ttcttctctt cgaagaatgg tcaaaacgag
    23581 ataccgagaa aatcgtatga agtcctctcc tgaaacaata taattatatg atataagaac
    23641 ctcttttaat gtcttttgga cagtcggcat gatattggaa aaaattgtac tgatttgttg
    23701 aggcaacctt gcgtgttgga tcaccgtttc tgttccaaca agagataaga aaattctttt
    23761 tgaattttct tcagcaatga tttttagtcc ttttgtcgac gaaacttcca gttctaattt
    23821 aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt aatgatacgg ctgtttttga
    23881 aagaaagaaa atgtctgcta tcttttgcat actgacatac cctttttgaa acaataagta
    23941 cgtcacaata gttgaagctc ggaaatccat gctggaatag attttatgtt tcgtcacctc
    24001 ttgtatgatt tgctgtttag tttcagattc aattgattct aaaaaataac ctgaacgttt
    24061 atttgactgg ataatgattt tcttctcgta gatagcaagc atatttttga tttcagtttg
    24121 gatcgttttc ttgttggtac ctaaagcttc agctaattct tcgcttgtta tccaatgatt
    24181 cttatttctt aatactacaa gaatttggag ttgtcgttta tttaagtcca tttgcttaca
    24241 cctcctcttt gttataaaca tacaggaaaa acctctcaaa tgacaatagt cacttgcaga
    24301 ggtttaaaaa tcatttgaag aaagatctat attcaaggtt tttaccatta gactggataa
    24361 tttgtttata atattcaaaa ctatcttttt tcaatctcct aaagcttccg ctcccatcat
    24421 tttgtctatc cacataaata aagccatatc gcttcctcat ttcccctgtt cctgccgata
    24481 cgatatcgat tggtccccac cataagtaac caatgatttg gcaaccatct tttattgcct
    24541 cagcaatttc ctgaagatgt atttttagat actcacaacg ttttggatcg tggattcgat
    24601 tcaattcatc tggtgcttca tctagtccaa tgccattttc aactatgaat aatggtaatt
    24661 cataacggtc tgtcaattca ttcatgacat aacgaaaccc tagaggatca attggccaac
    24721 tccaaggttc gggagatttt tccttcaaaa agggattatc gaaaccattt gctccgccag
    24781 tatctacgcg catttctgct tcttttttat agacagcgct acgataataa ctaaatgcaa
    24841 tataatctac cgtgttagct tgcaagtact gttcgtctcc atctaacatt actggtgcac
    24901 agtcttcttc cttccatatc ctgtaaatat aagctggata atgccctcgg cacatgacat
    24961 cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc aaatacattc tctggatcac
    25021 agtcatatgc ataagtcgct aatgcagaaa agctacacat aatacccatc ttagcatttg
    25081 gatcgatttt ctttaataat tgagtagcac gggcgttcgc tagaaacata tgatgacagg
    25141 cttgataaat ctcttttttt gttagtgtag caatgggttc aagtttatct ctagcaggga
    25201 atgtaaccaa tccagcagct gcataaggca tacgaaaagc attattgatc tcattaaagg
    25261 tcatccaata tttcactttc ccttggtagc gttcaaagac ggtctgcgca taaaattcaa
    25321 aaaagtcgat taattttcga ttttgccacc ccccatactc tcctaccaat gctaaggggg
    25381 tttcataatg actaagagta attactggct cgatatcata tcgatttaat gtattgatta
    25441 gtctgtcata aaatacgaga ccagcctcat ttggcttctg ttcgtctcct cttggaaata
    25501 ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc taactccttc agtaaacgaa
    25561 tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg agaaagataa tggagtgatt
    25621 cgtctaaagc aatctcccaa atcttttttt cttcattcca ctgaatacta ggatgctggt
    25681 tcatgatccc gataagcgta tctgtcacat taggtaattt gccgtcttcc aaccatgcac
    25741 cttcacattg attagcagct actgctccgc cccataaaaa attttctgga aatatttcct
    25801 gatccataac tatctctcct cgctatcaac aatttcttac ttgaagtata gctcgattca
    25861 tcaaaacaag atattctaac tatttcggca gaagagaaga aaaaaattga atgctactct
    25921 tcatttttaa tatttatata taacaaatac ataagacgat ccccgaaaga aaacactcgt
    25981 taaccatcta agcaaacgat ttattttact tccaacacaa atgcttcata aggtcgtaaa
    26041 tcaactttgc cgtctggtaa ctgtttcaga ggataatttg acacaataac ccttaaagct
    26101 tcacgtggaa cagtgaacgt ctgcttttca ctggacatat tacaaataac gagccattgc
    26161 tggtcttcat atatgcgaga ataggcaaag acatgctcag gcgtcttttc cactaattca
    26221 tagtctcccc agacgatgat gtcatgtttt ctacgcaaat cgatcaattt cttgtacata
    26281 taaaaaacag aatcttgatc tgctaacgct tcttctgcat tgatttcttt ataatttgga
    26341 ttgactcgaa gccatggaat tccagtagta aacccagcat gttcacgggc gttccattgc
    26401 ataggcgtcc tagcattgtc tcttcctttc gcattgattg attccaagat ttcctctttt
    26461 gtaaatccag aagaaatcct ttcgttatac atattgattg tctcaatatc ttttgcttcc
    26521 gcgatatcat cgattgggca attcgtcatg cctaactctt ctccttgata gatataaggg
    26581 gtgcctttca tcatatggag caagatagca aacatcttgg cactttcttt tcgatacaca
    26641 tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt gattattcca aaataaacta
    26701 ttccatcctt catcacctaa agatgtttgc catttggata atactttttt cagttcagag
    26761 atactcaagg gtttcaaatc ccatttgtct ttgccttctt gctgatctaa tcctatgtgt
    26821 tcgaattgga agaccatgga taattcattt cttttaggat tggaataaag tttagcgatt
    26881 tcggtagttg ctccccatgt ttcgccaaca gtcatcagat ttttgtcacc aaaagttgct
    26941 tgattcattt cctgaagata ctcatgcagt ttaggtccat tacttgtgat ttctttatcc
    27001 ggttctttgc caatcatatc gatcacgtcc atacgaaagc caccaatacc tttatcgatc
    27061 cagaaattca tcatttgata aatctcttgg cgaacctgtt tatttttcca attcaaatca
    27121 ggttgacgct tgctatacaa gtgcagaaaa tattgccccg ttttttcatc caactgccaa
    27181 gcagaaccac tgaatattga gcgcaatcta ttaggctctt ttccattgac cggatcacgc
    27241 caaatataat agtcccgata aggattttct ttatttttac gggcctcaat gaaccacgga
    27301 tgttcatcag aagtatgatt caccaccaga tccatgatga tacggatatt tcttttcttt
    27361 gcttcttcaa tcagttcttc catttcttcc atcgtaccga attctgccat gattgcttga
    27421 taattactga tatcataccc attgtcatca ttcggagact cgtatactgg agaaagccaa
    27481 attgcatcaa tacctaaata cgccagataa tccaacctgg aaataatccc ccgcaaatct
    27541 ccaataccat cttgatttga atcttgaaaa cttcttggat agatttgata aacaactgaa
    27601 tggtgccacc atttttgttc catgattttc ctcctataaa tggatgtttc tattttttgc
    27661 ttaatcattt attttagtct ctctcactaa aaattgtaac gctttcaaat agctattgca
    27721 ccttgttatc ggtaacagaa taaaacaaaa aaacagctga ggaaattccc tcaactgttt
    27781 tttgaaagga ttgatttatt cagggaagaa tgctgatttc acaacttctt tataaacggt
    27841 gttcactcag ctgtccctcg gtattagctc aaaaaacggc aaaatataag aaactatttt
    27901 tttcgttttt ttctctaata ctcaggccag aacactgatt tcacaacctc tttataaacg
    27961 gtgttcactc agctgtccct tggtattagc tcaaaaaaag gcaaaatatg aggaactatt
    28021 ttttcgtttt tttctctaat actcaggcca gaacactgat ttcacaacct ctttatttca
    28081 cattcaatat ccacatgaat cccatgaata caaagaacag accatacatg atgggagata
    28141 cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa cctaatgcaa
    28201 tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat gaagggatcg
    28261 caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat actcctacca
    28321 taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga gaaaagaaca
    28381 agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt cctccaacgg
    28441 cgataccagc tgatgattct acaaatgcac caacaggaga agtacctaat aaggaacccg
    28501 caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc ttgttgtctt
    28561 tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca aagaaagtca
    28621 caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc cctacatgtt
    28681 ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt tcagaaggca
    28741 ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg atgaagatgc
    28801 cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa atcgtcaacc
    28861 aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc gaaacgatga
    28921 tcccaccttc gctcagacca aggaaagcaa taaatagacc gataccgcca gaaatcgcat
    28981 atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag attgtgatca
    29041 aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat ggaatcccca
    29101 ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt gccgttccaa
    29161 ttggataacg ggctaatacc cccattaaaa tacagccgat cgcactggct aatgcagtcg
    29221 cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga tttacaaata
    29281 agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt tttaccgtgg
    29341 tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc catcccccta
    29401 aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa acaacgtgtt
    29461 ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa gcaaaatccg
    29521 aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac tttggattac
    29581 aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa tcaatagtgt
    29641 gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt atcgacagga
    29701 ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc ttttgtcttc
    29761 ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc tcgccgatac
    29821 ttcaaataac cttctaatct tcccattaga tccactgttt ctcctccttt ttattcaatc
    29881 agacgactca gcttttccta taacaaaata attgccttca gggtccgaaa aattgaaagt
    29941 caagacgcca ttgttgtctg tgatttctcc tggttcttcc atgttctcgt agatagtttc
    30001 aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg gtgaaaactt
    30061 ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc tgagtacaat
    30121 actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa ttttttctac
    30181 aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg ttttttgtat
    30241 catcgtttga cccttctttc tatttgattt tctttcctgt ctataaactg attccattat
    30301 atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa gcaatagttt
    30361 ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat gaatgccgct
    30421 cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta gtgtgtgtct
    30481 aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga ttgcctgtgc
    30541 gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg cttgtgtttc
    30601 ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga tcgctccttg
    30661 ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg cacctaaagg
    30721 caggaatgat tcgtcacctt gggcttttcc taaatgcaga tttcctgcga tcttttcgat
    30781 atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga tatctacaag
    30841 cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag cttcaataga
    30901 agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact gagcaatgac
    30961 ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg ctgcctcatt
    31021 caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga taccatttac
    31081 ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat ccactattac
    31141 ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag atagtctgtt
    31201 tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc ttttttacga
    31261 taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc tgttttttgc
    31321 ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc ttgatgttta
    31381 aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat ttcctcagat
    31441 tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat actcactagg
    31501 aaaaaatctg tttctttatc ttttagctct tctgtaagtt tttctagtgc ataagcttgt
    31561 gtcaagtaat cagctaaatg ctccggtaat tatcttttcc aaatgtatct gtaaatgttt
    31621 cgatactaat ttgttgtagt aagtctacat ctgaaggcgt catttttcga atttcgtatt
    31681 tattcacggc ttcttccttt caatagatcc ttttattgcc ttttttgaca aaattccaat
    31741 cttcgctaac attcttgcat actttattta aaagatattc caattgtttt gcttcttcgt
    31801 cagaaagacc atttaatgcg actgcattgg agtagttgtt ttctcgaatg atgaaaggat
    31861 agatttctgc tcctttttta gtcggataga gtttcttgat ttttttattt tctttatctt
    31921 ccaaacgttc gatcatccca ttggattcta atttcttgat tgctcgggca gtcgttgtac
    31981 gatctacttt gatcatttct gctagttttt cttggatgat tccaggattt tcgcaaatac
    32041 gtactaaata aagatactgt cctcttgtta aatcgacttc tttgaattcg atattgctaa
    32101 tagagtctag cgctcgggca atcattccga tgtctcgaag gatttcagcc atttcatccc
    32161 acctttattt tgtttgtaag actagtttac ctctttttgt tgcaaatgca actattttta
    32221 ataaaaaaat caagttcttt tttaataact agtaaagtat attcttttct tcttttacga
    32281 aaaagctcaa tcacaataga tctggttttt gttttctaaa ataagtaact gtttcttcgt
    32341 tgttcgcttt tctgatagct ttggcaactc ttctatacta aaaaatccca tgttggaagt
    32401 ttcattattc tcaataaact tggcctcttc accgtggatc gcacaagcaa aaacaagttt
    32461 ataatactga aaaagctgtg gaatatcttt ttgtttattc gtatcaaaaa ctgctcgcaa
    32521 ctgagtagtt tctactgtta atcctgtttc ttcatagact tctttacgca cattttcttc
    32581 aggagacaat cctatttcag caaatccacc aggaagtgac cattctttcg tccgtttatc
    32641 ttcgattagt aggaccttgc catctttttt gatataggca cgaacatcta cttttggtgt
    32701 tggatgtcct tctccaatcg ttgtgagcgc ttttatttct tcgaaagttt cttttcctat
    32761 ttcactgatc agttccaatg aaatcgtccg gatctcctca aaacgctctt tatcaaatac
    32821 atcttttcca taatatagac cagcttgaga aagtgcgagt agtcttttgt attgagccaa
    32881 cttcttgttc attctcttcc cttctttttt agcaaatgta tgactatgta atcaagtata
    32941 gaagactggt ttaattacgg caaataaata taatgaaatc tgcaataaat aaaagaatgt
    33001 taaaaaactc gagaacaaaa gacattcgac ttctctgggg ctgtgaataa atggcgttca
    33061 aaagcttgca tctgcggtaa taagccccat caaacgaaaa atatgacgag ctattcttgt
    33121 ctggctgttc ttattaattg aggcaggaca gctttttcac aacctcccca ctaaacggtg
    33181 ttctcctacc aactcctcgg tcacaagtca caatattcat caaacatgag aagctgtttc
    33241 tttgaaattg ctccttgtga ctcggagctg aacgacaggc tcacgacctc tcggtaaacg
    33301 gtgttcaaaa gccaattttt cgatattaag ccatttcttt gttacttatt gtcattgatt
    33361 tctttttcta atttatccaa tagtggagtg taatccactt gagtatagtc tgttacatca
    33421 aattcatata gtgttcctaa ctggaatttg tcatattttc ggtcggcgat gatctttttg
    33481 aatgcttctt tcgtaatatg attggtccct ttcgttcgat cttccaatac gtcaccatag
    33541 tgataatgat ccatgatata gctcaaatga cgatctgatt cacgatcacg tttgtaccga
    33601 cgttgccata acacttcaaa gtctgctgtt aggcgaatcg tgatcacctg atatccgtat
    33661 ctatctgcta attcttggag tcgtgctttt tgcttatcac taaaaggata ctcggacaca
    33721 atcactttct ttcctgcttc catatacaaa tcaagtgctt tgtaatagaa aggataaact
    33781 ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa acccgatgga ttctgcatag
    33841 tattccttga tttcatcgag cgtgatggca tacatatctg gaaatcgttc ccgtagttta
    33901 ttcataagat atgtttttcc tgtaccagga ctaccagcca gaagaatgaa atactttttc
    33961 atctcattta tttcctaagt taattggact ttccaagttc ataaacagtc caatcttatg
    34021 cttgacaatt tcttttactg cttcatttgc tggaatcaca ttatggcgaa gagacttgtt
    34081 gatttctgtt tcactaaagg tttctttagc tactttcgtc cagttgacta aaagctccgt
    34141 tccaacattg aatttgcgga tcccgttatt gatcaattca ggataatctt cttctttcac
    34201 acctgttcct ccatggataa ctagggggac atcaactact gcatcgattt ctttcagcaa
    34261 gggaatgttt acttctgttt ttgatttgaa ttgtccatga ttcgtaccga tagcaatagc
    34321 taatgcatcc acgcctgtag cttctacaaa tttcactgcg tcttccggtc ttgtatatac
    34381 cttgtcattt tcagcgacat ggattccttc ttctgtaccg ccgattgttc caagttctcc
    34441 ttctacggaa acaccgtgcg catgggcata ttctactact gcttttgtct tcaggatatt
    34501 ttctttgaaa ggcagatggg acccatcata catgacagaa gtatatccgc tgtcgattgc
    34561 ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgc aagactgcat caaccatttc
    34621 ttcttctgca atagctgtca ttacattgac taacacatgc atgccgatat atttagcggt
    34681 atcgacactt gtttgaataa tgatcggcga acccatttct tttgctgcgc ctagcatagc
    34741 aggaagcatt tctaggttat gcgtattaaa agctccaact gtaaaattca actcttctgc
    34801 tgtttttgtt acttctttca atgttgtata catcttttat tgccacctta tctttttatt
    34861 tgtttccttt gatcgttact tgttttgcaa tttgtcgcat ctcatccatt ttgcccatgt
    34921 agtaatcgat cccttgatca tcaccagcac gagcagcatc tgcacgcttc tggttataga
    34981 ggctcatcag ttttttatac ccatctccga tcgtctgttt attttccaaa ctcttttcta
    35041 aatattggat ggcttgatcg ttcacataca attcagaaaa tttaagtcca acttgttcat
    35101 aaagtttcgc taatttatgc ttatcttggg tagtggaaat ctcttgtttc aattgtgtaa
    35161 tctctgattg aatcttttcg gtcgcttctg gcgatagggc tttttcttct tttgccagaa
    35221 cttttttcgg ttctttttct tttttcttaa aaaatccaaa catcattttc cctactttca
    35281 attaaaatgc tttcaaaact gggcttaaga tccaggcata taagagtgct gcggctactg
    35341 tatctacatc ggttgctgta gcattgatga atcccatcga attaaagatc gttactagca
    35401 aagcgggcaa taatgtaata aagaaaccat gagcaatacc gccaatgatc gctcctcggc
    35461 gtccgccaac tgcgttgcca aatatccctg ctgtccctcc ggcaaagaaa ttggttagca
    35521 taccaggtaa aatcatcgct aagccgaaca tgggcaaagt aaacatggca ataatcgtac
    35581 caatcgttgt cgtaatgaaa cctaaaatga cagcatttgg gctataagga aagaaaactg
    35641 gacaatctaa ggcagggatc gcatcaggaa ctaatttcat agctatccct cgaaatgccg
    35701 gcacgatttc acctaacagt agacgtacac cagctagcaa tacatacaca cccactacga
    35761 attggatggc ttgtaaaaag gcaaacatga tatagttttg atctcctgat aattcagaag
    35821 cgaatggttc gcctgcaaat aaaacagtga tgatatatag cgggaccatc acgaccatga
    35881 cagacaaata agtatcttgc agaaattcga aatgtgtcgg caacttgata tcttcgatcg
    35941 actttttatt ttcgcctttc tcaccaaaaa gcttagcaac accggcttca aataagtacc
    36001 cgatcgtaca aaaatgacct aaagcaatat catttgatcc agtgatttta cgaatgatcg
    36061 gttgcgctac tgccggcata gcaatggcga aacaagctcc gataaaacca ccgaccaaga
    36121 tcaatacgat ccctcgcaga ccggcaaaat agccaaagac tgtcgtcatc gttgccatcc
    36181 ataaaattgc ttgaccagtt aaaaaaatgt acttccattt tgtgaaacga gccaaaataa
    36241 tattgaatac aaaaatggct aagaacgtca gtgcaatatc tctacctaaa cccaaatcat
    36301 tcattgcttg accattgata gattcaatag aagggatgat cccttgcata tgaaatcctt
    36361 cagtaaagat tttcccgaaa taagttaaac ttccaacgat gatgctcgaa ccggcactca
    36421 acacttgaaa tcctaggagt gtctttaacg tgccagagat gacttgtcct gctgatttct
    36481 tctgcagtag tagacccaac atagcaatca atgcaatggt gatcgatgcc tgagtcaaaa
    36541 tattttcgat gataaaattg ataacgccca tgtttttacc ctcttttctt tttgtattta
    36601 gataactccc ttatcttgca gaactggggt gattttttct tcaatttcat tttttgaaac
    36661 aatatttttc aaatagatca tcgccgtttt aggatcaact gcgaactttt cgaactgcga
    36721 acgaaaattt tctgctgtga tgatcacatc tggtttcatg gaaactgcgg aagaaatatc
    36781 acaatggtcc agtttggctt ctactcctaa tttgttcaaa acatcctcag cagacatctg
    36841 tgctgcaaaa ctacttccta aacctgcgcc gcatacgaat aaaatgttca atttgttcat
    36901 ctttgttctc ccccgtatca tttattattt ctcaactact gaaaaaagca gttgtttgaa
    36961 atcttcgata tttgtgcatt caatcaatcg atccaacttc tcttcgttgt tgatcaattc
    37021 aattagttct ttcatgatgt tcagatggga gtaggagtct actgctgcca aacaaaaaat
    37081 aatctttact ggatccattt caggattacc gaaatcgatt ggttgctcaa tcgtagctac
    37141 gctgactcct aatttattga ccccatcttc tggtcgggca tgggctagtg ccatgtgttt
    37201 gccaatcacg atatacggtc cgtaatcatt cactgcacga atcatcgctt cgacatagcg
    37261 ctcttcgaca atgttttctt taaccaatgg tctagcagct agttcaatcg attcctccca
    37321 agtagtggct ttttctttga tcatgatatt gctgtccgtc aaaatatctt ttaacatagg
    37381 ctggatctcc cttttgttga tttctaaatt gtttgtttcg aataattttt ctaacttgcc
    37441 atagatgatt cgatctactc ggccaccact ttctttcatg acatctatta tttgagtgaa
    37501 taactccgtc gattcatgac tgttaggctc taaccgctgt agttcttcat ttcttttcaa
    37561 aaagtcttct ataaccaaga tattcgtctc agttaaaatc ggatcgacaa ctaaaagcgg
    37621 cttatttcga taattcaatt gaaaggtgct gaaaaccaga ttgacatcca atttatctac
    37681 taattcgatt tcttttgaac ttaaaactgc agtaatctcg atctgaggaa acttttcttt
    37741 cagattctct gctaacagat ttccagtagc catcccatgg ttacagacaa cgactgattt
    37801 ataaacataa ttcaagtctc gcttgattac actggcgatc gtcgaaaagt ggatgacaag
    37861 aaaagctatc tcgtcctcca gtatcttgcc accaattact tcttcgatcg taggaacaaa
    37921 atgagtgact gcgcggtaga ttgggaaata atttgttcgg atgttttctt tcaatggatt
    37981 catgacttgg atatgattct tgattcttac aatcagtgca gccatgtgct tatagagatt
    38041 ttcgaataag gcttcttcct ttagatggaa aggtacgtgt gtctcgttct ctacaaattg
    38101 gatcaattgg atcgttagta attgagcttg tacccactcg attgaattgg agatatctct
    38161 agcattgaac gtctcaatag tgaaacgaag ataatttctt tctacttgcg ggacattgtc
    38221 caattgaaat tcctcgatca tgtggtcaat aaatgcagaa aagctactgt cttttatttc
    38281 tgtatttttc caattaatgg cagagataaa ttcatgtttc ctgattcgct ggatccagat
    38341 caatgtaaaa agcaggattt gttttttata aatatcatct tcttgtttca acaacttatt
    38401 ggaatagatc tcctgtattt ttttgatttc ctccaaagga aaataatgga gaaagatttt
    38461 ttgagccggt gttaattgtg catcttgatt cataaagaag tcggtcattc ccagattctg
    38521 attgataaaa tcatagatca tcgtacggat agatcgttct gaacctttat aaaccagtcc
    38581 ttgctttcca taactgacga tctctatccc ataactgacc agtgttgctc gtaaccgtct
    38641 catatcttca tctaatgtac ttttagagat ttgaaattct tcttcttttt tgtttagatg
    38701 gatcgggatt cggctgtaag caacggctaa aactagatca aaaatacgtt cgcgccgatt
    38761 caaaaagccg tctttcacat cttttatttc agtttctaat cgagcttgct tttccttttc
    38821 cagcttcaac aaaaaacctt tgttgcgaat tgtacggatc tccggaagct ttttactgct
    38881 caaccagata ttcgcttcaa gaacttcctg acgaatcgtc cgctgactga cattgaactc
    38941 acttgctaga tgttttgctt ttactggata ttgggctgtc atgattctgt gaagtatttc
    39001 aattgttctt gttttcatag aaatgatctc cttctgattt caagtatatg gttccgctta
    39061 cataataaaa agtagatatt tctgccactt gaagtggaaa gaaagtaagc aaagcaaaca
    39121 aaaaataagc catatgcttt ttcatctcct caacgaaaaa gacatacgcc tattattaca
    39181 aaaattttgc ccatctatac aaaaaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
    39241 aagaacaact aaactaaaat agtgcttcct attttttgtt tggttgttct tattatcgca
    39301 gatgcaagct tttaaacacc atttagtgga gaagctgtga cagagatgtt cagccttgag
    39361 cgataagaag cgattttgaa aaatcgcttc ccatatttta caaaatcgtg ccttattgcc
    39421 gataggctat ctctggaaca ccgtttattc agaaaaagga gctgcgacaa ggcttttgtc
    39481 acaactccgt tcataaatat ttcctgtcaa tccagcataa tcggttgaat aaaatcggct
    39541 tgccatcttt tttctttctc agaaaaatca aaataccata tctgagaaaa atactgtcgt
    39601 tgtgtcttac ttcctgagat caatcgccca tcttttcgat cgactgaata atcacagcat
    39661 ctgaaatcaa ttcggatggc aaaactattt tcgtggatct gtcgataatt tcctacttcc
    39721 tgaatagtta tttttttagt atgatttctt acaccgtctg ctttgttttt ttgcagaact
    39781 ttctgatgtt cggcaaacag cttgtctgta taacagcttc tggctttttc aggagtttct
    39841 tcttcccaag cggattggat cttcatgaat atcttttgga tttccaaaaa ctgtgctttc
    39901 ttttctttag ccgttcctga catgcgggac aatatctccg atttcagcct tttcttttgt
    39961 cttttattct tgacgataga aaaagcagaa acccctccta ctgacaaaac agctaatgca
    40021 agaaaccccg tttgctcata actagaagga cctgtacttg gaccataata cccataagaa
    40081 tctctgccgt aagaacgact gccaaaataa ctgcccccat atgaacgacc gccaaatgaa
    40141 cctctgcccg aacttcgacc gctagatgta cctccaccat gaccacccgc gacagcgaat
    40201 ccttgggtcg gcagagcaaa caaacatagg cccactaaca aaatgattgc taaataattg
    40261 attttttcat tgtcttcctc gttatctttt attacaaaaa actattttta tcatagcctt
    40321 gctaaaagga agagtcaata accagatgca taaactgttt ttttagcaat tttgtcttat
    40381 ttagtcattg agtaacatcg gacagatgta tgtgtcggca gtccataatt cctctatctt
    40441 cagcatgaac aagcttgcag acaagagatc tgcgcttcct ccaggagaga tttggttttc
    40501 ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt aaagcacttt gactagcagc
    40561 atgagcaagt ttttgcattt ccactaacgt tttctgatca ctgcgatgca atacgcatgt
    40621 gtcatctagc gaactcatca aaactaacaa catatgcatt tgtttctgta catatgaatc
    40681 attatctagc tccttagctg cttggattgc aagcctgata tgcggatacc ctaatatcgc
    40741 ttcttcatat gcaccattta cgccatattt ttgcttcacc ctatgaccat gagtggtttt
    40801 tttatgacga tattttgtat caggaaaagc agcaagcttg ctgacatcat caagtatttt
    40861 cgataaagaa aaaggctgtt ccatactgat tttttgtgca atgacactga tcaatagccc
    40921 cattgcccaa atcgctcctt tatgggtatt gatgccattt gtagcaatca gcattgcctt
    40981 ttccgctttt cgcccaatct cagcaattct ttctcttaac tcctgatcaa tagcataatg
    41041 ccatgctatt tgagccattt cttcaaaaaa aggagttagc gtcttagcag acttatccaa
    41101 aatgcgccga ccttctttta cggcttttgc gatcgtatgg aaattatcat ctcctaaaac
    41161 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcga ttcctatatc
    41221 ggctcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    41281 atttttctgc aaagctttca cgattcgcag tttgtgttct ggtgtcgttc gagcaaagac
    41341 gtcgactttt ggtacttgtc gaatcaactc ttcttcagac ataagatcca aatcgatccc
    41401 ttctaaaact ttagcagtat gttttaagcc aatttgttcc gcgatcgctt ttgctgtatc
    41461 tttgtgatcc cccgtaatca ttttcactga gattcctgct tgttggcatt cctttacagc
    41521 tttgactgca ctttcttttg gcggatcaat caacccagca atccctgcaa aagttaattg
    41581 ggttaaagac tcatgcgtga gttcctgttt cgaatctact tttttgtaag caaatcctaa
    41641 aacacgctga ccttttttcg caaacgctgt ggctgtttga ccccatgctt cttattctga
    41701 agaagaaaga gttgatttag ccaataatac ttctggcgca cctttgacgt aaatcacccc
    41761 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagagctga acggaatttt
    41821 tgcttctatt tttttcaaag gcagatcggc tgtttcggtg tggcgaatca gtgcaagttc
    41881 tgtcggattg ccacttaaat tttctgtttt ctgttcttct ttcgtcttta attcctgaca
    41941 atttttcata ataaacagta cgcgagtttc ttcctttgct gctacatcca caactgtcat
    42001 ttcatttttt gtcaatgtcc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    42061 ttctacagaa ggcagtcctt tgatgatcgc cttttctttt gccatttcat gtactccgac
    42121 agataggatc atggtcaaca cagctggcaa tccttcgggt accattgaca ccaccaaagc
    42181 gatcatagct gaaagaagga tatgccaatc catgccatag cggaatgttg taaaaacaac
    42241 taagaacaag atcaaacaaa gaatgccttg aaaaatttgt ttgttcaatc ggttgatctt
    42301 cttgatcaga ggcgtcgttt gttgttcgac cgattgcagt gcttgattga ttttaccgat
    42361 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    42421 tcctgaaaaa gccatatttt tttggtcacc gattgattct tctgctgcca aaacggaatg
    42481 atttttttca gatgcttctg attctcccgt caaaatcgat tcttctacta gtagatcatg
    42541 tacttcgatc aaccgaacat ctgctggaac gacgtctccg gcacgtaaga caatgacatc
    42601 tccttttact agttctttcg cagggatttt ttcttgcatc ccgttcgata gtactatcgc
    42661 ttcttgtccc atcagctgct tcaaaccatt caacgattct tctgcttttc tttcttgcca
    42721 ataactaacg agtccgttga cgatcactac gaataaaata atacttcctt cgatgtattc
    42781 gctcgaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    42841 gtgttttgct atttttttcc atcgttttgt ctgctgtctt gcttctatct cattatatcc
    42901 ttgatcagtc aggcgtttct gccgttcttc ttgcgacaag ccttctgttg atgtttgata
    42961 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    43021 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    43081 tctgaaataa ttcgttttgc agaatgtatc tgggcctaac tgatatttct attgcttatt
    43141 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    43201 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    43261 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    43321 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    43381 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cgacaaaaaa taacatccct
    43441 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    43501 aaacttttct cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    43561 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gctttggcaa
    43621 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    43681 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agaggatacg ccaaggcaga
    43741 cagttgattg catttttcaa attcttttgt gggtcactcg tctcaccaac tgttaatccg
    43801 atcatttcaa ttccagcaaa actgaataaa accataggaa atgaagcaat cattccagca
    43861 aagccaaacg ggactaattc attgagctgt ccaaaatttg ctttgattcc aatagactgg
    43921 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    43981 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    44041 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    44101 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    44161 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    44221 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatgac ccgcatcaaa
    44281 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    44341 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    44401 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    44461 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    44521 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    44581 tgtcccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    44641 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    44701 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    44761 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    44821 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    44881 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    44941 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    45001 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    45061 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    45121 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    45181 tactccgcga atatacgttt taactggatt tttcaaccga gtgatataca cagaggacat
    45241 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    45301 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    45361 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    45421 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    45481 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    45541 cacattatcg ataatattac caaacaacgg agcaagtgct gaagcgacca tcaccatccc
    45601 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    45661 attcgatacc caaagttctg gaccaccttt ttggggaaac attccggcaa attcaccaga
    45721 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    45781 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    45841 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    45901 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    45961 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    46021 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    46081 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    46141 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    46201 ggatgatttc gtttagtttc ttttccattg ctttggcgat ttcttttgta taaaaattga
    46261 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    46321 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    46381 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    46441 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    46501 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    46561 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    46621 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    46681 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    46741 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    46801 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    46861 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    46921 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    46981 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    47041 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    47101 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    47161 ttcctacgac agcaaccaca cctagaattg ggattttttg ttcagctaat tcacgaattg
    47221 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    47281 gatctaagcc tactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    47341 gcaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    47401 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    47461 aattcaaaag ttcccactca gacatttttt tcacttgttc aggcagcact tccttgacag
    47521 ctaaaggaat cgatttgatg cagcgggcgt accataatcc ttcaagatta gcaatagaac
    47581 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    47641 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    47701 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    47761 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    47821 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    47881 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    47941 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    48001 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    48061 tgtctcgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    48121 aatttttttt ataacatcaa atccacgtag atttttacaa cgcgaattgt aaaattaagt
    48181 tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa
    48241 aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga caatgataga
    48301 atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg gacgtgctat
    48361 acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc ttgattattg
    48421 gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat tacctgctca
    48481 tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg tcattatcgg
    48541 gcg
//
LOCUS       DASHXG010000017        48481 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.017, whole genome shotgun sequence.
ACCESSION   DASHXG010000017 DASHXG010000000
VERSION     DASHXG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.017"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(29..376)
                     /gene="rbfA"
                     /locus_tag="U2R59_001098"
     CDS             complement(29..376)
                     /gene="rbfA"
                     /locus_tag="U2R59_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEM8965505.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(403..2709)
                     /gene="infB"
                     /locus_tag="U2R59_001099"
     CDS             complement(403..2709)
                     /gene="infB"
                     /locus_tag="U2R59_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEM8965506.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(2722..3033)
                     /locus_tag="U2R59_001100"
     CDS             complement(2722..3033)
                     /locus_tag="U2R59_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEM8965507.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(3030..3323)
                     /locus_tag="U2R59_001101"
     CDS             complement(3030..3323)
                     /locus_tag="U2R59_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEM8965508.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(3345..4520)
                     /gene="nusA"
                     /locus_tag="U2R59_001102"
     CDS             complement(3345..4520)
                     /gene="nusA"
                     /locus_tag="U2R59_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEM8965509.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(4543..5016)
                     /gene="rimP"
                     /locus_tag="U2R59_001103"
     CDS             complement(4543..5016)
                     /gene="rimP"
                     /locus_tag="U2R59_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEM8965510.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(5161..9519)
                     /locus_tag="U2R59_001104"
     CDS             complement(5161..9519)
                     /locus_tag="U2R59_001104"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEM8965511.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(9731..11440)
                     /locus_tag="U2R59_001105"
     CDS             complement(9731..11440)
                     /locus_tag="U2R59_001105"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEM8965512.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(11508..12776)
                     /gene="rseP"
                     /locus_tag="U2R59_001106"
     CDS             complement(11508..12776)
                     /gene="rseP"
                     /locus_tag="U2R59_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEM8965513.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(12937..13737)
                     /locus_tag="U2R59_001107"
     CDS             complement(12937..13737)
                     /locus_tag="U2R59_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEM8965514.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(13734..14546)
                     /locus_tag="U2R59_001108"
     CDS             complement(13734..14546)
                     /locus_tag="U2R59_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEM8965515.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(14741..15298)
                     /gene="frr"
                     /locus_tag="U2R59_001109"
     CDS             complement(14741..15298)
                     /gene="frr"
                     /locus_tag="U2R59_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEM8965516.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(15301..16023)
                     /locus_tag="U2R59_001110"
     CDS             complement(15301..16023)
                     /locus_tag="U2R59_001110"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEM8965517.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(16159..17040)
                     /locus_tag="U2R59_001111"
     CDS             complement(16159..17040)
                     /locus_tag="U2R59_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEM8965518.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(17139..17921)
                     /gene="rpsB"
                     /locus_tag="U2R59_001112"
     CDS             complement(17139..17921)
                     /gene="rpsB"
                     /locus_tag="U2R59_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEM8965519.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            18280..18759
                     /locus_tag="U2R59_001113"
     CDS             18280..18759
                     /locus_tag="U2R59_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HEM8965520.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            18976..20067
                     /gene="phnW"
                     /locus_tag="U2R59_001114"
     CDS             18976..20067
                     /gene="phnW"
                     /locus_tag="U2R59_001114"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HEM8965521.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            20060..20188
                     /locus_tag="U2R59_001115"
     CDS             20060..20188
                     /locus_tag="U2R59_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEM8965522.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            20192..20737
                     /locus_tag="U2R59_001116"
     CDS             20192..20737
                     /locus_tag="U2R59_001116"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HEM8965523.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(21191..22882)
                     /locus_tag="U2R59_001117"
     CDS             complement(21191..22882)
                     /locus_tag="U2R59_001117"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEM8965524.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(23302..24249)
                     /gene="arcC"
                     /locus_tag="U2R59_001118"
     CDS             complement(23302..24249)
                     /gene="arcC"
                     /locus_tag="U2R59_001118"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEM8965525.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(24364..25383)
                     /gene="argF"
                     /locus_tag="U2R59_001119"
     CDS             complement(24364..25383)
                     /gene="argF"
                     /locus_tag="U2R59_001119"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEM8965526.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(25474..26703)
                     /gene="arcA"
                     /locus_tag="U2R59_001120"
     CDS             complement(25474..26703)
                     /gene="arcA"
                     /locus_tag="U2R59_001120"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEM8965527.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            27164..27865
                     /locus_tag="U2R59_001121"
     CDS             27164..27865
                     /locus_tag="U2R59_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8965528.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(28474..29490)
                     /gene="tsaD"
                     /locus_tag="U2R59_001122"
     CDS             complement(28474..29490)
                     /gene="tsaD"
                     /locus_tag="U2R59_001122"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEM8965529.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(29487..29951)
                     /gene="rimI"
                     /locus_tag="U2R59_001123"
     CDS             complement(29487..29951)
                     /gene="rimI"
                     /locus_tag="U2R59_001123"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEM8965530.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(29958..30500)
                     /gene="rimI"
                     /locus_tag="U2R59_001124"
     CDS             complement(29958..30500)
                     /gene="rimI"
                     /locus_tag="U2R59_001124"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEM8965531.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(30484..31206)
                     /gene="tsaB"
                     /locus_tag="U2R59_001125"
     CDS             complement(30484..31206)
                     /gene="tsaB"
                     /locus_tag="U2R59_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEM8965532.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(31397..32377)
                     /locus_tag="U2R59_001126"
     CDS             complement(31397..32377)
                     /locus_tag="U2R59_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965533.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(32401..33885)
                     /gene="galT"
                     /locus_tag="U2R59_001127"
     CDS             complement(32401..33885)
                     /gene="galT"
                     /locus_tag="U2R59_001127"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEM8965534.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(33897..34886)
                     /gene="galE"
                     /locus_tag="U2R59_001128"
     CDS             complement(33897..34886)
                     /gene="galE"
                     /locus_tag="U2R59_001128"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEM8965535.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            35134..35301
                     /locus_tag="U2R59_001129"
     CDS             35134..35301
                     /locus_tag="U2R59_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEM8965536.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(35363..37174)
                     /locus_tag="U2R59_001130"
     CDS             complement(35363..37174)
                     /locus_tag="U2R59_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HEM8965537.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLKQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(37171..37536)
                     /locus_tag="U2R59_001131"
     CDS             complement(37171..37536)
                     /locus_tag="U2R59_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HEM8965538.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(37699..38094)
                     /locus_tag="U2R59_001132"
     CDS             complement(37699..38094)
                     /locus_tag="U2R59_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8965539.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(38112..39074)
                     /locus_tag="U2R59_001133"
     CDS             complement(38112..39074)
                     /locus_tag="U2R59_001133"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEM8965540.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(39074..39286)
                     /locus_tag="U2R59_001134"
     CDS             complement(39074..39286)
                     /locus_tag="U2R59_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEM8965541.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(39307..40005)
                     /locus_tag="U2R59_001135"
     CDS             complement(39307..40005)
                     /locus_tag="U2R59_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEM8965542.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(40025..40567)
                     /locus_tag="U2R59_001136"
     CDS             complement(40025..40567)
                     /locus_tag="U2R59_001136"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEM8965543.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(40699..41703)
                     /locus_tag="U2R59_001137"
     CDS             complement(40699..41703)
                     /locus_tag="U2R59_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEM8965544.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(41700..42689)
                     /locus_tag="U2R59_001138"
     CDS             complement(41700..42689)
                     /locus_tag="U2R59_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEM8965545.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(42686..43492)
                     /locus_tag="U2R59_001139"
     CDS             complement(42686..43492)
                     /locus_tag="U2R59_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965546.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            43658..44614
                     /locus_tag="U2R59_001140"
     CDS             43658..44614
                     /locus_tag="U2R59_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965547.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(44691..45209)
                     /locus_tag="U2R59_001141"
     CDS             complement(44691..45209)
                     /locus_tag="U2R59_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8965548.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(45297..45446)
                     /gene="rpmG"
                     /locus_tag="U2R59_001142"
     CDS             complement(45297..45446)
                     /gene="rpmG"
                     /locus_tag="U2R59_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8965549.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            45674..46120
                     /locus_tag="U2R59_001143"
     CDS             45674..46120
                     /locus_tag="U2R59_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEM8965550.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(46315..48210)
                     /gene="asnB"
                     /locus_tag="U2R59_001144"
     CDS             complement(46315..48210)
                     /gene="asnB"
                     /locus_tag="U2R59_001144"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HEM8965551.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        13668 a        10348 c         8501 g        15964 t
ORIGIN      
        1 atttcacagg atttgcggga gtttttgatt agtctttgtt caagtcgcga agcaattcat
       61 cgatatggtt gccatagaca actgattcat caagttcaaa gaacaattca ggtgtcttat
      121 aaatacttag attgtgccct aactctcgac gaatcaatcc tgatgcttta ttcaatccat
      181 cttgtgctgt tttcttatct gatgctaagt cagataaaat gctgtaatag atcgttgctt
      241 gctgtaagtc ccccgtaact ttcacatctg tgatcgttac gttctccaca cgagggtcac
      301 ggaccttttt gcgcaaaata tcattgactt cttttaagat ttcttgaccg actcggcggt
      361 cacggtagtt agccataatg attggcctcc ttttatcagt ttttagtcat ttttgacttc
      421 ttccatgata aatccttcaa ttacgtcatc tactttgatg tcattgaatt tttcaatcat
      481 tgcaccacat tcataaccca ttttgacttc tttcacgtca tctttgaatc gtttcagact
      541 tgcaagttgg ccttcataga ttacgattcc gtcacggatt acacggacac cgctatctct
      601 acgaatatat ccttctgtta cataggcacc tgcaatcgta ccaactttag aaactttgaa
      661 ggtttcacga acgatcattt gaccggtgat tttttcttca aattcagggt ctagcatccc
      721 tttcatcgca gtttcgattt cttcgatggc tttatagatg atacggtgaa gacgaatatc
      781 gacttcttca gtatcagctt gcacttttgc ctgcggtgta ggacgaacgt tgaaaccgat
      841 gataatagcg ttgctggctg ctgctaaggt tacatcactt tcattgattg ctccgacagc
      901 tgaatggacg atttttacac ggacaccttc cacatcaatc ttcttcaatg atgcagccag
      961 tgcttctgct gaaccttgta catctgcttt gatgattacg ttaacttctt tcaattcgcc
     1021 ttctttcagg ctttcaaata agttatccaa agtcacacgg cttgtggcag cacggttttc
     1081 taataatgca cgtttcgcgc gttcttcacc cgctgcacgt gctgtctttt cgtcttcgaa
     1141 gactacgaaa cggtcacctg cttgaggtac atcattcaag ccagtgattt ctactggcgt
     1201 tgcaggtcct gcttctttat cgcgacggcc aagatcgttt gtcattacac ggacacgtcc
     1261 gtaagtatta ccgacaacga ttgggtcacc aacatgaagt gttccttctt ggacaagtaa
     1321 ggttgacaca ggacctttac ctttatcaag acgtgcttcg atcactgttc cgattgcgcg
     1381 ttgtgttgga tctgctttta aatcttctac ttctgcgact aacaggatca tttccagcaa
     1441 ttcttcgatg ttttggccga atttcgctga gatctcaaca aagatcgttt ctccacccca
     1501 tgcttcagga attaactcat actcacttaa ttcttgcata acatgttgag ggtttgcacc
     1561 tggtttatca attttattta cagcgacgat gattggaacg cctgcagctt tggcatggtt
     1621 gattgcttca actgtttgtg gcatgacgcc atcatctgca gcaacaacta agatcgtgat
     1681 atctgtgata cttgctccac gtgcacgcat acttgtaaag gccgcatgtc ctggtgtatc
     1741 caagaaagtg attggtttac catcaatatc gatctggtag gcaccgatat gctgtgtgat
     1801 tccgccggct tcgccgcttg ttacacgtga atggcgtaat gtatccaata aagttgtttt
     1861 cccatggtct acgtgtccca taatcgttac gactggcgga cgtgagacta atttatctgg
     1921 atcgacttct tctgcctcga agaatttatc gatatcagca atgtcaactt ggactttttc
     1981 ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc gtatctttat ccagtgcttg
     2041 gttttgattg accatgacac caagcataaa taatttttta atgatttctg ctggctcacg
     2101 atgaattttt ttcgcaatat ctgctacgtt cataccttca gtatactcta atacatctgg
     2161 caattcacgg aatttgcgtg gtggtacagc tggtttagtt gattgttgct gtttgccttt
     2221 tttacctttt ttattataac gattacggtt attattatta aatttgccgc gattgttatt
     2281 gtttggtttg ttgttattgt tagtacggtt ttgattgccg ccttggctcg ttccttgacg
     2341 attttggctg ctggtatttc ccgtattatt ttggtttgtt gttggttttt ttccttgatt
     2401 cacttgaccg ctcccttgac cgcgatcttg ataactgcgg ttatttttat ttttttgttg
     2461 attgttcgtt gtttcttttt tacgttgatc gttcggctgt tgattggctg gttttctgct
     2521 tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg aacgcttgtt gcaatttctt
     2581 ctcatcattg ctagtaatcg cacccatatg gtttttcaca tcgatgccaa gttgttgtgc
     2641 tttttccacg acgtctttac tagatttttt gagttctttt gctaattcat agattctttt
     2701 gttgcccatg caatcacctt cctaaccttc aattagctcc ttggtcttct tcgcaaatcc
     2761 ggcatccatt attccgaata ccttgcgagg ttttccgatc atctgcgtga tttctgcttc
     2821 agaaaatagc tcaaagcaag gaacttcata atatgaactc ttatctttta tcttttttct
     2881 tgtattctcg cttgcatcgg ttgccacaaa caccaatttt gctttttgtt tgcggatttc
     2941 agcaatggtc agttcttcac ccgtgattag ttttcccgcg cgcatcgcta gaccgatgag
     3001 attcatggct ttttgccgat taactgtatt cattttccaa ataactcttt acgtgctttt
     3061 tggtgagtga catagtcaag aagttcttga taaaactcat ctgttaatgt tgtttcgagt
     3121 actcgatcga gaattttttt atcccaagct tgttgtactt cttccggctc aagtgagaca
     3181 tacgctcctc gtccaggcat ttttccagtt ggatcgatcg atacttcccc ttcttttgaa
     3241 cgggtgattc ggaccatctc ttttttaggt ttcatttcac ctgaaaccac ggatttgcgt
     3301 aaaggaattt tcctttgttt catctctttg cctccttact aaagttaagc ttctggtttt
     3361 tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt catcgtctgt taaatctgac
     3421 tgaacgattg cttcatcatg cagttcttct gtttcttttt gttgttcttg attttcataa
     3481 aattccgtca tgtcagattc tgatttgata tcgattttat ggttagtcaa tttagcagct
     3541 aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata attggtagtc tggaacgaca
     3601 actgtgcagg cctttggatt tgtctcatcg aagatcacat ccatgacttg tgcaggattc
     3661 aatgcatttg caatgaatac agctggatct tcattccatt cgacgatatc catgttttcg
     3721 ccttttaatt cattgacgat tgcttgaact cgttgtccct ttggcccgac acatgtaccg
     3781 actgcatcga tatttggatc atttgagcga actgccactt ttgaacgatc gccagcttca
     3841 cgggcgatgc tgacaatttc aacgattcca tcatagactt ctggtacttc ttgctcaaat
     3901 aagcggcgca ataggtctgg atggctgcgg ctaacaaata cttgcggacc tttagacgta
     3961 ttttctactc gggaaacata aactttgatt cgatcatgtg gttgataaaa ttcatttggc
     4021 atttgatctt gtttagaaag aactgcctca attttaccaa gattgacata aatataacgt
     4081 ttatcctggc gttcgacgat tccttgcatg atgtcttttt cataagcact gaattcgtta
     4141 taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa taacttgttt agccgtttgc
     4201 gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac ggatcgtatc accgatctca
     4261 tatgctggat tgattaaaag tgcatctttc aatgagactt ccaactgtga atccatcact
     4321 tcttccgtta cttcttttac cgcatagaca tggatctttc cttttttctg atcaaattcc
     4381 acttcgacgt tttgtgcttg gccatagtga cgtttgtatg cagaaaccaa tgctgcttct
     4441 aaagcatcga tcacgatttc ttttgagatc cctttttcag cttctaaagc gtctaacgca
     4501 tttaacattt ctttactcat tttttctgat tcctctccgt gattaaaatt ggatagctaa
     4561 gcgagctttt gcaatatttt ttcggtcaaa agtcaattct ttttctcgtg tttttatgcg
     4621 tattttcaat gtaagctgtt cagcatcaaa tgattgaaga aatccttcat attgtttttc
     4681 gccatctact ggttggtata aggagacatg gacataatca ccaagtgcct tttcatagtc
     4741 gctttctttt ttcaatggcc gctctgctcc cggggaggat acctccagga aataagcttg
     4801 aggaatcgga tctggatctg ctgcatcaag tttttcactc agtttctcac tgacaaaggc
     4861 gcattcttcg atatcgatac cgccttcttt gtcaataaat actcgtaaga accagctttt
     4921 tccttctttt acaaattcga cttcgacaag ttcaaaattt tgttcatcta aaatcggtgt
     4981 caccatttct gtgactgttt caacgacgct actcaaaagt ttcgcctcct taaaaaatta
     5041 agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc tcactcacag ttagtatcat
     5101 tacctataag aactatacca tactctgctt aaaattacaa gcagacagga aaacagatgc
     5161 ttatagcata tcgaataacg ataattgatt ttcatctggt agatctttca atacgccatt
     5221 gtcgttcata tattcgatca atgtttttga aactttaccg cgggtggcaa gatcttcttt
     5281 ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt tttgccacgt tggttcccaa
     5341 acttgggaca gctctaaatg gtgcgatcaa cgtatcacct tcaataacaa agttaacggc
     5401 atccgattta tacaaatcaa tcattccaaa tttgaatcct cgttccagca tttcattggc
     5461 taactccagc actgtcagtt gattcttttc ttttacggaa gcatctaatc ctttgtccgt
     5521 gatttctttc attgcttgtt tcacagcatc ttttcctttg cacatggaga ctagatcaaa
     5581 gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa atagggaaat aaaccttgaa
     5641 ataagcgaca cgaagagcca tcaatacgta agctgcagca tgggctttcg gaaacatata
     5701 tttgattttt gaacaagaat cgatatacca gtcgggcaca ttattttctt tcatcgccga
     5761 tagataggtt tctcgcaatt catcagggat cttgttccat tgtcctttac gaacagtttc
     5821 catgatttta aatgccatcc cgctatctaa tccagcatgg atcaaataaa ccataatatc
     5881 atcacgacag ccgattactt ccgccagtgt cgcatctcct cgtcgaatca attcttccgc
     5941 atttcctaac catacgtctg taccatgaga tagtccggaa atttgcagta gttctgcaaa
     6001 agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa cgagtgccga attctggaat
     6061 acctaatgtc cctgttttgg aataaatttg ttcctgactt actccaagta cttcaggacc
     6121 ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc gtttgtggat cgatccctga
     6181 taaatcttga agcatccgaa taacagttgg gtcatcatgc cctagaatat ctaatttcaa
     6241 tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt ttccattccg aattttgatc
     6301 gtctgctgga tattggatcg gcgtaaaatc atagacatcc atataatcgg gaataacgat
     6361 gatcccccct ggatgctggc cggttgtccg tttgactcca gtagcgcctt ttgctaatct
     6421 gtcgacttct gcacttcgaa actgcagatt attgtccctt tcgtatcctt ttacatagcc
     6481 atatgctgtt ttgtcggcga ctgtaccaat cgttccggca cggtaaacat agtcttcgcc
     6541 aaacaatact ttcgtatagt tatgggcttc tgcttgataa tcacctgaga agttcaaatc
     6601 aatatcgggc actttgtctc catggaatcc taaaaatgtc tcaaatggaa tatcatgacc
     6661 gtctttgttt aagcgtgcac cacattttgg acattgtttt tctggcatgt caaatccaga
     6721 accatacgta ccatcttcaa aaaactcgga atattggcac tctggacaat aataatgagg
     6781 ggctaacgga ttaacttcag tgattcctgt catcgtcgca acaaagctag agccaacaga
     6841 gccacgtgaa cctactagat agccatcttc attactttta tgcactagtt tttgggcgat
     6901 cagataaata accgagaagc cattaccatt aatagaattc aactcttttt ttaatcgttt
     6961 ttgaatgatc tcaggtaacg gatctccgta catttgtttt gcttttgtgt aactcaattc
     7021 tgatatttca tcttctgaac ctggaatctt cggtgtataa agttcatctt tgactggaat
     7081 cacttcttcg cagatatctg cgattttatt cgtattttct actacgatct ctttcgctgt
     7141 ttcttcccct aaaaagtgaa atgcagttag catctcatcg gttgttcgga aatggacatc
     7201 cggcaaacta tgacgattca acggattcgc tccgcccata gaattgatca aaatttttcg
     7261 gtaaatggca tcttcttcgt tcagataatg tacattacct gttgcaacaa cgattttatc
     7321 caaacttttt ccgatttcta ccaaattttg gataatttct tccaaatcat gttcattttt
     7381 taccaattct tgctcgatca aaggcgcata gaccgctttt ggcataactt caatataatc
     7441 gtagaatttt gctcggtttc ttgcctcttc tacccctttt tgcatcatgg cttcgaatat
     7501 ttctccctta tcacaagctg agccgatcaa tagattttca cgcatctttt tcaattggga
     7561 gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc gacattgaaa tcagtttgaa
     7621 caaatctttc agtcctgcct gattttttgc taaaatcgtt acatggaaag gtcgagccct
     7681 tttgtaagaa tctccttctc cgatatgctc atttagctga tcatgataaa gcatgttatg
     7741 attgtccatt gcctctttca caaagatcca tgctaagtga ccagttgctt cagcatcata
     7801 gattgctcgg tgatgctgtt ccaagctgac accaaatttt ttagataaca cacctaatcc
     7861 gaaacgtttg aattgaggat acagatatct agctaattcc aacgtatcaa tgactggatt
     7921 ggccgcttca ggaataccat accttgcgta gctagtattc aagaacccca tatcaaaagc
     7981 cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca aggaacatcc gcaatacttc
     8041 ttcttccgac tttgatcctc gaaccattcc atccgtgata ccagtcagat ctaccgttgt
     8101 tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag ctttcgatca catttccttt
     8161 atacattttg actgcggcta gctcgatgat cgtgtcatat actgcagaca atcctgtcgt
     8221 ttccacgtca aatacgacat atgtggcttc actcaatgct tcatgtgcat cattataagc
     8281 aattgggaca ccatcatcta cgacattcgc ttccacgccg tataagattt tcacacctgc
     8341 tttttttcca gcactatgtg cttccggaaa ggcttgcgca ccaccgtggt ctgtaatggc
     8401 gatagctcgg tgtccccatt tccctgcttg tgccacaaga tcagagatgc tgtttgttgc
     8461 atccatcgta ctcatattgc tatgaacatg aagctctact cgtttttccc cttcaggagc
     8521 ataatctttg cgaggtgtat gtttgacttc tatgatatct tgcgcattca tgaccaaatc
     8581 acggacaaac gtatcttctt gaatacttcc tcgtaccttt aaccagctac cgacactgat
     8641 cgcatcaaat acttgttcat ctttttcgcc gttcgagaat tttttgacga taaatgatga
     8701 agtataatct gtgattttca aagtcaagat cttgcgtttt gaacgtagtt ctctgacttc
     8761 tttgtcgaat acgtacccct caagtgtgac tcttcgttct tcttcaacga tactgatcat
     8821 tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc tggatgtgga tgggtccttc
     8881 aagagctggc gattgctctt ttctttcctt tttcttttgt tcgtggacaa ctagactttc
     8941 agctgcttgc ttcataaagg cttctgcctg ttcttgtttg cgttcttcaa aaagtttcaa
     9001 tactcgttcc gcttgctgct catccacttc tggttcgata cgaaattttg ggaatccgta
     9061 actgacgaac aactcttcta ctaatggcaa gtattgttgc ttcaaataag aaatagctcc
     9121 tgtactgtcg attggcaaga tgactttacg atcttttatc acaggtacct gcgttttcaa
     9181 tacttgctgt gctagtggtg tatcgcattg ctgattttcc aaagcttggg cccagtaatc
     9241 ttgcaagagc tgttcatcga atgtctggtc atctgctaag atattcagtt tgacttgtgc
     9301 aatatcttta aaagcgatag tcagatgctg agtcaatgac cgatatagca taataggcaa
     9361 aattttggaa aaatgcagcg taaattccca taaacgcgat ttacgatgga ccactacact
     9421 atccatttca ccagcagtaa gcagtggatg atttttttct gcttcctcta gttggatttg
     9481 ttccaacagt ttttcaaata aatctcgttt ttctgacaaa gatatacgcc ctttctgatg
     9541 agaaacaatg caattgatcg catcttatcc tcttcttttt cagtaccttt tagtatactc
     9601 gttttttctg agttttacat taaaaaattg gaactgcgat tcaaatcgca gttccaattt
     9661 taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag ctatttttat tttctgtgtt
     9721 ttaacgctta ttattcgcct tggttcaaga ggattggtaa agtattcacc aattcttctt
     9781 tacgtacttc aaccatttcg ccagttttct tgattttcac ttctacgatt ccatccactg
     9841 cttttttacc gacagtgatt ctgattggac agccaatcaa atcagaatcc gcgaatttca
     9901 ctcctgcgcg ttcatttctg tcatcaacca gtacttcata gccagctttt gtcatcgctt
     9961 cttctagttc attcgtcagg tttgtttggt attcgtcttt tagattcatt tggacgatat
    10021 gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc ttgttcatct gaatgttgtt
    10081 ctacgattgc tgataataaa cgacttacac cgataccata acagcccata atcacaaatt
    10141 tttctcgtcc attttcgtct agtacagttg ctcccataga ttcactgtaa cgagtgccga
    10201 ttttgaagat atgtccgatt tcgattcctc gagtaaaggc aagaacacca ttgttgtctg
    10261 gtgaaggatc tccttcttgt acaaaacgaa gatcttcata agaaagtaca gtgaaatcgc
    10321 gttctggatt cacattttta tagtggaatc ctgtttcgtt cgctccagta atggcattcg
    10381 ctaaatcttg gacataacgg tctgcatata cttttacgtc atctgaaaca ccgactggtc
    10441 cgacagaacc aaactcagca cctagatatt tttgtgcttc ttcttctgtt gcttcttcta
    10501 aaaagtcagc agataaaaag tttttcagtt ttacgtcatt gacttcatgg tctccgcgta
    10561 ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac agacttgatg attttttgag
    10621 gttcaacaga aaagaaatct gctacttcgt caattgattt tacgttaggt gtagctactt
    10681 tctccaattc aagctgtgtt tcatgcgatt tttttgatac atagtagctt gtagccatct
    10741 ccaagtttgc agcataatca ctttcagtcg aataacagat cgtatcctcc ccgatttctg
    10801 agatcgccat gaattctttt gagtctttcc cgcccattgc gccaccgtct ccgataatcg
    10861 agcgaaattc taagccacaa cgcttgaata cttcggtgta ggctttttcg taatctttat
    10921 atgtctcgtc caaactttct tccgttgcat ggaaagaata cgcatctttc atgataaact
    10981 ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc acgatattta ggttggattt
    11041 gataaagatt taaaggtaat ttcttatatg aattgatttc attacgcatc aaatcagtaa
    11101 aagtttcttc gtgagttggt ccaaggatca tttttcgatc attgcggtct ttgaaacgat
    11161 acaagtttgg tccatatgtt tcgtaacgcc cggattcttc ccaaagttct gctggcaaga
    11221 tggcaggcat cagcatttct accgctccga ttttttcaaa ttcttcccgc ataatgcgtt
    11281 tcagtttttc caatacacga tttgctaatg gcagatatga ataaataccc gctgatactt
    11341 ggcggatata tccagctctt agcaagattt gatggcttaa tacttctgca tcatttggaa
    11401 cttcgcgtaa tgttggaatc aacatttttg attgtctcat tctatatact cctttatttc
    11461 ctcaaaatag ttatcgtttg ttattatacc ctatttgtca actttttcta gaaaaagaat
    11521 cgttgaatat cgttccatgt aactagcacc atcaacaaca ttaaaaatcc aaagccagct
    11581 aatgtcaata ttccttcttt ttcttgactt aatggtttcc cgcgaatccc ttcaaaaata
    11641 ttcaagacta atttcccgcc atctaaggca ggaatcggaa gcagattgac gattccgaga
    11701 ttcattgaaa gaagcgccat caaactaata acagttgtta caccttgatt tgctgcttct
    11761 gaagacaatt ggtacatcat gacaggtccg cctaatttat ctaaactgaa acctgtaaat
    11821 agtgatccta aggctttgaa aatttccaat gaaccgctga aagcttgacg cgtccctcca
    11881 atgatcttat ccataaaacc tgtattcatt ggggctttta taccaagttg gccaactttt
    11941 tcgccatttg actctacaga tttcggtgtc acgtcgacag attgcacctg accttctcgt
    12001 tcgatcttaa agtctaatgt tttatccgga tttttcgtaa tgactgttgt cagatcattc
    12061 catgaatgga tttcttttcc gtccacactg actacctcat cattttcttt taagcctgct
    12121 tctgccgcag ctccattagg catgatctct cctacgcgat tagtgttcgt cacttgaaca
    12181 ccaccttgca taaatgccag aatgatgaat aacaggattg ccaaaataaa gttattcatg
    12241 ggtccagcaa agttggtcag catacgctgc cacaatttag ccgattggaa ctgtacgtct
    12301 tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa tcgtcgcatc gtgatcaaca
    12361 gggtaggtta ctacttctgt ttcgtctcca ttcacataac cagtgatagt cagctcatct
    12421 tctaaatcat aacggctcaa ttccatcggg atagcatttg tcaattggat tttcttactt
    12481 aaatttatct tctctacgat gccgtcagaa tttagtaaaa gagaaagagg cattcctggt
    12541 gccatttctg tttcatcatc cccattgcct gccattcgaa cataaccgcc aataggtaat
    12601 aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc cataaatttt cggacccata
    12661 ccgatagcaa attcgcgaac gaggattcct gatcgtttcg caaagaagaa atgaccaaac
    12721 tcatgaacaa tcactaatat accaaaaacg atgataaatg tcagaatcgt tttcatagct
    12781 tttttctcct ttacttgttt tttgtgtttt ttataaaaca acgataaaac actataattt
    12841 taccatagta taccaaagac accaatagta tcaatataat gaaaaataaa aacctgcgtc
    12901 ttttatgaaa ttcacaaaga aacgcaggta tacttactaa ataatgccaa ataaatgcat
    12961 gataggaaat acaaacagca aactgtcgaa acggtctaag attccaccat ggcctggtaa
    13021 gatatttccc gagtctttca catcataatg acgtttgatt gcagattcga ccaaatcacc
    13081 aaattgtccg actgctgaaa aaataatcgt catcagaagc atgacaaaca taccatgatt
    13141 aaatagttct tttgctgggt atagcaataa ataaagaaat gcgactacaa cagcactacc
    13201 aataccaccg agcgcacctt caatcgtttt gttgggcgaa atatcaggac ttaacttatg
    13261 ctgaccataa cgtcgaccaa ccatatatgc tccgatatca gttgcccaaa caataaatag
    13321 accaaatatc aaaacagcca agctttctgt tcgtgcattg acaaaattct ggaaacctat
    13381 tcccacatac aagctgacaa gcacaggaaa acctgcttca tcaatcgtat acgtattttt
    13441 agaaataact gatgttccta aaagaatcat aactataaga taaaataaca taaatgtact
    13501 tacattctct ggaagaaaga aaaaccatct ttcttttggc aaaacaagta acactgcacc
    13561 aacggcggat aaaactcctt caaaacttaa gagtgtcaat cctttcatcc gaaacagctc
    13621 gtaaactcct attactgcta agattgctgc tgtaagctca accgctatgc ctccgatcca
    13681 tataatcgga ataaacaaga ctagcgccac ggctgctgtg accacacgtt gtttcatgac
    13741 tgatcccctt tctcatcttc tgtttttttt acaccgccga atcgacggtc tcgattttga
    13801 taagaggcga ttgcttcttc aagatgcgca ccatcaaaat caggccaaag cgcttttgta
    13861 aaatacagct cactatatgc gatctgccat aacagaaaat tactaattcg ctcttctcca
    13921 cttgtacgga tcatcagctc aggatcttgt aactctttag gcaagaaacc tgtcattaaa
    13981 tgcttagcaa tcaattcatc atcgatttct tctgcgtgta tttctccttt tgctacttct
    14041 tcggcaattt cttggacagc agtcacgatc tctgctctgc ttccataatt caaagcaaaa
    14101 ttcaatacca ttccagtatt gttttttgtt tgctcaattg cacgtcttac agcatcttgc
    14161 gtatgttctg gcaatacgtt ttcataaccc atgacatgaa ctttgacatt ttctttaatc
    14221 aattctggta cgaacgtatc aaagaagtcg acaggtagtt gcatgagaaa acttacttca
    14281 tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa gcgtcaacac tttcactcca
    14341 agccttgatg ctttttttgt gactttcttt actgtttcca tgccttcttt atggccagca
    14401 actcgtggca aacgacggtt ttgcgcccaa cgaccattgc cgtccatgat gatggcaatg
    14461 tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc ttttttcttg aatatatttg
    14521 tttttttgcg gaaaaaaacg taacattctt tttcctccta tacttaaaag attcccacta
    14581 tcttaagtat tatagcaata tctaactgtt tttcctatga aatcattgtt tttttattta
    14641 aaaactgaat aattttttct ttttttaatt tttaaataaa agaaatataa ataaaaacag
    14701 aggaagcgga atgatccgcc cctctgtttt tatgatttta ttaaacttcc aataattctt
    14761 tttctttatc agcagcgatc ttatctactt ctttgatgct gttatctgtc aatgtttgta
    14821 cgtctttttc taatccgcgc aaatcatctt cggtaatatc accatttttt tgttgttttt
    14881 tatattcatc gatcgcatca cgacggatgt tacgaatcgc gatttttgca ttttctgctt
    14941 cttttttaac atctttagct aattcttttc tgcgttcttc tgtcagttgc gggataacta
    15001 agcgaatgac atttccatca ttggttggac tgattccgat atcacttgcc ataatagctt
    15061 tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat cattaaaaca cgtgcttctg
    15121 gaatttggat tgatgccatt tggttcaatg gtgttggcgc accgtagtag ttcacagtaa
    15181 tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat ttgcccaagt tcacgttgaa
    15241 gattttgtgc tgcttttttc attttttctt ttgcttctgt cataattgca tctgccattt
    15301 ttatttcccc cttacagttg ttccgatatt ttcgcctaag attgcacggc gaatatttcc
    15361 gtgttcattt aaattgaaga caagcagtgg aatatcatta tccatgctta gtgaacttgc
    15421 agttgaatcc atgacttgta atcctttggc aataacttcc agatgagtca gttcttcaaa
    15481 ttttactgca tttgcatcta ctttcggatc agcagaataa acaccgtcta cattgttttt
    15541 agccatcagg ataacatctg cgccgatttc tgccgcgcgt aatgctgctg ttgtgtctgt
    15601 cgagaagtac gggttgccgg taccgcctgc aaagataacg atccgtcctt tttctaaatg
    15661 acgttctgct ttacggcgaa tatatggctc tgcgatttga cgcatttcaa tcgaagtttg
    15721 cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt aaagctaagg cattcataac
    15781 tgtagctaac atacccatgt aatcagcttg agcacgttcc atgcccattt gtgctccgat
    15841 ttgtccgcgc cagatatttc cgccgcccac aacgattgcc atttcaacgc ccagctcgtg
    15901 aacttctttg atttcttgga tgatttcttt gattactggt ggtttgattc caaatcctgc
    15961 gtccccagct aaagcttctc cactcaattt taagactaca cgctgatatt tcggtgtgac
    16021 catgttcatt cctccaatat tttctattgc cattttacca tacttagatg atttcgacac
    16081 tctaagactg gtttttcttg ttttgcttaa aaaaagggag cgcacaaacc gtgcgttccc
    16141 gtctgttatt caacagaatt attttttcac ttggctcata acttcttcta caaagttatc
    16201 ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg aatgttttaa cagttgcgcc
    16261 ttttgatgca acgtattttt caacagtcat atcaggatct ttaacgaatg gttggtccac
    16321 caaagcgatt tctgctttga atttcttcaa gcgtccttct accatttttt caacgatatt
    16381 cgctggtttg ccttcgttca atgcttgttc tgtaagaaca gttttttcat gttctaattc
    16441 agcttctgga atttgtgatt cgtttacata acgaggattg atagctgcta cgtgcatagc
    16501 tacgtctctt gcaactgttt cgtcagttgt tccatctaga acagtcaata cggcaatacg
    16561 tccgcccata tgcaagtatc caccaaatgc agcattgtcg tctttttcta caacttcaaa
    16621 gcgacggaag ctgatttttt ctccgataac ttgagttgct tcgatcaagt cagattcaat
    16681 tgtaccttta tctgttttga ttttcattgc agcttccatg tctgctggtt tgttttcagc
    16741 aacaagttct gcaatttctt ttactaaatc ttggaacatt tcgtttttag aaacaaagtc
    16801 tgtttctgag tttacttcaa cgattgctgc agtgttacct ttcacagcaa ctgaagccaa
    16861 tccttcagct gcaatgcggt catttttctt cgcagccttt gccattcctt tttcacgtaa
    16921 aagatcaact gctttttcca tgtcgccttc tacttcaact aatgcttttt tcgcatccat
    16981 cattcctacg ccagtcattt cgcgtagttc ttttaccatt ttagctgtaa cgtctgccat
    17041 gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct gcttcaaagg agagtgaggc
    17101 ttgtcgccca gcctttgaaa cagctccatc attcaaaatt attctgctga agaattgtcg
    17161 ccttcaacaa catctacgat ttcttcgatt gatgttgctg tgttttcttc tgtgaaatct
    17221 tcttcaacta cttgatcttc accttggttt ccttcgatga aagcatcagc catttttgaa
    17281 gtaatcaatt taacggcacg aattgcatcg tcgtttgaag ggattactac gtcgatttca
    17341 tctggatcgc agtttgtatc aaccatagct acgattggga tatttaattt gtgtgcttct
    17401 tgaacagcaa tacgttcttt acgtgggtca acgatgtaca ttacatctgg gattcttggc
    17461 atatcagcga taccgcctaa gaatttttca agacgttcac gttctttgtt caaaccagca
    17521 acttcttttt taggtagaac ttcaaaagtt ccatcttctt ccattgcatt gatttgtttc
    17581 aaacggctga tacgtttttg gatagtatcc cagtttgtca atgttccgcc taaccaacga
    17641 tggttaacga agtattgtcc tgcacgagtt gcttcttctt tgattgcttc ttgtgcttgt
    17701 ttttttgtac ctacgaataa tgctacgccg ccttcttcag caacgctctt catgtaatca
    17761 taagctgcat ctactaattt aactgttttt tgcaagtcaa tgatgtagat tccgtttctt
    17821 tctgtgaaga tatatttctt catttttgga ttccagcgac gagtttggtg accaaagtgt
    17881 acgccggctt ctagtaattg tttcatagaa attactgcca tgtttgtttc ctccgatttg
    17941 gttttatttt tcctcttctt atcttctacc ttgccggcaa actttttcaa gcacctaccg
    18001 acaatccaat aagaatgtgg atttgctgat gcataaagca ccctcagcta ttatacagac
    18061 aaaagatccg tatcgcaaga gcaaatatac ttttctgctc aacattcaat agtttacctg
    18121 aaagataaaa agaattcaag aaaaacagta gatttctctt tgtttcttta ttatcctttt
    18181 tccataaaat aattttaggt ataaaagacg aatattattg ggcaatcctt cttttttttg
    18241 ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa tgcgcaaagc tcaaagacat
    18301 ttgctgatta aacaagtcat tgaagaattc ccgatccgta cgcaagaaga actattaaac
    18361 aaacttgggc attatggcgt taccgccacg caggcaacga tttctcgaga tatccgtgat
    18421 ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc gcttcgtatt gtttcgcgaa
    18481 aaaggaactc ctgagactag gactgaggaa gaggatcggc tggttcaaat gattgaagac
    18541 attgtattga aagtcgaacg agtccacttt ttgacgatcg tcaatacctt gccagacaat
    18601 gctcatttat ttgcatctgt tttagatgag atcaaacctc cctctattgt cagtacaatt
    18661 gctggattcg atacgatcat ggtcatctcg gaaaatgagg aggacgcaaa acgagtagaa
    18721 gaatttcttc accatccaac tgaagtatca cttttttaat cagagcacgt attcctaata
    18781 tggaatgcgt gtttttttat tttcaatatt ttccttattg aataaacctt tacactcttt
    18841 acaaaaatac atcatttttt attcaaattt ttcaacacct tgattgaatc acaataatca
    18901 tcatttatat tggatgttaa caagagcagc ttcttgctct ttgtgtattt caaaaaagaa
    18961 atgaaaggaa atcatatgta taaattatta acttctggac cattgacgac ttctgaaaca
    19021 gtgaaaaatg ctatgctgat cgatcattgt acttgggatc aagaatacaa agaaattaca
    19081 caatggataa gaaaaaaatt attggatctt gctcaagtat cggaaggaat atacacaacg
    19141 gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg tattaagttc tgtgatcagg
    19201 ccagaagata ctgtactgat ttgttcaaac ggcgcatata gacaacgaat gatcaacatg
    19261 tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat cggaacatca aatcctccaa
    19321 gctcatgtga ttacacagct gattgaagag aatccgtcta tctccgcact agcaatggtc
    19381 catagcgaga ctacttccgg tattttgaat aatttggaag agattgctgc tgtcacacaa
    19441 gaaagagatc ttttgtttat agtggacgcg atgtcaagct ttggtgggat accgatttgt
    19501 gtagccgaac tagggattga ttttttgatt tccagctcaa acaaatgtat tcaaggtgtt
    19561 ccaggctttt cttttgtact tgctaataaa gcggaactgg aaaaacgaaa aaatgttagc
    19621 cgaagtttgt cacttgatct atatgaccag taccgcgtga tggaaaacga gaatggcaaa
    19681 tggcgtttca cttcccctac ccatacggtt ttggcttttc aacaagcgct gaaggaacta
    19741 gaggcagaag gaggaatcga aactcgatat tcacgttatc tcgccaataa tcatgtgcta
    19801 cgacaaaaaa tgacagagat ggggttccag cctttcattc aagaatatca ggggccattc
    19861 atcacctctt ttctttaccc taaggactgg cgatttgatt ttaatcattt ttatcagtat
    19921 ttaaagcaaa atggatttgt gatctatccc gggaaaatca gcgatcatga atgttttcgt
    19981 atcggaaata ttggcgagat ctatccggaa gatattttgg aactgacagc aattatcaaa
    20041 gactataagg agaacgttaa tgattaaaac tgtaattttt gattgggcag gaacaactgt
    20101 ggactttggc tgtatggctc ctgtccacgc ttttagaaat gcttttctag aaaaaggaat
    20161 ccaactgact gacaaagaaa tccgctaacc gatgggaaaa ttaaaatggg atcatatcca
    20221 acagcttctt tccctccctt ctgtcaaaaa acaatggata gctatttatg gacaactacc
    20281 tcaggaaaaa gaggtggagg aattgtatca acaatttgaa cattatctgt ttaaagattt
    20341 ggtcaagcat tctaccttga aacccgacac attggaaacg atcgaacggt tgagaaacgc
    20401 tgggatcaat attggttcca cgaatggatt taatgctcct atgatgacaa tcgtagcaga
    20461 aaccgcaaaa aaagaaaggt attcaccaga cttcatggca acttttgaag acgtcgaagg
    20521 gtatggtcga ccgtttcctt atatgatcca taaaaacatg cagtacttca aaaacaagtc
    20581 ggttgatgaa gtaatcaaag tcggagatac ggtctcagat atccaggaag ggaaaaatgc
    20641 cggagtgttg acagtaggtg taattgaagg tagttcgcta atggggattt cttatgatga
    20701 gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac agtctgttgc tcttagattc
    20761 caacaagccg gcgctgatat ttgtgtaaac aatttaaaag agttaacaga atacattttg
    20821 tacgctgaca tgaatccaga atgactttta tacaaaataa gaggttgtga aaaagctgtc
    20881 ctgtatcaag taataaaaac agccaagcaa aaatagctcc tcatattttt cgtttggtta
    20941 ggcttattac cgcagatgca agcttttgaa caccgtttat tcgaaaaaaa aaagggagct
    21001 gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa acagtgttta agagacaacc
    21061 tctccactaa acggtgttca ttcagctgac tctcggtatt tgctcaaaaa acgataaaat
    21121 ttgaaaagct attttctctt ttgtttctct aatactcgga tcagaacgct gatttcacat
    21181 tctctttttc ttacatctta tctggtgcat gaagtcctag caaacgaagg tcttctttca
    21241 ataatacagt cactgcataa actagagcta agcgtgcttc tttttgttca tcatcagcta
    21301 aaatcttcgt atgagcatag tatttgttga atgcttgtgc taatttgatt gcatgtttcg
    21361 caatcactga cggttcgtat ttttccccag cagacaagac cgtttcaggg tatttttgaa
    21421 ctaatttaac cacttcccag ctggtatcgt cattcaatgc atagtctgct gtttctgaag
    21481 ggacaaatcc tgctttttcc aacaggctga ctgcacgagc atgtgtatat tgcacataag
    21541 gtccagtttc tccttcaaat cgaacaactt cttccaggtt aaagtcaaat gtattcagtc
    21601 gatcgttttt caaatcgtgg aaaatgactg ccccaacccc aacttgttta gctacagcat
    21661 ctttgttttc caaatcaggg tttttctcgc tgatttgttc tttagcagat tggattgctt
    21721 catttaatac ttcttctaat aagacgatct ttcctttacg agttgataat tttttaccac
    21781 cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc agaccagtca aagcccattt
    21841 ccttcaagac agctttcaac tgtttaaaat gatagctttg ttcattccct actacatata
    21901 gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc agcagctaag tcacgtgtaa
    21961 tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg attcaggtca taagcagata
    22021 ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg tttttcttct aaaagtttga
    22081 cgatttcatc catcttgtca ttgtagaaag cttcaccgtt caacgaatcg aaacgtactt
    22141 ccagcagatc atagatttta ttgaattctt tcatcgattc atcacggaac cattgccata
    22201 attgaatagc ctctttatcg ccttcttcca gacgtttgaa ccaagcacga gcttcttcat
    22261 ttaattctgg ttctgtttca gctacttcat ggaattggac gtataaacga agcaattcat
    22321 tgattggttc tgctttaaca gcttcttctg taccccattt tttgtaagcg acgatcagtt
    22381 ttccaaactg tgttccccag tcacctaaat ggttgatgcg gattggctga taaccgattt
    22441 tttccataat gaaaccgatc gaattaccga taactgtcga acgcaaatgt cccattgaga
    22501 ttggtttggc aatattagga gaagacatgt cgattggtac tgttccttga ttcccgatgt
    22561 tgctatcccc ataatgttct ttttctttca ctactgtttg caaaactttt ttgctgataa
    22621 gttctttatt catgaaaaag ttcaagtaag gtccgacaac ttcgattttt tcaaagttgg
    22681 cagaatcgat tttttctgct aaatctgcag cgatttgctg tggcgctttt cggtaaactt
    22741 ttgctaatga aaaggctgga aatgcaacat ctccgtgttc agctgatttt ggattttcta
    22801 gtaattgctc gacttgttcc agtgttaaat catctttgac agcgtcatag acagcttttg
    22861 cgacaagatc tttattattc atctttattc ctcctaaagt gttcccttga ttgttaaaca
    22921 aaaaaaatct ctagcgacgg catacttagt atgccatcac tagagacgag atttcccgcg
    22981 gtaccactcc aattgtccta aaaaaggacc agctccatct gatatcggta gacgaccgtc
    23041 tgtttaaaac agaattctcc aagtgcgctt cgttgtatct tcttcattcg gcttccacca
    23101 cttccgaatt cgctagccaa gaatgataca agtactctct tgttcaacaa atcttagtct
    23161 tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa ggctagtcgt ttcataaaaa
    23221 aacaatccag atggcctaaa ggagaagaaa taccacctgg atagctataa atcatttcgt
    23281 aaatacgaaa gacttaacaa attaatcagc tacgataatc gttccttctt cagaagctaa
    23341 aagattctcg atattttcta aagaagtgat gattgcctta gcgtttggtt ttgcttcaac
    23401 aaatgcaata gctgcttcta ctttcggaag catgcttcct ggagcgaatt gcttttcatc
    23461 aatgtattgt ttcatttctg aaacagtaac agtttctaat ttcttttgat ctggtttttg
    23521 gtaattgaca tacacattgt ctactcctgt caatacgatc agcaaatccg catcgatgat
    23581 ttcggctaat ttttctgaag caaaatcttt atcgattacg gcttctcgtc cttctaatcc
    23641 agtagctgtt tctacaacag gaatcccacc gccaccaaca gagactgtga taactccttg
    23701 atcgaccagc gtttcgatga cacgtgcttc tttaatcgag atgggtttag gggaagcgac
    23761 tacttttctc catccacgtc cagcatcttc tttgaatgtc acagtggagt cagcattcat
    23821 ttgttctttg gcttcttctt ccgtgtagaa tggaccgact ggtttacttg gatttttgaa
    23881 tgaaggatca ttttcatcca caataacttg agtgactaaa gaaaccacat ctttatcgat
    23941 ccctttttcc ttcagtactt cgcccatggc gttttgtaac cagtaaccga tagatccttc
    24001 tgtcattgca acacatgtat ctaaaggcat tgccggtgtt ttctcagaat cagcagcttg
    24061 ctgctgaatc aataggttac cgacttgcgg accatttccg tgggagatga tcaattcatc
    24121 tccttgttcg ataaatttca ctaaatactt tgctgtttcc attaacgctt cttgttgggc
    24181 ttttgcactt gcatccgtag acaagatggc attgccccct aaagcgacaa ctacttttcg
    24241 tttggccatt tcattcgtcc tttcttcagt tctaccgaat tttctagata acaaaacgag
    24301 ccagcgtttt gtgattttcc ctcaatgctg actcgttttt tcgtgagatg aatgtggtta
    24361 tgcttaaacg cgagggataa acaagttacc taatgttgct gccatgatcg ctttgattga
    24421 gtgcatacga ttttctgctt ggtcaaattg acgagcatat ttgctgcgga agacttcatc
    24481 tgttacttcc atttcagtga tgccaaagcg ttctttcatt tgttcaccgt aaacagtgtt
    24541 tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa cgatctgtgt tgtgtgtttt
    24601 ttctaccatt tccatattga tttggtaagg tttcaacaat ttgatacgtt cttcgaattt
    24661 atcttcttca cccattgata cccatacatc agaataaagg acgtctgctc cgtctacacc
    24721 tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat ttttcagcaa agccttctgc
    24781 cattttgacg atttcttctt caggttgtaa ttcttttggt gcaacgatac gcatattcgc
    24841 tcctaaaatt gcacctgtga ctaataaaga gttagccata ttgtttcgac catctccgca
    24901 gtaagcaaca gtgatacctt ctactgttcc aaagttttct tggatagtta aaaagtcagc
    24961 gatcatttgt gttggatgcc attcatcagt caagccattc caaactggaa caccagagaa
    25021 ttctgctagt tcctctacca ttttttgact gaatccacgg aattcgattc cgtcaaacat
    25081 acgtcctagt actttagctg tatcttctgt ggattctttt ttacctaatt ggatatcatt
    25141 tgcacctaga tattcaggat gtgcacctag atcgatcgct gcagtagtaa atgcagaacg
    25201 agtacgtgta gatgtttttt caaataaaag cgcaatattt tttccttcta gatagtgatg
    25261 tgggatacca cgttttttca agtctttcaa gtgttctgaa aaatcgatca aatattgtaa
    25321 ttcttctttt gtaaagtctt tttctgctaa taagcttctt ccttggaata ctgattcttt
    25381 catattaaac attctccttt agattgtttt tatttaagat taaagaggaa atcccgacgg
    25441 cagctgacag taagactgcc gtcaggaaac aaattacttc aagtcttcac ggacaagtgg
    25501 ttggctcatg cagcgtggac caccacgacc tcgtgacaat tcacttgaat tgatttctaa
    25561 cactttgatg ccatagctac gaagcaattc gttcgataca taatttcggt tataagtgac
    25621 tacaacacct ggagcgattg ccaatgtgtt tgatccatca ttccattgtt ctcgaggtgc
    25681 aacgatctca tctccattac cagttgggat cagtacaaga tcatctaatc caagagcagc
    25741 tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg atatcatcac catctggttc
    25801 gattgtaaag acatccatct taccgtcttt actttgaatt gctggatgga tagtgaattt
    25861 atcgtgatct accattgtaa atacggtatc caaatgcatc attgcacggt tgttcggaat
    25921 tttgattgcc aacacttttt caaatcctga attttttgcg aataggtggc gtgctaattt
    25981 ttctaaagct ttcgcattag ttcgttgaga aatcccaaca gctactactt tatcgcttaa
    26041 gatcaattcg tctccgcctt cgatatgatc tggattttca cgatccaacc atacttcgat
    26101 tcctttattt gcaaatcttg gatgatgttt caaaatatat tctgtaaaca tcgattcacg
    26161 acgacgtgct tcaaaagtca tcttattgac tgtcatccca tttcccattg atgcggaagg
    26221 gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa aatggatagt catcgtctgc
    26281 tgacagatca tatagactgc tagaacgtac ttcgatatct tttgtacgaa ccccagccat
    26341 gattttatct accatttctt gcgtttccat tgatagaagg aactcatgaa gaccctctct
    26401 tacagcattc gatgcaatat gagattcatc caacatttta ttcaagaatt gttctttgac
    26461 attgcctgcg tcaatcgctt ctgccgctaa tttttccaag taaagagtct cgacgccttc
    26521 attttgcaat gtcttcgcaa agttgtcatg ttcttcttga gcaatcggaa gatatggaat
    26581 atcatcgaac aacagacgat ccataatatc tggtgtcaaa ttttccactt cttgtccagg
    26641 ccgtttcagt aaaactgtct ttaatttccc tatttcagag aaaacgtgaa taggtttatc
    26701 catgttgtgt tgcctccttc tttttgatta catgtatagg atatcctcct tttgtaatca
    26761 ctttcataat tttgtctcat tcaaaatgag acattcctca cattaatatt cgataattaa
    26821 ataattaaac gtttttctat ttttaagcgt aatttattca ttttttattc tgtatacact
    26881 ttcaaaaaaa tatttattca ttgaaaaaat ttttttgaat aaattaaaaa aataaattat
    26941 attatcgttg ttagcgttta ctatatgtat tattgttgtt ttttatacac aaatcattcg
    27001 cttcaaaaca aattattcaa taccattgta tattttttac ataataacaa attatatttg
    27061 taaagtatta aaacttgttt ctaatgttgg tatgttaaaa ctttacaaat tctttaaaaa
    27121 aagtgacaat aaatatagtg aacaataagg agaggacttt ttaatgcgtg ttaataaaat
    27181 cgattttcac ttttcaaaac tcagatatca acctgatttt gaacatttct cggatgaaga
    27241 gttccaacag atcaaggaac atactgttct tcgttcttat aaaaaaggac agatcctttt
    27301 cgacgatggt gatcccagac aacggttgta tatcttgacc aaaggactcg ttcgtttaga
    27361 acgttatgat gaaagtgcaa cttattacta ctatgactat gtgaatacaa ataacctttt
    27421 tcctatgtca ggaatgtttg gagaagagac ctacacttat acagctcaag cgatgactga
    27481 tattgaaaca ttctaccttc ctgtttccta ctatgaaaaa ttagcacgaa aaaatcccga
    27541 acagttgatc tatatgatac aaaaaatttc taaagtagtt gaaatacatg aattgcgtat
    27601 ccaaatcgga ttgacctcta gcgcctttga ccgggtaaaa caaaatttat tcattttgaa
    27661 agaagaattg ggcgtaccaa caaaagatgg tcatatcacc attccttatc cgatcacctt
    27721 aaaagaatta gcagtgaata gcggcacgac acgtgaaact gctggacaag taatcaaaca
    27781 actacgtgat tccgggctgt tagattatga caaaaagcgt tttactttct gtaagacagc
    27841 tactactcca gctatgagag aataacgcga acaaaaataa gcagtgaccc tgataaatat
    27901 cagggtcact gcttattttc ctccctaaaa cttctgaaag atccggcagt tttagatcac
    27961 tggacaagac tcaaagattt tctatgtgtg tttcagttat gtaatattca ctgtttgcaa
    28021 aaaatactgt tagattaact agatgaagcg tcttgtcctc atccgatcta gattattcga
    28081 tattcctcga caataaacga ttactcagtg agggcaatca gaggaacgga taatgataaa
    28141 taagctgtaa aaaatagcaa aataacaata atgattaaaa gtatgtaaaa aatagggctt
    28201 tgacaaaaac gtgtcacagc cctatttcga ttaaacggtg tgtacctgtc aactcttcgg
    28261 tcacaagtca taatgttcat aaacatgagg agctgttttt tgaaattgtt ccttgtgaat
    28321 cagagttaaa cgacaggctt acgaactctt gattaaacgg cgttcaaaag cttgcatacg
    28381 cggtaataag aacagccagg tcaaaaacat gagaagccgt ttttcctggg ctgttcttat
    28441 tacttgatgc agggcagctt tttcacaacc tctttattca gataaaacca agcttggatc
    28501 agcattcaac tgatagctag caaaatttct tttttgcatt tccacatgtg ctgctgctcc
    28561 aatcattgca gcattatctc cacaaagtcg aagaggggga atcactagtt ctacctcagg
    28621 gagtttagct gccaaagcat cctgcaatcc ttcacgcaac ccttgattgg ccgctacacc
    28681 tccagctata atcagttgct tgactggata attttgacaa gctcgaagtg ttttagtaat
    28741 caatacatcg atcacacttg cttgaaagct agctgctaaa tcatttttgt ctagatcttc
    28801 tccacgctgt tgtgcattat gcaccaaatt gataaatgca ctttttaatc cgctaaaact
    28861 gaaatcataa ttatcttcat ggatcatcgc tcgcggaaaa tggtaattat cttttccctg
    28921 atgagctagc tgatcgattt cttttccgct tgggtaagaa agacctaata ctcttccaac
    28981 tttgtcataa gcttctcctg ctgcgtcatc tcttgtctcc ccaatgattt catatgatcc
    29041 atcttcttgc atatagacta attctgtatg tcctccgcta acaagaagtg ccatcaatgg
    29101 aaactggaat ggtttaacca gacgggctgc atagatatgc cctgccatat ggtttacagg
    29161 aataagcggc aattggtgtg cccaagcaaa agccttagct gcagaaatac caatcagcaa
    29221 cgagccgaca agtcctggtc cataagtgac agcgactgcc gataaatctt ctgccgacac
    29281 accagcttct accagtgcat cttccaagca taaggtgatt tgttctacgt gatggcggct
    29341 agctacttca ggtactacgc caccaaaacg tttatgactg tttatttgag aagcaacgat
    29401 gttagataag atctctgttc catttctaac gaccgctaca ctcgtttcat cacaacttga
    29461 ttcaatcgcc agaatcaatt cttcattcat ttcatcgtct ccgtttttaa ctttctgctc
    29521 ataatgatcg catcttccgt cggattgcga taatatgatt tccgtttacc taatatacga
    29581 aacttttctg attcataaag ttttcttgct gcttcattag atagacgtac ttctaaaaaa
    29641 acatgcagcg aatcttttat ttgttccgta atcagtaatt gtaacaaatg ccgtgcatgc
    29701 ccttttcctt gttctgaaac tgcaacagca atatttgtga tctcgacttc atctattact
    29761 ttcgagtatc caataaagcc acagatctgg ttatcttcag ctaaaagcag ataatcagag
    29821 tgaggctgtt ggatgtctgc caaaaactgc attttcgtcc aaggtgaacc atgtggataa
    29881 gcattttcgc taatcatcca tacgcattct gccaagtacg cttcatcaaa atcttttttt
    29941 ctgcaaatca actaatctca ctcattttct aaaagtttta tcatatccaa cgcatcttct
    30001 tttgtttcag tgtaatatct ttttttgatc gttgttgctt gaaaccccaa tttccgataa
    30061 agtctttgtg catcttgatt actcatacgc acttctaatg acatcgtctc acagcgattc
    30121 attatagcaa agttctcgat ttcgtcaata agcagcgaac cgattcgttt acgctgatat
    30181 gccggtcgaa cggcaatatt cgtgatatgg caatctaaac cgaacgctct tgaaccgata
    30241 aaaccaatca ttcttccatt atcaaagata cctagatata gatgaggaag cggtgacttc
    30301 aattctgata taaaggcact ttttgtccat ggcaattcgc cattatagac ttctcgttcg
    30361 acatccagca gctctttgat atcttctgta gtcaattctc ttagtacgta acgacgatcg
    30421 atttgttcga ctgttttttc tgtataaatc attttatctt gaaaaaagct tctggcatac
    30481 gctctaaatt ttttcaacat aactttcgtc tccaggtgtg tgcgtctcca accatttttc
    30541 ttctgcttct actcgtttta aatagcgagg aagaaaagct tgtttctctg caactggttc
    30601 aactaaagca cctaattgag ccacagttac accacttgga atatcccatg ctggaactgt
    30661 attaatcatc gcactaggca atatttcctt tatttcagag aagaatttgt gacaatcact
    30721 cccgacgaaa taaatagctt cattcagctt ttgtagttgt gtgaacaaat cagaagcaga
    30781 aatatgtaca tcttcaagta cagtttctaa tctattttct ttccagcggt atgccccagc
    30841 gtatacattt tttcttcgag catcaaacat gggcacaata atattatcca caccgatgca
    30901 attagccgcg atggttttca gactagatac tcctactagc tctttatcta atgtataagc
    30961 aatcgttttt gctgtcgtta cacctatacg aagccctgta taagaaccgg gaccatcaga
    31021 aaccgcgatt cggtcaatgt cttttggact tatttgaaga tctgcaaaca attggtcgat
    31081 tgcaggcatc agtgttacac tgtggttgcg tttgatattt gtttgtattt gtccaagaat
    31141 ttgttcgtct tctaccacac cgatcgccaa agtttggttt gcagtatcta ttcctaatgt
    31201 aatcatatat ttgatccttt ctgctatgac attctcgcct tccattgtag catacttttt
    31261 tattctgagg atgaaaatac caaaggcaaa actagtacaa taatacatga ttatctgctg
    31321 gcgggcaaat tttgcccctt cctgaaacac aaaaaagctg cggtatcact ccattttccc
    31381 acagcttttc catcttttat ttcgttgatt ctcgaataat caactctgtt tccacaataa
    31441 tctttcttga aaccggtgct ttggaattac ttaattgaag aatcgtctcc actgctagct
    31501 ctcccatcca ttcggtataa acttttacag tagaaagcga gggcgttaca tatttcgcta
    31561 cactgacatc attgaagccc atcacagaaa tatcttctgg taccactaaa cctttttctt
    31621 gaatcgcttt cagtgcgcca atcgctaatg catcattagc tgcaaaaagc gcatcaggaa
    31681 catgcggatt cgtttttaaa tattgcttca ctgcttgata tcctgactcg acagaaaaat
    31741 ctgcttcgat aattggacct tcgtcgtagc ctttttctgc caaaacttgt tgaaatgcca
    31801 taattctggg atcttttagc cgctgatggt ttttcttcgt atattctgtt ccagcaagca
    31861 tagcgatatg ttgcgcttta tgggagacaa agtgttcaat gactttttga acacttgact
    31921 taaagtcgac aactagagag tcgattcctt gagaagtgcc gtcagaatct accaaaagca
    31981 aggcattttg ggatcctttc atttctaata actgagcttc gtcgaatttt cctagtgcga
    32041 tcgttccatc tgccggaaga tcactaatgg aatcccacgt ttctttcaat aaagtaacgt
    32101 ttgcttcttc tgcctttttt tcgattccta ggcgaataga taaataataa agatcttcaa
    32161 gctcttccgt atcgtcgtac cactggatca ggcgaagcgt ttgcttagta tttgctgcat
    32221 ttttacgatg tttcgtataa tttaagcgtt ctgctgcttc aaaaattttt tgctttgtgg
    32281 ctaagccaac ggaaagatca ggatcatagt tgagaactct tgaaacagta gcaggagaaa
    32341 ctcctgccaa ctgcgcaatg tctttaattg ttgccatttg tctctcctcc ttttttacgt
    32401 ttataaaatc gcagtaaatc gttcaaacgc tgcctgtcct ttttcatctc gcttgaatac
    32461 tccagcgtct tccagtacac gtgcaaaaac ctgacctaca gatttttgta cgacatcggt
    32521 gaccgtatct ttcgtcaaat caggatgttc tttttttaat tgttctgccc acggacgatg
    32581 atattcagcc atctggtttt cttctcctaa taagaaatgc tctacttcta ctagttctgg
    32641 tttcaaacga ggtggtaaaa cagcaagccc cattacttcg atcaacccaa tgttctcctt
    32701 tttgatatgt tggacatctt tatgtggatg aaaaatccca tcaggatgtt cttctgaaac
    32761 attgttgtct cgaaggacaa ggtccaactc aaagtaattg tcccttcttc gtgcaattgg
    32821 cgtaatcgta tggtgtggtg taccatctgc tgaaaaagct ctgatagata ctgtttcatc
    32881 cgaatatgct ttccattttt ccaatactga gttagctgct tcaataagca agtttttctc
    32941 tgttgattgc aaacggatca cagacatcgg ccatttcacg actcctgcga tgacttgcgg
    33001 ataatcttct agtttgataa gtttttctat cggtgctttt gccataggaa attcatgacg
    33061 tcctgcctga taatgatcat gagaaagaat cgatcctcca acaattggta agtcagcatt
    33121 cgaaccaaca aagtaatgag gcaagacttc agtaatccga agcagtctag caaatgtttc
    33181 ctttgtgatt ttcatcgggc ggtgttgttc tgataaaatg atcgaatgtt cattgtaata
    33241 agcataaggg gaatattgga atccccagct ttcaccgtct agattcattc gaataatccg
    33301 gtgattggtg cgggctggat agttcaagcg acctctatat ccttcgtttt ccatgcaaag
    33361 catgcaggta ggatagtcta cttttaccgc ctcgcgttct gctgcgattt gttttggatc
    33421 tttttctggc ttagataaat tgattgtgat ttccagttca ccatactccg actctgccgg
    33481 aaatttgatg ttttttgcga tggctcttgt tttgatgtag tcatttttct tacttaaatt
    33541 aaagaaatac tcagttgctt cctctgggct tttcgaatag tgctgtgcaa agaatgcatt
    33601 gacgactgaa ggtggcggtg tgagaaaatc cattaattgc gcttcaaaaa tctcttgttc
    33661 tgctggcaat tctgaaagaa caccattttc tcttgcctta gcgacaagct gatccaataa
    33721 gtctacagat tcttccttaa ctggtcttac ttcaatgctt tctagagcat cttctcctac
    33781 catccctaaa agacgattct gtaaatataa gcggtccatt tccatccatc cgccagcttc
    33841 gatcgcaagt gtggcaaaat cacaaatcgt ttgactgatt gacatatctc attcccctat
    33901 tcttcataac catttggatg gctgacatgc caatcccatg ctgttttgat aatcgctttg
    33961 atatctgtgt attcaggttt ccagcccaga atctctctcg ctttttcact tgaagcgact
    34021 aatcggctag gatctccagc tcttcttggt gctatttctg ctggaatttc ttttcctgtc
    34081 acttctctag ctgcttctag catttccttg actgagtatc ctttgctgct gcctaaattg
    34141 aagaagttgc tttcatttcc ttctttcaag tattccaaag ctaaaatatg tgcagcaatc
    34201 aaatcttcta cttgaacata atctctgata catgttccat ctggtgtatc ataatcgtct
    34261 ccataaacag ccaaggcttt tctttgacca agagctactt gtaaaatgat tgggacaaga
    34321 tgcgtttctg gtgtatgatc ttctccgata gatgcatctg cttttgctcc ggctacattg
    34381 aagtagcgca aagcgacata gcgcatgcca tatgcttggt cacaccactt catcattttt
    34441 tccatcatca atttactttc accatacgga tttttaggat tagctggtgt atcttctgtg
    34501 attggagact ctttcggctc tccataagtt gctgcagtag aagagaatac gattttattc
    34561 acgttgaact cgtgcatgac ttcaagtaag atttgcatac cgtatacgtt gttgttgaaa
    34621 tacatcaatg gtttttcgac agattctcct actaaagagc ttgcagcaaa atggattact
    34681 ccttcaatcg gttccttttc aaatacggaa cgtagaaatt ctttatcccg gatgtctcct
    34741 tcataaaaat gagcatctgg atgtactgct tgtttgtgac ctgtgagcaa attatctacc
    34801 acagctactt gatacccctt ttgaactagc tggtctacag cgtgcgaacc gatataaccg
    34861 gctccgccta gtactaaaat tgtcataaaa aacactcctt tgattagtaa aattgtgttt
    34921 gttgattcta tataatttaa aaaacgaagt ttacttttat ggtgaaaaca aacaaagtaa
    34981 aatttcgtaa attcatatgg taaatttata ataaaacatt tagtaaacat tttcaagggt
    35041 tttttgcaaa ggtttacaaa caaacgtaaa actagccttt ttttctcttt tgttccataa
    35101 tagatataac aaataataaa tgaggtggat tcaatgaaaa aatttgtatc tggaatatta
    35161 gtaggaagtc tggcaacagc cgctgccgtt gctggtttgg ttgcttctgt gaaaaaaaca
    35221 gtgatcgatc caattgacga aaaagaagca atgatcgaag aaaaccgtaa aaaagcaatg
    35281 cgtaaacgcg tttctcgtta ataattattt aaaaatacgc atgaagactt tctaaaaaac
    35341 agataagtca tcatgcgtat ttttatttgt cagtcaatat aagttgtgct attttatctg
    35401 cctgtctcag attccatgga tctgtataag gtctagctac tgctgcagtt agccaatcca
    35461 caccttcaac aggtattcca tagcaataaa agtcagactg gatttcccct gaagcatcaa
    35521 tcacgcgatt cgtacctcgc tcaacatcta tagcttctga atgataactt cctgtattat
    35581 ctgaaaatga aaaagggcga acaagtttgt tttccttcaa attttttatg acaggattac
    35641 ttgaacgaga aaagcttgtt tgtggcaatc gagcttcaat caaatagcga ctgctgattt
    35701 ctttatcttg tagagaaata acatagcggt tgtgcttttg ctgaatatca aatggcggtt
    35761 cgatcaaatg aaaaataccc gcatctatca gtgctgctaa ttctttcgtc cgaatgattg
    35821 gcggaccgat cgttaaaaag ctatttagat gagtaaacca tccccatagt atttctttgt
    35881 attccttagc agaaaaaacg tgccattcaa tagcctgccg gattggatca cgccagtctt
    35941 ttaatgcatc aaatgttgaa gcaaatgctc ctgtgcaatt gcctttttcc gcttctttta
    36001 tctgcccttc aataaatatt cggctagctt ctgaaaaggg ctcattctga taggcaagag
    36061 gagtttctaa atacgaccaa tcccatctat aagggattag tgctggatgc tttccgagac
    36121 actcctctga agagagggag agaaaatcat gctcaaaatt tttctttgga atcggcaagt
    36181 gatattcttc gatgattttc ttgtaataaa acaactcaac gtcttttttc agatagtcaa
    36241 aaaatgtttc gccagtcaaa aatcccgact gatgccattg cttcaggttt tcttttgtta
    36301 gtaaccgtgg ccatgccatt gctccgcctt gcttttgatt tcttcctcga gggtaataag
    36361 ggagccccct tcttgatcca ctgtatacaa tcggttcctt gcctgatgga tgatagacca
    36421 gttttccctt ttcgttctcg aagcgccctc ctcttgatac tgtaaacaat ccgacataat
    36481 caaaaaaact taagcctaga cctcttaaaa agacattttc tttaggcggt atcttcgaaa
    36541 gatctacatc tgcaggatta gaaggaagct gatacagtaa aacatttttc tttgcgtagt
    36601 ctacccacac tctttcttct tctgtctcat cattttccca gtgaccgctt gctaaaacaa
    36661 gctgatcgat agaatagctt tgctgatctg tctgtaaaag ataaccatct tttcttttgc
    36721 ttactttttt tactaaagaa taaacaaact gaatagaagc tggaaattct tcttgcaact
    36781 ttgagaaaaa ccagcgttga tagagtccgt ataaacatcg agtagattgc tgatcttttt
    36841 ccagacgatt gatttcttct ataattagtt gcttattttt ggttaccgtc tgttcgatat
    36901 aatctgtagc aggtccttta ctccattgaa acaagttggg tccctgtgtt accaatcctc
    36961 cactggacaa tgtttcatct gtaaaaagcg tcacttgttg agaaacagaa ttcattaata
    37021 actccggtgg ctgattcaac cgccaaactc gacctccagg accattggga tcgaaaagaa
    37081 aaagttcaag agaatgtctg tcctgattat tatggagaat cctttctgct acacttaatc
    37141 ctctaggtcc ggcaccaatg atccctattt tcatttgcat gcctccattt cgataaattt
    37201 tttcaataaa acagcatggt tctgatgttc attttttgca ccataaacaa aagtaatgac
    37261 tggatgttct ttcataagtt gactgagttt aaaaatagct tgcttctttt cttcttcgaa
    37321 aatcaattct tgctggtatt tctttgcaaa tgaagcaaat cgttctggta catggtcaaa
    37381 agttttgcgt gcttcattac taggtgcaat ttctttcaac cacagatcta actgcgcttt
    37441 ttcttttgaa attcctcgtg gccagaatct atccacgagt attctatagc catcctcttt
    37501 ttcagcatca aggtaaacac gttttaattt gatcatagtt gtttccttct ttctaccttt
    37561 tcgcttagct tatatatgta gataatagca caaaataaaa aaaatgaacg gcacaactat
    37621 ccattgcgcc gttcatgtga tcttggtcaa aatctaatga ttgattcggt ttttaaagct
    37681 gtcatacaat catctgtttt atactttttt acttttgatt tttccagacc atccgtcata
    37741 tccaccctta agtaaataaa tctcttgata acctgcttta cgtaatttat ttgctgtacg
    37801 gatgctcaaa cttttctttt gatcgtaaat atagacaggc tggtcttttc gaatagatcc
    37861 taatgaatct ttcaaaacag tgtaagggat gtttcttgca cctaaaatat gcccagcatc
    37921 aaacacatct ttttcgcgaa catcgattac ttgtgctttt ctcattcctt ctcgaaattc
    37981 ttcttctgtc aaagtcgttg ctgaacgttt ggccattact cgtagataga cttcccaaag
    38041 gatgattgca agcacaatca atagcaaaat gatattaatt acccataaaa ccatgtaatg
    38101 cctccgtttt tttaagcaaa tttcaaggct aatgaggcag caccaatgac accagcttca
    38161 ttaccaagct ctgctaattt gatttttgtt gattctctta cttgcgggaa agtaaattct
    38221 ttaaaatatt tctctacacg gctacgtaaa aattctcctg ctgccgatac tcctccacct
    38281 aacacgatac ttgacggatt taatgtattc cccaagtttc cgcaagctaa acctaagtag
    38341 aagcatacgc gatcaacaac catcaatgca aacggatcgt cttcttgagc catttcaaag
    38401 atatctttac ttgttacttc ttctccgttg tctagcattg ctttcagttt tgaatcccct
    38461 gcgtattctt ctgccaagaa acgacctagg cgtaccacac ctgtagcgct agatacagtt
    38521 tctaaacatc cgcgtttacc gcaagtacat tcgaaccctt caggatccac agtgatatgt
    38581 ccgatttctc ctccagctcc gctcacgccg tgaatcaaat ttccgccagc aacgatacct
    38641 ccgccaacac ctgttcctag agtaacgaat acaacgtctg gatcgttttc tccagcacct
    38701 ttccatcgtt cacctaaagc agcaacattc gcgtcattat cgatagcgaa tttgattcct
    38761 gttcctgcct cgatcagttt tttcacaaat tgaacttctg tccagtttaa gttatacgca
    38821 ccaataaccg ttccagcttc gctgtccacg cttcctgggg tacccatgcc gattccgata
    38881 aagtcttcgg ctttcatatt atataaattc aaacgatgat tgattgattc aatgatttca
    38941 ggaacgatat gcttaccatc atccaaaata ttggtatcga tgctccattt ttgctgaatc
    39001 tctccttctg gtgttaaaat tgcaaatttt gctgttgttc cacctaaatc aatcccaata
    39061 atcttcttgt ccattacaaa tttcctttct ttcggctttc ttcaattcgg tgctctcttt
    39121 ttaatatgcg ccacgctgtc atgtatgtat catgatcaat caaacggcta tcatacagat
    39181 tacgcaattc gatagtcatt aattcaatgt catagatgcg tgcacccaca tagataaaga
    39241 tgccaaattt tttgaacagc tgctgtacat catataagct ctccatcttt aagcacttcc
    39301 ttcatattat acaagtaaac catatttttt taaacccagt aaaatacata ttacaaaaag
    39361 aaatacaaaa actagtgtag aaagaatcct ttggtgtatc gaatagcttg tctgttgttt
    39421 cggtagaccc aaaacattcc ctaacactaa tccgccaatt agcccaccga catgtcccca
    39481 aacatctaca gaggtatcca gaagaccaaa aacaaatgtc aacacaataa ataaaagaaa
    39541 atgtctgact agctgctgga tcgctgggtt atgtttaaaa tgaaacccta agataaacaa
    39601 cgcaccgaac aaaccgaata tcgaagtact tgcaccacca gacagaacat tcgcttcgtt
    39661 aaaagcaaag cttgctgtat ttcccattat cccgctgaac atataaatca agaaaaaacg
    39721 ccaatggcca tagattgcct cgatttgctg ccccataaaa tacagtatca gtgagttcat
    39781 tacgaaatgc atcagtccaa aatggatgaa gattggtgtc actaaacgcc accattcatt
    39841 gaagtgaaca agataaggac catacattcc ggcataataa gggatctcaa gtcgcggaaa
    39901 taattccatc atgaggaaga ccgctgtctg tatccctaaa aaagcatagg tccataacgg
    39961 tcgtcttaac catgcacgca attttatttg ctgttgataa ttcatgaaaa cctcccattt
    40021 cattttagtc aataaacaat tgttggatct tctgatcaaa gctctccggt tgccattgtt
    40081 cattcaattg ttcacgaaaa acaaggctac atgttttttt atgaaaatta tttaaatacc
    40141 ggtcgtaata accaccgcca aaaccgattc gataaccggc tctattgtag ataatacctg
    40201 gtacaatgag gagatcgatc atctccggca aatagagctt ctctgattgt ggctcaagaa
    40261 caccaaaact cgaacgtaca agaacggact gttcatccat ttcataaaac gccatctgac
    40321 gtttcggcaa agttttaggt acaactattt tcttttgttc tttttctgct cgttggataa
    40381 ccggctgtgt atccagttca aattcattcg ataaagtcgt ccctatcact tttgctgact
    40441 tccagtactc gctggcgaat agctgtttat agattcgctg ttctttttcc tttttcttgc
    40501 cacttttggc cagatttttc agcttttcga ttcctttccg gcgtaatctt actttcaatt
    40561 ggtccaaaaa ctcacccttc cttctctcat aaaatggtat aggaaaaaaa gaaaaatagc
    40621 aatcgaactt tcaaataaat gcataaatag aataaaaaga agacctagaa atgattggcc
    40681 ttcctttttt aatgaatttc aactgttcag cgcgtgtttt tgtctgataa aaagtgcata
    40741 cagaaaatat ggcgcaccaa aaagggcaat caaaattcct gtaggtactt ccccacttgg
    40801 tagaatcact ctagcaacca tatctgcact aagcagaaaa atggaaccga acaaaccgct
    40861 cagaacaaag gtccagttat tttctttacg tacgactagc ttcgcagcat gaggagctag
    40921 tagtcctaca aaagataaac tacctgtcac cgctacacta ccgcttgcca aagcaacagc
    40981 taacaacaaa aggatttttt gacttttagc cacgttaagg cctaatcctt gcgcgcgttc
    41041 ttgaccaaat gatagcaata caatcctctg tgcataaagt cctcctagcg gaattaagat
    41101 aaccgcccat ggaagcaatg cccaaacata aggccagctc gcaccccaga ttgatcccgc
    41161 taaccatgca ttcacaaatc cataattttc cttagataat tggatcgtgc atagcaatgt
    41221 taatgcagaa aggccggcat taacggcaat accggacaat aagattcgat tcatacccaa
    41281 aaagccattt cgatcatagg ccgcaagata gacacagcaa gcagctaaaa caccacctag
    41341 aaaggctaca actagcaata gaaacggcag cgaatagtgc gaaaagaaac ctaaataaag
    41401 catcactaaa aatcctgctc cggcattaat gcccaatata ctagaatctg ccaattcatt
    41461 tcttgttact ccttgcaaga tataaccaga aacgccaaga caagctcctg ctaataaact
    41521 gatcagtaat cgaggaactc gaaattctct aacaatcagc gccaaagaag atgattcttt
    41581 ccctatgaac gtggcaaaaa gctgatccag gtaaataaaa ggcgtaccaa tcattaaact
    41641 acctatagac aggatgacaa gtacaaaaag caagaaatag aacgtccaat atattttttt
    41701 caccgttgtt ccctccttac ttgtatcagt aaaaacggaa cgccaatcaa tgcaatgact
    41761 aatccaaaag gtgtttcaaa agggggattg atcatcctcg ctgtaaaatc cgccaacata
    41821 accaatccac cgccaactaa aaaagagaca ggtagaacat aacgatagtc cgttccaacc
    41881 attccgcgaa caactggcgg aaccaacagc ccaataaatg aaacaggtcc gactaacgaa
    41941 acggcaatgg ctgctaacac tgcaactaga cagaaaacaa tcaaccgcgt tcgtttagga
    42001 tgacttccaa gagctaatgc atgtgtttca ctcaaatgaa tcaaagatat tgcttttcct
    42061 aatgaaaaag aaaccaaaac agcaagtata tataaaggaa acaatactgc taattgtttc
    42121 catgtgatat tggcagctcc gcctacaaac caaaaagcaa gatcctgctg cagattaaag
    42181 aattgggtaa gtgcttggct gatagcagta aaaaaagaac taatagctac gccagctaaa
    42241 atcagctgta aaggattcat gcccattttc gaaaactgca aaaaaccaaa tacgagcaaa
    42301 gttacagcaa aagaacctgc caatgacatt agaaacacag aaaaatcaga agctttaggc
    42361 caaaaagcaa aactaagggc cattgccaac gaagcacccg cgttgattcc tagtaagcct
    42421 gaatctgcta aaggatttct tgtcactcct tgcatcaatg caccgctcaa tgcaaaacaa
    42481 ctccctacaa gaaatgctcc cgccacacga ggcaaacgaa tatttcgtat gatttggtga
    42541 ctttgttttg atctatcaaa atcaaacaac gcctgccaaa aatctgcttt ttccacagtc
    42601 gctgcgccat ttgaaagagc aacaaaaaaa ataatcaaaa gaacaaaaca gaccaaaagc
    42661 aggagtctat ttttcttcat agtcctcata attgatcctc ctgctctttt ggcaacaaat
    42721 cataggttag aaaaactggt ttatttgttc ttggaagcgt gacaatcgtt gcatcaatct
    42781 caaatatttt tttcatacac tcttttgtga tcacttcttc aggtgtacct tctgtgatca
    42841 acttaccgtt tttcattgct aataaataat ctgaaaaacg tgaagcatga ttaatgtcat
    42901 gaatcgacat caagatcgtt gtttgtttca tttgattgat ttcagtcaat aactgtagga
    42961 tctctaattg gtgtgccgga tctaaaaatg ttgtcggttc atccaagatc aagatatctg
    43021 tttcctgagc aagcgccata gcgatccaga cacgctgggt ttgtccacca gacagcgttg
    43081 cgatatcccg catacgaaat ccagctagac ctgtagcatc caacgcccac tcaattgctt
    43141 catgatcttg cgtgtccatg ccactgaaca gtttttgata agggtatcgt ccgtaagata
    43201 ctacttcttc tactgtcata cctgtagggt gttcactagt ttgtgctaat aatgcaattt
    43261 tttttgcaag ttcttttgaa ctgtatgtag agatatcaga gttattgaca atgatctttc
    43321 ctgatttcac aggtagtata cgggtaaaac ttttcaataa agtagatttt ccacttccat
    43381 ttggcccaat caaactagtg attttccctt caggaatcgt aacagacatg ttttcaatga
    43441 tttttttgtt ttcgtagccg gctgcaatgt cagctgctct taatctcgtc atttcaccca
    43501 tcctttcgct gaaaatcatt ctcaattatg acgctgtttc aacatttcgt caagcgctac
    43561 tttcatatct atagccaaat gaagcggttg acagcgttcg aaatatcagg aataataacc
    43621 aatgagaaag attctcaatt atgttaggag gaaagaaatg aaattaaaaa caaaagtatt
    43681 cacattatct agcatattgc tgctggctgg agtactgagc gcttgctccc cctcttcaga
    43741 taaagaaaca gctacaactg ccaattcgac gacttcatcc aatagtactc atacagtcac
    43801 agatacactt ggacataaag tagagattcc aaacgcgccc aaacggatca tcggcagtta
    43861 cttagaagac tatctgattg cactagggga aaaacctatc gcccagtgga ctgttggcag
    43921 tggttccatt caagattatc tgcaagatga tttaaaggat gtcccaacga tttcttatga
    43981 ccttccttat gagaaagtgt taagctttga gcctgatttg ctgttgattt cttcttccgc
    44041 tactgtcgaa ggcgggaaat acgaacaata tagcaaaatc gcgccaactt atgttgtaaa
    44101 aaacggaaca gatgtcacat gggaagaaca actaaaagat gtcggcaaag ctttggcaaa
    44161 agaaaaagag gcagaaaaaa tcatttccga ttatcaaaaa tccatcaaga aaactcgaga
    44221 agaactagca gataaaatcg agaacaagac agctgcagtg ttgtgggtga ccaacaactc
    44281 agcctttatg gtcagcaaaa atcggtcaag tggaagaatc gtatacgacg atctggaatt
    44341 tggtgttcct gatctagtgg aagaggtctc caaaaaagcc acttctgact ggtctgctgt
    44401 ttcctctgaa aagctagctg aattagatgc tgactacatc atccttgtga acagtgacaa
    44461 agatgctgcc atgttcaatg aaccaagctg gaagaatcta aaagcagtga cagacaatca
    44521 tgtactgcaa ttcggacctg aatctagttg gctatataac ggacctattg ccagtcagga
    44581 aatggtcaat gatatcaaag aaaaactaaa ttgattttaa ctaaaaaaag catcttcacg
    44641 attagtcgtg agatgctttt tttcttatta acaaactaga cgcatagatt ttattcttct
    44701 tttgaagcaa ccctattttt tactctttcc catttttgaa aacgatgggc atatagattt
    44761 tcttgatccg ttatcccctc atactcctct ataagggcga agtctgaaaa atcaatattc
    44821 ccaatatacg tatcgccttc aaacgtgcta tcgatcaatg ttcgccagat ccgaccagtg
    44881 taaggaagaa gttcttgaaa aatccgacta ccacccgaaa catagatatc ttctgagatc
    44941 gtttgactat acgacaaaag ttcatcgatc gaatgcatta cttccgcatt ttctttcgtg
    45001 cgaaaatttg gttgcgttgt caacacgatg atatggcgat aaggaagtga aagatccccc
    45061 attccttcat aggtctttct tcccatcact aaaattcgat ccattgtatg ttcgcgaaag
    45121 aaacgcatat catttggcaa tcgccatggt aacaaaccat ttttgccgat cagaccattt
    45181 ttatcttgtg cccacatgga aataaacata ttatccgctc cttatgattt tagatgtttt
    45241 gagataaaaa aagtctcaat tctttgacca gcaaggaatt gagaacttta aaaacattat
    45301 tttgtttcac ggtgcaaagt aactttgcgt tcgcgtgggc aatatttttg tttttccaaa
    45361 cgatcaggat tgttacgttt gtttttgctt gttagatagt tacgttcttt acaagaagta
    45421 cactctaaag tgatgtttac gcgcatgttt ttccctccca tttttacaag aatcctctaa
    45481 gatgactctc agacttgatt atcttaccat gattttttct agattgctag tgtttttcac
    45541 gattttgtta agtaaaacta cttgacgata aatacaacgg ttttacttct caaacaaaat
    45601 ctttttcttt ttgtataaat acccttacac ttgtttatat agattatgtt ttttaataaa
    45661 gggggatact aatatgccat ggaacatgaa ggactttcct gcatcaatga aaaacttaga
    45721 taaattgaca agaaaaaaag caatcgacat cgcaaatgca ttattagatg aagggtaccc
    45781 tgataaccgt gcgatcccaa ttgccattga tcaagcaaaa aaatggtatg aagatgctag
    45841 tgaatcagaa aaacgaactt tcgaaaaaga aaaaaatcca agcaagacgg atgaacacga
    45901 tacgaatcct cgtgctggaa aactgcttga ttcagatgtg atcgtagaat atgaggaaga
    45961 acaatggatc gtgaaatcta aaggggcaaa aaaggcaagc aaccattttg atacaaaaaa
    46021 agaagcaatc gaaaaaggaa agcaagtagc acaaaacaaa gaatcaactt tgttcattta
    46081 taaaaaagat gggacaaaag aaaaagaaat cgattattga acatatgtaa aggggttgtg
    46141 acgaaaatcg tgtcacaacc cccttatgtt cgaaacaatg gtgttcctct gccaactccg
    46201 aaccataagt cataatatct ataaaacggg aagagctgtt ttttgaaatt gtttcttatc
    46261 actcagtgtt aaacggtagg agaaaacctc ttttttattg atatttgatt ttcatcaaac
    46321 agtcacatag tcgattgctt ctgcttgcgg aatcgtttca tctacaaagt agactttata
    46381 ccatgtcaag aaactgaaga ttgtccagat ttttctttgc tcttctttac gtccttcgtg
    46441 atggtcatct agcaacttca tgattttttc ttgatcaaaa aattcttttg caaaatctgc
    46501 ttcgaataat gctttgactt gttcgtagcc gtgttcttct ttcaaccaag ctttgattgg
    46561 cacagggaat cctaatttca cacgattcga ccattcttcc ggaagatgtt tgttcgcagc
    46621 ttgtctgaaa atatcttttg tgttgttttg attcaataaa aacttacttg gtatttgttg
    46681 agccaatttc atgacttcga tatccaataa aggtactcgg acttccaaag aacttgccat
    46741 agaaagttta tctgccttta acaagatatc ttttggcatc cattgatgaa gatcgacata
    46801 ttgcatctta ttgacttcat ctttgattcc ttctgttttc tcgtaatgaa cagtcatgat
    46861 ttcatccaca gatggtgctg tttgatattt tggtgttaac acttctgatg cttctgattc
    46921 ttcgaacact cgagcatgac cgataaaata ttcttttgca ggagcaagtg attcatataa
    46981 atggatccgt ccatggaagt ttttcatttt tccgatttta cgtcctaaat tatagcgtgt
    47041 tccttttggt aattttttca atccttgagc aatcacacgg atgaattttg aattcgtatg
    47101 gaatccatac gtttggtatc ccgcaaacag ttcatccgcc ccttctccag attggactac
    47161 ccgcacactt tgtgaagcaa gatttgctaa aaagtacaaa ggtacgcaag aaggatttga
    47221 atcaggttca tctaagtgat actggatcaa agggaatgct ttgaacgaca tgtctccgtc
    47281 gatcactgct gctgtattat ctaagtccaa tagttcggtt agttttctgg cttcaatcgc
    47341 ttcattatag gttttatcat caaacccgat tgagaaagaa tgatctggtt tcaatacaga
    47401 ggttacataa ctggaatcaa ccccgctgga taagaaagaa ccaacttcta catcactgac
    47461 cgtatgtgct tcaatagaag cttgaacggt ttcgtcgatt ttttcgatcc attcttgtcg
    47521 ggaatgcgtt tcttttgttt caaaatctgc atcccaatat tgctgaatgt ctatttttcc
    47581 atctttatac gtataataat ggccttcagg caaacgatag acatctttga agaatgtttc
    47641 gccgtttaat ggagaatatt ggaaagtcat ataaggtttc aacgcttctt tgttcaattc
    47701 tttgttaaaa tcaggatgag gcagaaaact tttgatttct gaaccaaaca taaatgttcc
    47761 gttcatttct gcataataat atggtttgat cccaaagtgg tctcttgcac cgaataactc
    47821 attcttttca ttatcccaaa tagcaaaagc aaacattccg cggatctttt gcaataattc
    47881 tgttccccat tcttcgtaac catgcaaaag gacttctgta tctgcatgtg tttgaaaaac
    47941 gtggccagct gcaatcaatt cttctctcaa aggctggtaa ttatagattt cgccattaaa
    48001 aataatgatc tttgtccgat cttcattgta aataggctga gtaccgccct ctaagtcaat
    48061 aatacttaat cttctgaatc ctaaagcaac atgtttatcg atatattctc ctgaactatt
    48121 aggtccacgg tgaacgattc gatccatcat tgtattaata attgtttttt tgttgtcctt
    48181 gtcgttaaca aaacctacaa taccgcacat ttaactttca catcctaata taaaattact
    48241 gtttatttca ttcatatgca tcttatcata gaataaatag cggacgaata ttttctctct
    48301 tacaatttcg tcacgtgaaa acaaaagatg aaagtttctg tttttacaga aaataaagtc
    48361 ccaatatcta atttaccatg ttttcttttt tgaggctacc ttattctctt cgtgttaaaa
    48421 aaatattagt ggatgctatt tccaaaaaaa ccagcaaaaa aagacacgac ctaaagatcg
    48481 t
//
LOCUS       DASHXG010000018        47224 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.018, whole genome shotgun sequence.
ACCESSION   DASHXG010000018 DASHXG010000000
VERSION     DASHXG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.018"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(29..1261)
                     /locus_tag="U2R59_001145"
     CDS             complement(29..1261)
                     /locus_tag="U2R59_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEM8965552.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="U2R59_001146"
     CDS             1516..2085
                     /locus_tag="U2R59_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965553.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="U2R59_001147"
     CDS             complement(2263..2703)
                     /locus_tag="U2R59_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEM8965554.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="U2R59_001148"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="U2R59_001148"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEM8965555.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="U2R59_001149"
     CDS             3657..4580
                     /locus_tag="U2R59_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEM8965556.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="U2R59_001150"
     CDS             complement(4805..5044)
                     /locus_tag="U2R59_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965557.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="U2R59_001151"
     CDS             complement(5049..5468)
                     /locus_tag="U2R59_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8965558.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="U2R59_001152"
     CDS             complement(5695..6933)
                     /locus_tag="U2R59_001152"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8965559.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="U2R59_001153"
     CDS             complement(7040..7675)
                     /locus_tag="U2R59_001153"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965560.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="U2R59_001154"
     CDS             complement(8017..8652)
                     /locus_tag="U2R59_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965561.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="U2R59_001155"
     CDS             9164..10306
                     /locus_tag="U2R59_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEM8965562.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="U2R59_001156"
     CDS             10299..10505
                     /locus_tag="U2R59_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEM8965563.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="U2R59_001157"
     CDS             10584..11777
                     /locus_tag="U2R59_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8965564.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="U2R59_001158"
     CDS             11982..13121
                     /locus_tag="U2R59_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEM8965565.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="U2R59_001159"
     CDS             13114..13914
                     /locus_tag="U2R59_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8965566.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="U2R59_001160"
     CDS             13914..14741
                     /locus_tag="U2R59_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8965567.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="U2R59_001161"
     CDS             14719..15453
                     /locus_tag="U2R59_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8965568.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="U2R59_001162"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="U2R59_001162"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEM8965569.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="U2R59_001163"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="U2R59_001163"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEM8965570.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="U2R59_001164"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="U2R59_001164"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEM8965571.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="U2R59_001165"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="U2R59_001165"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEM8965572.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="U2R59_001166"
     CDS             19038..21071
                     /locus_tag="U2R59_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965573.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="U2R59_001167"
     CDS             21115..22395
                     /locus_tag="U2R59_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HEM8965574.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="U2R59_001168"
     CDS             22605..23411
                     /locus_tag="U2R59_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965575.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="U2R59_001169"
     CDS             23423..24643
                     /locus_tag="U2R59_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965576.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="U2R59_001170"
     CDS             24633..26219
                     /locus_tag="U2R59_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8965577.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="U2R59_001171"
     CDS             26258..28396
                     /locus_tag="U2R59_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8965578.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="U2R59_001172"
     CDS             complement(28764..29747)
                     /locus_tag="U2R59_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEM8965579.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="U2R59_001173"
     CDS             30125..31516
                     /locus_tag="U2R59_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEM8965580.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="U2R59_001174"
     CDS             31532..32572
                     /locus_tag="U2R59_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8965581.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..33676
                     /locus_tag="U2R59_001175"
     CDS             32591..33676
                     /locus_tag="U2R59_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEM8965582.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33709..34671
                     /locus_tag="U2R59_001176"
     CDS             33709..34671
                     /locus_tag="U2R59_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEM8965583.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            34664..36091
                     /locus_tag="U2R59_001177"
     CDS             34664..36091
                     /locus_tag="U2R59_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEM8965584.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            36093..37163
                     /locus_tag="U2R59_001178"
     CDS             36093..37163
                     /locus_tag="U2R59_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965585.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            37150..38571
                     /locus_tag="U2R59_001179"
     CDS             37150..38571
                     /locus_tag="U2R59_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEM8965586.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            38584..39591
                     /locus_tag="U2R59_001180"
     CDS             38584..39591
                     /locus_tag="U2R59_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8965587.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            39603..40607
                     /gene="neuB"
                     /locus_tag="U2R59_001181"
     CDS             39603..40607
                     /gene="neuB"
                     /locus_tag="U2R59_001181"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HEM8965588.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            40604..41752
                     /gene="neuC"
                     /locus_tag="U2R59_001182"
     CDS             40604..41752
                     /gene="neuC"
                     /locus_tag="U2R59_001182"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HEM8965589.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            41725..42402
                     /locus_tag="U2R59_001183"
     CDS             41725..42402
                     /locus_tag="U2R59_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEM8965590.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            42392..43534
                     /locus_tag="U2R59_001184"
     CDS             42392..43534
                     /locus_tag="U2R59_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEM8965591.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            43547..44524
                     /locus_tag="U2R59_001185"
     CDS             43547..44524
                     /locus_tag="U2R59_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8965592.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            44524..45432
                     /locus_tag="U2R59_001186"
     CDS             44524..45432
                     /locus_tag="U2R59_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEM8965593.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            45433..46185
                     /locus_tag="U2R59_001187"
     CDS             45433..46185
                     /locus_tag="U2R59_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEM8965594.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            46190..47137
                     /locus_tag="U2R59_001188"
     CDS             46190..47137
                     /locus_tag="U2R59_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HEM8965595.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        15785 a         7469 c         9073 g        14897 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    32821 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    32881 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    32941 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    33001 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    33061 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    33121 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    33181 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    33241 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    33301 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    33361 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    33421 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    33481 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    33541 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    33601 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtatata
    33661 tagtagagat cattaaaaat gttcaagata ttttaggagt gattattttt gaaaatatgt
    33721 tatttgatat tggcatacaa tgatattggc aacttaaaga gattggtcaa tcgattgaac
    33781 gaaaatgcag tttttattat tcatatagat aaaaaaactg atatagaacc atttattgaa
    33841 gcatttaaat catatgataa tgttgaattt ttatgtaata aaaaccgtgt taaaatttat
    33901 tggggtggtt tttccattgt acaagcagaa atcaatttag taaagagagc attacaaaat
    33961 gagaaatatt taaaatatgt attattatct ggtgctgatt atccaatcaa agataatgag
    34021 tatatttata attattttaa aaagaatagt tcagtggagt ttattcgtgg aatagatcta
    34081 gatcaaatta aacataaaga attttattat aaacatatag atgtatatca aaaacatgat
    34141 tatcctagaa ttaataggaa taacacaact gcatttaaaa tttttagagc tataattaat
    34201 cgttgtctga ggatgattaa acttccccca aaaattagac accataaatt tgatttgtat
    34261 catggttctc aatggtgggc tttgtcgaaa gaatgcctaa cagaattaat acaaatgtat
    34321 gaacaaaatc aacaagacta cctgaatttt aaaataggta tgtttgcccc agatgaaaaa
    34381 ttttttcata cacttttttt taattcctcg ttcaaaaata aaaatgttat tggaggacca
    34441 gatttaccac ttgaattgaa aaatattgaa gaaactactt tacaaacttc gaaattagca
    34501 aatattcata ttattgatcc ttccatgaac aaatggtttg atgaaaggga tatagatcaa
    34561 ataaaagaaa gtgaaaaatt atttgtaaga aaagttaaat cggattactc tgataaacta
    34621 ttaaatagaa ttgataaaga aattttgaaa gttggaaata tagatgaata gaatagtacc
    34681 tgttttagag aagagtttat taagtcgaga tgcgtttcga gtaataaatt taatcatttg
    34741 tctgctttat tttatgccta gtacttttaa tgtaactaat atcccgatga aaatagcttt
    34801 tgcttggggt ggaattatag ttttgtatga ggtttttata aagaaaaatt tttttaaaat
    34861 gcgtttttct tggctactga ttggagcaat gattagtttt atcttaacta taatcattaa
    34921 cagagaaaat tttttaattc catctattta taattttgga tatttgctga ttactttgat
    34981 agtaattttt cctgcagact tttcacaaag tgaagaggaa aaaaagaaaa aaatggtgta
    35041 ttttaataat gttttcatta tcataatttt tttagctgcg ctaatatcta tctatcaatt
    35101 tatttttttg atttcttatc atgtcccaac aggaacgcca ggattacttg caagacaagg
    35161 ttttattgaa catcggttat ttggtgtcta tacaagtcca aatgttggag ctatgtttgg
    35221 atatacttct attattttaa gtttaattag tgtattaatt tcaaaaataa caaaaacgat
    35281 tcgtgttttt tatatgatga attttatcgt acaaatattt tatattacac tttcttcgtc
    35341 tagaggtgcc caggtagtaa tttgttcttt tttagtatta tttcttttgt tgtttgccaa
    35401 ttcaaaattt agaaagagca ttagagaagt actacctgta aaaatcaaat ggatggtaag
    35461 catattatta gttctattgg tatatttttc ttttggtact aattatgcta aggatttttt
    35521 agcaacaatt cctgtatcga ttgatagaaa agtagaagtt atagagtcaa atgaatcaga
    35581 taaaactcca cttccagaaa aagaagtaat attacagcat tctagtgata actccgaaat
    35641 ttcagctggt cgttttacga tttggaaagc tgcgcttaaa gttataagac caactttgtt
    35701 atttggttat ggagagaccg atttctatgg gaatagcgat gcaaaatttt tgaaaaaagt
    35761 agatcttgat actacagatg tgaatgaact aaaaagagca catggaaaca tgcataatgg
    35821 atttcttcaa gtacttgtat caagtggtat aattgctttt atatgtatct atgctttcta
    35881 tgtgttaaat atctttagtt tactcaaaac attttttaga agtaaagtga attatgcgtt
    35941 tcttggtatt gttttaattt ttatactatc tatttttata gatgaaatgg tggaggctca
    36001 tgtacttttc aataagcgcg atgtcatttc aattgttttc tggtattatt tgggaagcat
    36061 ttcttacttg tatttaaaaa aggagaatta atatgaagac agctttcatt gcttggactc
    36121 ctttacattt gattaatata ttaaatgttt atcaaaattt ttaccgagaa tcaaaaggag
    36181 atttatttat ttattctgaa tttgaaaacg ctagaagata tagtgagcgt ataaaagaat
    36241 tagggctatt taatgatgtt gtttttgtga atcaccggaa aatcggttct tcctttaaac
    36301 gtaaaattaa cttgttaact aaccataatc aatttttctc ggatgattta tccgtttatg
    36361 atgaaatttt tatacagggg gaaaattatt tcacaaaaat acttttctcc aatgtttaca
    36421 aaaaaaatcc agatgtaaaa ctaaattata tagaagatgg tttgggtact tatttgaaga
    36481 agagtatatt ttcaacaagt aaaaacgttc aaagagtttt taaaatatta aataaaaata
    36541 gcatcttcaa aaaaaaaatt gacgattatt ttgtctattg tccggaattg ttactttatg
    36601 atgtaaaaaa tataaaaaaa attcccaaaa tagatgaaaa cagtaaattg atgaaaaaca
    36661 tacaatcaat ctttgggata gaagaagttt ttgtcggaga taaatgtatc ttttttgatc
    36721 aacctttatt atctgatggt tatggcatag atgaaacaga tattttcgct aaagtaaata
    36781 gtatattttc tggaaaaaaa gaaactttaa ttaagcttca tcctagagca aggacaaatc
    36841 gttatggtga aaaaaacata ttgaattcca gtttaccgtt tgaagtcttg ctacttgaaa
    36901 atgacttctc ttcaacactt ttgattagtc ctatatctac aatttctttt tcaccatcta
    36961 tgatgtttga aaagacgatc aactctatta tgttggctaa attaatttta aatgaatata
    37021 cagcattatc tgaagataaa aaagaaacat tgacaaatat tgttcttttc tgtgaacatt
    37081 ataaccgtct atcagaagaa aaaattttac tcccagaaaa ctgggcagaa ttaagaaagt
    37141 tggtagagta tgggattatt taacacactt tccaagtcaa aattagttaa gtccagtttc
    37201 tggtatacta tagggaattt ttttattaag ggaatttcat tcataactat tcctattttt
    37261 gtaaatatta ctactcaagc agaatatggt ttgattaata atttcacttc atttgtatca
    37321 attttttcga ttcttgttgg gctaagccta aattcggcaa ttaataatgc aagttttgac
    37381 tataaagatg acataaatga atttatgtca tcggtacttt ctctagctac actttcgtta
    37441 attgtgttct tattaatagg gaacatatat tttttgtttt caaatgcttt ttttgatatg
    37501 aaccaacttg tatttaattt gatgttatta caaagttttg ctagttttgt aattagttat
    37561 atccagtctt attttacgat taactttaac cattttaaat atttgatttt atcttttata
    37621 tctacttttt tgaatattgc aatctctgta gctttgatgc agacattata ttttgatgat
    37681 aaatatgttg gcagagtagt cggcggaaca ctgtcatttg tgttgatagg tttagtaatt
    37741 tatttaagaa taatgataaa gggtgctcat ttttttgata aaaaacagtg gagatacgct
    37801 ttaaaaatct ctttgccgct aatcccacat tccttagcaa atatagtttt agcacaattc
    37861 gatagaatta tgattaattc ttatttaggt cctgctgcgg ggggaatata ttcctacatt
    37921 agtaacatag gtattattct aagcgtaata tggatgtcta ctaataacgc ctgggttcca
    37981 tggttctatg gtgagatgag taaaaataat gaaaaaaaag tgaagaaagt tagtaactat
    38041 tatttagtag tctttacttt gattacgatg attgtaatgg tagtttcgat tgatttagca
    38101 aaatttatgg ctccgaaaga ctattattct gggttatctt tagtggttcc gataacctta
    38161 ggctatttct ttcagttttt atatagttta ccagttaatg ctgaatttta tgagaaaaaa
    38221 acatcgttta ttgcgattgg tacagtagca agtgctatag ttaatatact attaaacatg
    38281 attttcatac ctaggttagg aataattgct gctggataca caaccgtatt tacgtatttt
    38341 ttacttttta tttttcatta taatatcgct aaaaaaatta cgaataaaca attatttgac
    38401 acaaaaaaaa tatgtatcat aataattttt gtatcaattt tttctttgat acttcatatt
    38461 ttaatcaatc aaatgttgat tcgttacgtt ttgacatcat tattgataat tagtttagtt
    38521 atatattttt taaagattaa gaatcgaatt atagatgact ataattcata ggaggagata
    38581 taagtgttta aaggaaaaac aatattagta actggcggaa ctggttccat tggaagtgaa
    38641 attgttcgtc agcttttaaa atatgaacca aaagctatca gaatttatag tagaggtgaa
    38701 gaaaaacaat tttatatgca acaagagctc tcaaatcaca ctaatttgag atttttaatt
    38761 ggtgatatca gagactctca aaggattgat tatgcatgtc gtgatgtgga tattattttt
    38821 catgctgccg caatgaaaca cgttccagca agtgaatata atcctatgga agctgtaaaa
    38881 acaaatgtga tgggaactca aaatgtaata gatgcagcga tcaaaaataa tgtaaaacat
    38941 tttgtaggta tcagtacaga taaagtagtg agtcctacta acaccatggg tgcgacaaag
    39001 ttattgagtg aaaaattaat aatagctgcc aatcagtata aaggaaaaac agaaacaata
    39061 ttttcttgtg taaggtttgg aaatgtcatg gggtcaagtg gatctgttat tcctcttttt
    39121 agtaaacaaa taaaaaacaa taaagatatt actttgacag atgttgatat gacacgattt
    39181 atgatgtcaa taccggatgc tgcaagatta gttctgtctg ctgctatgaa ttcaaaattt
    39241 ggagaaacat atgtcttaaa aatgccggca atcaatattt taactttagc tcaatcatta
    39301 ataaaaatat ataatgatac acatgatgaa aaatatagag gtgaaataaa agttgtaggt
    39361 atcaggccag gagaaaaatt atatgaagag ctaatgacta cagacgaaat tgaacgctca
    39421 tatgaaaatg ataaaatgta tatcattcca ccacactatc atgctactga cgaactgtac
    39481 aaagattatg aaaaaattaa aatcactgca tactcttcag atgcaacaga attaatgagt
    39541 ggacaggaat ttattagaat cgcaaaagag aataatgtcg tgacttggta aggagtttta
    39601 tgatgaaatc agaagtatat gtaattgcag aaattggtgt aaaccataat ggaagtctag
    39661 atttagcttt agaaagtatt gataaagcta aagaatgtgg agctaacgcg gttaaatttc
    39721 aaacatttaa aacgaataag ctagtttcca aaaaggctcc aatggcaaaa tatcagaagg
    39781 ataatcttaa agaggacagt tctcaatttg aaatgctaaa aaaattagaa ttatctcaat
    39841 ctgattttat tagaataaaa gattattgta tacaaaataa aattgatttt ttgtctactc
    39901 cttttgatga agaaagtgca gactttctaa aacaaattgg tgtacaagga tttaaaattg
    39961 gctcaggaga tttaacaaat ttaccttttc ttagaaaaat agatatgtat gggttgccag
    40021 ttttattatc tacaggtatg gctgatattc atgaggtcag tgaggctgta gattgtttca
    40081 tagatagtcc agttactatt ttacattgta cttcaaatta tccggctagt tctgaagata
    40141 ttaatttatt ggcgattaac acattaaaag aaatgttcgg gatacccgtt gggtactccg
    40201 atcattcatt gggatatgat gttggtattt gtgctgttgc gatgggtgct aaggtaattg
    40261 agaaacattt taccttggat aaggaactac ctggtccaga tcataaagct tctttagatc
    40321 ctcaggaatt tgcagatttt gtaaagcata ttagaaacac tgaaatattt ttaggtgatg
    40381 gtgttaagcg agcaatgcct tctgaactta gtacaaaaga agtatcaaga aaaagcctag
    40441 tggtcactga gaatttaaat gtgggagata ttcttacaga gaaatctctt acaataaaac
    40501 gtcctggaaa tggaatagct cctaagtttt tatatcaata tattggcaaa aaagttaaaa
    40561 gaccaataag tgcagatagt gttctgcttg aggaagatgt tgaatgaaaa aaatacttat
    40621 agtaagtgga acacgagctg attatggaat atataaacct gttgctgaga atttactaca
    40681 agataattgg gatgtatcat ttgttgtttc tggaatgcat ttatcccata aatatggatt
    40741 tactaaagaa ttgatcttag ctgacggatt tagaattagt ggagaagttc aaagtttgtt
    40801 tttagagaac aataagggaa acatggctcg gtctgtggca ttagagataa atggtttcac
    40861 aaatatattt gaacaaacta gccctgattt tgtattatta ctaggggata gaggagaaat
    40921 gttggcagct gcgatagctt gtttgtatct tggaatcaaa acagcacata ttcacggagg
    40981 cgaagtgtct ggtactgtag atgaatcaat aagacatgcc ataacgaaaa tagcatctgt
    41041 tcattttgct gctacggaaa aaagcaaaga gcgtttaata aaaatggggg aagattcttg
    41101 gagagttttt cccgtcggag ctcctagaat agatactatt ttaaataata gattacctag
    41161 ttttagagat ataaaagaaa aatatcatct aaaatttgaa aagaaaaaat acgttttgca
    41221 agtatttcat ccagttgtaa ccgaactaga aaatatagaa aaacaaattt tagctttgat
    41281 caattcaatg gaacaacaat ctcaaccaat tatttgcatt ttacctaata gtgatgctgg
    41341 tagcgaaatt atcagaaaaa tgtaccagaa atatttaaaa acggatatta tttatattac
    41401 gaatttagag ccggaggaat acctgactat attaaaagag tgcaaattta tgatcggaaa
    41461 ttcttcttct gggataattg aagctgcatc attcaaaata ccagtaataa atttaggaac
    41521 cagacaaaat ggacgagaac aatctaaaaa tattataaat gcaaatctaa atgaaaatga
    41581 aattgaaact gctttgaata aaatacaaga tcctcagttt ataaaaagct tgaaaaatgt
    41641 taagaacatc tacggtgacg gcaacagttc tagaagaata acaaaaacat tgaatcaaat
    41701 attgaatgat ggggaagata ttaagtggat tcaaaaacaa atagcttatt aaaatatact
    41761 agtgatccat acattattat tggggctggc ggacacgcaa aagtcattat tgaaacctta
    41821 agattagaaa ataagttaat atatggattt tttgatgata agcaaaataa aatgcaagat
    41881 ctgaaatatc ttgggaaaat aaacgaattg aatagctggg cggatagcaa aaaaaaaatc
    41941 tataaattta ttgtagctat tggtgactgt gtagtaagaa aaaagattat aaaaaaattg
    42001 aatatgccaa gtgagcaata tggaatagct gttcatccaa gtgctatagt ggcaaaagaa
    42061 atttcaattg gttatggaac tgttattttt gcgaatgctg taattaaccc agatgctgta
    42121 attggagagc atgctataat aaacacaggt agcattgttg agcatgattg tagaattaat
    42181 aactatgttc atttatctcc aggtgtatgc ttagcgggtg gagtacatgt aggtgtagga
    42241 actcaaatag gaattggttc tcaatgtatc cagatgaaga aaattggatc ttggtgtatg
    42301 ataggcgcag ggagcactat tgttaaggat attccctcac attccttagc ttatggcaat
    42361 ccagctaaaa ttaagaaaga aggaattaat tttgaattct agaattttat tatcaagtcc
    42421 tcatatggga ggaacagaag aaaaatatgt tgctaaggct tttaaagata attggatagc
    42481 gccattaggt gaaaatgtgg ataaatttga agaaagtatt acaaaatata ctggttctaa
    42541 gggcggagct tctgcgttaa gttcaggtac agctgccata catcttgcct taagactgct
    42601 taatgttgga aaaaacgata ttgtctttgc tccttcattt acttttatag ctacagtaaa
    42661 tcctatttta tatcaagggg ctgtaccagt gttcattgac tcagaaccta atacatggaa
    42721 tatgagccct gttgcactag agagcgcatt agaagaagct gaaagaaaca accaattacc
    42781 taaggcaatc atcgtagtga atttatatgg tcaaatggct gattatgaac gaattttagc
    42841 tattgcaaac caatttaatg ttccagtgat agaagatgca gcggaatcgt taggttctac
    42901 ttataaggga atttcgtcag gcttatttgg gacaattggg atctattcat ttaacggtaa
    42961 taagatcatc acaacctcag gtggaggagc tctagtgtct agtgataaaa aatatgttga
    43021 gcattcaaga tttttagcaa cacaagcaag agatcaagca ccgtattatc aacatagcga
    43081 aataggttat aattaccgtc taagcaatat ttctgccggt atcggacgtg gacaaatgga
    43141 agtattgaat gatagagtag ctaaacgaag agaaattttc aatcgatata aggaagcttt
    43201 ttctggaatt gatagaattg aaatgatgcc agaagtggat ggcatggtgc caaatcgttg
    43261 gttgtctact ttaacgatca atgattataa ttctattgat caagtagtta acgtaataaa
    43321 taaactaaat gaaaaaaaca ttgaaacaag agctttgtgg aaaccactac atttgcaacc
    43381 agtatttcaa ggggtaaaaa tgtattacca tgataataat cttagtgtgt cagaaaagtt
    43441 atttaatagc ggcttatgct taccttctgg aagtaatatg acagatagtg aacaagaatt
    43501 tgttattgat gagtttaaaa aaatattcaa gtaggtgtga tattttatga acataggaat
    43561 tattggttta ggttccatgg ggaaaagaag acttagactc attcaagaac actttaatga
    43621 tattttacta tgtggtgttg atactaatga ggcgagacga aaggaagttg aaaaggaatt
    43681 tggaatacca acttataata gtctaacaga ggcaaaaaat ttgtttgaaa taaattcagt
    43741 ttttgtttgt acatccccta taacccatga atttattata aaagaggctt taaatttaga
    43801 ttgtaatatc tttacggaaa tcaatttatt aaatgaatat tatgatgaaa taatcgaagt
    43861 agctaaaaag aaagatagat tactttatct atcttctaca tttttgaaga gaaaagaaat
    43921 tcaatatatt aagtctaaag tgacgcataa taaaaaaatt tcttatcaat accatgtagg
    43981 acagtattta cccgactggc atccttggga agattatcgc aatttttttg tttcaaacaa
    44041 aaaaactaat gggtgtagag aaatattcgc tattgaatta ccttggatta tagatacatt
    44101 tgggaaagtt aaatcgttta ctgtaatgac ccagaaatta tccaatcttg atattgatta
    44161 ttcggacagt ttcactctta ttattgagca tgaaactggt atagttggaa ctttaagtgt
    44221 agatgttgtt tcaagagtag ctaaaagaaa tttaactata attggtgaaa agattttaat
    44281 agaatgggaa ggtaacccgg attctctatt ttcatggaat gaagaaactt ctagtatgac
    44341 agatattcaa ttgtacgatg aggttatgca tgataataat tattcacata ctattattga
    44401 agatgcatat ttagaggaga ttaaagaatt tttcacgctt ttggaaaaga aaatggaacc
    44461 ccaatatact tttgaaaaag ataagtatat tattaactta attaacgaca ttgaggtaaa
    44521 ttaatgatga aagtaatttt ttttgggtta gggtcaattg gaaagagaca tctaaaaaat
    44581 ctaataagct atggaaaaaa gaattctatt aattttgata taacagctta tagtagcagt
    44641 ggaaaaaaag agtttgaaga aataacgtat attcaaaata gagacgattt ggatacacat
    44701 tatgatatag cttttattac aaatccgact tttaagcatc tggaaacact aaatgtaatt
    44761 gttgaaaaag ttgattacat atttttagaa aaacctgctt tttctgagag tattgatctt
    44821 actcaatata attatgatta caaaaatatt tatgttgctg ctccactgag gtataaaaat
    44881 atcatggaag ttgttcgtaa tagtattcaa agtaaaaaag tatattctgt aagagctatt
    44941 tgttctactt atcttcctga ttggagaaaa ggtactgatt atagaaataa ttattctgcc
    45001 tttaaatcta tggggggagg agtagaatta gactgtatac atgaattgga ttatattata
    45061 aacctatttg gtttccctaa atcagtaaaa aaacagtttg gtaaatattc gaatcttgaa
    45121 attaacagta atgatttagc aacatatata ttgagatacg atgataaaat tatagaaatt
    45181 catttagatt attttggaag agttcctaca agaaaatttc aattgtttac tttagatgaa
    45241 tgtatcaatg ttgacttatt aaataataaa ataagttttg aagaaaacat tgttaaagaa
    45301 atgcctgaat ctgctaatga tatgtatgag aaggagttga aatatttctt tgaaaacgta
    45361 gtaacaggca aagaaaactg gaatgattta tatcatgcaa acgaagtatt gaaaatagct
    45421 gaggagaaat aaatggaaat tttatttact atttgtggta gagctgggtc taaggggttt
    45481 aaaaataaaa atttgaaata tttggcagga aagcccctag tccatttcgc tttagcaatg
    45541 atagatatct atcaacaaaa acatcctgaa cataattgca cgacttgttt gaatacggac
    45601 agtaatgagt tagtagaatt gacgactaag ttaaatccgt ctgtgaaaat tgtagaacgt
    45661 aaacctgaat tagctacaga tactgtaggg aaaattgaag tgatacgtga ttcattctta
    45721 caactagaaa gagaagataa tatatttgat ttaattatag atttagattt gacttcacct
    45781 ttacgtgaag tttctaatct tgaagaatta atagatgaac atctaaaaaa tttagataaa
    45841 gacgtctact tttcagttgt ttctgcaaga cgtaatccct attttaatat ggtaaaaaga
    45901 attgaaaatg aagttactat agttaataaa tcaagataca catctaggca acagacacct
    45961 gaagtttttg aaatgaatgc ctcaatgtat tcttttaaac ctgaatttct aaaaaaaagt
    46021 aattatattt ttgatgggca atgtgggata ataaaaatga gagattatct aattttagat
    46081 attgatagtg aagaagattt taaatggtta gaatttttgt ttcctaaatt tttagaagat
    46141 tcttcggagc ttcaagatat ctataattat ttatatcgga ggtaaaagga tgagctgtta
    46201 tcttatcacc ggtggggctg gcttcattgg ttctacctta gccaatcatt taggagaaga
    46261 acatgtggta atcgtcgtcg atgacttatc aatgggaaaa gtagaaaatc ttgatatgac
    46321 gaaaaatatc acttttattg agggagatgt cgctgagaaa tccttgatgg aagagatcat
    46381 gaaagctaat aaatttgatt atatctttca tttagcagca gttgctagtg tggcagattc
    46441 agttgcccga ccagtagaaa cacatcgtgt gaattttgaa agtgtattaa tgattttaga
    46501 attgatccgc aagtatcaac ctgatttaaa acggatcgtg tttagttctt cagcggctgt
    46561 ttatggggat gaaccgactt taccaaaaaa agaagagtcc gtgattcgcc cattgacgcc
    46621 ttatgcggtt gataaattcg ctgcagaaca atatgtgcta gattattgtc atttatatga
    46681 tgtacccggt agcgcagttc gttttttcaa tgtctatggt ccaaatcaaa atccgaattc
    46741 tccatacagt ggtgtgattt ctattctcgt agatcgctat aagaaacaaa tcgtaggaga
    46801 agcaacttca tttacattat ttggtgatgg aagccagtct agagactttg tttatataga
    46861 tgatgtaatc caagcattac ttttagttgc gaatgaggaa gctgcactgg ggaaacaatt
    46921 caatgttgga acgggtaaag caaccacact tttggaattg attcatgcaa tcaatgaaat
    46981 tctcggtgta gaattgacac ttgaatacaa agaagagcgt tcgggtgata tccatgactc
    47041 tctagcagat attactaaga tccagtcaat tggctatcaa ccgaaatatg gtattttaag
    47101 tggaatgact aattatttga aaactgaaat caattaaaac atactaagat aagattagag
    47161 ggtaaattca ggctctttgt caataaggac tgatgagttt tgtaaaatca aatctgggat
    47221 agaa
//
LOCUS       DASHXG010000019        45883 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.019, whole genome shotgun sequence.
ACCESSION   DASHXG010000019 DASHXG010000000
VERSION     DASHXG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.019"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            9..731
                     /locus_tag="U2R59_001189"
     CDS             9..731
                     /locus_tag="U2R59_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8965596.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            789..2828
                     /locus_tag="U2R59_001190"
     CDS             789..2828
                     /locus_tag="U2R59_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HEM8965597.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2937..4088)
                     /locus_tag="U2R59_001191"
     CDS             complement(2937..4088)
                     /locus_tag="U2R59_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEM8965598.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4242..4772)
                     /locus_tag="U2R59_001192"
     CDS             complement(4242..4772)
                     /locus_tag="U2R59_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HEM8965599.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4871..5221)
                     /locus_tag="U2R59_001193"
     CDS             complement(4871..5221)
                     /locus_tag="U2R59_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEM8965600.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="U2R59_001194"
     CDS             complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="U2R59_001194"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEM8965601.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="U2R59_001195"
     CDS             complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="U2R59_001195"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEM8965602.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7624..8286)
                     /locus_tag="U2R59_001196"
     CDS             complement(7624..8286)
                     /locus_tag="U2R59_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8965603.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8470..10116
                     /locus_tag="U2R59_001197"
     CDS             8470..10116
                     /locus_tag="U2R59_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HEM8965604.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10107..11189
                     /gene="uxuA"
                     /locus_tag="U2R59_001198"
     CDS             10107..11189
                     /gene="uxuA"
                     /locus_tag="U2R59_001198"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEM8965605.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11297..12850)
                     /locus_tag="U2R59_001199"
     CDS             complement(11297..12850)
                     /locus_tag="U2R59_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8965606.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12998..14286
                     /locus_tag="U2R59_001200"
                     /pseudo
     CDS             12998..14286
                     /locus_tag="U2R59_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14412..15491)
                     /locus_tag="U2R59_001201"
     CDS             complement(14412..15491)
                     /locus_tag="U2R59_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8965607.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15594..16034)
                     /locus_tag="U2R59_001202"
     CDS             complement(15594..16034)
                     /locus_tag="U2R59_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8965608.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16091..16501)
                     /locus_tag="U2R59_001203"
     CDS             complement(16091..16501)
                     /locus_tag="U2R59_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HEM8965609.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16681..17115)
                     /locus_tag="U2R59_001204"
     CDS             complement(16681..17115)
                     /locus_tag="U2R59_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8965610.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17215..18063)
                     /locus_tag="U2R59_001205"
     CDS             complement(17215..18063)
                     /locus_tag="U2R59_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEM8965611.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18452..20218
                     /locus_tag="U2R59_001206"
     CDS             18452..20218
                     /locus_tag="U2R59_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEM8965612.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20320..21579
                     /locus_tag="U2R59_001207"
     CDS             20320..21579
                     /locus_tag="U2R59_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8965613.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21726..23027
                     /locus_tag="U2R59_001208"
     CDS             21726..23027
                     /locus_tag="U2R59_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965614.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23030..23881
                     /locus_tag="U2R59_001209"
     CDS             23030..23881
                     /locus_tag="U2R59_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965615.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23894..24709
                     /locus_tag="U2R59_001210"
     CDS             23894..24709
                     /locus_tag="U2R59_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HEM8965616.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24860..26026
                     /locus_tag="U2R59_001211"
     CDS             24860..26026
                     /locus_tag="U2R59_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8965617.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26256..26903
                     /locus_tag="U2R59_001212"
     CDS             26256..26903
                     /locus_tag="U2R59_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEM8965618.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26987..27931
                     /locus_tag="U2R59_001213"
     CDS             26987..27931
                     /locus_tag="U2R59_001213"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEM8965619.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            28066..29517
                     /locus_tag="U2R59_001214"
     CDS             28066..29517
                     /locus_tag="U2R59_001214"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEM8965620.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29538..30374
                     /locus_tag="U2R59_001215"
     CDS             29538..30374
                     /locus_tag="U2R59_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEM8965621.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30374..31033
                     /locus_tag="U2R59_001216"
     CDS             30374..31033
                     /locus_tag="U2R59_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8965622.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31159..31848
                     /locus_tag="U2R59_001217"
     CDS             31159..31848
                     /locus_tag="U2R59_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965623.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31854..32810
                     /locus_tag="U2R59_001218"
     CDS             31854..32810
                     /locus_tag="U2R59_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HEM8965624.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32854..33366
                     /locus_tag="U2R59_001219"
     CDS             32854..33366
                     /locus_tag="U2R59_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8965625.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33622..34170)
                     /locus_tag="U2R59_001220"
     CDS             complement(33622..34170)
                     /locus_tag="U2R59_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8965626.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34259..35440)
                     /locus_tag="U2R59_001221"
     CDS             complement(34259..35440)
                     /locus_tag="U2R59_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEM8965627.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35676..37184)
                     /locus_tag="U2R59_001222"
     CDS             complement(35676..37184)
                     /locus_tag="U2R59_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEM8965628.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37343..37534
                     /locus_tag="U2R59_001223"
     CDS             37343..37534
                     /locus_tag="U2R59_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965629.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37737..38654
                     /locus_tag="U2R59_001224"
     CDS             37737..38654
                     /locus_tag="U2R59_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HEM8965630.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38647..39720
                     /locus_tag="U2R59_001225"
     CDS             38647..39720
                     /locus_tag="U2R59_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965631.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39868..40386
                     /locus_tag="U2R59_001226"
     CDS             39868..40386
                     /locus_tag="U2R59_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965632.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40367..40759
                     /locus_tag="U2R59_001227"
     CDS             40367..40759
                     /locus_tag="U2R59_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEM8965633.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40835..41770
                     /locus_tag="U2R59_001228"
     CDS             40835..41770
                     /locus_tag="U2R59_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEM8965634.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41903..42682
                     /locus_tag="U2R59_001229"
     CDS             41903..42682
                     /locus_tag="U2R59_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEM8965635.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42675..42992
                     /locus_tag="U2R59_001230"
     CDS             42675..42992
                     /locus_tag="U2R59_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEM8965636.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43236..44846
                     /locus_tag="U2R59_001231"
     CDS             43236..44846
                     /locus_tag="U2R59_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8965637.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            45003..45851
                     /locus_tag="U2R59_001232"
     CDS             45003..45851
                     /locus_tag="U2R59_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8965638.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        15235 a         8277 c         8822 g        13549 t
ORIGIN      
        1 tatctatttt gttactgctt acattagtag ttggctattt ttcgattgag tttatccatg
       61 gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt agagccgaaa agtatcccta
      121 ccacactaaa tgtggctttg attggttcag atgctcgttc gaaagacgaa aacggtcgct
      181 cggattcact tctggttgca caatacaacc agaaaacaca acaagcaaaa ctgatctcta
      241 tcatgagaga ttcatatgtc gatattccag gttacggaat gaataagata aatgcagctt
      301 actcttatgg gggagttgat ttattaaatc aaacattaaa ggaaaatttc aaatttgaag
      361 ctccctatta tgcaagtatc acatttcaag attttatcga ttgcgttaat gaactgtttc
      421 ctggtggagt caagatcgat gcagaaaaat ctctagattt agatggcgta tatataaaca
      481 aaggagagca agtgatggat ggtaatactt tactccagta tgctcgattt cgggaagaca
      541 aagaaggaga cttcgggagg atcagaaggc agcagcaagt gatcaaagct atctctcagc
      601 agctgaaaga cgtaacttca atattcaagc tacccaaagc ggttgggaaa ttacttggta
      661 gtatccaaac gaaccttcca gaaagtgtgc ttctggattg tggtatggat ttcctcaaag
      721 acatatgtta gaataaacag gtataaatag tgaaataaag gaatgacaag caagagaagg
      781 aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg aacaggcgct tatattgccg
      841 gcgcagtgat cttaatagca gctgcgggtg gcggttattt ttactaccag cactatcaag
      901 aaacccaagc agtagaagct ggagaaaaga cagttgagca atttgtccaa gctttgaaca
      961 agggagatta taacaaagct gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat
     1021 tatctgaaaa agagatctta gataaatacc agaatatata cggtgctgct gatgtcaaag
     1081 gacttcagat atcgaatcta aaagtagata aaaaagacga ttctacttac agtttttcat
     1141 ataaagcaaa gatgaatacc tcattaggtg aattgaaaga tctttcttat aaaggaacat
     1201 tagacagaaa tgatggtcaa accacgatca actggcaacc caacttggtt tttccagaaa
     1261 tggaaggaaa tgacaaagta agcctgacca cacaagaagc agcaagaggg aatattatag
     1321 atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa acaattagga gtcgttccaa
     1381 gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa agcgattgct tcctccttcg
     1441 acttaacaga agatgctatc aatcaggcga tttcacaaag ctgggtacaa cccgattact
     1501 ttgtcccatt gaaaatcatt gatggagcaa cgccagaact tccagctgga gctaccattc
     1561 aagaagtaga cggcagatat tatcctttgg gtgaagcagc tgctcagctg attggttacg
     1621 tgggagatat cacagcagaa gatattgata agaatccaga attaagcagt aatggaaaaa
     1681 tcggtcgctc aggtttggag atggcttttg ataaggatct tcgtgggaca acaggtggga
     1741 aattaagcat tacagatgca gacggtgtag agaaaaaagt tctgatcgaa catgaagttc
     1801 aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca
     1861 gtctaggagg aaaagctgga tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg
     1921 cgcttgctag ctctccaagc tatgatccaa acaaaatgac aaacgggatc tcacaagaag
     1981 attacaaagc ttatgaagaa aatcctgaac atccattcat cagccgattt gcgacaggtt
     2041 atgctcctgg atctacgttt aaaataatta cagcagcaat cggtctcgac aacggcacta
     2101 tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg gcaaaaagac agttcttggg
     2161 gatcttttca aacaacgcgt gtcagtagtg atgtatcaca agtagactta aaaactgctt
     2221 tgatctattc cgataatata tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat
     2281 ttcgtacagg cttagataaa ttcatttttg gtgaagacct tgatttgcca attagtatga
     2341 atccagcaca aatttctaat gaagatagct ttaactcaga tatcttgcta gctgatactg
     2401 gatatggaca gggcgaactt ctaattaatc ctatccagca agcagcaatg tattctgttt
     2461 ttaccaacaa tggcacactt gtctatccta aattgattgc agataaagag acaaaagata
     2521 agaagaatgt catcagcgaa acagcagtac aaacgatcgt gccagatctg agagaagttg
     2581 tgcaagatgt aaatggtaca gcacattctc tttctgcttt agggattccg ttggcagcga
     2641 aaactggtac agcggaaatc aaagaaaaac aggatgtaaa ggggcaagag aacagtttct
     2701 tgtttgcttt caatcttgat aaccaaggtt atatgatggt cagcatgttg gaaaataaag
     2761 aagatgatga ttcagcaacc aaacgagcat cggaactatt gcaatacctc aaccaaaatt
     2821 atcaataaaa aattgctttt taagtacagt aaaaggactg tggcgttatc gtcacagtcc
     2881 ttttttcaaa taaacggttt tcacgatgtc tctttcacaa cttctttttg atttactcac
     2941 acttcataaa ctttttttgt aaaatatttg agaacaagtg gagaaataag tgtacttaat
     3001 aaaatcacga taactaaagg tgaatagtac tgtggttcga tcaattgact ttgctgtcca
     3061 atttgtaaaa tgatcaaagc catttctcca cgcgaaatca taccagcacc gaccatcaat
     3121 gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat aacctccaag caatttggtc
     3181 aaaatcgcta caagcgtcaa tatagaaata aagagtagtt gttcactaaa gtcagaaaaa
     3241 tcaacttcta atcctacact gacaaaaaat actggtataa atactgcata tcctaaagcc
     3301 tctacattgt ggtatacttc ttctttaacc tttgtctgac tgacagctat cccagcaaaa
     3361 aaagcaccaa tgacagagct aagcccaaca agatccgcta cgtaagacat tcctaaacaa
     3421 ataactagcg atacgatgat aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt
     3481 aggaaaggcg caatccattt gactaataag aaaataaaaa caaaataaat tagctgttca
     3541 atcaaaacaa gcggtaaaga agcattgcta gaagcttccc ccgttagaaa agataggctg
     3601 aaacttagaa ctaaaacgac taaaatgtca tctaccacag aagcacccaa aattgttgat
     3661 ccttcttttg tattcactac gtttagttct tttaatactt ctactgaaat actgacagaa
     3721 gttgccgcaa gaataatccc aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg
     3781 cctgtcaacc agccaaaaac aaccgggaag atgatcccaa gcaaagcaac gaacatacca
     3841 ggtcggaaat attttttcaa aagagataaa tcactttcca gaccagctaa aaacattaat
     3901 aagatcacac caatctccga aaagtcatgg actagaatat caggtttgac ccaattcaat
     3961 ccagcttggc ctagcaaaac accaacaagt aattgtccaa tcactgctgg gatacctaat
     4021 ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata tcaggcataa aataccaata
     4081 aattccattc tcatcattcc tttgtataaa atatagcccg aacttagcat aacatacatt
     4141 attgaaaaaa taggaaaata tactcacaaa aaaaccaaca atccaaaaga tttttttgga
     4201 ttgttggttt ttatacggtc tattttaata actaaaaatg attaacgtat agtcattttt
     4261 cttattctga tgaaattgat aatctcctgg atgcccatga aaatcaaaat aaagccgaat
     4321 atttggaata gaagcatcaa acttttgaat ggattgaaca ataagacgaa tccgccaatc
     4381 aacaacagaa tactactata aacactccaa cttttagctt ttgtattcat gctgaagaac
     4441 aactggaaca agctgttgat gataacagct aatccaagaa gaatcggcag gatagaaacg
     4501 attgcaggtg caaaagcata gacgatcaga gctaagatca ggaaaaaaag accactgaac
     4561 agaccgatac tccaagaacc tgttttcctt ttaaaacggt aagcctcaaa aagattcaac
     4621 aacccaagca aaacaagata ggcggtgatc agataaccga taaaatgaaa aacagcagaa
     4681 gggtttagca caatcgcaat cccagaaata atataaacag cagctcttaa taaggcgtat
     4741 ttttgaatat tttgtttaat cgtctcaaac atataagaaa acctcctttg acttatttta
     4801 acgtgaacta gtcattttac caaattaaat gttacaaaat gagcgaagga gaagaatatc
     4861 tctggaaaaa tcaacttctg aggatctttt ccattttttt gccttttgct agctcatcga
     4921 tcattttatc taaataacga atttctttca tcaagttatc ctcgatgtct tctactcgta
     4981 caccacaaac aacacctgta atcaaggaac gtgaaggatt ggggacaggg gcttccgcaa
     5041 aaaattgttc gaaagtcact tgtttttgta gttgatattc tagttctgtt tgggaataac
     5101 ccgtcagcca acaaatgatt tcatctactt cctcttttat acgatctttt ctctccgctt
     5161 ttgctacata cataggataa acgcttgcaa aacttgtcgt aaaaatacga ttttgcgcca
     5221 taatcagtca cctttctttt tttcaaatta tttactactt atagtatata agaaaaagag
     5281 aagaaaaagc gattattcaa aaaaacaaaa aggattgtga caaaattctt gtcaccatcc
     5341 ttttttccgc tctctgactt tttacaatct tcatagctca agtgcgcatc agataatcga
     5401 atgctcctaa agctgcagta gctcctgaac ccattgaaac aatgatttgt ttgtatggac
     5461 tatctgtaca atcaccagct gcgaaaacgc cggggatatt cgttgcgcca tttttctcgg
     5521 tcactatttc atttcttgga ttcatttcga tcgttccatc tagccaatcc gtattaggga
     5581 gtaagccgac tagaatgaat actcctgaaa cagctagtgt atgcatctcc atcgtacggc
     5641 gatcgatata ggagagagat tctacctgat tcgtaccgct gatttctttc gtcgctgcat
     5701 gtttgataac agtgacattc gcaagagaga ctagtttatc ctgtaagatt tgatctgctt
     5761 ttaattctgg taagaattct agaacatata catgttttgc taacccagcc aaatcgattg
     5821 ctgcttcaac accagaatta ccaccaccga taacagcaat ctcttttcct ttaaataaag
     5881 ggccgtcaca gtgtgggcaa taagcaattc ctttattttt aaactctttt tcgcctggta
     5941 cattgataga acgccagtgc gcacctgtcg cgatgatggc ggtttttgct ttaagtgata
     6001 taccgttagc taagccaata ttaataaaat gttgctcttt atttaaggaa acggcctgtt
     6061 gattcatcat aatgtcgata gggtaactac gcacatgact ttctacttgc tgcatcaatt
     6121 ttggaccttc tgtgtaagag gtaccaatca tattttcaat ccctagtgtt tcaacgactt
     6181 gtccgccgaa agaatcagcg acaagtcctg tacggattcc tttacgtgct gcatagatag
     6241 ctgcactact agctgctggt ccaccgccaa ttactaatac atcataaggt tctttttcaa
     6301 acaactcttc ttcaatcaaa gggccagtga ttttttcaac aatttgttcg atcgtcatgc
     6361 gtccgctact aaattcttct ccatttaaaa acacagttgg cactgccatg atttttttat
     6421 catcgatttc tttttggaac atcccacctt caatcatcgt atgagtaata tttggattta
     6481 atacagctaa tatattcaat gcctgtacaa cgtcggggca attatgacaa gtcaagctaa
     6541 cataactgtc aaaatgcaat gtttgtgtta tttttttgat tttaagactc aaagattcac
     6601 tgattttcgg tgcccgtcca ctaatttgta acatagccag taaaaaagag gaaaattcat
     6661 gaccgagggg gataccagca aaaacgattc cactttcttt gccaactgga ttgatagaaa
     6721 aactaggtgt gcgcatcgaa tctctttttt cccaagagat tttaggagac atttctgcta
     6781 tttccttcgt aaattcagct agtttttgac tattttcact attatccaaa ctaacagaaa
     6841 aaacaatagg agattcaatc agtgctaaat attgttcgag attttgttta gtttctttgt
     6901 ctaacatatc caccacctaa atctttccaa caagatcaaa acttggtttc aatgtttcgc
     6961 cactttcttt ccattttgcc ggacaaactt cacctgggtg ggtacgtaca tattgagcag
     7021 cgcgaatctt atcaatcagt gcactagcgt cacgaccgat tccatctgca ttgatttcca
     7081 tagcttgaac gattccgtct ggatcaataa taaatgttcc tcgctgagct aatccttgct
     7141 cttcatccaa aacatcaaaa atacgagaaa tctgatgaga cggatcaccg atcatcacgt
     7201 attcgatttt accgatagca tctgatgtat catgccatgc tttgtgagta aagtgggtat
     7261 cggtagagca agaaaagact tcaacaccta aagatttcaa tgtactgtat tgttcttgta
     7321 agtcttctaa ttcagtagga caaacaaaag taaaatcagc tggatagaag caaagaatac
     7381 tccagttccc cataagatct ttttcactga cttctaaaaa ttctccttga tgataagcat
     7441 gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat agtaaaacct ccaataataa
     7501 ttatttattt ataattattg taatttagtt ggagttgcaa agtcaatgga tattttgtta
     7561 tttaataaag attactcaaa aacgaaggtt aattataaaa atagaagagg tcgcaagaaa
     7621 atgctactgc tggaaatact cgggataacg ttgagtaaca gtttcctgtt ctttcagcat
     7681 catgtgtaag tgcaatcccg tttgaaatcg agcttcttct ggttttttat caactaaagc
     7741 cttgagtaaa tcataatgtt gttccatgat cgtttcccat ggaagcccct gaatggtcac
     7801 tcgtaaccag cggaaacgtt ctaaatgggt attatggtca tctaaccagt tccaaacttc
     7861 ttttcttcct gcaatttcga aacaagcttc atgaaataaa ttatctgcac ggaaaaaagc
     7921 gcgttcgtca tttattttga ctgctttttc ttgttcttct aaaatcgttt ctagcactat
     7981 tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg atttgctctt ccaactgttc
     8041 tcggacaaag cgagcatttt ctgcagaaac aagattaatt ttggaaacat acgtaccact
     8101 ttgaggtatc gtatacacga gttcttgctg acgtagttga atcaatgctt cgcgaatggg
     8161 agtccggccg atagcaagat gttcctccag tgccttttca gatattttcc ttccaggttc
     8221 taagtcagca tagataattt gtttacgaat cgcttgataa gcttgtgatt gcaagctgct
     8281 tttcatcttt attcctccaa aatcatttct atgaacgtag tataacagaa gaggtctgaa
     8341 aaacaatctg gtatgtcaca ttaactagta aatttgtata aatagtaaaa ttttggttga
     8401 catagcgatt tttattgtat aaaattcact tgaatacaaa aactaatatg ttagtttagg
     8461 aggggaaaaa tgattgattt aaacaactgg aggaacttta tccctgaatt atctcaaaaa
     8521 gaagtagaaa tacctcattt tgaccgtgca tcattaagag aaaatggaca aaaaaatcct
     8581 gtctggatcc atttcggtgg cggaaatctt tatcgaggat ttcatgcaga aatcgctcaa
     8641 cgtttagcgg atctaggcga attgtccact ggtgtcattg tttgtgaaac attcgatgaa
     8701 gaaataattg aaagggctta ccaagatttt gatgatttga ttcttgaagt ggtcatgcca
     8761 agcagtggag agttcgtcaa acgtatatta gctgcgacag ctgacagtct gtattgtcat
     8821 ccagattgtt ctgaacactt tgataagatg attcgacact ttgaaaatcc tagtttacaa
     8881 ttagttactt ttgctattac tgaaaaaggt tatcgattga aagatacaaa taataaatat
     8941 ataggaccga ttgcagtcga tataaaaaat ggtccaaaga agccatcaca tacaatgagt
     9001 attcttgctg cgctacttta taaacgtttt ttatctggag cttggccgat tgcacttgtc
     9061 tctacagata atttttcaca aaacggtagt caattacgta cttctttgct aacgatcgca
     9121 aaagaatggc aaaaggaagg ttatgtacaa aatacattta tccaatactt atcgaatgaa
     9181 gaaattgttg cgtttccatg gacgatgatt gatcgtatca ccccgaatcc ttccttgtca
     9241 gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt cgattttcca aaccgcaaaa
     9301 ggaaataata ttgctccatt tgtcaataca gaggacatcc attatttaat catggaagat
     9361 cattttccca atggacgtcc gaaattcgaa aaagctgggg tattcttgac tgatcgtgca
     9421 acggtagata aagcagatac gatgaaggtg acgacttgcc ttaatccttt gcatacgtct
     9481 ttagctatta tgggttgttt actggggtat aggagcatag ctgaggagat gaaagatcca
     9541 gatttatcgc tgctagtttc tgaaatcggg tacaatgaag gcctcccagt tgtggagtct
     9601 ccaggtatca ttgatccaaa gatctttctg gaagaagtaa ttactgtgcg cttttctaat
     9661 ccaaatattc ctgatatgcc tcagcgaatc gccacggata cctctcaaaa ggtggcgatt
     9721 cgttatggtg agacgattaa aaaatatatg gaaatagaag ttaaagaccc gcagacactt
     9781 gtattcatac cattgactct cgctgcttgg cttcgatacc ttattggcat tgatgatcaa
     9841 ggaaaaccat tcatcccgag tccagaccca ctattgacag actttcagca taagctttcc
     9901 gatattcaac tgggtacgca agatacatca catattcatg agaaaatggc tcctattttg
     9961 tcaaataaag aaatttttgg tgtagatctt taccaagcag agcttggcag aaaaatagaa
    10021 gaaatgttca tcaagatggt agcaggaccg aatgccgtac gaaaaacatt acaggattac
    10081 ttacaagaac atggaggaaa tttatcatgg aaatgacttt tagatggtac ggatcacagg
    10141 aagaaaagat taccttagat gaaatcagac agattcctgc ggtcaaaggg attgtaggca
    10201 cattgatgga tataccagta ggagaggtat ggcccaggga gaggatcaaa gaactaaaag
    10261 aagaaattga gtctcgtggg ttaacactaa aagtaattga aagcgtcaat gtgcatgatg
    10321 ccattaaaat tggattacct tcccgtgagc agtatatcga aaactataag cagacaatcc
    10381 gaaacttggc agaatatgga atagaagtca tctgctataa ttttatgcct gtatttgact
    10441 gggtgaaatc tgaccttgac taccgcttag aagacggctc atccacgtta gcttttatat
    10501 ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg catcgaacat tccagcaatg
    10561 aatttgaatt gccgggatgg gaacctgagc gcttagctca tatcaaatcc ttgcttgaag
    10621 cctatgcatc agtagacgaa gaaaaacttc gagaaaattt tgcctatttt ctccaatcaa
    10681 tcatcccaac atgtgaagag gtaggggtca aaatggctgt acatccagat gatccgccat
    10741 actcgatttt tggattacct cgaatcgtaa agaatcgaga agatttagat tggttgtgcc
    10801 gcatagtaga cagcccttat aacggaatca ctctttgtac agggagtatt gcagaagatc
    10861 cagaaaatga tgtatatggg attttagcag aattttgtca aagagatcga atcccatttg
    10921 cacatgttcg aaatattaaa tttttagcta atcgagattt ctatgaggca ccgcataaat
    10981 ccgaatacgg ttcattagac atgtaccgca tactaaaaac aatgtatgac aacggattta
    11041 acgaatacat ccgtcctgat catggaagaa tgatctggaa tgagacagga agaccaggat
    11101 acggcttata tgatcgagca ttaggtgctg tttatctaaa tggattatgg gaagcaatcg
    11161 aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact gtaattttat tatgtaaata
    11221 agaaggatgt tcaaattctt gatacataaa tccggaggtt gttaataagc attcggattt
    11281 atgtatctta tttggtctag gaagtaactt gattttcttt tttcgattga tccatgagtg
    11341 cttcttcttt taattcaaag atatattctg agatcctcat aatcactttt ttccagtctt
    11401 ctggtgtgat gattcctttt aaaatataga tttttttgat atgagaaggc aattgtttca
    11461 aagggcagtc gctgataacg atgttgcagt tctccataaa atcattttgt attttgatcg
    11521 attcatttga aaaaatttgt tctatcttaa cgatcagatc tttactgata taaaaatcac
    11581 gcgtatagtt cacaccaatc acaattcgcg gctgtttttt gtagcgatca tacaaatgta
    11641 ctaggtcttc aaccatccat tgcacatttt ccttttctaa aataactggt aacaagtgtt
    11701 gattttgttc tctgaaatcc atataaaatt gttcaatggc ggtttggact tctttcaaca
    11761 cgctatgttc ttgataaagc atgaaagtag gaaggggcgt atttggttga ttgaagttaa
    11821 gaaatccatt ataaagttta tttcgtgcga atgccaatga gtaaagaatc ttttcttttt
    11881 caggtataaa caaatcaaat acagtacaaa aggactccac catttctctt gaataaagaa
    11941 catgaggaac gtttgctttt tttaaaagtt tgtattgctc caagcttgtt tcttccgatt
    12001 cgattttcgt gatagaaagt cgagctaaaa tattcactaa gatgcgttgt tcgcgacaaa
    12061 ttggcagatt aggtcgcaaa atatctacag agggatcaat aaaaaagtca atatattcat
    12121 actctgtgaa ttctttttgt acgtctttca cagaagttgc aggaaaattc tctttacata
    12181 tttttaatag aaaatataat ttatctatca taccgctatt tagtcggtca agtacttctt
    12241 ttttaaaaaa agtattcatc ataaaagcca ctacttgcgg atcttcatca taaaattctg
    12301 tagcagtact tgaaaagatg ttccaataaa tatctaatgc tgcatattga atttgtacct
    12361 cttttccaga aaaagacttt ctgccattat tagaaaagga gatagacaaa ccgtacaatg
    12421 ctaaaaatgc attaatcttt ttcattttcg tatacaaata agaggcacta tagtttgttt
    12481 gctgacttaa actgataatc gaatttgtct gacagctgaa caaagaagtc aagatctgat
    12541 aactgactga ttcgttgcag tatcttccaa atagacgata atagcagtaa gccggatcaa
    12601 ttccttcaaa attcaacttt aaaaaaggtt tttgcttatc aatatgcagt tctgttagat
    12661 tgagacgctc aaagtcttgt tctaattctt tgatgtatag taaaaaattt gattcagaca
    12721 tatggaaatg atctgctaaa tattgtgtag taataaagaa acgatgttca gataggaaaa
    12781 gaaaaatatc taattttgta ttgctttttt tcttcaagag aaacgtttta atcgcttctt
    12841 gagtttgcat gaaagaggct cctttttact taaattgtta aaacttgaaa atattactgt
    12901 ttttttcata aatttagaca aaaaaacagt aaacatatag gtagaatctc tactatctta
    12961 tttcttgcat acaaaaaaat caaggagtga gagagttatg agatattcaa ccatcttaat
    13021 atcaacattt gcagccttaa gcttatcgct tactataaat cagacagtcc acacagagga
    13081 gatagaaaca gccaaatgga cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca
    13141 ggatgaattt tcatccttca attcaggagt cgcaaaatta agaaaaggac aaacagcgac
    13201 catcaaagca aaaattgact attcaggaga cttagcacct atactacaat cagctgttac
    13261 atttgagaat gttgatcccg ctttgtcgat tggctatgac gagaacactt tgactatcca
    13321 acacaagcaa gcgatattta ccttcaccgt tacattaaat caggacttgt taaaaccagc
    13381 gctttttact gtcaaggtat cagatggact accgaacgat catcatcatt taacgccgta
    13441 tagtcagcgg cagacaattg agcaagattc agctatcgac tcaggaggag atcttgttga
    13501 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
    13561 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
    13621 agagccagac aatgaatcaa aacctgaaat aacccctgga gaaaaaccag atgtagaccc
    13681 agaagaaaaa ccagatgtga ctccagaacc agatacggat tctggaaacc aaacagtacc
    13741 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagcccc
    13801 agaagaaaaa ccagatgtaa ctccagaacc agatacggat tctggaaacc aaacagtacc
    13861 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc
    13921 agaagaaaaa ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc
    13981 agaaaaaata aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa
    14041 tctagcaatt ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag
    14101 cgcccaatca gctgaaacct taaaaagtag caaggataca acctttgctg tcctgaaacg
    14161 aaaaataaac agctaccaaa atccggagag tcacaaaaca aagttatact gtggagcgga
    14221 atcattctat taagtatagc aacaatgctt tctgcaaaaa gatttaaaca aaacagatct
    14281 ctctaacatt tgaataatgt ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa
    14341 atgaccccaa aataccagat tgaaatctga tatttggggt cgttcatact ttatctttct
    14401 tcatatttat tttaagggat atctgtttct tttggaagat ggttcgggat ctttttcact
    14461 ttcaatacat ctaaaaagaa ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca
    14521 aagaaccgtt cgctaacaag taagaccaca aatgtataaa aaatcggcag ttctgttttg
    14581 ctggacatca acttcggatt cagcacataa gactcaatta gatggacaat caaaatcgta
    14641 atcaggatat aaacaacatc tcggatgcct ccttgggaat aagctatgaa agatagagga
    14701 atacaagaaa tgataacacc tgctactggg atcagactta aaatgaaaat catgatcgct
    14761 aaactcagca gctgatgaaa gccaaataca gccaaggcga ttgtagtgag caacgtattt
    14821 aaaagagcga caacaaattg agcttctaat accaaaccaa atgtattgac aaacttatcg
    14881 gcaaaatagt aaatatcttg aaagaaccaa gaaaattcac tttttaaaaa caatcttgag
    14941 aatacaattg tttttttctt ttcaatcata aaaaagaaac ttaagatgaa tgacatagca
    15001 aacgccactg ccatttttcc tatatcctgt aaatagccaa gcgcaatcga agcgccattt
    15061 tgaagctgtt caaaaaaatc gtttcgctca atataagtat ggatatattg taaaacagga
    15121 tctgcatctt ttggctgatg ctcgtaaaaa ttaataacgg actggatcat gtcaaatgtt
    15181 tgatgaataa gcatcgggat atactttgtg aatgccagat agataaggta aacgatcagt
    15241 gtataaatca tgatagctaa aacacctgta gggattcgga caaatcgctg aatgatttga
    15301 acaagatgaa tcatcaaata agtaaagata aatgtgagca aaatggttgt aatcatactt
    15361 ctaactaaga aaagaacaaa aacgacaaat aataaaacag tgagacggcg tattttttca
    15421 ttcgccaaaa aacgctgata aacggtcaaa tcgacaacct ccaaataaca aaaaataaac
    15481 acgttattca ttatatgatg gaatatgaaa ataagaaaga gcaaaaagaa aaaccgctaa
    15541 atgacgttat cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc
    15601 tttttctggt cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc
    15661 aattcttcct gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt
    15721 ttttgcaacg cagcaccttg agcagtcagc gtaacattta cgattctttc atcacccgtt
    15781 tcacgctgac gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta
    15841 ccagaatcca gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat
    15901 aaaactaaca tcacaagata ctgggtatag gtaagattca gcggcttgag gaggggagtg
    15961 tagtgtctaa tgatttcttt agaggcggca tataaaggaa aacatacttg attaactaaa
    16021 tatagatctt ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac
    16081 acaaaaaagt ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt
    16141 ttgaatacgg acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa
    16201 gaccttcgat agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat
    16261 aaagggaaac ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca
    16321 attctaatgc actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg
    16381 ttgcattttc gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat
    16441 tatgcacttc tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca
    16501 taaaattacc acctttaatt atattttata caattgaatt ttacacaata taattgtgga
    16561 aagcaaagaa atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt
    16621 tctcgaatag caaacatata caaaaaatat cagagacaaa aaataatctc atcataaaca
    16681 ttacatatat ttctcaaaaa gttgttttct ttcttcaaaa attacttcac gatggacctg
    16741 atgaagcatc cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc
    16801 catcatttct gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt
    16861 gtcctcgata tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg
    16921 agcagtcaaa ccaagagacg tgttttcatc cagcatatgg aatctcgtac catacaaggt
    16981 aaaaatgact tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc
    17041 aaagattgtt tgatacagtt ctagtgcttt caaactatca tttaatacaa aatcgatttc
    17101 cgttccttta tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt
    17161 attataccag ctaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc
    17221 gattggatga taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa
    17281 ggcacttgga tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac
    17341 aacgatcaat aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt
    17401 aaggccacgt ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact
    17461 catgaccata acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga
    17521 agtgattgca atagataaaa tagcataaag aaactcttct attccaaaaa taaacagatt
    17581 aagagaaaca acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata
    17641 ttttttaaaa atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa
    17701 aatcgcaact cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga
    17761 agtaatcatt gtttctggaa ctattgcaat gattaaagga aaaaccaagc ttccgaaaag
    17821 tactttaaaa aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt
    17881 caacactaaa ataactatag ctcggtcaaa gcctaaagca gcttccagta atattcctag
    17941 accgctgaca cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc
    18001 taatatgaag agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt
    18061 catttattca cttccttaat tcattaataa tactcttatc ttattataac ttacttttca
    18121 ccttaagtta actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc
    18181 ttctagaata tacttctacg ccaaaaactg ttaaaaaact tttactttag aaaattggag
    18241 aaattgatcg cttaagataa attcaggaca ctaaatagta caggaagtag actaaaactt
    18301 ttaaaagttt taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa
    18361 actgttaccg ataacatttt tgaaagcgtt gtcttttgct tctctatcac ttatagtgat
    18421 gacgtcatat taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc
    18481 ggaaagtgaa tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag
    18541 gaaaaatgat atcaaaaaag tatatgtgct atgtggagat ccatatacca taacaactga
    18601 aaaatggtat caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta
    18661 ttgggaaatt gaagtgacga gcgaaacaag tcgcttacag tatgcgttcc atgttgttgg
    18721 ggaagataac acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt
    18781 gattactgaa ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac
    18841 tattccagaa tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa
    18901 cggggacaaa gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg
    18961 agaagacttt ttcgggggag atttgcaagg tgtgatggat catttggatt acttgacgga
    19021 ccttggcatc aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata
    19081 cgatacgatt gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa
    19141 cttgattgat gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca
    19201 tatgggtgtc cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta
    19261 taaagactgg ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc
    19321 agaaactgct gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact
    19381 aaatacagca aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa
    19441 agaattcgat attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg
    19501 gaaaaaattc agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat
    19561 ttggcattcc tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc
    19621 atttacagat tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt
    19681 cagtggaatg aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa
    19741 cttattagat tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt
    19801 gatgaagtct gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg
    19861 gacagaaata gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga
    19921 gaaggaggaa caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa
    19981 acagttgtct aagattattt ctgaaggttc tactcagtgg ctaatagtaa atgatcgtga
    20041 agataagctc tatttcacac ggaaactaga gggacagatc atctatgttt actttaatca
    20101 gtcaaaagaa ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca
    20161 gttgttagaa gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa
    20221 actgttaccg gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa
    20281 gggtgtaaca gcacgttgaa tacaaaggag gaaatgaaga tgaaaaaaag aagtgtgaaa
    20341 cagttgggtt tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat
    20401 ggtaactctt cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat
    20461 tctggatata aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg
    20521 aaaatcaagc tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg
    20581 cctgctggaa agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga
    20641 cagcaaggac atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac
    20701 aaagcccaag tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt
    20761 gttttgtact ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag
    20821 aatctatcca aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt
    20881 ttagctaaat ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat
    20941 gtatttggtg atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta
    21001 gaaggaatct cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac
    21061 ataaaaagtg caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc
    21121 attgacggtc catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc
    21181 aaaattccta ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg
    21241 gtagtcagca attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg
    21301 aatcaggaaa atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa
    21361 gctagggaaa cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat
    21421 gaaacagctc aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa
    21481 aacttgatgt tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca
    21541 gtaaaaacaa tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt
    21601 tttataaaaa atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat
    21661 cttgctcttg ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca
    21721 ttcagatgca gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac
    21781 ttattccagg gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg
    21841 ccatattcgt cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat
    21901 tggttacttt gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca
    21961 ctttgcaatt catcattaca atcattttct tgatttttta cggtttgaat cttttagacg
    22021 cttatcgagt agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag
    22081 tcatacataa tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc
    22141 tcatgatttt tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt
    22201 atgacttcaa tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt
    22261 ttagtatctt ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg
    22321 tgatttggac tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg
    22381 ttgctcacca gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat
    22441 gggcggtccc agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag
    22501 gtgccatcaa tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg
    22561 caatctcttg gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct
    22621 ggttaggatt tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag
    22681 acttatatga agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca
    22741 cgcttcctgc tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt
    22801 tcaataattt ctccatgatc tatctgttta acaatggcgg tcccggaagc gtaggcggag
    22861 gagctggttc tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc
    22921 cgcagtattc tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt
    22981 cattgctggt atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt
    23041 tcattcgagt gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt
    23101 aatactgtca gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc
    23161 aggaaatatt gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac
    23221 tcggctattc agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt
    23281 cctaacaatg atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta
    23341 tcgttttatc ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac
    23401 tatggcagca ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta
    23461 ctggttcttg acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa
    23521 aggatacttt gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg
    23581 gcatttcagg atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca
    23641 agcattatgg gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg
    23701 aacacctgaa aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa
    23761 ccaaagagtc tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt
    23821 attcttcttt ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata
    23881 ggagcagagt atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac
    23941 tcaagtgttt gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt
    24001 tttagtttcc ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat
    24061 tccattagaa caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt
    24121 ttctgaactt gaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac
    24181 ccctgaaatt ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt
    24241 tattgatttt gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg
    24301 ctatacgatg aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt
    24361 ccaacgattt ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta
    24421 tagtttaagt cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc
    24481 ctttttcttg tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag
    24541 tgcaaatttg atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt
    24601 tatccacttt gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct
    24661 tttatgggtt tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc
    24721 gatttatgcg acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct
    24781 gaaaaaatta aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt
    24841 ttttttaagg aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc
    24901 tttctcgctc cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac
    24961 ggacactcct ccccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac
    25021 aagtaacgct tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg
    25081 aagtatccaa gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa
    25141 agattatcta aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga
    25201 tatccatgcg cattatgact taggtaacga cttttataaa ctttggctag atccaacttt
    25261 gacttattct tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa
    25321 taaagtccat catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat
    25381 cggttgtggc tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac
    25441 tgggatcaca ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca
    25501 tttagaagat aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt
    25561 tgatcatatc acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta
    25621 tttcaaagtg gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag
    25681 ccgacaacaa ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta
    25741 tgtccctggt gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga
    25801 tttggaaagc ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca
    25861 tcaagtccaa gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct
    25921 atatttacaa gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt
    25981 gcttgttcaa cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta
    26041 ctgtttaaag actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt
    26101 tgtctaactt ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata
    26161 aaagtttggt tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa
    26221 tagaatacta ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta
    26281 gtttatttgc agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg
    26341 ggaatacgtc ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag
    26401 caagcacatc ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata
    26461 tcaaagtgtc tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa
    26521 ttactagttt ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg
    26581 atgatcaaaa agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga
    26641 atccagaaac tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg
    26701 atgttgataa attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa
    26761 gcggtacggc aacagattgg gatttggata aagatttagg tactacttat tgggaagtca
    26821 aagtaaaaga cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac
    26881 tgtcaactga acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta
    26941 gtcatgatac actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac
    27001 gacctttgcc aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat
    27061 gactacccag gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag
    27121 ctgtacgatc aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg
    27181 gagtatcaat tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct
    27241 tgcgtatgaa aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat
    27301 gagtgtccag gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat
    27361 cactgaatta aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt
    27421 tgaggccact tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat
    27481 caaattgcct ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca
    27541 gtttccattg acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac
    27601 agaacaagaa gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta
    27661 tatcaagccg actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat
    27721 ccaaatcatt ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg
    27781 tggcgcaagc atgttacaga ttggtaccga gcttcataaa gaagggccgg aaattttttc
    27841 tagaatcata aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga
    27901 atttaaaggc aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc
    27961 gtcttttttt ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt
    28021 tagacgaact tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca
    28081 gaattagcaa aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata
    28141 cagaaaaaaa taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc
    28201 gagagtaatt cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc
    28261 ccatttcctt taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct
    28321 cgtttatttg aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg
    28381 ataggtctag ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca
    28441 gacccagtca tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga
    28501 tcaagtggag gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt
    28561 gatggcggtg gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct
    28621 tcgcgaggga cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt
    28681 gatttcggct tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt
    28741 atccattccg gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa
    28801 aaacggttga agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag
    28861 gcagtacttg ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca
    28921 gagattcctt acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc
    28981 gcagaaacag cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa
    29041 gaagaacttg aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct
    29101 acttacatcg attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat
    29161 caagaatacg atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa
    29221 gatttgcaaa gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta
    29281 gaaggtttag acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca
    29341 cagttggcta atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa
    29401 aacatgcctc taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa
    29461 atcggctatc tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag
    29521 aaacaaggag aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt
    29581 ttattttaag cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg
    29641 tagaaaaaaa gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt
    29701 ataatgatca aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac
    29761 ggttaaatgt caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt
    29821 caaaaagaga atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa
    29881 aattctccct ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag
    29941 atgattcagg aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca
    30001 atactagcta tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg
    30061 ccacgaatga tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg
    30121 attattatct gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg
    30181 agaacgttta tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc
    30241 tgaaaaagaa aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa
    30301 tatctgaaaa atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt
    30361 cggtgagtga gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc
    30421 tttcgtactg caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg
    30481 aaatctggta gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt
    30541 atttattcgt ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct
    30601 gttatatttt gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac
    30661 gattaccagc agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc
    30721 aggtcagtgg gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat
    30781 cgttttgccg caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct
    30841 agtgaaaggt acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa
    30901 gatcataggc ggtcggacat tcgattattt ttctctctat attttagttg cactgattta
    30961 ttgggtcatt tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca
    31021 tcagtcaatc tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt
    31081 ttcttgtata ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata
    31141 tgttcggagg tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac
    31201 caatattgca tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa
    31261 ggaattgtag atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc
    31321 tatgagctga aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga
    31381 cattataatt attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct
    31441 acaggaatag gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct
    31501 ggtacatttc tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct
    31561 ttgacaaacc gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag
    31621 cgaggcgtaa aatattttcc aacagatcaa ttgtacaaag aattgaaaag acgttcagaa
    31681 aatcaagatc cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt
    31741 caggcaatca atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg
    31801 aggcaacaac agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact
    31861 atccttattt aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag
    31921 gattgctctc caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta
    31981 aaaatgtgat cgaattattt caaaaaaagc accatccaat cgctgtgatc caaaatcccc
    32041 aagtaggaca attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata
    32101 gctctgtcgt ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac
    32161 ctccagcgtt tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac
    32221 agttggcagg agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc
    32281 tgcccgaaaa caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt
    32341 atgcagataa aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat
    32401 atattggatt ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta
    32461 gccgagcgct tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac
    32521 attttgtctc tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag
    32581 gagataaaat gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa
    32641 tgattgaatt attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa
    32701 agtggtcact tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt
    32761 ggcttaaata ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg
    32821 taaatgaaaa aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa
    32881 gaagtagaag aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc
    32941 tctcctcaat ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa
    33001 agaaaagaaa gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc
    33061 tcaagcgtgg atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct
    33121 tatttatcga ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa
    33181 ccgttcttag aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc
    33241 gatacttatc cagctaatga accgatggaa aagaccatct attctgctgg attcacttat
    33301 caagggatga ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc
    33361 aattgactat aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat
    33421 catatgatag ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt
    33481 ccgaaaatgc ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc
    33541 tgaaactccc ttcatcgaga ggtcgtgaca tagcttttgt cacgacctct cggcttatcc
    33601 tacgagtatt attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc
    33661 ttggaacgct ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa
    33721 ctgtgctaaa tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc
    33781 acgttttttc aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac
    33841 taccgtcccg aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca
    33901 atttcctact gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc
    33961 atattggtcc cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga
    34021 aacaaaataa taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt
    34081 aatgatcttt tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga
    34141 aggaccgata aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt
    34201 gaaaaagctt tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatatt
    34261 ataccagcaa gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa
    34321 ttttcaatcc gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac
    34381 cagaaatgat cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg
    34441 ctgttgtacg ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt
    34501 catttgtaac cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga
    34561 ttccgctgat gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc
    34621 cgaatatccc gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca
    34681 tagcagcaac cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga
    34741 aaaatgtctg ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat
    34801 agggatttac aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga
    34861 tcacatattt agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag
    34921 acatagccga tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt
    34981 ttatggaaat aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt
    35041 ccaatttgcc catcccgttg attttactta atcctagacc aacagctttc ataaataatg
    35101 gaagaatctt gatatagcgt agaataccga taatagcaga aataaataca attggcatca
    35161 atacggaaag aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa
    35221 caccttgccc agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg
    35281 ctgtaccaaa agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca
    35341 caattagtgg tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta
    35401 atgtgacaaa taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa
    35461 ttccgtttta ttttacctgt tttgcaaata aaatactaat ctttagtgaa attttcatta
    35521 cttttttaga gtgaaacgca ttcattttcc attagaaaat aaagcgaaca aaataaaagg
    35581 tttaaaaagt gtaacgtctt agtaaagtct ataaaaaaac gaaactatcg attaagctaa
    35641 tagtttcgtt ttcaacattt ataagtaaac tttttctatt ggtaatatag attttcggaa
    35701 gggtagacag gtgcgcaggt aatatcgatt cctagttttt tcaatgtttg ttcatcattt
    35761 ttattgacca tcacagtaga gtgggcttgt gctccctcaa gttcagctag tttatcataa
    35821 gcaacttgag cgattggatt cgttactgca ctgattgata aagcgatcaa gacttcattg
    35881 atgcttagtg catccaaaga ggaatgaagt gtctttgatt tcaatccttg tattgtttca
    35941 agaactaatg gtgacaataa aggaatgtca tctgcgatat gggctaaatg ttttactgca
    36001 tttaagataa ctgccgctga cgcatccatc aatgaacttg tacgcccggt aatgatgact
    36061 tcatctggta attcgattgc aatcacagca gaaggatctt ttgtaggact ttgcgcttga
    36121 atcttatctg catagtcatg ggcagggact accacgtttc ggtcttcagg acgtaaaccg
    36181 acttcttcca taatcagttt gattcgatta actgcttctt cgtcgatcaa tccttttttg
    36241 aagtcgcatt ctgtttggaa ataacgacgg atgatttctt gtttagaggc ttcttggaca
    36301 acggtatcat ccacgatccc aaatcctaca cgattcacac ccatgtcagt aggagattga
    36361 taaacagatt ctttaccagt aattttttca ataatacgtt tgattacagg aaatgtctca
    36421 acatcccgat tatagttcac agctacttta ttgtaggcat caaagtggaa ggaatcgatc
    36481 atattgacat cttttagatc gactgtggct gcttcataag caatgttcag cggatgtttc
    36541 aacggaacat tccatactgg gaaagtttcg aacttggagt aaccagctgc atgtcctttt
    36601 tggctttcat gatacagttg gttcaaggaa gtagcgagct ttccacttcc tgggccagga
    36661 gctgtcacta caacgattgg tttagttgtt tcaatatact cattttttcc aaaaccatct
    36721 tctgagacga ttttttctac gttgactgga tagtcttcga tttctgagtg tttatagacc
    36781 ttgatgtttc gtctttctag tttattgata aagactttcg tggcaggctg tccactatag
    36841 cgagtgataa cgacactgtt gattaataag ccataaccac gtaattcatc gattaaccgc
    36901 aagatatcca tatcataagt aatcccataa tcaccacgga tcttattacg ttcaatatct
    36961 ccagcataga cgcaaatcag tatttcagct tgatctttca atttttgcag caatttgatt
    37021 ttcgcatctt cttcaaatcc tggaagtaca cgtttcgcat gcttgtcgtc aactagcttc
    37081 ccaccaaatt ctaaatataa tttgtcatag tggttcactc gttccaaaat atacgctgac
    37141 tgctcttcaa tatatttttc tgaatcaaaa ccaatttttt tcactaggtt ccctccttaa
    37201 gtactaaagc attttttcat ttttttgagg attcgtcaac tggaagagcg aaattcctca
    37261 aaaaaacaaa gaaaatggtt taaaccaact tgtctagata gttattcatt ggtatgatag
    37321 tttttgataa ggaaggtgct acatgaaaaa aagacagaaa aagaaaaacg catataaaca
    37381 ctatatccgt tcgattttta ccggttatga aagaatgctt gaagatcccg aattggaaca
    37441 attgacgttt acttatctaa acgaagaaac gcagctaact cgtgatgagc atcagcgcat
    37501 tcatttcaca acaagagatc tgcctagtaa ataaaaaata agataaaggt catcggattc
    37561 gattctgtcc tatcagatgg aaagactagt tgatcgaaaa aaaggctgta ccaaattttg
    37621 gtgcagcctg ttttatggag cattgcccgc tcttttttat aacaattttt tacagaaaat
    37681 ggtactattg aagtattaat aagtgaaaaa cagatgagta agaggaggca agtagtatga
    37741 aagagccaga tacaaatgca aattatgagc cagacgaact agaggagacg aatgcggatc
    37801 aggatacagg acaagaatcg tcttcttttt acgatatcaa agaaaaagca agcatgaatc
    37861 tttcccaatt attagaagac ttacaggctt ttgaaaaagc tgtccgcgaa gaagatatcc
    37921 ctgagatcta ccgtttatac aatggccgat tgaatgaaga attaaaaaga agctcaaatg
    37981 aaaatcacga gatcgatcaa ttgctgatgc gtaagatcca tgatcgtttt ttacaggaat
    38041 ttccttttat ggaacaagta gaaaacatct cgccaacgat gagctattac aaaatcggca
    38101 cttattacca tgatcggccc acggtcggta ttgatgcaag tctgccagaa atttttgttt
    38161 tgcctaagat cgatgaagag tgggagaaat attcccaacc ggagtcaacg gactatgaca
    38221 aaaaaatcaa tgagctagac gcaaaggtga tcactgctca gacagaaatt gaacgtttag
    38281 atgaacaaat aaaagaaatc aatcgacaaa tgactgattt gaacgacaat aaaggattct
    38341 tgaatcgtaa aaaaatcgag gaagaaattc aagaattaga gaagaagaag caagtactat
    38401 ctaatgaaaa attaggctgg cttccttata ttgagacgcc tgaaacaatc cagcagcaaa
    38461 aagaagcatt gaagcaagaa gcaagagcag accagcttcg tgcagccatc gtagaaaaag
    38521 aacaaaggca aatcagacgc tatttcggta gcaaagaggg attcggtcaa gcaatccatg
    38581 aattcttgat gaattatctt ggcaatgaga atcctaataa tcaatctaat gaaggaggtt
    38641 ccgagtatga atgaacacga tgaagcagaa tggacaaaaa atgaagaaca aacagaagat
    38701 catgaagaaa cgaacacttc attggaagaa caaacaagta atcctctgga tgacacagaa
    38761 gaaatcccta tgctagagga aacaaaaata cacgaaaaag aaaaagtaac tccgacgaat
    38821 acgaatactg cagaaaacac ccatgcttac gaaataactg aaaatcccgg gtatttagaa
    38881 ggaaaagagc aagatcatca agatatcgtc agtttgattg aaacagcgga agcagaatta
    38941 gcggatttac gtatgagaaa agatttgatc gaatcagatt ttccacaatt attagaatca
    39001 tatgatcgtt ttatattgaa tgaagaacca atctccacga tcggaaagac aagcctgatc
    39061 gaatacttca cgtatgaatt actgaaaccg ttgaatgata ttggtctgga acggtcaaat
    39121 tcagcttatg acacatggaa aacaagacat ttttcgatca attatacgtt gaatggacaa
    39181 aacgaattag tcttttcctt tgtattaccg accatcgatc aacgatacca agtggaatcg
    39241 atgagtctcc taaacgtatc accagagaca atggaaatca atgtccaaga tgaccgggtg
    39301 ctttctttga tccgacactg gtcagtggat cgagtattct ctgcagggca gatcacgata
    39361 ttcaatcaca aattgaatca attattagcc catgcaagaa cacttggttt taccgttaat
    39421 cagacattac tagacaatac gaagccactt cgtttgaatc ttcagagcga atttgaattg
    39481 acgaatgaag tattggatga tatttttatc gtggcaatga aaaatccatc ctacgatatg
    39541 gaaaagatca acgaaactac ttatcaagta cgattagata aaggacagtc tttaacgata
    39601 acaacaaacg aaaaagatca aacagtcttg tcgatctcat ctggagacta cccacgatct
    39661 gtcattgatt tctttatcaa ttacgaattc ttggtcccat taatggtgag aaagtcctga
    39721 ttggataagt tggattacca gatgtcattc agataattct gttccaaagg acttgcggca
    39781 gttatccaga ataattgtca caagtctttt ctgtatgtac taaatggacg tgaataactt
    39841 gctgatgaag gagggatttc attaggaatg tccacaaata aaatagcaca gcttagctta
    39901 ttgtctgctg cttgtgtagc aggtaggatc gcttttcaat ttattccgaa tttccagcca
    39961 atgactgcta tttttttatt tatagtactt tacttaagct taaaagatgc gttaattgtc
    40021 atgagtcttt ctattgcgat cagcagtttt tattttggtg ttggaccatg ggtcatcggc
    40081 caatggatca gctatactgt tgttctgagt ttgttttcaa tcgtctgctt gagaaaaaca
    40141 gtgcaaagga atctatggtt aaagggagtc tgtttttttc tggcgggcat ggtttacgga
    40201 ataggtatga ccgtttttga tacgctgtta tatcgtttgc ctcaaccttg gatctattac
    40261 cttcaagggg tgtcgtttga tttgatgcac agtataggca atgttgtgtt ctttcttgtt
    40321 tttctgccag tcgtcaaacg tttttacaat cattcaggag gaaaaaatga aaaaaataat
    40381 ttatagtttg cttgcaatga gtgtcagtat actcattttg acaagttgca gtacaaccta
    40441 tacacaatcg gcttccaacc aaaaggagga agtaaaaaca tcgcaaaaag caacaatcac
    40501 gttacaagaa aatggtcaaa acttttcgga aaaagaagtg gtcttcaaaa aaggcgatga
    40561 tttactgagt attttgaaac gaaattttga agtcaaagaa gataacggct tcatcacttc
    40621 gcttgaaggg cactcacagg atgagaaaaa tcaactctat tggatgttta ctgtggacgg
    40681 gaaaagtgct actactggtg ccaaagagat caaattgaat gatggacaat cggtcatttt
    40741 caatttgtct aaactataag tttcataaaa aactgttaaa gggcgaatat tgccataatt
    40801 cagtgagttc agttgatgaa agaaggaaaa taacatggaa aattttaaaa aaagcggaat
    40861 gttttccgta attgctgctc taggggctaa tattctagtt gctatcagca aatttgtcgg
    40921 ctatgcaatc agtggcagtg ccgccatgct aaacgaaagc atccacagta tcgttgattg
    40981 cagcaatcag attttgctgt tattcggtga taaacaagcc aataaaggac agagcgagtt
    41041 gcatcaattt ggtgaaggac gagcaaaata ctttttcagt acaatcgtcg caatgatgct
    41101 tttcttcggc ggtggggcac ttggggtgat ggaagctttt gaaaagttga cgcatccatc
    41161 ccatgaagtg ggtaatccga tcattgttat agcaatactg ttatttggtt tggtaatcga
    41221 aggaagttcg ttacgcgtgg caatgaaaga aatcaaagaa ttgaatactg aaaaactttc
    41281 cacgatgcgc tttttgcgcg aaagtcgaca cagtgaaata ctgattattt ttacggaaga
    41341 cttgtgtgct gtaatcggtt tggtcttggc tttagcagga acaatattga cttatgcaac
    41401 cgggattgct gcatttgatg cgatcagcgg attgctgatc ggtttcttgc tgatgggagc
    41461 cgccattttc ctagcaaaag aattttatag tctgatcatc ggtgaaagcg tgacagcaag
    41521 cgatttatca aaaatcaagt tagcttttga acgtcctgag atcagtcggc tgatcgatat
    41581 aaaaacagtt catttaagtc caacggagat tttagttgca gcaaaagcag atatcgttgg
    41641 taacaaagag aatgaagctt actcggtcat caatgatatt gaaaaaaata tgcgtcagtc
    41701 tcttcctgac aagaagatgt atatatacat tgaaacagat aaatatgacc caaattattc
    41761 tcgtaaataa aacgtttatt catgaattga agcaaaaatg agaaaaatat aatcttgttt
    41821 ttaaataaaa cggctacaat ttagcgaatt tatgttacaa tgagtccgct gtttatttgt
    41881 tgtaattaaa ggagatattt taatgaacaa aaagaaaagt gcgccatggc ttcaagcttt
    41941 gcatgcagtg atgccacttt gtataagcta tataccagta ggattagctt gcggagtatt
    42001 gttgcaaaaa gttggatttg atcctctctt atcaggactg ttatcgattc tggtcttttc
    42061 cggtggcgcg cagtttttag ttgcatctat gcttacgacg caagcatcat ttgcaacgac
    42121 attattgatg gttttctttt tagaattacg ctatacatta ttaggagcaa gtcttgccgg
    42181 ttttatgaaa aaagaaaagc ggacgttttt ggctgtcttt tctcaatcac tgaatgatga
    42241 aaactatgcg gtgaactact taaagttttc aactgaccct tcctggaata aaagaaaggc
    42301 tttatatgtc aattggttct caatgactgc atgggccggt agcaatatga tcggtaattt
    42361 tttcggctcg gtgattcgag tagatgctga ccttgtccat tttgctttga cggccatgtt
    42421 cattttcatg tttatcatgc agatgaaaag cgcactactg atctttacag gtttattctc
    42481 aggcgtatta ggggtcgtat tcatggtatt attccaaaat actttcggat tgattgcagc
    42541 aacagtcatt gcttcatttg ccggatttat gctggagaag gcattcaaaa aagaaaaagc
    42601 taagaaacta agagaccgcg gtaaagatgt caatgagccg ctcttcaact tcccggaaca
    42661 ggaggccaat caccatgact aaactatatt tgctactttt agttgcttgt ctgttcatcg
    42721 tggcatatat cccgcgcttg ttcccgatgc tttattttac tcatcgaaaa gtgccatcct
    42781 ggttcagtga ctggatgaaa tatgtaccgg tggcattatt tgcggcgtta gcttttaaag
    42841 atgttttcat tactcatgaa catctggata ttgcttggaa tatcaaaata gctgcaatga
    42901 ttctagtagc aggcgtggct tacaaaacac gttcgatggc gttgtcagtt ttgacaggac
    42961 ttgcgtctgt ctttttgctg tctatgcttt aaactgtttt attttattaa aaacagagat
    43021 tgcgacataa gttgttcaaa ctgatctatc cgaactgcat ttgcaacagt caattctgga
    43081 tgcaagttta ttcgtaggga taaaaaagat tagtgttggc ttatgatgca agctcttttt
    43141 tattttagga attagagagg gatttgtcct tctatgattt tttgctataa tagggaagat
    43201 gtttatttta tgaaagaata gttgagggaa tttaaatgaa taaaaaattg atgcaaggaa
    43261 cattttggct aacctttgct aatcttctat gtaaagtttt aggggtagtc tatttgattc
    43321 cctggctaag tatgatgggg aacaatcaag atggtatgct tgctacgaca ttgtataatg
    43381 ttggctatct tccttatgga ttgttcctga tgcttggtac agtcggattt ccaaatgcga
    43441 ttgcaaaaaa agtagctgta gccacaaaag aaggagataa cgctgcttgt cggctgattt
    43501 ttagaagtac gatcaatatc atgtttgtca tcggtatcgc ctctgctgca ctgatgtatt
    43561 tatttgctcc tttactagcc ggaatcagtc cgattgctaa cgttaataat gggatactag
    43621 ctatcagaag tttatgccca tctttgattg ctatcccaat tcttagtgca atgagaggat
    43681 atttccaagg aaaaaatgat ctgcggcctt atggaacttc tttgattatc gaacaggctg
    43741 tgcgagtgat cgttatcttg gctggtactt attacttgcg cgtattgact gacggaacca
    43801 tattagaagc tgtattgatc agtacagtcg cttctttctt cggtgggtta gctgcgatta
    43861 tccatatgta tatcgtcgga cgcagaaaag acttcttcga acttaaagat tttttgattt
    43921 ccagccgtta tttcgaaaga gaaaaccgat ctgcctctgt ctctatcatt cgggaaacac
    43981 taccgtttat ttttgtcggc tcagtcatta ctatcgttca aatgatcgac caagtaacga
    44041 tgaaaccact gcttcacttt ttccgtccag agatcgcaga tcagcaactg gaattcttat
    44101 tcagccgtgc ttctgtcaat ccaaataaat tgacattgat cctgatctcc atggtaggaa
    44161 cagtagctat aagcagcttg ccaatattaa gcacgatgaa gaaaaaagat cggatacaaa
    44221 tcgaaaaaac agtaggagat agtttttcga ttgcgttatt gattcttctt ccttcattga
    44281 ctggaatgtc tttattagct ggaccactat acacattgtt ttttggctat gatcctgaaa
    44341 gtgtcggata tttccaaatg gctttgctag cttctttgtt tttctcttta ttcacgatcc
    44401 tatctacgat gcttcaatct ttgaatcacc atcgttttgc gatccgatta actgtagaag
    44461 caattatcct gaaagtcatc ttccaagtaa tcggattagg attagttggc ggatacggga
    44521 tgagcttatc aaatggctta gcattcggta ttgtctttgt tcgcggctat cactttatgt
    44581 gcaaagaata ccgaatagca cctttagcaa agatcagcaa ttttttctta aaaactttcc
    44641 gctccaccct gattatgctt gcagtatgtt ttgccgtttt ctttttgctg aatcagcgat
    44701 tgtcaatgga atcaaaaagc tatgcaatga tttattgtgt ggctgtagga agtattggcg
    44761 gcttagtatt tttattttct caattcggaa aaaatgggtt tcgaatgttg aaaaatgtta
    44821 aacatcatag cagaagcaaa gaataggtta actaatcgtt ttttgctgtc acttgaaaaa
    44881 cggcaactcg tatgattacg cttgtcgttt ttctattttc caattttagt ttcatatcta
    44941 atcttactta tgatatagtt ataaggtctg gaaaaattct ttgaaacgag gaaattaaac
    45001 acatgaaact tgcagtagtt acagatagtt cggcatatct gccggaacgt atcaagaacc
    45061 atcccgactt attcgttatt ccaatccctt tgattatgga tgggaaaatt tataacgaag
    45121 gaatcgatat cgaagcggat gaatattatg gacttttaaa aaacagtaaa gattttccta
    45181 ctacttcaca acctgtcgta ggggaagttt tgggtttata tgaggaattg aaagagaaag
    45241 ggtatgacac gattttaagt atccatcttt cttcagggat ttctggcttt gtcaacacat
    45301 tatttgcgat gaaagatgac atcagcggag taacggtcat tccttatgac tctaagatca
    45361 ctagtatgcc gatgggacac atggtagaag ctgccttaga cttaaatgat gaaggtcagt
    45421 cccttgatga aatacttgca catatcgatc gaatccgaga taatacctat gcttatctga
    45481 ttgtagatga tttgaacaat ttagtacgag gaggacgttt gacaaatggt gcagcgctga
    45541 ttggcagctt attaaaaatc aaaccgatcc tgacattttc tgaagggaaa attgttttat
    45601 tcgaaaaaat ccgttcaagt aaaaaagcat ttgctcgagc tgaagaaatt attggtagaa
    45661 gaaataacga aatacaaccg ccagtcaaac tttacgtgat acatgcaaat aatttagaag
    45721 tagcgattgc ggagaaagag aaattgcaga aaaaatatcc aaatgcagaa atcgaaattg
    45781 gtcatttcgg accagtcatt ggtacacatt taggtgaaaa agccatcggc attgccattt
    45841 cagcgcaata attcctttta ttcaaaaaac ataccaaaaa tat
//
LOCUS       DASHXG010000020        42959 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.020, whole genome shotgun sequence.
ACCESSION   DASHXG010000020 DASHXG010000000
VERSION     DASHXG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.020"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(151..2304)
                     /locus_tag="U2R59_001233"
     CDS             complement(151..2304)
                     /locus_tag="U2R59_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEM8965639.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="U2R59_001234"
     CDS             complement(2598..3446)
                     /locus_tag="U2R59_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8965640.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="U2R59_001235"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="U2R59_001235"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEM8965641.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDSDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="U2R59_001236"
     CDS             complement(5947..6126)
                     /locus_tag="U2R59_001236"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEM8965642.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="U2R59_001237"
     CDS             complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="U2R59_001237"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEM8965643.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPAELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /locus_tag="U2R59_001238"
     CDS             8274..10553
                     /locus_tag="U2R59_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8965644.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="U2R59_001239"
     CDS             complement(10646..11293)
                     /locus_tag="U2R59_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965645.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="U2R59_001240"
     CDS             complement(11472..12191)
                     /locus_tag="U2R59_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965646.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="U2R59_001241"
     CDS             complement(12322..13473)
                     /locus_tag="U2R59_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEM8965647.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="U2R59_001242"
     CDS             complement(13690..14430)
                     /locus_tag="U2R59_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8965648.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="U2R59_001243"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="U2R59_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEM8965649.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="U2R59_001244"
     CDS             complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="U2R59_001244"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEM8965650.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16041)
                     /locus_tag="U2R59_001245"
     CDS             complement(15391..16041)
                     /locus_tag="U2R59_001245"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEM8965651.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="U2R59_001246"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="U2R59_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEM8965652.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="U2R59_001247"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="U2R59_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEM8965653.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="U2R59_001248"
     CDS             complement(17484..18011)
                     /locus_tag="U2R59_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEM8965654.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="U2R59_001249"
     CDS             complement(18191..18976)
                     /locus_tag="U2R59_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEM8965655.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18969..19838)
                     /locus_tag="U2R59_001250"
     CDS             complement(18969..19838)
                     /locus_tag="U2R59_001250"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEM8965656.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="U2R59_001251"
     CDS             complement(19839..21218)
                     /locus_tag="U2R59_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEM8965657.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="U2R59_001252"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="U2R59_001252"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEM8965658.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="U2R59_001253"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="U2R59_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEM8965659.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="U2R59_001254"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="U2R59_001254"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEM8965660.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="U2R59_001255"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="U2R59_001255"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEM8965661.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="U2R59_001256"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="U2R59_001256"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEM8965662.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="U2R59_001257"
     CDS             complement(25176..25400)
                     /locus_tag="U2R59_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEM8965663.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="U2R59_001258"
     CDS             complement(25453..26415)
                     /locus_tag="U2R59_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEM8965664.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="U2R59_001259"
     CDS             complement(26425..26865)
                     /locus_tag="U2R59_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8965665.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27171..28136
                     /locus_tag="U2R59_001260"
     CDS             27171..28136
                     /locus_tag="U2R59_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEM8965666.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28193..28423)
                     /locus_tag="U2R59_001261"
     CDS             complement(28193..28423)
                     /locus_tag="U2R59_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEM8965667.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28509..29395)
                     /locus_tag="U2R59_001262"
                     /pseudo
     CDS             complement(28509..29395)
                     /locus_tag="U2R59_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(29484..30707)
                     /locus_tag="U2R59_001263"
     CDS             complement(29484..30707)
                     /locus_tag="U2R59_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8965668.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30724..31770)
                     /locus_tag="U2R59_001264"
     CDS             complement(30724..31770)
                     /locus_tag="U2R59_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8965669.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="U2R59_001265"
     CDS             complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="U2R59_001265"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEM8965670.1"
                     /translation="MVEMLKGIAASDGIAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33661..33927)
                     /locus_tag="U2R59_001266"
     CDS             complement(33661..33927)
                     /locus_tag="U2R59_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEM8965671.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34406..36640
                     /locus_tag="U2R59_001267"
     CDS             34406..36640
                     /locus_tag="U2R59_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8965672.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36788..37108
                     /locus_tag="U2R59_001268"
     CDS             36788..37108
                     /locus_tag="U2R59_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEM8965673.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37313..37537)
                     /locus_tag="U2R59_001269"
     CDS             complement(37313..37537)
                     /locus_tag="U2R59_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HEM8965674.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37735..39315)
                     /locus_tag="U2R59_001270"
     CDS             complement(37735..39315)
                     /locus_tag="U2R59_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEM8965675.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39716..41092)
                     /locus_tag="U2R59_001271"
     CDS             complement(39716..41092)
                     /locus_tag="U2R59_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEM8965676.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41220..42338)
                     /locus_tag="U2R59_001272"
     CDS             complement(41220..42338)
                     /locus_tag="U2R59_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8965677.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42480..42914
                     /locus_tag="U2R59_001273"
     CDS             42480..42914
                     /locus_tag="U2R59_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8965678.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
BASE COUNT        12191 a         9213 c         7434 g        14121 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgaatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcggc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctcatttaaa
    27001 acaactgata aatcagcatt tataatttct tttattagaa aaatcatcta tctcacatat
    27061 tttgattatc aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt
    27121 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
    27181 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
    27241 aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc
    27301 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
    27361 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
    27421 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
    27481 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
    27541 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
    27601 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
    27661 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
    27721 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
    27781 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
    27841 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
    27901 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
    27961 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
    28021 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
    28081 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
    28141 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
    28201 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
    28261 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
    28321 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
    28381 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
    28441 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
    28501 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
    28561 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
    28621 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
    28681 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
    28741 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
    28801 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
    28861 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
    28921 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
    28981 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
    29041 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
    29101 ctggtgtact tgtagtcaaa tcaactaaaa tatgtcctga gatatctgca gaaaaaatcc
    29161 ccgactgtcc atagtagatt tcttctacat ctttggggta acctaccatt gtaaagagaa
    29221 tattactttg ttctgctacc gcttttggtg tatctgccca gatagctcct tctgttacta
    29281 aaggatcagc ttttgctttt gtccgattat agacagctac ttcgtgtcct gcttctagta
    29341 gatggcgtgc gacagcactt cccatgacgc ctgttccgat aaaaccaagt ttcatttttt
    29401 cgacctccta aaaatcaaaa atccttgctt ctatgctagt atacgctaga aacaaggatt
    29461 ttttcataaa aaatgtttga attttatctt ttaaatgaat ttaattttat tttgattcgt
    29521 tcaatcgagt cttcttcttc ttttcttcgc atctcttctt catgataaac aaccatgtct
    29581 tgataaaatt cgatcatagc ttcgccgaaa tgtgtagatg aaatatcata aagtttagct
    29641 tctaaaactt ttggatcttt aggaacttca ctggaaatat aatcaataag tgctggtgca
    29701 aagtcttcgt cggtttcaaa agttttccct aatgaaggat gatcgaacaa tcggttcaaa
    29761 taagcatttc cttccacgac acaaggtgtt ccggctgcca tcgcttctgt ataagtaagc
    29821 ccttgtgttt ctgaagtaga agcactgaca aaataatctg ccgctttata ataaagtgct
    29881 acatcattgt tgtccacttc tcctgtgaac tgcacaaatt cttctaactg cagttctgag
    29941 atcaattcct ctaactcttc tacataaggt ccttttccta cgataactaa tctggcgtta
    30001 ggataagcgg agatgacctg aggaaaccca ttaatcaagg cttggatatt tttctcataa
    30061 gaaatcctgc ttaaagaaag aatcatcaaa tggttttcct gaagacctag tgactccctt
    30121 aatttgctga tatcctgctg agtgatatca gaacgtttga atttttcaat gtcgatacca
    30181 gtaggaatca cgcgaagcgg tgctattaca ccatagctgc gtaatgtatc aataacacgt
    30241 tcacttggac aaactacacc tgtcgtatga tttgcaaata atctagacaa gtattttaca
    30301 tgggattgcc tgatcacttt tcctttaccg atataatgaa ggtagtcttc atacatcgta
    30361 tggtaagtat ggatcagagg tattttcaac ttcttagcta ccatcttccc aagtatccct
    30421 gctccgaatt ctgtatgggt atgaataaga tctagttcta gttctttggc aaccaaataa
    30481 gcataccaca tgcctctaac aacaactctt cgatccttga aagaaataaa tggtacactt
    30541 ggcattcgaa tcacatcttt ttccaactta tccgcattag gatcggtcgt tgtaaaaata
    30601 tagacttcat gcccatgtct ttctaattct tgttttaatg ttttgatcga tgtagcaact
    30661 ccgctgactt gcggaaagta ggtatcggta aaaaagccga ttttcatgtt tttcgcctcc
    30721 aaactagtcc ttgacctgat ttactttttt taatttgcta gagacttttt cattcagtac
    30781 actttcgtat acatttttaa gttcttcacc gattttattg atacttcgct cttttgctgt
    30841 ttgataaccg gcttgtgtcg tactcggtag ttcttgattg gtaatctgtt ggatcagtcg
    30901 gataaattct tcgtttgtct tccccatata gcagttcttg ctatcttcta accagccatt
    30961 atacactgga atatctcgaa caagtacgtt ttgtttgctt gctaaagctt ctaaaacaac
    31021 gatcccttct gtctcttcat aagaagggaa aaagaataga tctgcacctg aatacgcacc
    31081 ttctatgatc tctccacgaa tgtaaccagg aaacaggaca ttttcaggat gatcttcttt
    31141 tacaattttc cggatgttcc gaggaatcga gtacatggga acatgaccaa accaaataaa
    31201 tgtgtattcg ggcatcttct tagcaatttc tacgaaatca atgattcctt tacgttcgaa
    31261 aaacaaaccg acacaaatga ttactttttg atccggagac agtttgaaat attctctgaa
    31321 cttttgttct ttcattggat cagggtgata tttctctaag tcgatcccat tggaaatagc
    31381 ttgaatcggc acacggatac catagctttc caacaactgt tttgaataag gtgttggcgt
    31441 gatcagatag tccgcttttt ggtacaatcc taccagatat ttttttacga taggagaaag
    31501 ctggttcgat ctgataaagg aatttcggaa atcttcctct gtagaatgcg catgatagac
    31561 aacttttttt ccttctcttc tggctttatt gaccatatta tgactattga ttccgtatgt
    31621 attgatgtgc aggatgtcat aatcttcttt ttcatctagt gtataagaga taccgacttc
    31681 cgtcagagca cgtttttgat gatcaagcgc acgcccgatt ccagattttg caagcatctt
    31741 ttcactttca aaatataata ataccttcac cttacgtccc ccttcactta tatagtataa
    31801 catagcctac aaactgtcac tcaaacttaa gccctatttt tgtctattct tactgacaaa
    31861 aacgttttct taaaaaagaa caaaaaaact ggcgtagctc ttttacaagc cacaccagct
    31921 tttgatacgt tgtttatttt acatattcat gaacaagttc aacgacttct tccatcatat
    31981 cgcattcttt caatgcacga tcagcaagtt cagccatttt cgctgtgtcc aagcgtttca
    32041 ttaaactacg cgttttaaga atagatgtcg cactcattga gaactcatct agacccatac
    32101 ctactagcaa tggaacagct gtttgatctc cagccatttc tccacacata cctgcccatt
    32161 ttccttcagc gtgtgctgca tcaattacat ttttgatcaa acgtaaaatt gatgggttat
    32221 atggttggta caagtaagaa acgcgttcgt tcatacggtc tgctgccatt gtgtattgaa
    32281 tcaaatcgtt cgtacctaca gagaagaaat ctacttcttt tgcaaacttg tctgctaaga
    32341 ctgctgctgc tggaatctcg atcatgatgc cgacttggat cgtatcagat acttccttgc
    32401 cttcacttat caatttttgt ttttcttctt caaagatcgc ttttgctgcg cggaattctt
    32461 tgagtgtagc taccataggg aacatgatac gtaaattacc atgaacagat gcacgaagca
    32521 atgcacgcat ttgtgtacgg aacatttcgt cgccttgttc agataaactg atacgcaatg
    32581 cacgatatcc taagaatgga ttcatttcat gaggtaattg cagatatggt agttctttat
    32641 ctccaccgat gtccattgta cgaacaacta caggttttcc ttccatacct tctaatacag
    32701 ctttgtaagc ttcatattgg tcatcttctg ttgggaagtc tggagaatcc atatacagga
    32761 attcagtacg gtacagacca actgcttctc caccattatt atggacacca actagatctt
    32821 ttggtgttcc gatgtttgca gctaattcaa aatgcttgcc gtcagctgtg acagtttctg
    32881 cattttttaa tttttcccat tctgcttttt gtgctgcgta atctgcacct gctttttcaa
    32941 attcagcttt ttgttcatct gtaggatcga tgattacatc gccttcgatc ccgttgacag
    33001 ccaaaatatc gccttctttg actttagcag taatttcttt tgtcccaacg attgctggaa
    33061 tttctaaaga acgtgccatg atagcagaat gtgaagtacg tccaccaatg tctgttacaa
    33121 acgcttttac aaaattgcga tctaattgtg ctgtatcact tggagtcaag tcatgtgcaa
    33181 caacgaccac ttcttcgttg atcattgatg gatttggtaa agtaacgcct aataagtgcg
    33241 ctaaaatacg tttagcaacg tcacgaatat ctgcagcacg ctcttgcata taagcattat
    33301 cttccattgc ttcgaacata ccgatataca tatccgttac ttcttttagc gctgattcag
    33361 catttacgct gttgtcttta atattttgct tgatttgacc taccatttct ggatctgaaa
    33421 gaaccatcaa atgggcatca aatacttgcg cttctgcttc acctaagctt tgcgctgctt
    33481 tttcacgaat ttgctgcaat tcttcagtag atttagctaa tgcagcatcc aaacgagctt
    33541 cttcagccgc agtatcttct actgttgcct tactgaatgt taaatccggt tgaactagca
    33601 ggtaagcttt tgcaacggct ataccgtcac tagcggcaat cccttttagc atttcaacca
    33661 ttattcagat aagccttctt tcttcattgt ttcaacgatt gctgccattg catcagcttc
    33721 gtcagcacct tctgcagtaa tagtaacatc agaaccttga cctacaccta aagacataac
    33781 gcccatgatt gatttcaagt ttactgattt acctttatac tctaagttta catcagagtt
    33841 aaatttgctt gctgtttgta ctaatagtgt agctggacga gcgtggatcc cagtttctgc
    33901 tactacgtga aattctttct tttccatatt aatcggtctc ctttaagtga gtgttgtttt
    33961 tatgtgaggg ttttcttttt tagtaattca gagaatccta acaaatgcca ccctttcatc
    34021 tgtaaagatt aacatttttt ttcgttagat acaacagttt tcattcaatt tcagataaaa
    34081 gtattcaaat tattccggat tctttttcat ccttttcttc acattttata acaaacgtgt
    34141 ttatttcctt tttcttgtcg ctttctcttc tcctgacgtt tatcattctt tcctttgacc
    34201 ctctttgttt tcatatgaaa cgaattactt gcttcccttt ttatttttag tataataaga
    34261 gtcaaaggtc aggaatggtc aatagagatt tcaccttttc tacctcataa atctcttaaa
    34321 aaactagggg ttattctttt acctcatgaa aaacgagatg taaaatatgg atgtacccat
    34381 ttttgtgaaa ggacgtgaat gattcatgct ttgtcaaaac tgcggcaaga atgaggcaac
    34441 gattcacttg tatgccactg tcaatggtca gcggacacaa ctcgattact gtcagagctg
    34501 ttatcaaaaa atcaaaaatc aacaaaatgg aggtctgact aatatggccc aaaatgatcc
    34561 atttggattt ggcagtttgg acgatctttt ccgttccatg tctcgccaaa tgcaacagca
    34621 aggaaattat gagcaaacac caccaacaca atttggcgga aacaacaact tcaatggtgg
    34681 tcagccacct caaggcaata cagaaggttt attgggagaa tacggaatca atatcacaga
    34741 acaagcacga caaggtgata tcgatcctgt gatcggacgc gatgacgaaa tcaaacgagt
    34801 cattgaaatt ttaaatcgcc gaaccaagaa caatcctgtc ttgattggag aaccaggtgt
    34861 tggtaaaaca gcagttgttg aaggtttagc acaaaaaatc gtagatggtg atgtaccgca
    34921 aaaattaatg gacaaagaag tcattcgttt agatgtcgta tctttagtcc aaggtactgg
    34981 tatacgagga caatttgaag aacgtatgca aaaattgatt gaagagatcc gtcaagcaga
    35041 aaatgtgatc ctattcatag atgaagttca cgaaatcgtc ggtgctggtt ctgctggtga
    35101 tggaaatatg gatgctggta atattttaaa accagcttta gctcgaggag aattgcaaat
    35161 ggttggtgct actaccttaa atgagtaccg catcatcgaa aaagacgctg ctttagaacg
    35221 tcgtatgcaa cctgtacggg tagatgaacc aactgtcgaa gaaacgatca gtattttgaa
    35281 aggtttgcaa aaacgttatg aagactatca tcatgtaaaa tatactgatg aggccatcga
    35341 agcagccgca actttatcca atcgttacgt ccaagatcgc ttcttgccgg ataaagccat
    35401 cgatttgcta gatgaaacag gttctaagaa aaacttgacg atccaaatcg ttgatcctaa
    35461 aacaatcgag aaaaaactgc aagaagcaga agaacaaaaa gttttagctt ctcgagaaga
    35521 agatttcgaa aaagcagctt attatcgcga tcagatcaat aaacttcaaa aaatgaaaga
    35581 acgtcagctc actgaagagg aaacacctgt gattaccgaa aaagatatgg aaaaaatcgt
    35641 tgaacaacgg acaggtattc cagtgggtga attaaaagaa aaagaacaga cacaactgaa
    35701 aaacttagca gatgacttga aagctcatgt catcggacaa gataacgctg tagatcgagt
    35761 agcgaaagcg attcgccgaa accgtgttgg attaaacaaa cagaatcgtc caatcggctc
    35821 cttcttattt gttggaccaa ctggtgtagg taaaacagag cttgcgaaac aacttgccta
    35881 cgaactattc ggttcacaag attcaatgat tcgtttcgat atgtctgaat atatggaaaa
    35941 acatagtgtc tctaaattga ttggttctcc tccaggttat gtcggatacg aagaagctgg
    36001 tcaattaaca gaaaaagtac ggagaaatcc ttacagtctt gtcttgttag atgaagtaga
    36061 aaaagctcat ccagatgttt tgcatatgtt cttgcaaatc ttagatgatg gtcgattgac
    36121 agatgcacaa ggaagaacgg tcagctttaa agatacgatc atcattatga caagtaatgc
    36181 cggaactggt aaagtagaag caaacgttgg ttttggtgcg gcacgcgaag gtgttactcg
    36241 ttctgtattg aaccaattaa acaactactt tacaccagaa tttctgaacc gttttgacgg
    36301 gatcatcgaa ttcagtgcat tatcaaaaga aaacttgatg acaatcgtca cactaatgct
    36361 agacgatgtc aaccaaatgc tggcagcaca gcaacttcac atcgaagttc ctacgaatgt
    36421 caaagaaaaa ttagttgact taggctatga tccatctatg ggtgctcgtc ctcttcgacg
    36481 cacgatccaa gaacaaatcg aagatggtat cgctgaattt tatcttgatc acccttctat
    36541 ccatgagttg aaagcaaaac tggataaaga tggaaaaatc atcgttactt ctaaaccaga
    36601 acgtttggct aaagaatcag ccgaagaaac ggctgaataa atccagtttt atagcgtgag
    36661 acggtatttc tttgagaaat gccgtctcat tcttttttca gaaaagtcaa aatactgttc
    36721 attttataaa aaagaaatta taataagaga aacaagcaat taaaaataca taaaagaggt
    36781 gagcgccatg aaattggtaa atgtaacaaa cagccattcc cgtcttgtat taaaccagct
    36841 tgaaaacact gatgcccatc tagtcaaggt ctacacagcc ggaaatacca ctattgtcta
    36901 cactgaagcc cctgaacata atgaaattct gctgatcaat gacaaacgta aaatccagcc
    36961 gaaagaaatc gaagatgcta aaaattattt cttagataaa atcaaagacg ccgtttacca
    37021 cgaggatgaa atcaaagtaa tcgaattggc aggccttgtt gaaatctcga ttccaaaaca
    37081 tgaattaggc gctacattag ccgtgtaaac aaattttgaa cataataatt aaagagcgtg
    37141 ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcgaaagcag
    37201 aagcaactcc ttcggaaata agctgaaatt cacgaaaatt gcttttcaaa tttttgtgaa
    37261 ttccagctta tttcttggag ttaaacgctt ctgtctcagc ctctttttct ttctagcttt
    37321 ttgatttttc tcttttcttt tgtacttttc tcttttcatt ttcagttcta cgcgtgtctt
    37381 tatttttaac tttttcctct ttatggatga ttgatcgtac tttttgtgca atttgctcgt
    37441 ttttgtccca gtcttttaca tctaataatc gacataatcg taacatctct tcttttttct
    37501 gtttttttct ttcacgtctt tgccattctg tttccatgtg tcacactctc ctttctttaa
    37561 tcatatgtac gcaaaataat ttttatattt ttttgattag acatttctat gattttaata
    37621 tagtaaaaag agccgtcacg gaaaatccgt cacggctcta aacaaaatat gagaggctgt
    37681 ttttgtttgg ctattcttat tacttgatgc agggcagctt gtgtcaagac ttctttacat
    37741 caaacttttt aattttacat tgggatattt atccgcaaac cagcgttctg caaattggtt
    37801 ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc aagatattgc gacttgaact
    37861 catcttctca tccaaatctt ctggatcgat ccagcgagcg attttgtgtc ccattggaga
    37921 catgattact tcggcgttat actcatttaa catacgatat tggaatactt cgaattgtag
    37981 ctgaccaaca gctccaatga tatattcttc cgttagatat gttttataaa gctgaatcgc
    38041 tccttcttga actaattgat agattccttt gtggaaggat ttttgtttca tgacattttt
    38101 tgcagtcact ttcataaaca gctctggagt aaatgaaggg agttcttcat aagcaacttt
    38161 tagttttcct tcgaacaatg tatccccaat ctgataattg cctgtatcat atacaccgat
    38221 gatatcgcct gctactgctt tttcgacgtt ttctctcgaa tctgccataa attgtgtgac
    38281 attgcttaat ttcagttttt tatttgtacg ttccaaccag acatccattc ctcgttcgaa
    38341 tgttccagaa cagattcgga caaaagcgat tcggtcacga tgggctggat tcatatttgc
    38401 ttggatcttg aatacgaaac ctgaaaattc ttcctcataa ggacttacca tctgatcatc
    38461 ttgtgttttg tgtccataag gagctggtgc caattcaacg aaagtctcta aaaaagtctg
    38521 tacaccgaag ttagtcaatg cagaaccaaa aaatactggt gtctgatcgc cacgagcaat
    38581 tttttcttga ttaaatgcat ctccagcctc tttgattagt tctacttctt ctaagacttg
    38641 ttcatataag gaattttcag ttagaggatg attttcggga agcagtccat cttcatccaa
    38701 ttctactaat cgttcatcct gataattttc cggacgataa aactctacac gattatggta
    38761 gatatcataa agaccttcta gccctttacc cataccgatt ggccaattca tcggataaga
    38821 ttcgatatct aatagctctt ctaattcttc taacaattcc aatggttcac gaccatcacg
    38881 atctagtttg ttgataaaag taaatatcgg gatgccacgt ttttttacaa cttggaataa
    38941 tttctttgtc tgtgcttcga tcccttttgc actatcgatt accatgaccg cactatccac
    39001 ggccatcaaa gtacgataag tatcttcaga aaaatcttca tgtcctggtg tatccaagat
    39061 atttactcgt ttcccttgat aatcaaactg cataacagaa ctagtaacag aaatcccacg
    39121 ttgtttctcg atttccatcc agtctgattt ggcaaaatta cctgtttttt tgccttttac
    39181 ggtcccggct tgacggatag ccccaccaaa caatagtaat tgttctgtaa tcgttgtttt
    39241 cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga ttgtccactt gttgctttaa
    39301 ttttggatta ttcataacct aactccattt cttccattca attatttata ttttctctag
    39361 gcacagattg tccgatctct taaagaaaga caatttcata tagggctgtg acaaaagccg
    39421 tgtagcagtc tctttttccg agtaaacggc gttctagaga cagcctatca gcaataagcc
    39481 cacccaagcc aaaaatacga aaagctgttt ttgcttggct gctcttatta cttaatgcag
    39541 gatagctttt tcacaacctt tgtcaactac tacaactgaa tcagtatagc atggattcag
    39601 cgaatgaaaa agccaccaaa ccataagagt caaatatttt tttgtcagct gactaaaaga
    39661 aaagacgtgt tgcttgttta ttcaagcaac acgtctttca taaccaagtt tccaattatc
    39721 ttcttggctc gtcatcttcg aattcttttc tgaagtatct tcgttcttct tcaggttccg
    39781 cttctgtttc ttccggatca tgaaaaatga cacggatttt aaggattcga gaaccttcca
    39841 tttcttcaga aaccagcgta atattatcga catcaaacga taacttttcg ccttcatccg
    39901 gaatcatgcc taatgctgta atcaaataac cagccatcgt atctacatca ctcatatgca
    39961 gatcactgtc aaaagcttca ttgaactcat caatcagcat acgtccttgg atgatatatt
    40021 cgtgttcatc gattttttca taaagattct caacttcatc tgattcatca tcgatttctc
    40081 cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc aacgacgccg ccatattcat
    40141 ctaataaaat agccatctga ttctgcgtct ttttcatttc atataacaga tcatcaataa
    40201 agaccgtttc aggaacgaat aaaggctcct gcatgatttt cttgatatct aaattatcaa
    40261 agccgaattt atgggcagct tttagtaaat tctttgtatg aaggattccg actactttat
    40321 ctttgtcttc gttataaaca gggattcttg aatagttttc ggataaaact tcattcacat
    40381 tttcttccac agtgtcgttg atatcaatca taaatgcatc cgttcgtggg accatgactt
    40441 ctcgggcaac tttcgtatca agagaaaaaa ccccttggag catttctaat tcttcattat
    40501 tcaatacgcc ttcgttttca agcatataac gcatttcatc tctggtcatt tttgaatctt
    40561 catcatcaaa agtcatcggc gtgatacgcg ccaataaact tgtggaagca gaaagcagcc
    40621 agacgaaggg cttagctact acaccaatca agcgtatcag ccctgaagtg aactttgcga
    40681 cttcttctga tttatttaaa gcaatacgtt tagggtacaa ttctccaaaa acaatcgata
    40741 cataggtcaa aatagccagc acaatgatat ttgcaatatt ttttgccgct gtgccgccac
    40801 ctaataccgg agctaaccgt tccgataaag tattagctag tgaagcacca gacaaaatgt
    40861 tgaccaaagt gattcctact tggattgtcg ataggaaatt atttggattc tgcaatattt
    40921 ttaaaagctt ttgagatttc acatctcctt catcagcttt ttgctcgatt cgattcttat
    40981 tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc attgatcaat gtcaaaacga
    41041 tcaataataa aatctgcgct aacagcgact gactctcagg gtcagcattc ataatcgcat
    41101 tctctcctta taaaattaat ttttagttta cgatagaaaa aaacgtggca ctatagccac
    41161 gttaaaatgg tatcacaaag caattttctt tgcaataaaa acaagtgtac taaaactacc
    41221 tacgaggtcg tagcaatttt cttcttgttt tcattttgct tgtcttcttt gacgattttg
    41281 attatatagg aaatgatcgt cttgcagatt gcgtaaaaag gaacacctaa gaagatacca
    41341 agcaatccgg caatatttcc agctactaga agaacgataa tgatcgttaa tggatggatt
    41401 ttcagtgatt tcccaattac attaggataa atgatattcc catccaactg ttggacgatt
    41461 agcacaacca cacaacaaag taatgctttt accggatcat tgaagactgt tactagaaat
    41521 gcaggtgcta gtcctagata aggtcctaaa tatggaatta ggtttgtcaa tcccgcaatg
    41581 accccaaata agaaagcata atccacacca attaccatat atcctaaaaa tgtgaaggta
    41641 ccaacgaata aacattcgat tgcttgtccg ctaatgtaat tagccaatgt tttattcagt
    41701 tgccccaata actccacaat ttggtttctt cttttttctg ggaaaaactg ttggatgttt
    41761 ggcactagtt tttctccgtc tttcaacata tagaacaaga tgaatggtgc tgtaatgatt
    41821 actacggttg ccgaagcgat cgttccaacg atcgaaccta aactattgga tactccacta
    41881 aggaattgct gaatgattgt cccgtaagaa atgtctaatt gctcaaaata tttattgata
    41941 tctacttcct tgaacaaagg caattcggct acctctttta accagctttc tacctgtttg
    42001 atgaaatcag gcatattaga tgccaatgag gaaatttgct gtactagact tgggatgaca
    42061 ctaagtaaaa tccaaataat tgctgcaact aaaaggagca gcacaattgc gacagcccat
    42121 attcttttga tttttgcttt catcaacagc ttgacaatag gattcaataa atagtaaaga
    42181 aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa atgtcccgat cggttcgaaa
    42241 ataaagttta tttctgatga aatcatgatc aatgcagcta tgatcaataa ttcaagcgac
    42301 caaaacatta gtttagactg tctaagtttt tcaaacaata gatttcctcc tttctttctt
    42361 actagtatat attatattcg ttaaaaattc ttttattctt tttttatttt tgaaaacttg
    42421 ccatactttt tatttgtttt attttccagt atactatacg aaaggaaggt ggctagacca
    42481 tgaaagttgt acaaacaaaa gatacaatga gcaatattta cttagatgct gtacggatca
    42541 ggcatcaagt ttttgtagtc gaacagggtg tgcctttgtc tcgagaaata gacaaagatg
    42601 aagcccattg tatccacttc gtcctgtact cagataaaaa agaaccgcaa ggaactgtac
    42661 gtcttttgcc tttagaaaac ggaaaaatga aattacagcg gatggcgatt ctttctgaat
    42721 acagacacca agggttagga aaaatattga ttgaagaagc agaaaacttt gctaagaatc
    42781 aaggctataa tacgatttta ttaggggcac agtccacagc tgaaactttt tacgaaaaac
    42841 taggatatac agcttacggc gatccttttg aagatgctgg catgcctcat atttatatga
    42901 aaaagacttt ataaaaattt atttcgaaaa aagcaaaaaa cagcaagctt ttgagaaaa
//
LOCUS       DASHXG010000021        42695 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.021, whole genome shotgun sequence.
ACCESSION   DASHXG010000021 DASHXG010000000
VERSION     DASHXG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.021"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(129..302)
                     /locus_tag="U2R59_001274"
     CDS             complement(129..302)
                     /locus_tag="U2R59_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965679.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            750..3112
                     /locus_tag="U2R59_001275"
                     /pseudo
     CDS             750..3112
                     /locus_tag="U2R59_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3480..4403
                     /gene="truB"
                     /locus_tag="U2R59_001276"
     CDS             3480..4403
                     /gene="truB"
                     /locus_tag="U2R59_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEM8965680.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4407..5348
                     /gene="ribF"
                     /locus_tag="U2R59_001277"
     CDS             4407..5348
                     /gene="ribF"
                     /locus_tag="U2R59_001277"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HEM8965681.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5700..6485
                     /locus_tag="U2R59_001278"
     CDS             5700..6485
                     /locus_tag="U2R59_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8965682.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6498..7349
                     /locus_tag="U2R59_001279"
     CDS             6498..7349
                     /locus_tag="U2R59_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HEM8965683.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7473..7925)
                     /locus_tag="U2R59_001280"
     CDS             complement(7473..7925)
                     /locus_tag="U2R59_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965684.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8390..8758)
                     /locus_tag="U2R59_001281"
     CDS             complement(8390..8758)
                     /locus_tag="U2R59_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HEM8965685.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8908..9390
                     /locus_tag="U2R59_001282"
     CDS             8908..9390
                     /locus_tag="U2R59_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HEM8965686.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9427..10437
                     /locus_tag="U2R59_001283"
     CDS             9427..10437
                     /locus_tag="U2R59_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEM8965687.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10552..11265)
                     /locus_tag="U2R59_001284"
     CDS             complement(10552..11265)
                     /locus_tag="U2R59_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965688.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11455..12045)
                     /locus_tag="U2R59_001285"
     CDS             complement(11455..12045)
                     /locus_tag="U2R59_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HEM8965689.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12529..12756
                     /locus_tag="U2R59_001286"
     CDS             12529..12756
                     /locus_tag="U2R59_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEM8965690.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12772..13938
                     /locus_tag="U2R59_001287"
     CDS             12772..13938
                     /locus_tag="U2R59_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEM8965691.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            14172..15215
                     /gene="hrcA"
                     /locus_tag="U2R59_001288"
     CDS             14172..15215
                     /gene="hrcA"
                     /locus_tag="U2R59_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEM8965692.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15309..15872
                     /gene="grpE"
                     /locus_tag="U2R59_001289"
     CDS             15309..15872
                     /gene="grpE"
                     /locus_tag="U2R59_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEM8965693.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15923..17752
                     /gene="dnaK"
                     /locus_tag="U2R59_001290"
     CDS             15923..17752
                     /gene="dnaK"
                     /locus_tag="U2R59_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEM8965694.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17903..19069
                     /gene="dnaJ"
                     /locus_tag="U2R59_001291"
     CDS             17903..19069
                     /gene="dnaJ"
                     /locus_tag="U2R59_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEM8965695.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19437..20174)
                     /locus_tag="U2R59_001292"
     CDS             complement(19437..20174)
                     /locus_tag="U2R59_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8965696.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(20176..21678)
                     /locus_tag="U2R59_001293"
     CDS             complement(20176..21678)
                     /locus_tag="U2R59_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEM8965697.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            21937..23931
                     /gene="uvrB"
                     /locus_tag="U2R59_001294"
     CDS             21937..23931
                     /gene="uvrB"
                     /locus_tag="U2R59_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HEM8965698.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            23941..26757
                     /gene="uvrA"
                     /locus_tag="U2R59_001295"
     CDS             23941..26757
                     /gene="uvrA"
                     /locus_tag="U2R59_001295"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEM8965699.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            27020..28285
                     /locus_tag="U2R59_001296"
     CDS             27020..28285
                     /locus_tag="U2R59_001296"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HEM8965700.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            28289..29020
                     /locus_tag="U2R59_001297"
     CDS             28289..29020
                     /locus_tag="U2R59_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HEM8965701.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            29155..30039
                     /gene="rapZ"
                     /locus_tag="U2R59_001298"
     CDS             29155..30039
                     /gene="rapZ"
                     /locus_tag="U2R59_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEM8965702.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            30036..31034
                     /locus_tag="U2R59_001299"
     CDS             30036..31034
                     /locus_tag="U2R59_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEM8965703.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            31068..32003
                     /gene="whiA"
                     /locus_tag="U2R59_001300"
     CDS             31068..32003
                     /gene="whiA"
                     /locus_tag="U2R59_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEM8965704.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            32571..33227
                     /locus_tag="U2R59_001301"
     CDS             32571..33227
                     /locus_tag="U2R59_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965705.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            33406..33971
                     /locus_tag="U2R59_001302"
                     /pseudo
     CDS             33406..33971
                     /locus_tag="U2R59_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(34670..35191)
                     /locus_tag="U2R59_001303"
     CDS             complement(34670..35191)
                     /locus_tag="U2R59_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEM8965706.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            35389..39069
                     /gene="nifJ"
                     /locus_tag="U2R59_001304"
     CDS             35389..39069
                     /gene="nifJ"
                     /locus_tag="U2R59_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HEM8965707.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            39258..40145
                     /locus_tag="U2R59_001305"
     CDS             39258..40145
                     /locus_tag="U2R59_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEM8965708.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            40142..41311
                     /locus_tag="U2R59_001306"
     CDS             40142..41311
                     /locus_tag="U2R59_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965709.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            41335..42690
                     /locus_tag="U2R59_001307"
     CDS             41335..42690
                     /locus_tag="U2R59_001307"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEM8965710.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
BASE COUNT        14121 a         7318 c         9218 g        12038 t
ORIGIN      
        1 caggggttgc gggatttttt tgttttcatt aagacgtatt acctaagagt tccatgactt
       61 tagtcttgcg gcgtgtcagc taaccaaaaa agagaaaaag aaaagtaaaa aattcgactt
      121 tcttttttct agtagtatat aaatttttgc atatagataa agatcaagat accgataacg
      181 gaagctagat tgtaatctat tttagtgaca gtcaggtata gccaagtaac tagaagatca
      241 gtggaacctg caccataaaa gtttgagttt gtcggtccgt tgacagttaa aagaaaaatc
      301 acgttgaagt tattgatatt tccgattacg ccgcttcgat ttggtcacga tccaaatttt
      361 ggataatccc tgtagaaatt agcatagtag ctgggatacc aattcacata ttgacaaaga
      421 taacagagac ttttacataa aacggatcaa tcaggaaagg aattgctcga tccagcccca
      481 gttttccagc aatgtgttaa ctggcccagc gtcattcagc aaattatgca tgatgaggag
      541 cgaaatgaac tgcggaacag ccattgtgat aacgacaagt tttttggatc aatgtaaaaa
      601 acgtcagcga aaggaaaaat ttcgtggttt tttatacctg ttcatttggc tagatataaa
      661 atccaaacaa atgaacagaa gtgcttatta ggtttcaatt gggagtatct gcgctagaat
      721 aagagtaata atgaaaagga gtgttatgta tggattattc tagtaaagaa tactttgata
      781 aaatgacggc ttggtggcgt gctgctaatt atctttctgt tgggcaactt tatcttaaag
      841 ataacccctt actgagacgt acactgaaac ccgaagatgt caaaaaacat ccaatcggtc
      901 attggggaac gattcctggc caaaatttta tttatgtcca tttgaaccga gtcatcaata
      961 aatatgattt gaacatgttt tatattgaag ggccaggaca cggcggacaa gtcatggtat
     1021 cgaatgctta tttagatgga agttacacag agatctatcc agaagtaacg gaagatgaga
     1081 caggaatgca aaaattattc aaacgatttt catttcctgg aggcattgct tctcatgcag
     1141 caccagaaac accaggttct atccatgaag gcggagagct tggatactct ctttcacatg
     1201 cagtcggagc tgtattagac aatcctgaag taatctctgc tgtcgtgatt ggtgatggtg
     1261 aagcagaaac cggtccttta gctggaagct ggttctcaaa tgtctttatc aatccagtga
     1321 tagatggagc tgttttaccg atccttcatt taaatggtgc aaaaatagcc aacccaacga
     1381 tcttggcacg taaatcagat ggagaattag caaattactt taacggactt ggctgggaac
     1441 ctttctttat tgaaggaaat gattcagaaa aattaaatcc tgttatggct gaaaaaatgg
     1501 atcaagcaat cgagaaaatt aaatccatcc aaaaagaagc tcgcctgaag acagcaacag
     1561 atgtcgtgat gccaaaatgg ccagtattga tcgtacgcac accaaaagga tggaccggtc
     1621 caaaagaatg ggacggggaa ccaattgaag gaaccttccg agcacaccaa gtaccgattc
     1681 ctgtagatca agaacatatg gatcatgcag atgctttact ccgttggctg aaatcctatg
     1741 aaccagaaaa attatttgat gcacaaggac gtattttaga agaaatcaga gaaatcgcgc
     1801 ctactggtga ccaaagaatg gcaaaaaatc ctatcaccaa tggtggaatc gatccaagac
     1861 cgcttattat gccagattgg aaaaaatata ctttgcaatt tgaaaaacca ggctccgtta
     1921 aagcagaaga tatgaccgaa cttggtaaat tcgttcgcga gatcattgag aaaaatccag
     1981 aaaatttccg tatatttgga ccagatgaaa caaaatcaaa ccgattgaat caagttttca
     2041 aaacgacaaa tcgccaatgg atggaaaaaa tcgaaccaga aaatgatgaa tggctttcgc
     2101 catctggtcg cgtcatcgac agtcaattat cggaacacca agatgaaggg ttcttagaag
     2161 ggtacgttct gactggacgg catggttttt tgcaagttac gaatcattct tgcgagtggt
     2221 tgactctatg ttgactcagc acttcaaatg gatgcggaaa tcacatgacc tttcttggcg
     2281 aaatgattat ccttcgctaa atctcattgc aagctcaaca gtcttccagc aagatcacaa
     2341 tggatatagc caccaagatc caggaatatt gacacatttg gcagaaaaga aggcggagtt
     2401 catccgtgaa tatctgcctg cggatgcaaa tacattgctc gcagtcatgg ataaagcatt
     2461 ccgctcgtca gaaaaaatca atttgatcat ctcttccaaa catccgcgtg ctcaatttta
     2521 ctcagcagaa gaagcagccg tcttagtgaa tgaaggcttg aaaatcattg attgggcttc
     2581 gacagcaaaa gaggaggaac ctgaattggt cattgctgct gcaggaacgg aatctaactt
     2641 agaagcatta gcagctgtaa ctttgctgct ggaagaattc ccaaaactaa aaattcggtt
     2701 catcaatgtc gtagatttat tgaaattacg tcatccaagt caagatccgc gtgggttgag
     2761 cgatgaagaa tttgatcaat attttacaaa agacaaaccg atcttatttg ctttccacgg
     2821 ttatgaaaca ttggtccgca cgattttctt tgatcgtcat aaccatcatt taatgattca
     2881 tggctacaaa gaaaatggag atatcacgac accatttgac atgcgtgtag taaatgaact
     2941 tgatcgttat catttggcaa aagacgcagc tttaaaaatc aaaggaagtc aagcagaaga
     3001 ttttgcgaaa aaaatggatc agaaattaca agaacatcaa aactatattc gtgaaaatgg
     3061 tattgatctg ccagaagtat tggattggaa atggaaaaat cttgaccaat aaaatgataa
     3121 aatcgatccc gcaaaataga attttttaca ttgattaaga aactgaaaaa ataaataaaa
     3181 aaaacggaaa aaagactgga agaatggcca gtcttttttt tcgtttttgg gaagtgaaaa
     3241 ccaaactatt tacctgtaag ccacccataa atccaatcaa atggtgcaaa gaaaaaatct
     3301 tccattctat tccctccttt aaaaaagcat aacatgattt ctatttacgt gagcatgaat
     3361 tttgttacgt ttttattgcc gaaaaataaa aaccgttcat tatgatgtca aattcgtcag
     3421 taattgatgc aatgtgttat aataattcag ttaaatcaaa aatgaaatgg agaaaagaca
     3481 tggacgggtt attaccttta tggaaagaac gcggaatgac aagtcatgat tgcgtattca
     3541 aattaagaaa aatcttacat acgaaaaaaa tcggacatgg gggtacgctt gacccagacg
     3601 tagacggtgt gttgcccatt tgtattggaa aagccacaaa agttatcgaa tatttgacag
     3661 attctgggaa aatctatgta ggcgagataa ctctaggttt cagtacaacg acggaagatc
     3721 gatccggaga acgggtagaa acaaaaccag tagatatgtc tttatctgaa aaaaaaatag
     3781 atgaagtgat ggcttcattt attggtgaga tcacccagat accaccaatg tactcagcgg
     3841 taaaagtcaa cggtaagcgg ttatatgaat atgcccgcaa taatgaaaca gtggagcgtc
     3901 ctgttagaaa ggctcagatt taccgtttta tccggacaag tgaattgaca agagacgaag
     3961 tgacaggaac catttcttgg cgcttcgaag tagaatgcgg gaaaggaacc tatgtccgca
     4021 cattagctgt agatacaggc aagaaacttg gttaccctgc gcacatgtct gatctgaccc
     4081 gaacagcaag tgccggtatg tcccagaagg atgctctgac attagaagaa gtagctcaag
     4141 ctgtgaaaaa tgggacaatc gatgattgtt tgctgccaat agaaaaagga gtggaacggt
     4201 tcaaacgagt agatattact gatgaagtat ggcagaaagt aaaaaacggt atgagacttg
     4261 attatactgt atttgcgctc ccagaaatgc cgtcagaaga aattgctttg ttttataaag
     4321 gaaaagttgt cagtatttat cagccaaacc cgaaagaaaa aaacaaatta aaacctagta
     4381 aagtattgag aaatgaggaa taacgaatga atatcatcaa gatcagacat ccttaccaat
     4441 cagaacaaat tccagaagac gatgtcgttt tagtgctggg atttttcgac ggcgtgcata
     4501 tcggacacca gaaagtcata aagacaggta tggaaattgc acaaaaagaa ggattgaaat
     4561 tagcattgat gactttcaat cagcatccat ctattgtctt taaaaagatc gatcctagca
     4621 gcgtgaaata tttgactagc cttaagcaaa aagaagaaaa aatggccgct ttgggtatag
     4681 attatttata tgaagttgat tttacttctt cttttgctca tttagcaccg caggaatttg
     4741 ttgatcaata catcgtaggg ttacatgcaa aatatgctgt ttccggtttt gattatacgt
     4801 atggaccaaa agacattgca gatgtcgctc attttcctga atatgccaaa ggaagattca
     4861 aaatcgtcac agtttctaaa gaagaagaac aaggtgaaaa aatcagctct acccgtattc
     4921 gtggattact agacagcgga caagtaaaag aagcagcaaa actattaggt tgcacatatg
     4981 aggtagaagg ggtagttgtc catggcgatg cacgaggcag actactagga ttccctacag
     5041 caaatgtcaa agtaaagagc acggttcatt tgcctaaaga aggtgtttat gtgtcggaaa
     5101 taaaaattgg ggaaacatgg tatccagcca tgggttcaat tggacataat gatacattcg
     5161 gtgaaggacg ggagctgact gtagagttgt atattttgga ctttaatcaa gatatctatg
     5221 gtgaacatgt cgcggtacgc tggaatcaat ttttaagaga tcaagtgaaa ttttctagtg
     5281 tagaggaatt gattgaacaa ctcaaggagg atgaacaagc aacagctgaa tatttttctc
     5341 agcaataaaa cattatgcat aaaatctctt gtttatgtat aactagcaat tacaataaaa
     5401 tgggtgataa ataagcccag gaaaggggct gtgacaaaag tcttgtcaca gccttttttt
     5461 ccaaataaat ggtttttcag aagtagcttc ttcggaaata agccgaaatt tcttgaagct
     5521 gaccacttct gtcacaacct ctttctttat agaaataaaa ggacactagc aattcatgaa
     5581 aacgattgct agagcgtatc atttgcttta gactatatat cttggtgtac actcacttta
     5641 aggcggaaat aaaagttatc cgtaataaca ggtttaggta tgaaaaagga gtgggtacta
     5701 tgtacaagga attagaaaac aaagtcgcag tagtaactgg tggctcaaag gggattggaa
     5761 cagcgattgc tcaacgattc gggaaagaaa aaatgaatgt agttgtcaac tataactcgg
     5821 ataaagaagg agcagaaaaa gcagtcaaag caatcgaaga ggcaggcgga aaagcagtct
     5881 ctgtacaagc agatgtcagt tctgaagaag gaatacagcg tttacttgat acggctttag
     5941 aaaattttgg gacactggac gtttgggtta ataatgctgg gatggaaaat cagcatccaa
     6001 cccatgaact tagccttgaa gattgggaaa gagtgttaaa agtcaatttg actggcgttt
     6061 ttatcggaac gaaagcggct ttaaattact ttacagagaa taataaaaaa ggaaatatca
     6121 tcaatatgtc ttctgttcat gaacagatcc catggccaac gtttgctcat tacgctgctt
     6181 caaaaggcgg ggtaaaatta tttaccgaaa cggtagcaat ggagtatgca ccgaagggaa
     6241 tcagaatcaa tagtataggc cctggtgcta tccgtacacc tattaatgcg gcaaaatttg
     6301 atgatcctga acaaaaagaa ctcttggaaa gtatgatccc actaggacgc gtaggtgaac
     6361 caaaagaaat agcggcgaca gctgcatggt tggcttcaga cgaatccagt tatgttacag
     6421 gtattacact atttgcagat ggtgggatga ctttatatcc ttctttccaa ggtggaaaag
     6481 gataagggtg aataaaaatg ggtttattga ttgcattgat cccggcagtt ggctggggga
     6541 tccagccact gattttgaaa aagattggtg gcagaccaac aaatgagata ttaggaactg
     6601 gtattggagc ggtgcttgtc ggcttactcg ttcaattatt cgcttctcca gctggtattt
     6661 cagtgactac atttttgatt agtttacttt ctggtgcatt ttgggttatt ggacaaacag
     6721 gacagtatac atctttcaac ttgattggtg tttctaaaac gatgccaatt tcgactgcat
     6781 tacagttagt cggaacctcg ttgattggtg tcttcgcttt tggagaatgg tctggaagta
     6841 tggggaaaat cattggagca gcagcaatca ttcttcttgt atttggttct gctttaacgg
     6901 caatcagtga tgatcctgga aaaaaaggcg gtatcacaaa aggaattagt ctattagcat
     6961 caacaagtat tggttattgg gtatacagtg cattgcctaa actagttgat gcaagcggac
     7021 tttccatttt ctttccgcaa atgatcggtg tctttttagg ggcagtgatt tatgtgattt
     7081 tccgtaaacc aaccgcattt tctgaagaca agagttggaa agcaacgatc gttggagcca
     7141 tctttagtgt gtcagcattg gcttatattt tttcagcaaa tgaaaatggg gttgctactg
     7201 catatatcat tacacagcta aacgtagtta tctctacatt aggcggtatg tacatcctgc
     7261 atgaaaataa gacaccaaaa gaaaaaaaat taacgattat cggattattg ctgatcgtag
     7321 taggaagcat ggtcacggtc tttatttgag gataaagatg gtaaaatttc atttattaaa
     7381 aaaatatttg tttgaaccaa acagtaagta cttataaaaa aatagcgcta gaatttccaa
     7441 catctctgga atttctagcg ctttttaatt gtttaagata caagggaaat atctgtctgg
     7501 atcaataatt tttcattgat ccattgacta aagtttacga cataattgaa gttaccaccg
     7561 attagtatct ccgcatgatt gtctttataa agatcgtatt gtaaaagacg gtctttttta
     7621 tttgcgtaaa catcgttatg gtactggact aattgttctc ggaattgatt gattgctgta
     7681 aaatcacgat attgaaggtt gaaacgcatc gtgattggtg catttagcat gaatcgctgc
     7741 atttcttttg ctgcttcctc tgcttgatct ccgtatagga actcaaaaag attacgttca
     7801 gaaaatttcc attgcccgcc aacctttgtt ccttttagtt ttccttcatg aagataattt
     7861 ctgatagaac gtgtagtaac acctaattgt tcggctaatt catttactga gtaaaaatct
     7921 ttcaatgttc accctcctat gtgaatggtt ctactgactt agttgatatt tgcttaatca
     7981 cgaaatgtag aaagaacgat tttaattaag gtcattgtaa aaatcaagtc agaaaattct
     8041 aacttttatt tctctaaaga aattcgttct ctcctaaagt gatattatat ttaaatatac
     8101 ctgaaaataa tgggcagtat tatgaaagat cactgatatt ttctcgtatt ttttccttat
     8161 tcaaaagttt tgcaggaaaa ttgctgaaaa aataatttta ctaagtagaa aattcaaagc
     8221 cattcaatca gtgatttttt tcagcacaag aaagactcct tataaaaata gcagatactt
     8281 tgtcaattaa gtgtttaacc agggatgata aaaaggatag gattgaacaa aacctgtata
     8341 aggtgatgaa tagtttcctc gccagtaaaa ggtttattcg tataaagctt tatcgccaaa
     8401 atttatcatg acctttttta tcttcaatat taaatgaaat caattgttca atcaattccc
     8461 agttgattac acttttccaa ggaactttga tgacgttatc cgtatatacg tagcctgctt
     8521 cttggatatt tttttcaagg gcacgaatcg ctgctttttc cggtgcgata gaaaaatgat
     8581 ttttagcaaa actaaatgca ataataaagg taccatggtc agtaaacata ggttggttcc
     8641 attttacagt tgtgtctagc tggggatacg tttctgttat cttagcaaaa aggtctttga
     8701 tcttttgttg atgttctttt tctttgattt gattgatgat cggctgaaat ttttccattc
     8761 taaaacgcct ccattaagtg gtttgattta ttttaccaga aaaacaatag ttatgtataa
     8821 aaaacgaaca aaacacaagt aatgttgtaa ccgctatatt tatatgataa gatgtctcaa
     8881 ataataaaat agaaaagaga cataaaaatg attgacttgg caaagaaatt cttacacgaa
     8941 aatatatatt ttgagttgta tcatcatcga gccatttata caaatgaaga tgctttggta
     9001 ataaagaaag aacaaggatt tacaggtaca gagaccaaaa gcttattctt aaaagataaa
     9061 aaagataata actacgtata tctgactttt actacgaaac aaacggattt caaagcatta
     9121 gggaagatcg tcggtaaaag gctttctatt gtttcatcag aacgcatgga agaacaaacg
     9181 ggacaaaagc agggcgctgt ttctccgttt ggttatgaaa aacagattcc gattattatt
     9241 gatgaagagc tcttatcaaa tgaaaaactt gtttttgcac caggtagacc agatcaaacg
     9301 atggtcatcc aaacggttga cttaaacaaa atcatccagc tacttgagat gccgatattt
     9361 ttgatgccgg caaacgaaaa aaacaattaa ccaagtaaaa tagtgcatac ttggaggtga
     9421 agcaacatga taagttatcc attattagaa agaaatgcaa cgattggggt tactgcacca
     9481 tcctcaggcg tatcagagga acaccattcg ttactcgaat cagctttaaa gagaatggaa
     9541 gaaaaatctt tccaagtagt tactggaaag acgctttgga cgcaagataa ggaaaaatca
     9601 ggtccagcaa gaaaacgagc agatgaattc aatcaaatga tgcaagatga aaatatccaa
     9661 atgatctttc cgacttgggg aggagaatta ttgattgaga ttctcgattt tgtcgatttt
     9721 gatgctctac aaccaaaatg gatagtaggt tattcagata ttagtacgtt gctacttgct
     9781 gtcacattaa aaacagggat agccactgca catggaacta accttattga tttaagagga
     9841 gagtacttgg atgaaacgac agcaatgtgg gaaagtgtac tgaaaacaag agaaggagaa
     9901 tcgattctac agcaatcttc tgaaaagtat caaaaagtgt ggccccatga gcattcatca
     9961 tcttctgttt tccatctcac tgaaccaaca aattggcaat cagtcagcgg agatgcagta
    10021 aggatgaagg gacgattatt aggtggttgt attgatacga tcaggcattt aatcggtact
    10081 ccttatggag atgtccaatc ttttaaaaga aagtataatg atggaaagcc gatcttgtgg
    10141 tttctagaaa actgtgagct atcgtcagtt gatttaagaa gatcacttgt tcagatgaaa
    10201 ctggcaggct ggtttgatgg cagctcgggg atcatgttcg gtagaagtgc ggcagaggat
    10261 ttgttagatt ataaaatgaa ggatgtatac gaagatctgt caaaggaatt aaaactaccg
    10321 atcttgtatg atattgattg tggtcatgta ccgccacaac tgacattgat taatggtgcc
    10381 tatgcagaag tagcggtaga agatagaaaa gcgactgttt tgcaaacgtt tatttaaaaa
    10441 attttttcct gccttggagt ctatcaaaga ccaataaatc taaatagaaa agaaagtgaa
    10501 agaagctgac aaaatgctgt cagcttcttt ttgtataaca tattagaaag tctaattatc
    10561 tataactgtc acatcgatta actgtttcac gtcattggga tttcctgtag gaatagctac
    10621 tacagatgca ttatcaatga tttcttgagt tgtttctcta atgaacgctg gataagatgt
    10681 ttgatctgca ggcatttgcc aatgtgaagg aactggataa ctagtgattg tcccgtcatg
    10741 gttacttgaa tacactaaaa ctccctggta actgtatttc ccagtgagca taaccacatc
    10801 tttcggatag actgcactcc ctgcatcata aggggcgata ggtgttcctg caggataatg
    10861 aataacatgt aattcgaaat cacccgatgt atctctaaaa gtattacctc taatagctag
    10921 ccaaacacgt gcgtactcaa tttgtagatc agaatatcct gctaacggat ctattgactg
    10981 agaagactgt gaggaggttg tgtctattgt tgaagaagaa atatttgtct caactgtact
    11041 actagatgta gaagaagtat tgggctctga gactttactg cttgttgaag atgtattcgt
    11101 ttcagtagaa gctgatttct gagtacttga tttttcagct gaactggttt gtctgattga
    11161 acttttgtct gtggtcgcag atggatcact attttcttta ctaggagacg tacatcctac
    11221 aaggaataaa gagaccaaca ataaaataaa acctaacttt ttcatataaa atacctcatt
    11281 atttttttaa taccagtata gcataatcct gaatttttga atccgtaaaa ccttgtctat
    11341 gaatataaat agagtgtatc ttctttgata aatgtcagaa aaagtgtgac aaataatcat
    11401 cagtaaaatt acttgtcaca ctattgataa ggagtattta attgaagaga atgattagga
    11461 gaaaggatct ccgtactttt tatagtaatc atagaatcca agtttgtata gacgaatcgt
    11521 tttttctctt atttcttctg tttcaaaatg gactgcttga agaatcaagt ctgtgaattc
    11581 tataggagct gttccattcg cagtaatcaa attacgatct ttcacagctt gttgttctat
    11641 aaaatcttct ttattctgat aattttccga ttctaaccaa ggaaattgcg catttccggt
    11701 gtgtttgtaa ccttgcaata atccgctctg agctaaataa tcaactgccc cacaaatagc
    11761 agctactggt acgtctgttt ttaacaattt atcgattatt tgatataaat gatgattttt
    11821 tatgtcccat gaattgccac cgatcataat aaaaaggtca actttttcag gtatttgttc
    11881 gattaagtaa tcgatttttg tttttaatcc tccaatggaa gtgacctctg attggataga
    11941 agcagttttg ttttgccatt tctcattttg gtttagtgtg ctagtaatat aagcaccttc
    12001 ccaatcggca tattcctcta atagaaacgt aatcgcagtt ttcattttca agctctcctt
    12061 tactatctat aacaaggaca acagttttaa cctacagaca ttcattaaaa ttgggtagcg
    12121 acagcgaaaa caacaattct taagttttag acagagtata cagatagtca acttaattaa
    12181 atacgaacta aataaaaatg acaggtaatc atttttgttt accagcatta taacattttg
    12241 catacatgga tgacaaaaga accaattccc acttgcttga gtacaatatt aaaagaaact
    12301 ggaaggcaaa aagtaattat agaaacgaaa aataaatcat atcgggcact cagacatgaa
    12361 aacaacccta gagatatata actaggtaac cagtttaatg aaagaaaaaa tcatccaaga
    12421 agtcgattct tggatttttt agtggatttg ttcgccaaat acgtttagta tgcgtatatg
    12481 agaggttgta agcaaagcgt tgtggtctga gcacttaagg aggaatctgt gaaaatagct
    12541 tttcatattt ttgcagattt tgacttaatg ccgaaggtca gctttgcgat taccgtttat
    12601 cgagaggctg taaaagcacc gtgtagctcc gatgacaata agcaagcatt tttagagcta
    12661 ggtttccttg attctaaata tgcggcttat ttcaatgagt tggtgcttga acgcgatttt
    12721 aagaaggtcg aaaacaggca cgacttttcg acgtaaggag aaagaatttc aatgatagaa
    12781 acaataaatc ccgcagaaaa caaggtttct gcgtacattc atatcccatt ttgcgagcat
    12841 atctgctatt actgtgattt taataaagtt tttttagaag ggcagccagt agatgagtat
    12901 gtggaaatgc tgctgaatga aatgaaaata atgctagaaa gtcatccgac agcgaattta
    12961 gaaacacttt acgtaggggg cgggacacca acttctttat ctgctaaaca acttgatcga
    13021 ctgttatcag gtgctagaga gatcctgcct tttcaaaatg gtaatgagtt tactgtagaa
    13081 gcgaatccag gtgatttgac ccgtgaaaaa cttcaagtaa tgaaaaacta tggcgtcaat
    13141 cgtttatcca tgggagtgca gacatttgat aatcgcttat tgaaaaaaat tggacgtaaa
    13201 cacaccgcag aagatgtgta tcaaactatg caatttttag aagcagaaaa ttttaccaat
    13261 gtaagcatcg atttgattta tgcattaccg ggacaaacac tagaaggata tctggatact
    13321 ttggaaaaag ctttggcttt ggatctgcct cactattctt tgtactcatt gatcctcgaa
    13381 aacaaaacaa tgttcatgaa ctgggtacga caaggaagac tcgaactgcc tgatcaggaa
    13441 acggaaacca gaatgtttga agagacgatt gaagcaatgg aaaagcatgg acgtcaccaa
    13501 tatgaaataa gtaactttgg gctctccgga catgaatctc aacataacct catgtactgg
    13561 aacaatgccc actattttgg gtttggagct ggtgctagcg gttatcttgg agatattcgt
    13621 taccgcaaca aaggaccaat ccaacactat ttacgcccat tacgagcaaa tgaacgcccg
    13681 gtattggaag aagaaaaatt gacacgaaaa aatcaaatag aagaagaaat gttcttagga
    13741 ctaagaaaaa aaacagggat tactaaaaaa catttctatg atcgctatca aaaaacaatt
    13801 gaatcggtgt acggtgatgt gctaagggaa ttagagcaag aagggttact tgttaatgaa
    13861 gaagaccgtg tttatttgac accaagaggg acctttttgg ggaacaatgt gtttgagcgc
    13921 tttttgtttg aaaaatagtt taaagaatat ttgtttttta tctgaattta aataaaaaaa
    13981 gttcaaaaat acaataaagg actattgaaa cgttgatata actggattta catcaattat
    14041 ttagaattag cactcttgtg tttagagtgc taaaaaatgg agtctttctc ttgacaggag
    14101 aagggcttct tgctatattt ataagtggat tagcacttag aatatatgag tgctaatgag
    14161 aggtgaggaa gatgttaaca aagcgacaaa acgacatttt acgtctgatc atccaacact
    14221 atacgagtag tggcgtgccc gttggttcca aaacattgat gtctgaggga gtcaaggcca
    14281 gctcagcaac gattcgcaat gatatgaaag cattagaaga tgaaggattg ctgttgaaga
    14341 ctcactcttc ttctgggcgg attccatctg ctttaggcta tcgttattac gtggatcatt
    14401 tgttaaaacc tgctcgcgta gcagaagatg atttgctgct gattcgtcag tctctaggca
    14461 gagaatttca tgaaatcaat gagattatta agcaatctgc tgagatatta tctgagctga
    14521 caagctatac gactttttca ttgggacctg aaataaaaga ccgccgactg actggctttc
    14581 gtatcgtacc cttgaataat cgacagatta ttgctatcgt cgtaacagat atggggaatg
    14641 tagaaagcca agtgttcact cttcccgaat atatgggaag tcaggaacta gaaaaaatgg
    14701 tacagattgt aaacgaccgt ctagtcggag atcctctgat gacggtgtac cataaacttc
    14761 gtacggagat tccgatgatt cttcataaat atttccaaac gacagaaggg atgtctcagt
    14821 tatttgacac cgttcttggt catgtttttg aagataaggt ttatgtcagt ggacaaatga
    14881 atctcttgga ttatgagccc cgtcaagatc ttgatcagtt caaatcgatg ttttctttta
    14941 tgaaagactc agacggactt acacaaatga tcactccgat ggatagcaat attcatatca
    15001 agattggtgc tgaattaggc aatgatttat tgcagaatat gagtatgatt caagcaagtt
    15061 acgagataga tggtcatgga agaggtacaa tagccttgtt agggcctact agtatgcctt
    15121 attctcggat gttcggtcta gtcgatgttt atcgaagaga actagcagct aaacttgctg
    15181 attactaccg ttcgcttgac ttgtcaaact cgtaatgtga ataacgaagc tatttgcagc
    15241 tgatcgttct ctctttctta gtaagagcaa tcaaacagct gactgaataa tgaaaggaag
    15301 actgtatcgt gaaagaaaat caagaagaac tagataaaga aatgacagat gctcagccag
    15361 aaccggaaat cgatgtcgaa gctgcagaag attcgggtat ttcagaagct gaagcggaag
    15421 aattcgaaac agcgaaatta aaagctgagt tagaagaaat ggaagataaa tacttgcggg
    15481 ctcgtgctga aatcgcaaat atggcaaatc gaggaaaaaa tgagcgtgag caattacaaa
    15541 aataccgttc acaagattta gccaaaaaat tacttccatc aattgacaac ctggaacgtg
    15601 cattagccac agaagtgtca gatgatcaag gggcaggttt gaaaaaaggc gtggaaatgg
    15661 tcttggaaag tttgcgtaac gcactggaag aagaaggaat tgaaaaaatc cctgctaaag
    15721 gagaagcctt tgatcctaat cttcatcaag cagtacaaac tgttccagcg actgaagata
    15781 caccagccga tacgattgta gaagtactac aagaaggcta caaattacat gatcgcgtgt
    15841 taagaccaac catggtcatt gttgcacaat aattgtgcgg atataaaact tacactttca
    15901 attaaagaag gagacgttaa ttatgagtaa aattatcggt attgacttag gtacgactaa
    15961 ctctgcagta gcagtattgg aaggaaacga agcaaaaatc atcgctaacc cagaaggaaa
    16021 ccgtacaaca ccttctgttg tatcattcaa aaatggagaa atccaagtag gggaagttgc
    16081 aaaacgtcaa gctgtgacaa acccaaatac gatttcatca atcaaacgcc atatcggtga
    16141 agcaggttac aaagtagatg tagaaggtaa atcatataca ccacaagaaa tctcagcaat
    16201 gatccttcaa tatatcaaag gattcgcaga agactattta ggtgaaaaag tcgaaaaagc
    16261 agttatcact gtgccagctt actttaatga tgcacaacgt caagcaacaa aagatgctgg
    16321 taagatcgct ggtctagaag tagaacgtat cgtcaatgaa ccaactgcag ctgctcttgc
    16381 ctatggttta gataaaacag atcgcgacga aaaaatctta gtattcgacc ttggtggcgg
    16441 tacttttgac gtatctatcc ttgaactagg agacggtgtc tttgatgtat tgtcaacagc
    16501 tggcgacaac catctaggtg gggacgactt tgataacaaa atcatcgact acatggtagc
    16561 agaattcaaa aaagaaaaca gcattgactt gtctcaagac aaaatggctt tacaacgctt
    16621 gaaagacgct gctgaaaaag cgaaaaaaga tttatctggc gtatcaagca cacaaatcag
    16681 cttgccattt atcacagcag gagaatctgg accattgcat ttggaaatga cattgacacg
    16741 tgcaaaattt gatgaattaa cagctgactt agtagaacgt acaaaagtac cagtacgtca
    16801 agcgttaaaa gatgcaggtc tgtcacaatc agaaatcgac gaagttattt tagtcggtgg
    16861 atctactcgt atccctgcag ttgtagaagc agtacgtaaa gaaacaggaa aagaaccaaa
    16921 caaatcagtt aaccctgatg aagtagttgc tatgggtgct gctatccaag gtggcgtgat
    16981 cactggtgat gtgaaagatg ttgttttact tgacgttaca ccattgtcat taggtatcga
    17041 aacaatgggt ggagtgttca ctaaattgat tgaccgcaat acaacgattc caacaagtaa
    17101 atcacaagta ttctcaactg cggcagataa tcaaccagca gtagacatcc atgtattaca
    17161 aggtgaacgc ccaatggctg ctgacaacaa aactctagga agattccaat tgacagatat
    17221 tccagcagct cctcgtggta ttccacaaat cgaagtaaca ttcgatattg ataaaaacgg
    17281 gattgtaaat gtatctgcga aagatctagg tacacaaaaa gaacaaaaaa tcacgatcaa
    17341 atcttcttca ggtctaacag acgaagaaat cgaacgtatg gtgaaagatg cagaagcaaa
    17401 cgctgaagca gataaagctc gtaaagagga agttgaccta cgtaatgatg tagacgcatt
    17461 gctattctct gtggacaaaa cattgaaaga attagaaggc aaagtggacg aagaagaagt
    17521 gaaaaaagca gaaacagctc gtgacgaatt aaaagccgct gttgaagcaa acaacatcga
    17581 ggaaatgaaa actaaacgcg atgcattgaa cgaaatcgtt caaaacttga ctgttaaact
    17641 atacgaacaa gctgcacaac aacaagctca agaaaatcca gaagcagctc aaggcggagc
    17701 agatgatgtc gttgatgctg attttgaaga agtcgatggc gacgataaat aatcagttca
    17761 ctgaatttcg agagaaggcc aaagttgcta ctttggcttt ttcttttgaa aaatagtttg
    17821 aagtatcggt ttttgtttca aacaaaatat gatatgataa caagcgacgt gaaaatgatg
    17881 agaaccaata ggaggaaagc ctatggcaac aaaacgtgat tattatgaag tcttagggct
    17941 ctcaaaagga gcatcagaag atgaaataaa gaaagcttat cgtaagcttt cgaaaaaata
    18001 ccatcctgac atcaataaag aacctgatgc ggaagaaaaa ttcaaagaag tatcagaagc
    18061 atatgagatt ttaagtgacc cgcaaaaacg cgctgcatac gaccaatacg ggcatgcagg
    18121 cacagatcca aattacggtg ctggtggagc tggtggcgga tttggtggat tcggcggctt
    18181 ctctggtggc ggcttcggtg gttttgaaga tatcttcgac tctttctttg gaggaggcgg
    18241 tcggtcagtc gatccaaatg cgcctcgtca aggtgctgat ttgcaatata cggtcgactt
    18301 gtcttttgaa gaagcgattt ttggtgtaga aaaagaaatc aagtataatc gggaagaaat
    18361 ctgtcatact tgtggtggaa acggtgcaaa accaggcaca caaccaacta cttgtcataa
    18421 atgtcatggt gcaggtacga tcaatgtaga acgccaaacg ccacttggac gagtgatgag
    18481 ccgtcaaact tgtgatgttt gtcatggcac agggaaagaa atcaaagaac cttgtccaac
    18541 ctgtcatggc tcaggacatg agaagaaagc acattcagtt aaagtgaatg taccagctgg
    18601 tgtagaagaa ggacaacaaa tgcgtttagc tggtcaagga gaagctggag aaaacggcgg
    18661 accatttggt gatttgtatg tggtttttcg tgtagaagaa agtgatatct ttgatcgtga
    18721 aggttctgaa atttactatg aattgccttt aagttttgta caagcagctt tgggggatga
    18781 agtccaagta ccaactgtcc atggagatgt gaaattgaag atccctgctg gaacacagac
    18841 aggtacgaac ttccgtttac gtggaaaagg cgctccgaag ttacgtggtg gtgcaacagg
    18901 cgaccaacat gtcaaagtaa aactgatcac accgaaaaat ctaaatgaac aacaaagaga
    18961 agcattacgt gcattcgctg aagctggcgg catcaaagtt gaagaacagc aagaagacgg
    19021 tttcttcgat aagtttaaag atgcttttgg cgggaaaaag cggaagtagt ttttctagta
    19081 aaaatataaa gtagacttgc ccaaattttc tatttctagt aaaaacgcta agtcattaat
    19141 aattaaaaac cagacgaaca atcatacgtt cgcctggttt ttttgtagtt gtcatgtttg
    19201 taccaacaaa aaagccagct ttagaataag ataatcatca tagtttctga aggtggtatc
    19261 gactatgtac ttgatatcgt caatgaaccg atggtacttt cttatgcgat ggaacaggta
    19321 gagcgattgc ttgtttgtgc aggagaacaa gcgatgcggc tggtacagtt aagtgaaaaa
    19381 acaagaaact aaaaatgccc ggtcgtcatg aagcgaccgg gcatttttgg tttttattaa
    19441 atatttaata ctttattcaa gaaatctttt gtccgttcat tttgcggatt ttcaaagatt
    19501 tgttgaggcg ttccgtcttc taaaaagttt ccgtcgtcaa tgaacatgac acgattggcc
    19561 acttctttag cgaagcccat ttcgtgcgta acgataacca tcgtcatacc ttgttctgct
    19621 aactttttca tgacgttcaa gacatcaccg accatttcgg ggtcgagtgc agatgtaggc
    19681 tcatcaaaaa gcatgatgtc agggttcatc gctagagcac gagcaatagc cacacgctgc
    19741 ttttgtccac cggaaagcat ttcaggatac atatcttttt tatcttctag accaactgtc
    19801 tgcagcaatt tgattgcttt tttctctgct tcttctctag attctttctt caggtccatc
    19861 ggtgctaaaa tgatgttttc caaaatagaa agatgaggga ataggttaaa gtgctggaat
    19921 accattccga tatgttgtct caccaagttg atatctgtgc ttttatccat caagtgggcg
    19981 ccgtcaataa taatttcacc gtcagaaggt tcttctaaac gattcaagca acgcaaaaat
    20041 gtactttttc ctgaacctga agggccaatg atacagacga catctccttc gttgatggac
    20101 acattgatgt cgtttaatac tgtgttatcg ccgtattttt tgactaaatg ctcaactaag
    20161 attttttctg ccatcttact tcaccttctt ttctaaaact tttgctaatt ttgtcaatgc
    20221 tgtgatcaaa atcaagtaca tgatcgcaat gatcaagtaa acatacgtac tttgtgttgt
    20281 acgtgcaaca atgatcttac cagtttgcag caattcgact acaccgattg cggaaatgat
    20341 cgttgtgtct tttaatgaga taacgaactg attgacgaat gatgggatca tgatgcgtat
    20401 cgcttgcggc aaaatgattt tttgcattgt ccgattataa gaaagaccta aacttctgga
    20461 agcttccatt tgtccgacag gaacggcgtt gatcccgcct cgaacaatct ctgcgatata
    20521 agcacttgcg ttaagagtca aggtgataac accagcaagg aagtcaggaa tcgtaaatcc
    20581 aacgatacca ggcaacccaa agaaaataaa gaacgcaaga accatcattg gaattcctcg
    20641 gatgatatcg acataaatac tagcaattgt gcgaagagcg cgtattggtg ctacactgaa
    20701 taatccaaaa atcacaccga ttactatagc caaagcaaag gagatcaaag ttaggagaat
    20761 tgttctccaa agtcctttca acaatgcttg atagttgttt tggataagtc caagaaatgt
    20821 tgattcatca gcagtggaag actcactgga agtttctgaa ccatccgcta catattcttt
    20881 aataatctta tcgtattcgc ctgttctttt taattctttc aatccttcat tgaacatatt
    20941 aagaagctca ggattttgtc cttttttaac ggcaaatgca tattttccgc cagattcttt
    21001 tttgatcggt gtttccaatt cttgtccttg tttgatcgca taaccgatta ccggataatc
    21061 atccatcatt gcatcgattg cgccaacttt taacccgtcg tacaattgat cagcagcatc
    21121 aaaatatttg atagaatagc catattcaga ttcatggtcg cttaaaaatt cagcactttc
    21181 ggtaccaact tttgctccga ctgtttttcc tttcaaatct tcataagact tgatcgaagt
    21241 atctcctttt ttgacagcta attggatccc gctatcaaag taagaatcag aaaaatcata
    21301 gcttttcttt cgttcatctg ttacagtcat tccggcaatc attccgtctg cttgtcctga
    21361 ttccaaagct tgcaaagcag cagagaaacc acggtagtcc attcggatgt taaatccttg
    21421 cagtttggcg atgttttcca tcaattttac atcgatgcct tcgtactcgc cctttgcgtt
    21481 ttgaaattca aatggagcaa aagcagagtc actggcaatt acgtatacgt cttttttggg
    21541 ctctattttt tgcattgtct cgcttgtgct tgactctgcc gttgtagtgt tgtcagcttg
    21601 tgcaacatgt ccaaacgcaa gtgtcacaag tcctgtcatt aagaaaacaa atgagtgaaa
    21661 taaatgcttt cttttcataa tcaacctcct aaatttccaa tattttatta ttataggcga
    21721 aaagtgctga atcagacaag actgtaagct cgaaaaaatg aaaaaaatgc gagtttctaa
    21781 cattttatgt tataaaacgt aacatgcata ataagataaa aaagtggcga aagtatgttc
    21841 ggtgtggtat aattttttag taaggaatgc ctttgctttc cttttctttt tattggtcgt
    21901 aaaatgaaaa ggaatgaatg aaaaggagga cgaagaatga ttgagagaga tacctcccga
    21961 cactttgagc ttgtctcgaa ataccaaccg gctggtgatc agcctgaagc gattaaccaa
    22021 ttagtggatg gcgtagtcgg cgggaaaaaa gcacaaatct tattaggtgc gactggaaca
    22081 gggaaaacat atacgatttc caatcttatt gagaaagtga ataaaccaac actaattatt
    22141 gcccataaca aaacattggc tggtcagctg tacggggaat tcaaggaatt tttccctaac
    22201 aatgctgttg aatattttgt ttcttattat gattattatc agcctgaagc ttatgtgcct
    22261 tcaagcgata cgtatatcga aaaagattca agtgtaaatg atgagatcga caaattacga
    22321 cattcggcta ctagttcatt attagaaaga aatgatgtga tcgtcattgc atccgtttca
    22381 tgtatttttg gattaggttc gccttttgag taccaaaaac aagtagtttc gattcgacag
    22441 ggagcagaac tagatcgcaa tcagttgatt cgtgacttag tcagtatcca attcgaaaga
    22501 aatgatatag attttcagcg cggtcgtttt cgagtgcgcg gtgatgtcgt ggagattttt
    22561 ccggcttcaa gagatgaacg tgccttacgt gtggagtttt ttggagatga ggtcgaacgt
    22621 atccgagaag tcaatgcact gacaggtgaa gttttaggag aaacggaaca cgtggcaatc
    22681 ttcccggcga ctcactttgt gacgaatgat gaacatatgg agcatgccgt agcgaatatc
    22741 aaagcggaat tagaacagcg tttaactgtc ttgcgaaatg aaaacaaact tctggaagct
    22801 caacgtttag aacagcgaac caattacgat attgaaatga tgttagaaat gggctacacg
    22861 tcgggaattg aaaattattc tcggcatatg gacggacgta aagaaggtga accgccttat
    22921 acgctattgg atttctttcc tgaagatttt ttgatcgtgg cggacgaatc gcacgtaacc
    22981 atgcctcaag tcagaggaat gtataatggt gaccgagcga gaaaacagat gctagtagat
    23041 tacggtttcc gtttgccatc tgctttagac aatcggccac ttcggttaga agagtttgaa
    23101 aaacatgtca atcagatcat ttatgtctct gcgacgccag gaccatatga acatgaacaa
    23161 acagataccg ttatccaaca aatcatccgt ccgacagggc tgcttgaccc agtgatcgaa
    23221 gttcgtccaa tcatgggaca aatcgatgat ctagtaggcg aaataaatga acgagtcgaa
    23281 aaagaccagc gggtgtttgt aacgacattg acgaaaaaaa tggcagaaga cctcacagat
    23341 tatttcaaag aattagggat caaagtcaaa tatttgcata gtgatatcaa aacgctggaa
    23401 cgaacagaaa tcattcgaga tcttcgatta ggtgaatttg atgtgttagt tggaatcaat
    23461 ttgcttcgtg aaggattaga cgtacctgaa gtttcccttg ttgctatctt ggatgcggat
    23521 aaagaaggct ttttacgtag tgaacgttcc ttagtccaaa cgattggacg agctgctcgg
    23581 aatgaagaag gtaaagtaat catgtacgca gacaaagtaa cagattctat gcgtctagcg
    23641 atggatgaaa catcaagacg ccgtacgatt cagcagaagt acaatgaaga acatgggatc
    23701 gttccaaaaa cgatcattaa agaaatccga gatttgattt ctattacgaa agaatcggaa
    23761 gatgatacaa aagaagcggt acaagtctcg tatgaagaaa tgacgaaaga agaaaaagat
    23821 acgttattga tgaaattaga aaaagaaatg aaaaatgcgg cgaaagcatt ggattttgaa
    23881 acagccgcta atgtgcgaga tatgatttta gaattaaaag cttcaaagta ggaggacaac
    23941 atggctaacg ataaaattac gattcacggt gcacgtgccc ataacttgaa aaatatagat
    24001 gtaacgattc cacgagataa attcgtggtc gttacaggtt tgtccggttc tggaaaaagt
    24061 tccctagcat ttgatacgct gtacgctgaa gggcagcgga gatacgtaga gagcctttct
    24121 gcttatgctc gtcagttttt aggacaaatg gataagccgg acgtagatag catcgacgga
    24181 ttgagtccgg cgatttctat tgatcagaaa acaacaagta aaaatcctcg gtcgacagta
    24241 ggtactgtga cggaaatcaa tgactattta cgcttgttgt ttgcacgtgt aggacatccg
    24301 atttgtccca acgatcatat cgagattacc agtcaatcag tagatcaaat ggcagatcaa
    24361 gtaatggctt tgcctgagcg cacaaagatc caagtgttgg caccgatcgt ggtaaagaaa
    24421 aaaggacaac ataaaaaaat attcgaacga atccaaaaag agggatacgt ccgcgttcga
    24481 gtcgatggtg agatctatga tttaagtgaa gtgcctgagc tggagaaaaa caaaaaacat
    24541 gatatcgcga tcgtcatcga ccggatcatt gtgaaagaag ggattcgttc tcgtctattt
    24601 gattctttag aggcggctct gcgattggca gacggctatg ctctggttga cgtgatcggt
    24661 gaagaagaaa tgttgtttag cgaacactat gcctgtcctt attgcggatt tactgttggc
    24721 gaactagaac caagactgtt ctcattcaat gcgccttttg gagcttgtcc agactgtgat
    24781 ggtttaggtg tcaaattaga agtcgatcaa gatttagtga ttccagatag aacgaagaca
    24841 cttagtcaag gtgctatcgt tccatggaat ccaatcagct ctcagtatta tcctcaaatg
    24901 ttagcgcagg cttgtgaaag tttcggtatc gatttagata caccattcga agaattaccg
    24961 gaagagcatc aggatatcat cttgaatggg acagatgatc ttttccattt ccattatgaa
    25021 aatgattttg gtggcgttcg cgatgtagaa acgactttcg aaggggtatt gaagaatatc
    25081 gagcgtcgtt atcatgatac gaacagtgat ttcacgcgtg agcaaatgcg tctttatatg
    25141 acagaattaa cttgtcagac atgtaaaggt tatcgattga atccccaagc tctatctgtt
    25201 caaatcaatg gaacgaatat cgggcaaaca aatgagttgt ctattcaaaa agcagtagat
    25261 ttcttctcaa acttaacgtt atctgaacaa gagaaagtaa ttgccaaacc gattttaaaa
    25321 gaagtaaatg acagactttc attcttggaa aatgtgggac tagactatct aactttgagt
    25381 cgcgcttccg gaacattatc tgggggagaa gcgcagcgaa tcagattggc tacacaaatt
    25441 ggatcgaatc tttctggagt tttgtatatt ttagatgaac catcgatcgg attgcatcaa
    25501 cgcgacaacg atcgactgat tggctcatta aagaaaatgc gtgatcttgg caacaccctc
    25561 gttgtagtcg aacatgatga agatacgatg tgggcagcag attatctgat tgacgtcgga
    25621 cctggggccg gagaacaagg cggacaaatc gtggctgcag gcactcctga agaagtagct
    25681 aatgatgaaa attctttgac agggaaatat ctttcaggga aaaaatcaat ccctgtacca
    25741 aaagaacgcc gtaaaggtaa tgggaaagca atcaagatca ctggtgcttc agaaaacaat
    25801 ctgaaaaata ttagtgttga atttccatta ggagaatttg tagcagtcac aggtgtgtct
    25861 ggttctggaa agagtacatt ggtcaatagt atcttaaaga aatcgttagc gcaaaaatta
    25921 aataagaatt ctgctaagcc aggtaaattc aagacaattt ccggctacga aagtatcgaa
    25981 aagatcatcg atatcgatca aagcccaatc ggccggacgc cgagaagtaa tccagcgact
    26041 tatacaagtg tatttgatga tatccgtggg ttatttgctc aaacgaacga ggcaaaaatg
    26101 cggggttata agaaagggcg ttttagtttc aacgtaaaag gcggtcgttg tgaagcttgt
    26161 cgcggggatg gaattattaa gatcgaaatg cactttttgc ctgatgtcta tgttccttgt
    26221 gaagtatgtc atggcaaacg atataactct gaaacattag aagtgcatta caaaggaaaa
    26281 agcattgctg atattttgga aatgacagta gaagatgctg tagaattctt caagcacatt
    26341 ccaaagattc atcgcaaact gcaaacgatt gttgatgttg gcttaggtta tgtgacgatg
    26401 gggcaaccag caacgacatt gtccggtggt gaggcacaac ggatgaaact tgccagtgaa
    26461 ttgcacaaaa tctctaatgg aaagaatttc tatatactag atgaaccaac gacaggactt
    26521 catagcgatg acatcgcccg cttgttgcat gtattacaaa gattagtaga tgctggtaac
    26581 acagttttag tgattgaaca caatctagat gtaatcaaaa cagcagatta tatcattgat
    26641 ttaggaccag aaggtggaga aggtggagga acgatccttg cgactggaac accagaagaa
    26701 atcattaacg taaaagaaag ttatacaggt cactatttga aaaaaataat ggtataaaga
    26761 ggatagatag ctgagatagt taaaaaaaca taaaaaaatg aatttttgct tgttttatta
    26821 atatcagtgt tctagaatca ttacatggta gttctttcta cactgattgg tatagacaaa
    26881 aacttcctat aagttcaatc cgttcaaaaa agaattgagc aatcggagga gtttcctttg
    26941 attgcttttt tctttatggt atgatattcc ttgtgtagtt ggaaaagaaa aacaagagat
    27001 tatgagtaag tgagagataa tgatgaacag tattgaaaat gaagaattta tccctatatt
    27061 attaggaagc gacatgaacg tttatggtat ggcacgttct tttaatgaag catacggcaa
    27121 aatctgccaa gcatatgctt cggatcagtt agcccctacc cgctacagta aaattgtcaa
    27181 tgtagaagtt attccaggat ttgataaaga ccctgtgttt atcgagacga tgcttcgttt
    27241 ggcaaaagaa agatattctg ataagagtaa aaaatatctt ttgattgctt gtggtgatgg
    27301 atatgcagaa ttgatctccc aacataaaca agagctgtca gaatatttta tctgtccata
    27361 tattgattat tctttatttg aaagactgat caataaagta agcttttatg aagtttgtga
    27421 agaatatgat cttccgtatc ctaaaacatt gatcgtcaga gaagaaatgt tagtaaatgg
    27481 acatttggaa caggaattgc cttttgaatt cccagttgct ttgaaacctg caaacagtgt
    27541 ggagtatctt tctgtccaat ttgaaggaag aaaaaaagct tttattttag agactagaga
    27601 agagttcgat ttaattttag gccggatata cgaagccggt tataaaagtg aaatgattgt
    27661 acaagatttt atcccgggtg atgatagtaa tatgcgtgtg ctaaatgcgt atgtagatga
    27721 agatcatcaa gttcggatga tgtgtcttgg tcatccactg ttagaagatc ctacaccagc
    27781 atcgattggt aattacgttg tgatcatgcc agattataac gaaaaaatct atcaaaccat
    27841 taaggcattt ttggaaaaaa tcgaatatac aggctttgcc aatttcgata tgaagtatga
    27901 tcctagagat ggagaatata aattatttga aatcaatttg agacaaggtc gtagcagttt
    27961 ctttgtgaca ttgaacggct tgaatctggc tcgtttcgtc acagaagatc gagtgtttaa
    28021 caaacccttt gttgaaacga cctatggaac gaatcaatca gataaagcaa gattatggat
    28081 gggtgtgccc aaaaaaatct ttttagaata tgctcgggaa aatgaagaca aaaaactagc
    28141 tgagcaaatg atcaaagaaa atcgttacgg tactactgtg ttttatgaaa aagaccggtc
    28201 aatcaagcgc tggttgttga tgaaatatat gttccataac tatattccaa gattcaaaaa
    28261 gtattttcat gtgaaagaag gctagttcat ggagaatttt ttcagtattt taggcggaat
    28321 gggcacgatg gcgacagaaa gttttgttcg cttgatcaac caccgaacga aagctacaaa
    28381 agatcaagaa tatttgaatt atgtcttatt caatcatgca acagttcctg atcgtacagc
    28441 ttatatttta gatcgatcag aagaaaatcc aatgccgttt ctgctggatg atattgagaa
    28501 acaaaattta ttgcagccga acttcattgt gttgacttgt aacaccgcac actacttttt
    28561 tgaagaatta caagcggcaa cggatattcc tatccttcat atgccaagag aagcagcaaa
    28621 tgaacttgtc cgtcagcata cgacagggag agtagcgatt ctaggaacag aaggaagtat
    28681 gaaagctgga atctatgaac gcgaagtcaa aaatcttgga ttcgaaacag tgattcctga
    28741 tactgttctt caagaaaaaa tcaattatct gatctatcat gagatcaagg aatcggatta
    28801 tttgaatcaa gagctatatt acgaaatctt agaagaagcg gtagagcgcc taaactgtga
    28861 aaaagttatc ttaggttgca cagaattgtc attgatgcat gaatttgctg aagataacca
    28921 ttatccagtg atcgatgccc aatctatttt agcagatcgg acgattgaac gagcgctagc
    28981 tgaaagaagc aaggcattgg atacagcatc ggaaaagtaa aaaaattgga tttggggcaa
    29041 atatcctaaa agatatttgg tccaaatctt tttgtaaaag aaaaagaaaa ctggtaatga
    29101 tacgcccgga atgatataat tttactatgc acaatgtgag aggagttcgt aattatgaca
    29161 gataatttgc aattagtcat cataacaggt atgagcggtg cagggaaaac agtagctatc
    29221 caaagttttg aagatatggg ctatttttgt atcgataata tgccgcctcg attgattcca
    29281 aaattctggg aattaatcaa agaatcaggc aaagtcacaa aaatggcttt aggagtggat
    29341 ttacgttctc gttccttctt tgaagaaatc caaaacatgc tgatcgaaat cgaaaatacg
    29401 aacttcatcg acacttctat cttattttta gatgcttcag acgaagaact agtggctcgc
    29461 tacaaagaaa caagacgagc acatccaatg gcgatggacg gtttgatcac tgaagggata
    29521 cgtaaagaac gggcgatact agacgacttg aaagcccaag cttccgtgat cattgatacg
    29581 acgacattga caccacgaca attacgtgaa aaaatcaatg agtcattcaa atcaaaggga
    29641 gaccaaggat ttcggatcga atttgtatca tttggtttta aatacgggtt gccgatcgat
    29701 tcggatattg tgatggatgt gcgttttttg cccaaccctc attatatccc ggaactaaga
    29761 ccattgaccg gaaaagatca gccagtctat gattatgtga tgtcctttga tgaaacgcaa
    29821 tcattctacc ataaattttt ggatcttctg gaaactgtat tgcctggata cattaaagaa
    29881 ggaaaaagca gcttgacagt tgcaatcggc tgtacaggcg gtcaacaccg ttctgtggca
    29941 ttgactgaac gtttggcaaa tgctttaggg aaaaactata aagtcaatgt gacacatcgg
    30001 gacaaggata aaaggaaaga gacggtgaac cggtcgtgaa aatgaaaacc taccggataa
    30061 gaaaaccaaa gatcgtagtg gtcggcggtg gcactggtct gccagttatc ctgaaaagtt
    30121 tgcgaaatca aggagcagat atcacagcag tagtgactgt tgcagatgat gggggaagca
    30181 gcggtgcaat cagagaatcg atcgctatgg ctcctcctgg tgacttgaga aatgtcttag
    30241 tggcgttatc ggatatgcca caattctatg aagatatttt ccaataccgt ttcaaaaagg
    30301 aagatcagtt tttagccaat catacgatcg gtaatctgat cattgccgca gtttccgaga
    30361 tgcggggaag cacttatgag gcgattcaat tattagcaaa aatgatgcat gtagatggac
    30421 atgtttatcc ttcttcagaa actcctttga ccttgcatgc tgtctttaaa gacggaacga
    30481 ctgcagtagg agaatctaaa atcgcgatcg accgtaaaac cattgaccgt gtgtatgtct
    30541 gcaacacaaa tgataaaagt gaagccaaag cggctcgaaa agtcgtttca gcaattatgg
    30601 acgccgacat ggtcgttttg ggacccggaa gtttattcac cagtatcctt ccaaatttag
    30661 tgataccaga aatcggcgaa gcaatgctca agacaactgc tgaaaccgtc tatatctgta
    30721 atatcatgac ccaaaaaggg gaaacggaac atttcacaga tgccgatcat atacgtgttt
    30781 tacacaagca tttgaatcag ccttttatcg atacagtatt ggtcaatacg gaaaaagtgc
    30841 ctgaagatta tatggaccca gagatctatg atgagtatct agtacaagtc gcacacgact
    30901 tcaacggatt gagaaatgaa ggatgtcgag tgatttccac cgactttttg gaattgaaag
    30961 atggtggtgt cttccacgat ggagacaaag tagtagaaga attgttccgt ttagttttcg
    31021 gttcaaaata ttaagcaatt tattgttgga gaaaggagga gaataggatg tcatttgctg
    31081 cagatgtgaa gaaagaacta actggtttgg aagttcatcg agaacatgcg aaagcggaat
    31141 tagctgcttt gctgcgaatg aacggctctt taggtattgt gaaccagcag tttattttga
    31201 acgtccaaac agaaaatgct gcaattgcca gacgtatcta ttctcttttg aaagatcatt
    31261 atcaggtacg aagtgagcta ctcgttcgta aaaaaatgaa attaaaaaag aacaatgtct
    31321 atatcgtccg gttgaagcaa ggcacaaaag atgtgttgat ggatcttgat atcatggatg
    31381 gtatgatgtt caatggacac gtttcggacg agattatggg aaattcgcaa aaaatgcgtt
    31441 cttacttacg tggtgctttt atggcctcag gttcagtcaa taatccggaa acgagccgtt
    31501 atcatttgga aatattttct atttatgaac agcataacca agacatttgc gatatgttaa
    31561 attattacgg tctacatgct cgaacgcttg aacggcgcaa tggctatatt tcttatttaa
    31621 aaggagcaga aaaaattgct gatttcttaa cattgattgg tgcaaccaac tcaatgctcc
    31681 gatttgaaga tgttcgaatc gtacgggata tgagaaattc ggtcaatcgt ctagtcaatt
    31741 gtgagacagc aaatctgaac aagacgattg atgcggcttc taaacaaatc gaaaacatcg
    31801 aattgatcga agcaaaggtc ggtctacatg cccttcctga aaaacttcag gaaatcgcag
    31861 aacttcggct tcaacatcca gaggtcagct tgaaagaatt aggggaaatg attccctcag
    31921 gtgcgatatc aaaatcggga attaatcacc gaattcgcaa aataaatgaa tttgcggaaa
    31981 aactgcgtga agaagcagtt taatccaaag aaaaaactga tacatgaagc aggagatgcg
    32041 aatgtatcag ttttttttaa aagttatact tgcttttctt ccgtcaaact ataattccat
    32101 ctttactgga gtaacataat ttggaaaggc ttctattgtt tttaatacaa tcgtataaaa
    32161 agcggggaga caactgaatg aagattttag ttttgtacat aaatttttgc ttaatataga
    32221 agtcctgata tagataagat caagtattta tctataactg gcctgattaa ttaaaaaact
    32281 ggaaggaact gctcgatcat ccttgagaac tgctcttctt acttctggtc aagattctcg
    32341 tggttggtgg ataaggatgg ttgataagtt cattggatta gctagtcgaa aacaaccagg
    32401 tgtaattaat gtagaagttt taacaagggg atggagtgat ttattcagtg ataatcataa
    32461 gttcataaat agtaattgag atgtatggtt ggaatacgtt atacctgaac ttgaactacc
    32521 aagatttggt ttagaatttg agaatcgatg tttataaagg gagggcaaaa atgcgttttt
    32581 ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat atagcaaagc
    32641 gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata acatttatat
    32701 cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact ccagcaccac
    32761 cattgccaga gattacatat ggagaatttc cttttagact tgagtatgaa ttgaatgaag
    32821 aattacatgt gatagaagac acgttaatag ttgaatttga tggatttgga atgaacgaag
    32881 gcatagggag atatcgtaga tggacaagtc gtttagccag cggagaagat ttagtgttgc
    32941 tgttagaagt tagtgataat aagcaaatat tttattttcc aggacctgct aattattaca
    33001 tgggagatag gttgaatggt tataatcata cttttcctag tgcttctttc attgaaaggg
    33061 aaagaggcat tactagaagg gatattttac atgacaaaga attattagaa caatttggtc
    33121 cgcttgatca aaatacaata aatgaagaag aattgttaaa tcaatataat ataaggctag
    33181 tgaattggga aatatctgaa ccgattgtta acaattttgg tgattagaaa acaattacga
    33241 taaatagaaa caagccaaat catcagcaag taaaagctga tgatttggcc tttcttatac
    33301 gagtagtagg aattcatagc gaatattatt acgatcagta gatattttga tattaaagga
    33361 gtattacgaa ctagtatgtg agaatgtaga ggtgatttgc gaataatgag aaatttatca
    33421 aatagaaaca aaatattaat cattattgtt gttatagctg tgtttcatct gggaacgaat
    33481 gcggttttaa gtagaataat attgggtcct aagccaccaa gacctgcgat tacccgaggg
    33541 gagtttgatt ttagattaga atatgaagta gatggggaaa ggattgtgat agaagataca
    33601 attgttgcat tatttgatgg attttctgca gatgcaggta gcatggcatg gtatcgcacg
    33661 tggcgtttgc atttggcgag tgacaagagg gcacaacaat tattgttaca tgagttagat
    33721 gatggtcgaa aaatatatta tcattttgga ggagctggat tttatatggg gaagttagta
    33781 gcagtgtaac tgtaacaagg aaagatttgc caggtcttgg cattcgaaac tccatatttt
    33841 atatcgagcg tgggagagat acatctattg ggaacaggaa agggttaact cttgaagagt
    33901 tatataatga ctttggaatc cgtcttgtta gttgggaaca caatccacca atagaaaatc
    33961 gctttgaata atcgaaatct attaatccat ttcatcagcc agtgaatgtt gtaatggaac
    34021 aatttggttt agtgttcaaa accattgaaa tactaggctg tgatcagcaa aaatgtatct
    34081 gaataaaaaa gagagcaact attaaatgag aggagttagg agttgttagc tttatacgaa
    34141 tcaaagtggc aaatacagat gcgtatgcat ttgtgtttgc catcttgcgt ttggtagacg
    34201 agataggtat aagctaaaga aacaacttgt ttaaaataaa cgacctagct caacaaacga
    34261 ccatctaatc aactaacagc atacataaaa gcaactattt ttgaagtaga attgaaatcg
    34321 ggataactta aaaagtgatt gggatactag tgtgaatcac cgtacataaa tattactcgt
    34381 taagggaatt tgagaaattt tgtatgaaaa tttaagaatt agttagtatg cgcaagtcaa
    34441 aaatatgaat aaattatttg gtggagataa tttgctcagc ttgtcataag aaatgagata
    34501 atctggcaga tgcaagcttt tggacaccat ttattcggaa taaggaggct gggacagaag
    34561 cgtttaactc caagaaataa gaaggagttg cttctgcttc cgccgtttat aggtgtttag
    34621 agcgtgagac aaaagtgttc tttacttttg tcctacgctc cttatttttt tattttgttt
    34681 ggatcaattc ttttaattcc tctattgaaa tagattcatc aaagatttct ttacccaaga
    34741 tgacagtcgg aacaaatcga atatgtgctt gctcagcttc gttgatgaca gcttggctca
    34801 gctgttcgtc tttttgttct gtcagcttta gtttatctac tgcaaaatcc gctacttctt
    34861 ggagagaaag atgtttccac tcgtcttgag tatcgaatat ttgtttgatc tctttgatcg
    34921 ctttttgacc atcgctgatt gtgagatacc ggtgcatcac gtttcctcgc tgcaagcttt
    34981 ctttttcttt atcgaacaat ttgatcactc gctgcaattg cccgctttgg actgcttctt
    35041 ctaatagctc ataagattct tcaaaccatt gtcggcaata cggacaagat aggttgatga
    35101 attcgaccat ttttttagga gcattcgatg aaccataaag gattcctttt tgtgtatttg
    35161 ttttcgttgc atcaatcact gatatatcca tgttaaaaca cctctttcgc ttatagttta
    35221 tacatgtctg acaaaaaaag gcaacgattt agactgtttg tctaaaaatt agatgaccaa
    35281 ttcaaataga catatgtgaa atatttttat aaataaaaga aaaaatggaa tgttttacgt
    35341 tataatggaa cagataataa gagagaatat gaacaaggat gatgaatcat gcgaaaaatg
    35401 aaaacaatgg atggcaatac ggcagccgca tatatttctt atgcatttac cgagattgct
    35461 gcaatatatc caataacacc cagttcgacc atggctgaat tagtagatca atggtcagca
    35521 gcaggaaaag aaaatgtatt cggtcaacca gtaaaagtag tagaaatgca atccgaagca
    35581 ggagcagctg gtgtggtcca tggatcattg aaaactggtg cactgacaac tacatatacc
    35641 gcttctcaag ggctgctttt gatgataccg aatatgtaca agattgctgg ggaactactg
    35701 ccaagtgttt tccatgttgc tagtcgggca gtgacgacaa atgcgttgaa tattttcgga
    35761 gatcacggag acgtgatggc tgcaagacaa acaggatttg ctatgttagc tgaaagcagt
    35821 gtacaagaag tgatggattt agcacctgtt gcccatcttg cttctattga aggagaagta
    35881 ccttttttga atttctttga tggattccgt acgagtcacg agattcaaaa aatcgaagtt
    35941 ttggaatatg aagaattagc tcctctgatc aatcaggaga aattagcttc atttcgtaaa
    36001 cgagggatga atcccaatca tccgactgtt agtggtacga accagaatcc agacatccat
    36061 tttcaacaac gggaaacgat caacccctat tatgataaat tacctgaaat cgttcaaaaa
    36121 tatatgaaag agatcaaccg attacgagga acttcttatg acttggtgac ttattacgga
    36181 gcagacgatg cggaagaagt cattgtttct atgggatcag ttgcacagac gattgaacaa
    36241 acgattgatt acttgaatgc aaacggacgg aaaacaggtt ttttgaatat ccatctttat
    36301 cgtccttttc cagtggaaac attcgtgcaa aagttgcctc atacagtaaa aacaattgct
    36361 gttcttgatc gaagtaaaga accaggggca ggtggagaac ctctcttatt agacgttcaa
    36421 agtgcgttat atgattctga acttcgcccg gctgttattg gtggtcgcta cggattgggg
    36481 tctaaagatg tgactcccga ccaaatctca gcagtttttg atgaattgaa aaaagaccca
    36541 agcatacgca aaaaacggtt taccataggg atcgtggatg atgtgactta tcaatctttg
    36601 gaaccaaagg aaagtctgga tttgacagaa ccgcaaacat tccaggccaa gttttgggga
    36661 tttggatctg acggaacagt tggagcaaat aaatcagcta tcaagattat tggagatcac
    36721 accgataaat atgcgcaagg ctatttttat tatgattcga aaaaatctgg cggtctgact
    36781 gtctctcatc ttcgttttgg agatacgccg atacgttcag cgtatcttgt cgagcatgcg
    36841 gaccttgttg cctgtcacac accagcttac ctgcatagct atgacttggt caaaggattg
    36901 aagccaggtg gcattttttt attgaatact ctttggagcg acgaacaatt agaaacgcat
    36961 ctgcccttaa aattaaaacg ttacttggct gaaaataaca ttagattcta tacgatcaat
    37021 gccatgagat tggcccaaga agtcggtttg ggacgccgga tcaatacggc aatggaaacg
    37081 gcttttttta aattagctga catcattcct tttgatgagg tgcttccgct gctaaaagaa
    37141 gaagccctga aaagctatgg acataaatca atggctatcg tagaaaaaaa catacaagca
    37201 atcgatcgga cgaccgaact gcttcatcaa gtcgcgatcc cagaccattg gagaacgttg
    37261 gagatgcctg aaaaaatcaa taaaaggaac actggttata tacaagaaat acttgaacca
    37321 gtgaatgcac aggaaggaaa tcaactctct gttggtacac ttgtagcaaa tggaatgaca
    37381 actggcgaaa tgcctttagg aacggcttct atggaaaagc ggggcgtcgc tttagaagta
    37441 cctgagtgga ttagtgatcg ctgtacgatg tgtaatgaat gtgcctttgt ttgtcctcat
    37501 gctgccatcc gtccattttt agcagatgaa gaggaaatgg aagaagcgcc agaaggattt
    37561 atcgtgagag aaatgcgagg cgcagacggc gtaaaatacc gtatccaagt ttcagtggaa
    37621 gactgtacag gttgtggtct gtgtgtagag gcttgtcccg caaaagaaaa agctttagtg
    37681 atgaagcctt atgaagaaca gaaagaacaa gctgtgaatt gggcttttgc aatgacatta
    37741 agacaaaaag caaatccagt caaaggaaag aatactgtct tgtctacaca attcaatcaa
    37801 ccgcttcttg aattctcggg cgcttgctca ggctgtggcg aaacacctta tgtaaaatta
    37861 ttgacacaaa tgttcggtga tcgaatgatg atcgcgaatg cgacaggctg ttcttctatt
    37921 tggggcggtg cttctcctgc ttctccttat acgaccaatg aatgtggtca agggcctgca
    37981 tggtcaaatt ctttattgga agataatgct gaatttggtt atggtatgct tctagcggca
    38041 cagactcgtc gcgaggcttt ggcaagttca atcaaagaag tattgccaaa agtatcagaa
    38101 gaactacgag aattgatgga agactggttg gtacacatgt ttgagagcga aggaacgcag
    38161 caaagagcag caaaactgca agctgcgatc gaaagcgaac gatcaattgt ccctgaactg
    38221 gaggatatat acaagagaaa ggatctattc gtaaaaaaca gccaatggat gattggtgga
    38281 gacggatggg cttacgacat tggttttggc gggatcgatc atgtacttgc cagcggagca
    38341 gacgtgaata ttcttgtttt ggataacgaa gtctattcca atactggcgg tcaaacctca
    38401 aaagcaacac cagcttcggc aatcgctaaa ttttcggcta gtggaaagta tgcttcaaag
    38461 aaagatctag gaatgatggc gatgacatat ggaaatgttt atgtggcgca aattgcttca
    38521 ggtgccaatc aaatgcagac gataaaggct tttgaagaag cagaaaagta tcctggacct
    38581 tctttaatca ttgcctatac gccttgtatc acacatggtt tgcttggtgg aatgaaagaa
    38641 tcgcttaaag aagcaaaaga agctgtttct tctggctatt ggtcattata tcgatataac
    38701 cctgcaatgg tcgaaaaaaa caagaaccca atgactttgg actacaaaaa acctgatttc
    38761 tctgctatgc ctgatttcat gaggaaacaa gttcgctttt cctcgctaga gaacgcaaat
    38821 ccaaatcttg caaaagcttt atttgaaaag actatccaag acgctaaaac acgtttttac
    38881 aactatgctg cactgacggg agaattagaa aaaatcaaga aacgacttga accagaggaa
    38941 tctatcgatg tacccgttaa gactagaaaa gaaaaaacga cggaccttga agcagaagaa
    39001 agaagagctg ccagagcaga acgacgtaaa aaaatggaac aagctacaaa agaaaaaaag
    39061 gaaaaataac agaaaaaata taatgaataa ttctctgaag tttaaaaata tttattgcag
    39121 agaaaaataa aacgcatact tgcaattttc ctgaaaatta tgcgtttttc tcaagaaaaa
    39181 tacgagcaga tcagcctcta aaattaaaac atatgatata ctagagagga aatctcaaaa
    39241 gagaagagag gctttttatg tcatttcaaa tcggggaact ttttaatttg gactattggc
    39301 agcaaatgtt ttccggtgac ttgttctctc tgaatttttt ggtgaacata cttgatattc
    39361 tggttgtctg gtatcttgta tacaaactga tccaactgct gcgaggcaca aaagcgattc
    39421 agcttctgaa aggtgtagct atttttattg ttatccgaat cgtagcggaa atcattggtc
    39481 tgcacacctt gtcttggctg atgaaccaag tcattacgta cggggtgata gctgctatcg
    39541 tgatttttca gccggaaatc cggagaggac tggaacatct tggacgcagt tcgcttttca
    39601 aacaatcaaa aagcgaacag caggaagatg agaagatgat cttgtctttt gacaaagcca
    39661 tccaatatat gtccaagcga aaaatcggtg cgctaattac tatcgaacgg catactggat
    39721 tagatgagta tattgagaca ggaattgcat tagatgcaga tatcactgga gagctgctga
    39781 tcaatatctt tattcctaat acaccgctgc atgacggtgc agttattgta aaagaaggaa
    39841 agatcgcagt agcaagcgcc tatcttcctc tatcagaaag tatgttgatt ccaaaagaat
    39901 tcgggactcg acaccgggca gctgtcggta taagcgaagt cagcgacgcg attaccatcg
    39961 ttgtctctga agaaactggg gatgtcagca ttacattaga taatgaactg atggctggct
    40021 tatcccagca agaatatttg gcaattttgc gtagagaact gattgctgaa gagaaaacaa
    40081 aaaacaagaa aaacgtgatt caatctttcc tagacggtat gactaaggga ggggatcgca
    40141 aatgatctca aaagagaaac ggacaagcat tctttacagt tttattgcat tgctgttcag
    40201 tattgcgctg tacttcaatg caaatggcca gtccgttcca aatacgcttt ctggaaatga
    40261 agcgtataat caaacagtta ctggggtgcc aatcaagatt tcttatgatt caaagcgcta
    40321 ctatatccat ggatatgaaa atgcagtgac tgtcaaactt tccagtgcaa accgagttca
    40381 gttgaatgca gaggcaaacg aagatacacg gatgttccgc gtcacagcag atatcactaa
    40441 gctgggcgaa ggaacacatg aggttccgct aaaaattcaa aatttgagca gtgctgtcac
    40501 agcaaagatc gaaccatcga ctattacagt aacggttgag aaaaaggtaa taaaagattt
    40561 cgatgtggaa acgttgattc cttcaacgtt cacaccatct ggatatgaac ttgatgatac
    40621 ttccgttagt cctaaaaaag tctctatcac tacaggtgac aaaacattgg cagaaatcaa
    40681 acgagtagta gctgatgtgg acgcttcgat ggtcacagat gatgggatta atagtgaggt
    40741 cccaatacag gcgctgaatg cagcagggga agtattaagt atcgtctctg atccagtgca
    40801 agtaacagtg agagctgatt cgatcaagcc aagcaagtcg gtacgacttt atgggataca
    40861 gcaaggaaca ccagctgccg gggtagaaag ctatgatttc agtttttcaa aactggaagc
    40921 agaagtaagc ggctctagcg atttgcttgc atcgatcggt gacagtattg ctgtaccgat
    40981 caatgtctca ggtatcaatc atcgaacaac tcgtaaaatt gaaataccag tagaagaggg
    41041 gttaagtatc aagcccgaat cagttagtgt ggagattaca cccgtgttgc aaacgtcaag
    41101 cagtagctct gcttcgacga gcagtcggac acaagaaaat acaagtacga gtagaagtat
    41161 ttcatctgct gattcaggaa cggaaccatc gacaacaacc atttcttcca gttcggaatc
    41221 tgggacaagc agctcgacca caagtacaga agaaacatca gaaacaagcg aatcaacaca
    41281 aatgagcaga acaaattcct cagaaaatta agttaaagga gtaattttac aactatgggt
    41341 aaatattttg gaacagacgg cgtacgcggt gaagccaaca aggaacttac gccagaactt
    41401 gcatttaagc tgggacggtg cggaggttat gtcctaagcc agcatgaaga agaaggaaaa
    41461 cgcccacgcg tgttagtagg gcgggataca agaatctcag gtcaaatgtt agaagaagcg
    41521 ctgatttcag gacttttatc ggtgggtatc gaagtgttcc agctaggtgt gatctctaca
    41581 ccaggtgttg cttatctgac acgtttgcaa aaagcaagcg caggggtcat gatttctgct
    41641 tctcataatc cagcacaaga taatggaatc aaatttttcg gtgcagatgg ttttaaacta
    41701 gtagatgacc aagagctaga aattgaagca ttattagatg ctgaagtgga tgaattgcct
    41761 cgtccatcag ctgaaggatt gggaactgta gaagaatttc cagaaggctt attgaaatat
    41821 tctcaattcc ttgtacaaac gatcaacggt gacctttccg gtttgaccat ttgtgtcgat
    41881 gcagcaaacg gagcaacttc aacaagtgtt aatcgtttgt ttgccgatct tgaaacagat
    41941 ttttatacca tgggcacaaa tccagacggg ttaaatatca atgatggcgt aggctctacc
    42001 catccagaac gtttagctga gatggtcgtt gaaaaaggag cagatgctgg actagctttc
    42061 gatggcgatg gcgatcgtat tattgcggtg gatgaacttg gaaacattgt cgacggtgat
    42121 aaaatcatgt ttatctgtgc taaatacttg gcagaaaaaa atcgattgaa aaaagatacg
    42181 atcgttacga ctgtcatgag taacttagga ttccacaaag cggtggaagg aatcggtttg
    42241 aaagatgtcg ttacacaagt tggtgatcgt tacgttgtag aagaaatgcg caaaaacgat
    42301 tataactttg gcggcgagca gtctgggcac atgattttct tagattttaa cacaactgga
    42361 gatgggatgc tttcaggaat tcagttactg aatatcatga aacagacagg taagaaatta
    42421 tcagagcttg cagcagaggt aacaatctat ccgcaaaaat tagtgaatat ccgagtaagt
    42481 gataaaaacg gtgcgatgga tgttccggca atcaaaaaag tgattgaaga ggcagaagct
    42541 gaaatgggat cagaaggaag aatcctagtt cgtccttccg gtacagaacc attacttcga
    42601 gtgatggcag aagcgcctac tgatgagaaa gttaattact atgtcgataa aatcgcggca
    42661 gtagtcaaag aagaaatcgg actggattaa gagat
//
LOCUS       DASHXG010000022        38599 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.022, whole genome shotgun sequence.
ACCESSION   DASHXG010000022 DASHXG010000000
VERSION     DASHXG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.022"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(98..1228)
                     /locus_tag="U2R59_001308"
     CDS             complement(98..1228)
                     /locus_tag="U2R59_001308"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEM8965711.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="U2R59_001309"
                     /pseudo
     CDS             complement(1877..3079)
                     /locus_tag="U2R59_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(3139..3342)
                     /locus_tag="U2R59_001310"
     CDS             complement(3139..3342)
                     /locus_tag="U2R59_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEM8965712.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="U2R59_001311"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="U2R59_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="U2R59_001312"
     CDS             4879..5691
                     /locus_tag="U2R59_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965713.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="U2R59_001313"
     CDS             complement(6715..6867)
                     /locus_tag="U2R59_001313"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEM8965714.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="U2R59_001314"
     CDS             complement(7058..7936)
                     /locus_tag="U2R59_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8965715.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="U2R59_001315"
     CDS             complement(7975..9093)
                     /locus_tag="U2R59_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HEM8965716.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="U2R59_001316"
     CDS             complement(9090..11189)
                     /locus_tag="U2R59_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HEM8965717.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="U2R59_001317"
     CDS             complement(11240..12061)
                     /locus_tag="U2R59_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8965718.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVMGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="U2R59_001318"
     CDS             complement(12058..12867)
                     /locus_tag="U2R59_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8965719.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="U2R59_001319"
     CDS             complement(12888..13382)
                     /locus_tag="U2R59_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8965720.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="U2R59_001320"
     CDS             complement(13394..13882)
                     /locus_tag="U2R59_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8965721.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="U2R59_001321"
     CDS             complement(13959..16655)
                     /locus_tag="U2R59_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8965722.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="U2R59_001322"
     CDS             complement(17083..18156)
                     /locus_tag="U2R59_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965723.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="U2R59_001323"
     CDS             complement(18153..18980)
                     /locus_tag="U2R59_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965724.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="U2R59_001324"
     CDS             complement(18981..19787)
                     /locus_tag="U2R59_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965725.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="U2R59_001325"
     CDS             complement(19799..20884)
                     /locus_tag="U2R59_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965726.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="U2R59_001326"
     CDS             complement(20901..21443)
                     /locus_tag="U2R59_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965727.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="U2R59_001327"
     CDS             21701..22690
                     /locus_tag="U2R59_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HEM8965728.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="U2R59_001328"
     CDS             22687..23424
                     /locus_tag="U2R59_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEM8965729.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="U2R59_001329"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="U2R59_001329"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEM8965730.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="U2R59_001330"
     CDS             23988..24620
                     /locus_tag="U2R59_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8965731.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="U2R59_001331"
     CDS             24705..25352
                     /locus_tag="U2R59_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8965732.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="U2R59_001332"
     CDS             25357..26340
                     /locus_tag="U2R59_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HEM8965733.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="U2R59_001333"
     CDS             complement(26743..28257)
                     /locus_tag="U2R59_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HEM8965734.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="U2R59_001334"
     CDS             28395..29201
                     /locus_tag="U2R59_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965735.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="U2R59_001335"
     CDS             complement(29376..29945)
                     /locus_tag="U2R59_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8965736.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="U2R59_001336"
     CDS             complement(30028..32088)
                     /locus_tag="U2R59_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEM8965737.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32365..33843)
                     /locus_tag="U2R59_001337"
     CDS             complement(32365..33843)
                     /locus_tag="U2R59_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965738.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34141..35076)
                     /gene="murB"
                     /locus_tag="U2R59_001338"
     CDS             complement(34141..35076)
                     /gene="murB"
                     /locus_tag="U2R59_001338"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEM8965739.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35149..36069)
                     /locus_tag="U2R59_001339"
     CDS             complement(35149..36069)
                     /locus_tag="U2R59_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEM8965740.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36182..36934
                     /gene="xth"
                     /locus_tag="U2R59_001340"
     CDS             36182..36934
                     /gene="xth"
                     /locus_tag="U2R59_001340"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEM8965741.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37798..38331
                     /locus_tag="U2R59_001341"
     CDS             37798..38331
                     /locus_tag="U2R59_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HEM8965742.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT        11574 a         7959 c         6543 g        12523 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga actatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccatgacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaaatcgga ataataactt atgtactttt taattttgtt aagtaatata tctagttata
    32281 tctagttata tctagttacc ttttctttga aaaaaacata aatcagctaa taaatatgtg
    32341 agacaaagct gccatccata aatactagct gattttttca gttaaatgtc tatttttttc
    32401 tctgatgatg gtatttccaa aatattccca gtcatctgga gtcggtggat ttttccaaat
    32461 tatctgttct ttattaaatt tttcaagtaa acaatcagat aaataaatat tcgtacgaga
    32521 agtgattcga ctctcaatca caatattgta atttttaaat cctttcactt gagaaataat
    32581 gtaatcggta taagcagatc cttgcgaaaa atcaatacag acatgaatcg gtgcttcaaa
    32641 atatgatacc ggacaaatac cgaccaataa aaagagataa tcataaaata agcgaatcat
    32701 gaaacgttca tcttttccca agaaatagcg tttattctct tgtatgacct tttggattgc
    32761 tgtactgaat attggatacg tctcgaagaa aaactgtagc tgctttttag acgtaaagct
    32821 agtcatctca aagtcgaata tccaattttt tcgattgaca tgcatcatac ccatacgaag
    32881 ttcttttcgt atatatagtc tttcttcttc agagatttca atcgaaaatg gtaattgatc
    32941 aatcaattcc actgacattt tttgactaat catgtggata tcatgaaaat gagcttccgc
    33001 aagtccaaat gcgccatcta attcaaattc ttcttccgtg atcaaaaaca acatgatata
    33061 agaaatctca tcaatgatct gctctttagg gatatgaaga aaagaaatat gtgataaatc
    33121 cttgatgatc ttcattcctt ctgagctctt aaagtattca tctgaaaaga aacgttttcc
    33181 gattggttga ttcccatagg ccctcaacaa actaatagtg gttagcaaat tgaatttgat
    33241 tcgttttgtt gcagacagtt ttaaattgaa cagatattca aaatattgca cgatactctt
    33301 tgcttcattc atgacgcttt ctctaaatgg catagaaaaa ccattaaaga ccccgaaata
    33361 taccccaaat aatacgttcc gtatgtttat ttcttcccca actaatatgt ttttctttaa
    33421 ctttatttga tgctgttcaa gaaaagagac taattctctt ctttttacat aggctcttga
    33481 tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt acttttgaat ccacgatctc
    33541 cgttaacagt cgagcaattt ttgatcgttg aaagtagatt cttcttaaat ttttgatatc
    33601 cgtcaaattc agacgttcga catggatctc tgcttcttct gaaatttgga tctctggctt
    33661 tgttttgaat tcagtaaatt ctttatttaa ttctatgata taatttcttg ttttaaattt
    33721 agacaaacct aatgtttcat ataacttagg cagcactaca taattctttt tctcaaattc
    33781 taaatatcta gctagcagca gtttttctct atcttcctct tctataaggt aatccaactt
    33841 catatcctac acctcaaaaa atgcctcata ccaattactt gatatgcaga tgaaagttca
    33901 tcttttcacc tatactgatt ttatgatgga ttatgcttgt tttttcatca gttattctca
    33961 ttttttatct tttttttgag aatattgcaa aaaatggaaa aatttatgag gaaatattct
    34021 atattttttg ttttattgtg ttaaaatgta caagatttgc gccatttgcg taaacaacca
    34081 caaaaaagag caggacggcc accgtcctgc tcttttactt attttaagtt ccattactta
    34141 ttaattggct aaacttctgc ttgtttctga tattgcttgt ttttctccaa tgatccgcac
    34201 ttctgtttct aaagacacat caaatttttc tttgattact tcttggatgt gcgcaatcaa
    34261 ttcaatataa tctgtcgctg tcgcatgatc gatattgacg atgaatccag catgtttttc
    34321 agagacttgt gcaccgcccc atttcaggcc ttgcaatcct gcttgttgga tcagctgacc
    34381 tgtatagtgt cctactgggc gcttaaagac acttccgcat gaagggtatt ctaatggctg
    34441 ttttgattga cgcaattcgg tcaactcatc cattcttgct ttgattgctt cataatcccc
    34501 tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt aattcttgga ctttactgtg
    34561 acgataagaa aataccattt cgtcttttgt caaagttttc aatgttccat cttcaagcaa
    34621 aagatccact tcagcaaaaa catctttgat ctctccgcca tacgcacctg cattcatata
    34681 aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat tcaaatccag tcaatgattc
    34741 tgccaaagct gcataagtcg tatcaatcag tgaggcacct gcttccgcaa tgaccatcgt
    34801 tcctttgaca tgaatctgtt tcatttcagt cagcatgatg actacaccgc gaatcccgcc
    34861 atcttgaacg atcagattgc ttgcatttcc taataccatc caaggtatat catggattcg
    34921 gcaataatcg atgatttgct ttacttcttc ttgttttttc gggaatgcaa ggacatcagc
    34981 tggtccacct gttttcgtaa acgtatagtt catcaatggt tcatcaaaca atatagtaat
    35041 cgtggctaag ctttcaacta tttcttcttt attcactgag gattttcctt tcttttctca
    35101 aacgtcctca ttattctatc acgcttaata caatcttgcc agtcttgttc aaagttgatg
    35161 acggtagtga tctttaagca cttcctcaca taattcatga cttcttacaa cttctttttg
    35221 tttaagcaat tctgtttccg atttacctaa acggatctga gaaaagaagg cctctaccat
    35281 tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg ccaaattctt tcactttttt
    35341 tccatcagca tcttgaatga caagctgggt cagatcgttt acttcataag taccattttt
    35401 acttgttact tgatattttt ctatattagc gccacttgct aaatccatcg ttaaaatagc
    35461 cgtttgattt tgtgtttcta attgtaaaat ggcatattcc aaaaattcct ttgtttctct
    35521 tatctggtat tttgttctca aaatgggttc atctaataaa tacacagctg tatcaataag
    35581 atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct tttgccgcta ttcgattttt
    35641 ttgcaggtgg atcaaccgct tatctgggat acgtttcaat tcttctacca taggagcaaa
    35701 gcgccggttg aaaccgatca tcaaaattat ttggttctta tcagctaatt cttgcaattc
    35761 acgaacttca tttagatgga cactcagtgg tttgtcaata taaacatgga taccattttc
    35821 tagacatttt ttggctaatt cataatgtac ttttgttgct gcgtggatca tacatgcttc
    35881 gattttttct tctaaaagct catcgatcgt ttcatataga tgttggaacc cgtactcttt
    35941 ttgaattctt tcttttgttt ctttatttct tgttgcaaaa taaaaatcaa gtgttccttg
    36001 ttttttcgca taagttggta aatatgcttt ttctgcgata ttccctacac cgattacacc
    36061 aatcttcatc tactttcctc ctggatcatt tagttacttt catcttacac cattttttac
    36121 taaaatgagg tacaatagta tcgcaaaggt aaggaaatta attcgaagga gtgtgctttt
    36181 attgaaattt atctcttgga acgtaaacgg gcttcgtgcc atcgtaaata aaaatttttt
    36241 agaagttttt catgagttag acgccgattt tttctgtctg caggaaacga aactccaagc
    36301 aggacaaatt gatttagatc ttccaggtta ttatcaatat tggaattacg cggaacgaaa
    36361 aggctattcc ggcacagcga tttttgctaa aaaaccagca ttgaatgcca cttacggaat
    36421 gggtatcgat atccatgata cagaaggccg tctgattact ttggaatatt ccgatttctt
    36481 tcttgtaacc tgttacacgc caaattctca aagcgaatta aaacgtttag attaccgatt
    36541 agaatgggaa gaagcctttt ataattattt ggaaaatcta aaaaaacaaa aaccagtcat
    36601 cgtgtgtggg gatctaaatg tcgctcatca aaagattgat ttgaaaaact ggaaaacgaa
    36661 tcaaaaaaat gctggattca ctccagaaga aagagcggct ctttctcgac tgttggataa
    36721 cgggtttatc gatacattcc gttattttta tccaacccag gaaggtgtct actcttggtg
    36781 gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg cggatcgatt actttttgac
    36841 gagcaaagat ttagagccag gactagctga tgcaaagatc catacggaca ttatgggcag
    36901 tgatcattgt ccagtagaat tagatttgaa ataaagaggt tgtgaaaaag tcgtttagtt
    36961 tcgagtatta agaaaaattt tgtgaaaatg gctttccaca ttttgcataa atttggcata
    37021 ataccgagaa actggctttt gaacactgtt tatcgagaga ttgtgaaaaa gctgtcctgc
    37081 atcaagtaat aagaacagcc aaacaaaaat agttcctcat atttttcgtt tggttgggct
    37141 tattaccgca gatacaagct tttgaacacc gtttattaag aggttgtgaa aaagctgcac
    37201 tgcatcaagt aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg
    37261 gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg
    37321 cactgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt
    37381 tggacttatt accgcagatg caagcttttg aacaccgttt attgagaagt tgtgaaatca
    37441 gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata gttcctcata ttttgctatt
    37501 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa
    37561 agtcgcctac tttcgagtcg taagaaattt ttttgaaaat ggttcctcac aactttgcat
    37621 aaatttgact taataccgag aagtcatgat ccccatctaa ctccaaatca caaggaatga
    37681 gttcaaaaac tagcttttct caacaaatat tacataaaaa attctatgtt ttttgttaaa
    37741 tttatttgct tttttcaaaa gtatgttaca gtaatttccc aaggaggttt tacagaaatg
    37801 aattttgttg ccatggattt tgaaactgcc aatcatcagc cttatagtgc ttgttctctt
    37861 gcgctagtca tggtaaaaaa tagccagatc gttgatgaat tctatacatt gatacagcct
    37921 gagactcctt ttttctggcg aaatgtccaa attcacggaa tccatcaaga agacgtacgc
    37981 aatgcgccga aattcccaga agtctggcaa actatccaac catattttca aaaaaatcgt
    38041 ttagtcgttg cacataatgc tgcttttgat acaaaggtct tagcgggatg cttagattat
    38101 tatcatcttg aacagcctaa ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg
    38161 tttcctgaat ttccaaatca tcgattgaac actgtgtgcg aaaatttgaa catccaatta
    38221 gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa
    38281 gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga ctataaagta aaagaatact
    38341 tatgaaacac acaaagaggt cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt
    38401 tcaaaaaata gcttctcatg tttattaaat attgtgactg gtgaccgagg agctggcagg
    38461 agaacaccgt ttattggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    38521 ccaaacaaaa atagcttctc atatttttca tttggttgga cttattaccg cagatgcaag
    38581 cttttggaca ccgtttacc
//
LOCUS       DASHXG010000023        38075 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.023, whole genome shotgun sequence.
ACCESSION   DASHXG010000023 DASHXG010000000
VERSION     DASHXG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.023"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            214..498
                     /locus_tag="U2R59_001342"
     CDS             214..498
                     /locus_tag="U2R59_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HEM8965743.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="U2R59_001343"
     CDS             complement(779..1198)
                     /locus_tag="U2R59_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HEM8965744.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="U2R59_001344"
     CDS             complement(1200..1784)
                     /locus_tag="U2R59_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HEM8965745.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="U2R59_001345"
     CDS             complement(1831..3306)
                     /locus_tag="U2R59_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HEM8965746.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="U2R59_001346"
     CDS             3487..3798
                     /locus_tag="U2R59_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965747.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="U2R59_001347"
     CDS             complement(3913..6249)
                     /locus_tag="U2R59_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965748.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="U2R59_001348"
     CDS             6391..7059
                     /locus_tag="U2R59_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965749.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="U2R59_001349"
     CDS             7062..8105
                     /locus_tag="U2R59_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8965750.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="U2R59_001350"
     CDS             complement(8342..9223)
                     /locus_tag="U2R59_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8965751.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARNFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="U2R59_001351"
     CDS             9382..10110
                     /locus_tag="U2R59_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HEM8965752.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMALSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="U2R59_001352"
     CDS             10266..10583
                     /locus_tag="U2R59_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8965753.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="U2R59_001353"
     CDS             10576..11184
                     /locus_tag="U2R59_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEM8965754.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="U2R59_001354"
     CDS             11239..12030
                     /locus_tag="U2R59_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEM8965755.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12680
                     /locus_tag="U2R59_001355"
     CDS             12168..12680
                     /locus_tag="U2R59_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HEM8965756.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQARGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            12706..13578
                     /locus_tag="U2R59_001356"
     CDS             12706..13578
                     /locus_tag="U2R59_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEM8965757.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13754..14116
                     /locus_tag="U2R59_001357"
     CDS             13754..14116
                     /locus_tag="U2R59_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8965758.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14125..14877
                     /locus_tag="U2R59_001358"
     CDS             14125..14877
                     /locus_tag="U2R59_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965759.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14891..16693
                     /locus_tag="U2R59_001359"
     CDS             14891..16693
                     /locus_tag="U2R59_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965760.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIILGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16970..18010
                     /locus_tag="U2R59_001360"
     CDS             16970..18010
                     /locus_tag="U2R59_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8965761.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18062..20206)
                     /locus_tag="U2R59_001361"
     CDS             complement(18062..20206)
                     /locus_tag="U2R59_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEM8965762.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20563..21936)
                     /locus_tag="U2R59_001362"
     CDS             complement(20563..21936)
                     /locus_tag="U2R59_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8965763.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21936..22331)
                     /gene="rbsD"
                     /locus_tag="U2R59_001363"
     CDS             complement(21936..22331)
                     /gene="rbsD"
                     /locus_tag="U2R59_001363"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HEM8965764.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22359..23276)
                     /gene="rbsK"
                     /locus_tag="U2R59_001364"
     CDS             complement(22359..23276)
                     /gene="rbsK"
                     /locus_tag="U2R59_001364"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HEM8965765.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23384..24397)
                     /locus_tag="U2R59_001365"
     CDS             complement(23384..24397)
                     /locus_tag="U2R59_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEM8965766.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24478..25077)
                     /locus_tag="U2R59_001366"
     CDS             complement(24478..25077)
                     /locus_tag="U2R59_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8965767.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTIKKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25263..25964
                     /locus_tag="U2R59_001367"
     CDS             25263..25964
                     /locus_tag="U2R59_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965768.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25974..28685
                     /locus_tag="U2R59_001368"
     CDS             25974..28685
                     /locus_tag="U2R59_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965769.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLPQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29082..30710
                     /gene="treC"
                     /locus_tag="U2R59_001369"
     CDS             29082..30710
                     /gene="treC"
                     /locus_tag="U2R59_001369"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEM8965770.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGENMSEGNGWNALFFNNHDQPRALNRFVVIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30770..31951)
                     /locus_tag="U2R59_001370"
     CDS             complement(30770..31951)
                     /locus_tag="U2R59_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8965771.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32203..33726
                     /locus_tag="U2R59_001371"
     CDS             32203..33726
                     /locus_tag="U2R59_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEM8965772.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33795..34523)
                     /locus_tag="U2R59_001372"
     CDS             complement(33795..34523)
                     /locus_tag="U2R59_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8965773.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34536..35816)
                     /locus_tag="U2R59_001373"
     CDS             complement(34536..35816)
                     /locus_tag="U2R59_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8965774.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIDDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(35957..36559)
                     /locus_tag="U2R59_001374"
     CDS             complement(35957..36559)
                     /locus_tag="U2R59_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HEM8965775.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36804..37010
                     /locus_tag="U2R59_001375"
     CDS             36804..37010
                     /locus_tag="U2R59_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965776.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37322..38041
                     /locus_tag="U2R59_001376"
     CDS             37322..38041
                     /locus_tag="U2R59_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8965777.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTNK"
BASE COUNT        12176 a         6776 c         7669 g        11454 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcatcg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gtttttttgc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaattt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 cttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tctgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatggcact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aaggggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa attaaaaaag
    12661 taacattaga tatttattga aggataaagg agcgcaggaa gtagcatgag agaaaaaaga
    12721 gcattttata tcaatggtta tgcagggatt gtcggattgg tcgtattagc tttagttgga
    12781 ttgtttttct tctatttagg tatgtggcaa gcgaaagttt gggcactttt tttaagtatt
    12841 tttctttggt tgatcacgtt attgttgtta agttcggcaa ctgtagtcag tcctaatcaa
    12901 gcaaaagtaa ttttgttttt tggacaatat ttaggtacga ttcgagaaaa tggctttttc
    12961 cttacgatac ctttggcaca aaaaatgact gtttcgttga aagttcggaa tttcaatagt
    13021 tctgttttaa aagtcaatga tttggatgga aaccccatcg aaatctcagc agtagtagtc
    13081 tttaaagtcg ttgatacagc aaaggcatta ttcgatgtag cgtattatca agattttgta
    13141 gaaatccaaa gtgagacagc cattcggcat atcgctagcc aatacccgta tgatacattc
    13201 aatgagaatg atttgacgct tcgaggaaac acgacggcag tgtctgacga gttgcaaaaa
    13261 gagctgcaag agcgtttagc agtagcaggt gtcgaagtaa tcgaaacacg cttgaaccat
    13321 ttagcctatg caacagaaat cgctagtgcc atgctccaac gtcaacaagc aaaagccatt
    13381 ttgtctgctc gacaaaccat tgttgaagga gctgtcacaa tcactcaaat ggccttagag
    13441 caaatcgaag atggacaaga aatcaatttc accgatgatc ggaaagtcca attgatcaat
    13501 aatttacttg tctcaatcat tacagacaaa ggaacgcaac ctgttatcaa tacaggcgac
    13561 atgaaagacc gtaagtgaca tactttttgt aagataggaa gaaggagttt aggacggatt
    13621 attgtcttga actctttttt tagttgtttt aaagaaaatg acaaaattga aagaagaatg
    13681 atagttgatt cgaaggcaga attgttcgct tttttctata atcagtatat aaagtaagag
    13741 agaaggggaa aaagtgaaaa aacttctgat cggtctactt gttttcatcg ttgtggtact
    13801 tgcaggggtg aaaatcgcag attacgtagt tatgggtgga gaagaatact atgtacaaat
    13861 tacgacagat ggtacaaaaa cagtttcaaa atcagactct ggacaagaaa cagtcaacta
    13921 tagatatatc ctgcctggct atacgaaaga gggtaaggaa aaagaactgg acttcaaggg
    13981 acaattgact cgaccgcttc gtaaaggagc atatttaaaa atcacctgga acaaaaataa
    14041 aggtgtcact tcgtatgaag aagtcgaaaa aaaagacgtg ccgaaaacag cactggaaaa
    14101 actaattaaa gggtagggaa agaaatgaac aaaatagtcg aagtacagaa tgtaacaaaa
    14161 gtatacggaa aaaacaatga gaaaaagacg caagcattaa gcggcatcag cttcgatgta
    14221 gaaaaaggcg aatttattgg gatcatgggc gcttctggtt ctggtaagtc gacacttttg
    14281 aatattttat ccacattaga taaaccaaca gatgggcata tccgaatcaa tcaaaaagat
    14341 gtgaccacat taaaaggaaa tcaactagca gattttcgtg cgaatgagat tggctttatt
    14401 ttccaagatt tcaatttatt agaaagcttg acagcacaag aaaatatcgc tgttcctctt
    14461 tctttacaag gcgtcagacc aaaagaaatc aagcaacgtg tccaaaaaat tgcagaacgt
    14521 ttatccatct ctcatatttt ggaaagctat ccttctgaga tttccggtgg acaaaaacaa
    14581 cgggtcgccg ccgcacgtgc attgatcaca caaccaacga ttctattagg ggatgagcct
    14641 acaggtgcgc tggattccaa aagtgcccgg gatcttttag atacgatgga cgaattgaat
    14701 acaaaagatc atgtatcgat tcttcttgtg acgcatgatc cgttttctgc aagttattgc
    14761 caacgtattt tattcatcaa ggatggcggt atccatcaag aagtgaaacg tggagatcaa
    14821 agccgtgatt ccttctatcg agaaatacta tctattcttg gaaacttgga acagtagggg
    14881 gagattgact atgctttgga aattatcact tactgggatc aagagccgtt taagagacta
    14941 cttggtgtta ttctcaggat tagttatggc atctgctatt ttttacatgt ttgaatcaat
    15001 ggcaagcaac gaagcttttt tgaaaagtaa tacgatcgtt gcggctacag ttatcatttt
    15061 ccgattcggt tctgttttac tagggatcat cacattcgtt tatattttat atgcaaattc
    15121 ctttttgatg acgatgcggc aaaaagacta tgcaatgttt atgatgctgg gagcaaaagg
    15181 cagaaaaatc gcacagatga ttttttctga aacattctta gtagggatcg cagctacttt
    15241 agtgggttca gctgtcggtg taggattgac aagtatcgtc caccgattat tagtggatca
    15301 gttagatctc aatatttcgc attttacacc ttttagtatt cacgggttgt tgatcactgt
    15361 tttgtttttt gctgttttgt ttttattagc tgctgttgtc aatgcttttt cgattgtcaa
    15421 aaaaccgatt ttagcattga ttcgtgcgga tcagacacca acaagaatca agcagcataa
    15481 attcttgttt ttccttgaag tagtactggg aattgctttt ctaggctgcg gttactatat
    15541 gatgaaacac gtggggacct atcaagtctt tggtataggg gtagccttag ttacgatcat
    15601 attaggaact tatttcattt tccattctgt gatcattttc tttttatcat tactaaagaa
    15661 atcagaacag atttcattga aaaaattgaa caatttcaca ttgtcacagt taaactttcg
    15721 tattcgtgaa tatacacaaa tgctctcaat ggtcgctatg ctgtttgcct tggcactggg
    15781 cgctttgacg gtaggattag gttttaaaaa tgaaattgca gacttgacag aaaacaattc
    15841 tggatatgat ctagtgatga ataatcctcg ggcagaagat cagcaaaaaa tcaaagaact
    15901 ttcaccaaca ctttctgctt cttatactca aaaagaagat gcgggaacga tttactataa
    15961 tgcaagtgaa tttgcggctc aaccattgat catgataaaa catgaagatg gaacaccgcc
    16021 gaagatcacg aaagaaaaag ttcctgctaa aaaaatgaat gaactgactg tacaagagga
    16081 acttcgaagc tatgaattgc cggaacagca agaaaaagaa atcaaggtag tcagtcaatc
    16141 agaatttgat caactgaact tgccacaatc cactttacag ctagttcagg taaaagactt
    16201 ccaagcaaac ctgaaaccaa tcgaaacact tgttgctcaa aataaaatga acaatccatc
    16261 tttgcaaaaa gtagagtaca gcaaccagaa atatgaaatg tatgaagtgt ataatggtct
    16321 attctctggt tttgaattta tgggattctt cctaggttta gctttcttga ccatgcttgc
    16381 tagctgtttg atgttcaaga tcttgtcagg aagcaagagt gacattgctc gttatgaaat
    16441 gcttgaaaag ataggaacac gacgcgggtt gcttaaacaa tcgatccgta gagaagtagg
    16501 cgtgttattc ttagcaccag gaatcttagg tgtagtccat gtcttattcg gattacaaat
    16561 gtttggtcta ttcatgcaaa atccatacaa agatatttgg gttccgttta cgatcttctt
    16621 cgtattgtat ttcatctact atgtactgac gacatggtta tatactggaa tcgtattgaa
    16681 aaagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaag caaaaatagc
    16741 tcctcatatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    16801 tgttcggaaa aagaggttgt gacaatattt ttgtcacaac ctttttttca cggtctttta
    16861 ttagaatata gtaaattttt tctcgttact cacggaataa gctgttaaga aaacggtttc
    16921 catgtatact ggaatcagtg caaatgaaag aaaagagggt gcaaggaaca tggaaatcaa
    16981 tgaacaaaat tttggcgaaa actatcactt gattacgatc acgaatcaaa atgggacatc
    17041 tttgtctgtc agtgatcttg gggcacgggt tgttcatttt caaacaataa tcgataatga
    17101 aaaacgagag ttgatcttag gttttgatga agcaaaagaa tatctagaaa aagaccctta
    17161 tatcggtgct tcaatcggac gtatggctgg acggattacg aatggcacat tcaaattaga
    17221 tgatgaaacg ttcgaagtaa aaacagaccc ggacactggt cattgtttac atggtggtgc
    17281 acctagcttt gaagccaagc agtggcatta tacagtcatc aatggtgaaa acgaagcatc
    17341 ggtcattttc tatcagacta gcccagatat ggaaaacgga tttcctggaa ctttagatgt
    17401 agaagtacgg tatacgctga cgaacgatga tacatggcga gtgacggtcc aagggatcag
    17461 tgaccgcaaa acagtattca atcctacaaa tcatgtctat ttcaatttaa ccggtgatcc
    17521 agcacagtca atcgacgaac atatactttg gttgaatagc cgattatttg ctacgctcaa
    17581 taaagataca acgcctacag gagaagtagt ttcagtaagt ggcacagcat ttgacttcca
    17641 acgtcctaaa aaattaggtg aggtctttgc cagtgatttt cgccaatcaa tgatagtggg
    17701 cggcatcgat catccatttt tgttgaaaaa acaatctggt ttactaaatg ctgcggaatt
    17761 gacaagccca gatgaaaaag tatcgatcca agtaaaaaca gatgcttcag gaatcgtgat
    17821 ttttacagca aattttggag aagatggacc ggaaatgcgc gggaataaat tagtaaatca
    17881 tggcggtatc acatttgaga ctcaagaact gccaggagcg gagcgacttg aaagttttgg
    17941 agatgtcact ctggaaccta accaagtacg cgagtttgta acggaataca aaataaatat
    18001 aaagaaatag aataaattaa aaagggagtg tgacagtgtc acatcccctt tttaatttat
    18061 tctatttctt taaaggcaga tcaagccaga atgatttgtc taaacttaac aaggttagta
    18121 caggaacagt tgcagcttta actgtacgag tagttgtttc tggtatctgt cttgccgtaa
    18181 aattgttcca caaatcccag attgaagcga cacggaagat ggaagaagcg ttgttgacgc
    18241 gttttatcgt tgaaaattct aatcctgtga ttggcacgcc atctgttgtc catttgattg
    18301 gcacatcgaa tcgcttagac atattgagga tttcagcgtt tgcttcttca gttgttgctg
    18361 cttctttttt cggttcatca tattttgtca ggtcgtacgc ttcgatgatc gcgttcaatt
    18421 tttgtgaata ttggcgatct gtagcataac gtccttccaa atatttggtt gcttctttgt
    18481 agtcttttgt ttccgacttc caagttggtt tgtagaaatc aggattgcca gtcagtccat
    18541 ttttgatcaa gtcggcatag tcttccaaac tttccttgta agaaggatat ttacggaatt
    18601 gtgcgcggat ttggtagctt tgtccggaac tatcttgttc aagtgtattg aaggtcacgc
    18661 tgcttccttt atatgatcct ttgataccaa aaaggttatg atttggttcg cttgataata
    18721 agctgtttcc agatccactt tcaaggatag cttgagccat catgactgat gcgtagattc
    18781 cttctttttg cccgatttcc tgtgcatcat ctgcaatctt tttcaagaac tgatcagttg
    18841 tttggttttg actgaaatgg aacgagccat ctaatccatc taaaatagat gagccgcctg
    18901 tcagcgaacc tgaagcagca ggtaaacctg ctaagtttac tcggacagca aaatcaggcg
    18961 tgaaatctga aatagaagtt actcgaactt tatctcctgg ttgaggcgca tggataaatt
    19021 gtccgttccc aatatagata cctacatggt gagtaacacc ggaagaaggt ccccagaaga
    19081 cgagatcgcc aggttgggcc tgacttactg gaatctgcgt acctgcatat tgctgttcgc
    19141 ctgtccagcc accgatataa tgaccggttg ctttcatata tacgtaataa gtcaaaccag
    19201 aacagtcaaa agtatttgga ccttttgctc cccatacata tggttttcca agatgcttga
    19261 atgcttctcg aacgattgct tgttggacat tcgttgtatt tgtaggcaat acagcatcaa
    19321 ttggtgattt tacaacaaaa tcagaagaag cagaagatgg attctctata ccgctttgat
    19381 ttgctgtatt tggacgagat gaagcattgt tcgttccgcc attcgatgaa ccattgtttg
    19441 gatggtttgg ttctctctga gtatttccat tgttattcga tccagatggg tttgtttgat
    19501 tcgaagaatt cccgctgttc gaattattgt tattattgtt tgaattattt gaaccattat
    19561 tattgttgtt attacccaca tctggtttgt ttggcgtttc cggatctggt gtactaggga
    19621 cttcttcact aggatcagtt ggtttctctg ttgaagtatc cggtccagct ttaaattctg
    19681 cagtaataga taaattgttc gtacctactg taaaggtctt tgcatcataa tttacttctt
    19741 tggcaccatt aacagcgact gaagcaattt gttcaccttc agctggcgta atagtgtaag
    19801 ttaccttcgt ttccgctaat aaaccttcta ccgttccact ttccgtaata tccaaaggtt
    19861 gctgttcagg ggaatccgct gtcgaagcag tcagttggat cttaccaatc aaagaaggag
    19921 caattgtaag ggaatatgtc tcggctggct tttcattttc tgatggatca gccggatcaa
    19981 tttcagttgg ctcggtcgat cctgttgttg agttagttgt tccagttggg tcttctgtaa
    20041 aagaatccgt tgtttcacta gtagctgagc tggatgtagt cgtatctgtt gtgactgttt
    20101 gatcagctat ttgattatct acggcaaata cggtattggt cgacaaaaca gacggagcaa
    20161 tcagccaagt agcagctagc aaacgtatcg tttttttatt tttcataata aactagtcct
    20221 tttcctttca ttgattttct gtcttattca gcattcatta gacatttttt ggaacagata
    20281 atcgtgtcga aaagcttttt cttttcataa atctgtctgt gtattctaaa taaaacaatt
    20341 tgtaaataag caacgagcat tcattcgttt ttctttgacg ttcattttat tgcatagacc
    20401 acctttgttt ggggataaac aagtggggat aaaaatggtt atgcatatgt aaattatacc
    20461 aaagtttgga aagtatcaca aaaatttata aaaataatga tcctaaaaag aaaaagactg
    20521 aaatatgtga taaacatctc atacttcagt ctttttcatt aactattcat aagacattag
    20581 gtcttcatca aacccgctaa cgagagtagt gatcattgct acgactagac taacagccag
    20641 tcctgctaag taccagaaaa aagtaccgga aatgaatgca ggcaatgtgg tcagactacc
    20701 aaatacaaaa gcgatcgctt tcacttgggc aaatcccatt acagctccac cagcagctgc
    20761 accaatgcaa gcagcaacaa atggtttttt caatgggatc gcaattccgt aaacagttgg
    20821 ttcggtcact cccgcaagta aaatcgaagc aaaagcagaa ccggagatcg aacgggtttt
    20881 tgaacgttta cttcgcagaa atacacctaa agctgcacca gccattccaa aattggctgc
    20941 tcctgtcaac ggaacgattc ggtcgaaccc ataagcagag atattactga tcatgacagg
    21001 gtttacagcc cattggatac caaatattac caaaatattc caaccaccag cgatgattgc
    21061 gccactgatc ggtccgttaa tatccatcat ccaagtaatt gcggcagcta aaccttcgcc
    21121 aaggtaaaca cccgcaggcc cgaataccat taacgtcaaa ggaaccgtga taactaatga
    21181 aagtaaaggt acaaatacta attgcatatt ttcgcgaata tattttttga ggaatttttc
    21241 aacaaaagaa taaaagaaaa tacctaaaat cgccggcatg acagtagacg tatactgcat
    21301 cagtactaca ggaatcccca gaaaatcagt agctgctttg ccactgtctg aaagtaaaga
    21361 ggtcagattc ggttcaatca gtgctgcagc aatgacagcc gcaatatatc cattcacttt
    21421 aaacgttttg gcagcagaaa aagcaagaaa gattggcaga aaataaaaga cggcattcga
    21481 cgcagcagac aaaatatgat aagttccgct tgtttcacta agccagccaa tcgtagtcgc
    21541 taaaacaacc agacctttta atataccaga accggcaaac agcggaatga tcggcgtaaa
    21601 gatttccgat atcaaaccaa atagtttttc gatcggattt agcttttctt tcggagctga
    21661 atgatcgatt tgacgcgtca attccttgta agcaggagcc aatccctgat ccatgattat
    21721 ttctgcatat ctatcgagta aaatgaaata cttaatggaa gggatttgct gttttaattt
    21781 ttctgcattg gctactggct gttttttcaa tttgatacga agccgagtcg cacatggaag
    21841 gacagaatca atattgtctt ttcctcccaa ctgttcaatc agcatatgaa tctgctcgga
    21901 cagtaccatc tgttcaggat tcattgtcgt ttccattaga agaccactcc actcactaat
    21961 ataatattgg cgtaaggtgt catttcgcct gtacgaataa atgcatgaca gttattcaac
    22021 tcttttttca tttcttcatg tgggataaag ctaatcggtg tatctggtaa caataatttg
    22081 attttttcca atatttccgg gttcattgtc tttatttctt ccgccaattc aatcgattgt
    22141 acctcaagtt cttctaaaac gttttctaaa acagataaaa aacttggaag accgtttgag
    22201 acagccaaat ctattttttc agtaccaaag gggacaggca tgcctgcatc cccgatactt
    22261 aatttatcaa agtgccccat ttgtgcgatt actcgtgaaa tatctgaatt gattactttt
    22321 ccttttttca tgtttgtttc ttcctctcat tgttaatttt agactgctga ttgttctaaa
    22381 gcttcgcggt aagggataga aggttgcgca ccataagact gcacagcaac agaagaggct
    22441 agatttccat aaaggatcgc ttctttcaag ttactaaggt ctggctgaag tgtgctgctt
    22501 aatgcgccaa taaatgtatc acctgcggct gttgtgtcaa cggcatccac tttaaaagca
    22561 gggacgatac cgtgttcttt ttctgtatga tagaaagcgc cggcactgcc tagtgtaatg
    22621 attactgttc caatacctaa ttcatggagt ttttcggctg ctgcgaccaa actgttatga
    22681 tctgtcactc tgattcctgt aatgatttct gtttctgttt catttggtat aatgatatct
    22741 gtcttttcaa gtagttcagt aggaatcgtt tcacgagctg gtgcaggatt caggatcgtt
    22801 gtttttcctg cgtcttttgc aatagaaaaa gctaggatcg tcgcatctaa gctactttca
    22861 aactgagcaa taataaagtc actgtttgta atcagttgct tgttttttag gacttcttgt
    22921 tcatggaaag cattatttgc ccctgcatgg atcaagatac tattttctcc tgctgcgtct
    22981 accataatca ttgcttgtcc ggttgtggcg ccttggattt cagctatccc agatgtatcg
    23041 atgttttctt ttgtcagtag atctaataac tgttgtcctt cgctgtcagc cccaacgcct
    23101 ccaataaaag atgtccgtgc gcctgaacgt ttggctgcca ctgcttggtt ggcaccttta
    23161 cctccgccag cgtgaaaaat ctcatgcgca tgcatcgttt cgcctggctt gggcatgttg
    23221 gttaaacgaa gggtagtgtc catattaata cttccaatta ctgtaaccgt gttcatttta
    23281 caaacctcca actatctcat ttattttgat gggaaaatta ttttttaaaa cgttttagta
    23341 aaacgtttta atagttcgat aaaaatatag cacaccttga aagctatttc aagggtgcag
    23401 ttgaaaatct tttttctaat cgtacaggta atcttttttc ttcccattct ttttctggga
    23461 attggatccg atctaacaat aacttggcag atgtttgtcc caattcgaag attggttgtg
    23521 cgatcgttgt cagtttcggc ttgatatact cgcacatatc tatattatca tagccaataa
    23581 tgctgtagtc ttcagggatg ctttttccag cttcctctaa tccgcgatat aatccaaaag
    23641 ctaattcatc atttaaagca aacacaccag ttgcagcaga atcaagaagt tctgctgtga
    23701 tctggtagcc accttgtttt gagaactgtg taggtaagag gatcagttgg tcgtgaggga
    23761 tttggtaaac atcaagagca gatttaaacc cctcaatccg agcgtggaca ttttccggtg
    23821 gattttcagg atagacaagg gcgatcgttt gatgtcctag actaagcaag tgcatgcccg
    23881 ctaggtaacc accgcgaaaa tcgtctgttc gtacggcatc actaaatcct tcagattttt
    23941 tctgatccaa aacaatgaag ggccggcctt gttttttcaa attttcgttg attgcatctg
    24001 tagagacagc agaagtcgcg ataatgaatc catccacacc tcgacgtgtg agctcggcta
    24061 gatattcgat ttctttttga tgatcagaat cagcattaca taatatcgtg acgaaattct
    24121 gcttatacaa gatatcctca attcctcgca tcagtgtact gaagaatgga ttcgtgatat
    24181 caggaacgag tacaccaatt gttttcgttt ccttggtaat catttgtcta gcaaaatagt
    24241 caggctgata gcctaattct tctttggcag ctaaaacttt ctgaacagtt ttcggactga
    24301 atttctccgt atttccattt aatatcaagg agacagttgt gattgaaacg ccggaaagtt
    24361 tagcgacttc tttgattgtg atcttttttt tcaccatgtt catactccta tctaaatcct
    24421 gtggttattt tcccatgaaa tcaaaaagaa gtaaatgaaa atcaagtgtg ccagtactta
    24481 tttgctttgt tggatagctt cgattatttg tttcgttgag cgtactcgtg cagttttcgg
    24541 aaatatcttt tttatgaaca attgatggga ttctttgtca cgatcactgc aagcatcttc
    24601 agcaagcacg atatggtacc cgtgttgaaa ggcatctaat gcagtagcat atacaccgtt
    24661 tgttgtcgct acaccgctta aaatgatagt ttcgattcca cgccggcgaa gttgaagatc
    24721 aagagaagta ccaaaaaaag cacttggatt gtattttttg atagtcaaca tattatctgt
    24781 atctttcaaa gaatccttca aaagtaaatc agtgaattct ggaggtacag aagcagtcat
    24841 tccacccata tcagtttgtt gactcaaata agggaaagtg gagatgtcta cgttcactaa
    24901 aactttcaag gcagcggtac gtttcaatgt tcttactaac aaatcattgt ttgtcagaat
    24961 agatgctgca gtgtgtggag agagtgtacc gttatttacg atctcttttt gcatgtcgat
    25021 cgcgacaaaa gcagtttttg ataaatcaaa aatcatattt tcctttaaat cattcatgat
    25081 gttccttctt tcaaataaca atgtttttta tgtaagtaaa tcataaatcg tttatttgtc
    25141 aactaaatta aaggattcct ttctttagtc tagagaaatt cagtggtaaa ataaataagt
    25201 gtgagaaaac gcattcgatg catagatata gcgagaaata tcgtgaaaat ggaggaatca
    25261 gagtgaagta tgtcgaagta aaaaatgaat acaaacgata caaaatggga gaaacgacca
    25321 ttacagcaaa tgacgatatt tctttttcaa ttgaaaaagg cgaattagtg attatacttg
    25381 gtccaagtgg agcaggaaag tcaacgattc ttaatatttt aggtgggatg gatacacctg
    25441 atgaaggtca gatcattatt gatgacacag atattgcgca attttcagat aaacagctta
    25501 ctgcttaccg acgaacagat gtagggttcg ttttccaatt ctacaatctc gttcctaatc
    25561 taacagcaaa agaaaatgtg gaattggcaa cggaagtttc tcctgatgcg cttgatcctg
    25621 tagaggtatt gaggcaagtg ggcctagctc atcgattgaa taactttccg tcccaattat
    25681 caggaggcga acagcagagg gtttcaattg ctcgtgcact agctaaaaat cccaaacttc
    25741 ttttatgtga tgaaccgaca ggcgcgctgg attttgaaac gggcaagcaa gtattgaaat
    25801 tattgcaaaa cgctagcaga caacacggca ataccgtttt gatcattaca cataattctg
    25861 ctttagcgcc catcgctgat agagtcattc acattaatga tgctaaagta aggtctgttg
    25921 aattaaatga tcatccttca tccattgatg agattgtatg gtagggggat tttatgaaaa
    25981 caagaacata tcttaaagca ggttttcgcg aaattcggca atctaaagga cgattcattg
    26041 caatcatcct tattgtcatg ctaggaacac ttttatttgt aggtgtcaaa actgctggac
    26101 ctgtcatgca aaaaacgatg gatcactatg ttggtacagc aggactttct gatttgcaaa
    26161 tcgtttctac tggtggcttg acacaaaaag atattgctca agcagaaaag atcccagatg
    26221 caaaagtaga aacaggaaaa cagatctatt attccaatac tggcaaaaac gaagtgattc
    26281 aaatattttc ttataacaaa aataacaagc agaacaagct acaattaact gatggaaaac
    26341 tcccggaaaa accaaaccag cttgtattgg atgaaaaagc ggaagatgaa gggtataaaa
    26401 tcggtgatat ttatcagatt gattcagatg aattgaaaga aaaagagtat accatcacgg
    26461 gctttgtccg ttctccattg ttcatcaaca atttggagag aggatacgcg aacgtcggaa
    26521 atggtagcgt cgattatttt gtctatttac ctgaatccgt ttttaaaaca gatatttatt
    26581 ctgtcttata tcttgatttt acaaacgtaa agaatttgaa tacgtacagc aaagcttaca
    26641 aagataaaat ggagcaaaat caagaaaagg cagaaaagta tttacaagat cgacccgaag
    26701 aacgcttaga agagctgaaa aaatcggcca acgaagaatt agaaccggca cagcaaaaaa
    26761 tagcggatgg caaagcacaa acaacgcaag caagaacacg gttagaagat gctaaaaaac
    26821 agttagcgca acagtcagca actatccagc agcttcctga agcgcaacga acaatcgctg
    26881 ttcaaacatt acctcaacaa gaagctcaac ttgctgaaca agaaaggcaa ttagttgaga
    26941 aagaacgtga actggcctct gcagaggaag aattgaatcg aaatgcagaa aaaattgaaa
    27001 atttaactaa accatcatac ctatacaatg aacgttcaga aaatgtcggt tttcaagaat
    27061 ttggtgatct gtctgatcgt atcgctgcga ttgccaatgt ttttcctgtt ttctttttct
    27121 ttattgccgc attgatcacc tttacgacaa tgacacgtat ggtagaagaa aaccgcaggg
    27181 aaatcgggac attaaaggcg ttaggttata cgaaagttga aatcgcaaaa aaatatgcaa
    27241 tctatgcaag tctagcctca gggataggta ttgttttagg aacgatatta ggaacgaatc
    27301 ttttgccaag gatcattttt gagctgtcta acgagcggta tgatattggg agtgcgctta
    27361 ttttttatga ctggccgccg attttacaag cagctgccgc attcttcatt gccgcatttg
    27421 gcgctgcaat gatcgtttta ttcaaagatt taagagaacg gcctgctgca ttgcttcaac
    27481 cgaaagcacc gaagccaggg aaacgcattt ttcttgaata catcactccg ctgtggtcac
    27541 gccttagctt taatcaaaaa atcagttacc gaaatctctt ccgatataag tcaagaatgc
    27601 ttatggcgat tatcggaatt gctggatgtg ccgggctgat ggttgcaggc gtgggattga
    27661 aagattctct aagttctgtt tcagccaaac aatttggacc gatcattgac tatcaagcaa
    27721 tcgttacatt ggattcatcc acggaagata gtcgtcaaaa agcagcggat atgctgcaga
    27781 agcaagaaaa agtaaatgag atcctagcta ttcatactca aaccgtagaa ttgagaaaaa
    27841 aaggacatgc ttcgcaaagt ctgacagtga tcgtaccaag taaaacagct gatttggatc
    27901 gttttatcca tttaactgat cttgaagaga acccacgctc cttgcctaaa acaggaatcg
    27961 ctattacgca aaaagtagca gaactatttg acttatctac aggagatcat atttcgcttt
    28021 atgatgaaga tcaaaaagaa tggaaagtcg aagtaaaaga aatcgtgaaa aactatctag
    28081 gtagctttat ttatatgtcc cctgaatatt atgcttcagt tactgatcaa tcgatgatgg
    28141 ataatgcatt tttgctgcgt acagataaga tgacaacaaa agaagaagaa atgctttccg
    28201 agaaactgct tgccacagac gctgtgacaa atacgtcttt catgtccaaa caaatcgaaa
    28261 cgcaagaaga atcaatggcg aacttagact cggttgtctt aatctttgtc gtattatcag
    28321 gactgctggc ttttatcgtc ttgtataatc taactaatat caatatttcc gagcgtgtac
    28381 gcgaattatc tacaataaaa gtccttggat tttttgataa agaagtcacg atgtacattg
    28441 ttcgagaaaa tatcatcttt actcttttag gaatcatcgg aggatttggt gtaggatata
    28501 tattgactga cttcatcttg caacaagcgt ctatggagaa tgtcatcttt ccattagtga
    28561 tcacatggtg ggcttatgtc ttatcagcag gattaactat cgtatttacg gttattgtga
    28621 tgattgttac ccatttcaaa ttaaagcata tcgatatgat tgatgcgttg aaatcgaatg
    28681 aataaaaaca gaggttgtga aatcagcgtt ttgagctaat aacgagggtc agctgctaat
    28741 tgaacaccat gaatcagagg ttgtaaaaaa gccgtcctgc atcgagcaaa aagaatactc
    28801 aaataaaatt agctcctcat gttttacatt tgagaagact gattgccgta gataaaagct
    28861 tttgaacacc atttatagaa gaaacaagaa tattttgcta ttttaaacaa gaggatagac
    28921 aaatacatgt ctgatctctt gttttttatt gggcaacaga cctcttagaa tgtataaaga
    28981 taaattttac aaacgctttc tgttcagtta taataataaa tgataacttg tatatataag
    29041 ctgtggtagg taataaatca gttgaatgga ggtaaatatc catgacattt aaagacaaag
    29101 tcatttacca aatctatccc aaatcttaca aagacagtaa tggtgatgga attggagatt
    29161 taaaaggaat caaagaaaaa ctcccgtatc tgaatgatct aggcatcgac atgatttggc
    29221 taaaccctat ttatccaagc cctcaaaaag acaacggtta tgatatctct gattacacag
    29281 ccatcgatcc tatctttggt acgatggagg aattcgaaca gctaatagcc gaagcaaaga
    29341 aataccggat agaaatcatg ctcgatatgg tgctgaatca cgtttcgaca gaacatgaat
    29401 ggttcaaaaa agcactagca ggggaccagc attatcagga cttcttcatt ttaagagaag
    29461 agccaacgga ttgggtatca aaatttggtg gaagtgcttg gtcgccattt ggagatacgg
    29521 ggaaatatta tttgcactta tatgatcgga cacaagctga cttgaactgg cggaaccaag
    29581 cagtaagaga ggaactattc aaagttgttc gtttttggat ggaaaaaggg gtaaaaggat
    29641 tccgtttcga tgttatcaat gttatcggta aagacgaaca attgaaaaat aataaagaaa
    29701 atgatggcaa acctgaatat acggacaaac caatcaccca tacgtatcta aaagaattga
    29761 accaagcaac gtttgggacg gattccacta tcatcacagt cggtgaaatg agctctacga
    29821 cgatcgaaaa ttgtatcttg tatacagaac ctagtagaga agaattatca atggtcttta
    29881 atttccatca tttgaaagtc gattatgaaa atgggaataa atggtctact cctccatttg
    29941 attttgcaga attaaagcga ctatttcata catggggaga aaatatgagt gagggtaacg
    30001 gctggaatgc tctatttttt aataatcatg atcagccacg tgcgctcaat cgatttgtag
    30061 ttatcgatca gtatcgaaaa caaggagcag agatgctagc aaccatgatc catttgaacc
    30121 gtgggacgcc ctatatttat atgggagaag aaatcggcat gatcgaccca gactattcat
    30181 cgatttccga ctatattgac gtagaaagtt tgaatgctta taagttactc cttgaacaag
    30241 gattcacaga aaaagaagcg tttcgtcgga tcaaagcaaa atctcgcgat aactctcgaa
    30301 cacccatgca atggtcagac acagaacaag caggatttac tacagggaaa ccttggttaa
    30361 aagttggagg caagctagaa gagattaatg tagaaaaaga actatcttct gaagattcta
    30421 ttttgtccta ttacaagaaa ttgattcggc tgagaaaaac atatccaatc gttgcacaag
    30481 gagattatca tgcttatgaa gcaaatcatc cggaagttta tggctttctt cgccaatttg
    30541 aaggacagca gctgcttgta ttaacaaatt tctatgataa agatacaagg atcgccatcc
    30601 cagaaggatt cacagaagcc aatattctta tcgataatta ttccgatact gttcttcatc
    30661 aaagtctgga gctaaaacca taccaggcaa ttgctttgct gaaaaattaa aacaaaaaca
    30721 caaaacgtcg ttcctacgag ctattctcgt aagatcgacg ttttgtgttt tatttaaaat
    30781 aatcttcttc agaaaatgaa gagttttcat actctccttt atcgccataa aatttattgt
    30841 agcgttgttt gaatttacgg aaaataaaag taacgagtaa tttgactaac gtatagatag
    30901 gaataccaaa aataacgccc acaattccca ttagatcacc catgacaagt aaaacgatta
    30961 agatcgtaat cggatggatc tgtaaacgat cacccattac tcgaggaatc accaagtcac
    31021 cgtggagaag ttgtacggca aaccagacaa tgacaaattt gacagccata aaagtagagt
    31081 cttggaatgc aatgatcaaa cctggaaaga aggcgataaa cggcccaata tatggaatga
    31141 tacataacaa cccagcagaa atagctaaaa cactagcaaa ttctaatccg atcagtaaga
    31201 aacaaaccca gtagactgct ccaaggataa atgaagcaat gatttgcccc tttagaaatg
    31261 aacccaattg ttgattagca atctttgtca aatttttaaa atctgtacga aatgctggtg
    31321 ggacaatcgc taaaactgac tgataaaatt tttgaggatc tctcaaaagg aaaaaagcga
    31381 caattggacc agtaaataaa gtaataaaaa tagctgtaac agttgaaaaa atgttgctga
    31441 tccgttgtgc gccactttcc caataatttc caataaatcc agctatatca gacgtcacgt
    31501 cgtcaataga agcaaaaaat tgattaaatg aatcggcaaa aggtgttttc tccaaaaatt
    31561 gtcggagact ctcttgaaaa tcttgaaaca aatctggcaa actactgatc aatgtctttg
    31621 cctgttcttc aagaaaagga ataagccata tgcttccaag ccccaataaa aataaaataa
    31681 tcacataaac gataatgact gacaagttcc tcgaaaggtg cttgctcaaa cgtttgatga
    31741 ctggttccaa aagataatac aagatcagtg caaacaataa tgggggcaag atagtagcga
    31801 taatgattcc gacaggcttg aatataaacg agatctgatg gaaaaaataa atgatcagcg
    31861 caagtaagat aactattcct aaaacatagt aagaggtttt tcctcctaaa aagcggatca
    31921 aacgattcgt tgtatctgtt tcttttttca ctctttttcc tcctttatct ataacttcat
    31981 tatagacaaa agcgggtata aaaggaaaat gatagaggtt gattgcaaaa atatcgtcaa
    32041 tcattcatat aaactttctc atcaattaaa ataagaaaac gcttgacagt tcttttaacc
    32101 atatgataaa ttaaatcctg ttgctaaaac gtaactatta cggtttgcga aaagcgaatc
    32161 ggaacattca aatgaaagaa gatgagaaga ggagtgtcat aaatgaaacg attgataggt
    32221 atattggcca tgctggtttt agcaggtatg ttaactgctt gcggggcaag tgggaaagcc
    32281 gaggacagta aagaaaaatt gagcgtgatg acgacctttt atcccatgta tgattttaca
    32341 aaagcaatcg tcggggatga aggagaagta gagttattga ttccagcagg gactgattcc
    32401 cacgattatg aaccttctgc taaagacatg gcaaagatcc aagatacaga tatctttgtt
    32461 tataatgatg aaaacatgga aacatgggtc cccgcaatcc aaaaaacatt acaagaaggc
    32521 aatgtccata cgataaaagc gacagaaggt atgcttttac ttccgggaag tgaagaagga
    32581 catgatcatg accatgaaca cggggaagaa ggccatacac atgagctaga cccacatgta
    32641 tggctagctc caagtttagc aatcaagcag gtagcaaaca tacgtgatca gctgattgaa
    32701 gcttacccag aaaaacagga agtatggaca aaaaatgcag cagcctatac cgagaaactt
    32761 caagcactcc atcagcttta tcaagaaacc tttaagcaag caaaacaaag atcttttgtc
    32821 acgcaacatg ctgcattcaa ctatctagcg ttagaatatg gattgaatca agtatcgatt
    32881 gctggtcttt cttctagtga agaaccgtct gcggcgagaa ttgctgaact gaaacacttt
    32941 gttaaagaac atggaatcaa ctatatttat tttgaagaaa acgccaaaga tagtattgcc
    33001 agaacgttag caaacgaagc aggtgtatct ttagaagtat tgaatccttt ggaaggattg
    33061 acgaatgaac aaatagaaaa tggagaaaac tatctttcta tcatggaagc aaacctcgaa
    33121 gcgttgaaaa aaacgacaga gacagaaaac ccgctagaag atactttgac ccccaaaaaa
    33181 gaaaagagcg tctacaacgg ttattttgaa gacgaggatg tacaagatcg ctctctttca
    33241 gattgggcag gaacttggca aacagtagat acgtatgtag aagatgggac ttttgatcct
    33301 gtttttgaat ataaagaaaa attgaatcag gataagacag cacaagaata taaagaatat
    33361 tatacgaagg gctatcaaac agatattgct tcaatcaaga tcagtgagaa agagatggca
    33421 tttacgttta aggatggaac aacgaaacgt tcaaattatc gttatgtagg gaaagaaatc
    33481 ttgacctacg aggcaggaaa ccgtggcgta aggtatctat tcgaagcaga agataaggaa
    33541 agtggcgctt ttagatatat tcaattcagt gatcacacga ttgcaccggc tgactccgaa
    33601 cattttcatt tatatgcagg aaatgaaagt caagaagtat tgctgaaaga aatggagaat
    33661 tggccaacat tttatccaga tacaatggat ggacgtgaaa ttgcacagga aatgcttttg
    33721 cactgatagg caaaaaagaa ccgaagggtt tggatcggct ggtcatttag tcggtccaaa
    33781 ctattcggtt ctttttatga aatcaatttc tttaatccac ggatagaggc tgggatggtc
    33841 tcgccgtttg ccaacgtgac ttctctggtt tttttattaa tcgaccgcac attttgtgta
    33901 ttgataacat aggatttatg acaacggata aaattccgat gcattttctc gatttctttg
    33961 atcttctcat agaattgtaa ttgggcatga gtcaaatgga cttccagttt atgtggcgct
    34021 cctagcgaag tagaaaaata ttggatgtct ttgatcggta aaaatttgat ctcatcatta
    34081 aactctattt tgaagatatc tttttggatt tgggacattt gaaaatcttc gaaaattttg
    34141 ctcaggatat gctcgacatt ttcttttaaa tcataaagat cttctttgac gatataatca
    34201 gtcggttcga tgttgctttt taagattttc atcgacattt ccgtatggga agtcacatag
    34261 attatttttc ctaaaggatc taattcacgg atcaatttac cgatcgctac accatccatt
    34321 tcactgtctt ctagttcgat atctaaaaag taaataccaa aagaagaagt tctgatcttg
    34381 gctgcattga gaagttcttc cggatcagag gtagaaatat ggacataact gtctaagttt
    34441 tcaatcatga ttctattttt gatcaccgtt gataaaactt ctaattgttt tggatcgtct
    34501 tcacaaatat aaatgggaat catatcatta ctcctttatt ttatttgtat ataaatcgtt
    34561 tgagaaaaac gctggttttc aattgatgtt tcaaggaaaa gataaggatt ggtctttgtc
    34621 aattcatcca agataaacaa gccaaggcct tcgttttttg gatttgtttt tgttgagaac
    34681 cctttttgtt tcaactggtt taacggtaat gtatttgttg ttgtattgat cacacgaatc
    34741 atcacggaat gattcttctt gagtatggtc aattcgattt ttttcttctt tgcagcacta
    34801 gctccttcaa tcgcattgtc caagataata ccaagcatac gtacaaggtt taccgtatgt
    34861 ttcgtatcca gttcgattgg ctcaggaaaa tgaagctgga cgatcaaccc tttttcctgt
    34921 gccatcatga gttttaatga cagtaaacta cggatctcag gaactttcat attatccaac
    34981 atacttagat tggccggaaa aaggttcatc atctggcgtg taggtaatat cgtttgatca
    35041 taataagacc gtaatccttc taagtcgcct tctgaaatat agctgtgaag agaaaaaagc
    35101 agattttggt aatcatgttt gaattctctc aagtcttgat agtttttttc tagatctttg
    35161 atataatcct gttgcatcct gacttgttgc tctaataact gatcagctaa tttcttatta
    35221 gagattttcc aataataaac caagatgatc aggccaacac acagatatag aatgaaaaaa
    35281 ctcgtattca aagctaagac atcaggtgtt tcaccagaaa aacgggtata aaaaataatg
    35341 atatagtatg taaataatat caatgtcccg atcgtaccga tcatacggcg gtccacagtg
    35401 tgaaaccaag tctctaacga tttttttaaa caaaaagcta ataaagcaga taaaaaagcg
    35461 gataagacaa tgtgaaaata ctgcaatgaa tctcctggtt caataaccga agatttcaaa
    35521 acaaaaaaat cgtcgatgct tgttaagtga tctcctaaaa gcgacgtcaa taacccaaaa
    35581 ggaagcgcgt aaaccaattg ttgacgcgaa gtcgaaaaga agaaaaaagt aagcatcagc
    35641 attcctatag caattagagc agtaaaaatc cctaaaatcg aatagaccca tccaatcaaa
    35701 atacaagaaa tcagaatgac tcccgcaaac agatatttgt atcggatgtg atggtcaatc
    35761 aataagatac aaattgtgta aatcaaatat tgcaacgcta tggaccataa aaacataaag
    35821 tacagctccc attgattttt accaaattat agcacaatta gcgtattatt tttttaattt
    35881 ttcagggatt ttgaattcag aactcatacc aaagcagcaa ccagatacaa aaaagtcaga
    35941 taagttagtt aattgtttaa tgattgtttt tttcatgaaa gattcctcca aaattcatca
    36001 agtagtttgt aataggaagc aacgtagcta tttctaaaac aatcccaagt agcaaatagg
    36061 tagaaaagta agaagctgag aaaaataaag taatgagaga aaaaattaga aacatgctga
    36121 tcgccttctt taataatggg ggacgtttct cgggttcaat gggattgatt gctgtacctc
    36181 ttgatccata gcgaagcagt aacaaaaagc agctgattaa caaaaagacc atcattggga
    36241 aggagatagt caattgcaga tgtttcatca ccaagggaac gccccataaa taaagtagtg
    36301 tccacagcag acaaacgaat tcagagtcgg aatgcaatcc ataagcatat ctgcggatgc
    36361 agatataaga aagaaaggtg attcctgttt ccgcccatga gcctgtcacc agagaaaaga
    36421 ctagaacgac cgctagtttt ccaagattat tcaataaaac ttctaaggca aattttactt
    36481 ggacatacac catatcttct tccgatttgt ctccgctgaa taaggcttct aataatttgt
    36541 tcacaacttt atctttcatc tcatacgtac ctccaccaca aattttatgc taaaaaaaat
    36601 aaaaaacgtc ttttgtttca taaaaagtgg ttttgacatc aaaaccgtca tgatctccta
    36661 aaaaaatctt cgttttccaa gaaccttacc aaaaaaagtg acagttttga tacgaaaagt
    36721 actttttatg acaagtttgt gctttttcga gtgatttatg ttaaaaaatt actgacctta
    36781 taaaaggtga tggagggatt cttatggaaa atgaacaatt gtttgaagtc ggcgaaacat
    36841 atgcatttaa atctgattta tttgaatcac caataaaagg aaaaatagaa aaaatctatg
    36901 aaaatagtgt gatgatacgt gtcatgaaat gcgcagtaga agacaatgat accgctcata
    36961 atctgcactg gcagttagtt gtacgcaaat caagtacaat agaagaataa aaacagataa
    37021 aatgttgaga gcataaagag gttgtgagtc tcccgtttag ctctgagtta caaggaataa
    37081 tgttaaaaaa cagcttttca tgttttatga atattgcctt gtgaccgagg tgttggcagg
    37141 agaatactgt ttatttgaaa aaagggctgc gacaagactt ttgtcacagc ctttattttc
    37201 atgaatagga gttacttttg gctactttta gagaagtagc ttttaaggag cagataaagt
    37261 caaggctttt atttctataa atgaagtagt aaaatgaaga acagatttta ttacaggaag
    37321 gatgccgata attgtgatca ttgttgcagg aacgatcggt gcagggaaaa gcacactaac
    37381 tgaaatgctt gcccaagatt tagaaacaaa acctttttat gagaacgtgg aagataatga
    37441 agtattgccg ctattttatt ctaatccaga aaagtatact tttttattac agattttctt
    37501 tttgaacaaa cgctttttgg caatcaaaga tgctttcagc catgatgaca acgtactaga
    37561 ccgctccatc tacgaagata gtatgctgtt tcatttgaat gcagatttag ggcgtgtttc
    37621 tgaagtagaa gtaaagcagt atgaaggtct tttagaaacg atgctgaagg agttagaaga
    37681 aatttcgcca caaaagaaac cagatctact ggtttatatt cgtgtatcct ttgaaactat
    37741 gttagcgaga atcaaaaaaa gaggccggga atatgaacag ctagaacaag atcctgaact
    37801 ctattcctac tataaagaac tcaatcgacg atacgaagag tggtatgaac agtttgatat
    37861 atgtcccaaa atagtgatcg atggggacaa atatgatttc gtagccgatc cggcatgtgg
    37921 agaacaaatc gtacaagaaa tcaagatgcg ggcaaagaaa atgacagaag aggcagatgc
    37981 ccagtcgatc cgctacacta caaataaccc gaaagcaaag ggaatcttta caaataaata
    38041 atataaaaac taagcaaatt gctcactcgc agttt
//
LOCUS       DASHXG010000024        37777 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.024, whole genome shotgun sequence.
ACCESSION   DASHXG010000024 DASHXG010000000
VERSION     DASHXG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.024"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            172..516
                     /locus_tag="U2R59_001377"
     CDS             172..516
                     /locus_tag="U2R59_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEM8965778.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="U2R59_001378"
     CDS             517..936
                     /locus_tag="U2R59_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEM8965779.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="U2R59_001379"
     CDS             complement(1028..1378)
                     /locus_tag="U2R59_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965780.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="U2R59_001380"
     CDS             complement(1344..2675)
                     /locus_tag="U2R59_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HEM8965781.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="U2R59_001381"
     CDS             2931..3497
                     /locus_tag="U2R59_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8965782.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="U2R59_001382"
     tRNA            3642..3729
                     /locus_tag="U2R59_001382"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            complement(3781..4986)
                     /locus_tag="U2R59_001383"
     CDS             complement(3781..4986)
                     /locus_tag="U2R59_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8965783.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5124..6012)
                     /locus_tag="U2R59_001384"
                     /pseudo
     CDS             complement(5124..6012)
                     /locus_tag="U2R59_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6099..6299)
                     /locus_tag="U2R59_001385"
     CDS             complement(6099..6299)
                     /locus_tag="U2R59_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965784.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6328..6750)
                     /locus_tag="U2R59_001386"
     CDS             complement(6328..6750)
                     /locus_tag="U2R59_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8965785.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6767..7189)
                     /locus_tag="U2R59_001387"
     CDS             complement(6767..7189)
                     /locus_tag="U2R59_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965786.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7480..7671
                     /locus_tag="U2R59_001388"
     CDS             7480..7671
                     /locus_tag="U2R59_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965787.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7682..7948
                     /locus_tag="U2R59_001389"
     CDS             7682..7948
                     /locus_tag="U2R59_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965788.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            7960..8130
                     /locus_tag="U2R59_001390"
     CDS             7960..8130
                     /locus_tag="U2R59_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965789.1"
                     /translation="MGKFNRTLVFSAPLIIYALGLWGSRQALIGTIVYMLWIFIGLDE
                     AEYRAKKPVGRD"
     gene            complement(8189..8668)
                     /locus_tag="U2R59_001391"
     CDS             complement(8189..8668)
                     /locus_tag="U2R59_001391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965790.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8713..9420
                     /locus_tag="U2R59_001392"
     CDS             8713..9420
                     /locus_tag="U2R59_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEM8965791.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9599..9940
                     /locus_tag="U2R59_001393"
     CDS             9599..9940
                     /locus_tag="U2R59_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965792.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9933..10679
                     /locus_tag="U2R59_001394"
     CDS             9933..10679
                     /locus_tag="U2R59_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HEM8965793.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10685..11371
                     /locus_tag="U2R59_001395"
     CDS             10685..11371
                     /locus_tag="U2R59_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965794.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11378..12211
                     /locus_tag="U2R59_001396"
     CDS             11378..12211
                     /locus_tag="U2R59_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEM8965795.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12228..13079
                     /locus_tag="U2R59_001397"
     CDS             12228..13079
                     /locus_tag="U2R59_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8965796.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13076..13435
                     /locus_tag="U2R59_001398"
     CDS             13076..13435
                     /locus_tag="U2R59_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HEM8965797.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13450..13611
                     /locus_tag="U2R59_001399"
     CDS             13450..13611
                     /locus_tag="U2R59_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEM8965798.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13614..13913
                     /locus_tag="U2R59_001400"
     CDS             13614..13913
                     /locus_tag="U2R59_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965799.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13913..14227
                     /locus_tag="U2R59_001401"
     CDS             13913..14227
                     /locus_tag="U2R59_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HEM8965800.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14404..14715
                     /locus_tag="U2R59_001402"
     CDS             14404..14715
                     /locus_tag="U2R59_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HEM8965801.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14712..14930
                     /locus_tag="U2R59_001403"
     CDS             14712..14930
                     /locus_tag="U2R59_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HEM8965802.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14943..15224
                     /locus_tag="U2R59_001404"
     CDS             14943..15224
                     /locus_tag="U2R59_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965803.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15221..15547
                     /locus_tag="U2R59_001405"
     CDS             15221..15547
                     /locus_tag="U2R59_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965804.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15544..15741
                     /locus_tag="U2R59_001406"
     CDS             15544..15741
                     /locus_tag="U2R59_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965805.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15738..15947
                     /locus_tag="U2R59_001407"
     CDS             15738..15947
                     /locus_tag="U2R59_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965806.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15944..16231
                     /locus_tag="U2R59_001408"
     CDS             15944..16231
                     /locus_tag="U2R59_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965807.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            16823..17288
                     /locus_tag="U2R59_001409"
                     /pseudo
     CDS             16823..17288
                     /locus_tag="U2R59_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
     gene            17587..17928
                     /locus_tag="U2R59_001410"
     CDS             17587..17928
                     /locus_tag="U2R59_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965808.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(17921..18112)
                     /locus_tag="U2R59_001411"
     CDS             complement(17921..18112)
                     /locus_tag="U2R59_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HEM8965809.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            18462..18674
                     /locus_tag="U2R59_001412"
     CDS             18462..18674
                     /locus_tag="U2R59_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965810.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            18681..18905
                     /locus_tag="U2R59_001413"
     CDS             18681..18905
                     /locus_tag="U2R59_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965811.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            18932..19465
                     /locus_tag="U2R59_001414"
     CDS             18932..19465
                     /locus_tag="U2R59_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEM8965812.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            19452..20696
                     /locus_tag="U2R59_001415"
     CDS             19452..20696
                     /locus_tag="U2R59_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEM8965813.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            20709..22208
                     /locus_tag="U2R59_001416"
     CDS             20709..22208
                     /locus_tag="U2R59_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8965814.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            22213..23139
                     /locus_tag="U2R59_001417"
     CDS             22213..23139
                     /locus_tag="U2R59_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEM8965815.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            23266..23868
                     /locus_tag="U2R59_001418"
     CDS             23266..23868
                     /locus_tag="U2R59_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEM8965816.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            23881..24804
                     /locus_tag="U2R59_001419"
     CDS             23881..24804
                     /locus_tag="U2R59_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEM8965817.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            24822..25085
                     /locus_tag="U2R59_001420"
     CDS             24822..25085
                     /locus_tag="U2R59_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965818.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            25097..25426
                     /locus_tag="U2R59_001421"
     CDS             25097..25426
                     /locus_tag="U2R59_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEM8965819.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            25423..25749
                     /locus_tag="U2R59_001422"
     CDS             25423..25749
                     /locus_tag="U2R59_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965820.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            25733..26071
                     /locus_tag="U2R59_001423"
     CDS             25733..26071
                     /locus_tag="U2R59_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEM8965821.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            26071..26463
                     /locus_tag="U2R59_001424"
     CDS             26071..26463
                     /locus_tag="U2R59_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEM8965822.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            26474..26986
                     /locus_tag="U2R59_001425"
     CDS             26474..26986
                     /locus_tag="U2R59_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEM8965823.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            27032..27400
                     /locus_tag="U2R59_001426"
     CDS             27032..27400
                     /locus_tag="U2R59_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEM8965824.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            27454..27741
                     /locus_tag="U2R59_001427"
     CDS             27454..27741
                     /locus_tag="U2R59_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965825.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            27758..30877
                     /locus_tag="U2R59_001428"
     CDS             27758..30877
                     /locus_tag="U2R59_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEM8965826.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            30910..31677
                     /locus_tag="U2R59_001429"
     CDS             30910..31677
                     /locus_tag="U2R59_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEM8965827.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            31674..34505
                     /locus_tag="U2R59_001430"
     CDS             31674..34505
                     /locus_tag="U2R59_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEM8965828.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            34480..36237
                     /locus_tag="U2R59_001431"
     CDS             34480..36237
                     /locus_tag="U2R59_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEM8965829.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            36254..37036
                     /locus_tag="U2R59_001432"
     CDS             36254..37036
                     /locus_tag="U2R59_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965830.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            37036..>37777
                     /locus_tag="U2R59_001433"
     CDS             37036..>37777
                     /locus_tag="U2R59_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HEM8965831.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLK"
BASE COUNT        13249 a         6058 c         7851 g        10619 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaatttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatatcaac gattagacac gatttcgatc gtgtcttttt tgttgtatat
     3781 ttagcctaaa atgttttttg actccccttt tgactccccc tgagtactgt tcttcataaa
     3841 tgctacaaaa ttattgatga cttttttgtt ttgagtttca gttacatgag tgtaaatatt
     3901 tgaagtagtt tgaatgtctg catgccctaa acgttcctga acatctttta aagaagctcc
     3961 tgattcaaaa aggagagagg catgagtatg tcgaaaacca tgagtagtga ttcttttagt
     4021 caattctgga tgatgcttat atatgacatt aagccacgaa cgtgaaactg tagggttata
     4081 gagaagacca tcatggtgaa aaattaagtt ttccctttgg attgtaacga tcgttttgtt
     4141 ttttgtataa tactttctca ataaactgat caaatcattg tccagataaa tttttctttt
     4201 tccagatttt gatttaggag tatttacgat caatcttcct tgataacctc ttgttacagt
     4261 tttattgata ttgagtgttt tgctcttaaa gtcaatatcc gaccaggtca gagcaaaagc
     4321 ttctcctttt cttatacctg taaaagccaa tagggaaaag aataaatatc tttcatcatc
     4381 atcgtttctt attgcttcta aaaatttgat taattcttct ttagtataaa attcgatatt
     4441 tttatcttcg atatctagag cttctccacg tggaatagaa actaatttca taggattgct
     4501 agttataatt tgtaaagaag cagcgtaatc aaaaacatta gatgtgtaat tttttatttt
     4561 cttaaaaatt ttaggatggc tatcggacca agtgtttact gcttcttgac agaaaaaaac
     4621 gtctattttg tcaatgaact tatctccaaa cacttttaag atgtgtgtgt caaaaatttg
     4681 tttggtggag gaccaagtgc tttctttaac tgtcttttta taattttcaa accataagcc
     4741 gtaaacatat tcgaatttct tgctcttttg agctgtagaa gcttgcagtc ctttttcctg
     4801 tatatctgcc tccaatcttt ttaaagctct ctcagcggct aatggcgtac taaaacctcg
     4861 tctcgttgtt tttctttttt ttcctgttag aggatcaact cctaagtaca gactaaactg
     4921 atatttttct tcgccttttt ttgttaagtg ctttttaatt cgtttatcaa tttctttttt
     4981 tgccatcttt atctttcctt tcgtacgttt gttcggttgt acagcggatt tcgagatggt
     5041 aaaatagggt acaacaaata gacctacttt accgtagctc tttgcacatt tgcgttcttg
     5101 gtcgggcggc aaatgtgctt tttttatttc actcttagtt cttgtcctgg ataaagcatg
     5161 tagttgtttg gatccatacc gtttaatgca aacagttgat ctaccgtaat tccagctcgt
     5221 tcagctattt gtttggtccc ttcaccaggt tgcaaagtca aggtttcggt ttcagatgaa
     5281 gaaggtgccg ttggttgagc ttgattagct ggtacataat cttgtggtac tgattgctcc
     5341 gttgaactgg gagtgggtga aacttgttca acacttgaac taggagtagc ttctgcatag
     5401 ttttctacac tttcagcaga gtaagtacta ctagtttcag gaggcgtatt ctgcgcaata
     5461 gcagcttgtt ctacagtact agaagatgca atagtacttt ctgttgtagt cgaagatgat
     5521 tgttcgttgc tacttgttga gctagtagtt gttctagatt ctttagtttt tttccttttt
     5581 gtagggtttc aaaactaatt tctcattatc atcagatttg ttaggctttt ctggagttaa
     5641 aataatattt ttatcttctt tgctgacagt atatttggca tcattatctt tgtctttatc
     5701 atctttccaa gtcataacat cgccttcaag tgtatactca aatttgtaat tcatttggtc
     5761 gactaagctt ttagcaaatt cttctcccat agcctcccaa tcgttacttg aagttgattt
     5821 catagaactt gtgtcaacac taaaagatac gacgtgatca gaaaatgata cgatcatatt
     5881 aggttcgtca tctttggttg cttcaatcaa ccaatcatta gcttttaaat cttctgtagt
     5941 tactttttta ccacaagcag tgaaaagtaa cagagaagca aaaactaata aacttgttat
     6001 tacttttttc attttttatt cctcatttct atgatatgat ttttattggg gaatcttaga
     6061 aataaggttt cgagtccgtg ttgctgcacg ggcttttttt atttaaataa atcccaaaaa
     6121 ctgaatgtag ttttcttgta tactttattg taagcagcct tttttgggtc tttaatccag
     6181 ccgctacctt ttttcccata accaggaata actgcttttt ttacttttct ttttgctttt
     6241 ccagtggttc tagcgcttat ggattttttt atacttggtt ttctcattcc tattttcatc
     6301 tatatcctcc ttacgttgta ttataattca caagaaacga tcgaattcat ctggtaatcc
     6361 aaagcagacg agcttttcat attttgtcat atgatcaaag ccgtctaaag ttggatcaat
     6421 agtcagatga gttgcgaaat aatttgcttc tttttcaatt tttaattcag atactagcgt
     6481 ttttttagac aacataggtg tgttttcatt cggatgcaaa acacagtggc ctaattcatg
     6541 actacaagtt atccattttc ccatctcatc taaactagaa tttatgtgga tcatttttat
     6601 ctgtttgaat ttactatagt aaccataaat ttctcccaaa tcttcttcta aaactagtat
     6661 cttcaattct cgtgcaattc taaaaggatt gcgtgtttga tatagtttta ccagcttatt
     6721 aattttgtta tcaatttgag gtaaatacat aaacaacgta ctccttttaa tcgcgatatt
     6781 ttttaggtgt gtattttttc ttagcttcta ttttagctat tcgcaaagca ttctctaaag
     6841 aaataatgag agcttcacgt gtcgcttcac tcatttcatt atctttcttc gaaaaagcca
     6901 ttccatcagc attagataaa tcgtcgatta atgactgcaa ttctttttgg atatcacgct
     6961 cgtctttttc tgttaaatca tagtatcttt ttttctcagt acgtcctagc aaataatcta
     7021 cagatacgtc gaagtagtca gcaatttctt gtaacttttc ggcagttggc tgttttcctg
     7081 cgtttaaact ataaaagtaa ttctctccgt acttcaaatc tttagcgact tgttgaaggt
     7141 ttttattctt gtttttcgct agttctttta ttctttcaaa tgttgtcatt ccaacgttcc
     7201 tttccaacac gaaaaaataa tttacgaaaa agagtaaaaa tagctttaca attttacgat
     7261 atagagttat tatttatccg taagttaatt tgatagaaaa aagcaaacta aaaacacacc
     7321 ttatagcata aagtttggcg accaagtgca aataaaaggt tttgttatag gcttatttct
     7381 ctatgtattc attttactct atagtgtaaa aatgtcaatg gaaattatat tttttctatc
     7441 attttaactt acaaatttat aaaaaaagga agtgggttaa tgtcaaactt ggataacggt
     7501 cgtgcggcga tcaaagagtt tatgaaagag aatggaataa ctatggatga tttggctact
     7561 gcttatggtc acacgcgtgt acgaatgcaa caaattcttg atggacactg gagtggacca
     7621 aaggcaaaca gaactattct agagatcatc cgtgattaca gaattcgata ggaggcaagt
     7681 catgaatatt ctaagcgaag agtttttgac tcgtttaaga attgcaattg ttgaagttgt
     7741 aaaggacgca cttagtcaac tttcaaaaaa gaatttgtca gaaacacgat atttaaaaaa
     7801 gatcgaagct agaaaatatg tgggaggtgt aaacgatcaa ggttttgaga agttaatagc
     7861 tcacggttta aaagaaattc gtatagatgg ctttttaaga tatgacaaaa aggacatcga
     7921 tgaactgatg gctaaataca aaatttaaag gaggtcaaca tgggaaagtt taatcgaaca
     7981 ttagtattca gcgcgccact aattatctac gctttaggtc tatggggtag tagacaagca
     8041 ttaatcggca cgatcgttta catgctttgg attttcattg ggcttgatga agctgagtac
     8101 agagcgaaaa agccagtcgg gagggactga ctaaaaaagt ctaatgtcta taagaaaggt
     8161 ttgacaataa atgaaagaat tatttttttt aataactttc atcatttttt ctatcagtgt
     8221 tttctacatt aacctttgcg ttgctagatt tgctttgaaa agttttagga acagcaaacg
     8281 aaaatagagc tataaaagat acgaatgtag tagctacgtt aaattgctct ttagaaaacg
     8341 tcaatgtcat tggaatgata attgatatcg atgagaaaat ctttgcgata ataactatcc
     8401 atttttcaat tataaacatt tttaaattaa gcaccattag acaaaatgta gttcctatat
     8461 agaggataaa tgaagataga aataaacata ttagtccagt tttaaaaaaa gagaagtaat
     8521 ctatgtgggc aaattctgtt aatatgcttt tttgatttaa cacaatcaaa ctactgttgg
     8581 acaaaaatga cagtaaggaa agagttgctc cgattactaa ataaaaaata gttgttaaca
     8641 atattatatt atcaattttt ctgctcatgt tttcacccca ccagaattat atcaaaaagg
     8701 agagaagaaa taatgcaaga attagtaatt ttgaaaaata aagaagctgt gactacgagc
     8761 ttacaagttg cagaaagctt cgataaaaag cacagacatg ttttgacggc tattgatgaa
     8821 ctaaaagagg gggttgccga aaattgggca gacctatttt gggaagatac ttatgttcat
     8881 cctcaaaata aacaatcata ccgaattatt tatatgaata gagacggctt ctctctatta
     8941 gcaatgggct tcactggtaa gaaagcttta agttttaaac ttcaatatat tgaggccttc
     9001 aacaagatgg aaaaagaatt aaaagaccaa ttgccatcaa ttccagcaac taaacgagaa
     9061 atggcattac ttgctctagc tgcaaacgaa gaaacgaatg aaagagtaga cgctatcgag
     9121 tctgatttaa acgatttgaa gaacaatcaa cttctagctg aaccagatta ccgaacaatt
     9181 tctaatatgg ttcgcaacaa aattagagtt atttgtaatc agcagcattt aaatagcaaa
     9241 gcaaaagcag aattgtttaa agacttgaat ggcggaatta agcgaatcac tggagcagta
     9301 gctagaaatc gtatcaaggc aaaacagttc gatgatgtta tcgattttat taacaattgg
     9361 atgccttcta cagcgacgat gacaattatt aagcaaatgg agttgttaga ggatgaatag
     9421 agctgaagcg ctaaaaatag gcgtaataat tgctaatcgc tggtggagac acaataaacc
     9481 aaacatccta agccaacaac atattgataa gcaaaaagca tggcaacaaa taaaaaagtg
     9541 actcagccga ccaaagcaat gagtcacaaa gaaaatacat ctaaggagat gttaccacat
     9601 gaaaaaagaa ctttccactc tagatcaata tttgactgat cctagttggg gcaaatcgaa
     9661 tatcaaggaa acaagcaatc gaaaaatcag acgtaatctt ttgacggatg aagaactagc
     9721 atgtgatcaa gacgatttgg gaaattttgt gagtatttgg gatcatgtct atcttatcca
     9781 tttatcgagg aagtccaaaa aaactgaata tatctatgtc atcgaagatg gcttgattga
     9841 tgcgctagaa gagtatgaca gagataactt gattgatatc tcttattacg gatcaggtaa
     9901 gaaatacatt gctgaaatgg aggcagaatt tgatgagtga aaaggaacaa cctttgaaaa
     9961 atagaagtga taatacgctt tttaatacct tatacaaaat aaatgtgaaa gatgttactg
    10021 aaaaacgaaa taacctcact tatctttcgt gggcatgggc ttgggcagaa gttagcaaag
    10081 tgtgtgaggc agtagattat gaaatctatc atgatccaga aacatatctg ccgtatgtct
    10141 ttgataagaa aacaggctat atggttttta ccagtatcac agtcaacgga gtaaagcgtg
    10201 acatgtggtt accagtcatg gatggtgcaa acaaggcaat gaaagatgag ccatatacct
    10261 acgaagtcaa tgattatcag tggaataacg aaacgaagaa aaaagagatt gttggaaaaa
    10321 tcgaaaagcg agttgaagca gcaactatgt ttgatatcaa caaaacgatc atgcgctgtc
    10381 ttgtaaaaaa tctagcaatg tttgggctag ggctatatat atttgctggc gaagatatgc
    10441 cagaagatgt ctcgatgctt gaaccagcta ctcaaagaag caaaaagcta ttcttggatg
    10501 ctttacaact ggttgctaac aagtacgaaa aatcaattga tgaagcaatt gttgcattga
    10561 ctgatgcggc ttctataacc gctgatgaca gtaaatggac caagagagac ttgggcattc
    10621 taaaacgagg cgttaactgg attgaagatc agtacagaga agaaacaaaa gagaagtgat
    10681 atgagtgttt aaaccattga tcgattcata ttcagcggtt ctgaaaaagt tcaaaggaaa
    10741 agacataggt gcaacgatca atgaagaagt gaacattgat cgactaaaga cgatgtatga
    10801 cggatatgat ggcgatcgga ttattgaagt tcgatttatt gatccacgtc gatttactgt
    10861 gcagcaacga aacttcatct atgcgctgat aggcgatatt ttcatcgata caggcatgcc
    10921 aacggacttc tggaaggaat tcttttactt ccgttttgaa ggcgtcacag ggcgcaaaat
    10981 aagcctcaaa gacgaatcga atacaactgt gagtgatgct aatgtcttag caaatatcat
    11041 cttagatttc atctttgaac atcatattcc tttcaaagaa ggctatgaga ttttaccagc
    11101 gaatcaagaa tattacttct acaaatgcat cacaaaaaga gtctgctgca tctgtggcaa
    11161 aacaggagct gacatcgatc actttgacaa agcgctagga agacgaaagc gcaaagaagt
    11221 tgatcattca gagtacacat ttgcagcact ctgcaggatt catcacacgg agaaacacaa
    11281 tataggtgtg atcaatttca aaaataaata tcaaatcaaa gggatcaagt taaaccagga
    11341 aacaattaag aaacttagaa taggagggta aaaaatattg tctgacaaca aacgctacta
    11401 ctatttaaaa ctaaaagaga attttttcga tagtgacgag atggttctct tagaaagtat
    11461 gccagatggc tatatttatt ctaatattct tctcaaactt tatttaagaa gtctaaaaca
    11521 cgaaggtaag ttgatgttta atgacaggat tccatttaac tctacaatgc tcgcaactat
    11581 tacaagacat tctgtaggag tcgtagaaaa agcggtacaa attttccgtg atttgcagct
    11641 tattgacgta ttagataacg gagcaattta tatgtctgat atacaaagtt tcattggaaa
    11701 atcctcaact gaagcagata gaaaaagaga atacagaaag aaaatagaag aggcaaaacg
    11761 gaatttaata actggaggac aagtgtcgga caaatgtcca gacaaaacta caccagagtt
    11821 agagatagag atagagaaag atatagatat agataaagaa gaaaagaaag gtaagtattc
    11881 tgacgaacac ttacgccttg ctaaaaaatt gcaaagtaat ttaactgaag attttccaaa
    11941 agaaatgaac aaagtagata tcgaaaaatg ggcagacaca atcaggttga tggaagaaag
    12001 agataaagcg tctatagaag cgattgagta tgtgatcaat tggctaccta caaatgaatt
    12061 ttggtttgga aatattagaa gtgctaagaa attgagagaa aaatttgaga agctcaaatt
    12121 cgaaatcaaa gcagacaaga ataatcataa aaagcaaagt caaaaactac agtacagcaa
    12181 tcctagtgaa tatgacgact tgccaattta aaaaggagat gcatcacatg gaaagcctag
    12241 caaatgctat ggagaaacta ataagaagag tattagtgca aagcgggaaa tgtccagaat
    12301 gtagcgaacc tttgtatagt tggcgagcta aaaataagga tggttcagaa cgttgtaaac
    12361 caacatgcat gagttgtggt tataaagcgt tacgtgtgaa agaggatata cagaccgaac
    12421 ggatatataa cgacagctta aaagcacgag cgttgagttt ttttcaaaat ggttcggtat
    12481 taacagataa aactttgttt aaatgcaaaa tggagaatta tcacgtagtg gaccaagaaa
    12541 cgaaaattgc tttagaaaga gctaaaagct ttgtaaatga tgtcttactg aaccatcctg
    12601 cacatttcat tctatcaggg aaatcaggaa gcggaaaaag ccacttgtca atggcgacag
    12661 cttgggaaat acttgagcgc tcaaattatg acaagaaaat actttttata agctatcaag
    12721 agttattaga gcaaataaag ttttcttata acaatgctga actgagaaaa gaaattgaag
    12781 gatcgcttat agccgatatc aaaacaactg atttggtggt ttttgacgat attggagctg
    12841 aattaggtag cggggtatca aatagtaggc agtttacaaa caacacgtta aacacgctct
    12901 tagaagccag acagaacaag gcaacgatca tcacaacaaa cttatccggt cctgaactaa
    12961 gagaagccta cggcgaaaga attgtttcta gaatatttaa gaattcagaa ggttatgcgc
    13021 tgaaattcca acaaacagca gacaagcgca taaaaccagt gaaaggtagt atcgcatgaa
    13081 taaataccgt aataagaaaa ctgttcatcg aggtatcaag tttgattcta tcgcggaagc
    13141 agagtattac gatttagcct tgtggcaagc agaagcgaac ggctggaaag taaaacttca
    13201 ggaaagattt gagctgatgc cgaaatttga actagatgga aaaaagtatc gcaagatcga
    13261 gtatattccc gacttcacat tttataaaaa cggcaaactt gtcaaagtcg tagatgtcaa
    13321 aggaatgcag acaaaagact ttaagatcaa ggcaaagttg ttctgtcatc aatatcaagt
    13381 gccgttgata ttagctaaaa aatatcggaa tacgttcaag gaagagcgtt tttaacgagg
    13441 tggtccatca tgacaacaga agaagtgatt caaatgcgta ttcgaagcct tcaacgtgag
    13501 attgacgatc tggaacggat aaaggcagtg atggtcaatg aaacggcgag aaaggcaatc
    13561 aatttgcaca tagtgaattt aagaagggaa attcgtagat tggaggaatg agcgtgggta
    13621 agaaagcagc aatgaaacga atcattgaac tgacacattc tgagaattgg caagaagaca
    13681 aagaaatagt tgcagaagtc caaaagctcg gtaaatcaat gtggactgaa aagcctaaac
    13741 ggaaaacgcc gagaaaaatt gcaatctggc atggtgatcg aattctagta acgggtacag
    13801 ctgaacagtt atctgaaatt actggactga gcaaaaacat catctgggat agagctagga
    13861 gcttatggat tgattcaaag gggcgacagt ttaggtatgt ggaggagaaa taatggatct
    13921 cattacacaa tacagtgata tcatcctcaa gaaaatcatg atgaagattc agaaagataa
    13981 aaaagcaaaa gaacgagcgg aattagttaa gttggaaatg gctgaaacag gagcaggagt
    14041 gcgaagtagc aggcattgga aagcagcagc aaacattgaa ttttattaca acgaaattca
    14101 aaaagggttc gatcagatgc gtgagctgga tcggcaaaca aattggagca agaaacttca
    14161 tcaggatcgt ttcaaatttg tagaaaagta tagagagata ctgaatgagt atttcgagga
    14221 ggactagatg tttaattcaa cgttagcgtc aattcacttt ttattctata taacgatatt
    14281 tgtagctata ttaattaatg cgataaaaag cggtttttta acaccaatcg gcacaatttt
    14341 aacattagct tcatttgtta caagttgtat tatccaactt aaatatataa aggagaatga
    14401 ataatggacg aactaatcac aaaagtagag cagtgggcta aagataaggg attggatcaa
    14461 gctgattcca gcaagcaaat gttaaaaacg atcgaagaga tcggggaagt tgccgcttct
    14521 ctagctagaa aagatgaaca tggtttaaga gacggaattg gagatgtagt agtaaccttg
    14581 attattttag ctatgcaaaa tgatatggat ttgtacgagt gtctgaacca agcatacaac
    14641 gaaatcaaag gacgcacagg aaaaatggta gatggtgtat tcgtgaagtc gagtgatttg
    14701 gaggacagca aatgatcagc ctaacaatat tttggtgtgt aattggcggc ttactagcga
    14761 tgttaggagc atacctcatt tacgagagtg caaaaggcaa aaaatataca gcagtaggga
    14821 ttattttgtt tgttgtcgga attttagttg cgattggtgc agaaataaat ctttatttaa
    14881 acggtacgac agaagagttg atgtggtttt tattgtggac aaggagatag gaggacagcg
    14941 aaatgggcga tatgggcgaa tactggaaag atattaaacc gcatctaaaa gaacgtagaa
    15001 aacaacatgt cagaaagatg ggcaattcag caactaaaaa tattgaaacc ttgggatttg
    15061 aatttactca ttatccaaac aatcatcaat ttgcaattaa tacccataat ggaattattg
    15121 actactgggg aactacagga acgtggattg agcgcaaaac aaaaaaacgt ggtaaaggga
    15181 tacgtagttt gaggaaatat attaatcagg aggacagcaa atgaactata cacaacaaga
    15241 actgactgat ttatgtccaa aacatgtagc tgagttcatc aataatgaag tcctgcctaa
    15301 atatgcagat ggtttaaata cagcagaaaa cgttacagat tttatgatta atgatgctat
    15361 tgatcgtttg atatttttag aaatagattg tattgcttat tatcgtctac acgcagaagt
    15421 tgctttgatt gatccgtata ttgctttaag ccaaaatcga aaaatactcg tagcctatat
    15481 tgataccaaa cagattttag aaggcagaga tgtcgagata gagatcgatg aggaggaagt
    15541 gggatgaaag catacacaat caagttttat ggaaataaaa cctatgtata catcctaagc
    15601 ggtctcagac ttgattttag aggctattca aaagaagacc ttttagaatc cttatatggt
    15661 tacggatatt taaatgaaga tgaactaata agcttagaga aatttacaaa tgcttggacg
    15721 attgaggagg aagcagaatg aagatttatg tagtaaagtt cgggaataaa ttttatagaa
    15781 gtgatgaacg ctctataggg gctaacacat tattcattgt agacatactc caaagtgcga
    15841 gatggtttga tagcctcgaa gaagctaacc aagtttcacg acgacttggt ggattaacac
    15901 aagtatatga actggtcact gtcgatcatg aggaggtaga aagatgaaat taaaagacgg
    15961 attttacgct agtagtcatg gtatcggcgg tttaatgcta gatatgccga caaagaatcc
    16021 taaaaaacgt aagaaaccaa aattcaaagt cggtgacatg gttcgctgcg aagcagaagg
    16081 gttcatctat ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg
    16141 tattgaaaac acgatggaat gtgataagtg gttagcgaaa agcaaagaga atttagctgt
    16201 agcgagattg gtggatatga aggctatata aacagcgaaa aaatgtactt ctaagagaaa
    16261 aatttatttt ttataaaaat aggaaagtat cattatgaaa aagaccacag agataaataa
    16321 acctaccaca taaaaaatga atatttcttg cgattcaata taggtatatt taacaatttg
    16381 tacaataaaa aatactatag gtaaaaaaga taacatgagg agcttatttg ttctagagtg
    16441 tttgacaaag taacaaaatg cgacgatacc aatacaaacg ggaatccaaa ataacagcat
    16501 gctccacata gtcactcaac catctcctat acgctttatt atcaatagat aatatcattt
    16561 ttcgtaataa agataaaaaa ataagtaagg cttctcatta aaatataaaa aagacagccg
    16621 accactggct gtccttagca gaatattgaa atagtgagcc atctgttttc cgccagatag
    16681 ctcaacatgt atatgggtaa cgagtgcaac ctcgctactt gaaaagctta gcataagcat
    16741 gggtataaaa aaagccggat tcctccgacc ttaattaata attctgacac aattattata
    16801 tcataaatgg aggaatcaat ggatggtact tttcgatgta aagaagtatg agacaccaga
    16861 ggcaaaagat gtggatatgg atcgcacaaa acataatgtt ggtgtttttc tttcagcata
    16921 tctgtcagct agatgtagga taggtcaacc tcgggagcct aaagtaacgg catcttactc
    16981 cttggttcca ccttctacag caaataatac atttgaagca gaacgaatga tgattgagag
    17041 aggaagcgca agaagaattt gagtacttgc acaaattatt tgttcgtggc tattcagcaa
    17101 ttcagcatcc gcataaacct gatgtaacag aaaggcgcaa gaagatattc tatgatcgtt
    17161 atatcaatgg tctgcccatt tatgtaactg ctcaaaggaa taatactagc gaagaatcgg
    17221 ttaaagtaga atcaaacaga attatcatcc aatttgcttc atcgttagaa ctggttgctt
    17281 ttaagtagcc agtttttaca ctttttatac cctttgatta cccatttggt ttccatttta
    17341 tacctttttt ataccaatca cttacctggt aaatgattta ttatgatagt gtcgaaagat
    17401 tagtgatagg tctgagacaa aataataata aaaggaacat cgttttatta ttgtttcaca
    17461 attaagcttc gatagacagc aacggaaata ttaagaataa ggatgtgaat tccaactcct
    17521 tctaaattgt tcttattatc tatcatccgt tgctgtttat taatttatgt attggaggga
    17581 aaacgaatgg aagtcgagca aataaagtat caaggtatgg atcgggaacg gttgattgat
    17641 attattgagc aacaacgttt agaattgatc caaaaagaag ctgtatgtaa agagtacaaa
    17701 aaacatttag aacaagtaat tgagtatcat tcagtagaaa agtacagatc agtggtgcaa
    17761 aaaaatagag caacgagtcc tgatcctcgt caagatgtat cgattagtat caagacgcca
    17821 gtatttaatt ctgttaaatc agaaaagcta gaaagtatct caactgcttt ggtagaaaaa
    17881 gcagctgaaa tgaactccct agcaaatgaa gttagtcgtc ttatttagtc acatcgataa
    17941 cttgagagtc tttggtgatt ccgtttttta tagaattaat ggtttgttca gcggaatatt
    18001 tagtcaagta tgtttcgcta gttgctacta cttcattgtt atcggactta ataacgaagt
    18061 aatattggcc attagttgct tctcttataa caaagtacaa atttttcacc accttttaat
    18121 ttatttcagc ggaccactcg ctgataaata aaattataca cttagtattt attttcacaa
    18181 tattaatttg tcactgtggc ggaaagggta gacgctaagc atgtgtgtta ggtcaatgct
    18241 tcggcaacca tgcaaggttc gattccttgc cagtgacttt ggcaactgag ggttggaaat
    18301 gggcgctcaa agtacacgag caaggcgagg tcgatagtaa tcgatggaat cggtgtaggt
    18361 tgcttgatag aactataact gcatctcgtt tatgaggtgt agtttttaca tattagatca
    18421 ctcatcgagt ggtcttttta ttttggaagg ggagtaaaaa aatgaacgaa aaccaattaa
    18481 gagagttgtt taaaacgaat gaagcaaaca aaacaatgga ggcgacattc tacgaaactc
    18541 aaaaaagctt agcgttaatc gcaaaacaag ctaagtattt ctacgatcag cttattctgc
    18601 aaggatttaa tgacgcacag gctatggaat ttatgatgcg aaccttttct gccagtaacc
    18661 aacagaaaga gtgatacgta atgaggaact actggtatgt atcattatca aataaatatc
    18721 cgcaaccaaa cgcagatgat ccaattagag ttgtccagtc agtccagatt aaaaagaagt
    18781 actccatcat tgaaatgacc agagaagcta cgccaaaaga gattgataag tacaatcttc
    18841 gttactgcgg ccatggatat tttagtgagc agaacataca gacaaatatt gagagatatt
    18901 gttaataaaa ttgaaaggtg gtggcttgaa tgtggtaaat ttgacaccaa aacaaaaagc
    18961 ttttgcggat gaatatataa aaaatggtgg taatgctact caagccgcca ttaaagcagg
    19021 ttatagcaaa cgatcagcaa gagtaatagg taaggaaaac ctaactaaac ctaacataat
    19081 acagtatatt aatgaacggc taaatcctat cgaaaagaag cgcaaattaa gtgccgagga
    19141 cgctttaaat gaattgatag atatttggca aggagaagta caaataagcg tgagcaagca
    19201 aatagaccgc ttggagaaaa acaaggttat taaacatatg caatatgaat atacaccaga
    19261 tttagaaagc aaattgaaag ccttggattt gtatttgaag tataaatcgc tgttatcaca
    19321 aacgcaatta gaaaaagctc aaacagaaat aaaattaatg caagcaaaat tagaacaatt
    19381 acagataaac tcagagcgtt ctaccgaaga aaaacttgat gagttgttag aaaagattag
    19441 tggtgaatta gatggcacta gttgatattt ataacccaaa gcaaatcgac gtgttaaata
    19501 aaaccattaa gaatgattgg tttattactt tattacatgg agcaaaacgt tctggaaaaa
    19561 caaaaataaa caatgatttg ttcttgtttg aattgcgacg tgtgcgaaag attgccgatg
    19621 aagaagacat taaggaacca atgtatatcc tagcaggagt ttcaagtgca acaatccaaa
    19681 agaacatctt acaggaacta tacaacatgt acagcataga acctaaattc gataaacatg
    19741 gaaactttaa gctatttggc gttaaggtcg tacaagctta tacaggaaac attggcggtg
    19801 ttggcgcaat tcgtggtatg acagcatatg gcgcttatat caatgaggca tcgctagcta
    19861 gacaagaagt atttgctgaa atcgtttcac gttgttcagg aacaggagcg agaatactag
    19921 ctgatacaaa ccctgacaac ccggaacact ggctaaagaa agagtatatc gacaattcaa
    19981 gcaaaaatat tcaatcgttc cactttgaat tagatgataa tacattttta tctgaacgat
    20041 atcgtaacaa tattaaagaa tcaacaccaa gcggcatgtt ttatgatcgt gatatcaaag
    20101 gtttatgggt ttctgcagaa ggtgtcgttt atcgtgattt tgatgctagc aagcactaca
    20161 tccagtcaaa agacttacca cctttgagca acttttattg tggtgttgac tggggatatg
    20221 aacactgggg ttcaatcgta gttataggtg aaacggatga cggaacagct tatttaatcg
    20281 aagaacatgc tactcaattt gaagagattg attattgggt agatgtggca aaaggcattc
    20341 aagagcgtta cggcttacga gtaccttttt attgtgactc tgcgagaccg gagcatgtgg
    20401 ctaggtttgt aagagaaaag attaatgcta aaaatgctca taaagcacgg ttatctggag
    20461 ttgaggaagt cgccaagaga tttaaacaag ataaattgtt tatctgtcaa gatagagtga
    20521 tgaaatttcg ggatgaaatt tatcaataca tttgggacaa gaaaaaaggc gagccaataa
    20581 aagaatatga tgatgtgcta gactccgttc gatatgcgat atatactcat gagcttctta
    20641 agaaaccaaa agttaatgtc aacgaaaaga ttaaacgtat taaacgcatg ttttaaggag
    20701 tgtgaaaaat ggataaggta aacgagtttg aatacggagc tgatatacat tattctaatg
    20761 acgtgaacac aaattatgta aagtttagcg tagactcaaa tcttcactat agatttagct
    20821 cagcagaaga tttacttaac gatttagata ctttagcagc aatgataaaa catcatcatg
    20881 aatatcaggt aaaaaggcta agtgtattag atgattatta taaagctaga aatacaaata
    20941 tcatggataa ccgtaggcgc agagaaaaag aaaaagcgga tcaccgatca gcacataact
    21001 ttggaaaagt tctttgtacg tttgatgttg ggtacaacac aggcaatcct ataaaagtgc
    21061 aaatcgagga cacaaatcaa caaaaagaaa tcgaagagtt taatactaat aatgacatag
    21121 atgggttaaa tgctgaactc tggcttgata tggataagta tgggagagcc tatgagatta
    21181 tctatcgaga ttcagatgat acagattatg ttgatttggc taatgtattt gaaacgtttg
    21241 ttgtatatga tactacagta aaacgagagc ctattttggc tgtacggtat cctaagacaa
    21301 gattcaacaa ggatgctgat aaacagtaca ttcaaccaat cgtatacaca aaagaaaaaa
    21361 gtatcactta tgatgagacg acactaacag caattgagtt aaagaatccc caggatgaac
    21421 cgcatgaata taaagaggta cctattacag agtattctcc taatcgtttt cggatgggct
    21481 tgtatgaaga tgtactatct ttgattgatc tatacgatgc agggcagtct gataccgcca
    21541 attatatgac tgatctaaac gatgctcttc tagttattag tggtgatatt gaagcagcag
    21601 gactatccac agaggacgcc atcaagcaga aagaagcgaa tatgcttttg cttgagtctg
    21661 gaactgatgt gaacggtaat aaaacaagtg tgactgcagg atatatttac aaacaatatg
    21721 atgtgaacgg tgtagaagca tacaaataca gagtacgcaa ggatattcac gaaatatcca
    21781 tggttcctga tcttactgat gacaattttt ccggagtgca atcgggagaa gcaatgaaat
    21841 ataaattatt tggatttgaa caaatgacgg caacaaagca aaggctattc aaaaaaggcc
    21901 ttatgcggcg ttatcgtctt ttatttagcc taaaatcaag tatttctgaa atggataact
    21961 ccgatttgaa aggcttacgt gtaatattta cgcctaatct acctaaagcc attctggaag
    22021 agttgaaatc tttggttgat gctggagctg aactcagtca agagacgatc ttaggactcg
    22081 cttcttttgt tccagatgta caggcagagt tgaaacgagt aaataaagaa acgcaaaagc
    22141 agattggcat ttttgattca gatggtgaag aagtaattaa caacaaaaaa gatgaaacag
    22201 gggggtgatt aaatgaactc ccaagaatat tggatcaaac gggaaaagga atggcaaaag
    22261 caacaaatta aagatgataa aaagcgcatg gcagaaatta aaagtcgcat gcaatacgca
    22321 caagatgcga tacaaaaaga aatagacgcg cagtgggaca gtttctccaa tggccagaaa
    22381 atcactcgta gcgaagcgat gaagcgtgct agtgaaatgg atgtcaaagc attcgctcgc
    22441 aaagcaaaga agtatgtcaa agagaaagat ttttctccta cagcaaacca agaattaaag
    22501 ctatacaatc ttacgatgcg tgtaaataga ttagagctct taaaagctaa tatcgggctt
    22561 gaattgattt cactgtttaa tgaattggat aagtactttt cgaatgaatt aacaaaagct
    22621 ggtttagctg aattgaagag acaagccggt attttagaaa tgactattgc ttcaagtgga
    22681 tatgcaaagc tgatagaact agtaataaac agctcctttt tgagtgatga cgtgtctttt
    22741 agtgatcgct tatggatgta tcaatctgaa ttgaaatcag aattagatag gttgttagtc
    22801 agaagtataa cgatggggaa aaatcccaag caacttgcat ctaaattggc agaatattta
    22861 acagctgaag gacgagaaaa cactaagttc aacactcaac gtttgatggt gactgaaacg
    22921 actagagttc aggtagggat tcaagaacga agttatagag atgcaggcat tacccagtac
    22981 atctatatag cagaaccaac ggcgtgcaaa ctatgtatac cgttaaataa tcaagttttt
    23041 gatgttgccg atatgcagcc aggaagtaac gctcctaata tgcatccatt ttgtcgatgc
    23101 agtacagcac cttatataga acgaatatca agccgttaac acaaattaac ggctttttat
    23161 tgtgccttct tacagcttac aggcgttaaa gagaaagcta ttttcggctg accggcgtaa
    23221 ctggtcaaat ttatcgggta gcggcgtaac cgtggaggat taatcatgaa aaaacgttta
    23281 tttatgccaa tgaacttaca atttttttct gaaccaggag atggtggatc tggtgatgag
    23341 ggacaacaag gaaacctacc agctggctca caagagacac cgcccgaagc aaaagaagaa
    23401 aacaatactg gcaaaacatt ttctcgtgat gaagtagcga aaatgatcgc tgctgagacg
    23461 aataaagcaa aagcagcgtg ggaaaaagaa ctagcagcaa aaaaagaaga agctaaaaag
    23521 ctggcaaaaa tgaatgcgga agaaaaacta cagcatgagt tggagcaaaa agaagctgaa
    23581 atcgctgaat taaagcgtgg acaggcacta tctgaaatga cgaaagaagc ttctaaaatg
    23641 ctgacagatg caaatttacc acacgatgat gatttacttg gtctgattgt ttctgatgat
    23701 gcagatgcca caaaacaagc tgtagcagtc atcactaact ttgcttcttt gattaagaga
    23761 gaaaacgcaa gacaaacacc accaaatgaa ggtggacaat ttacagcatc gaaaaatact
    23821 aaagaaacag tggctaaact agctgctaaa aatcgaatta tcaaatagga ggaaaactta
    23881 atgaaaaaga aacaactttt accaatgaac ttgcaaatgt ttgctcaaac atgggatcca
    23941 gataatgtct tggtatatga aacgaaagag ggaaaaattc ctgataaata taatacgctc
    24001 attttgagtg aagttatgga aaattctaag atcatgcagt tagcaaaata cgaagaaatg
    24061 actgacaaag aaaagaaatt tgaatacttt gcagaaggac caggcgcata ctgggtgggt
    24121 gaaggtgaaa aaattaaaac gtctaaacct aaatggatgc aagctacgat gactgcaaaa
    24181 aaactcggtg tcattcttcc ggtttctcgt gaatatttaa attataaatt atcagatttc
    24241 tttgaggaga tgcagccaaa aattgctgaa gctttctata aaaaatttga tgcagctgcc
    24301 ttattaaata aagaaaaccc atttcctcag tcactagacg gatcagttat tagtgcgggg
    24361 aatgtggttg aaggcggatt gacttatgat aatatcctag ccttagaaga caagttagca
    24421 gaaaatgaat tcgaacctaa tgcgtttatt tcaaaccgaa aaaatcgtac agaattacgt
    24481 tctgcagctc aaacagtcgg gtcaaatgtt gagtttattt atgatcgctc tactaataca
    24541 attgacggat taccagtagt agaccttaag tctttagata aaggaacact ttacgctgga
    24601 gactttaatt acatgtttta tgggatccca tataatattt catttaagat ttctgaagaa
    24661 gcccaattgt ctactttaac taatgaagat ggaaccccag ttaacttgtt tgagcaagaa
    24721 ctgattgctt tgcgtgcaac aatggatgtt ggatttatga ttgtaaaaga tgaagcattt
    24781 gggaagattt ccccaaaagc gtaacgcctg ctaccggtat tgtgccaaat caaaagacat
    24841 ggaccggtaa agtaggcgat actaaaacat ttactatttc agctgtgcct gcagatgcta
    24901 gcgatgcagc tgctgttgtt gcagctacta cagcaacttc aagtgatgga gctatcgcaa
    24961 cagtgaccaa aaatgaaaat ggtggttttg atggaacgat tgcagcagaa gggtcagcaa
    25021 cattcacatt tacttctgga gaattcacta cttcaatcaa tgtgacaggt caacctgcta
    25081 gttaggaagt aaaaatatga tgattgcaga tgatattaaa aaacttctta aaggaacaat
    25141 agatgaaaag cttgaagtta ttgagcgaag aacgaatgag cgtatgaaaa ccttgttaaa
    25201 tacgcaagaa gttcctaaag aatttgaaac agttgtatat gaagtatcgt tgaaaagatt
    25261 caatagaatt ggtcaagaag gtatgcagtc atattctcaa gaaggtttat ctatggcttt
    25321 tcctgactcg gatttttcag agtatcaaaa tgagattgat gaatttaagc gtaaagatca
    25381 ggaagagttg tacaagccaa agcgagggag gtttaaattt gtatgagatt tacagatgaa
    25441 attatatttg ttaaacgttc atctgactct aaatatgatc cagatctcgg tgagtgggtt
    25501 gaaggcaaac cagaaagaac aagaacagag gcaaacgtga cagatattgg cactgataga
    25561 agtgtgacta tttttggtag tgtggaagaa ggggcgaagg tcattaggac gcagcctctt
    25621 ttttctatcc ctacatttga ctatatcgag attgaaggaa agacttggca acaaaaaaca
    25681 gctagaaatc cagcatatag aaatagttta attgtgcaag aggtggttct tgatgaaggc
    25741 acaacttgaa tataaaggaa tcgatcagct gatgcgacat ctgaaaaaag cagcaacgct
    25801 taatgacgtt caaaaagtcg tgaaaagtaa tactgctgaa atgactgaac gaatgcaaaa
    25861 aggtgcgcca gtggatacag gttacttacg aagatcaata aacatgaatc ttttagaagc
    25921 tggtttaact ggtattgtag gaccgacagc agattatgca ccttatgtag aatatggcac
    25981 tcgatttatg tcggcacagc cttatgttag accagcgttt aattaccaaa aagtcaaatt
    26041 tatggctgaa atgaaagcct tggtgaaatg atgattaaga caagagatca atcaattttt
    26101 gatgaacttt ttaaaatatc ccaaaacaaa cttggatata aaacatacga ttacaaaact
    26161 ttagaggatg ttggttatcc ttttgtggaa tttgagaaca ctcagacaat ccatgaagta
    26221 aataaaactg acattaaagg gtctgtgatt gtggttttat ccgtttgggg attacagaag
    26281 aaacgaaagc agttgtcaga tatggcatct gctcttttta atgaagctag attgatagaa
    26341 gccacagaag gctattattg ggctttaaat tatcaagcaa gtggaattca agtgatggac
    26401 gacacaacaa cgaatacacc gctaaaacgg gcggttgtca cacttgaatt tagaattaga
    26461 taggaggaag aacatggaag cattaaaagg tattgatgtc attttgcttt atcgcttatt
    26521 gaaaaaagaa actcaggaag ccgcttggaa aatggcattt caaacagaac acgaaaatgg
    26581 tttatcaaga gattcagact ctacagtgac aaaagatgga aacgttcaaa gtttaagccc
    26641 ggttgaatat gatttttcgg ctacttcaat agttgctaaa ggagattctc atgtagatga
    26701 aatgaaacaa gctttattaa atggggatat cattgaaatt tgggaaatta ataaagcaga
    26761 acagggaaca gatgataatg caaataagta caaagctact tattaccaag catatgtgtc
    26821 tgaatttact ccatcggctg ctgcagagga taacgttgaa ttaagtttat catttgcagt
    26881 aaatggtgtt ggtcaagatg gttatgcaac cttgacagaa gatcaagccg atgttgttca
    26941 atatgcattc aaagataccg tgaaagcaac ttcgacagga gcataagagg gcttagatgc
    27001 tctctttttt attttaggag gatgaaaaac attgaaatta aaaattaaag gtaaagaata
    27061 ttcgtttaaa tttggcacta aatttgtacg tgaattagat aaagtgatgc ctttcgtcga
    27121 tggaaatatg gaatttggaa tgggactctc cgcaaaagtc ttaccagagc tacgttctta
    27181 taacgttaac acgttatcac gagttctgga aatagcaaat agaactgaag atgaatctat
    27241 tacattagat gaattggatg attacatcga tgaagttaaa gacattgaaa aattgtttga
    27301 tgaagtccta aaagaattgg cggagtcgaa cgcgggaaag ttagcggtcc gaaacctgaa
    27361 tcagaaattg aaagaagcgg aaaaacaaca agtggaatag attctgcact ggcatacgaa
    27421 caaattctta tcaattcttt tcgatatttg ggaatgacca atatctcaga tatcgaaaga
    27481 atgacgttat atgaatacaa cattcgtatg actgcagccc agttatcttg gcttgacaaa
    27541 gaaaagttga ttcacgaatt agcgtgggca aatcagcaag tccaagcgga gaaaaaagta
    27601 ggcaaaaaga cagttcctgt atatcgatcc tttgaagaat tcttcaatta tcaaaaaatc
    27661 gaagattcaa tcatgggagt ttccgaactt tcaaaacaag ataaaaaatt ccaaagctta
    27721 ctaactaaag ctaactcttg aggaaaggag gagaatcatg gaacaatttt ctgttgaagc
    27781 cttattaaaa gccacagata gtggatttgt aaagactttt aaagatgcac aagatgctgt
    27841 taaaactttt gaaaagaatt caaatagtat gacaaccgct gttggtaaag tgatgcaagg
    27901 tactggtgcc gcaatgacaa agtatattac cactcctctt ataggagtag gcgtagcagc
    27961 tgctaaagtt ggtggcgact tcgaagcaca aatgagtcgt gtaaaagcta tatcaggagc
    28021 aaccggcgac acattcgaac agatgaaaca gcaagcgatt gatctaggag caaaaactgc
    28081 ttttagcgca aaagaatcag ctgctggaat ggaaaactta gcttctgctg gatttagcgc
    28141 acaagaaatc atgaaagcaa tgccgggtct tttagactta gcagctgtat ctggagggga
    28201 tgtggctcta gcttctgaaa atactgctac tgctttgaga ggatttggtt tagaagcaag
    28261 tgaagcagga catgtcgctg atgtatttgc tcgtgctgct gcggatacca atgctgaagt
    28321 tggagacatg ggagaagcat tgaagtatgt tgctcctgta gctaattcaa tggggatttc
    28381 tttggaagaa actgcagcag ctattggtat tatgagtgac gcaggcatta agggttctca
    28441 agcaggtaca acgttgcgag gagcattgtc taggttagca aggccaacaa aggctatgca
    28501 agatacaatg gataatttag gtgtttcgtt ttatgatgct gacggtaaaa tgaaaccttt
    28561 aaaaactcaa gtagaattac ttaaaaaagc ttttgaaggc ctgacgcctg aacaacaaca
    28621 aaatgcttta gtaacactat atgggcaaga atcattatca gggatgatgg ctttgattga
    28681 taaaggacct gattcattgg gcaaattaac aaaatctctg aaagattctg atggtgcagc
    28741 tgacgatatg gctcggacca tgcaagataa tatgaattct tccatcgagc aaatgtttgg
    28801 agcttttgag tcagcagcta ttgtaattca aaagattcta gcaccatcca tcaaaaaagt
    28861 agcagatgcc atatccggct tagtagaaaa atttgtaagt gctccagaat caactcaaaa
    28921 attagtagtg gccataggag caattgtcgc tgctatagga ccgttaattt ttatgattgg
    28981 ttcagtaatt atatggatca atagggtgaa agtagctttt aaagctttaa gtgaaagttc
    29041 aaaattgttt agtggattaa gtaaagcaat gggtcttctt acaaatccgg tttttctggt
    29101 tatagctgcg gtagcactac tcgttgtagg tttcatctat ctttggaata cgagtgaaga
    29161 ttttagaaac ttttggattg gcttatggga gggaatcaag tctgctgtaa gctcggcagt
    29221 agaatggatt cagaatgcat ggaaatctac aggagaatgg tttaacaatt tatggaagtc
    29281 cattaaagaa ggcgcagaca atgtttggac tacagttcaa gaagcccctg ggaaagcggc
    29341 agattggatt aaaaacaaat ggactggaac aaaagagttc ttttcaaatt tatggtcaag
    29401 tattgcaaac tctgcttcag agatttggaa tagtttaaaa gaaggtgtca tatcagttat
    29461 tgatgattta gtttcaagtg ctggtgaaaa atgggaaggg tttaaaaata ctatatctac
    29521 tgcatggaaa acaattacaa gtaaaatcaa atctggtttt gattttatac taaaatatat
    29581 tggtccattt gtaagtagct tttcagatgt gttctctaat atagtgaaag caataacaag
    29641 tatatttgct gaggttaaaa acataatagt aaatgcttgg gaaatcatta agtctttaat
    29701 agctgcgcca ctactgttta ttatagattt aattactggt gacttcgaac aaatgaaaga
    29761 ggatttagat ctaatctgga acacacttgt ccaatcagtg gtaaatattt ggacatctgt
    29821 aaaaaatata tttacggaat atatcggtgc aatagtaaat agtgccgtta gtttatggac
    29881 tggattcata caaagtattt ctaatatttg gaatgaagta gtttatcaag cgactatgat
    29941 ttggattgat ttgaaactat tttttactaa tttatggatt gatattaaat acagtgcaat
    30001 tcaaatgtgg ataaatctaa aattctccat aattcaaact tggattgata caaaatatgg
    30061 tgcaattgaa ctttggaata atctaaaaca atggtttttc caaacggtta ataatatcgt
    30121 gcaaactctt ataaaaagtt ggaacagctt aaagcaagga acgatagatt tattcaacaa
    30181 tacagttcaa ggtgctaaag acatttggac ttcattcaaa tcttggattg gtgatttaat
    30241 tactggaacc aaagataaca tcattcaggg atgggaaaac ctaaaacaag gtactataga
    30301 tactttcaac aatttagtaa atggtgctca agaggcatgg gataatttag taaatgctgt
    30361 tagtgacacg gttgatagag taactggctg gtttgataac ttgaaaaata tcgatttact
    30421 agcagccgga aaagctatca tggatagttt tctagaaggg ttacaaaatg catggaaatc
    30481 tgtgcaagat tttgttggag gtattggtga ttggattcgt gaacacaaag gacctatcca
    30541 atacgataga aagctattga ttccagctgg tcaggctatt atgaacggtc tgaataaagg
    30601 tctgacagga ggattcaatg acgtacagaa tactgttgga agtatggcag actttatcgc
    30661 ggaacttttc aatgcaaatt ctgatgtaga tatagctgca aatttgaaaa atgcaaataa
    30721 aaacattggt gcacaagttg aacataaaat aaatatgggt ggctctacta aaccagctgt
    30781 atttaaaatc aatcttggaa gacaatcgtt tagattgttt atggacgata tttcacaagc
    30841 tatgggcgaa ggtgcagata ttaatctgga attttaggag ggaatatttt ggatcaacga
    30901 gaaaataaaa tgtactcatt caaagataca accattaatc tcactagttc taaacgattc
    30961 cttccgacgt ctgccatgat gtacgatgga atgtatttag aagatttgat tgatggttat
    31021 caaacactta cggtggaagg tagagaaatg ctttctgtag aagttgaaca gcaagagata
    31081 caaattggtt caatcattac aaatcagaaa ataccttcaa gaacactaaa aataacatat
    31141 aagctggaag atagagatcc agaaaaacta cagtttaaat tcaaagaact gttgaattat
    31201 ttataccgga atgaagacgt ggaaattagg tttcatgatg aattagatta ttattactac
    31261 ggtcgctata catcaactga tactgttcca ggagactcca actcgattat ttcgagtttt
    31321 aatgtattct gtgcggatcc actaaagtat acgaaagagt gtgttagtga tggctatatt
    31381 ggaaatccga tacagtttcc tataacacca agaaaaattg aagttacttt atccatgaat
    31441 aattcaatca aaattacaaa cggagaacaa aatatcacga taactgacgc ggcaataaaa
    31501 acaggagacg tgttggtttt tgatttttcc gatgagcagg taactgtaaa cggagaagat
    31561 tgtacttcta tgattgattt agaaagtgat tttgagaact tttatcttaa gcaaggtcag
    31621 aagataacta gcaataatgg gaagcttaaa atattctata ggggggcgac aatttgagtg
    31681 agacagttta tttctttgat cacttgcaaa aacttattaa aagaaaaaat acaagaagtt
    31741 tgattgaagt ctcccaagaa aaagaaatta gttctgataa gagtgatcta atgaaagata
    31801 ctctttacgt tacgacaaaa tatgataaag aaatagagga tgcaagatat atggcgattc
    31861 gtgaaaacga gtcgtctttt tcgttgtatc gaattactaa agttagcgac ccatttgaaa
    31921 cattagagtt tacagggtta ggatttgcga caaatgaatt agatgcttac atcatcaaag
    31981 atattaggcc gagtgggcag cccttaaaaa atgttcttga tcgattgatt gaatttactg
    32041 aaggaaattg gcgcgttggt cacgtagaag caatgttacc aacagtaact gcaacttttt
    32101 actatgtctc tgtaaaagaa gcgttgaaag aattgcaaac cttaggtatg gaatttgtct
    32161 ttaggtgttc tttgaattct gatggaataa aggataaatg gatcgaagta tatgaacaaa
    32221 ttggcgaaga atcgaataca cgtttcgtat atggtagtaa agcattaaca gttgtaagag
    32281 agatagatag aagctcaatc tcaacttcaa tgataggtcg tgggcgaggc gaagaggttg
    32341 gtgacggtta cggtagaaga attgaattca ctgatgttga atggaaaaag tcgaatggtg
    32401 atcctttaga taagcctaaa ggccaaaatt ggcttgaaga tccggaatca actcaaaagt
    32461 atgggatacc acaaaaagat ggatcaatga gaaaacgaga aaccgtagta gtgtttgatg
    32521 atatagatga tccaacagat ttacttaaaa atacttattc aaccttaatc gattctgcta
    32581 gaccgttagt acaattcaaa gctgaagtca ctggaggaga tgtgatagga aatacagtga
    32641 ctattcacag atacgataaa ggttatcact ataaaactcg tatttataaa actacattca
    32701 atcggcttac cggtcaaacg aatatcgaac taggggataa tttaacacaa gatgttagaa
    32761 aacaaacggc ttctattgtc aataatatta atagtttaga atctagcaaa atgacatttt
    32821 acgaatcgac agagattgga aaatatcaag atgacattat gcgaggtgca ggagataatg
    32881 gcggttctat ttattgggta aatggaattg aagctggtgt tagtgatagt agagaaatct
    32941 atgaaactgt ttatatggat ggacctaaca ttcctagatc acgctttttt atggtccaaa
    33001 ataactcagg gatatctttc aaacaatgta aaaaaggtga gtggcaaaca attcaagatg
    33061 tacacaatgg tgatagcacg accgcttgga cgttggatgg aactttcaat gctaatttta
    33121 ttcgcgcagg cattctgtct ggtatcctcg tgcaaggggt agctttaaaa acatttgacg
    33181 ataaagattt ccaattagtg gcagaggggg gagaactttc ttttgaaaaa caagtcaagt
    33241 ctactggact agatgatgta catggagaac gcttgggctc aattgtatct acttatggtt
    33301 ctaaagggat taacggcttt gctgtctgga aagagccaaa ctatattttt tccattaatg
    33361 ctggggacgg tggcgatcga gggaatccta tttttcaaat tccagcagat gttactgctg
    33421 ataagcgcaa atataatctt tatggtgacg gcaatttttc agaaggaaat ataaccatag
    33481 atggacggct agatgtaaaa gaactctatg ttaacggtac aaaaattgac actaatggag
    33541 gaggcaattc cggagggaac gataacggtt ggaacggaca atacccacca gaagtaacta
    33601 ctgatcggga taaacgatat tggcaaattt gggcaacggc aataggtgcc ggttttacac
    33661 aacaagctgc tgcagcctta cttggaaatg cacaaggaga atcagatgct aatccaaccg
    33721 ctgatgaggg caatggcgca ccagggttcg gttatggtgt atggcaatgg accgattctt
    33781 ctggcgcaac tagcggacgt gtctacatga tcaatttaat gacaaaggct ggcatcagtg
    33841 atgatccaga cacaatcacg gcacagttta aattgttgat gtggcatgca ccaaatggtc
    33901 aatggatcgc aactagcgct tatccttaca catggacaca attcatgaat ctgaccgata
    33961 tcaacacagc agcacaagca ttcgtggcta actttgaacg tccacgtgat ccacatccag
    34021 aacggacggc atggtcacaa gaatggtatg acaagttcaa agatttggaa attcctgtat
    34081 caaaaggata tatgaagccg attgcggatc caatcacagt gacgagcgaa tttggctggc
    34141 gcacttctcc aatcacagga gcacaagaat ttcataacgg tattgacctt gtaaatggaa
    34201 atcctaatac acctattttt gcttcagcgg atggcgaagt gattgttgca ggtgatgcaa
    34261 attactttga ctggtatgga aattggacag tgattaaaca cgctgatgga atgtatacag
    34321 gatacgcgca tcaaagccga gtagacgtct caaaaggtca gaaggtaact gctggtcagc
    34381 aaattggact gatggggaca acaggaccat ccactggaga acatcttcat tttcaattta
    34441 tggatgagtt ttatccatct tcttcaggtc atttccacaa tgcaagagac tacatcgatt
    34501 tctaaaggag ggatagtcat ggcagaaacg cagcataaaa tggtcctatc caccaccgaa
    34561 ccaaacaacg gaataaattt ggttcgaatt cggcaagggg atgttttaac gcaaaagttc
    34621 gttgttgaag tggtggaaca tggcaaacta aaaacattcg agggcctagt gccgtttttt
    34681 attaatacaa caaaatttgg cgaaaaccaa cctgttgaac aaaaagtaca agaatacagt
    34741 ccagcgcaag caaggcttgt ttacacctta agtgagcctg actggcaatg gggtggtgaa
    34801 aacaccgcac atttcagttt ccgatcactt aatggtgatg gaacttggag tgaacaattt
    34861 agcacacagg attttaccta tcgagtcatt tctggaatat ctagaagcca gttacgtgac
    34921 tctggctatg tgtggacatt tgaggatttg ctaagaaaat tcaaagatta catggatcag
    34981 ggcaaaaatg actgggagca gtggttagaa gataatcgtg aaatactgga aaatatcgat
    35041 ccaggtggta tgatcattaa cattctgaat gaagctaaag gcgactacga atcattagct
    35101 gatcgtttaa accaaaaata ccaagtgcca gtcggcagct cacaaattag agaaacaaca
    35161 cgcttttttg attacgacac gatgaaatac gttgacctag tgccgcgcaa tttgaatacg
    35221 gttgtcaaca gtgttaataa cagcaaattt aacttttctt tcattacaga cattcacgca
    35281 gataatcaca acttgcgtat agatggcgtc ggttacaaag atgcttctta tttaagacat
    35341 tggcgcgcaa tccctcaatt tcaaaaatta gggaacaaaa cagatgtgat gatttacggc
    35401 ggagacaata tcgacggcgg acttggttca ctcggcagcg atataggcat tattgatgaa
    35461 tggagcgcgc gacattccat gttaggcacg ctcaaacgct tcactaacgc agcggtagca
    35521 ggacaagaaa aaccggttat tatctgcaaa gggaatcacg acgcttgttt cgaccccgcg
    35581 tggcgcaagc gaaagggaat gttatgcaac gctgacttcg aagagtattg gaacggtttg
    35641 tacggtggcg tgttgttccc agataaaaac gcagcaattt accgtttcga tacttgtgat
    35701 ttttatgaag gcggcacagg cgacaagtac gtggacggtt acagcgatac agcgccggga
    35761 gctttcagtg ccaaacaaat taacgctttc ggagaatggt tagtgaacgt tccgagaaac
    35821 tatcatgtgg cgttagtagg acatacgcct ttaggtctca gcaagtttcc cgttcgcaat
    35881 gaaaacatga ttagcacgtt gatagaaggg tttaaatctg gtagtccggt aactatcgat
    35941 tggtctaaat taggacaacc gaatgacggt tcgttcggcg gattaaagac cttcgcaatg
    36001 aatacaaaag gcgccggcgt tgtagtaggt tatttctgcg ggcattggca cgaacaagtc
    36061 gaaggggcgt ttggaacagt aaaaatgatt ctttgcgacg tcggcttctc tcatacagct
    36121 agccaagttg atacaccgga tgaattagcg ttttataaaa tagaagttga cacagcaaca
    36181 agaaaagtga caagcaaagg cgtagggcgc gcgagagact tcacttataa ctattaaggc
    36241 ggtgaacaat taaatgttag attttcaaag caaaccaaat atttttgaag aaatgagtta
    36301 tgaagaggct gtgaaatggt tattgcgtca agcggctatc cattacgacg gctcggatca
    36361 cgacgcgcac gtcctagcta ctgaaagcaa cgcgggcttt gctacaccgg aaacagttat
    36421 gcaagcgcgt gggcgttggt tacgcgatta taagctacca caaaaatatc cgaacatttt
    36481 agacattccg cccggcaaat acgcaaccaa agccggatgg ggcgcagaca accctgacgg
    36541 gattgaagat gacagttttg ttgaaatgat ggtattcgcg gatcacgatt cgagaaaatt
    36601 aatcgtcgct tttgctcgtt atagcggcga aatttacatc aaaatgacac ataacagcga
    36661 accggtagag ggttataact cgttaggctg gcggcgcgtt tacactactt ctgttctttt
    36721 tgaaggcgaa ttaagaaaag gacaatcagt caatctgcca gatgatactt tccgttacca
    36781 aacgcttcgt atccactaca cagacggtga cggagacttt gtagaagaag tgaaacgtca
    36841 aagatacgcg cgaattacaa aagcgaattt atggaatgga gacgcgggag tgacgttcat
    36901 cgaatttgag ctgacaatcg aagcgcgaaa gataacgatg tcaaacggca gagctttaga
    36961 tatttcatcc ggcaatgttt ccaatcccgc aatgagcaac aacgtgaaaa taactaagat
    37021 tgaaggtgtg aaataatggc gcatgtcatc aaaaaaggct ctatcaaagt acctacacag
    37081 ccgaaagact acgatttgca agcaacgggg cttgtattta aatcatacga taatcaaata
    37141 gcgttagagt tcaacgtcga acaacagaac ggcacaccgg cggacttgct aggagctaac
    37201 ttgcgcttgt tgatgtttat ctatgatgaa gtagatggaa tgatcacgaa agagccaatc
    37261 ccttttatca cgaaaaacct catcactgaa agcttcttga atggacaggt cgtatatatc
    37321 ttgccagaag cgatgaaagc ttataacggt atggtggaag cttatgttta catcgagtat
    37381 ccagacggat caacaagtga taacttaggc ttcaccttcc gtatgaagcg ttcagcaatc
    37441 gacggactag cgcaagataa agcagactac tttattgcag actttcaaca attacttgat
    37501 ggagtcaaac aagaagcaac agatgctgtt aacgcagcat taacaaatgt ggattctacg
    37561 attgaaaagg caaaccaaca aataaatgaa tttgtagagg gagccacaca agcaattgat
    37621 caaactgttg acgaggtaac agagcaacta caagctactc aaactaagat tgataccgtt
    37681 tctcaaaacg ttacatcggc acaaaacaat cttaaagcag ttgaagacaa gatgaatcaa
    37741 accaatcagc aaatcggcga cctcggcaag ctgaaaa
//
LOCUS       DASHXG010000025        36406 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.025, whole genome shotgun sequence.
ACCESSION   DASHXG010000025 DASHXG010000000
VERSION     DASHXG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.025"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            136..309
                     /locus_tag="U2R59_001434"
     CDS             136..309
                     /locus_tag="U2R59_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965832.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="U2R59_001435"
     CDS             949..1422
                     /locus_tag="U2R59_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HEM8965833.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="U2R59_001436"
     CDS             1431..1658
                     /locus_tag="U2R59_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965834.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="U2R59_001437"
     CDS             2294..2665
                     /locus_tag="U2R59_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965835.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="U2R59_001438"
     CDS             complement(2921..3163)
                     /locus_tag="U2R59_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8965836.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="U2R59_001439"
     CDS             complement(3195..4097)
                     /locus_tag="U2R59_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8965837.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="U2R59_001440"
     CDS             complement(4110..4298)
                     /locus_tag="U2R59_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEM8965838.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="U2R59_001441"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="U2R59_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEM8965839.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="U2R59_001442"
     CDS             complement(4913..5806)
                     /locus_tag="U2R59_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8965840.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6806)
                     /locus_tag="U2R59_001443"
                     /pseudo
     CDS             complement(5884..6806)
                     /locus_tag="U2R59_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            complement(6855..7205)
                     /locus_tag="U2R59_001444"
     CDS             complement(6855..7205)
                     /locus_tag="U2R59_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8965841.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7238..8140)
                     /locus_tag="U2R59_001445"
     CDS             complement(7238..8140)
                     /locus_tag="U2R59_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEM8965842.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8133..8990)
                     /locus_tag="U2R59_001446"
     CDS             complement(8133..8990)
                     /locus_tag="U2R59_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEM8965843.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9324..10133
                     /locus_tag="U2R59_001447"
     CDS             9324..10133
                     /locus_tag="U2R59_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8965844.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10173..10670
                     /locus_tag="U2R59_001448"
     CDS             10173..10670
                     /locus_tag="U2R59_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8965845.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11055..11128)
                     /locus_tag="U2R59_001449"
     tRNA            complement(11055..11128)
                     /locus_tag="U2R59_001449"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11092..11094),aa:Ile,seq:cat)
     gene            11315..11638
                     /locus_tag="U2R59_001450"
     CDS             11315..11638
                     /locus_tag="U2R59_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965846.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11802..12056
                     /locus_tag="U2R59_001451"
     CDS             11802..12056
                     /locus_tag="U2R59_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965847.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12126..12371
                     /locus_tag="U2R59_001452"
     CDS             12126..12371
                     /locus_tag="U2R59_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8965848.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12447..12812
                     /locus_tag="U2R59_001453"
     CDS             12447..12812
                     /locus_tag="U2R59_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965849.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12873..13436)
                     /locus_tag="U2R59_001454"
     CDS             complement(12873..13436)
                     /locus_tag="U2R59_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965850.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(14004..14204)
                     /locus_tag="U2R59_001455"
     CDS             complement(14004..14204)
                     /locus_tag="U2R59_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8965851.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            14600..14749
                     /locus_tag="U2R59_001456"
     CDS             14600..14749
                     /locus_tag="U2R59_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965852.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            complement(14956..15669)
                     /locus_tag="U2R59_001457"
     CDS             complement(14956..15669)
                     /locus_tag="U2R59_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8965853.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(15662..16747)
                     /gene="uxuA"
                     /locus_tag="U2R59_001458"
     CDS             complement(15662..16747)
                     /gene="uxuA"
                     /locus_tag="U2R59_001458"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEM8965854.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            complement(16764..17207)
                     /locus_tag="U2R59_001459"
     CDS             complement(16764..17207)
                     /locus_tag="U2R59_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8965855.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            complement(17241..17594)
                     /locus_tag="U2R59_001460"
     CDS             complement(17241..17594)
                     /locus_tag="U2R59_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965856.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            complement(17706..18107)
                     /locus_tag="U2R59_001461"
     CDS             complement(17706..18107)
                     /locus_tag="U2R59_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965857.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            complement(18144..18653)
                     /locus_tag="U2R59_001462"
     CDS             complement(18144..18653)
                     /locus_tag="U2R59_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8965858.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            complement(18675..19532)
                     /locus_tag="U2R59_001463"
     CDS             complement(18675..19532)
                     /locus_tag="U2R59_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8965859.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            complement(19550..20383)
                     /locus_tag="U2R59_001464"
     CDS             complement(19550..20383)
                     /locus_tag="U2R59_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8965860.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIVGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(20397..21194)
                     /locus_tag="U2R59_001465"
     CDS             complement(20397..21194)
                     /locus_tag="U2R59_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8965861.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(21227..21511)
                     /locus_tag="U2R59_001466"
     CDS             complement(21227..21511)
                     /locus_tag="U2R59_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HEM8965862.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(21508..22509)
                     /locus_tag="U2R59_001467"
     CDS             complement(21508..22509)
                     /locus_tag="U2R59_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HEM8965863.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(22511..23578)
                     /gene="gnd"
                     /locus_tag="U2R59_001468"
     CDS             complement(22511..23578)
                     /gene="gnd"
                     /locus_tag="U2R59_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HEM8965864.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            23577..24425
                     /locus_tag="U2R59_001469"
     CDS             23577..24425
                     /locus_tag="U2R59_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8965865.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            25071..25277
                     /locus_tag="U2R59_001470"
     CDS             25071..25277
                     /locus_tag="U2R59_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HEM8965866.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(25479..26480)
                     /locus_tag="U2R59_001471"
     CDS             complement(25479..26480)
                     /locus_tag="U2R59_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8965867.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(26485..28398)
                     /locus_tag="U2R59_001472"
     CDS             complement(26485..28398)
                     /locus_tag="U2R59_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEM8965868.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLVTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(28566..29072)
                     /locus_tag="U2R59_001473"
     CDS             complement(28566..29072)
                     /locus_tag="U2R59_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEM8965869.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            29232..29672
                     /locus_tag="U2R59_001474"
     CDS             29232..29672
                     /locus_tag="U2R59_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEM8965870.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(29698..30855)
                     /locus_tag="U2R59_001475"
     CDS             complement(29698..30855)
                     /locus_tag="U2R59_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965871.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(30858..31214)
                     /locus_tag="U2R59_001476"
     CDS             complement(30858..31214)
                     /locus_tag="U2R59_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965872.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(31512..32486)
                     /gene="sgrA"
                     /locus_tag="U2R59_001477"
     CDS             complement(31512..32486)
                     /gene="sgrA"
                     /locus_tag="U2R59_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HEM8965873.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(32682..33521)
                     /locus_tag="U2R59_001478"
     CDS             complement(32682..33521)
                     /locus_tag="U2R59_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8965874.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            33706..34593
                     /locus_tag="U2R59_001479"
     CDS             33706..34593
                     /locus_tag="U2R59_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEM8965875.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(35187..35881)
                     /locus_tag="U2R59_001480"
                     /pseudo
     CDS             complement(35187..35881)
                     /locus_tag="U2R59_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(35865..36263)
                     /locus_tag="U2R59_001481"
     CDS             complement(35865..36263)
                     /locus_tag="U2R59_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEM8965876.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT        10714 a         7219 c         5756 g        12717 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt ttcatctgtt
     6781 tctattacat tcttttcttc atccacaaag tagtatctca atgtatacct cctttttgga
     6841 ctttctcgaa actattagct gaagaagcag ttctttaatt tgatattata atcgagtact
     6901 gcgatttcat tttctaatga aaagctgtca agctgtttgt tgaagtccat gttcaatcgt
     6961 ttaccgaaat aattttgctc taatttagat gtatagatgt ccaataatgg atgctcgatt
     7021 ttagtcgcat attctccaaa ttccgaaaca aaaggaatga tttgaaaaaa gctgcctttt
     7081 gcaaaagcac ctttgtccct tagaaatgga tcggaatcat tgataagcgc gagtgcgatt
     7141 tttgtatttt ccccaacctt ttcaattaac gtctctactg catttttaga cattgtaatt
     7201 tccattccta ctccccctct tcagttgtgg tcttctatta tttaacaact acatctgttt
     7261 ttggttgaac ttttgcatat tttggatatt tagggaattt agctacacaa cggaaagccg
     7321 tcatccctgc atatttttcg taatatttct tcgttggccc ttcaaaatcc ttgctccacg
     7381 gtttcacatg tcctgaaaaa tggataatgt aaggattgtt gcgagtttct tcgtattcac
     7441 gttcacctgc tgctgttgga tgtttttttg cttttgccat gatatagcct tgtgcattcc
     7501 aacgcggatg aagtggtaac caacggtcat gtaagatagc atttaatgca tcttggtcat
     7561 ggaatcgtaa tttttctgga ttatgttcga tgaaatctaa tactttttgc gtaatatttt
     7621 catctaacca ttttttcaca ttgatcagca tcaaacctga gttgaaataa cgcattgatt
     7681 tagctgaaat tttcattttt tccagtcgtt gatggaaccc agcgtcttca acagctgcta
     7741 cgattgaatc accgaagtca agacgccata atttagagat atcttgtaaa gcgatcatgt
     7801 cgcaatccat atataagata cgttcaactt ctgtgccgcg gaacaattcc ggaatcgcaa
     7861 tacgataata agctgtttct ggaatacgat cgctgattac cacatttgta aagaattctt
     7921 tattgatttt caagaattcc acatctgagt tcattcgtgc gtttttcact gagaagcgta
     7981 aaagctgttt actttcaaaa tcgatatcat cgtcaatcac atagaaccga acaaatttag
     8041 acgggttgca attatctaat actgagacaa ataatgcagc taaatgtggt acgaattttg
     8101 tgttacaact tgcgactact gctatttctt ttttattcat tgatctcgcc tactttcgtt
     8161 agagtactgt gtgctaattt ttttaagtat aaattggtat acggatgatc tttcaacgta
     8221 ttccaaggtt tatcatgtcc tgtaaagtga acgatcgaag gtttttcatt tccttcttta
     8281 tactgacgtt catatttttc atttggtgct ggatgacgtt caaaaatcag cgaagtctgc
     8341 atgttccatt ttggatgaag ttgttcccaa tcttcataaa gtacagcatt caaagcatct
     8401 tggtcgtgat agatgattcg atcgccattt tcactgaggt aatggatagt tttttctgta
     8461 atttcttttt tattccattg atcaatgtca atcaccatca ctcctgaatt gaagtacaag
     8521 tcatcggaat cgattcctaa tctttccaaa gctttcactt ggcctggatc gataatagcg
     8581 ccgattgttt ttccatttaa cggctcatca tatagtttta cgatatcgtc tagtactaac
     8641 acatctgaat ctaagtaaag gactttctta taatcctctt tagctaataa gtttggtaaa
     8701 gaaattctta agtaagcggt agttgtgata tggtcactga ctaggaagtc ttcgtagata
     8761 tctttttcca ctgtcaggaa ttggatactt gcattacttg aatatttatt taccgtttct
     8821 tccaatcctt ctttactata ttctgataga ccatcgtcaa tcacataaaa ttttatgcgt
     8881 cttgttttat tgcaattttc taatgcagtt gcgatcatca cgctcaagta aggagcataa
     8941 ttttcgtctg aagcagttac cacaggaact acgccgtatc tcttctccat caaaatcact
     9001 cctttttcta atctttttct aacctgttct acatctagaa tattcctcat ttggttttaa
     9061 agcaaaatat atgctttgtt ttcattgaat attttaaaat ttttttatca caaaacgcat
     9121 cggtaagcgc taactattcg tttttcatgg ctttttattc aaaggtattg accaaaaact
     9181 actatatata gccacctttt tcttaagaat gttttttgaa aaaattcata atgacaaagc
     9241 aagttagttt cattttttta aattctcatt taatcttaag gtaacaggaa aatagatatg
     9301 taaaaagaaa gtaggaagat aaaatgaaac tagcagcgat tgatttagac ggtaccttgc
     9361 ttgatcgaaa tggaaagata ccagaagaaa atatccaagc acttcggaaa tttgatgaaa
     9421 atggcggaat cgtaaccgtc gctaccggaa ggaacagcat ttctgctaaa gatatttttt
     9481 ccgaattagg aatcggtggc tatttgattt cttccaatgg ttcactgatt gctgaaatga
     9541 aggatggaaa aatggcgaaa gttctcagac gttcaaaaat agatagcgat acactgagaa
     9601 aagccttctt ctatgctcaa gaagcgaaaa tatccatcat tgctagccga gaaacccaag
     9661 atgatcagct gacattcgat gaatcaaatc tagtcaaaga tgacccttat tatgaacatt
     9721 tcaatttaca gaaccattct tttgatcaaa ttttaaatat gttggaagat ccttctctta
     9781 gctatcttaa attagcatta acagataaga gtgaagaaaa actacagaag ctacaaagag
     9841 atctgcaagc agatggtatc caatcagtat tctctgatcc gcatttctta gaaatcacgc
     9901 ctacaggtat cactaaagct cattcacttg tttttctggc ggattacctt ggaatcgaat
     9961 cgagtgacat catggctttt ggcgatcaag aaaacgacat tgctatgttg aattacagcg
    10021 ggttgagtat tgcgatgggg aatgcacagc gacaagtaaa agaaattgca aaccaagtaa
    10081 cactgacgaa tgaagaagct ggtgttgctt atattttaaa aaacttctat taaaaagaat
    10141 aaaatgacga tatgaatgta ggaggaaaga aaatgttagt tattattgat atgcaaaatc
    10201 atattcttga tccaaacagc gaattttata ttccagagtc agatcaattg gcagaacgta
    10261 ttgctcaaag attagctaaa gcacgccaaa ataatgaata tattctcttc acacgggata
    10321 taccagttga actgaaggac aaagaagaag aacgagaaga tttgcaattg atccctcttc
    10381 tttctccaca agaaaatgaa cgagtgatta aaaagtatta ctttacgatt ccacctgaaa
    10441 ctttagctga aatccaggaa actttatttg aaagcaaaga agaacaaaaa gagatcgaag
    10501 tagtcgggat tgaaacaaac ttgtgtgtac tctctaatct gataggcctg cagagtgctt
    10561 ttcctgaagc agactttttt gttgatccaa tgttagtctc cagtagaaaa cacggagaat
    10621 ccgctttaga gctgttgaaa gatttcaacg tctctatcgt cgaatcataa aaatatctat
    10681 cttcatttac gatatttaac acacaataaa aaaagcacgc agaactgttt tagtcctacg
    10741 tgctttttct atcaaagtag attggctttt ttatgacaca gagtgaaacg gcaggctcac
    10801 gacctctttc ttaaatggtg ttcaatcagc tgaccctcgg tattagctta acaaacggca
    10861 aaatatgagg aactattttt ccgtttgtta agctaatact caggtcaaaa cgctgatttc
    10921 acaacctctt ccttaaacgg tattcaaaag cttgcatctg cagtaataag aacagccaag
    10981 taaaaacata agaagctgtt tttacttggc tgttcttatt acttgatgca gggcagcttt
    11041 ttcacaacct cttatgtacc ttgtaggact cgaacctacg accggacggt tatgagccgt
    11101 ctgctctaac caactgagct aaaggtacat cataaataaa atttattttt gttacttttc
    11161 aactatagca cgaatgacaa actctcacaa gtttcaaaat ataagtaaaa taatattgtt
    11221 attcttattt cttttacttg tgtcataact attttgttac tttaattttt atttgcttat
    11281 tttagaaaaa atgttattct tttatttatt ctcaatgtta ggagtgatta ttttgccatt
    11341 tattgcgatt ttattcgatt tagttgcggc agcagcttat tttctccaat taaattatca
    11401 aacctcagga attctgttta ttggaatgat ttttcaaggt gtgattaccc ttttgcttct
    11461 tgtcatgatg ctcagctata aaggaaaaag atatgcccgt attcaaacaa aagtatttgt
    11521 taaatatgtt tccattcgct atgggatcat cattctttcc tttttagtga atgcgatcgt
    11581 cctcttttta tatgtattga attacttaga tatcaatcca ttgatttttt ctcgatagat
    11641 aagacacatt cagcggaaca gttcctgctt atcagcagaa aactgttctg ctttttcatt
    11701 tttcattgat ctattcttct tttattttcc tagcatttca tttgtgatgt atgcaataac
    11761 atgttatctt ttattatatg aatcgttgag gagtccgtta catgattacg ttggtgagag
    11821 ttttgttttg ggtgcctgcg gtcgcactgg tcgcaagtat tgtttatctt atgaattgga
    11881 acaaagaacg gttttattta gctattttga ctcttccggc tatctacttt atgtggaaag
    11941 tttttaatta caactacttt gaacccgata gtgtttttat agaagaatta tcaggactgg
    12001 ttttgtcttt attgatcgtc attctttatt tgatacgttt aaataaaaaa cattgagtac
    12061 tattgattgc atgtgtagct ttctatagtc attataacta ttctactata atgaaaggtg
    12121 attaaatgag tatcgaagaa gctattttac tggatacttt acgttgtcgt ctgaatttct
    12181 taagaactgg ccgatcttta tctcaagtag ctgtttctag cgcgttaagt attcctttat
    12241 tcaaatatcg taagtacgaa gaaggagaag aaattccaag catcattgaa ttaatctata
    12301 tcgctgactt ttacgatatt tccgttgatt acctaattgg tcgctcagaa acagcaagca
    12361 aactgaagtg attttttcca gccttggtgc tggttttttc atttaacgtc taaggttaac
    12421 aatctatata taaaggagac atttctatgc gattatggca tgaaaaattg atttcaaagc
    12481 ttcctcgtca acagctttta ggacaacatc gggaatgctg tgcattaaga ggaaatggct
    12541 ggggaaagaa acatgctact gtggattatg tttttcacta ttctccttat agattattcc
    12601 aatatcatca gcttgtcatg gatgaaatgg aaaaacgtgg ttacagccca gcaccagagt
    12661 ggaaaaatcc tatgtatcgt ggcaaatcat gcgaagcatt ttttgattta cctactgtag
    12721 agcgcaacgt gccgatttat ccggaacacg atgaagttta tctagcagaa tgtttagcaa
    12781 atttggagca aaaaggaatt tatcttacct aatataacta gaaaagcctt ctatctcctc
    12841 ttacttcatt aaaaagcttt aaccatctta gatcaagcta aaatgtcgta agttttaggg
    12901 ttatcttcat cctcacgtgc aaaactaaaa gcgtactcta gttttggttc atcgccaact
    12961 tccctagaca taaatgaaca tctcctgacg tggtttaaaa gtaccgcatc ttcgacgtct
    13021 gtatacgatg cacagcacag attgcttctt ttgatctttc ttttgatttt tctgttgctt
    13081 cttctacacc ttcttcgatt actacatcga tgcttacaat tgcttctgcc taatattccc
    13141 atgcatcgtc gatttaagcc tctgtagtca ctgtgatcgt ttccacattt taactcctct
    13201 gtcgtggctt cagttgattt tgtgatcagt tcagttgcta agccagagtc agaacaacct
    13261 gccattgcta gcgttaatat tgatagtaaa aatagttttt ttatcataag gttccccccc
    13321 tgaaaataga ctaaaataat aacgctttct ttttttgttt tcagacgaaa attaataatt
    13381 tctaaatatt ctttaaaaaa gcttataact attatgcctt ttttaatata taacacagtt
    13441 atttttaaaa ataagaatgc taaatcactc tacaataacg gcgaaagcac aaaaaataaa
    13501 aaaattatta cgttattaaa aaaacagatg aaagatcagg ttttattaga tctcattctt
    13561 tcatcacttg aagggattta atgaactact ttttcctctt tgtcgttttt atatattcgt
    13621 attccttcaa acagtaggat agcctctttc aatgcttgat atttgaactg tccgttactt
    13681 aaaaatttag atgtgccgcc ctcttcctag aacatattct tttttacttt ttcattaatt
    13741 gacagaccaa tcgaacgaaa ctgtaaattt cgataggata atgattggtc aaactcattc
    13801 attttcaaga catctcgatt catattcaag ataggaatct ttttatcaac atcactttat
    13861 tcgtattttc ctctaccata aaagcttcac gctccacaaa attgttttat acactactat
    13921 tcagcccatt caacgaccaa tgaatttttt cgtacaaaaa aaccgtcttt tctttcgaaa
    13981 agacggttaa aagtcaattt ttattaagct ttaacaatgt ttgttgcttg agggccacgt
    14041 tgaccatctt caacatcgta agacactgct tggccttctt ctaaagtttt gaagccgtca
    14101 ccttggatag ctgaaaaatg tgcaaataca tcatttccat cttcaccagt gataaagcca
    14161 aaacctttgt ctgcgttgaa ccattttact gtaccgttat tcataaataa attcctcctg
    14221 atacgtatca atgtacgttt tttcgttgca ataaatattt gataggcaaa aggagtttta
    14281 tctatgtaga tatatcgctc aaattacgtt tcaaaataga ttactcattt aatatatcat
    14341 gctttttcta ataacacaag gataatgcaa tgaaatataa aattcattgt cttctattgt
    14401 cttcgaatcg aagaaaaagt tgaataaccg cgattgattc actttttgtt ttcttgttta
    14461 tttgctttta tctgcaactt ttgactttaa aatttcttaa ctatgaaaac ctttcaattg
    14521 gtggtatact tataaatgga atttcgttat caacgcgttc gttgcctttc agcaagtatt
    14581 taaagaaagg agaatggcta tgacattcta taacaaagat atacaatatc gagtaacctt
    14641 ggatacagat ttgaatctat ttgtcgtttt tgacaaagaa aataccaatc atgtagcgac
    14701 aggtgttacg atcgaacaag cagtgcaaga attaaaaaaa tctgcataag gagtggaaac
    14761 cctcatatgg acgattctcg ttcttctctt taaacgcatc tactggtaga taacagtaga
    14821 tgcgttttgt gtttgttcta aattgttcac tacaaataag gtagatactt caaaataaaa
    14881 aattacttct ttttcatctg ttccctcagt cgtgcaggac aataaataaa gaggactaga
    14941 aaatagtcct ctttattaga gatacaaccc tttactttct aaaaatcgtt ttgcttgatg
    15001 caggtcataa aattcatagt ctgctttatt ggattcatat aaacttacat ctactttcaa
    15061 cttatgcttc ccattatgat cgggcaaccc tatcaaatga tctttgatga gaaaagacaa
    15121 aatgcccgct cgccttgctg cttcgatccc tgcaatcgag tcttcaaata caagtgcttc
    15181 acttggagga atattcattt ttgaacaagc tttcaaaaag atctctggtt ccggctttcc
    15241 tttttttaca tcatcccctg aaatgatttg atcaaacaag gcatatagat tttccatttt
    15301 taaatacatt tctactttta cccgtgtatt agacgaagcc acgattgtat ggattcctct
    15361 ttcttttgca aaagataaaa tttcttctgc tccttttttc gtatatactc tcttatcttc
    15421 tttcacgatt ttttctttat attgattgat tgcttctcgc catttgatat atggaacatc
    15481 ttctccgtac aaaatgccca tttgttctct tatcgccatt tctgtttggc cagttagtaa
    15541 ataatagact tccttacgca tttcataatc atacttttgt gctgatttta cataagcacg
    15601 ataagctaaa cgtccagttt ctaataaaag gccatccata tcaaagatga agagcttgat
    15661 tttattcata atgctctccc agtggttttt ccttacttat cgcctcatat agaccttgca
    15721 tgtaagtgag tcccattgca cgatcataca ggccatatcc aggcatagcc acttcacccc
    15781 acacggttct accatgatca gggcgtatag gaccgtcgaa cccttcttgc accaacgctt
    15841 tcataatatg atacatatca agggagcctt ctgtagaggg atgtgccgtt tctttgaact
    15901 ttctttctcc taaaaactcc acgtttctga agtggacaaa atggatgcgc gaacctacct
    15961 catggatgat ttcaactaaa tcgttttccg gatttgcccc taaagatcct gtgcacagcg
    16021 ttagtccatt atatggagaa tctactgcat ttagaatttt cttcaagtcg ccaagatttt
    16081 tcgtcactct aggaaaacca aaaagttccc atggcggatc atctggatgg atagccattt
    16141 ttacatctgc tttttcgcac actggaatca ctttttctaa aaaataagtc agattttcaa
    16201 ataattcttc ttcggtcatt ccttcataca gtttttccag ctgagcgaat tttttcaacc
    16261 gttcttcttc ccaacccggc aatttgaatc cctttgactg gctgtgtatc aattgataca
    16321 tttctcctgg ctccatctga tcgacgattt tctgatcgta taaaagagaa tagcttccat
    16381 cgttgttttc attaaacaaa tcagttttcg cccatccaaa aattggtttg aagctataac
    16441 aaatcaatcg aaccccacat cgagacaagt ttttgattgt tcgtatatag ttatcaatat
    16501 agtaatctcg ttcatctgtc cctgccttga ttgcatcgtg gatcgctaca ctttcaattc
    16561 caagcagttc cagtccttgg ctctcaacag atgctttcaa ctcctcaatt tctgaaatct
    16621 cccaaacatc tccaggcatt ttagtcagca aagttccaat tatcccattt attcccggta
    16681 tttggcgaac atattttaat gggatcgaat cccctttttc accataccat ctaaatcccc
    16741 acttcatctt ttcagccttc cttctaaaaa tcgtcctcat ctaatttttt ttcttccgct
    16801 gaagcatgcc aaacagttaa attatctttt ccttgtttga caatttgttc caccgcttct
    16861 tctatcggtg tgtgaagcat ctgatgattg attgcttcta acaacattgg cagattcacg
    16921 ccccctatga cataagtggc tgctttcttt tcttcagtca gttcattgac tgccaagagc
    16981 gcttgattgt acggacttgc gctaattaga tcaacaaata ctagcatggg ttctgctgtg
    17041 ttgatcatag ttaatttttc tttgaccttc tctccgaatg tttggatgtc ctccccagac
    17101 tctaagcaca ttgtttcaat atggctcgat gtcccgacaa ttacttccgc cgcatctttc
    17161 agtccttcgc tcaacttacc atgtgtaacg atcatgattt ccaacattag tcttctcact
    17221 ccttgttttg cactttttac ttatcgaaaa agagcaataa tctgattggc attttgccaa
    17281 ttaaatgttt tccctcgtaa atctgttttg gtcaaataga agaactgcgc ttgctttttt
    17341 cttgcactaa aaatataatt gacgtttttt tctttcaact tatcaacttg tttcagccac
    17401 tgttctttat ttgaaaaata atttcccgaa aactgtagcg gtgtatctgc cccaacagag
    17461 tctagataaa aaagaatagc ctcttttttc atacccgatc tcacgctgtc taagcccttt
    17521 tctccataac agccttcatc aacaaacgca tacgctacac tcggatcatc aatcgtacgg
    17581 atcatttcta gcatcgttaa tatggatgaa gtatttcgaa taaaagtttg tctgctaggc
    17641 catccgcgag ctgcttttcc caataagaaa aagtagctcc caaatgctag tacagtgata
    17701 cctgtttata cggatagcag atcgaatacg tgatgaggat ttttgttata tatcatcatt
    17761 ccccaccaac ctaaactgaa caacaaaatg aaggacaata atatagagta gattgttttt
    17821 ttcctttggt ctttccaatc aaacatgaaa taacttccta atgcatgaac gggtgtatcg
    17881 taataagtac agataacttt ctctgctttt tcgatatctc caacataaat attttttgat
    17941 cggtaggcta gcgtatcgta agcaatgact gtcacatctg ttctcatact gtaaatatct
    18001 gatactaatg ctgaaagaaa acgctgttta ctcttttttg tacggcgctt acggtaaata
    18061 tagcgataac gaaattccca atcacgaaac agctcgttct tcttcatttt ttcgccctct
    18121 ttatcttttt tctaagcatt tgtttatgac aaatcaaact tgttcaatac atcttttaat
    18181 cctgttttag gtgcagatgg agtggcttga aaataaatat tctttacgcc atattgttca
    18241 ttcatttctt tcaatttttc agcatctgat ttatttaaat aaacagattt cgtcactaaa
    18301 agatctgtat caggattttt ttgagcaatc cctccaatat tcaattcttc catggggatt
    18361 ccgtgtttta ctaagtcgta aatcgtttgg actgtttttg cgatcaaaat acaattgtat
    18421 tctttaaatt gatattcatc ccaatagaat ttagctttct ctggtgtaat gacaattgtt
    18481 ttttgtcctg tacggcttcc tgcatttttg taaagatctc tcataaattt atcttttgct
    18541 acaacttcgt ctacaacaaa aatggaattc actccacttt tttgagataa cgttaccatt
    18601 acttgcccat ggatcaaacg ctcatccaca cgcgctaaat tgactacacc catcttattc
    18661 acgttccctt ctttttataa aataccgatt cctgctagca caattaatat tccagtcagc
    18721 cataataatg cttgtgtgac tttcaatcct tttttcgtat agaacaagta cacacccatt
    18781 acgacagcta aaggtaatat ccctggcacg atttgatcaa gaatttcctg gataacaaac
    18841 tcacgtccgg atatcgcaaa tttcaatgaa gattctactt ttacatagtt tcccgcaagc
    18901 acccccatca taaacaaccc taaaactgat agcatttcaa tcgctgtctg aacaccagtg
    18961 ttttgcatta ggcctgtagc attacggccc atagtgaaag cttgtcttgc gaaaaatacc
    19021 cctagtaaaa cctgatacaa cccaaagcag ataaaaggaa aaagtgcgcc taaaggactt
    19081 ccctgttgtg cccaaggtac cgcgattgcg ataaaaatat attggacggt tcctgaatcg
    19141 attgcatctc cgattcctgc tagtgccccc atcaatcccg ctttcgtgtt atacatcaag
    19201 tcatcctgca tcaagatctc tttttcttca tactcttctt ctgctctttg ctgttccata
    19261 gaagacatta ggccagtaat cacaccgcca ccccagctta attgagtgtt gaagaacagt
    19321 aactgccgtt tatatgctgc ttttaaagag tcttcatctt tataaagttt tttcaagatt
    19381 ggcatcattc cgtatagtag tgatggcgcc aagtaacgtt caaaagagtg aggaatttcg
    19441 tttgcaaaat gccatctcag ataggctttt gttacatctt ttttcgtgat ttcttcagga
    19501 gcacctgttt gattatccat tatttcagcc atttcccatt cctcctaaat taaaatccgt
    19561 catcatagtc atcttcgtca tcaaaagatg ctgaattgtt attgcttgtg gcaggctgta
    19621 cttgtttccc tttttgcgac tggacaaaga tcaaagcgat aataatccca aaaatggcat
    19681 aagtaaccat cgtaatatct aaagatttca aaacaacact cataaaataa gcaaggaaga
    19741 aaaagaccag ataatctttt cgaccgataa cgtatacagt tgtcgcgata ccgattgccg
    19801 ctaaccctcc acctactact tcaagaatgt ggataacgac tgttccctct aaagctttga
    19861 ttacatcagc gatcaatggc gcccctaaat ataaagcaat gaaaacaagc ggaacgaata
    19921 ataaaaatga ggcaaccgtt ggataaagaa taattgatcg ggccatagct tttgtattca
    19981 aatcttctac agctttgtct gtatatttac ctaaaaaagt attgatgaaa aaacgaaact
    20041 gatacaagta acttccgagc aatccgactg gcaccgcaac ggcaatcgct gcttctggcg
    20101 acagatcccc taataatgcg actggtactg cgatagctgc tgcaatagat ggttcagctg
    20161 gcattgatcc tcctggagaa aaaaccccca tataaatcat ttgcaaagcg gctgtaacaa
    20221 tcatcgcttg tgcaacttcc cccacgatca acccgacgac taatccagtc atcaaaggag
    20281 aaaaacgtaa ggtcaacgtg gctcctccac ctaaccagcg ggacataacc gcggctaccc
    20341 ataaagcaat caacaaactt tgtactacac ttaatgtttc catgtgtcct cctccttcag
    20401 atctttctga tataaccttc cagttccatc attgactgta tcagtgattt ctgtgttacc
    20461 tctataggaa tcaaatgcac tttctctttc gaatcaataa attcagccat tttatctatt
    20521 atctgtttat ctttcggaaa taatcccatt tgttctagag aaaccggcag ttctaattcc
    20581 cgatacaaag gatataactc gtctattttt tcccagcgac cttctagtgc cagttgatag
    20641 aaaatcccat acgctacttt ttctccatgt agaaaacgat ggctttccgg aatatattta
    20701 ctgatagcgt catgcatagc atgtgctgcc gcatttcttg cgtatttatc tcctaatcct
    20761 ccaactaaac cagcaacagc aaagataatc tctgaaagct gtttgaactc cgatgtcagt
    20821 tttctttgtg ccatatcttg gattgcttta gcagaatgat tcaaaatctc ttctttgcag
    20881 atcttcgcag tatcttgtgc tagcttcaaa aatgattcat cttgcaaaaa atcttgttct
    20941 aagatgagct cagattcata ccattttgct agtgtatctg ctaacccggc aatgaaatat
    21001 ggaacagggg aatcaatcac taattgggga tctgttataa aaaaagcagc ttgtctgtaa
    21061 aagtgttctg ttttcccttc tgcttgtcca ttctccttat acatgacagc aagaggtgtc
    21121 catggagcac aattactagc taaagtaggg atgactccga aatcgattct tgcaagattg
    21181 gcactataac ccactagatc ggtcagtttt cctccgccaa cgccaactac gaaatcgatt
    21241 tcattttttt gatgattgta gctattcgtc tggcttcagc ataactacat tctccagaat
    21301 aacgatgata aaaaaattga atcgtttcgt cattcaaaaa tactaattta ggtagcgcct
    21361 tttcccatga taccgttccg tgggtgacca gtactctttt cgcgccgtat gatttcaaga
    21421 gatcagaaac ttttgaaata ccaccttctt catataaata aaattgaggg cctgttttca
    21481 cttttaaacc gttcaccatt ttcttcatca tccttttata tagttgctct ttgtctggac
    21541 agaacgttca ggaagaaggt gctgactgat ctgttcgaca tctctgacac atttttcacc
    21601 cattgcttct aaacattccc ttgtgtaggc cgatatatgt ggcgtaatca ctacttgttc
    21661 aaacgctaaa tacggatgat cttgacgtcc cggttcttct tctaaaacat ctgtggcata
    21721 tcctgcgatc tttccgcttt tcagaccatt aatcatcgct tcttcatcaa ctagagcgcc
    21781 tcttgcacta ttagatagat aaacattttc tttcatctga tcgacttctt tatcagaaat
    21841 catgtgatag ttctcttctg tcaaattcgc acataaacaa atgatatctg attgttccag
    21901 taattcttga agttctactt tttttgcacc aaagctttcg atgtataaat ctgatttgta
    21961 aggatcataa gctagaacat cacagcgaaa accgttacgc aaaatttcga ttactccgct
    22021 tccggtattt cctgcaccaa tcacaccaac tgttttgtta aacagcgtcc taccgacgaa
    22081 ctccgcccga tcttcccatc gatcgtcctt gactcttgct tgtgcttgtg tcgtgcgtcg
    22141 aagcatggac aacaaattag ttatattatt ttctgctaca gcatttcgtt caattaaagc
    22201 aggtatgata gatacgattg tctggtgttc ttttgctgct tttaaatcaa tattgttgta
    22261 accaatacca tgtcgggaaa tcaatagcag ttcatctttg ttttcaaaaa aatctcgtcg
    22321 aaaaaatggc gtaacacttg caataatgat attgaatcct ttaagtaact ccgctagttc
    22381 ttttcctgga atctcttgat caacagtaaa gaaatgaacg tctccaactg actttaatct
    22441 ttccaagtgg tgtggaaaga ctcttccgaa actgctggaa ttaacgattg ctatatgata
    22501 atctggcatt ttactcaccc ttttcaacta tttcatgtcc gccaaaccca tttcttagtg
    22561 ctgaaactac ttttgctgaa aaactatctt cttcctgtga aagattcctc atgaacaaac
    22621 tagttgcaat tactggaact ggaacagcca tttctagcgc tgtttcaacc gtccattttg
    22681 cttcacctga tgcagaaacg attccccgat aattacttaa attgggatgt tcgtttaact
    22741 gatcttccat gatttccatc agccagccgc gaatcaccga accatgattc caaacacgtg
    22801 cgacttgttc caagtcaaaa gcatactcac ttttttgtac aagttggaat ccttcaccga
    22861 ttgcttgcat cattccatat tcgattccat tatggatcat tttcaagaag tgtccgcttc
    22921 cggatgcacc agcatacaga tatcctcttt caattgctac atctttgaat aattgttcca
    22981 cggatagaaa agtttcttta tctcctccaa tcattaagca ggcttgatgt cgtgctcctt
    23041 cgattcctcc agaagtccca caatccaagt aaccgatttc atttttctga aactcttctg
    23101 ctcgacggat tgaatcttta taataagagt ttccgccttc aataataatg tctcctggtc
    23161 cgagttttgg aaaaagtttt cttaacatgt tttcggttat ctctccagca ggaagcatta
    23221 accagatgat ttttttctgc tcaaaagtag ctagaaattc agagatctct tgataagcag
    23281 gaatgtcatt ttctcttgcc tgactaacag ctgtacttga aatgtcgagt ccttgtactt
    23341 tgtgatggtg ctcttttaag tttaaagcta aattcaatcc catttttccc aaaccaatta
    23401 caccaatttc catgatagcg cctccatttc ttataccctc attatacaaa aaaatttttt
    23461 tgtaaataga ttttacaaaa atattttttg tttgattttt tcctactctc cttgtatctt
    23521 taacattaat gagaacggaa aaaatgataa tcttattatg aaaatgagga attctcatga
    23581 gcgtctccat aagactacaa atcaaaacaa tgtacaacga cttcagccca aaagaacagg
    23641 ctatcgccga ttatatttta gaaaatccaa gcaaagtaag tcatagtcct attagcaatt
    23701 tagcaagtga actgggcatt gctgactcta ctttttttca atttacaaaa aaacttggtt
    23761 ataatggatt taaagatttt aaaatggcca tgttgatcca agaaaatgat ctatctgcta
    23821 tttctatcca cgaaaatatt cagaaaacag atactgagct cactatggcg caaaaggtgt
    23881 tcgagtctag tatttcaact ttaaatgaca caaaaaagtt gttacaacaa aaggatctaa
    23941 aaaaagcggc tactattatc aatgaatcta aacgtgtcta ttttttcggt gttggcggtt
    24001 cagagattgt agcaactgac gcttatcata aatttttgcg ttcccctatc gcaacttctc
    24061 acagcacgga ttaccatatt caattgatgg aagcttcttt attgacggaa aaagactgtg
    24121 ctgttttgat ttctcacaca gggcaatcaa aagaaacaat ccatattgct gaaaccgtaa
    24181 gaaaaactgg agcaaaaaca atcgttatta ctagccaagc taattcttcc cttgctaaac
    24241 ttggcgatgt cgtttttatt tctatttctg aagaaacaga attccgatct gaagctttag
    24301 cttcccgtat ttctcaacta agcattttgg actctctata tgtgattttg atgttttaca
    24361 acgaaaaaga atcacgtcgt tctatcgcta aagttcgaca tactatttct gaaatcaaag
    24421 aatagcacca taacagaaaa agcgaaaaat ccataaaaca aaaaaagcca ctaccaaata
    24481 tttggtagtg gcttttttgg ttctgcaagg gtggtacaga acatcaatag tcggtgggtt
    24541 agaacgtatg tcatcgcatc tttggagaag gttgtattgg tattattcga gttacttgtt
    24601 agatgcgata acaaagttag tatacagtag taaaaaattt atcttttctt ttttttatta
    24661 tttttgtttc ttattttcta aaaaattaaa aaaaattttg gtgaattaag tatttccttg
    24721 ataacactgg cttttggcct cattttaggt tatcatttgt aattttattt cacagttgat
    24781 atgattgtta tgtaaaataa aaaagtttag gatacatcga atttttgggg aaattctttt
    24841 gggggtatcc taaatctttt ctattatatt cccatatttt ctattattgg tctagacgta
    24901 tgatggtaaa ctttgtacct atctgattgc tgaatcatta attgcttatc attagccatc
    24961 tttgtttcaa gttcgctaga tgatcatttt attcacatcc taacaaactt gtcacattta
    25021 tagattctta atctatttat catacaatta taaaaaagga ggtgctgctt atgaaagcta
    25081 tccatatttc tttgcttttt ttcgctagtg cattgatttt atttgctatt catctttgtt
    25141 cccagcctta tatcaataac aacggaatat tagtggaacc agcattcttt tgcttaccac
    25201 tcggcttttt gtcccttctt gcctccgcag gcttcggatt tgttgctttt tttaaacgat
    25261 caaaacaaca aatctgactt ataaaattta cgtaaaagag atcgtgacaa taatcgtgtg
    25321 atattcccaa atttcgaata aaaggtgccc cttgccatct ctaactcctc agtcacaagt
    25381 tacaatattc ataaaccatg aaaagcttgt ttattgaaat tgctccttgt gacttggagc
    25441 taagtgacag attacaacct cttttgcatc ataagacttt actccttgaa aaacattact
    25501 aacttttgat atgtttcttg cgcttgttta ttgctgaaat caaactgata ttcatggttc
    25561 aaaacagcat ttttctccgc ataatctact tttgtgactt tcacccccgc tttctcaaat
    25621 acagaagtta cttcttccat ttgtttcgta aacgtatttg tatttccatc cgttaagaat
    25681 gtgttttgcg tccaacgatc cgcatgtctg accaaggcta aacttttgac cttctctgat
    25741 tgttcaaagt ccttattatc aaagtaagcc catccacatt tttcataaag aaagctagag
    25801 attttatcac ttacttgagt aagtgcagaa ggatccaaca gaccagacaa agaaataaac
    25861 ttcgtaatct gcttgttctc caaagtcgga tcaagatgat cagctttttt aatttcttca
    25921 ttttgaagtg ctaacaaata ttctccacta atttgtgcac ctgccgaatt tccaccaatc
    25981 gaaatattcg accaatctgc ttgatctttt atctcttttt tagctgcttg aatggcttcg
    26041 ttcaattgga taactggtgt aggatgtttt gcttccggtg atcgttcata atctatattt
    26101 acgatgattt gctgcgtgtc tgaacataga tattccaaat aatcacgaca atcattttta
    26161 tcccctccta catatgcgcc tccatgcatc cagaaaagaa tcggtaattt tttcttttcc
    26221 actttcggtg tgtagatatc catattatta tttttgtact ttgaaggata ggatatttct
    26281 ttttttatat cgatttgttc gattttttgc tggaaatcat ctggtcgggc atatacttgt
    26341 tctttttcac ttgtgtcaaa ttgttttcta acaagcaagc taatcggctt tggtgtgatt
    26401 tgattaatca aaaatacagt gactaaaata actacgatga taactggtac tgcaatcact
    26461 attcgcttga accatttcat tcatttaccc tctctttctt cgccaaatcc atgtgataat
    26521 cgtgctaaca gataaaaatc cacctgaata aatgagaagc gaatgtttct tttctccagt
    26581 tttcggcaac attctttttt ttgcatctgt ctttttttgt actttcactg tcatctgaat
    26641 cggttgcgta tcatcacttg attgatcctc tcgaggttca ttctttccct tattgtctgc
    26701 attctctgtc ggatcttgct tttttggtgg agctactggg atttttttgt aatagaaaat
    26761 aatagttggt atcgtctcat taaaaatccc ttcagtcggt ccttcaacat ttgctaattc
    26821 gtatccttcg aatgtctttt gctctgtcat ataattttct ccataagctc cgtaaagctg
    26881 gatttcgtcc tggtctttga gtagactttt attgttttca tccacatact ttacgtttat
    26941 ctgatcatgg aacactactt tcaaaaagtc cgttacatgt ttcgtgtagg cagcatggtc
    27001 aacttcctgt gcctttccat gccctgctcc ttctactaat aaaagatctt tataccctcc
    27061 tgataactca tataattttt gcgcgttaga cacaggtact acatcatctg ctgttccatg
    27121 gataatcaat ttaggcaatg aatctgacat tccaatcgta ggtagagcag cttttgtaac
    27181 caaatgcatc tcctgatcaa aatagtattg tttcaaaagg cccataaata aatcttcatg
    27241 ctcttgatcc ccaatgatgt ctaactgatt ttttatggca tccggtagtg cgggggctac
    27301 tgtctggctg tacgtaaaac gtagttgttc atcaattgat gcaaatccgc aattttcaat
    27361 aattcctttg acattgacag gaatatcttt cgctaataca gacatcatcg tagctgctcc
    27421 catcgaacca ccataaagta aaatcttttg agatggccgc tctcgaactt cttgatttat
    27481 ccagtaaagg acgtcatctg actcatattg tccataggtc acataatcgc ctccgctatt
    27541 accagtcgct ctggaatcaa caaataataa attatacccg gccttataaa aatcattgta
    27601 ttcttctgta acgatcccgt tattccaatt ccctcgaaat ccgccatgga tcatgactgt
    27661 tttatctgaa ccttgatcga cataatatgc atatacatcc atcattttgc catcttgttt
    27721 gtttagtaca gtttgatgaa gttgttttgt atttggatag aagcctgtgt tttctgtagg
    27781 cgttgtccca tcatctgtac ctccaagcat cgacatcaac acactgtttt ttgcaaaagc
    27841 gatatcgtac aatagataag tagcaatcag atgtttgata atctctttat ctacaccata
    27901 atcattaaca gcaagctcag tgactaataa ctctattaat tttgacttga tgtcttctgt
    27961 tggtccatta agtatttctg tcatctgttt accgaagtaa ttcaaatatt ctttaccatt
    28021 gaaattttca cctttaccga tatcatcatt ttctgtccca ttctctttgt cacttacttt
    28081 agcagaagag gattcgtcgt ttgacatttt tgtagctgtt gcttcttctg tttgttggtt
    28141 atctgtggta gcggtcgttt cttgatctgt gctagtaaca gatgtctcaa ccgttgtttc
    28201 agtatttgtt tctgtttgtg aagtactcga tttcgtttca tttccagcat cagtagtttc
    28261 tgtggtttct acctcccgag attccgattc ggaagaaatg ctctctccat atactgtcca
    28321 ttgcgggacg cttgtactta cagcaaataa gatgaccaac gctcccttta atacttgttt
    28381 tgttctcaag ctattcactc ctttttatgt ttctaggaga attatatgta aacgcaaaca
    28441 ttttttatac aaaaaataaa tggtttatcc cataaaaata gaacaggatt attttctcat
    28501 tttacgtaat aaagcagaat ggataaacca gtatccattc tgcttttttt aaacgaagaa
    28561 acaacttatt gctccaaaaa tgtcagaaat cgtttatccc aaattttctc gtaaaaagcg
    28621 attgtttcct ttgctttcat aaaaggatta tcataagttg tcgttgctcc tctacacatc
    28681 ataagctggt atcctaatcc atgagcaaac ttcacagtcg tatctataca atactctgct
    28741 tgtgccccac ataattcgat cgaatgacag tccaattcag ttaataaaac actcaaatta
    28801 gtcttataaa atgaattcgc atgggttttt ctcacaaaat aactgtgctc aggaatagat
    28861 aattccgaca atagctccca tggttttgtt tgtggcacta attgagcatc ttcgtgttga
    28921 acgaaaataa ctggtttccc aatcgtttcg tatgttttga ttcttttatt cactaatgct
    28981 gtcactgttt ctaattcgtg tatcggcgaa gaatcaaaac ataccccttt ttgtaaatcg
    29041 atcactacta ttgcgtcggc tgtgtttgac atacttgtgc cttctttctt ttttcttgat
    29101 ttaatagtat ttcttatcta gctagttcca ttatacgtga caacattttc ttattttaca
    29161 cctctaaatg gcacttttcg actatttctt catgttatta tttcataaat acttagctat
    29221 tggaggaatg tatgatgatt aaattgtata caggttctgg ctgctcgtct tcaagacgcg
    29281 caaaacgttg gcttatcgtc catgatatac cgtttatcga acagaactta attcgtcaac
    29341 cactaaccaa aaatgaattt atccacttac taaaattgac aaacaacggc gtgaccgaaa
    29401 tgctctctac tcattctatt agttataaaa atcttgttca cagaatagat gaactcagtt
    29461 tgagtgaact atatattgag attcgtacat ccccttcttt attgaaaaaa ccgattatct
    29521 acgaccaatc tgcaaaactt ttgactggat ttagcgaaga taaaatcagg atgttccttt
    29581 ctaaaactaa aagaaagcaa gagctcaacg aactcttgct ttctggtcat cttgtcgatt
    29641 ttaaagaaaa taatcttttt gcaatgtctt aattttggca taaacaatct gcttttctta
    29701 attaacgaaa tccaattttt ccaatatgga tctatttttc tcattcctga tttttatgat
    29761 ttcagctttc agacgcgccc aatcattttt tgtaggttgt ccattccagt aaaatatctg
    29821 tgtattcgtt tgatcatatg cctttttgtc gataggataa tcgctaatga caatatcagg
    29881 taactgatca gcggatgcac tatattttat tgggcgttca gtcatagata atatcctttt
    29941 ctttgcccat aattcctgtg ttttaccata ctttgattga atatagaata tgacaggttg
    30001 ttcgtgtttt ataaaaatat ccctgactaa catacagtat tgaaaaatca accgtctgtt
    30061 cttttcataa taagtattaa gctctggaat tctgcgagct accccactaa aaaactgttg
    30121 catgattgga tacatcactg gaaatatatg ctgaaaatct ctgtcttctg ctgattttcc
    30181 aaaagcatcc accttctttt ttgtcccaaa aacccttgaa tacaaatgga tcattgccaa
    30241 attgacatat agataatttt tttctgaagt tgtaaaacaa atcttgaagt ttttttcaaa
    30301 attttctaca atagacgatt caatccagcc ccaactttct tgtactttat ctggagtatc
    30361 caacaaatct tcttccaaat aggtgttcat tacaccaaac ataaaataaa ggtaagcttg
    30421 ctctgttgga gtgatgtgat tcatcgacca gaagtttgct tcaaaaaaag gctctagtat
    30481 gtaatgcgta aactcttctt ttgttatcaa tggatgcaca aatttgttca tctcttctgg
    30541 gacatacgta atcgagtggc cttgtttcat tcgttgcaac gaaattctta gtaggctgat
    30601 ccatttcttt ctatctatac tacgcgtata tggcgcatgt ttcgcaaatt tttctaatag
    30661 ttgacgttta ttttttatac ttgataatat atcagaatga ttttcgtcga atgactgcca
    30721 atacatcaag tgaaaaaagt atcggatacg gtattcttct ccttctatcg gattaccttt
    30781 tttcaagctg caagataaat gatagttttt caaaatagta ttaagttctc ttaattttct
    30841 ttgaatcgta cgcaaactta tataattttt tgactaagat tttctaagga ttgataagta
    30901 cctttgtaaa gtgaatccag taaaatataa ccaatcgttc cctctaaaag tatagaataa
    30961 actttactca gtaaaaactg agaagaaaac tcgactttta tcatcttgtt ttctgaaaga
    31021 aaagataatt tatattctgg atacctttcg caaaacgatt ctgcttgttg aatcaccgaa
    31081 ttcatcttag ccagggtgta gtttagatct aaagcgatat ccttcaccac atataatttc
    31141 tcgtctcttt cataacaata gttcaaaaat tgatatactt gcctttcatt gatatcaata
    31201 aattcttcaa acaaagtaca tactcctttt tatctattat ttagacttat tccgacagct
    31261 acatgaataa cgtacaaata gattcgttac tgatttttca gagatactac catgcgcagt
    31321 gtgcattgtc aattattctt gctcttattt tccatttgtg ttcctgttat ttcctgtttc
    31381 tcaaatatgt tagtaaacaa aaatagatct ggcaaagcta caacttcgcc aggcaataca
    31441 gcactctcga atgaaatatt cactcaaaaa tctatcgttt tattcaattt tagatctgtt
    31501 gcttttattc tttatttcac tcgatggaag agagaacgaa aatagcttgc tcctacaatc
    31561 aaaatgagta acacacccat ccatgtaatt agcttgttca aggttctact accagtttct
    31621 ggtaaatcgc tttttctatt atctgtttct ttcgcttttt cttgatgatc aattccacga
    31681 gaaacaaaat caggctgttt tagcacactt tttaggttgc tccctgcatt tctcttttgt
    31741 tccttagttg gtatgatagg taccaaatca agttcattat ttacttttcc tgtgctgctt
    31801 tcgctgctcg tgcttcctgt gctactctca ctactcatgc ttcctgtgct actttcacta
    31861 ctcgtactct ccgtactgct ttcgctgctc gtgcttcctg tgctactttc actactcgta
    31921 ctctccgtac tgctttcgct gctcgtgttt tctgtgctaa tttcactgct cgtactctct
    31981 gtactgcttt caccgctcgt gttttctgta ctgctttcac tacttgtgct atccgtactg
    32041 cttggcggtc caacaactgt ccaactgctt ggtttcaaat tctccgtgat cgtcatctgt
    32101 ccatcataaa aaacaatcaa atcaacttta tctttactct tgatctcatc aatcgatagt
    32161 tctgcagaaa tcattattgt atactcaata ccagcggtcc attgtacgtc ttttaaataa
    32221 acttccccaa taactttttc tgaacttcca ttaccatccc aaccatatgt tagaacagca
    32281 tgtacatcac tagcattcac gcttttgttt ggtttgactg gaatagtaat gacttgttgt
    32341 gtcatgtcat aaacaatccg atcagttttc acagtaaatg aaagattctc atttgcccgt
    32401 tcatttgcag aagtactgat tccaatcatt gctgcaatta tactcagccc aagaataaca
    32461 aataatacgg tcgctgtttt cttcatttct atcactctcc atataattac cttctatttg
    32521 ataaaggaat tatataaaat gaaaatgatg agaacacgac agtcagttgt gaaaatctaa
    32581 caaaagatgt cgtgtattcg cttgaatttg tttacttttt cgtttaatca atgacagact
    32641 taaaaaagca agaccgatat cagccttgct ttcttcatct tttattgata aacagcagtg
    32701 tatttcttca tccgctttgt tttatatgca tagagtaaca aaccaacaat caagactaac
    32761 aagaataatg tagttgatat agatgcttca gccccaaagt ttcccccagt aattattgta
    32821 ttttgcgatt ggatcagagt ggagaaaaaa ccttgttctt gcgttccgct gactggtata
    32881 cccaaaatag ctccttgtgt ccaattccaa gtaatatgag caccaatagc cgtaaataaa
    32941 cttcctgtac tgtagataag tgcgctgaaa aagcaacctg ctaaaaagat attgaaaact
    33001 gccagaaatg tcatgttagg attcaatccg tgcaaaagag caaataatgc agcagatcca
    33061 atcattgcta ttaacggacc aaatctaagc atctgatgct gaaaaaagcc acggaataaa
    33121 agctcttctg atgcccccac tgcaataaat aaaataaaac tcgttatcag cggcacaatg
    33181 tttgcgtttc ctgaatctaa ccgatacgcc cccgtcaaat ataatggact agtaataagc
    33241 agaaacactc caattccaac aacgagacct cccgctaaat acccccagtc ttttcctcga
    33301 acagaaacac cataatcttc tattcttttt ccttcgacct tactagcaag aaataaagct
    33361 agtaaaaaaa cagctaaatg tccgaccgta ccggcaattg ctccaatcca ttcactattt
    33421 ccaataaaca tatccgcaag tgcattattg acaagaattc ctaaaacaaa accaacaaag
    33481 actattaaaa cagatccaat caaccgaata atcctgatca tctttcatcc ctcctttata
    33541 ttaagtttaa caaccctttt ctttcttgtc tcgtgaaaac tatgtaaatg ttctccatca
    33601 tagagagaat agatttttac gaactaagaa tatctacagc aaccttacga aaatgaaaga
    33661 ctgtctccct aattcttctg ttagactgtt tttaataagg aaaggatggg aaattttttg
    33721 aaaaaacaac tactaattat gtgcctttca gcatgtgcaa ttttactatt ctcaggttgt
    33781 agcaagtcca atgaaacgat tgcaacgttt aaaggtggaa cacttacagt tcaggatttt
    33841 tatgataacc caaaagttaa atcaaataat caaacactat taaaaaaaat gattgtcttc
    33901 aaagcatttg atgatgtata cggaaaagag atttcttcaa aggaagtaac aaaagaatat
    33961 aatgaacaaa tcaaaaaact cggtccaaac tacaaggaac aattaaaagc agttggccaa
    34021 acagaagaga catataagaa actctttaaa cagatgctgg ctttccaata cggtttgaaa
    34081 gccaatgtaa aattaacaga taaagatcta gacactgctt ggaaagaatt ctatccagaa
    34141 gttagtacac agatcattct attttcgact aaagaagaag cagataaagc aaaaaaagaa
    34201 gcaaatgaag gagaaaattt ctccaagctt gttcaagctt atggaaaaaa taaaacatta
    34261 aaggaaactg atggaaaaat gaattttgat tcaaccaatc cagagattcc tactgaagta
    34321 aaaaaagcag catttaaact aaaaaacggg gaagtttctg atatcattcc tgtaacagat
    34381 ccaacgactt atcagcaaag ctattatcta gtaaaaatgg taaaaaaaca ggataaaggt
    34441 tctaataaag acaaatacaa atctgagcta gaaaaaattg ctaccgaagc aaaaactctt
    34501 gatacggaat tcatggataa aacaatccgt aaagtgatga aaaaagacaa tgtaactatt
    34561 aaagatcctt atgtaaaaaa tatattcaaa taaacaaatt tgacccaatt ggggatgtgg
    34621 caaaatttga gaagtgattt ttggaaattc cttcttattt ttgaggcaaa ccacttttgc
    34681 cacaacttca tcggggcctt tttttatttg taccaaaaca aatcactgga tttgttacaa
    34741 tcatgaggat ataatttaaa aaagtttttt atttctatca catgaatcaa tgcgccatta
    34801 agtagattct ttcatgcttc cctatttttt cacttgccgt atcgcttcaa aaacaactat
    34861 cataaactca aactcgactg aaaagttatt ttaaaaaaga ctaaaaatat cccttctgga
    34921 cttgttcttc ttattctgtt atactagaga aacacgaaag atatttttat gcgacacttt
    34981 tcatttgttt ttatgaaatt tattcaaaac tggcgtaact tcagagttac aaggatgtat
    35041 tagaggttag ggaatacatc gtttaaatga gaaataagta atagttagta atagtcaccc
    35101 aaactttaaa ttaatgaata ttgaatcgtc agatagcctc ctcgagtttt cgagaaggct
    35161 atcgtttatt ttatggagaa attgattcag aagtaatcag cgaccttttt tagttcacca
    35221 atcgtttctg cttggaaagt ttgcacccaa tcttcttgga agcccctcac tgctttatca
    35281 atcgagggca tctctaatac ttgatctagt agctctttac ctaacgttat cgctgagctc
    35341 cagatcgaat ggctgtagtg acttgttcac aatttttgaa actagctgct aatatttttg
    35401 ttggtctttg cgtacgttcg atctcagtcc gcaacgaatc aatcactttc atagcatcaa
    35461 tgccttgatt ttgcatcctg ttataataag gtgcaatata atctgctcca ttattaatag
    35521 ctaaataccc ttgtaattct gtgtaaatag ctgtaccggt aatcaaataa ccttcttttt
    35581 tcaacttttt gatcgcttga aggcctgctt gattcaccgg caccttgata aacgtatctt
    35641 ttcccagttc ttctatgata actcgagcat cctctatcat ttcttcttcc gttcttccta
    35701 ttgtctgaat atggatagga atctgtccga ttattttttt gatttctttc atatgcgaga
    35761 agaagtttga cgctccttct tttttcagaa ttgtaggatt tgttgttacg cctgttaaat
    35821 tcaaaaactg ttgacaagaa taaatacttt ttgtatttgc tgtatcaagc atgatttcca
    35881 tatagctttc ccccattctg atcctcttga tcgattttaa tgattgtccc ctttcttaaa
    35941 tgcggcattt ccttatcttc tacatacatt gttcctggaa gttccggctc atgagatcca
    36001 tcaaatttta tcgtgatatg tcctaattca ttcaaattag tttggacaac atctcctact
    36061 gctgtgatta catacatttg tttatcaaaa cagagcttca tatcacaagt tatttctttt
    36121 cttacctgat tcaattcaat cttataacaa taatctgtta atgtttccgg tgcttcatct
    36181 ccaaataaaa tcattatttt ttctttcctg aatacttctg cttctatacc aacatctgtt
    36241 acaaccgttt caaagatcgt catctctgtt cctcctcgta aaatatcatt tgtctaatag
    36301 tttttattca aaatgtttct agattataaa atttattgaa taacacattc ctaacggaat
    36361 ttgtttcgat attgtgtgat ttctcagagt acaatggatg tatgga
//
LOCUS       DASHXG010000026        34662 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.026, whole genome shotgun sequence.
ACCESSION   DASHXG010000026 DASHXG010000000
VERSION     DASHXG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.026"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(313..2205)
                     /locus_tag="U2R59_001482"
     CDS             complement(313..2205)
                     /locus_tag="U2R59_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965877.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="U2R59_001483"
     CDS             complement(2202..3929)
                     /locus_tag="U2R59_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965878.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="U2R59_001484"
     CDS             complement(3945..4595)
                     /locus_tag="U2R59_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HEM8965879.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="U2R59_001485"
     CDS             4799..5095
                     /locus_tag="U2R59_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEM8965880.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="U2R59_001486"
     CDS             5287..5907
                     /locus_tag="U2R59_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HEM8965881.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="U2R59_001487"
     CDS             complement(5999..7165)
                     /locus_tag="U2R59_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8965882.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="U2R59_001488"
     CDS             complement(7177..7530)
                     /locus_tag="U2R59_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEM8965883.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="U2R59_001489"
     CDS             7658..8680
                     /locus_tag="U2R59_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEM8965884.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="U2R59_001490"
     CDS             8699..8860
                     /locus_tag="U2R59_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965885.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="U2R59_001491"
     CDS             complement(9119..9553)
                     /locus_tag="U2R59_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965886.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="U2R59_001492"
     CDS             complement(9663..11522)
                     /locus_tag="U2R59_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8965887.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="U2R59_001493"
     CDS             complement(11640..12800)
                     /locus_tag="U2R59_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HEM8965888.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="U2R59_001494"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="U2R59_001494"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HEM8965889.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="U2R59_001495"
     CDS             complement(14547..15245)
                     /locus_tag="U2R59_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEM8965890.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="U2R59_001496"
     CDS             complement(15202..16863)
                     /locus_tag="U2R59_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HEM8965891.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="U2R59_001497"
     CDS             17081..18481
                     /locus_tag="U2R59_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HEM8965892.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="U2R59_001498"
     CDS             complement(18733..19812)
                     /locus_tag="U2R59_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8965893.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="U2R59_001499"
     CDS             complement(19898..20857)
                     /locus_tag="U2R59_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HEM8965894.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="U2R59_001500"
     CDS             complement(20869..22380)
                     /locus_tag="U2R59_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEM8965895.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="U2R59_001501"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="U2R59_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(22972..23835)
                     /locus_tag="U2R59_001502"
     CDS             complement(22972..23835)
                     /locus_tag="U2R59_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8965896.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="U2R59_001503"
     CDS             complement(23849..24745)
                     /locus_tag="U2R59_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEM8965897.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26209)
                     /locus_tag="U2R59_001504"
     CDS             complement(24920..26209)
                     /locus_tag="U2R59_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEM8965898.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="U2R59_001505"
     CDS             complement(26181..27698)
                     /locus_tag="U2R59_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HEM8965899.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27896..28786
                     /locus_tag="U2R59_001506"
     CDS             27896..28786
                     /locus_tag="U2R59_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEM8965900.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRSKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="U2R59_001507"
     CDS             complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="U2R59_001507"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEM8965901.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29695..31167)
                     /locus_tag="U2R59_001508"
     CDS             complement(29695..31167)
                     /locus_tag="U2R59_001508"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEM8965902.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31804..32166)
                     /locus_tag="U2R59_001509"
     CDS             complement(31804..32166)
                     /locus_tag="U2R59_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEM8965903.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32389..33141
                     /locus_tag="U2R59_001510"
     CDS             32389..33141
                     /locus_tag="U2R59_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8965904.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33281..34204)
                     /locus_tag="U2R59_001511"
     CDS             complement(33281..34204)
                     /locus_tag="U2R59_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965905.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34219..34491)
                     /locus_tag="U2R59_001512"
     CDS             complement(34219..34491)
                     /locus_tag="U2R59_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965906.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10232 a         7213 c         5978 g        11239 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa
    27841 cttttattaa caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca
    27901 actacaaata aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat
    27961 caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact
    28021 tggagtgagc agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat
    28081 caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat
    28141 cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg
    28201 tcactataca aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat
    28261 cgggaaagtg gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct
    28321 ctggtttacc agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac
    28381 attggagatg ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa
    28441 ttggccttca gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc
    28501 tggagatttt gctgatatcc gcagtaaata tacgcctgat tggtatccag ataatcttaa
    28561 tcaatacggc ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga
    28621 acccttgtca aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg
    28681 aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt
    28741 cggtaattac gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct
    28801 attttataaa acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt
    28861 atttccagaa atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc
    28921 accatgcttc gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat
    28981 caatttcatt atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt
    29041 caagatctgc agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca
    29101 attgtttccc ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac
    29161 caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc
    29221 ctgctctttc tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc
    29281 ctttgttaaa atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa
    29341 cagctggttt gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt
    29401 ttgcatcttc ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt
    29461 tttcatcttt tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta
    29521 aagtagaatc ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt
    29581 tcaaatatgc tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg
    29641 gtttgacacc taattcattg ataatttctg tctgcaggct catttattct cctcctatgc
    29701 ttctgtatga agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt
    29761 ccagcattca gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc
    29821 ttcccatagt gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa
    29881 ttcgtaaact ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc
    29941 tcgaacagtt ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc
    30001 tcgagggtct tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg
    30061 agtgatgcgc cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa
    30121 cttgatcgta tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc
    30181 accaagggct ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat
    30241 tttagctttt tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata
    30301 gatttttgct tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata
    30361 ggccatatct ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt
    30421 cgccacgcga atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa
    30481 cacgcagtct ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga
    30541 ttggactaac gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg
    30601 tacattgctt gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc
    30661 atccagttct tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga
    30721 tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc
    30781 tgtttctact aattggcagt gcgctaaagg cccttccact tggattaatg gttcatttgc
    30841 aaaaactagt tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa
    30901 atactccaaa aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc
    30961 attgaacgtc agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta
    31021 tccgtggtta aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg
    31081 acctaattcc cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa
    31141 actgtcgtct gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc
    31201 ctacccatta taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag
    31261 cacatgtttt acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc
    31321 ttattggtat ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac
    31381 gaagaaatta gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca
    31441 atcgtagccg ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa
    31501 tcaatggcaa aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa
    31561 agaaacggat ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat
    31621 ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag
    31681 taagaaagca gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc
    31741 ttgtttttta ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg
    31801 ttattaaata gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg
    31861 tttgaattgt attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc
    31921 ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt
    31981 tttcttcgta ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg
    32041 tgttcgatct aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc
    32101 cactacttta ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag
    32161 cttcatctca ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc
    32221 atctttccta gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc
    32281 ttttatcact taatagtata acataatttc gtgagaaaaa aatacaattt tttcttgacc
    32341 atctcgttac gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca
    32401 ataaagaaaa tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag
    32461 attggactgc taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa
    32521 gaagtcgatc gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat
    32581 atccaagagg tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag
    32641 caaatgttgc tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca
    32701 cttgatatgt acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa
    32761 caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga
    32821 aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa
    32881 gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca
    32941 gaagatgaaa gcttagcaga ccgtatcttc caagctcata agaagtggtt ctcttacagc
    33001 tggcctgaat atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa
    33061 cggttcactg catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa
    33121 attatccaaa aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga
    33181 cctaataaca aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct
    33241 ccattctttc acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat
    33301 aaggtatttt cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc
    33361 aagcttccag atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat
    33421 cgcgtccaat caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa
    33481 ccatatccga atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt
    33541 gttttccttt ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa
    33601 aaagttgatg acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc
    33661 ccaacgtgat gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa
    33721 ttgattgttc tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa
    33781 aaactagagg tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg
    33841 taatgatcaa tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt
    33901 ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa
    33961 tgatcccact gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa
    34021 tgcttttcgt ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt
    34081 ctttcatgac cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga
    34141 ttacacgtga aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg
    34201 ccactgctgc ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg
    34261 accgcattca aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc
    34321 ccaatatata tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt
    34381 cctattcaac ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc
    34441 ataaaaataa ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc
    34501 tccttttgat actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg
    34561 ccaaagaaaa gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata
    34621 cattataatg atactgtaaa tatatcttta ttattagtga at
//
LOCUS       DASHXG010000027        33263 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.027, whole genome shotgun sequence.
ACCESSION   DASHXG010000027 DASHXG010000000
VERSION     DASHXG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.027"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(41..229)
                     /locus_tag="U2R59_001513"
     CDS             complement(41..229)
                     /locus_tag="U2R59_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEM8965907.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="U2R59_001514"
     CDS             499..861
                     /locus_tag="U2R59_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8965908.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="U2R59_001515"
     CDS             913..2595
                     /locus_tag="U2R59_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEM8965909.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="U2R59_001516"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="U2R59_001516"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEM8965910.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="U2R59_001517"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="U2R59_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEM8965911.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="U2R59_001518"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="U2R59_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEM8965912.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="U2R59_001519"
     CDS             6430..7434
                     /locus_tag="U2R59_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965913.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="U2R59_001520"
     CDS             7435..8379
                     /locus_tag="U2R59_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8965914.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="U2R59_001521"
     CDS             8379..9341
                     /locus_tag="U2R59_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965915.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="U2R59_001522"
     CDS             9368..10282
                     /locus_tag="U2R59_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8965916.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMETNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="U2R59_001523"
     CDS             10308..12089
                     /locus_tag="U2R59_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8965917.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="U2R59_001524"
     CDS             12437..13123
                     /locus_tag="U2R59_001524"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEM8965918.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="U2R59_001525"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="U2R59_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEM8965919.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="U2R59_001526"
     CDS             16733..17542
                     /locus_tag="U2R59_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8965920.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="U2R59_001527"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="U2R59_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEM8965921.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="U2R59_001528"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="U2R59_001528"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HEM8965922.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="U2R59_001529"
     CDS             complement(21094..21546)
                     /locus_tag="U2R59_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEM8965923.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDSSILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="U2R59_001530"
     CDS             21696..22646
                     /locus_tag="U2R59_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEM8965924.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="U2R59_001531"
     CDS             22639..23598
                     /locus_tag="U2R59_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEM8965925.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="U2R59_001532"
     CDS             23595..24350
                     /locus_tag="U2R59_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8965926.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="U2R59_001533"
     CDS             24373..25326
                     /locus_tag="U2R59_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8965927.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="U2R59_001534"
     CDS             complement(25970..26266)
                     /locus_tag="U2R59_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HEM8965928.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="U2R59_001535"
     CDS             26621..26977
                     /locus_tag="U2R59_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8965929.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="U2R59_001536"
     CDS             26987..27886
                     /locus_tag="U2R59_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HEM8965930.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="U2R59_001537"
     CDS             28403..29134
                     /locus_tag="U2R59_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HEM8965931.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="U2R59_001538"
     CDS             29279..31306
                     /locus_tag="U2R59_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEM8965932.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="U2R59_001539"
     CDS             31414..32511
                     /locus_tag="U2R59_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HEM8965933.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="U2R59_001540"
     CDS             32818..>33263
                     /locus_tag="U2R59_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8965934.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11139 a         5761 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtgcttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggaa accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagaatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DASHXG010000028        32535 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.028, whole genome shotgun sequence.
ACCESSION   DASHXG010000028 DASHXG010000000
VERSION     DASHXG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.028"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            131..505
                     /locus_tag="U2R59_001541"
     CDS             131..505
                     /locus_tag="U2R59_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HEM8965935.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="U2R59_001542"
     CDS             complement(619..1248)
                     /locus_tag="U2R59_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8965936.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="U2R59_001543"
     tRNA            complement(1382..1454)
                     /locus_tag="U2R59_001543"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="U2R59_001544"
     tRNA            1668..1741
                     /locus_tag="U2R59_001544"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="U2R59_001545"
     CDS             complement(1879..2043)
                     /locus_tag="U2R59_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965937.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="U2R59_001546"
     CDS             2338..3666
                     /locus_tag="U2R59_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HEM8965938.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="U2R59_001547"
     CDS             3868..4701
                     /locus_tag="U2R59_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HEM8965939.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="U2R59_001548"
     CDS             4717..5454
                     /locus_tag="U2R59_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEM8965940.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="U2R59_001549"
     CDS             complement(5609..6577)
                     /locus_tag="U2R59_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEM8965941.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="U2R59_001550"
     CDS             6809..7642
                     /locus_tag="U2R59_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HEM8965942.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="U2R59_001551"
     CDS             7676..8515
                     /locus_tag="U2R59_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8965943.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="U2R59_001552"
     CDS             8541..9101
                     /locus_tag="U2R59_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEM8965944.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="U2R59_001553"
     CDS             9300..11021
                     /locus_tag="U2R59_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEM8965945.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="U2R59_001554"
     CDS             11186..12328
                     /locus_tag="U2R59_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEM8965946.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="U2R59_001555"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="U2R59_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEM8965947.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14777
                     /locus_tag="U2R59_001556"
                     /pseudo
     CDS             14128..14777
                     /locus_tag="U2R59_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="U2R59_001557"
     CDS             15170..17815
                     /locus_tag="U2R59_001557"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEM8965948.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="U2R59_001558"
     CDS             18125..19438
                     /locus_tag="U2R59_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEM8965949.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="U2R59_001559"
     CDS             19428..20081
                     /locus_tag="U2R59_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8965950.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="U2R59_001560"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="U2R59_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEM8965951.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="U2R59_001561"
     CDS             20978..21178
                     /locus_tag="U2R59_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8965952.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21432..23111)
                     /locus_tag="U2R59_001562"
     CDS             complement(21432..23111)
                     /locus_tag="U2R59_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEM8965953.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23113..23325)
                     /locus_tag="U2R59_001563"
     CDS             complement(23113..23325)
                     /locus_tag="U2R59_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEM8965954.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23718..25448
                     /gene="efrA"
                     /locus_tag="U2R59_001564"
     CDS             23718..25448
                     /gene="efrA"
                     /locus_tag="U2R59_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HEM8965955.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25445..27205
                     /gene="efrB"
                     /locus_tag="U2R59_001565"
     CDS             25445..27205
                     /gene="efrB"
                     /locus_tag="U2R59_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HEM8965956.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27300..27497
                     /locus_tag="U2R59_001566"
     CDS             27300..27497
                     /locus_tag="U2R59_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965957.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27650..28135
                     /locus_tag="U2R59_001567"
     CDS             27650..28135
                     /locus_tag="U2R59_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HEM8965958.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="U2R59_001568"
     CDS             complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="U2R59_001568"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HEM8965959.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29012..29539
                     /locus_tag="U2R59_001569"
     CDS             29012..29539
                     /locus_tag="U2R59_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8965960.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29630..30367
                     /locus_tag="U2R59_001570"
     CDS             29630..30367
                     /locus_tag="U2R59_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEM8965961.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30371..31288
                     /gene="miaA"
                     /locus_tag="U2R59_001571"
     CDS             30371..31288
                     /gene="miaA"
                     /locus_tag="U2R59_001571"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEM8965962.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31290..32519
                     /gene="hflX"
                     /locus_tag="U2R59_001572"
     CDS             31290..32519
                     /gene="hflX"
                     /locus_tag="U2R59_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEM8965963.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6876 g         9365 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg tatttttttg tatgaaaaag
    21301 taaataaatt taagaggcta tgaaagagcc accttgtatc aaggaataag aacaaacaaa
    21361 aatggcttct catgtttttc atttgttttc tcttatattc aggacaaggt gctgatttca
    21421 taacctctta tttattcttc atctggtgtc attaccattg gcaaaatcat tggatgtctt
    21481 tctgtacgtt cgaataagaa aggctgaagc gcgccagtca tcgcttcttt caatttatat
    21541 tctgaacagt caggtccatt caaacattct cttaaagcgt ggaataagat tcgctgagct
    21601 tcattgatca tttctcctga ttctcgcatg tagacaaatc cacgagagag aatatctgga
    21661 ccagccaaga tttctttttt cttgatatcc actgtcgcga cagctaatac aagaccttct
    21721 tctgaaagca ggtgacggtc acgtaaaacg acattaccaa tatcaccgat cccgctacca
    21781 tcgatataca catctccagc cacaaaatgc ccagcaggac gcgcagaatc gctagttaac
    21841 gctaaaacat cgccattttc catgatgaag cagttttctg caggaacacc tacatcttgt
    21901 gctagagaag catgtacttt caacatgcgg aattctccgt ggacaggaat aaaatatttt
    21961 ggcttcatca aacgaagcat taatttttgt tcttcttgtc caccgtgacc ggaagtatgg
    22021 atgttattga tttttccgtg aatcacttct gcaccagctt cagacagcaa attgatcaaa
    22081 tgattgacac ttgttgtatt accaggaata ggtgaacttg aaaagatcac tgtatcgtct
    22141 ggctggattt ggatttgacg gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct
    22201 tctccttgag aacctgtaca taggatcatc gtttcattgg caggcaagcg attgatttcg
    22261 tgtgcatcta caaatgtgcc gtctggaact ttgatatatc ctaaacgttg accgttgacg
    22321 atggcatttt ccatgcttcg tccgaaaaca gcgattttac gaccagttgc cacagcggca
    22381 tctgctgctt gctgcaaacg gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct
    22441 tcgatttttg aaaagatctt caaaatagaa tgcccaatcg ttttttctga tttagtaaat
    22501 gttggaatct cagcatttgt actatcagat aaaaggcaca agactccttc ttccccgata
    22561 cgagccattt tatgcaagtt tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct
    22621 ccagtcgcta cgatatttcc agaaggtgtt ttcaccacga tccctaatgc atctgggata
    22681 ctatgggtcg ttctgaaaaa gctgacagaa gtctttctaa aacggatgat cgtatcttca
    22741 ttgatctcat ggagctctgc atctcgaagc aagccatgct catctaattt gtttgtgatc
    22801 aacgctaatg cgagaggacc agcatagata ggaatatttg cttgtttcag caagtagggt
    22861 attccgccga tgtggtcttc gtgcccgtga gtaatcacca aggcttttac tttgtgtaag
    22921 ttttgtatga tgtagctgta gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc
    22981 gggaatttga tcccggcatc aatcaaaatg atttcatctt ggaattgtac cccatacgta
    23041 tttttcccga tttcacctaa tccaccaata gcaaagacgc ctgtctcgtt atttttgatg
    23101 gaaagtttca tattaaaact ccactaatga gaaatcagca ttttcttttt cgtactctag
    23161 atgacttcct tctagaagtt gaacgaattc aatattgtat ggggtatttt cttccacacg
    23221 ttggcgagcg tctacatcgc tttttgcctc aatgtaaaga gattttgttt cttcccgttt
    23281 agggttgcgt acttttgttt cttgataata aactttatag atcattgttt tgtctccttt
    23341 atctgcgtaa agcagtgatt tagctagttg atttttttag acaacacaaa acgaggggac
    23401 aagccacctg gtttttcata tgctttgact agaatactgg attcgagtca aagagacaag
    23461 cctcgttttt gcttatctgt tcggatattt tttcaaccgt accttctgta taaaaaatat
    23521 acaacaatta attgttattc tagcataaaa cagcaaataa gtatagaaat caactagatt
    23581 gaaagaaaaa atcaatgttt atcatcccgc tataatcata atgacttttt tatgagagaa
    23641 gtgttctatt aataggctcg ttgtgctatc atttttagta atgaaaatgt aacaaaagat
    23701 taaaaggaga tgagaaagtg aaactaatgt ggcattatac catgcgttat aagaaattct
    23761 tgtttttcaa tttcatatgc gtatttggtt ttattttgat tgaattagga cttcctacga
    23821 ttttagcacg tatgatcgat gtaggaatcc gcaatgatga ttttgattat gtgaagcaac
    23881 aagggatatt tatgatcgtt attactgtaa tcggtattat tttgaatatc ttgttaggtt
    23941 attttggttc gaggattacg actaatatcg tagcagatat tcgagatgat ttgttcgaaa
    24001 agatccaaag ttattcgcat caggaatacg aaaatctagg cgtatcttca ttgatcactc
    24061 gtacaacaaa cgatgcttat cagatcatgt tgttcctgca aaatatttta cgtatcggtt
    24121 ttatggcacc aatgatgttc attgtcagtt tgtacatggt catgcgtaca agtgtgacac
    24181 tcagtttgta tgtagtaggt gcattacctt tactattatt ggcagtcgta gcgattgcta
    24241 aggtgtctga accgttatct aaaaagcaac aaaaaaactt agataaaatc aacagtatct
    24301 tgcgggaaaa tctttcagga ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag
    24361 aaaaacgttt tgctgtagtc aatgagaatt atgcttctag ttcaaaaagc ttattccgtt
    24421 tgatggctgt tgcacaaccg ggtttttatt tcttatttaa tatcgtaatg gtattgatca
    24481 tctggagcgg ggcagtgcaa atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt
    24541 ttatcgagta tatattccat gccttgttct cattcatgtt atttgctagt gtgttcatga
    24601 tgtatccaag agcagctgtt tcagctggac gtatccaaga agccctagat gccaaacctt
    24661 cgattgtaga agatccaaat ggtatatctg atacaaaaac taaagggtat atcgaatttc
    24721 aaaatgtaac atttgcttat ccaggccatt cgcaagagcc agtgatacga aatgtcagtt
    24781 ttacagcctc tccaggagag accgttgctt ttattggaag taccggtagc ggaaaatcta
    24841 cgttgatcca attgatccct cgcttttatg atgtgagtga aggaaagatc ttgatcgatg
    24901 gagtagacgt gagagattat cggctaagca agttgcgaga taagattggg tttattccgc
    24961 aaaaagcgct gctatttact ggaacgattg cagataattt gcgatacggg aaagaagatg
    25021 ctacgcaaga agaaatggaa cgtgcagctg agattgctca agcttcagaa ttcatttctc
    25081 gaaaaccaga tggatttaat gaacatttat cagaaggtgg ttccaatttt tcaggtggac
    25141 aaaaacaacg attggcaata gccagagcca tcatacgccg tccggaaatc tatatttttg
    25201 atgacagctt ttctgcatta gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa
    25261 aagaaacgac agaatctact gtattgatcg tagcacaacg tgtgggaacg atcatgcatg
    25321 cagataagat catcgtatta aatgaaggag aagtcgtcgg tatggggacg catcgggagt
    25381 tgttggaaaa atgcccgatt tattatgata ttgccgcttc tcaattatca aaggaggaat
    25441 tagcatgaaa aaaacctttt cttccttaaa acgtttagct cgatatatca gaccgtatcg
    25501 tgagactttt cttttagtga tcctatttac agttctgaca gtggctttca acgtggcttt
    25561 gccatatgtt acaggacttc ctactacaga aatcagccgt aatattgcca atggcgaatc
    25621 aatcaatttt tcttatatat tcaaatgtct catttggatc acagttgttg gaatagggta
    25681 ttgtatttcg caattacttt ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca
    25741 tgatttgaga agagacatag aagaaaaaat caatcgtctt ccggtttcat atttcgataa
    25801 aaaccagcaa ggaaatattt tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc
    25861 tttacaacaa gcttttattg gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc
    25921 aatgatgttt tatatccagc cgatgatggc gctgatctct atgatcatga ttccaacatc
    25981 gatctggatc tcaaaacgag tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa
    26041 ttctcttggt gagctaaacg gctacgtcca agaaaatatg acaggtttta gtgtattgaa
    26101 agtatatgga cgcgaaaaag aaacattgga aggattcaaa aaagttaatc acagcttgaa
    26161 atactttggg tttcgtgcag cattcatttc tggcttgatg atgcctctag ttcaattaac
    26221 tgcctatgct acttatattg gtatggctgt tctaggaagc ttttatgtta ttactggggc
    26281 gatcgttgtc ggtcaactac aagcattcat ccaatatatt tggcaaatca gtcagccaat
    26341 ggggaacgtg acacaattgt cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt
    26401 attcgagatt ttagatgagc cagaagaaaa agaaaacaaa gtagatgctt cactgccaga
    26461 aacgatttta ggagatgtga cattcgatca tgtcgatttt gcatatgatc cgaagaaacc
    26521 attaatccaa gatttgaatt ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc
    26581 gaccggtgcc ggcaagacga cattgatcaa tctattgatg cgtttttatg acgtagacaa
    26641 aggagcaata aggattgatg gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc
    26701 gctatttggt atggtcttgc aagatgcatg gctttatcaa ggaacgattg cagataatat
    26761 ccgcttcgga aagcttgatg cgacagatta tgaagtagtt gatgctgcga aaacagcaaa
    26821 cgtagatcat tttatccgaa cgatgccaga tggatatgat atggccatca attctgaggg
    26881 agacaatgtg tctttaggac aaaaacagtt gctgacgatt gcccgagcag tggtctccga
    26941 tcctaaaatc ttgattttag atgaagcaac aagttcagta gacacccgtt tagaagcgtt
    27001 gattcaaaaa gcaatggatc gcgtgatgga gggacggaca agtttcgtca tcgctcaccg
    27061 tttatcgaca atccgtgatg cagatctgat tctagtgatg gatcaaggtc agatcattga
    27121 aaaaggaacg catgagagtt tattggcaca aggtggattt tatgaaaaac tgtataacag
    27181 ccaatttgct gaggaagcag aataagtcat ataagaataa aacagtttaa aacttatttt
    27241 ttgttctcta ttcttgataa tggtaaagta aagttatcaa gaaaagtgag gacacggaga
    27301 tggaacagtt tttaaatgaa aaaattactg aagccaaaag agaagttgat cgtttaacgc
    27361 acgtctgtca gacgaagcct tttgattcag ctgatttttt tgaaaatgag tttcaaatcg
    27421 aacgcttggc agcacaaata gaagtgtacg aattaatttt aaaaaaagta atagaagaaa
    27481 atatagatgt acaataaaaa caggtaaaac gtcagttacc agatactgta aatagacatc
    27541 tggcctgagc aggttttacc tgtttttttt cttatgaaat aaatatatgc tatgatacct
    27601 ttattcaata ggattagttt ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt
    27661 tatagcatca aatgccacag tgattggtga tgtgacattg tcagaagatg tgacgatctg
    27721 gtatcaagct gttttacgcg gggacagtaa ttggataaaa ataggacaaa gaacgaatat
    27781 ccaagatggt acaatcatcc atgtcgatca tgatgcacct gtagatattg cggagaatgt
    27841 gacggtagga catcagtgca tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg
    27901 gatggggacc acgatattga atcatgcggt tattggtgag aatagtttga ttggtgctgg
    27961 atcattagta acagaaggaa aagttattcc tcctaatgtc ttggcttttg gtcgcccagc
    28021 taaagtgatc cgtcctttga caaaagaaga aatacaaaaa aacaaagaaa acatccagca
    28081 ttatgtcgag ataggtcgga tgcatgcgca aggaaaattc aaggagcaaa gataggcagt
    28141 agcatccata aaataaaaaa ggatggtcag tttgagttga ccatcctttt ttatttggtt
    28201 tagataagag agcttaaaaa agcttccttt gaaacagatt aatttaatga agaactgttt
    28261 tccatgactt catcgatcaa tccatatgct tttgcttgtt cagctgtcat atagttgtca
    28321 cgatctgtat ctttttcaat cacttcaagc ggttgtccag tgcgttcagc taaaattttg
    28381 tttaagcgtt cgcgtgtttg caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc
    28441 ccttgagcgc cgccaagagg ttgatggatc atgatctcag catttggtaa agcaaatcgt
    28501 ttaccttttg taccagctgt cagcaagaag cttcccattg aagcagccat acccataaca
    28561 attgtttgga catctgcttt gacaaagttc attgtgtcgt aaatagccat acctgctgta
    28621 actgaaccac caggagaatt gatataaaga tagatatctt tttcagaatc ttgagcgtct
    28681 aagaaaagca attgggcgat gatcgaatta gcaagatcat ctgttacttg gccgcttaac
    28741 atgatgatac ggtctttcaa taaacgtgag tagatatcgt aagctctttc acctcgtgaa
    28801 gattgttcaa tgactgtagg aattaaattc ataatagagt tcctccttga tttcgtttag
    28861 aaatagtgta ccataattta gtttctaata cctaaaatgt agtatacatt tttggtcaaa
    28921 aaaggtcaaa taaaaaactt aggcaaatta gtcgcataaa cccgctttat ggtatgataa
    28981 gcagagaaac aaaacaagga ggaacaacag attgatagtt ggtattactg gccttatcgg
    29041 agtgctgaca ggtgctgtag ttgtctatat cggcatgata ctgcaaatgc gtcacttgga
    29101 aaataaagaa cagcgtagac gtgaattgga attgaaagtc aaagaaatcg agacgctgaa
    29161 tcaattaaat aaaaagatca acgagatctt gcaaaaacgg acaacgctga tggaagaata
    29221 tgtcagcttt gatgcatttg atgattgtta tatcacgatt gacgattttg cgtatctcca
    29281 atcattttca gcgcaaaata gtttttatct gccaaattat attttagacg agctatttaa
    29341 gaatatctcc catcgaaaag tgattttatc tccagatgaa acaatgaaga ttggtggata
    29401 tgcttataaa ggcggacgcg tgattttaga gaattttacg gatagtctga ctgaaatgat
    29461 caatgaaaaa aaagctcagt tgaagactat gacgcgccag ccgattggtt tcttctcgaa
    29521 agatgatgtt tggagctgat attttgaagc attgccgttg cacatgagag cgtggtaatg
    29581 ctttcttttt ttcttaatga tacaatagaa ctgaacggag tgaagaaaga tgttacaaat
    29641 ctatgcccat cgcggaagca gcggcaccca cccagaaaat acgcttcctg catttgcaga
    29701 agctgtacga gtaggtgcag atggtatcga actagatgtc catctaagca aagatggtta
    29761 tttgatcgtt atgcacgacg aagaagtgga ccggacgact aacggtaaag ggctgattcg
    29821 agaaaaaaca ttggaagaac tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt
    29881 tccagcagct aaagttcctg aattgagaga agtgttagga ctgctcctcc aaaaaaatta
    29941 ccgagggatg ctaatgattg aaattaaaac tgatcagtat gaatatcccg gtatcgaaga
    30001 aaaattagcc gaaacattaa aaagtagaga ttggcctttt caacatgcat attgcagctt
    30061 tcatttggat tctttggaaa aaatcgcatt actggaaccg gagatacagc tggacttatt
    30121 gatgagtact tctgataaaa agatccaact agcagcagaa accccttata tagaaggagt
    30181 acatccaaaa aatacttggt tgttcgaaca tccagtccag gcagctgatt ttccaaaagc
    30241 aattcgtgca tggacgatta acgatgaaga agaaatggcc aaatgtcaag aactcaaaat
    30301 agatggaata ataactgatt ttccggagaa agctcttcgg tggaaacaat caacgaaaag
    30361 taggtaaaat atggaaaaag tattagtgat cgtcggtccg acagcagtcg gtaaaacagc
    30421 gctaagtgtg gaactcgcac aactatttgg aggagagatc atcagtggtg attcattgca
    30481 aatctataaa aatctggata tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt
    30541 tccgcatcat ttgattgatg tgatcgaacc tactcaacgt tactcagccg ctgattttca
    30601 gcattcaggt cgacaattga ttaccgagat tgcgaaccga gggcacctac ctatcatagc
    30661 tggtggtacg ggtctctata tccaatccct tctatatgat tatcagttag gagcgacaga
    30721 agaagcgaat cctgagatta gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca
    30781 agcattatgg aatcagttga aagaaaaaga cccggcagct gctgagaaaa tccactggaa
    30841 caatcaacgc aaagtgataa gagctctgga agttttagag acgacaggac atagtatcac
    30901 ggcacctaaa gaagagccaa agcaattgta tgattacctc atgattggat tagatacgaa
    30961 gcgtagtatt ctttatgaac gaatcaatca aagagtcgat ttgatgctag cagaaggttt
    31021 agtagcagaa gcgcgtaagg tgtatgagct tggagaagtc caggccagtc aaggtattgg
    31081 atataaagaa tttttccctt attttgaagg gaaagaaaca ttggaagaag caacagaaca
    31141 agtcaaacta cattcgagaa gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt
    31201 ggatgcacag tggtttgatc ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac
    31261 aatcaaaaaa tggctggagg cggaataaaa tggaagaaaa agtgatcatc gtaggggtag
    31321 aaaccgaagc aaaccagcgt tacttttcag agtcaatgga agagctagtt cagctgacga
    31381 ataccgcatc aggagaagtc gtattcacaa ttacacaaaa gagaccacaa gtggatcggc
    31441 aaacgattat cggtaaaggg aaattacaag aattagttca acaagcggat gcgcatgaag
    31501 cggatttgat catctttaat catgagctaa ctccgagaca gagccaactg attaccgatg
    31561 ctgttggtct tccggtaatt gatcgcgtgc agcttatctt agatattttt gcgatgcgtg
    31621 ctcgttcgaa agaagggaag ctgcaggttg aacttgctca gttagaatac ctgctgcctc
    31681 gtttagtagg gcaagggaaa acattatctc gtcttggcgg tgggatcgga acaagagggc
    31741 caggtgaaac aaagttagaa acagaccgcc gacatatacg gaataaaatt tttgctgtta
    31801 agaaagaatt gaaagaagta gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata
    31861 gcgagatttt tcagattgga cttattggct acacgaatgc cgggaagtca actatcttga
    31921 atctattgac acaagcggat acttattcga aagatcaatt gtttgcaacg ttagatccat
    31981 tgactaagag atggcgtttt gctgaaggat ttgagattac tgtaacggat accgtcgggt
    32041 tcatccaaga cctgcctacg caactgatcg atgctttcca ttctacatta gaagaaagtc
    32101 aaaatatgga tcttttgcta catgtagtcg atgctagttc tccagatcgt attttacagg
    32161 agcagactgt cttaaaattg atggatgaac tgaatatgaa agaaatgccg atactgactg
    32221 tttacaataa ggcagaccag atcgacccag cgatgttcac gcctacgcta ttcccaaatg
    32281 tattgatttc tactcagacg aaagaaggta agatggcgtt gatcgaagca atcaaacgtc
    32341 agctgatgga actaatgacc ccttatacac tttctgtgcc aagcaacgaa ggacagaaat
    32401 taagcgagtt gagaagacaa acaatggttt tggacgaagc gtacatggaa gaaacaaacg
    32461 aatatgaagt taaagggttt gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa
    32521 attttatttt tttaa
//
LOCUS       DASHXG010000029        32501 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.029, whole genome shotgun sequence.
ACCESSION   DASHXG010000029 DASHXG010000000
VERSION     DASHXG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.029"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(513..2009)
                     /gene="lysS"
                     /locus_tag="U2R59_001573"
     CDS             complement(513..2009)
                     /gene="lysS"
                     /locus_tag="U2R59_001573"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEM8965964.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="U2R59_001574"
     CDS             complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="U2R59_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEM8965965.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="U2R59_001575"
     CDS             complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="U2R59_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEM8965966.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="U2R59_001576"
     CDS             complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="U2R59_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEM8965967.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="U2R59_001577"
     CDS             complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="U2R59_001577"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEM8965968.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="U2R59_001578"
     CDS             complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="U2R59_001578"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEM8965969.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8540..9010)
                     /locus_tag="U2R59_001579"
     CDS             complement(8540..9010)
                     /locus_tag="U2R59_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HEM8965970.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9056..9481)
                     /locus_tag="U2R59_001580"
     CDS             complement(9056..9481)
                     /locus_tag="U2R59_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEM8965971.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9548..9817)
                     /locus_tag="U2R59_001581"
     CDS             complement(9548..9817)
                     /locus_tag="U2R59_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEM8965972.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9828..11423)
                     /locus_tag="U2R59_001582"
     CDS             complement(9828..11423)
                     /locus_tag="U2R59_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEM8965973.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="U2R59_001583"
     CDS             complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="U2R59_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEM8965974.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14976..15536)
                     /locus_tag="U2R59_001584"
     CDS             complement(14976..15536)
                     /locus_tag="U2R59_001584"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEM8965975.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15889..16863
                     /locus_tag="U2R59_001585"
     CDS             15889..16863
                     /locus_tag="U2R59_001585"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEM8965976.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17033..18433
                     /locus_tag="U2R59_001586"
     CDS             17033..18433
                     /locus_tag="U2R59_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HEM8965977.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18511..19233)
                     /locus_tag="U2R59_001587"
     CDS             complement(18511..19233)
                     /locus_tag="U2R59_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8965978.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19312..19818)
                     /locus_tag="U2R59_001588"
     CDS             complement(19312..19818)
                     /locus_tag="U2R59_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEM8965979.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19941..21740
                     /locus_tag="U2R59_001589"
     CDS             19941..21740
                     /locus_tag="U2R59_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HEM8965980.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21808..23382)
                     /locus_tag="U2R59_001590"
     CDS             complement(21808..23382)
                     /locus_tag="U2R59_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HEM8965981.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="U2R59_001591"
     CDS             complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="U2R59_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEM8965982.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="U2R59_001592"
     CDS             complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="U2R59_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEM8965983.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25159..25797)
                     /locus_tag="U2R59_001593"
     CDS             complement(25159..25797)
                     /locus_tag="U2R59_001593"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEM8965984.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25798..26448)
                     /locus_tag="U2R59_001594"
     CDS             complement(25798..26448)
                     /locus_tag="U2R59_001594"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEM8965985.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="U2R59_001595"
     CDS             complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="U2R59_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEM8965986.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="U2R59_001596"
     CDS             complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="U2R59_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEM8965987.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29591..30331)
                     /locus_tag="U2R59_001597"
     CDS             complement(29591..30331)
                     /locus_tag="U2R59_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEM8965988.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="U2R59_001598"
     CDS             complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="U2R59_001598"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEM8965989.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31702..>32501)
                     /gene="fmt"
                     /locus_tag="U2R59_001599"
     CDS             complement(31702..>32501)
                     /gene="fmt"
                     /locus_tag="U2R59_001599"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEM8965990.1"
                     /translation="PVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQF
                     LPEKLLQVPKLGAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIY
                     AQESIPITKQDDVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITRE
                     QEAIDWHKTAEEIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKD
                     KKNLWIACGKQTVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
BASE COUNT         8822 a         7067 c         5943 g        10669 t
ORIGIN      
        1 tttttggctg ccgtagcaac ttttatatca tatcagagag acaagcgatt gtcaactctt
       61 ttttaaaagt ttttttcgat ttcgtttttc gaaatctttc ggcaactcat ttatcataac
      121 ttatcgtttg ttatttgtca agaacttttt tgaagttttt ttcgatagaa tcaagcttcg
      181 caagtggttc ttttttaacg actcagttat cttatcatgt cgttagtaac atgtcaataa
      241 cttttttgtt atgtttttga ataaatattt tcttctgtct tttggacaag taataatata
      301 ccaactaaat ttagcttggt caacgaattt tttgtatttt ttcaagtttt tttcaataaa
      361 cgattattca taacttttct ttctttatcg ttcgttttcg tcttctttaa tgtctagaat
      421 agtcggcatt agcttttgaa ctttcgttat tatttattcc tttctacaca gcaaaagctg
      481 cctaaggaat tccttagaca gcttttattc gattatctca ttgttgggaa tagcaaaaca
      541 tcccgaattg attgtgcatc agttagcaac attactaatc tgtcgatccc gatgcctaga
      601 ccaccagttg gcggcatacc gtattctaag gcttccaaga agtcttcgtc tacaccgtga
      661 gcttcgtcat ttcctagttc acgttctttt tcttgcgctt cgaatctttc tctttgatca
      721 attggatcgt tcagttctgt aaaggcatta gcaaattcgc gccccactat gaatagttcg
      781 aatcgatctg tgaatcgagg atcttctgga tttttcttcg ctaaaggcga aacttcgact
      841 ggatgtccgt atacaaacgt cggttgtgtc aatgtttctt caacaaatgt ttcaaagaat
      901 tcattgataa catgtccgac acccatagct tcggttactt ctacattgtg tttttcggct
      961 aaagctaatg cttcttccaa tgtcatttct tgccagaagt ctacaccagt ttgttctttg
     1021 attgcatcta ccatatggat gcgtttaaag tcactttcta agtcgacagc ttgtccatca
     1081 tatgtgattt ttgctgttcc tagtactttt tcagctgcgt tacggataat accttctgtc
     1141 agattcatta catcattgaa atcagtatat gctgtgtatg cttctaacat cgtaaattct
     1201 ggattatgtg tagtatcaat tccttcatta cggaaaacgc ggccgatttc ataaactttt
     1261 tccattccgc caacaattag tcgttttaaa tgaagttcta gcgcaatacg caaatataaa
     1321 tcaatgtcca gtgcattatg atgcgtgata aatgggcgtg cggcagctcc acctgcctca
     1381 ttgtgcaata ctggtgtttc tacttcaata tagccattgc catctaaata gcgacggatt
     1441 tcgctgataa tttggcttcg tttcataaat cggtcaaagc tttcgcgatt actgattaaa
     1501 tccaagtagc gttgtctgta gcgttgttca atattcgtta agccatggta tttatctggc
     1561 agtggacgaa gtgcttttga caaaatcgtg atttctgaag ctttgataga aacttcgcct
     1621 gtgtctgttt tcatgatttg tccagttaca ccaaagaaat ctccaaggtc tgcatgtttg
     1681 aatacttcat aggcctcatc acctacttgg tcttttctta cataaatttg aatttggcct
     1741 tcacgatctt gtagatgcgc aaatccagct ttcccttttc ctcggcgagt catcatacga
     1801 ccagctacac tagcggtcaa tcccatttct gctagttctt cttttgttct tggatcaaat
     1861 agttcatgca attcttctga gttgtgcgtg cgttcaaatc gttttccaaa tggatcgatt
     1921 ccatcttcac gcaattgttc cattttttga cgacgtacaa gcatttgatc atttaaatct
     1981 tctacttgat gttgttgttc ctgtgtcaca aaagttcctc cattctcatg ttaatctctt
     2041 tcctataatg ccaatgaaac acaaaaaaag caagccgaac ttggaatttc ggcttgaaaa
     2101 ttcacgaaaa acttagaaat cacaacgttt gtttcaatag tactttttcc gctttttcta
     2161 caaattgatc cagcaggtca ttgatttctt gctgtttttc tgtctgattg attgctactt
     2221 tcactttcgc tgctcgagga atccctttta aataataagc cgcatgtgtt ctgaattctc
     2281 tacaagctac tttttctcct ttgagatctg ctaagcgttg taaatgaagt ttagctgtag
     2341 caattttttc ggctggtgtt ggttcaggaa tcagttcccc tgtttcgaga taatgctgtg
     2401 tgcggtgaat catccatgga ttgcccagcg ctgcacgacc aatcatcaca ccgtctgcac
     2461 cgacatagtc aagcatccat tttgcatctt ctggcgtttt gacatccccg ttccccataa
     2521 atggaatcgt caaatgtttt ttcacttctt tcaatacttc ccagtccgct tttccttcat
     2581 acatctgaac ccgtgtacgt ccatgcatag cgatggcact tgctccagct gattgtgctg
     2641 ctaatgcatt ttctacagca aagacgtgct cttcatccca accaatacgc atcttgattg
     2701 ttactgggat atttactgct gaagaaacag cttggaccat ttcgtatact ttctcaggat
     2761 ctaaaagcca ttttgctcct gcttctgctt tgattacttt atttactgga cagcccatat
     2821 tgatatctat tatatcggca gctgtgtttt cttcgacaaa ttgagcagct tcaactagac
     2881 tatctttatt tccgccaaat atctgtaaac ttaatggatg ttctgtttct tcaatgtgga
     2941 gcatctctaa agtttttttg tttctgaaat gaataccttg gtcactgatc atttcacata
     3001 cgactaagcc cgcaccaaat tctttgacag tgactcgaaa tgctgaattt gttattccag
     3061 ccatcggtgc aacaacgaca cgattaggga tttccacatt gccaattttc catgtgtgtt
     3121 ccacttaaat ccctcctaag gcttctttct tcaatccatc taattcttct tcgctatact
     3181 tgtatttgtt attacagaaa gaacaaaccg cttctgcacc gtgatcttcg tctatcattg
     3241 cttggatttc ttctgcacct aacgcgataa ttgcttctgc aaatttttct tttgaacagt
     3301 cacatttgaa ttgaacaggc attttttcca aaatgttcaa ttcttctgta ccaagcaatc
     3361 ctttcaatat ttcttctggt gtctgtcctt catctaagag ggtagagatt cttggtgtcg
     3421 tttttaattg ttcttcgatc ttgctgattg tttcttcatc ggcacctggc atgatttgga
     3481 tcatgaatcc tcccgccgtc ttgatgctgt cgtcagtatt gaccaataca ctcagtccaa
     3541 cagctgaagg gatttgttct gagatagcaa gatagtaagt aaaatcttca gcgatttctc
     3601 cagaaacaat cggcgtttgc ccagaaaaag gttcttttaa tcctaagtct tttgtgacag
     3661 taaacattcc ttgtgttcca actgctcccc gcacatcgat tttaccttca ctatttagag
     3721 gaagactgag atgcggattt ttgatgtaac ctttcacatc tccctttcca tttgcatcta
     3781 ctacaattcc tgttgctgga ccatcgcctt ggattcgaac agttagtttg tcttctcctt
     3841 tgagcgtcgc accaagtagc agactaccga ccaatgtccg tcccaaagca gctgaggagg
     3901 tgtgccaagt atcatgacgt ctttgtgcct ccgctacggt atttgttgct tgaacggcgt
     3961 atgctcggac gaatccgtcg tgagcaagtg ccttaaccaa ataatctttc atttgttatg
     4021 tactcctttt tccgttttta aactcatagt gaatcatact agcaactact gcttttttca
     4081 actttggaat gcttctttta aaaataattc agaatcatct agaaaacagg acatcaccct
     4141 atttacaact taaataaaga aatctcccga aaaccggttt ttgttccggt tttcgggagt
     4201 catatcagat caattgacct atattttttt atttgtattg atcgtctgaa tgattatctt
     4261 ctgattgttg agaatctgaa tcatgttctg ctttattttc ctcattcagt tcatgttttg
     4321 cttcttcaaa atcacgtttt tcttccgctt gtttttcagc gtctttttct tccaaagcac
     4381 gttttgcttc ttcaaaagtt ttcgcttctt tttcgcttgg ataatcattt gactcagtac
     4441 cttcaggcat cacaccgtgt tcaaacaatg acttgattgc tttggcatcc aatgtttcga
     4501 attccaaaag tttttcagca atcagtttat gctgtgcacg atgagcttcg atgatttctc
     4561 gagctttatc atgagcttcc atcaagattt ttcgtacttc ttgatcaatc tcgaaagcga
     4621 cttgttccga gtaagctttt gtttgaccat agtcgcggcc aacaaacact tgatggtttc
     4681 cttcatattg aacaggacct aaacgatcac tcattccata ttctgttacc atgcttcgtg
     4741 ctagagctgt cgcttgctca aagtcattgg aagcaccagt tgattggaca ttgaagatga
     4801 tttcttcagc tgtacgtcca ccaagtaagc ctacgatttg ttcaaacata tcttctttcg
     4861 tcatcaagaa ctgatcttct tttggtaaag cgatcatata tccgccggcg cgtccgcgag
     4921 ggatgatcgt tactttgtgg acgacccgag cgcgactcaa tactaatccg acaatcgtat
     4981 gaccagcttc gtgataagca accatttcgc gttctttttt gctgattacg cgatcttttt
     5041 tagctggacc tgcaatcacg cgatcttccg cttcatcgat atcagaagca tcgattttct
     5101 ttttatttct tctagcagct actaacgctg cttcattcaa gacattttct aaatctgctc
     5161 cggcaaaacc tggtgtctgt tgagccacaa ctttcaagtc aacgtcatct gccatcggtt
     5221 tattccgtgc atggactcgc aagattgctt cacgaccttt tacatctgga cgtccaacta
     5281 aaatctggcg gtcaaaacgg cctggacgta gtaacgctgg gtctagtaca tcagaacggt
     5341 tggttgcagc aatgacgatt actccttcat ttccgtcgaa gccatccatt tctacaagca
     5401 attggttcaa tgtttgttcg cgttcatcat gtccgccgcc cataccggca ccacgttgac
     5461 gacctaccgc atcaatttca tcaatgaaaa tgatagctgg tgcgtttttc ttcgctgttt
     5521 caaacaaatc acgaacacga cttgctccaa caccgacaaa catttctacg aaatcagaac
     5581 ccgagatcga gtaaaacggt actccagctt ctccggcaac agcttttgct aataaggttt
     5641 tacctgttcc tggaggtcct tctaaaagta cacctgccgg gatacgggca cctaattcaa
     5701 caaatcggcg aggatctttc agaaattcaa caacttcaac tagttcttgt ttttcttctt
     5761 ccgcacccgc tacatcagaa aaacgtacgc gattagcttt tttgtctgct tctttggctt
     5821 ttgatttacc aaagttcatg acacggccgc caccgccacc gccgccgcct tgttgtccca
     5881 tcatcatgta aaagaaaaag atgatgatta cgattggcaa gaagctaagc aatagggaaa
     5941 cccatatacc gctgcttgat tcttctttta ctgttgtagc aactttgttt tcttttgcca
     6001 gttctgttac ttggctcaat gttgtatcat ttggcaaaat gattgttgtg aaatgggtag
     6061 tagtcgtatc tgttgaacct aagatagcta acccaccgct gttagcgacg gtctgctgtt
     6121 ctttgtattc accagtgatc ttatatacac catttgcagg ctgcacttca aattctttga
     6181 tcttgcctgc ttgtagttgt tctgtgaatt ttgagtactc gatatctgac gatcgctggc
     6241 cgttattacc aaaaatgaaa taaacgacca ttaccatcgc taagattacg aggacataat
     6301 acaaggcatt tttcatcatg ccgttgttct ttttgttcat agttgccctc cctaagcgtc
     6361 aatttaattt aacagttttt tatcaatcct gaccattcta ttgtaccata atttaattga
     6421 gatacagcat taatttgatt gataaacact aggtttcaat acaccgatgt acggaaggtt
     6481 acgatatgct tctgcataat ccaagccata accgaccaca aattcatttg gtacgttgaa
     6541 gccaacataa tctgcttcga tatttactac tcttccttca ggtttgtcaa gtagtgtaac
     6601 aattttgact gattttgctt tgcggtattt gaaaagatcc actaaataag caagtgttct
     6661 tccgctgtca atgatatctt caacgatcaa cagatcgcga ccttctacat tcgtatctaa
     6721 gtctttgacg atttttactt cccctgacga gactgttgca ttcccgtagc ttgaaacatc
     6781 catgaaatcc aattccaaat acgtatcgat agaacgaacg atatctgcca tgaatggtac
     6841 cgctcctttt aagacaccta ctactagggg attggtgttt tggtaaattt ctgttaactc
     6901 tttgcctagt tctttgcaac gaacttgtat ctcttcttgt gagatcaaaa ttctctcaat
     6961 atccttttcc aacatcaggt tctccttcca attgcttctt tttgatattt gtaaagaagt
     7021 atgtagtgta ttttatcagt ttcttcacga atactcaaat atgaaaaggc aaaaggtatc
     7081 aagctatata tatttctttt ggcatctgta atgatccaag catgctgcct ttgtgaatta
     7141 ggtactttct gatcgataaa atatctagat actttttttg tgagattctc tgttaattta
     7201 atgcggtctc ctgcttttct tttttcgaca tacagttgca catcagcagg aatccaaatg
     7261 tcatgagaaa atagagacca tgaatctgtt gctttgatgt cccctgcatt ttcaggtttg
     7321 accagaccaa tccattctgt ttcattcaaa tatattcctt gttctggaat cagcaacaag
     7381 cgctggtctt ctgtctggct agttgcttgt ttttcttttt tagagagtac aacaaaatga
     7441 tactctcttt tcagtatcca attattgcca atactgagtt gccattggct ttttttctgt
     7501 tgccactggt ctaaaatcga ctccatttgt tgttctttca aaataattcc tgtttttgag
     7561 aatgctttgt cgaaaaagga gtaaaaaaaa tagtatcgtt cagcatctgt catttcttca
     7621 atcatttctg cagaaaatcg aaattgttcc tcccactgtt cgacttcctt ttcgatcaac
     7681 tgtcccatat atttttgaat gacttggtct gcccattgga tctgttgcga aaattgctgg
     7741 aaatgtctca acgcctgtgt attttcttgt ttcaattgag gaactaccaa atgacgaagc
     7801 cgatttctct ggatatctaa caattggttt gtctgatcct caaagtaaac aagctgcgat
     7861 tccgctgcat aagtatatag gtcttctttg ctaaaactca gcaacggacg aatcagtctg
     7921 cccgtagcaa atggttgtac ttctttgatt ccagaaaaag tatttaactg tcccccacga
     7981 acgattttca ttaacaccgt ctcgatttga tcatctccgt gatgagcagt catcaacgtg
     8041 tcatattgtc cttcttccat cacgcgagtg aattcttgat aacgaaagtt acgagcttct
     8101 gtttctatgg cggatttggc tggatcttcc caaatactta catataaagg gagattcttc
     8161 tcttcacaat atgagcgaag ataggcagct tcttctgctg attcttctct taattggtga
     8221 ttgatgtgga cgatacctaa agaaaaaccg atttggcgtt gcacttgtaa aagtaaatgg
     8281 agcaaaacca tcgaatcaac accacctgat accgctgcta aaattctcga tccttgttgc
     8341 cagaatcctt gttcattccc gtgccgaata aatgactgct gtaatagcgg tgcttttttc
     8401 ccgccttttt caacgttcat cctttccaca ccctttcttc ctaaaaaaaa gagagcggga
     8461 aaacgtctaa aacgacaatt aacctgccct ctgttgatac tatgacccaa atagtcgcac
     8521 tatcattatt tgcggctttt tagctgcgac gtccgccacg gccaccgcgc tttccttctg
     8581 tgtttcgctt caatgaagat aagcggtcat cgctatcttt caaaaatgaa ctcatcaatg
     8641 aatcgaagtc ttctttttga gctgaaggtt gactgcgaga aaaagatttt ttctgtgctg
     8701 gacgatttcg gttgtcacgg ggatcttttt gttgatattt tttaggacgg ctttcttctc
     8761 cagattcagc aggttgttcc tgcgctttcc ggatagatag tccgattttt ccatcatcat
     8821 ttactgaaat aactttaact gttacttcat ctcctacact taaaacatca tggatgtctt
     8881 ttacatagcc atttgacact tcgctaatat gaactagacc cgtttttcca gcacctagat
     8941 caataaacgc accaaaattt gtgattcctg atacttttcc ttgcagtttt gctcctacct
     9001 cgattgacat aaaaaaaatg ttcctcctaa ttatttccct tttttatatt cctgcttatt
     9061 ttgcagttgt agaactagtt gattgatctg tttcatttgt cgagctgtct gtatttgatt
     9121 ctaatatagg ataaactttt tcaccgtctt ttgagtaaaa gaatttgctt ctggcaagtt
     9181 tagctacata ctcatcatct ttcagcaatg aaacatcttg gtgcagctga tcaacgtctg
     9241 cgttgacttc tttcatttca gtatttgctt cgactctcaa ttcgttcaat tgatgcatcc
     9301 tttgcatgtc atggaaaatc tgcacaccta ttatcgcgaa aatgaccaaa gcaccaacaa
     9361 aaattgcagc cagtctgcgt cttcgaaaaa tcagttgacg ttgttgttgc tgaaattcag
     9421 catacttttt ctttgcatat tccgtatcta gcgcagcgat tttattgctt tttttcgtca
     9481 cttggattcg ctccaatctt tttgattgtc tttttcatta taccaatatc gtgaaagctt
     9541 gtctaatcta tttctctagt gtttctgtgc gattttcaga aataatttcg tacatttttt
     9601 gtgcatcttc ttttttggtt gattcatgta attccgtaat tttcacttcc aacgttttgt
     9661 tgccaaactg gactttcaaa atatcgccta ctttgacatc actggaagat ttcgccaatt
     9721 taccgttgat ttgaattctt cctttatcag ctacttcttt tgctactgat cgtcttttga
     9781 tgattcggga aatttttaaa aatttatcta atcgcatatc ttattcctca ctttttaatt
     9841 tttttattta atcgcaggat tttcttacca aaaggcaaca ttagccattc tcgtactgta
     9901 aacagacgaa gacgaatcac tgcataaatg aacacagaag ccccgatccc aactcctatc
     9961 acgctgacaa aaaaagcagt ggaacgatga gttacaggac caaatactat attcaataca
    10021 ccataataca gcagcagtac tactgtcata caaagaaggc tgaacatcaa cttccgtcca
    10081 aaatgccgtt ctttccaaaa agcatttagc tcttttgttt caattcgaac aaaataccaa
    10141 agcgtcacac ctaatcctaa aagggtagac aggcttgcac ctgctgttcc taataaaccg
    10201 gtcagaaaag aagtagtcaa tccttttacc aatagtcccc atcctgcgcc ttttaaagaa
    10261 gggcgaaacg agttcttgct ttgagcaata ctttgataag cttggatgac tgcagtgaaa
    10321 gcaatggaaa aaacaaataa tacaagcgct gcatttcccg cataatcttt aaacaacgca
    10381 taattgatat aagggagcag caaggctaat cccaaagacg cagctaatgc taaagcggtc
    10441 gtcaatctaa gatagatttt ggctgtctgt aaaaactgac gatagatccg gttggtcaaa
    10501 tgacgagtca acgcaggcag gaatgtcgca cttaatgcag tggcaatcac taaacctaat
    10561 tgtactaaag gctgacctcg atcatagacc ccttttgcta tcttcgcacc gtattctgac
    10621 agtccgtaaa cttccaaagc attttttaca aagaaagagt cgatcagctg gaaaaagata
    10681 agcaatccac tataaatcga aaccagtccg ccttctacca gaaaacgccg gatcaagggc
    10741 tttgacggct gtttgaacaa tggaaaccgt cggaagctta acgctcctcc atgaatcttt
    10801 tgttcatagt agtgaaggat cccatatgcg cataaaccgc caaaaacagc tccactcatt
    10861 gctgccgtcc ctgtttggta caccgtccat ccaagctttc taaaagcaaa cgcactacag
    10921 acaatcacaa aaacacgaac gaactgctca actacttgag aaacagcagt tggttccatc
    10981 aagaatcttc cttggaaatt ccctcgataa aaagatagac caggcatcag caaaaaggta
    11041 aaggaaacta cttggatcag cggtttcaat tgtatgtctc ccatcatcca agcaatccag
    11101 ctgctaaatg caaagacaaa caaccacaaa aagacacctg tccaaaatac taagggataa
    11161 agattttgca aagcttgctt tcgctcgaaa ggattctttc tttctgcaac gtactttgat
    11221 atgaactgcg gaagaccgga taaagctaaa gtcattgcta tcccataaat tggataaact
    11281 tgctgataaa cataaaaacc ttcgtcgccg actaagtttt ggaggggaat tcggtaaagg
    11341 gcacttaata cttttgctat gaaagaagca atcgtcaata caaatgctcc ttgcatgacg
    11401 cgccgcattt ctttatgatc caaatcattg ctccttccta cgctgacaga tatttttgct
    11461 cacgcaacgc tttgacaaac ttttggattt cctgaagcca tactgcttct tccatttggt
    11521 tggggatcgt caagcgtatc accatctgtt ctttttcaac gcctagactg gcttttagtt
    11581 ttgtcgctgt cagtgcttcg aataactgtt ccacactata gcgttttgtt ccaactttac
    11641 ttagagtaaa gactatatgc gcctcctgtt tccttatcgt ttctaggagc gctcgatcgc
    11701 catccatttt gatctgccca attgtcaaga gatgtgctac ttcttctgga tattctccaa
    11761 aacggtcgag cagatcatct tctagttcat ctagcatttc ttgcgaatca agttcacgaa
    11821 ttcgtttata gatctcgatt ttctgccgtt gatctgccac gtatgtttca ggtagatacg
    11881 catcgacacc gaggtcgatc tcaacagtgg tcttctccac ttgactattc tttccttgtt
    11941 tacgagaaac agcttcgctt agcatttgag aatacatatc gaaaccgact gcatcaataa
    12001 atccatgctg ctgagcacct aagagattac ctgcaccgcg aatggaaaga tcccgcatcg
    12061 caatcttgaa tccagatccc agttctgtaa aatctttgat tgcctgaaga cgtttttcac
    12121 tgacttcgtt aaggatcttc tgctgctcat acataaagta agcatatgcg acacggctgc
    12181 ttcttcctac ccgccctcgc aattggtata acgtggataa tcccatataa tcagcgttct
    12241 caacgaacaa cgtatttgcg ttcgggatat ctactcctgt ttcaatgatg gttgtagtga
    12301 caagaacatc atattgacct tcaataaatt caaaaagcgt attttctaat tgcgcctctg
    12361 tcatttgccc atgagcataa ccgatccgtg cttccggaac gagttcttgg atttcttcta
    12421 ctttttgttc gatcgtttct acccgattat ataaatagaa tacttgtcca cctcgtccca
    12481 tttctcgatg gattgcttcg cgaatagccc caggattttt ttccataaca tacgtttgga
    12541 tcggataacg attcgcaggc ggtgtttcga ttactgaaag atcccgcacg cctaacatcg
    12601 acatatgcaa agttctcgga atcggtgttg cagtcagagt caaaacatcc acttgtgcac
    12661 gtaactgttt caatcgttcc ttatgtttta caccaaaacg ttgttcttcg tcaatgatca
    12721 gtagacccaa atcgctaaat tcaatatctt ttgacaaaat tcggtgggtt cctacaacaa
    12781 tatcaacttg acctgtacgc agttgttcga tggtttcttt ttgttgcttt cttgttctga
    12841 aacgacttaa tagcccgata tttacgggga aaccttcaaa tctttccagc atcgtttcat
    12901 agtgctgctg tgccaagatc gttgttggaa ctaaaaaggc tacttgtttg ctttccttta
    12961 tcgctttaaa ggccgctcga agcgctactt ctgttttccc ataaccaaca tcacctacga
    13021 gtagtcgatc cattggtttt tctttttcca tatcccgttt gatctccgct gcacttctca
    13081 actggtcatc agtttcagag taggggaagg cattttcgaa ttctttttgg taggcgtcat
    13141 caggtccaaa agcatatcct ttttctgact ctcttgcggc atataatttg attagatcgt
    13201 cagcgatatc ctcgattttt gaagagactt ttcgcttggt tttcgtccat tcacttccgc
    13261 ctagcttatt gatgcgaggc gctttggctt cagaggcgac atatttttgg atcagattca
    13321 gttgagtaac aggaataaac agtttgtcgt cgttttgata caaaatagtc atatagtctt
    13381 ggtgaacgcc atctacttct agcgtttcca tcccaatgta tttcccgata ccatgattgg
    13441 catggacaac gtaatctcct gcttttaact cattatagct tttcaatcgc tctgcgtttg
    13501 ttactgtttg acgtctcgtt tgttttttcg tcgttttttg gaaaatttct ttttctgtga
    13561 tagctactat tttttcttga ggaagttcaa aaccagcctg caaagctcct tcaactaatt
    13621 gtacctgtcc tctgatcaat gcattttttt ctgtttctac tactaatatg tcttcatctc
    13681 gaagcatttg ttctgctttg cgtattctgt cctttgtcgg aataaagatc acaacagtct
    13741 gtttttgctt gcgccaacgg tccatttctg ttttcagcaa tggcatttgt ccgaagaact
    13801 gttgcatcgt ccgatattga aaattatgga ttgcttggaa acgaagattt cccatccctt
    13861 tttggaagag tgagaaaaag gttgtggtga acttttcctt ctgcacgatt ttttgtatat
    13921 ctgctgaaaa tgtctgctca gaaaacaccc gcaattcgct gattttttga gtctgccatt
    13981 ctgccgcttc cctttcgatt tcccgatttg tttccatgat tcgctgataa tcatcaacga
    14041 ctagtaaact atttgaaggg aaataatcca agatcgtcac agattcttgg taaagaagat
    14101 ctgagtagaa ttttgcttct tctgtcggga cacctgcttg ccagcttgaa gtcagctgac
    14161 cgaagtaatc ttgcaaaaac tcgcggtctg cttcttctgt ggtcgcagca agccgttttt
    14221 ctagcatttt ttgcatttgc tctattccat gttctagatc ctctggtccg tagacttgtt
    14281 cactcgttgg ggaaacccag atttcttccg ttttttcgat tgagcgttgt gtttctgctt
    14341 caaaataccg catagaatct atctctacat caaatagttc tacacgaaca ggataggttg
    14401 tcgttaacgg gtaaatatcg ataatgcttc ctcgaatact gaattctccc ggttttgcga
    14461 ccatctcttc tcgtacatag cccatcaaag tcaattggcg aggaagattt tccacgtcta
    14521 tctcatcacc aatatgccaa ttcaattgcg cctgtagcca agttttctta ttcggcagtc
    14581 gtttgtgcaa agatgcgact ggcaacaaat agatacctgc ttttttttct tgaagtgcgt
    14641 taagcgttgc aactctctcg cctcgcgctt ctggagaaga aaaggccatt tcagcagaaa
    14701 gcacttcatc cactggaaat aaatggatct gatcttgcgg aatcacatgt tgcagatctt
    14761 ctgctaactg attcgcataa tacaaatttg gcatcagaat aatcatgttt ttatttgttt
    14821 tcttaaacgc tcgagcaaat agaagtgttt tcgctgagcc cgctaatcct gtgattagtt
    14881 gtctaggcat tttttcttct aaattgctga cccattcttt tacttgcgga tcttttccga
    14941 ctaattgaat aatatccatt ccttttcctc cttcctcaat tgaatcgatt catcgcatcc
    15001 acgaacgaat gcccttctat gagatattcg actgctttaa cagattgaca catgctttct
    15061 tctatcaaag gctgattttc tttgctgaaa ggactaagca catgctggac tactgttttt
    15121 ttcccttctg gcctgccgat tcccaccttg attcgatcaa agacattcgt attcaaatgg
    15181 gaaataatac ttttgatacc gttatgcccg ccggcacttc ccttttgacg gagccggatt
    15241 tttcccactg ccagatccaa atcatcgtag attacgacta attcctctgg ataaatccca
    15301 aaataagtca ttagtgggcc gactgcacga ccagattcat tcatgaatgt ttgtggtttg
    15361 actaaaagga tcttttctcc attatgaaaa aattcggcaa cttctgcttc gaacggattt
    15421 tttttgaaag tagcttgatg ctcgcgtgca attttatcca cgaccataaa gccgatattg
    15481 tgttttgtat attggtattt ggtacctggg tttcctaacc cgacgatcat tttcattttt
    15541 gttttccacc taattctaaa aagcagcaca aaaggctgga ctgctaatta gcggtccagt
    15601 ccatcgagct tttttctttt ttacacttgt caatgcatag tataacacaa aacaaggcgt
    15661 ttcggctaaa agagaatcgt taataaatga taaagaaatt aaaaatttct tcaaagttta
    15721 atgaaataat tgatatataa aaatagtgaa ataacgcaca tgtaagcttt tacatataat
    15781 acaaccttgt tatctgttat attttatagc caaatagcgt gacatggggc ttgagaaatg
    15841 ttagcataag catgggaaaa aacaaatcaa tggaaggatt gatactaaat gactgcagct
    15901 gcagaaaaaa aagatcatca aaaagttatt cttgttggag acggcgccgt aggttctagc
    15961 tatgcctttg ctctagttac tcaaaatatc gctcaagaag taggtattgt ggatatcaat
    16021 actgctaaaa ctgaaggaga cgcaattgac ttgtctcacg ctttggcatt tacttcacct
    16081 aaaaaaatct attctgctac ttacgcagac gcacatgatg ctgacttagt tgttattaca
    16141 gctggcgcac cacaaaaacc aggtgaaact cgtttagact tagtaaacaa aaacctaaaa
    16201 atcaaccgcg atgttgtcac acaaatcgtt gaatcaggat ttaacggtat ctttttagtt
    16261 gccgctaacc cagtagatat tttgacttac tcaacttgga aattctcagg tttccctaaa
    16321 gaacgcgtaa tcggttcagg tacctctctt gactcagctc gtttccgtca agcacttgcg
    16381 gaattagttg acgttgatgc acgtaacgtc catgcttaca tcttaggtga acacggagat
    16441 tcagaattcc cagtttggtc acatgcaaat gttgccggct tgcaaatcta tgaatgggta
    16501 aaaaacaacc cagaaatcga tgaagaagct atggttaacc tattctttgg cgtacgtgac
    16561 gctgcttaca caattatcga gaaaaaaggc gctactttct atggtatcgc agtagcatta
    16621 gcacgtatca ctcgtgccat cttagatgat gaaaatgctg ttcttccttt atcagtattc
    16681 atgaatggcg aatatggatt gaacgacatc tacattggtg cacctgctgt tatcaaccgt
    16741 caaggtatcc aaaaagtaat cgaaattcct ttaagtgaca gcgagcaaga ccgtatggct
    16801 gcttctgcta agcaattaaa agaaattcta gatgaagctt ttgctaaact agacgctgaa
    16861 taatctttga acatgacgga aaacatctat tcggtgtttt ccgttttttt attttatcac
    16921 ccttatggtt tctaaatttt ttcataaagt agagataacc ttcgtctttt cctctaaatt
    16981 atgctatcat gagaccgttc caccctaaac ttttacttaa ggagttgtcg atatgacaag
    17041 atcttcgcat cgaaaaaaat cgaaacatgt tgctttgctt tcagttcttg gtgttctctt
    17101 agtgctgatc agcttttata cctatcgcag tacatactac acaaagcatt ttttgccgaa
    17161 tacagaaata aatggaataa atgtcagcaa tctaacagtc gaaaaagcaa atgaaaaatt
    17221 aaaagaagct tattctgata aaaaactggc tattaaagaa gatggaaaag tctggcagga
    17281 agtaccaaaa tccgagctcg gctacaaaga tgatttcact tcggagcttt ctccgatcct
    17341 aaatgaacaa aacggatgga cttggggaat gacttatgtc tcagcggcag aaaaacaaga
    17401 aatagatcct gtcagtcaaa accaccaaaa actagacact accgttcaga cattgacaac
    17461 taagctgact gatttgaaca aagaccggac acctactact gatgcaacga tcgaaaaagc
    17521 aggtgactct ttcgttatca agcctgaagt caatggaaat acgatcgacg tcgatgctgc
    17581 ggtcaaacaa ttaaaaagtg cggtaaactc tggtaaagat acaattgaat tgactgaatt
    17641 caaagaaaaa ccaaaagtaa catctgaaga cagctcactg aaagaacaac tcgcatccat
    17701 gaatgctatc gcaaatgtaa aagctactta cagtataaac ggtgagactt tccagatccc
    17761 atcaagtgat attatgagtt ggctgaccta caatgatgga aaagtcgatt tagatacaga
    17821 acaagtacgt caatatgtaa cagatttagg cacaaagtat aacacaagta cgaatgacac
    17881 aaaatttaaa agtacaaaaa gaggagaagt tacggtccca gttggcactt acagttggac
    17941 gatccaaaca gacagtgaga cagaagcatt gaaaaaagcg attctggcag gccaagattt
    18001 tactcgttca cccattgtgc aaggtggcac aaccgctgat catccattga tcgaagatac
    18061 gtatatcgaa gttgatctgg agaaccagca tatgtggtat tacaaagacg gaaaagtggc
    18121 ccttgaaaca gatatcgttt ccggaaagcc aactacacct acacctgctg gagtcttcta
    18181 tgtttggaat aaagaagaag atgcaacttt aaaaggaaca aatgacgatg gaacacctta
    18241 cgagagtccg gtaaactact ggatgccgat tgactggaca ggtgttggta tccacgattc
    18301 agactggcaa cctgaatacg gtggagactt atggaaaacc cgcggttcac acggctgcat
    18361 caacacccca ccaagtgtaa tgaaggaatt attcgggatg gtcgaaaaag gaacgcctgt
    18421 attggtcttc taacaaaaat aatatataaa aagaaagcac ccgtacgatt ggtacaggtg
    18481 ctttcttttt attatctaac aatgtgctac ttacatttca gcagcagtaa agacttctga
    18541 aacatcatca tcgtcttcta gcttatctac tagacgttcc aattgctctt tttgttcctc
    18601 atttaaatca atcgtcgttt gtggaatcat cgtcaattct gcttgcgcca aagtgaactc
    18661 tttttccaac tcatctcgta cagcagcaaa atcttctggt gcagtataaa tctcgaatac
    18721 ttcaggagaa gtttgcagat cttctgcccc cgcctctaat acatcctcaa acatcgtctc
    18781 ttcatcaaca gtcaacccat cgcgttcaat agcgatatat cctttgcggt caaacaagta
    18841 actgactgaa cccgtttctc ccagtgatcc accgtttcga gtaaaagcta ctcggacatt
    18901 tgtcgctgtc cgattacggt tatctgtcaa tgcatggact aagattccta ctccacccgg
    18961 accatatcct tcatacgtga tttcatcgta attcgtttca tctacggcac tcgtagcctt
    19021 tttaatcgcc cgttccacat tgtcgttagg catatttgca gcttttgctt tgtccacaac
    19081 aagccgcaaa gctggattca tagatggatc aggaccgcct gctttagctg ccatataaat
    19141 ttcacgagaa agtttctgaa agactttccc tcgttttgca tcttgggcat tttttcttcc
    19201 ttggatatta tgccatttac tatgtcctga catgattttt cctcccttgt tcttttgaga
    19261 atacacttct attctagtac tatttcacaa aaaaacaaag ccacagccaa tctataaacg
    19321 cttcttgaat gccgcaaaaa gcacacataa tatcacagca gtcagagcac cgatcgaatc
    19381 caacatgaca tcttggaaca taggtgttcg tccaccggtc atcatctgat ggaattcgtc
    19441 caaacctgcg taccctgttg ctgaaagcca agcaaggatc gctgtcagcc accaaatttt
    19501 tagcttgggg aaaacaccta aaaacaagct gcctcccaaa ataaaatagg taccgaaatg
    19561 tgcgcccttc cttaaaaaga actctaaaaa tttggcgtag cccagatggt tgatactcac
    19621 catacttcca ccataattaa aacgtatacc cgctaatgtg tctttaaatg gctgattagg
    19681 cagccagctt tctaatcgcg aaacttgtga ttgctgtccg taagtttgag aagaactgta
    19741 aaataagatt ataacgacta tcagtgcgat tactaaataa atatttccgt ttttcatttg
    19801 tttttttgaa gaattcataa gtcacctctg tattttatct tagacttttt ttgaagaaac
    19861 aacaatcatt ttcatagaga cttcttccat aaaaaagtgc tatacttaat tttgtattac
    19921 aatatgaagg gagttttttc atgagttatt cattaaattg gaatctagat tctatttttt
    19981 ccggaggcag tcattctgat gctttgaacc aacggatgaa gcaattggaa gaccaaatga
    20041 acgagtatta tcaccgcgta acaaaatggt cacctagttc tgacaatgca gagcagttaa
    20101 acgctattct tcaattgcaa gaaacgatta cgaatggttt tacccaatgc agcagctata
    20161 ttactgcatt gctttctgcc aatgtcaatg attcagatgc aaaggtctta tcaggcaagc
    20221 tttacgcaat gctgcctcgt ctgcaatcag ccgaaactgt attgtcaaag aaatttgcag
    20281 aaatatctga caatgattgg aatcagatgc tttctcaatc ttcgtttgaa acaattgctt
    20341 ttcgtttaaa cgagattcgt cgtgatggct cacaattatt atcagaagct gaagaaaaca
    20401 ttataaatac gctttcttta gatggtctaa atgcttggag cagtcattat gatacgattg
    20461 tagccagcat ttcgattccc ttcgaacaag atggacaagt agtcgaatta tctgctggac
    20521 aagccttcaa taagatgatg ggcgatccag atccaaaagt cagagaaaca cttttcgcag
    20581 catgggaaga agcctggaaa gaaaaggcac ccctcttcac ggatactttg aatcatttag
    20641 atggttttag actttctgac tatgaacttc atggtgtcac agattttcta caaaaaccat
    20701 tagagtacaa tcggttgaag aaagaaacat tgtctgtcat gtgggataca atccagaaaa
    20761 acaaacaacc ccttgttaat tacttgacta gaaaagctaa tcttttcggt aaagaaaaaa
    20821 tggaatggca agatcaagat gcacctatta ttttaggcga tttgaaagaa aaaaccttta
    20881 gttttgacga agcagcagca tttattatcg aaaactttaa caaattcagt ccaaaaatgg
    20941 ctaaatttgc ccaatctgct tttgaaaaga gctggatcga agcagaagat cgtcctggga
    21001 aacgtcctgg tggttattgt actgagttac cagaaacaaa agaatcaagg atctttatga
    21061 cctacagtaa ttctgttaat gaggttgcga cacttgctca tgaactagga catgctttcc
    21121 atagcagcac gatgtgggat ttaccttctt taaatcgcga atatgccatg aatgtcgcag
    21181 aaacagcaag tacattcgca gaactgatcg tagccgatgc tacattaaaa gtcgcaaaaa
    21241 caaaagaaga aaaaatcaat ttgctagata caaaactgca aaatgcttta gctatgttca
    21301 tgaatatcca ttcccgattc atttttgaaa atcgattcta tgaagcacgg caagaaggat
    21361 tagtctcaga agataagatc acagagatga tggttgaggc gcaaaaagaa ggctatcaag
    21421 gagctttagc tacttaccat ccatatttct gggctgcaaa attgcatttc tttattgatg
    21481 acgtaccgtt ttataacttc ccatacacat ttggctacct ctttagtttg ggcatctatg
    21541 cttacgccaa ccaaaaggga gcaaattttg aagaagaata tatccattta ctacgcgata
    21601 ctgcctcaat gacgacggaa gatcttgcga agaaacattt gaatgtcgat cttacccaac
    21661 cagatttttg gcaagcaggt atcgacatgg tgactgaaga tatccaaacg ttcatggaat
    21721 tgacagaaga atttatctga tttctatttt atcacaataa aaaaagagtt agtccagaat
    21781 gggctaactc tttttgatta atcattctta catgctgaca gcaaagtcag gggcaaacca
    21841 ttgaactgaa ccaactttta cgctttcgcc tggttgagga gcatggatat attgtcctcc
    21901 gcctaaagca atcgctacgt ggtaagttcc gccttgtgac ccccagaata acaagtctcc
    21961 agcttttgct tgagaaactg aaatttttgt tccagctgat tcttgaggaa ctgtccaacc
    22021 accgatgtca cgaccagtta cttgcatgta aacatagcgt gtgaaccctg agcagtcaaa
    22081 gccacttgga tctttaccgc cccaaacata tggagtacca atatatttgt aagcttctgc
    22141 tacgattgct gcaccattca cacttccaga aggagctgga gcaggtgtta caggttttgg
    22201 ttgttcaggt gttggtgttg gcgttggagc cggagtacta cttcctgtgc cgtttcctgt
    22261 atcaacactt tgatctgttg atggtgttgt aggcgcaggt gttgttgatt cttctgttgt
    22321 tgaagattca ggcactgttg ttgattcttc tgttgctgaa gattcaggca ctgttgttga
    22381 ttcttctgtt gctgaagatt caggcgctgt tgttgattct tctgttgctg aagattcagg
    22441 cgctgttgat tcttctgttg aagattcagg tgttgttgat tcttctgttg ctgaagattg
    22501 tgtagctgat gatgattctt cagtcattga agattgtgta gctgatgatt cttctgttgc
    22561 tgagctttgt gcagtagatg aagcttgagt agcttgtgct tcagcctctg cttgttcgcg
    22621 tgcttctttt tcagcttttt cttgtgcagc ttgttgacga gcttgttctg ctagacgttg
    22681 ttgttcacga atacgagctt gctctgcttc agcttctgct ttttgacggt tcaagtcagc
    22741 tttcttgtct tcagcagttg cttgttcagc agctaatgaa gttttcagta cgttcaaatc
    22801 agcttgttta gataaaagat cgcctttttg agattccaaa gcagcttggt tttcagctaa
    22861 ttcttttagt ttagcatcgt tttcagcttt tttgtcttct acagcttttt tatcttgttt
    22921 ttgttgttcc atcaagtcgt tgtttgcttt taccatcgtt gtcattgctt gaacgcgtcc
    22981 aatagcatct gctaatgaat cagcattcaa tacagcatcg atgtagtttg agcttgtgtt
    23041 gcttacttgt gcttcgcgtg cttgtttttg gattgtatct tcacgttttt caatacgttc
    23101 ttgtaaatct gcaatgtctt ttactaattg tgcagattct tgacgcaatg tatcttgttt
    23161 tgctaatagg tcttgtgctt gtgtgttgat ttcagaaact tggctttcta aggcatcgat
    23221 ttgtgattgt gcatctgctt gttgattttt caagtctgca atcttttgat cttgctgttg
    23281 tatctgagaa tcaaaatcgt ccgccgcggc agcgatcggt gatgctacgg cagtcaaggt
    23341 cattgaacat accattactg ctgatattaa actctttttc actcttcatt cctccgactg
    23401 gcttaattta ataaatatct aaatatattt aagtctttct taacgatata aaaattgtac
    23461 catagcagtg tgtcaacgat ataatagtta tgttacaaaa atgtttcaaa acaactttta
    23521 aaaatgacaa aactgttcgt ttcagaaaat gatcatgaaa aagccgcgtt aagtctagca
    23581 tttcttaaga taacaacgat tctttttcgc tttcgaccta aaaataaaaa aagaaattat
    23641 tcatcactga ataatttctt aaagggaaaa atgaataata caaatataat catgttcaac
    23701 agcagtgtag gtcctaaaaa ccttgtaata aaatacgtgt tatttactac tgctaattta
    23761 aaaatcaact ggaccaccat cgtaaacaat tcataacccg tgacaaagat gatcatactg
    23821 aaaaattcag taaagatgtt gacatggata acgtctttca ttacatacat caaccataca
    23881 attaaaggga gagctactgc atagataccg ataacgccaa tatagtaagc gtcatagata
    23941 gccccgagaa caatcgtggt aatcagtaaa taacgttttt caaacgccat actgcaacat
    24001 aataatgcca atatcagaaa gtgggcattt gacatatagg tgcctttcga ccactcccct
    24061 agcattcttg ttaaatgacc atctatcaac atcaaaaaga acaaaacgat tggcagatag
    24121 tacttcattg tttctttctt caacatggac taatcctccg ctagccgttg gacaatcgtc
    24181 acaactgaca cgtcatacat ttctgcataa ggtttcacat aaacttcccg atccagccca
    24241 taactatctg gtttcgtttt aataaccgta ccgatcggca agttagctgg agaattccct
    24301 ccaagaccgg atgtctggac aacatcccct tctttgatat ccgtatcacc agttaattgg
    24361 gtcaccacta aggcatggag cttttcatca tagtttttaa gcaaaccaaa cgcttcgcca
    24421 ttagccgaag atacccgtac tggaaaatga ttggagcttt cattagagga tgacagtaat
    24481 tcgattttag acgaagccgt attgacctcg atcactcggc caatcaatcc tttttgcgac
    24541 atgactgcca tatttgcttc gataccgtct ttagaaccct tgtctacgat cagcatgtcc
    24601 tgccaactgt caggcgaacg agtaatgaca tttgccgtta ctttttcgta actagtcagc
    24661 gtctgattca actcaagttc ttttttcaac gcttcgattt ctctctcgta attcttgttt
    24721 tgctgtgaaa cgtcatcata gctatcgatt ttttctttta gccgctcatt ttcggcataa
    24781 gttgaaaaaa gattatggac agaatctact ccatttcgta cccaccgtac tggggcagag
    24841 attgttttat caaccattgc aacactgtca ttaacgatgg attggaagaa attgggcttt
    24901 ccttcattcg ctcgctgcgc agcggtcaca cttagtatcg tcaccacgat gataacaata
    24961 accaaggtaa taataatatt tttattagga ttgaacttct tcacaaagac acctcgaatt
    25021 aattagactc ttgtgttcaa ttttatcact aaatgccgtg aaacaaaagg taagttgctc
    25081 ctcttaagct tttttttagc aaataataga ttctgtcatt tttagcctga aagacaaatt
    25141 tttttatttg tttatggatc aatctttgct ttgaataact gcaatcatac catctgaaaa
    25201 agaaaattct gcggtatctg aaagaaattc gttacttgca taagatgtcg gatattctac
    25261 ttctttattt tccaatacat acttgctgcc ttttaatgta agattcgaga cgggagtcaa
    25321 gcagcaataa gctaaatact tcatatctgg tatctgtctt actatatgct ctccaggcaa
    25381 ataataagac aaataatttt gacaatctct gataataagc tgatgggcaa agggtttgaa
    25441 gcgaggttcc atacctaacc agagattggc taaaagatga tccaatcttc cgcccgtagc
    25501 tccaatcaaa gtgacttccg cttgcgggta acgttcaaat gtttttaaga tacctaactg
    25561 tgtatctgta tcgtcttttt ctgcagggga acgggtatac tctttggctt ttgcaaatac
    25621 ttccttctgc tcttcgttcg acaatgaatc aaaatcaccc actgccagat ctactgggta
    25681 gcctgcttga agcaggtaca gcgcaccacg gtctatcccg acataggcat cgtatttgga
    25741 cagcagagac tgcggccagt tttgcggatt acctccagca gctaataaaa ttttcattta
    25801 gtctaatgcc tcttttaatc gttcgatttg tccgactgga ttttcggctc catagatata
    25861 tgatcctgca acgaagacat ccgcccctgc atctttacag atttttgctg tttctggaac
    25921 gattccgcca tctacttcga ttgcataagt ccaattgttc tctctacgta gatcagcgag
    25981 ttccgtaatt ttttctactg tttcttcaat aaagctttgt ccgccgaacc caggattgac
    26041 agtcatgact agtacttgat cagccaaagg caaaacatgt ttgatcatgg agactggtgt
    26101 tcctggattg ataactactc cagctttaac tcctaagctt tttgtcattt gaagtgcccg
    26161 atgaatatga ggagttgctt cgacgtggac agtaatgata tctgctccag cttttgcaaa
    26221 tgctggaatg tagttttctg gatcaacgat catcagatgg acgtctaacg gtaatttagt
    26281 aacaggacgg attgcctgaa caatatttgg ccctaatgtg atatttggga caaatcggcc
    26341 atccattaca tctacgtgga tgtaatctgc gcctcctttt tccactaact caatgtctct
    26401 ttgtaaattg gcaaaatctg cactcaaaat ggatggtgct atcttcattc ttgtttcctc
    26461 ctattttcgt ttaccttctt tttttgcata cattggtttt cttttttcga tttcttgtaa
    26521 gaattgcaaa taattgtcgt aacgtgtctg tgcgatacca cctgtttcta ctctatgttt
    26581 tacttcgcag ccaggttctt tagcatgcat gcactctcta aatttgcaat ggacagaagc
    26641 ttctacaaat tcaggaaatt gtctcggcag ttctcctgct tcaattgtca aaaagtcaat
    26701 cgagctaaat cctggtgtat ctgctactaa cccgccatag ataggaatca gttccacatg
    26761 acgtgttgta tgccgtcctc ttccaagtgc atcagaaatc tctcctgttg ctaaattcag
    26821 ttccggtgat atttgattca gtagcgtcga ttttcctgct ccagactgac ccataaagac
    26881 cgatagccgt tctgggaagt aacggatcag ttctgtcgta tcacccgtat gattgggtac
    26941 aatcaccgga tagcctattt tagtataggt ttgcttgatc tcttcgattt tttctgggtc
    27001 gtctgacaag tcggtctttg tcaaaaaaat aatcggttcg atcgactcgt attccaaggt
    27061 aactagaaag cggtcaagta gattataaga aaatgcaggc tctacgatac ttgtgacaat
    27121 gattccaaga tcaacatttg tgactggtgg gcgaactaat tgattttttc tcggcaagat
    27181 ttccagaaga tagccgtctg tttgattttc actctcaaag atcacctgat ctccgacaag
    27241 cggcgtgatt ttccgattcc ggaaatttcc tcttcctctt gtttgatagg tctctccgtt
    27301 tgcgtataca tagtaaaaac cgctgattgc ttttctgatt tgtcctttga taagtgccac
    27361 ctccgttttt gtttatttta ccatacgaag aggaaagtag gtgttattcc atgcaaactt
    27421 ctcaaagtat atggcttgaa aattgatcaa aagagataga aacacaaaaa agagaatgca
    27481 acaaatcaat gtcgcattcc cttctgatat attttattca gcacttattt tgaactttct
    27541 gaggtgctag ctgatgaact tgtggagctg gaagattctt cttttgaaga gttgcttgtg
    27601 ctactggagc tacttgagct gctagaactg tctgaagagt ctttttcaga actagaagac
    27661 gctggatctg gtcctttaga gtaaattacg ttcacaacca ttcctttggt aattgtcgtt
    27721 cctgcccctg gtactgtacg aatcacttta tctttatcca ccgtgtttga atattcggaa
    27781 gtctcatgcc cgatatattc tgcaccgaca ctagctaaat aactttgtgc ttcgcttttt
    27841 gtatagccgg agatatcatt caatttaggc tctgttcctt ggcttacgac aaaattgatg
    27901 taagtttctt ctgctacaac ttcacccgag gctggatcct gactgatgat cgaacctgat
    27961 ggtacagtgt cgctatagtc ataagtagca ctaatattat tgatattgaa tccttgtgta
    28021 acaagccaat tacgaacagt ttcgtagttt tctcctacat gactactcaa agtcactgtt
    28081 tctggtcctt tgctgactgt gaaagtaatc gtgtctgttt taggatcgac ttctgtatct
    28141 tctgatggag attgcgaaat gatcattccg ctttctacct ctgaactgaa ttcctcttct
    28201 ttttgaatca agtcagcaga aaaccctaat tctttcaaac ttgcttcggc atcttcataa
    28261 cttttaccac tgtaatcatc taatttgatt tttttcgtgc cgctactaat atacagagtg
    28321 acttcgcgtt tttgcttgac tgtcgttccc gctgccgggt ctgtcttcac tacattacct
    28381 tcttcgattt tgtcatctgc aatttcttct gtttttgttg ctacttctaa tttcgctttt
    28441 gcgagtgttt ctctagcaga agcttcagaa agatcagaaa catcaggaac aacaacttct
    28501 cctcgcccgc cagaagcaaa gaatacagct gttccgattc ctaaaacagc aagaatagct
    28561 aataggatca gccaccattt tttctgtcct ttctttttag gatcaggcag aacttcttcc
    28621 tcctctggta aggtttcgtt ttctggcttg tcttttggca gaggcataga tttgaatgaa
    28681 tcaggcattg gtgcatcttc cgtaaggggt gtgataactt ttgtttcatt atccatcaca
    28741 tgaggctgcc atttttcttc gtttgcacga gctggtgata atactgtaga aagatcatca
    28801 gacatttcct cggctgactt ataacggtct gcaggttctt tagccgttgc ccgtaaaatc
    28861 acgttttcca gtgcttgtgg cacatttgga tcaagtgctt ttatagatgg aagatcatct
    28921 tgaaaatgtt ttaaagcaat tgttacagca gattcaccat caaacggtac gctacccgtc
    28981 aacatctcat aaaggatgat ccctaaagca taaatatctg actgcttcgt tgccatactt
    29041 cctctggcct gctcagggga cagataatga acagatccta gcatcgtatt cgtctgcgtg
    29101 atcgatgttt cagataaagc gatagcaatc ccgaaatccg tgatttttac aacaccttca
    29161 ttatcgatca gtacgttttg gggtttcaaa tctcggtgga tgatttgatg gttatgagct
    29221 aaagaaatag cagaaaggat ctgctgcata atatttactg ctgtttcata aggaacagga
    29281 taatgtgttt ggatatatcg tttcaagtcc attcctttga cgtattccat caccagatac
    29341 tgcatgttgt cttcttcacc aacatcgtaa acactaacaa tgtttggatg aacgagttct
    29401 gttgctgcta aagcttctct ctgaaatcgt cgaatcgcag tctggtcatt ttgaaagtca
    29461 aatcgtaaga ctttaactgc tacatcacga tccaagatta aatcgtgcgc caaaaataca
    29521 tttgccatac caccgctacc gatatttcca gtgatttgat aacggccatt taattttttg
    29581 cccaactcga tcatacactg tcctccttat attcgataag aagaacggtg atattatccg
    29641 ctccgcctgc ttcattggca cgatcaatca gctcagttac tttatgagac aatgggcctt
    29701 cttgattgat gatcgttcct atttcttctt cagacagcat gttcgtcaag ccatctgaac
    29761 ataacagcag tcgatctttt agttgccaaa gatgagtaga aacatctact tcgactgttc
    29821 caggcatgcc gacagaacgt gttaaaatat ttttccttgg atggttcact gccatttctt
    29881 cgctgatttc tcctgatttg actagttcat tgactaaaga atgatcctcc gtcaattgca
    29941 tgattttatc ttcacgaatc aaataagctc tgctatcccc aacattggca atcgtgaacc
    30001 agtcatctga cagagcggcc gctacgattg ttgttcccat accgttatat tccggctgtt
    30061 cttgtccacg ctgataaatc agcatatttt cttcttgaat cgattgaatg aaccattggg
    30121 cgattttttc atcgtcaaca gcttcttgtt tttcccaagc ttcgcctaga ttcgttaccg
    30181 ccatctgact ggcaatgtct ccggcacgat gaccacccat cccgtctgct aatacagcaa
    30241 gcttgagacc tgaacggctg gtaaatacac tggcatagtc ttgatttgtg ttacgtcgtc
    30301 ttcctacatc tgattgatat tcaatctgca ttttttcacc tcattacttt ttgcgcaaac
    30361 aacaaatgaa aaatccatct gtgtaaaact gatgcggata caaagtcaac attttctctt
    30421 cgattgatga ttgtagcata ggattggtca aaacatcaat cctctcaaaa tcagggtgtc
    30481 tttccaagaa agcagaaaca acgtcttggt tttcttcttt taagatcgta caagtgctat
    30541 aagtcagaat accggaagac tttaaagttg gtgcgcagct ttctaaaatt tccaattgga
    30601 tttttggtaa attcgctaat tcatccggct gttttttata acgaatatct ggttttcgcc
    30661 gaagcagccc aagacctgaa caaggcgcgt ctactaaaat ccgatcaaac tgctctgctt
    30721 cgaactgttt actgacttct ctagcatcca tcttttgagc gtagacagca gaagagacac
    30781 ctagacgtgc tgcattatct tcaatgagtt tgactttgtg ttcgtgtaca tctaaagcga
    30841 ccacttctcc accgcatgac ggatctaaaa aagaagcaat atgcgtcgtc ttacctccgg
    30901 gtgctgcaca ggcatctaag acatgatgtt caggctcgat ttgcatagac ggcgctacaa
    30961 gcatcgaact ttcatcttgg atcgtcatga cgccatcgtg gaacaatgag ctagaagcta
    31021 aatgcccttt tttcgctact ataccgtatg gactgacttg gcttttttca gctgtgatct
    31081 cttcttcttg caaaacagtg atggcctgat ctctggaaag tcggcgtgta tctactcggg
    31141 cactagcatg gctaggctga tatagcgata aaccgagctt ttcagtttct tcgtatccga
    31201 tttgatccac cagtcgtttc gtcatccata gaggcaggct gattttgaca gaaagtcttt
    31261 cgataggatc agcaatgcct tgcagatctg gtgctccttg acgctgataa ttcctcaaga
    31321 caccatttac aaatttccct gtcccaggat ttccttttac ttttgcgatt tcgaccgcct
    31381 cgtttaaaat agcatgtgca gggactttat ctaaaaattc taattggtat acagaaagat
    31441 aaagaagcat cttgacccag tcatccactt tttttgcttt agcgatcaat ggtgcaacgt
    31501 aaaattccaa tagtcgctga tggctaatcg taccatagat caattctgta aataaaccca
    31561 catctttttg atttagctcg ctttgtttga tcatctcatt caacaaaaga ttcgagtagg
    31621 cgccaccctt gttcactcgc tctaatgtca gtaatgccat atatcgtact gattttttca
    31681 tttttttagg gatttttttc attatttcac ctgctgacca atctgaactt gctgaccgct
    31741 tccgttaagg aaatcatgta cggcctgttt tcctttacca gctggctgta attcattgat
    31801 ggctaagacg gtctgtttac cgcaagcaat ccatagattt tttttgtctt tccggatgat
    31861 cgtaccaggt gctttgtctg tagtttctgc caatacttca accgataata atttccagcg
    31921 tatgccctca taggtcgtga atgcaattgg ccaaggacgc attccgcgta cttggttgtc
    31981 aatttcttct gcagttttat gccaatcgat tgcttcttgt tcccgtgtga tgtttggcga
    32041 aaaagttgct tctgactcgt cttgaggtac tggtttttgt ccatccaaaa tattgggcaa
    32101 tgtttctagc aatagctttc ttcctaaaag gctaagcttt tcaaacatcg tccctacatc
    32161 atcttgttta gtgattggta tgctttcttg cgcatagatt ccgcctgcat ccattttttt
    32221 gatcatttcc atgatcgtta caccagtttc tttctcccca ttcatgatgg cataatgaac
    32281 aggcgcacct ccccgatatt taggaagtaa agaagcatgg acattgattg cccctaattt
    32341 tggtacttgc aataactttt caggcaagaa ttggccaaat gccgcagtga cgatcacatc
    32401 aggcaccaat tcaatgattt cttccatttc tggcgaaccg gagattttct ctggctgcag
    32461 cacacggata ccgtgcttca gagccgcttt ttttaccggt g
//
LOCUS       DASHXG010000030        31014 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.030, whole genome shotgun sequence.
ACCESSION   DASHXG010000030 DASHXG010000000
VERSION     DASHXG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.030"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(405..2480)
                     /locus_tag="U2R59_001600"
     CDS             complement(405..2480)
                     /locus_tag="U2R59_001600"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEM8965991.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2482..3399)
                     /gene="glyQ"
                     /locus_tag="U2R59_001601"
     CDS             complement(2482..3399)
                     /gene="glyQ"
                     /locus_tag="U2R59_001601"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEM8965992.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3783..4595)
                     /gene="recO"
                     /locus_tag="U2R59_001602"
     CDS             complement(3783..4595)
                     /gene="recO"
                     /locus_tag="U2R59_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEM8965993.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4738..5637)
                     /gene="era"
                     /locus_tag="U2R59_001603"
     CDS             complement(4738..5637)
                     /gene="era"
                     /locus_tag="U2R59_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEM8965994.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5652..6047)
                     /locus_tag="U2R59_001604"
     CDS             complement(5652..6047)
                     /locus_tag="U2R59_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HEM8965995.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6031..6507)
                     /gene="ybeY"
                     /locus_tag="U2R59_001605"
     CDS             complement(6031..6507)
                     /gene="ybeY"
                     /locus_tag="U2R59_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEM8965996.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6524..8716)
                     /locus_tag="U2R59_001606"
     CDS             complement(6524..8716)
                     /locus_tag="U2R59_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HEM8965997.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8740..9711)
                     /locus_tag="U2R59_001607"
     CDS             complement(8740..9711)
                     /locus_tag="U2R59_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEM8965998.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10417..11796
                     /gene="brnQ"
                     /locus_tag="U2R59_001608"
     CDS             10417..11796
                     /gene="brnQ"
                     /locus_tag="U2R59_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEM8965999.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11952..12398)
                     /locus_tag="U2R59_001609"
     CDS             complement(11952..12398)
                     /locus_tag="U2R59_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HEM8966000.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12425..12601)
                     /locus_tag="U2R59_001610"
     CDS             complement(12425..12601)
                     /locus_tag="U2R59_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEM8966001.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12763..13191)
                     /locus_tag="U2R59_001611"
     CDS             complement(12763..13191)
                     /locus_tag="U2R59_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8966002.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13283..14143
                     /locus_tag="U2R59_001612"
     CDS             13283..14143
                     /locus_tag="U2R59_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HEM8966003.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(14227..14577)
                     /locus_tag="U2R59_001613"
     CDS             complement(14227..14577)
                     /locus_tag="U2R59_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEM8966004.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14593..16320)
                     /locus_tag="U2R59_001614"
     CDS             complement(14593..16320)
                     /locus_tag="U2R59_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEM8966005.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16533..17459)
                     /gene="trxB"
                     /locus_tag="U2R59_001615"
     CDS             complement(16533..17459)
                     /gene="trxB"
                     /locus_tag="U2R59_001615"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEM8966006.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17604..19040)
                     /locus_tag="U2R59_001616"
     CDS             complement(17604..19040)
                     /locus_tag="U2R59_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEM8966007.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(19037..20440)
                     /locus_tag="U2R59_001617"
     CDS             complement(19037..20440)
                     /locus_tag="U2R59_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEM8966008.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20670..21572
                     /locus_tag="U2R59_001618"
     CDS             20670..21572
                     /locus_tag="U2R59_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8966009.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21613..23499)
                     /locus_tag="U2R59_001619"
     CDS             complement(21613..23499)
                     /locus_tag="U2R59_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8966010.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23596..24447)
                     /locus_tag="U2R59_001620"
     CDS             complement(23596..24447)
                     /locus_tag="U2R59_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8966011.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24905..26689)
                     /locus_tag="U2R59_001621"
     CDS             complement(24905..26689)
                     /locus_tag="U2R59_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966012.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26689..28440)
                     /locus_tag="U2R59_001622"
     CDS             complement(26689..28440)
                     /locus_tag="U2R59_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8966013.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28582..28806)
                     /locus_tag="U2R59_001623"
     CDS             complement(28582..28806)
                     /locus_tag="U2R59_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEM8966014.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            29057..30643
                     /locus_tag="U2R59_001624"
     CDS             29057..30643
                     /locus_tag="U2R59_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HEM8966015.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         8675 a         6651 c         5522 g        10166 t
ORIGIN      
        1 ttttacactc tctgattgac gtcataaaaa gtagctttga attcataatc gtttatataa
       61 cgattaatag aaaacaatat agtatttagt gttcatacaa tgattctaag atcattttga
      121 attaatcagt cttatagttg atttctaaat tgtcatatat tattaaaaat ttttgccatt
      181 taaaaagaaa agcgacagtt taccaataaa tttcaactga attatctaaa agtagatcag
      241 ttagtttaga taattcagtt gaaattgacc gactcaaatt acttgtataa tacctaggaa
      301 aaaattaact agcaccacgg gtatagttat ttatatttat aacaaataaa ccagagaaat
      361 agcctatttt gtgcctattc tctggtttat ttacatatta gaaattattt tgtgatgatt
      421 tgatctaaac ttgctagcga caaagccatg gcagcaattt gacttaattg cgttaatcgg
      481 ttcttacgta ctgctggttc ttctgccatg accatcgtct gatcaaaata attttcgatc
      541 agtgggcgaa ggcttacaag ctgatcataa ttttcgttga tcgtttggtc agcaaagctt
      601 tttttcattg cctctactgc tttgtgcagt tctttctccg cttcattttc gaacagttca
      661 gggtctactt ctgattgttt ttcaagctcc gcttttttcg ctaagttcac gacacgtgtc
      721 aaagcttcca tcgatggttt gaagtcttca tctgcaagat gctgcttgaa caattgtgct
      781 gctgcaaata cttttgtcag atctttttgt tctgcattca aaacagcttc gatgacatca
      841 tgacgaatat tcttcgttgt caataattgg cgcagacggc ctttgataaa gtcgatcacc
      901 tgttgttgcc cttctgataa accaatgccg aaacgatccg tatctttact gataacatca
      961 ctaatcgttt cttgcagaac agacaaagga aaggcccatt ttttcgattc gatgatccga
     1021 acgacaccgt atgcttggcg acgtaaggca taaggatcgt ttgacccgct tggaatcatc
     1081 ccaactgcaa agaaagaaaa aatgctatct aatttatctg caatcgctaa aacagaacct
     1141 actgtagact gaggtagctc tccttcactg gatataggca tgtaatgctc acgaatcgct
     1201 gttgctacag caggtttctc gcctttcagc agagcatatt tttcgcccat gatcccttgt
     1261 agttcaggaa attcccctac catgttggtt actagatcaa atttatagat ttcagcagct
     1321 cgttgcagat ccatcaattc ttcctcagat agtcctactt gttcgccaat gatacgggca
     1381 atgacttgta cccgctgcat tttctcatag atactaccga ttttttcatg gaaagtaaca
     1441 gtttttagtt tttcaacgta ttggtcgatt gaagctttct tgtcttcatt ataaaagaat
     1501 tccgcatctt ctaaacgagc cgtcaatact ttttgattgc ctcgaaccac attttccaat
     1561 tttacccgat caccattacg agcagaaata aaatgaggaa gcagcatacc ttgatcgttc
     1621 cgtacctcga aataacgttg atgttctttc atagaagtga ctagtacttc ttcaggaaca
     1681 gaaagatatt tttcttcgaa gtcgccagaa aagacagttg gatattcgac taaattgttg
     1741 acttcttcta gtaaatcttc gtctagatca ataacccagt gatttttttc ggctaattca
     1801 tttgcttgtg taacgatcat ttcttgtctt ttttgcggtg aagcaataac gaattgttca
     1861 ttcaattttt cttcatattc ttttgcatgc gcaaatgtca catcttcgcc taagaaacga
     1921 tgtcctcgag aggctctgcc tgttttgaca tctaagatct caaacgggat tacttcgtca
     1981 tctaacaatg ccacgatcca gtgaataggg cggatatatt caaaatcgta ttctgcccaa
     2041 tgcatcgtta ctgggaaagt gaggctttta atgacatctg ctaaacctgt caatacttct
     2101 ttcgcttctt tgccgtgagt gtatttcgtt acatagacat attccacgcc ttttaattct
     2161 ctaaaagtga tagcatctgt cgtcagacct tgtccgcgga caaatccttc agctgctttc
     2221 gtccagtttc catctgcgtc caaagcaatt tttttggctg gtcctttgac ttcttcttca
     2281 ctgtctgctt gacgttctgg aatgtttgtt actttgattg ctaagcggcg cggtgtagaa
     2341 aacgtttcga tcgtatcata agtcaattgg ttttcatcta aaaattttgc tgttttttct
     2401 tctaattgtt tcatgcttgg tgtgacaaca tgagcaggca tttcttccag cccgatttca
     2461 agtaataagt cttttgccat cttattcagc ctccttcatg ttttctggat ttgctgtgtt
     2521 tttattcaat aaagggaatc ctaatttttc gcgttctgcc acaaagattt tggctacagc
     2581 acgagccatg ttgcggatac gggaaagata acctgctcgt tctgttacgg atactgcacc
     2641 gcgagcatct aataaattga atgtatggct gcatttcaaa atataatcat acgctggatg
     2701 aacaagattt tcatcgatac agcgtttagc ttctttttca aaacggtcaa agttgcttag
     2761 tagcaagtct tggtcactta cttcaaaaga atatttggaa tgttcatatt ctggttgttt
     2821 gaagatctcg ccatatttca caccatcagc ccattccaga tcatagacac tttcaacttc
     2881 ttgaatatat gaagcaagac gttctagtcc ataagtgatc tcagaagtaa ctggtttaca
     2941 aggtagtcct ccgacttgct ggaagtacgt gaattgtgtg atctccatcc catcaagcca
     3001 tacttcccaa cccacaccgg cacaccccat cgatgggttc tcccagttgt cttcaacaaa
     3061 acgaatatcg tgttctaatg gatcaattcc taaaagacgc aagctttcta aataaagctc
     3121 ttggatattt tcaggtgaag gtttcattac gacttgaaat tgatgatgct gatacaaacg
     3181 gtttgggttt tctccataac gcccgtcagc tggtcggcgg gatggctcta cataagcagc
     3241 attccatggt tccggtccga ttgcccgtaa gaatgtatat gggctcatcg tacctgctcc
     3301 tttttctgtg tcataagctt gcatcagcat gcagccgttt gatgaccaaa atttttgtaa
     3361 tgttaaaatc atatcttgga cggtcaattt tttactcatc tgttttgccc ctttcaattt
     3421 ttaagcgttg ctgtcaataa gaatacagga aagaaaacga caaaaagtcc ctatgtctga
     3481 ttacagacat agggacgaat aatttcgcgg ttccacccta cttccgaata aagattcggc
     3541 agcttcattt atcgtactcg caagtgcctc ttcaaaaatc gtttgggtcc ggcttccact
     3601 ctcccgaact cgctaaacca cgtgtttttt actgatcttg gtcaatgtac gtattcattt
     3661 tgcagttttc ttgtttatat aatagatcct ctcagtgaac gatctattta atctacggtt
     3721 aataatagac ggaagtccct gtatttgtca aatagttttg atttttttgt tgtatctttc
     3781 atttattctt ctttttcagg tatctctttt tcaggcatat ttttctctgg cgtctttaat
     3841 acgtgtgccc aagacttcat ttgatcaatg aactttttgc tttttagatg aataccgaca
     3901 tattcatcat acaactggtc aatgaggtca cggattgcct gcttcgtttc ttctttcaag
     3961 tggattccac tgatcttatc ataagaaata gccgaaaaca ttcgaacgaa ataaacagcg
     4021 cgaggatctg catgataacg gtgttcgtcc attggccagt gtttctcgca tatcacaccg
     4081 ccagatttgg aagaatagtc aaattttcct tttgtttccc cgcatacgac acagtgcgtc
     4141 caaattggcg cgattccgaa gcgttgcagt atttgaactt caaagatatt cgtgatgatt
     4201 tctgcatcat ctccttgatc catccgctgc agagcttgtt gcgtaaattg gaataaatgc
     4261 gggtcatatt gatgatcttc gattgctgca tctactagat ttagcaaata ggtaccataa
     4321 ccgctcaaaa agatatcttc ttggatgttc cgaaacgcat ggacgtcttt gacactgctt
     4381 aaaaacgaca aaccttcact tcgaaaatta ccgatataga ctgcttcggt aaaggggagc
     4441 aaagccggag ctaatggctg attttgccga tggattcctt tgatataaaa catcattttg
     4501 ccagaagatt ccgtaaagat tttgactaat ttatcttttt ctttgtaatt acggctagat
     4561 aaaatcaagc ctttcgattc tgcaagctgg ctcatattct ccctcctaaa aaataaatct
     4621 ggaaaagcag attctgccga tccagattat ttatgtttcg atcttccgcc gtttttctca
     4681 acgtgcggat ttttatccag tttatttcta tacttaacct ataagaagtt cagaatatca
     4741 gtattcgtct tttcggtagc caaagtcttg cagatagact tttttgtctc gccagtcttt
     4801 ttggactttg acccaaagtt ctagaaatac tttgtctcct aaaagatttt cgatatcctt
     4861 tcttgctttc gttcctactt gcttcagcat ttttccgcct ttgccgataa tgattccttt
     4921 ttggctatct ctttcgacga tgatcgtggc ctggatatgg attttatcat tctcgtttcg
     4981 cttcatcgaa tcaacaacga ctgcgacaga atgaggcact tcgtctcgtg ttaaaaacaa
     5041 gactttctca cggatcaatt cagaaacgat aaagtattca ggatgatcag tcacttgatc
     5101 atctggaaaa tattgtgggc cctctggcat ttcactgact aatacatcca ttaagcgttc
     5161 gacattgttt ccttctgtag cagagatcgg aatcacttgt gcaaaaggca tctgcgtcga
     5221 ataatcttcg atgattccca gcaactcgtc tggatggatc ttatcgattt tattgataat
     5281 cagataaact ggagaatgca cgttttttag acgttcaata ataaaatcgt ctccccggcc
     5341 gcgtttttga tcagcactga tcataaataa gactgcatcc acttctttca acgcactgta
     5401 agctgcttct accataaaat ctcctagacg atgctttggt ttatggattc ctggtgtatc
     5461 gataaaaatc agctgagctt ctggtgtagt atatactcct tggattttat ttctagttgt
     5521 ctgtgccttg tcactcataa tggcaatttt ttgacccacg attcggttca ataatgtgga
     5581 ttttcctaca ttcgggcggc cgacgattgc gacaaaccct gatttatgtt ctggcatata
     5641 cgttctcctt tttaattaaa caacaaatga tatattttag ggacaaataa aatcaaccca
     5701 atgatgacag caaaacaagc ggtcactaaa actgctccag ctgccatatc tttgattttt
     5761 ttcccaatcg gatgaaaatg aaaatccgta aacatgtcca ctacattttc aaaaacagta
     5821 ttgatgatct ctactatcca aacgagaaaa acagctaaaa gcagccataa ccactctatc
     5881 cgatcaagct ggaaaatcac gcccataaat aaagcaagga taccgaacgc aacatgtttc
     5941 ctcatattgc gttcttcctc aaaaacggtt ttgactcctt ggacagcaaa ttccacagac
     6001 atcaggaaat gtttgttttt ctctacgttt ttatcttttg agtccatagg catccaagat
     6061 ctctttctgt aaaccaaaca tttctttctc atcttctggt gtcatatggt catacccgtt
     6121 gatatgcaag aatccatgta ccgctaaaaa gccaagttcc cgatcatatg aatggccgta
     6181 agcttctgct tgttcagcag cacgttcaat agaaatcatg atgtctccta gtacacgagg
     6241 caaaggattc tctccatctt caaaaatcac tgggatttcg tcttcgcctt cttcttccag
     6301 agcaaaactg atgacgtctg tcggtgcatc ttttccacgg taatcacgat tgattacttg
     6361 gattgccgca ttgtccatga aagtaacaga catttctgtt tcctctggca gctttaaata
     6421 agatgctgca aattgcagca agtcatcgat ttctttcatt ttctcttctg agacttggtt
     6481 tgtttcatcc ataaaggtaa tatccattat acatcgcttc tttctattct tcttgttctt
     6541 cctttatctt ctcaacttct gttttcattt taggatattt gatccgagaa tggaaggtgc
     6601 tacttaaacc gctgatcaat gatttttcca cttttcggat ttctttcaag gtcagtccac
     6661 tatcgtctaa ttgaccatcg gaaatacgct cttcgataag attatggaca aaactttcga
     6721 ttttttcgct cgtcggatga tccattgccc gtactgcagc ctcacaactg tcagcaatat
     6781 tgacgatccc tgcttcacga ctttgcggtt ttggtccagg ataacggaat tgctcttctg
     6841 ttacttccgg attgcgttct ttcgctttga tgtagaaata acgcattagc gtggttccat
     6901 gatgctgttt gcaaatatcg atcaccattt gcggcatatt ataatcttcc aatattttgg
     6961 ctccatctgt cacatgtcca aagataatat gtttactgtc ttctggcaat aagaaattgt
     7021 gcgggttttc cgctcctgaa ggcaagttct caacgaaaaa gctagcatgt ttgatcttgc
     7081 cgatatcatg ataatagcaa gctactcgag ttagcaaaga acgtccgccg atttctgcta
     7141 cagcgttagc acttagatta gctaccatca tactatgatg ataagtacct ggcgcttctt
     7201 ccagcaactg tttcaataaa ggatgatttg gattgctgag ttcatttaat acaattacac
     7261 tgtcatcatt gaccatcaat tcaatatatg ggtgtagacc gatcgtcagc aagaatgaga
     7321 agagtgcacc agtgaacccg cagacaagca ttaaccaagt cgttgcatca ccaaagctca
     7381 ttccttgata gacgatcaaa atgacatcca tcatcacagg aaaaataatg acccacatgg
     7441 cagcagataa tccttgttct gagatccgtt tgcgtctgac aatcgttgcc atgagcccag
     7501 agaaaacata agacatcaag ataatcgtta gaaagttcgt gccaatcgaa tcataaaaaa
     7561 tgaaaagtgc agatactgct tggaaaatac cagccatgat ccctgctctt cggttcaaga
     7621 aaaagcttaa aacaagtggt gcaaaagcag cgggataaaa cagcgggata taagtagctt
     7681 gttccgtttg gaataattgg aaaaatttca tcagcactat gctgactgac atagctgtca
     7741 catagaaaag cacgtatttt gttctttctc ctgcattttg gaattgaagt gaattataaa
     7801 tcagtacgcc gatttgaagc aaaacagcta aaaccatggc aatgagtggg aaaatcgaag
     7861 tcgtttgatt cgtcaatcct agtaattcca attttttcat cgctgaagca tcaatttgat
     7921 ttccttcgcg aacaatgatt tctccttgga agatcatcac tggttgtaca gcttctcgtg
     7981 cagattgttt taattcttct gtctttttct cattcaatac atcattgact acaatgcctt
     8041 gatccactaa gtagcgaatc atttgttgct gctctgttgt gacattcaaa tactgaatct
     8101 gatcttctgc ttcttgttta aaagcttcca attcgctttc acgaacttgt ttactcatct
     8161 gttcgtcaat gagcttcaaa ctttcatccc taaccgtgtg aatttccgtt tcagtcattt
     8221 caaatatcgt cgaataaaaa ttgttcggca gtttttggta aaacgcaacg ttttctgcat
     8281 tcacgttttc aaaatttttc ttcagtgtag caatccgctc ttctgtagta ggtttcggga
     8341 tattttcatc ttccttcgcc ttatctacct tgtcattata agatttgttg atggtatcat
     8401 tcgtcttatc gatcaattcg aataattgct tgatccgatt gttctggtca tctgccagat
     8461 ctttttgata agtatattct ggagtcactg cttctgctgc cagttttctt ctttgttcgg
     8521 tttcttccgt gttctcgatc gttttattcg cacggatact ctcttctgct acttggcctt
     8581 ctctgaaatc attggccttt tgtttgacac tactaaatgt aacgccgcag acaatgataa
     8641 aaaacaagaa cagaaggaaa ggcaatgctg cctttccgag tttttcttgt agtttctgca
     8701 gtgttttatt caacatgtgc ttatcctcct aagcaaagct tattcttgat gaagatccgc
     8761 cttttcataa gctttgatga tttcggcaac tacagggtgc cgaacaacgt cacttgcttc
     8821 aaaattaaca aaatcgattt ttttgatttg ctttagtgtt cgttctgcat gaacaagacc
     8881 acttgtcgtc cctcgaggca agtctatctg acttgtatcc ccattgacaa tcatttttga
     8941 ttgataaccg agacgggtca agaacatttt catctgagcg actgtcgtgt tttgtgcttc
     9001 gtccaagata acgaatgcat catccaatgt ccgcccccgc atgtaagcta atggtgcgat
     9061 ttcgattacg cctcgttcca tcaatcggtt cgtatgatcc aatccaaaaa tttggtataa
     9121 agcatcataa acaggccgca gataaggatc cactttttct ttcagatccc cgggtagaaa
     9181 gcctaggttt tcccctgcct ctacagcggg ccgcgtcaaa atgatttttt gcacttcgcc
     9241 tttttttagg gcagcaattg ctaatactac ggcaagaaac gttttccctg ttccggctgg
     9301 ccctacacca aatacgatgt catgtttggc taccgattca acgtatttct tttgaccgct
     9361 gttttttacc cgtataggtt ttccattacg gtctttgacg atctcttcct catacatctc
     9421 aacaaaataa tctaatgtac ctttttgccc cattttcaat gccgtcacga catctggtgt
     9481 acttacgtgg attcctcgtt tgatcaattc ctgtaatgtc cgaatgactg aggcagccaa
     9541 ggaaatctgg gattgttcac caatgatctg aatgatttct ccacgtgtat ggatggttgt
     9601 ttccgttgtt tcctcgatca gttttatatg cttgtcgtgt gcacctaaaa gcatgctgac
     9661 atcatcagca gctgtcaatc taatctctaa agaactagac tcttccgtca aaaatagaca
     9721 tccccttttt ttcgattcat tctttcctat tttaccatac tcagaagaaa ctatatagca
     9781 aataagaaaa ggttgtaaaa gagtcgttta accatacgta ccaagaaacg ttaaaaaata
     9841 gctgtttcca ttcgctaaag gtctcgtttt gataaaaaga atctgagaat gtaagttata
     9901 tgaaagtgga gaacaaaata ttccgtttca ttcagaggta ttctctaggt atttttcttg
     9961 tttcaaaaaa agaaaacaaa atagttaaaa tattcttgca tttcaaaaaa aacaggtgta
    10021 ttattacgtc aacaaataaa catacagcaa agcgtcgagg aaaacagtag gctattcaac
    10081 gatttattcc cagtgagtca tgtaagtgag aaatgacaat aaatcgaata gacgaacatc
    10141 atttccgagt caatgtcgaa aacgtagatc attgtggctg cctccattat caggctagcg
    10201 gataacttta tcaaaaagcg tccgtgaatg aagaagcttt tttaagcgaa aaaaggtggt
    10261 accgttctag aatctagagc ccttttccca agtggaaaag ggcttttttt tatattttaa
    10321 ggtggtggtt ttcatggaat ctgatattag tggcattact aattgctgca acgtttatat
    10381 cgtcaatcaa aatgataatt attggaggaa aaatttatgg aagaaacaaa aacttattca
    10441 tggaaacaac tattgatggt cagttcactt atcttcggga tgtttttcgg gtcaggtaat
    10501 ctaatctttc ctgtccactt aggtcaaatg gctggcgcaa actgggtcag tgctggcgta
    10561 ggatttgcca tctcaggcgc tcttttccca ttactagcta tcttagctgt agtagtgaca
    10621 aaaagtgatg gtctgtatga cttagctaaa cctgtcggaa aatggtatgc tgccttgttc
    10681 ttaatccttg ttcatttgac gatcggacca tttttcggta caccacggac agctgctact
    10741 gcttttgaaa tggctgctaa accatttttg cctgaaaaat ataattcatt aggtatgttt
    10801 ttattctctg ctcttttctt tttacttgct tatttcctta ctgtccatcc cacacggttg
    10861 gtcaaatacg tcggaaagta tctaaactcc ttgtttcttg cattattagc aatcattttt
    10921 gtcgtttctt tattccaccc aatgggaaat ctaaatcaat ctgctgcaga tacttaccaa
    10981 acaaacgctt taacaaatgg tgtcctagaa ggttataaca cggttgatgc agtagccttg
    11041 cttgccttaa gtgtcacttt tgtccatgca gtccgtgacc ttggtttcaa agataaaaaa
    11101 gtcacagaat taacagcaaa agctggtagc ctgagcgttg cgctagaagt catgatctat
    11161 tttggtcttg ttcttctcgg tgcgatgagt ttgaataaga tgtctttatc agaaaatggc
    11221 ggaactgcac tttctcagat cactaatttt tatttaggta acttcggcgc tagcttctta
    11281 ggagtgatgg tcacattagg tgtcttcact accgctatgg gactcgttgt ttcttttgca
    11341 caagatttcc ataaactgtt ccctaaagtc agttatatga catggctgcg gttaacgact
    11401 ttcgtctctt ttgtcgttgc aaatgctggt ttggacaata tcatccaatg gtctttacca
    11461 gtattgatgc ttttgtatcc attgtcgctt gcgttgattt tgctttcctt aacagcaaaa
    11521 tttttccaaa agacaccatt tgtctatcaa gtaacgatgt tgtttgctgc tgttcccgcc
    11581 gtattggata tgctggcaaa ttcgcctgct ttagtgagtc aacaaagagt tgtagcaagc
    11641 atgctcgaat tttatcatca tcacgttcct tttgctgcat tgggacttgg ctggatggtc
    11701 ccaacgttac ttgggtatgc tggcagctta ctcttctatt acgcctatcg cctatcaggg
    11761 tataaacaag aagcaaatga actaccagaa gaataaccag atcaaacaca atttaacata
    11821 agaaatatta aacaggaaaa aaacagctag atgaaagaat cctattcttt cgtctagcta
    11881 ttttttagat ctctttttta cgagcacaaa aaaactgcgg acaatgattg tccgcagttt
    11941 aaatgataaa attaagattg taatagttct ttcacaatgg catttacttg gtttccatct
    12001 gcttttcctt tgactttagg catgatcgca cccatgactt tgccaaattc tttcattgat
    12061 gaagcaccag tttgcgtgat tgcttcttga acaagttgtc gaatttcttc gtcggaaagt
    12121 tgttccggca tgtatttttc gactatcaca atttcacttt ttactttttc agctaaatcg
    12181 tcacgtcctg cttcttcaaa ctcatgcaaa gaatcacgtc gctgtttcat ttcgcgagac
    12241 aacaccgtta attcttcttc ttctgtcaag tcgtgacctt ctttaatctg ctcgttttgt
    12301 atagatgact tgatcattcg gatgacttgt aaagattcct tatctttcgc tttcatcgct
    12361 gttttcatgt catcgtttaa tctacttagt agtgacacac taccaactcc aattcatcac
    12421 agaactagaa ttttttgcgt tttctagctg cttcagattt tttcttgcgt cttacacttg
    12481 gtttttcgta gaattcacgt ttacgagatt cttgtaaagt acccgctttt gacacggaac
    12541 gtttgaagcg acgaagagca tcgtcaagtg attcgttttt gcgaacgact gtttttgaca
    12601 tgttaattcc ctccctccga gcttaaaaag taaccgtaat tgttattgaa atatatctca
    12661 aaaaacaaga ctgtcctgta aatattatat ctaatgctgt tttgaccgtc aaggaaatct
    12721 tgcttttttt taaaattatc aaatgttatt ttatttaaat ccttattgac aattttcaca
    12781 tcttccgaaa atctcgaatc tatgcccttc gatcgtacat ccaccgagct gttcttcgaa
    12841 ataattcatt ggacacatat ggatttcttt cgttgttccg cacaccgtac agataaagtg
    12901 atggtgatgg ccgatttccc cttgacagca atgaaaacga aacttcatct ctccatttaa
    12961 atcggtttct tccagtaaat cgatttctgc aaaatcatgg agatttcgat aaatcgtatc
    13021 gtaacttact cctttgaatt cctgattcat atagtcaaaa acttctttag cggatacgta
    13081 gcgattgcgc ttcactaaat aagttaacaa tgcttctctt tttttagtat atttaaaacc
    13141 gttatttttc aatgtttcta gtgattgttc gatcaacgtc tgttttttca tgacttattc
    13201 ctccaaatca aaatgattac gaagtacaca ttctagagta tggtataata aacataaaaa
    13261 aaatgcaagt gaggttttat ccatgtcttc cgattctaca gaaatcgtta ctttttttgt
    13321 catctccgac tctgctggag aaactgcgac aaaactagcg caagccacta tggcccaata
    13381 tcctagcgtt gagttcaatt tattccgcag aacatttgtg acagatgaga aaacattgat
    13441 gcaggcactg caagatgcac tagaagaaaa agctcttgtc ctgcacacat tgatcaatca
    13501 agaattgatc gagatgacgc gttctttttg tgaagaacat caattattta gttttgatgt
    13561 gatgactccg ccgatatcag aaatcgagcg cttaactggt atcaagccca ttcggcaacc
    13621 tggcgccctt catttattga atgagaacta tttcaaacgg atcaaagcaa tggaatttgc
    13681 tgtaaaatac gatgacggga aagatcctcg tgggtttcta gaagcagatg tcgttttgct
    13741 aggcgtatcc cgaacttcca aaacgccttt gagcttgttt ttagctaaca aaaatttaaa
    13801 agttgccaat ctacctttga tcccacaagc acatattccc aaacagcttt gggagatcga
    13861 tcctaaaaaa atcgtgggac tgacgaataa cccagatatt ttaaacaata tccgtaaaga
    13921 acggatgcgc tcttacggat taaatcctga tactgcttat tccgatatcg aaaaaatacg
    13981 agctgaactc gattttgcga atgatcttta tgaaaaattg ggctgcgtag taatcaatgt
    14041 cgcttcttta tctattgaag aaacagcttc gcttattttg aatgctttag acctagaaga
    14101 ccatagttat tatggaactg aaaccaccga agaaacagac taacaatttt tctttaaaaa
    14161 aactggactg tgtcagcgaa gaagattcgt tgacacagtc cagtttgtct ctatttgcac
    14221 ctatcgttat tgatgttcca catgtttgag tgtctggttc aaaatatcca gtacgtgaga
    14281 atcatcaaga ctatacaaaa tcgcttttcc ctcacgatgg gacttgacga catggttttc
    14341 tcttaataaa cgcagttgat gcgatacagc agattgttcc atttccactg cttggatgat
    14401 tgctgtcaca ttttgttccc cgtctttcag atacagcaga attttgagac gagtggggtc
    14461 actcaacatt ttgaatagtt ggctgacttt ctctactttt gttttttgcg tgtctggcaa
    14521 tccattcacc tccaacttga aaaaagactg acttctaaag tttaccactt tttccatcag
    14581 tctcaagttt ttttattctt ctgtcatctt ttggataatc gtttcataag cggctacttt
    14641 ttcagctgcg tcttctgaag agtttccttt tacaccgata taaaatttga ttttcggctc
    14701 agttcctgaa ggacggatag cgatccagcc attttcttcc agcgtatact tcaatacgtc
    14761 agatggcggt gtcgttagtt tttctacgtt tccttcacgg tctgttctcg tcaactcttt
    14821 gaagtcttct gtttggatga cttttgctcc ggcaaattct gttggtgctt cttcacggaa
    14881 tttttccatc aaagcagaga ttttcgcaga accttcttgt ccgctcattg tcacagaaat
    14941 cgttttttct gcgtagtagc cataggtttc aaaaatcgtt tgcaagccat catacaacgt
    15001 tttgccttgt tttttatagt aagctgctac ttctgctaat aagagcaatg cttggatcgc
    15061 gtctttgtcg cgaacgaaag gtttaactaa ataaccgtaa ctttcttcga atccgaacat
    15121 aaaagtatgg gaatgatctt cttcaaattg ttgaattttt tcagcaatga atttgaatcc
    15181 tgtcaataca ttgaacatgg tagccccata gtgttccgca attgctgtag gtaattcgct
    15241 agaaacgatc gatttcaata ccgctgcgtt ttcaggtaaa gtgcctcgcg attggtgtgc
    15301 ttccaaaata tattgagcaa acagtgctcc gatttggttt ccggtcaata cttcatagga
    15361 gccatttggc aaacgaacgg ctgcacctaa acggtctgca tcaggatctg ttgcaatcag
    15421 caaatcagcg ccttctttct cgccaagtcg tatcgcatac tcaaaagcag agtgttcttc
    15481 tggatttggt gatttgactg tagtgaaatc tgggtctgcg acagcttgtt ctggaactag
    15541 tacgaattgt tcgaatccag cttgtttcaa cgcacgttcg cccaacattt ttcctgttcc
    15601 gtgaagtggt gtgtacacaa gtttcaaatc tttccccatt gtttccacca attcatgatc
    15661 aatcgttact gctttgattt cttctagata agcggcatcc acttcttctc cgatgatcgt
    15721 gatcaatccg ctatgttcag cttcttcgtc agataatact tcaactttta acggattgct
    15781 gacttcacgg acatatttcg tcaatgcatc tgcgtctgca ggaggcattt gtcccccatc
    15841 ttctccgtag actttatatc cgttgtaagc tgctggattg tgggatgcgg ttaccatgat
    15901 tcccgcaaac gtcttcaaat gacggactgc aaaagaaagc tctggtgttg gacgtagact
    15961 ttcgaataca taagatggga tattgtgatg tgctaatgtt ttggctgctt ccatggcaaa
    16021 ttctggtgat tgatggcgtg agtcataagc gatagcgaca cctcggcgtt ttgtttcttc
    16081 gccttgtgta tccatgaaac gtgcaagtcc ttctgttgct tgtcttaccg tatagatgtt
    16141 cattcgattg atcccaggcc ctaagattcc ccgcatgcct gcagtaccga attccaacgg
    16201 tgcataaaaa gcatcttcaa gtttttcagg atcttcaccc agatcattta attgtttttt
    16261 taagttttct tctaaatttt cttcatgtac ccattgttca tacacttgtt cccaagacat
    16321 gaaaataaca cctctttctg aaatatggtt cttaataagt atagcattca cttattagat
    16381 atgaaagtat gaggaccaaa aaacgcttaa atcaagaaag gattctttta tcaagcacgg
    16441 ttgcaagtat tcgcataaat cggattcagt agatttcacg cgaaaaaaaa gagtaaaaga
    16501 acaattaaac cgttcttcca ctctttttaa acttatgcag ttgtttcttc taaagattcc
    16561 aagtatttat acacttgttg tccagcgatc ccaccatcac caacagcagt agtgatttgt
    16621 cgcaaatctt tttcacgaac atctccgatg gcaaaaacgc ctggtatatt cgtcttcatt
    16681 tcgttgtctg ttggaatcca gccagcttcg ttcgtcaacc ctgcttctct aaatggtgca
    16741 gttaatggat ccagtccaac atagatgaat actccgtctg ctgccaaatc aaactcattg
    16801 ccggttttga cattacgtgc tttcacacct gtcactacca tttcattccc aacgatttcg
    16861 tcaacgactg tatcccacat aaaggaaatt ttttcattcg caaatgcacg gtcttggatg
    16921 atcttttgtg cacgtaattc atctctacgg tggacgatga ctacttcaga agcaaattgt
    16981 gtcaaataga tggcttcttc tactgctgag tctcctcctc cgatcactac tagacgtttg
    17041 ttacggaaaa acgcaccatc acaaactgca cagtaagaaa cgccacgtcc agcaaattct
    17101 tcctcgccag gtacgcctaa tttacggtgg atacagcctg ttgcgataat gactgttttt
    17161 ccttcgtaag ttttatcttc acaaataact tctttgtggc tgccgtgatc cttgatatct
    17221 tgcacgattc cataagcatt ttctgtccca aatcttgaaa caccttcata catcttataa
    17281 gctagatcag gacccattat tgaatcgaaa ccaggatagt tttcgatttc tgccgtattg
    17341 ttcatttggc cgccaggggc gccttgttcg atcatcaata cggataagtt tgaacgtgaa
    17401 gcatataaag cagcagtcat cccagcagga cctgcgccaa taacgattac atcatacata
    17461 tgtagattct cctttactta atcaagtaag catactttac agccaatgcg aaaaaaagtc
    17521 tattgttctg cttgcgtttc tcgaatagct ttattatact cgaaaaatcc gctgaaaaac
    17581 aatagacttt tataaatcat tgatcaatca ttcgaaagat tttctccatt tgaatcaatt
    17641 acttttttat accagttgaa tgatttcttc ttcgaacggg ctaatgtgcc atttccttcg
    17701 ttgtcacgat cgacataaat gaatccgtac cttttcttca tctcacctgt accagctgat
    17761 actaaatcaa tacatcccca agtcgtatag cctaatagat cgactccatc taattctact
    17821 gcatctttca ttgcctggat atgtgctgcc agatagtcga ttcgatagtc atcttccaca
    17881 taaccattct catcgggcgt atcgactgca cctaagccgt tttctacaat aaatagtggt
    17941 ttttgataac gatcataaat atcattcatc gttattctca agcctaatgg atcaatttgc
    18001 caaccccatt cacttgcttc cagatatgga tttttgacag aagcaaagat atttcctgca
    18061 gtctgttcca agagttcgtt gtcagtagtc gaaactcgag aagaataata agaaaaggag
    18121 ataaaatcaa cagtatgttc tttcagcaat gcggcatccc caggttccat tttgatctga
    18181 atgccatttc gttccatttc tttcaatgca taagcaggat attctcctcg tgactggaca
    18241 tcaatgaaga aataattttc tcgatctgat tttctagaag cccaaacatc ttcaggattg
    18301 caagtgtatg gataatatgc tcctgctgcc agcatacagc ctactttgtt ctccggatct
    18361 acttcatgag caatcttcgt tgcgatggca cttgcaacca actcatgatg tgccgcttga
    18421 tatttgattt gttcttcatt ttctccttct tcaaaataca gccctgcgcc catgaatggt
    18481 gcatgaagga tcatattgat ctcattgaat gtcaaccaat atttgacaag tcctttatag
    18541 cgattgaaga tgactcggca cagattttca taaaaaccaa cgagttctct ggaacgccac
    18601 gcaccatatt ctttgatcaa atgcatcgga caatcaaaat gtgtaatcgt cacaagcggc
    18661 tcgatcccgt acttttgaca ttctttaaag acatcctcat aaaatttcaa accagattca
    18721 tttggctctt tttcatcgcc cattggaaaa atacgactcc aagcaatgga catccgataa
    18781 gtcttgaacc ccatttctgc aaataaagca atatcttcct tataatgatg atacatatcg
    18841 atcgcaattt ttgctggata aaaatgattt tcatcaaatt caaacatttt cttttttcca
    18901 gtaatgacag gaaaacggtc ttctccgatt ggcacaacat ctacgttcgc taacccacgt
    18961 ccgccttcat cataaccgcc ctcgcattga ttggctgctg tagctccgcc ccataaaaaa
    19021 tcttttctga atcccatcat acttcctcca ttacatgtgt attgcttgat aattctcttg
    19081 ccagttcatc ttggacctcg attccttctg cttttaaccg gctgattgtt tccttgaatt
    19141 gcggtaaata ctgctgatgt gcaataaaca actcattcat gatccgtttt gctgtctttc
    19201 ctgatcgtat aagcggattg atcgtaaacg cttgtaaagc tgttccataa tcaccagtca
    19261 cagctgcttc gatcgtcagc aattccatat tcttcattac ttgcaaccag cctctttcag
    19321 cagcaggaag ggaaccaaac gctacatttc gtgcgccttg tgcgccaaca taggcagtga
    19381 cttctactac acaatctgcc ggcagatcag gaacagctcc atcattcttt gtagatacca
    19441 cgatctgtgt ttctttattt ccatagatcg aagcaatcgt ttcacaggca gcatctgaat
    19501 aataagcacc acctcgtttt tgcaattgtt caggtttatg atccaattct ggatctttgt
    19561 ataattcaaa cagctctgct tctgtttctt tcacttgctg cgctcttgta ccaatcgttt
    19621 gatattcttc taaagcatgt tccagcattt cttcttcacg gtagtaatag cggtggtagc
    19681 cacaagggat catgttcatt tgttttaatt gttctttgaa aaacgggata tcaaagatat
    19741 ttttcggcaa tccattgtct tcatcgtata aacgatcaat caattctgcc gtgcggtcat
    19801 ttcctttatt atctgctact ttgtgccaat ggaagtgatt tagaccggca aacttgtaga
    19861 tcagctcttc ttttttcttg ccaagcattg ttggttctgt catcatcgcc attactggca
    19921 cattgcataa tcctatcact ttatcccatt tgccatatct gataactgct tctgtcacca
    19981 tcccgcttgg gttcgcgaaa ttgatcagcc aagcatttgg acataaacgc ttcatgtctt
    20041 caacgattgc caaaaccact ggaacggtac gaaaagcttt gaatatcccg ccagcaccat
    20101 ttgtttcttg cccaatcatc ccataataac tagggatccg ctcgtctttg attcgtgcat
    20161 ctaattgacc gacacgaaac tgagtcgtaa caaaatccgc atctttcaat gcttcttccc
    20221 gatccagagt tgcatagatt ttgacttcat acggagaagc atcccacata cgctgagaca
    20281 tctgactgac gatctcaagc ttttcttttc cttcttctac atctacgagc cagatttctc
    20341 gtatcggtaa ttcctcatat cttttgataa atccttccat caactcgggg gtgtaactgc
    20401 tgcctccacc aatcgtagcg attttgattc cttttgccat gttctcactc ctttactttt
    20461 tacactttta ttatcttttt tgtaaacaaa acaaacaata gaaattcgtt tctttccagt
    20521 aacatttaca aaagttagtg ttttctactg gatttttgta aatatcttgt caaaaaatgt
    20581 ctttattaag ctatataaca taaatccgtt tacaaatcat tttcaaaaaa gttataattt
    20641 acgtaaaaaa acaagaagaa ggtatctaca tgttattacg tgaaaaaatc aaagaaatct
    20701 ccttttctcc ttcagaaaat gaagtgattc agtttctctt aagcgattct ccagcacttg
    20761 gcgaaatgac catccaagag attgctgagc gatgttatgt ccacccgtcc acactcatcc
    20821 gtgtagcaaa aaaaatgggt tttgatggct gggtcagttt tcgtaatgct tttttagctg
    20881 aaacagccta tcttgaaggg aattttcaag acgtagatgc gaatcttcct ttttccacca
    20941 cagacggtat tatgacgatc gcaaataaaa tggcttcttt agaacagatg acgattcaag
    21001 atacactttc tctcattcat catgaccaac tgcaaaaagc caaacaacta atgcttcaag
    21061 caaaaaaaat cgtgattttc gccagtaact cgaatacttt gatttctcaa gatttcatgc
    21121 tgaaaatgaa gcgcatcaaa atggatgtca cgattgtcac cacttttggt gaatcgttct
    21181 atgaagcgta caattgcacg agtgatatgt gcgggattct gatttcttat acgggtgaaa
    21241 acaatgtgat ccttcgtacc gcagaaatat tgaaacaaaa tcatgttcca attttagctt
    21301 tgaccagtat cggtgattca acgctatctt caatgagtac agccgctttg cgacttacga
    21361 cacgcgaacg actgtattcg aaaattggta attttacgat caatacatcg atttgttatc
    21421 ttctagacgt gttatatagt tgtgtttttg cagaaaatta tcaacagaat ttagtccatc
    21481 taatttctgt aggacaaaaa tttgataaac gccctatcag ctcagccatc atgaaagagc
    21541 ctttcaattt tgaaaataaa gaagtggact aaaaagaata attaagccta gtccattctt
    21601 tcacctaacc gttcaggtca gtgcggtgat aagtgcatcg tctggcccga ccgtctcccc
    21661 ttgattttcc aaaatatcca aataatccgt gtaattggtg acgatcacag gtgtttctaa
    21721 actgtatcct tcctcttcga ttttcttttt gtcgaagcgg agcaacagat cgccttgttt
    21781 cactctttct ccttgctgca ccaagctttc aaaatatttc ccttccaact gaacagtatc
    21841 caatccgaca tgaatcagca attccagacc tgcttcagaa accattccga ttgcatgttt
    21901 cgtcgggaac agggtcatga ctgttccgtc aaaaggggca cgtacttctc ctttttcagg
    21961 gtagatcaag attcctcgac ctagtgttcc ttgtgcaaaa gctgcatcct ttgctgcatt
    22021 cagtggagcg atttgtcctt gtatcggtgt ttttacaatt tctttacctg atcttttctg
    22081 tctatcatct gtttcacctg cttcctcctt ccaaaagaaa aaagtcagcg caaaggatac
    22141 caccatcgca atggcgattc caatcaatac attaatcaca tccgttaaat caccatctgg
    22201 tctaatatag ttgggaattg taaagatgcc taatccacct ggattccaag aagttaaatt
    22261 cattaatcca ctatacgcgc cccctaacgc accaccgaca caggtaaaaa taaatatttt
    22321 tttacgtggc aatgtaaacc cataaatagc tggctctgta atccccacaa taccagaaac
    22381 aatggctggt attgcgattg ctttgtcttt tgggtttcta agcttaaagt agagtgcagt
    22441 aagtgctgca gtttgtccaa aagacactac tgcaacaggt gtcatgatat tttgccaacc
    22501 attcacagaa aattgcatca atcccattgg tacgattgcc caatggagac caaacatcac
    22561 tagaatttgc cagaagaagc ctacgattgc tccataaata actggcgaaa gtgctaaaag
    22621 tgtttcaaat ccagccatta aaatatcagt tgcgaatgtg aatgctggtc caacgagtaa
    22681 aaaacctaag ggcattgtaa taagaacggt gaagaatgga acgaagaaat tcgcgatcat
    22741 ctcaggtact aactttttaa ttggtttctg aatttggcta gctaacaaca caataaagat
    22801 aatgggaatg acagaagaag cgtagttacg cgcaatccag ggaatgccga atactgtttg
    22861 ataaataggt gcttcaaaaa tagtgccaga aaatatggta gtcagtggtg cttctgctgc
    22921 accactcaaa gcttccagcg acaagctagg attcattaat gctgccccaa gcaacatccc
    22981 tacgaattca tttactttaa atttacgggc agctgttaaa ccgataataa caggcataaa
    23041 ttggaataca gaatcaccga tattatcaaa cataacaaat gtgccagaac cgcggtcaaa
    23101 tgcgcctaag aagacaagta atgctgtcag tccacgaatc atcccaccag cagctagaat
    23161 agcaaggaat ggctggaaac agcccgatat tccatcaata agcatatcaa acggtctcat
    23221 tttttctgtt gaaacagcct catcaaaagt aaggtttcct gcttttataa cctcttcaaa
    23281 cacgactggc acatgattcc cgatgacaac ttggtactgt cctcccgctc gcattaccgt
    23341 cacaacaccg tccatatttt tcaagatctc atcatttgct ttttcttcgt tttttaattt
    23401 gaaacgaagc cttgtgatac aatgtgtcaa accattgata ttttccttcc cgccgacatt
    23461 ttctacaatt ttgctcgcta attcttgata ttttcccatt tctattccct ccaatttatt
    23521 agtggaaggt ttagccaact gaatgtcact acccttattt catgcgttct tgttaattta
    23581 tcctcctttt tttatttatt tacaacgatt ctcatgcact aaacgcgcaa tatggatcgt
    23641 taaatacatt ttttcgtccg tggacatctg gtagttgaat atctcggcta aaaagtctgc
    23701 tattttctca acgcaaccaa acgtatcctt atattttttt tgaataacct ggtacaattc
    23761 ctcagaaact tctcccactt ctgatttttc tccatctagg acgcgtgtca gaaaaaaacg
    23821 taggtgtgtg acgaatcgaa aaaaatggac tgaatcttca tcaaatgtaa tcttatagta
    23881 atagcggacg atatttagaa tatcctgtat tgttgtagta aacaggtagg tattgtcttg
    23941 ttggctttga atgccttgtg cattgactaa atgcaatgcg ataaatccgg cttcatcttc
    24001 tgataacttg atgtggtatt tatccgagat tttcttcact gtttttttcc cgatggcata
    24061 ctctttagga aatagttgtt tgatatcata cagcaataca tttggtacaa atattcccat
    24121 tttgtgacgt tcgatagccg tatacaaatg atccgtcaat gcaatataca ccgaatcatt
    24181 caactggact tgtagagcct cttttgtata ttcaatgatt tcacaagaaa tttctaagta
    24241 ctcaagagga atcgcttgtg ccaattcttg gaactgttgt gaaagtccgt catttgtcaa
    24301 ctgaaatttt ttgtcgatgc atgagtcaaa aatcgggtca cccactttct ttttgaatgc
    24361 caaacctttt cccatcacga tcatttcctg atttctttca tccctggtta ttacgacgtt
    24421 gttattcagt actttctcaa tcagcatgtt ttactccttt ccatgatata tagggctgta
    24481 tccaaaacaa aaagaaaaac ccaaaaagcc gtccatggaa ccatgggaga ctcatcaggt
    24541 ttagcttgca tcaggcaatc actatccaag ttgtatcgtt ttctttatat tatcgaaagc
    24601 aagcactttt gtcaacgctt tcttagcggc tattgggcac ttctgactag ctgtcgtgat
    24661 tttttttaaa tctggtaatt acgacactaa cgctcacaga tgaagaatct gggaagctct
    24721 gttttatttt cactctagcg cttaggtcaa aatgctacta tgctactgtc ccaacttcta
    24781 atatacggtg ttccagtacc agcttatcgg tgataagcca aatttatgca aaaatctgga
    24841 aagccttttt tacaattttt ttcttatcac ctaaagctga acggagccct gtcacaacca
    24901 ctttttacac accactgctt tgcagtttgt acatatctgc atacaaacca ttttgcgcta
    24961 gaagtgtttc atgattccca cgttctacta tatgaccttt gtctaaaact aaaatcaatt
    25021 ctgcatcccg aatcgtggac agccgatggg caatcgcaat cgttgtccgt ccttgtcgca
    25081 tttttgtcaa tccttcttgg atcaatcctt ctgtttcagt atcgatattt gctgtcgctt
    25141 catccaatac tagtatttta ggatctgtca cgattgttcg cgcaaaagtg atcagctgtc
    25201 gttgtccgct agaatagctg gcaccgtgtt cgatcacttt tgagtgatat ccttttggta
    25261 attcatcgat gaacttgttt gcttgaacaa actcagctgc atggcgaatc tgttcgtctg
    25321 tgatagttgg attcatcatc cggatatttc ctgcgatatc tccataaaac aagaaggcat
    25381 cttgcaagac caatcccatt ttcttacgta actcttccat tggatattct cgaatgtcat
    25441 gatcatcaat caagatctgg ccttcataaa attcgtaaaa ccgcatcaat acgttgatga
    25501 tcgagctttt tccgcttccg gtgtgcccca ctaatgcaac ggtctctccc ggattagcga
    25561 caaaagagat attgttcaat acattgtgct ctccatcata agaaaagctt acattgcgaa
    25621 actcgatctt acctgaagta atcgcttgat ctgctccagg attttgttgc ggtgcatatt
    25681 cttctgtatc catgattttc aaaatacgac taccggcaac cattccatct gtaaaggtgc
    25741 tcaaaaagtc catcatttga gacattggat taaaaaatcc ctggacatag gtcgtaaatg
    25801 catagatcag tccaacttct acgggagaat gcagcgcatc gatcccaaac aaagtcaacg
    25861 ccaacgcaat cgccaatgca tatagaaaat tgatgatcgg acttaacaga atcgaatttg
    25921 ttttgatcat cgcatagcgc gtgtctaaat actcgttgtt cacttgttca aattctttag
    25981 ctaaacgagc ttcttggcga aactgctgga taatacgcat gccggaaatc gattcattca
    26041 atttcgtgtt cagctgactt aatttttccc gcatattccg gtaaatacga gaactgaatt
    26101 tctggtaata ccagatgacg attcctaaaa tcggcaagaa caccaaagtc cacaaggcaa
    26161 tttctccatt gatttgaaac atggcaatga aggaagaaac gactgcaaag atcccagtca
    26221 ataccatcaa aaagacatac caaaattcaa atagcgtttc tgtgtcattt gtcactcgag
    26281 aaacagtcga tcctgccggt gtctgatcaa aataacgcat acctagtgta tgcagctttt
    26341 caaataatct tacccgaaca tactgatagg tcttcaatga agccatggaa tacaaatacc
    26401 attggaaaaa ccaaatgata cttttgacta tgactccaaa caagtacata ccagcaaaaa
    26461 acaaaataac ttgtgtcgta gccgactgtt tagccagatg atcatccata aaagtttgga
    26521 tgatccttgg caataggaca ttgatcacag acagggcaaa cgcaaataag atagcaacga
    26581 tgaacgttct tctaaaaggt ttggcgaact tcatcagtcg tttgatgatc ttcttctgtt
    26641 ctttaagtgg aatcgatttt gtccattccg attgataatt ttcatccatc aggcctcgcc
    26701 tccttctatc ttcgcttcta atttctgttt ctcccacatt cgttcatacc agccgcctaa
    26761 tgcaagcagc tcatgatggg ttcctcgttc aatgattttc ccttgatcga caacaatgat
    26821 ttcttttgca tgcatcacgc tgcttaaacg gtgagctgca atgatggttg ttttctcttt
    26881 tcttatttct tttaaattat gcaagatagc ttcttctgtt ttggcatcta ctgcagaaag
    26941 tgcatcatct aagatcagca attcaggatt tttgatcaat gctcgagcaa tcgaaatcct
    27001 ttgtttctgt ccgccagata aagagactcc acgttctcca actaaggtat cataaccttt
    27061 tggtaattcc ttgatttcat tgttgataaa tgctaaagaa gccgcatgct ctacttcttc
    27121 ttctgaaagt tttggattag aaaaacggat attatctcga atggtcatcg aaaacaagaa
    27181 gtgatcttga ggcacatagc cgattgatcc taataaagca ttcaatgaat attctttgat
    27241 cgaacatccg ccaaattgaa tttttccttg ataatcatcg tattcacgca tcagtaattt
    27301 gatgattgtc gtttttcccg caccagtttt cccaacaata cctaatgttt ctccttcttg
    27361 gatcgcaaat ttgatttgtt ctaatgctgg tgattcttct ttcggatagt taaaagagga
    27421 aatagctaca ttcagctcgc cttttgccgg agtctgcact gcacccagtt gttccacgat
    27481 atgcgtcttt tcatgcaaaa gttcattgac gcgatcataa gaagcatttc ctctttccaa
    27541 tacgttgaac aatcgaccaa tcgcaaacat cggccaaaca agcataccga tatagctaat
    27601 aaatgagacc atctgcccga ttgagatcgt gccttccaag acatactttc cacctaaaat
    27661 aattgttgca acataagaca gaccgataat caaggtaatg aatggatcaa ataaggagtc
    27721 taaaaaattg actcgtttgt ttttaataat tgcatcttca atcttttctt caaaatccgc
    27781 gagatcttct ttttcttgtc caaatgtttt aatgactttg atcccagtaa tactttcttg
    27841 tgtcttatca ttgatactag aaaaagcttc ttgcgaatca cgaaaagcat cgtggagttt
    27901 tgaccccagc actcgtgaag taacggctag taaaggcaga ggaatcagcg caatcagtgt
    27961 taagcgccaa tcaataaaca aaatcatcgc aatgatcgtt gttccgcccg tgatcactga
    28021 atctgcaaag gtcaagatac cagctcctgc tacattttgg attgcattca aatcattcgt
    28081 tgcatgagcc atcaaatctc cagtccgata tttttggtaa aagagattgt ccatttctgt
    28141 aaaatgtttg aatagctgct gccgaagttc tttctccaac cgagctgcac ttccccaaat
    28201 attcgtccgc cagatataac gaaaaagata ttgtaagaga gctgcaagga tcaataataa
    28261 gatccaccag gaaatgatct ttattgataa atttttatcg gcgatctcat caatgatgat
    28321 cccaatcact tttggaggag ctaactgtac caaggccact gcgaataggg agaaaatccc
    28381 aattaaataa tgtttctttt cctgtcgaaa aaaccaacct aattttctaa aaatcgacat
    28441 tttactcctc ctttgtcttt atcaagagca taggattgtc tgtgcttgtc ttttttgctg
    28501 aatagtctga atagtctaac aaattacgaa ataaaaaacg gactgaaaaa atcagcccgc
    28561 aaaaagtctt tgggtcagaa cctatttttt cccttggttc ttcatttgct gcatcatctg
    28621 gcgaattttc ttctcagatg gtttttgccc cattgacatc atcattgatc gcaacatgtc
    28681 ctcattaacg ggaggatttt tttctaaata gtctttcata tatttacgcg ctaggaaaaa
    28741 gccacctact gcgccgatta gcaaagcaat aatagcaata agtacgacaa tacctgttga
    28801 taccatataa atctctcctt tctatttccg aattgctctc aatgatttat tttactaaag
    28861 tttattgaaa aaagaaaggc gtattcttta gtttcatgca aaaaatagtg gtttttttag
    28921 agaagaacaa aatttctttc attaaccagc aagacacgcc acgaaaaaaa attaggcata
    28981 ccaaatcttt ttctttaatt ttttctttct gaggtgtaga atgtaatcgt agataaatag
    29041 gaaaggtggt tttttcttga ataatcaatc caacaaacaa tttcataagc atcgacttat
    29101 tgaacataca aatggtttat ctttagctga agtaaatgga acagtggatg tacccaaggg
    29161 aaaaagtttt tttaaaacac ttcttgctta ctctggacca ggtgcattag tagcagttgg
    29221 ttatatggat ccaggtaact ggtccacttc gatcactggt ggacaaaatt tccaatattt
    29281 attgatgtca gttattttga tgtctagtct gattgctatg cttttacaat atatggcagc
    29341 aaaattagga atcgtgaccc aaatggattt ggcccaagca atccgagcac ggacaagtaa
    29401 gacattgggt gtcattttat ggatcttgac tgaattagcc attatggcaa cagacatcgc
    29461 agaagtcatt ggtgcagcaa tcgccctcta cctgcttttt gatattccat tggtaattgc
    29521 cgtatttatc actgtgttag atgttttcgt ccttttattg ctgacaaaag tcgggtttcg
    29581 taaaatcgaa gctttggttg tctgcttgat tttcgtcatt ttattcgttt tcgtctatca
    29641 agttggcttg tctaaccctg attggcacag tttgtttgcc ggatttatcc ctaacagtca
    29701 cacattctca gactcaccgg tcatcggcgg cgaaactccg ctgactggag ctttagggat
    29761 tattggtgca acagtcatgc cgcataactt atatcttcat tcagcagttt ctcaaactcg
    29821 gaagatcgat caccaagacg aagaagatgt agcacaagcg gtacgctttt ctacttggga
    29881 ttctaatatc cagttgtcaa tggcttttct agtcaatgca ctgctattga tcatgggtgt
    29941 ggctgtattc aaaaccggtt ctgtccaaga tccttccttt tttggtctgt atgaagcttt
    30001 atctgatcca tcagctatga gcaatggtat cttgattgct gtagcaaaat ctggtatctt
    30061 gtctacttta tttgctgtag cacttcttgc ttctggccag aactctacta ttactggtac
    30121 gttgaccggt caagtcatca tggaaggctt catccatatg cgtatcccaa tttggctaag
    30181 aagactagtc acacgattgc tttctgtgat tcctgtattg atttgtgttt tgtttacaag
    30241 tacaaaagga acgatcgaag aacataccgc tttgaataac ttgatgaatg aatcccaagt
    30301 ttttctggct tttgcattgc cattctcgat gattccttta ctgatgatga ccaatagcca
    30361 agcggagatg gggagccgat tcaaaaattc atttgttgta aaactacttg gctggttctc
    30421 tgtgattagt ctgacttact tgaatttacg aggattacca ggtcaaatcg aaagtttctt
    30481 cggcgagcaa gccacctcag ctcaactagc attggctgat caaatcgctt atgtaatcat
    30541 tgttcttgtc cttctcctgt tggcatggac gattggtgat ttatataaag gaaacaaaaa
    30601 atatgaacag cgtttgcagg aaacgataga agaaatcgag tagaaactga ttcttttaca
    30661 caaaggaggt tgtgtcagaa gtgggcagct tcaagaaata agaaggaatt taagaaaatt
    30721 gcttttcaaa tttttgtgaa atttcggctt atttccgaag aagttacttc tggaacaccg
    30781 tgtatcagag gttgtgaaaa agctgccttg catcaagtaa taagaacagc caagtaaaaa
    30841 cagcttttta tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgagcac
    30901 cgtttattcg gaaaaaggaa ctgcgacaag acttttgtca cagttccctt tcctacgatt
    30961 agtcaagtaa aaggtgtaag aaaaatagct cataaacgaa agcgacaaaa tcaa
//
LOCUS       DASHXG010000031        29099 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.031, whole genome shotgun sequence.
ACCESSION   DASHXG010000031 DASHXG010000000
VERSION     DASHXG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.031"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..1030)
                     /locus_tag="U2R59_001625"
     CDS             complement(<1..1030)
                     /locus_tag="U2R59_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8966016.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="U2R59_001626"
     CDS             complement(1112..1801)
                     /locus_tag="U2R59_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8966017.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="U2R59_001627"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="U2R59_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEM8966018.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="U2R59_001628"
     CDS             complement(2328..2831)
                     /locus_tag="U2R59_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEM8966019.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="U2R59_001629"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="U2R59_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEM8966020.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="U2R59_001630"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="U2R59_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEM8966021.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="U2R59_001631"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="U2R59_001631"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEM8966022.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="U2R59_001632"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="U2R59_001632"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEM8966023.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="U2R59_001633"
     CDS             complement(6443..7462)
                     /locus_tag="U2R59_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HEM8966024.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="U2R59_001634"
     CDS             complement(7635..8540)
                     /locus_tag="U2R59_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8966025.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="U2R59_001635"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="U2R59_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEM8966026.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="U2R59_001636"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="U2R59_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEM8966027.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="U2R59_001637"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="U2R59_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEM8966028.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="U2R59_001638"
     CDS             9753..10397
                     /locus_tag="U2R59_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8966029.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="U2R59_001639"
     CDS             complement(10453..10956)
                     /locus_tag="U2R59_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEM8966030.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="U2R59_001640"
     CDS             11553..12518
                     /locus_tag="U2R59_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEM8966031.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="U2R59_001641"
     CDS             complement(12617..13789)
                     /locus_tag="U2R59_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966032.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="U2R59_001642"
     CDS             complement(13776..14921)
                     /locus_tag="U2R59_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966033.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="U2R59_001643"
     CDS             complement(14935..15867)
                     /locus_tag="U2R59_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966034.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="U2R59_001644"
     CDS             15984..17063
                     /locus_tag="U2R59_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEM8966035.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17678
                     /locus_tag="U2R59_001645"
                     /pseudo
     CDS             17060..17678
                     /locus_tag="U2R59_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17788..18015)
                     /locus_tag="U2R59_001646"
     CDS             complement(17788..18015)
                     /locus_tag="U2R59_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8966036.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18118..20706)
                     /locus_tag="U2R59_001647"
     CDS             complement(18118..20706)
                     /locus_tag="U2R59_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEM8966037.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20726..21385)
                     /locus_tag="U2R59_001648"
     CDS             complement(20726..21385)
                     /locus_tag="U2R59_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8966038.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="U2R59_001649"
     CDS             complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="U2R59_001649"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEM8966039.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22158..23024)
                     /locus_tag="U2R59_001650"
     CDS             complement(22158..23024)
                     /locus_tag="U2R59_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8966040.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23133..23774
                     /locus_tag="U2R59_001651"
     CDS             23133..23774
                     /locus_tag="U2R59_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEM8966041.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="U2R59_001652"
     CDS             complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="U2R59_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HEM8966042.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25215..26114)
                     /locus_tag="U2R59_001653"
     CDS             complement(25215..26114)
                     /locus_tag="U2R59_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8966043.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26116..26913)
                     /locus_tag="U2R59_001654"
     CDS             complement(26116..26913)
                     /locus_tag="U2R59_001654"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEM8966044.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26891..27595)
                     /locus_tag="U2R59_001655"
     CDS             complement(26891..27595)
                     /locus_tag="U2R59_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEM8966045.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27726..28301
                     /locus_tag="U2R59_001656"
     CDS             27726..28301
                     /locus_tag="U2R59_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEM8966046.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28419..29096
                     /locus_tag="U2R59_001657"
     CDS             28419..29096
                     /locus_tag="U2R59_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HEM8966047.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6167 c         5230 g         9139 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaatgcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgcgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc
    17221 ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc
    17281 ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg
    17341 tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt
    17401 ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga
    17461 ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca
    17521 tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg
    17581 acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca
    17641 cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac
    17701 ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg
    17761 caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg
    17821 attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga
    17881 ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat
    17941 ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc
    18001 ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga
    18061 aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca
    18121 agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc
    18181 tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc
    18241 tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc
    18301 cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt
    18361 tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga
    18421 atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat
    18481 ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc
    18541 ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa
    18601 attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc
    18661 actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt
    18721 tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc
    18781 agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa
    18841 ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca
    18901 atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa
    18961 cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg
    19021 gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc
    19081 atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc
    19141 ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg
    19201 attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg
    19261 accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat
    19321 cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa
    19381 aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc
    19441 cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc
    19501 tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc
    19561 caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt
    19621 ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc
    19681 ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt
    19741 ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga
    19801 attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg
    19861 ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat
    19921 ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg
    19981 tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg
    20041 aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt
    20101 gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa
    20161 agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg
    20221 attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat
    20281 ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat
    20341 tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat
    20401 tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc
    20461 ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc
    20521 ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc
    20581 tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt
    20641 actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg
    20701 ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta
    20761 aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag
    20821 tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct
    20881 cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa
    20941 gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg
    21001 ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca
    21061 aattcggcag attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag
    21121 tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct
    21181 ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt
    21241 taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca
    21301 aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc
    21361 catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc
    21421 tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag
    21481 ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca
    21541 atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca
    21601 taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat
    21661 cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac
    21721 gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat
    21781 tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct
    21841 cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg
    21901 cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta
    21961 tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt
    22021 gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag
    22081 gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt
    22141 tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat
    22201 aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc
    22261 tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt
    22321 atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg
    22381 gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga
    22441 cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag
    22501 agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat
    22561 gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat
    22621 tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc
    22681 tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc
    22741 gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat
    22801 tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg
    22861 gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc
    22921 aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga
    22981 ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc
    23041 tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct
    23101 agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact
    23161 acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact
    23221 tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg
    23281 gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata
    23341 acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg
    23401 atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag gccttagaac
    23461 tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc
    23521 ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct
    23581 tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat
    23641 tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga
    23701 atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg
    23761 atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca
    23821 aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat
    23881 cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc
    23941 aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat
    24001 tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc
    24061 tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc
    24121 agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac
    24181 agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa
    24241 gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt
    24301 cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac
    24361 tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc
    24421 ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc
    24481 ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc
    24541 ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc
    24601 gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg
    24661 attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta
    24721 catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc
    24781 gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga
    24841 catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc
    24901 attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag
    24961 gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt
    25021 aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg
    25081 cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc
    25141 ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc
    25201 aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa
    25261 ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa
    25321 tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc
    25381 agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc
    25441 tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc
    25501 gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc
    25561 aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat
    25621 tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc
    25681 tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac atggattact
    25741 tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt
    25801 ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt
    25861 tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct
    25921 tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct
    25981 acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt
    26041 gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc
    26101 catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg
    26161 catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg
    26221 gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc
    26281 caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa
    26341 cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat
    26401 cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa
    26461 tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt
    26521 acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc
    26581 atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt
    26641 tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa
    26701 atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa
    26761 cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc
    26821 tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt
    26881 tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt
    26941 tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc
    27001 gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag
    27061 cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat
    27121 aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt
    27181 ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat
    27241 aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca
    27301 tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca
    27361 tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc
    27421 gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa
    27481 tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca
    27541 attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg
    27601 atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta
    27661 ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg
    27721 atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg
    27781 agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt
    27841 atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg
    27901 ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa
    27961 cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt
    28021 caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa
    28081 ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt ttagctattg
    28141 atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat
    28201 ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg
    28261 ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa
    28321 ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag
    28381 tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg
    28441 ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag
    28501 aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt
    28561 tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac
    28621 gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc
    28681 aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg
    28741 acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga
    28801 atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa
    28861 aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct
    28921 gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca
    28981 cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata
    29041 caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct aattaaaaa
//
LOCUS       DASHXG010000032        25503 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.032, whole genome shotgun sequence.
ACCESSION   DASHXG010000032 DASHXG010000000
VERSION     DASHXG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.032"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            134..3661
                     /locus_tag="U2R59_001658"
     CDS             134..3661
                     /locus_tag="U2R59_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HEM8966048.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="U2R59_001659"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="U2R59_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEM8966049.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="U2R59_001660"
     CDS             7449..7790
                     /locus_tag="U2R59_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966050.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="U2R59_001661"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="U2R59_001661"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEM8966051.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /locus_tag="U2R59_001662"
     CDS             9147..11567
                     /locus_tag="U2R59_001662"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEM8966052.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="U2R59_001663"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="U2R59_001663"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEM8966053.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13001..13738
                     /locus_tag="U2R59_001664"
     CDS             13001..13738
                     /locus_tag="U2R59_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8966054.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13752..14567
                     /locus_tag="U2R59_001665"
     CDS             13752..14567
                     /locus_tag="U2R59_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEM8966055.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14580..15227
                     /locus_tag="U2R59_001666"
     CDS             14580..15227
                     /locus_tag="U2R59_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8966056.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15243..15899
                     /locus_tag="U2R59_001667"
     CDS             15243..15899
                     /locus_tag="U2R59_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEM8966057.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16061..16882
                     /gene="racE"
                     /locus_tag="U2R59_001668"
     CDS             16061..16882
                     /gene="racE"
                     /locus_tag="U2R59_001668"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEM8966058.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16885..18240
                     /gene="rph"
                     /locus_tag="U2R59_001669"
     CDS             16885..18240
                     /gene="rph"
                     /locus_tag="U2R59_001669"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HEM8966059.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKEQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18241..18759
                     /locus_tag="U2R59_001670"
     CDS             18241..18759
                     /locus_tag="U2R59_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEM8966060.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18866..19366
                     /locus_tag="U2R59_001671"
     CDS             18866..19366
                     /locus_tag="U2R59_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8966061.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19646..20566)
                     /locus_tag="U2R59_001672"
     CDS             complement(19646..20566)
                     /locus_tag="U2R59_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEM8966062.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20731..21744
                     /locus_tag="U2R59_001673"
     CDS             20731..21744
                     /locus_tag="U2R59_001673"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEM8966063.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21854..22609)
                     /gene="fabI"
                     /locus_tag="U2R59_001674"
     CDS             complement(21854..22609)
                     /gene="fabI"
                     /locus_tag="U2R59_001674"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HEM8966064.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22829..23269
                     /gene="fabZ"
                     /locus_tag="U2R59_001675"
     CDS             22829..23269
                     /gene="fabZ"
                     /locus_tag="U2R59_001675"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEM8966065.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23384..24145)
                     /locus_tag="U2R59_001676"
     CDS             complement(23384..24145)
                     /locus_tag="U2R59_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8966066.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24334..25428
                     /locus_tag="U2R59_001677"
     CDS             24334..25428
                     /locus_tag="U2R59_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8966067.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8446 a         4424 c         5386 g         7247 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcgctgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaacaa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa ccgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataactaa tagattagaa atggaagaaa tatttatggg agaataaacg
    12901 ttctaagaaa ctttacaaat tactaaacta tcagatataa tgtattttat tatacatctt
    12961 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
    13021 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
    13081 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
    13141 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
    13201 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
    13261 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
    13321 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
    13381 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
    13441 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
    13501 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
    13561 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
    13621 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
    13681 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
    13741 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
    13801 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
    13861 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
    13921 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
    13981 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
    14041 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
    14101 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
    14161 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
    14221 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
    14281 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
    14341 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
    14401 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
    14461 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
    14521 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
    14581 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
    14641 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
    14701 aattatcaaa gaataaagta gtgagcgcct tagcaaaggc atatgtagaa ttttttagaa
    14761 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
    14821 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
    14881 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
    14941 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
    15001 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
    15061 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
    15121 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
    15181 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
    15241 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
    15301 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
    15361 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
    15421 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
    15481 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
    15541 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
    15601 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
    15661 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
    15721 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
    15781 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
    15841 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
    15901 agatgattct tttagcggtt gtggcaaact aaagtcacaa ccgcttttcc tctttccatt
    15961 cgaaaaaaag agatttcgat tgttttaagc aagtaagagc acttgaaaat tcacgctaaa
    16021 aagtacacaa tagggaggat agaatttatt gaaaaaaagg atgatacgat tgacagataa
    16081 tcgccctatc ggatttattg attcaggtgt cggcggcttg actgtagtaa aagaagccct
    16141 gaaacaatta ccgaatgaaa atattttatt tgtaggagac acagcacgct gcccatatgg
    16201 ccctagaccc gcggaacagg taatccagta tacttgggaa atgacggatt atctggtgga
    16261 gcaaggaatc aagatgctgg tgatcgcctg caataccgca actgcggtgg ctttagaaga
    16321 aatcaaagct gctctttcta ttccagtcat cggtgtgatc cttcccggta ctagagcggc
    16381 agtaaaaaaa acacaaaata aacaagttgg cattatcggt acgattggta cggtaaaaag
    16441 tcaagcttat gaaaaagcac tgaaagagaa agtaccagaa ttgactgtga caagtcttgc
    16501 ttgtcccaaa tttgtttcag ttgtcgaaag taatgaatac cattcatcgg tggcgaaaaa
    16561 aattgtggca gaaacattag ctcctttaac cactaaaaaa atcgatacat tgattttggg
    16621 atgcacccat tatccattat tacgccccat cattcaaaat gtaatgggag aaaatgttca
    16681 actgatcgat tctggagcag aaacagtagg tgaagtatct atgctgttag attatttcaa
    16741 tttgagcaat tcaccgcaaa atggtcggac attatgccag ttttatacaa ctggctctgc
    16801 caaacttttc gaggaaatag ctgaagactg gcttggaatc ggacacttaa atgtagaaca
    16861 tatcgaattg ggaggaaaat aaggatgcgt catgacggga gaaaagccca agagcttcgc
    16921 aaactggagc ttcaaacaaa tgttttcaaa tatccagaag gatcggtagt gatccgtttt
    16981 ggtgatacaa cagttatttg ttctgcaaca atagaaaatt ctgttccccc ttttttgaga
    17041 gaaacaggaa caggatgggt gacagcagaa tatagtatgc tgcctcgagc aacgagtacg
    17101 agaaatcgta gagaaagcag caaagggaaa ctttctggta gaacaatgga aatccagcgt
    17161 cttattggtc gttccttgcg tgcagtagta gacttggaaa aattaggaga acgtagtatc
    17221 atcgtagact gcgatgtgat ccaagcggat ggcggtacta gaacagcaag tatcactggg
    17281 gcatttgtgg cattgaaatt agccattgaa aaacttttaa gagaaaaaga attgtcagaa
    17341 gatccaataa aagaacatct tgctgcagtt agcgtaggaa tcttaccaga tgggacttgc
    17401 gtcacagatt tggattacca agaagattcc gcagcacttg tagacatgaa tcttgtaatg
    17461 acagaatctg gaaaattcgt ggagattcaa ggaactggag aagaagcaac gtttgatggt
    17521 gaacagttga atgaaatgct cttttttgga aaaaacgcga ttgaagattt gatcaaagag
    17581 caaaaacatg ctttgctaac agagtttgct caaaatgatg agcggataga agaaacaaaa
    17641 acaatcatca ttgcgacaag aaatccagga aaagcagaag agtttcgaaa tatgttcaaa
    17701 gaagcgggat atcatgtaaa aacattactt gactatcctg aattgccaga tgtggaagaa
    17761 actggcagca catttgaaga aaatgcccga ttaaaagcag aaacgattgc acaattgctt
    17821 gatcagccag tcttagcaga tgattcaggt ttgaaagtgg atgctttagg cggtatgcca
    17881 ggaatctatt ctgcacgttt tgcaggggaa caaaaaagtg atgcggggaa taacgccaaa
    17941 ttattatatg aattgacaga tgtgccggat gaaaaaagaa cagcacaatt ccattgtacg
    18001 ttagtattcg cggcacccaa aaaagacagc cttgtagtag aagcggaatg gcccggtcga
    18061 gtagcccgta taccatctgg cgaaaatggc tttgggtatg atcctttatt tatcccagaa
    18121 ggtaaggaac aaacagcagc agaattatcg agcgaagaaa aaaacaagat cagtcatcgg
    18181 gctcaagcaa tgaaaaaatt gagtgccgag tggaaacaat ggctggaagg agagagatag
    18241 atgcggtatt tagtagtaag tgataatcat ggagacagag atatcctcgt tgacttagta
    18301 gatcgttatc gttctgaagt ggatatcttt ttccattgtg gtgattcgga attagaagct
    18361 tctgacccat tatgggatac attccaagtg gttcaaggta attgtgatta tggaccagga
    18421 ttcgaacaga aaaaagtgat ccaaactggt caggatacag tattcatgac tcacggtcat
    18481 ttatcgaatg tccgatttgg tttgacacag ttagcaatcg aagctcgagc tgcaactgcc
    18541 gatatggtgt tttttggtca tacccatcaa ataggctgtg agatggatca gaaaatcctg
    18601 tttttgaatc ctggtagcat ttctcagcct agaggcccga tccaaatccc atcatatgct
    18661 cttatcgaaa gtttagatga ccaaatttct gttcaatact ataaccgtgc ccatcaggca
    18721 gttgaagagt tggccttttc tttttcgaga gagcgctgaa taaaaaaact ctaattttta
    18781 ataaaaataa gctttatttt atgaattttg catccggttt cggtaaaata gtagtgttga
    18841 atgaaataga aatggaggcc atcagatgat tggacctata gtaagagaaa tgctgctgga
    18901 aaatcaggaa acgtttttga ttcctgcaga aaatgtggca aatgttatgt atcatcatcc
    18961 attgtcccat ggtttacttg tgttatcgaa ggtcggttat tccaaaattc ctgtattagg
    19021 aaaagatgat cactttgtag gactagtaag tttatcagat gtggtcaata aaatgattga
    19081 cttgcaaaca atcagcatgg acccgttaga aggactaacg gttgctgatg tgacagaaac
    19141 agatgttccg acaattgatg aaaattggga actagaagaa gtactccatt tgttagtcga
    19201 ttcgcctttt ttaccggttg tcacagaaga tcggattttc aaaggaatca ttacaagaaa
    19261 agagctgctt aaagccgtaa acttcatggt gcatgaatta gaacgtcgta atatattgtc
    19321 tccgaaaatc gaagaattaa aagaacaaat cgatatcgtg agctaaagaa cgagaaacta
    19381 aaagataatc aaaaaataag tagaaaaaac agcgtaccag ttttgacttt atcttgaaaa
    19441 agaggctggg acaaaagcgt ttaactccaa gaaataagaa ggaattcacg aaaattgctt
    19501 ttcaaatttt tgtgaatttc agcttatttc cgaaggagtt gcttctgctt ccgccgttta
    19561 tacgtgttta gagcgtggga caaaagtgtt ctttactttt gtcccacgct ctttttagtg
    19621 agattcgttg catcgtttgt ccaaattatt ttccgacagc aattggactg ttcggaatcg
    19681 tgaaaccaga agctgtcaat tctttgacat aggagctcaa gaactcttct tttaaggcat
    19741 attgttttcc gttcaatgcg tagcagaccg tacgaatcgc aaaattgctg tttccaagat
    19801 ccactaatcc aaagatagaa ggttcagttt ggagctcttc ttggtatttt tcagctaatg
    19861 tacgatttac tcgatcaatg atctcataga ttttgtcata tccttcttca ggaacaatcc
    19921 gaatatctaa aagtacttgc atatttgcac gagagagatt gctgatcgtg gtgatgtttc
    19981 gattcgggat gaaatggaca gtaccatccg ttgctttcag ctgaagggta cggataccaa
    20041 cagatacgac ggttccttca atcgttaagt ttgctagctt gatgtagtcc ccaacatcca
    20101 tctgttgttc catgataata aaaaatccgg taataacatc actcatgaac ccttgggcac
    20161 caagaccgat tgccacacct gcaattccgg caccagccaa aagtgatccg atcggcacac
    20221 cgatagcaga taaaattgca tagataaaaa agaaaccaag ggtataatga aaaatagtat
    20281 ttaaaagact atgtaaagtc tttaagcggc tctcgtttag aatggctttt ttagaatact
    20341 gattaaaaga cttatcaatc agatattttc ccacacggtg aagaatccaa aaaaggacga
    20401 tcaaaaaaat cagatataaa cttttttgga taaaggcagc caaaatggcg tcccaatcaa
    20461 tcccgtccca aaaccgctga aacgcattta ctttgctgac agcttgatct gtcaatgtct
    20521 cgccagaaga gtctgtcgta ccggcagttg ctaataatga aaacataaaa tcctcttttc
    20581 taaaatttga ttctttctgt attgtaccaa gaagttttca aaaaaggaaa tagcaaaaat
    20641 aactataatg aaggaaaaaa gctgaaaata aaatgacaaa taatatggat aatgataaaa
    20701 tgtggagaaa ataacgaagg tggtaagtat atgcaaatcg attggaacaa tctaggtttt
    20761 tcttatatca aaactccttg gcgttttatt gccaaatgga aagacggaca atgggaagaa
    20821 ggagaattga cagaagataa ttacctgacg attcatgaag gctctccagc gcttcattat
    20881 ggtcagcaat gttttgaagg tctaaaagct tatcgtcgaa aagacggcaa ggtcaatctc
    20941 tttcgacctg aacaaaatag tcgacggatg aatcaaagtg ctagacgatt gctgatgcca
    21001 atggtccctg aaaagatgtt cgttgatgct gtcaagcaag tggtaaaagc aaatgaagat
    21061 tttgtgccgc cctatggaac aggcgctaca ttatacttgc gccctttact gattggggtc
    21121 ggtgaaaaca ttggtgtcca tccagctcca gaatatttat ttgtcgtctt ctgtacgcca
    21181 gtaggagcgt atttcaaagg tggactaaaa ccaacgaatt ttattgtatc tgattacgat
    21241 cgtgctgctc ctaaggggac tggtgcagca aaagtcggcg gaaattacgc agcgagttta
    21301 cttccaggaa cagaagcaaa agaactggat tactcagatt gtgtttatct tgatccagcc
    21361 acacatacga aaatcgaaga agtaggtgca gcaaatttct ttggaattac aaaagacgga
    21421 aaattcatca ctccgcaatc gccctctatc ttaccaagta tcacgaaata ttccttgttg
    21481 cagttagctg aagaacgact aggactgcaa gcaattgaag gagatatttt cattgatgat
    21541 ctagatcaat ttgcagaagc tggtgcatgt ggtacagcgg ctgttatttc tccaatcggt
    21601 gggatttatc acaataacaa tcttcatgta ttttatagtg aaacggaagt aggaccagta
    21661 acaaaacggt tgtatgatga attgacaggt attcaatttg gagacataga agcaccagaa
    21721 ggctggattg aagtcgtgga ataatttcaa agtaatgagt tgaaaaaaac gtaaaaagaa
    21781 aaaatcagga agagacttta aaaagttttt tcctgatttt tatatgtttt actttaaaga
    21841 atgcaacaaa agtttatgaa agatggacac ctttgtcaac gtagataata tcaccgatga
    21901 ttccgctgga aagtgggctg attaagaaag cacaagcatt accgacttct tcgatcgtca
    21961 caccttgctg atcaggcgta cgagattcag ataactggat cagtttttga tagtctttaa
    22021 cacctgtgac agctaatgtt ttgattgccc cagctgagat tccattgacc cgaattcctt
    22081 taggcgagaa ctcagctgcc aaataacgga tagcagcttc aagagaagct ttcgcaatac
    22141 ccatcatgtt ataattcggg attgcgcgtt ctgaacctag ataagtcatg ctaacgatcc
    22201 cgctgtttgg tgcaagaaac ggttgtgcgt attttgatac agcaattaaa gagtagctgc
    22261 tgatatcttg agctaattga tagccgtctc tggaaatatc agacacattt ccggacaatt
    22321 cttctttgtt ggcgtaagca actgcatgga caaggccgtg gatctcccca gcatattcac
    22381 cgatggcatt cattgctttt tcgatgcttt cgtcgctaga aacatcacat tctacagtga
    22441 atgcttcttc gccgaccaat ttgactaatg attttttcat tcgttcattt tggtaagtat
    22501 agataatttc tgccccttgt ttcaacattg cttcagcaca accccaagca atgctttttt
    22561 tgttagcgac gcccataatg acgatttttt ttccttctag aaatgacata atgactctcc
    22621 tttgtttctg ataaaaattt gatagtcgta aaaaaataga gaataatagc taaaataact
    22681 tcttgatttc ttaattatta gtcaaaatgt tttgattgtc aaactatttt ttcttaaatt
    22741 aaaaaaagat tgctaaatat ttaggaatat gatactttga tagtcaaagt aatgaaaatg
    22801 gcaattgcct gaaagaagga gtttaattat gtcttacgta ttatctgcta ctgaagtaat
    22861 ggaattgatt cctaatcgtt atcctatttg ttatattgat tatgtagata ctttagaacc
    22921 aggaaaaaag atcgttgcga caaaaaatgt aacaatcaat gaagattttt tccaaggtca
    22981 ctttcctgac aatccagtga tgccgggtgc gttgattcta gaaacactgg cacaagcagg
    23041 ttcgatactt atcctaaaat cagaagagtt tctaggaaaa agagcttata tcggtgggat
    23101 caataaggcc aaattccgtc aaaaagttgt tccaggagat gtgctgaaat gtcattttga
    23161 aatcaccaaa atgaagggat cagtcggtac agcgttatct gcagcatatg tagatgataa
    23221 aaaagtctgt gagtgcgagt tcacgttcat cgtcaaccaa aatgcttgac tataaaacct
    23281 gatatagcaa aacaaaagga agcttacttg ctttttatgt aaaaagaaga cgcctgaatc
    23341 ctagcatacg ttgtcatcta tgcaggattc agacgttatt tttttatttt tgttttgctt
    23401 cttgcagtat attgatttta tcgattttta cttcttcttt tggtttgtct gaactatctg
    23461 tttcgatatt tgcaatagca tccacgacat ccattccttc aatcacttgg ccgaagacag
    23521 tataatggcc atctagtgaa ggataaccgc cgtttttata agcgtcgatg attgcttgag
    23581 gatagtcgtc ttttaaaaga ccatcatgca tatcatctgt attttgaacg ataaagaact
    23641 ggctgccgtt actgttagga tcttgtgagc gagccataga taacgcacct cttatattat
    23701 aaaggtggtt gttgatctct gtttcaaatc cttctcccca aatgctttcc cctccagtgc
    23761 catcgccttt aggatcgcca ccttggatca tgaaatcttt gatgacgcga tggaaagtca
    23821 gtccgttgta gtaaccgtct tttgcatgtg tcataaagtt ttcaaccgct tttggtgcgt
    23881 gttcgggaaa taatttgatt ttgattgtgc ctttattcgt caccatttcg accagatctt
    23941 cattttcggc gacatctttc gtcaattgtg gtaattccaa tgcgttcaaa tcgacgctac
    24001 tggcagtcgt gctttccgca gtagatgtac tttttgaact ttctgtagac gaactagaag
    24061 aagtcgtgtt gtttgcagaa caaccagcag caaacagcaa tgctgctgct aaactaatac
    24121 ttaaaataac tttatttttc ttcataactg ttcctttcca atttactatt ttgttatctt
    24181 taatgataac aaaatagagg gaaaatacct acttaaatta ttggaattta tcatttattt
    24241 taaaagaaaa agaaaaggtg tagaccattt actttgtgtt tgctataatg taagtggata
    24301 caaaaacgaa aagatgcagg aggaaatggt aatatgggaa aattaggaat ctcgatttat
    24361 ccagaacggt caacatttga aaaggacaaa gcgtacttgg atttagctca taagtatggg
    24421 tataaacggg tttttaccag tttgctgcag atcaatgatg ataaagaaaa agttctttca
    24481 gaatttaaag aagtagttga ttacgcgaat agcctaggca tggaagtaat ggttgatatc
    24541 aatccagcgt tatttgaaca gttggagatt tcttacgatg acttatcttt tttccataag
    24601 atgggtgcct acggggtccg cttagatatc ggattcacag gagcagaaga agcaaaaatg
    24661 acgcgcaatc cttttggtat caaaatcgag atcaatatga gttcgggcac gaattacgtt
    24721 gacaacatca tgagttattc gccaaacacg gataatttat taggttctca taatttttat
    24781 cctcatcgat actctggttt aggatacgaa cactttgttt tttgttcaga aaaattcaga
    24841 aaatataatt tgaatacgat ggcattcgtc aattcgcaat ctgctgagtt tggcccttgg
    24901 cctacgcaag atggcttgtg cacgctggaa gaccaccgag atcttgaaat tgcgacacaa
    24961 gtgaagcatt taatccttac aggattgatt gatgatattt ctattggaaa tgcgtacgca
    25021 agtgaagaag aattgaaaga aatggcagaa gcatttaacg cggattatcc aacattgaaa
    25081 gtagatacgg aagaaggtat tacagaaaac gaacgaatct gcttgtttga taaccttcat
    25141 agttatcgag gggatcgctc agaatatatc cttcgttcaa cgatgactcg tgtatactac
    25201 aaagataaag atttcccgcc tcataatacg cgagatatgc atcatgggga tgtactgatt
    25261 gacaatgaag ggtacggtca atacaaagga gaaacacaaa tcgccttgaa ggatatgaaa
    25321 aacgacggac gtgtcaatgt tgtaggaaga atctccgatg acgaattatt cctccttgac
    25381 tttttgaaac catggtcaag ctttaaatta attgaaaata aaaaatagat aattagttat
    25441 tgcagaaata atccgctaga aatagccagt tatttctgct tttttatttt gtttttttat
    25501 agg
//
LOCUS       DASHXG010000033        24503 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.033, whole genome shotgun sequence.
ACCESSION   DASHXG010000033 DASHXG010000000
VERSION     DASHXG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.033"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(26..601)
                     /locus_tag="U2R59_001678"
     CDS             complement(26..601)
                     /locus_tag="U2R59_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8966068.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(606..1580)
                     /locus_tag="U2R59_001679"
     CDS             complement(606..1580)
                     /locus_tag="U2R59_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HEM8966069.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1604..1648)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1863..2831
                     /locus_tag="U2R59_001680"
     CDS             1863..2831
                     /locus_tag="U2R59_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8966070.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2928..3221
                     /locus_tag="U2R59_001681"
     CDS             2928..3221
                     /locus_tag="U2R59_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEM8966071.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3339..3575
                     /gene="secG"
                     /locus_tag="U2R59_001682"
     CDS             3339..3575
                     /gene="secG"
                     /locus_tag="U2R59_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEM8966072.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3678..4433
                     /locus_tag="U2R59_001683"
     CDS             3678..4433
                     /locus_tag="U2R59_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEM8966073.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4436..6793
                     /gene="rnr"
                     /locus_tag="U2R59_001684"
     CDS             4436..6793
                     /gene="rnr"
                     /locus_tag="U2R59_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEM8966074.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6815..7279
                     /gene="smpB"
                     /locus_tag="U2R59_001685"
     CDS             6815..7279
                     /gene="smpB"
                     /locus_tag="U2R59_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEM8966075.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7581..8300
                     /gene="atpB"
                     /locus_tag="U2R59_001686"
     CDS             7581..8300
                     /gene="atpB"
                     /locus_tag="U2R59_001686"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEM8966076.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8353..8568
                     /gene="atpE"
                     /locus_tag="U2R59_001687"
     CDS             8353..8568
                     /gene="atpE"
                     /locus_tag="U2R59_001687"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HEM8966077.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8659..9183
                     /gene="atpF"
                     /locus_tag="U2R59_001688"
     CDS             8659..9183
                     /gene="atpF"
                     /locus_tag="U2R59_001688"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEM8966078.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9170..9712
                     /locus_tag="U2R59_001689"
     CDS             9170..9712
                     /locus_tag="U2R59_001689"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEM8966079.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9735..11291
                     /locus_tag="U2R59_001690"
     CDS             9735..11291
                     /locus_tag="U2R59_001690"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEM8966080.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11305..12207
                     /locus_tag="U2R59_001691"
     CDS             11305..12207
                     /locus_tag="U2R59_001691"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEM8966081.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12230..13636
                     /gene="atpD"
                     /locus_tag="U2R59_001692"
     CDS             12230..13636
                     /gene="atpD"
                     /locus_tag="U2R59_001692"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEM8966082.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13650..14072
                     /locus_tag="U2R59_001693"
     CDS             13650..14072
                     /locus_tag="U2R59_001693"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEM8966083.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14541..14771
                     /locus_tag="U2R59_001694"
     CDS             14541..14771
                     /locus_tag="U2R59_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEM8966084.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14868..16169
                     /gene="murA"
                     /locus_tag="U2R59_001695"
     CDS             14868..16169
                     /gene="murA"
                     /locus_tag="U2R59_001695"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEM8966085.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16182..16358
                     /locus_tag="U2R59_001696"
     CDS             16182..16358
                     /locus_tag="U2R59_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEM8966086.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16493..16789
                     /gene="yidD"
                     /locus_tag="U2R59_001697"
     CDS             16493..16789
                     /gene="yidD"
                     /locus_tag="U2R59_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEM8966087.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16853..17320
                     /locus_tag="U2R59_001698"
     CDS             16853..17320
                     /locus_tag="U2R59_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966088.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17405..18289
                     /locus_tag="U2R59_001699"
     CDS             17405..18289
                     /locus_tag="U2R59_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8966089.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18403..18639
                     /locus_tag="U2R59_001700"
     CDS             18403..18639
                     /locus_tag="U2R59_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEM8966090.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18727..18807
                     /locus_tag="U2R59_001701"
     tRNA            18727..18807
                     /locus_tag="U2R59_001701"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18761..18763,aa:Tyr,seq:gta)
     gene            18814..18885
                     /locus_tag="U2R59_001702"
     tRNA            18814..18885
                     /locus_tag="U2R59_001702"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18846..18848,aa:Gln,seq:ttg)
     gene            19011..19181
                     /locus_tag="U2R59_001703"
     CDS             19011..19181
                     /locus_tag="U2R59_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966091.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19401..20108
                     /locus_tag="U2R59_001704"
     CDS             19401..20108
                     /locus_tag="U2R59_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966092.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20167..20811)
                     /locus_tag="U2R59_001705"
     CDS             complement(20167..20811)
                     /locus_tag="U2R59_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEM8966093.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20938..21225
                     /locus_tag="U2R59_001706"
     CDS             20938..21225
                     /locus_tag="U2R59_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966094.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21333..21653
                     /locus_tag="U2R59_001707"
     CDS             21333..21653
                     /locus_tag="U2R59_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8966095.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21971..23047
                     /locus_tag="U2R59_001708"
     CDS             21971..23047
                     /locus_tag="U2R59_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEM8966096.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRPNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23044..23763
                     /locus_tag="U2R59_001709"
     CDS             23044..23763
                     /locus_tag="U2R59_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEM8966097.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            23891..24442
                     /gene="raiA"
                     /locus_tag="U2R59_001710"
     CDS             23891..24442
                     /gene="raiA"
                     /locus_tag="U2R59_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEM8966098.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         8120 a         4277 c         5269 g         6837 t
ORIGIN      
        1 attttgctaa tccagctctg tttattcagc ctatttttct ttttgaatat atcaagcgtt
       61 gtggcaacat agtgatgact aatgaaacaa cgacgataga caacaaacga tcaaggtagt
      121 ctgtacctgc ctgtaccaag atcacacttg ttgtctgact taaacctaac ccatgtaata
      181 gctgaacgat catactggat cctgaggagg tgatcccgcc aaataactga acggtaatga
      241 tcgaagaaac gatcgttcca ggtaccgaca aaatcaaagc gagtaataac agtttcaagc
      301 tgtttttatc tttgccgaga tatcttggca aaatcaatcc agcaagcaag cctgtgagaa
      361 tttggattgg cgaataatac agagaaaaaa tatctgtagt cactccactt aaaataccgc
      421 tggacaatcc tgtcagcatt ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc
      481 cgatagaatc gagatagatt ggcaaacgaa gccataaagc aatcgttcct ccaatataat
      541 tgatcccaat acacaaagcc atcactgtaa gtacgcgagt tgccattttg tttttattca
      601 ttttgttagc ccatctttaa cctttccaaa tctttcataa tcgtttcttc ttgtgcattt
      661 aaaagaacgg ttaaaaactt tcggaaaaaa agacgagtat ctacttttgt cataatttta
      721 ctgttagcag gtttctgcca aaattcataa cgatcaacca atgtttgtcc acgacttatt
      781 ccttgagttt ccacagcagt gaagcttttg aaaccttcac agatggcctc ctcgataaaa
      841 taagcaacag ctaacggatc attgatgaca catcctaaaa ttctttcttg tttccagtgg
      901 aagtcaaaat aaaaacgagt gatcgctttt agatactctc cctcttcagg attcatttga
      961 cagcagtatt cgaggatagt cggtgtcaag acgatttctc ttgtcacatc taacccaacc
     1021 atttctatcg tttgtttgag attctcgaat acataagaag ctgcttcagg atcacaccag
     1081 taattgtatt cagcaactgg cgaacagtta ccatggcttt tgtaagttcc acccatcgag
     1141 acaaaacgtt ccatatgttt cccaatattt gggttgactt tcaaagcaga agcgatattg
     1201 gtcaaaggac ccaaagcaat gactgatgta tttgtctttt ctttgaaata atcagccaaa
     1261 aaatcaacgg catggagagg ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc
     1321 cctaaaccat ccataccatg agtgtcttgt gcactgatga aaggttgctt caaaggtttt
     1381 tccattcctt gataaacagg aatgtctaaa cgatcacagc gttccaggca tttcagcaca
     1441 ttctgcgtac ctatatctgc agggacattc ccacaaacta cggtaatagc aactacttcg
     1501 atatcagggg atttgacagc taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa
     1561 tcaataatta cttttcgcat tatttccaat ctcctttctt tagagatact tagtttttta
     1621 ttctgggaag tttccgaacc agtccaagac gagcgtcttg attataatgc acgaaattag
     1681 tatactggct tttattgcga atgtaaatgc tctcttacaa gtaaatctat tgaggagaac
     1741 tttaagtaaa tgatacaatg aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc
     1801 ctatggatcg gtacattgga taatagatag attatagttt ggcagaaagc ggcgggtgta
     1861 caatggttat tttttatttc attcttattc tgataattat agggatcagt taccattttc
     1921 tttcttattt ttatgcaaag aaattagtaa gagcgggagt acagagagga tatgactggt
     1981 atgaagacac tggtcatcgt ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac
     2041 gacaaaaatt agaagaagag tgtgaaagct tttgggagca gggaacaccc aaaacaatca
     2101 aaagttatga cgggttgaaa ctagctggtc agatgttcat ccatccaaat aagcagaata
     2161 aatgggtcat ttgcgtacat gattaccgaa gcacagggaa aagagacatg tctcatatag
     2221 gtaaaagata tgcagagaaa ggattcaacg ttcttgtacc tgatttacgt gcgcacggag
     2281 aaagtgaagg agaaatcatc ggaatgggat ggctagatcg gctagattta attgcctgga
     2341 tccaactcat cttagatgaa cagccgaatg cgtccattat tttacacggc ggatcaatgg
     2401 gagcttctac gatcatgatg gcaagtggtg aaaaacttcc atcagcggtc aaaggattta
     2461 ttttagacag cggatatgtt tctgtttatg cagaattccg atatatgtta agtaaaatca
     2521 ctgtctttcc taaaaaaatg gtcatgagat atgcgaatca ttatgcccag aaatacgccg
     2581 gttactcctt aaagcaagca tcagctacga gacagcttgg cagcaatcat ctgcctttat
     2641 tagtcatcca tggtgaaaga gatcattttg tccctacaga agcagcgtac acgattcaaa
     2701 atgctacggc aggggataaa gcactgctgc ttgttccgga agcagaacac ttggaagcat
     2761 cgatgaaaga tccgaaaacc tattggacag tgattttttc atttattgaa caaagaataa
     2821 cgatgaatta attttctctt cttttttgta agtaattcga ggataaataa ttgtttatag
     2881 atcaggagac tgctaaaata aggtaggaat aaaaaaatat cagttatttg aggagtgcgg
     2941 catatggaaa tcaaagaaga aaaaatcgtc ttgctttatt caatgatgaa caacaagaga
     3001 tcggagaaat gacatggtca gatgcgggcc cagacatcat gatcgttgac catacatttg
     3061 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
     3121 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
     3181 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     3241 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     3301 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     3361 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     3421 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     3481 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     3541 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     3601 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     3661 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     3721 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     3781 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     3841 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     3901 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     3961 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     4021 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     4081 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     4141 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     4201 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     4261 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     4321 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     4381 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     4441 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     4501 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     4561 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     4621 agtgaaactt cctttaaaac caatcctgat cgaaggaaca tttcgagcaa atgaacgagg
     4681 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     4741 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     4801 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     4861 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     4921 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     4981 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     5041 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     5101 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     5161 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     5221 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     5281 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     5341 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     5401 tgtatatttg actgatcgag taattccgat gatcccgcaa cgtttatcga atggtatctg
     5461 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     5521 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     5581 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     5641 tcagctcgta cctatgttcc aagaaatggg tgaattgcac cgaatccttg aaacgatgcg
     5701 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     5761 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     5821 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     5881 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     5941 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     6001 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     6061 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     6121 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     6181 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     6241 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     6301 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     6361 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     6421 gggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     6481 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacagaaag tgcgagtaaa
     6541 agtagtcaaa gctgatccag atgaacgagc agtagatttt gaacttgttt ccgcagaaga
     6601 ggttacagcg ttggaacggc caaaaacacg aaatggaaaa tcaggaaaac gcgaaggaaa
     6661 acaagcagga aaacgcccag aaagaaatgg caagaagaac aaacgatata gcgatagtaa
     6721 gcaaacgttc ggtaagaaaa aagggaagaa gccattttac aaaggtgtta aaaagaagaa
     6781 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaattaat
     6841 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     6901 ggtcttgcaa ggaaccgaga tcaagtcgat acgaaacagc cggatcaatc taaaagatgg
     6961 atttattcgc gtccgcaacg gagaagcttt cttgcataat gttcatatca gtccttatga
     7021 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaaaaa
     7081 acaaatcatc cggcttgaaa atgaattgaa aaatactgga atcactgttg ttcctttaaa
     7141 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcgaaag ggaaaaaatc
     7201 ttatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     7261 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     7321 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcat aggttttttc
     7381 ttagatcagg agcaccgtgt ataaagaaaa attcgcttcg tttttgactg aaataaaaaa
     7441 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     7501 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     7561 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gttccacatt ggaccaattt
     7621 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     7681 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     7741 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     7801 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacatcggtt
     7861 tagtaacaaa aatcgtttta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     7921 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     7981 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     8041 ttccgatgaa actgattgaa gaatttacaa acttattaac acttgcttta cgtctttatg
     8101 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     8161 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     8221 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     8281 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     8341 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     8401 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     8461 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     8521 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     8581 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     8641 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     8701 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     8761 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     8821 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     8881 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     8941 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     9001 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     9061 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     9121 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     9181 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     9241 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     9301 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     9361 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     9421 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     9481 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     9541 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     9601 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     9661 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     9721 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     9781 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     9841 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     9901 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     9961 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
    10021 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
    10081 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
    10141 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
    10201 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
    10261 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
    10321 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
    10381 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
    10441 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
    10501 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
    10561 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
    10621 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
    10681 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
    10741 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
    10801 cggttgatgc cggactatct gtatctcgtg taggaggttc tgcgcaaatc aaagcaatga
    10861 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
    10921 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
    10981 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
    11041 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
    11101 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
    11161 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
    11221 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
    11281 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
    11341 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
    11401 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
    11461 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
    11521 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
    11581 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
    11641 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
    11701 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
    11761 tctgatcagc caagctttga tgaagtccgc aaaattgtaa atatggcaac aactatgttc
    11821 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
    11881 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
    11941 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
    12001 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
    12061 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
    12121 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
    12181 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    12241 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    12301 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    12361 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    12421 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    12481 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    12541 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    12601 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    12661 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    12721 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    12781 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    12841 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    12901 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    12961 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    13021 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    13081 attgcaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    13141 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    13201 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    13261 ggcttcttct tcaagtgctt tagcacctga aatcgtggga gaagaacatt ataaagtagc
    13321 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    13381 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    13441 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    13501 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    13561 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    13621 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    13681 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    13741 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    13801 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    13861 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    13921 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    13981 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    14041 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    14101 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    14161 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    14221 tggaacaccg tatatcagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca
    14281 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    14341 tgaacaccgt ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt
    14401 tgcatatttt tagcatttat ttcctaaaaa atgtaagggg attcctatat ttttaagtat
    14461 acttgttttt ccttttatac attttatggt attatcattt tattagttat tataaaacaa
    14521 tcgttagaaa ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga
    14581 gtcatttggc gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt
    14641 ttttcagacc aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt
    14701 tagggtacac tgcaagtaat tttttcttag aggttatcgc tttatgccga aatcttttcg
    14761 ttagcctgta aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa
    14821 gattttgagt aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca
    14881 tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg
    14941 ttttgcctat tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg
    15001 ttccgattct ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg
    15061 tagattttga tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg
    15121 aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac
    15181 ttgccagaaa tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac
    15241 caatcgattt gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg
    15301 gctatatcga agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta
    15361 gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca
    15421 ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg
    15481 gcgctcaagt ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac
    15541 atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg
    15601 ctgcaatgac acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat
    15661 tgatttctaa attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg
    15721 tcatcggacc aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc
    15781 ctacagatat gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtgg
    15841 tgactgaaac agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg
    15901 ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg
    15961 cagaagtata tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag
    16021 caaatggaat cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc
    16081 atatcaaact acagcaatta ggtgcagacg tcgaacgtgt agacatggat caaacttctg
    16141 ctgaaaaaac agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata
    16201 tcttattaac tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg
    16261 ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc
    16321 caagtttgtg gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc
    16381 tagtcgatat gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt
    16441 gacgttagtc gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa
    16501 gatattgatt tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag
    16561 ctgccgttat tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc
    16621 gctaaaaggg acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg
    16681 cggtatcgat tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga
    16741 accagattat aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg
    16801 aaatttattg tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga
    16861 agaactaaac aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga
    16921 aaaagttcaa gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac
    16981 aataggtgta ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt
    17041 aaccccaacg tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa
    17101 gctttcacag ctagcttcaa accaaactcg gatcattata cgtactggca ctactagtag
    17161 cgctgcgtta cacctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta
    17221 ttttatccat cattactctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt
    17281 gattttagca attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa
    17341 atgctttcaa atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat
    17401 ttttatggga atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga
    17461 tggcaaagag attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa
    17521 aacgcaatta tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg
    17581 aatcagctct cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat
    17641 tccttatatt catggattta atattttccg agatttggaa actctgtttc aactcccagt
    17701 aacgattgaa aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg
    17761 tgattatcaa gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac
    17821 gaaaggacaa ataaataaag gggcacatct ttacggtgga gaatttgggt tgatgttctt
    17881 agatggcgat aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg
    17941 tgaacgcaaa ggtctcgata aaaatgctta taccggaaaa gatgtctttg aattagcaga
    18001 aactggagat gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg
    18061 attattcagt attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggggtttc
    18121 tgcaaaagaa gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt
    18181 cgatctgcat gatttcgaac cgcagatttt attatgtgag tacagaaacg atgctaatct
    18241 tataggtgca gcagcaaact atctcgctgt acgtcaagga gagaattaag agctttagag
    18301 aaggtgcagc ttgcataaaa gaagagaatg aaatgaatag gagattttta cctaaggaat
    18361 gttttatttg ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat
    18421 aaagatattg aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa
    18481 gtcactcagt tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa
    18541 gaatatgaaa ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg
    18601 atagaaacag tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc
    18661 aataaagggt tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa
    18721 cctttcggag gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt
    18781 tcagtggttc gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag
    18841 ggactttgac tccctcatgc gttggttcga atccagctac cccagtatac cacaatcgta
    18901 agctctcgtt agttcgagag ctcttttttt ttgctttgct accttgttcc ttgaagattc
    18961 tgctgaatta agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga
    19021 aagaaaaagt agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca
    19081 atattgaagt gaatattccg aaaaaaggcg gaaaagcggt ccaggtaaaa tcaaaacgcc
    19141 caacgaatca tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata
    19201 agtcggcatt ttcatcgatt ttagggtctt ttgttatttt ctaggttgaa catatctaaa
    19261 aaattgtttc tgacaatagg agtagggaga acgatgtgtg tctaaatcct ctgttgatgg
    19321 atagaaacct ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa
    19381 cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc
    19441 aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa
    19501 gagaattagc agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact
    19561 tggcagatga aggaatctta gaaagaaaga tcggttcggg tacgtatgtt gcgcgagaaa
    19621 aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc
    19681 gagtaccgtc tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg
    19741 aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag
    19801 atgatgtccc tatttgtttt gaagttgcca gtgttccaca aaagctgatc gatggctaca
    19861 gcaaagcaga gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga
    19921 tcggtccagc gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt
    19981 tagaggtaaa acgaagagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg
    20041 gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg
    20101 aaaaataaaa aacaggtgat ccctgattcc ttattagaaa taaaagagaa tcagaatcac
    20161 ctgtttttat atatgatcag ttatcagttg ctcgtgataa gaaacagaac cctcttcaaa
    20221 ttggacttgt ccgttcagca gctcaatgat ggattcttta aagtggttag cacttttttc
    20281 atctacagca cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg
    20341 ttggagttca agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat
    20401 ctcctgttgc aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg
    20461 agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac
    20521 tactgcagct acattgatca gttgattttt tttgaggact tccaacatcg gtacgcccgc
    20581 cgttccactt ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat
    20641 gaaggcgctg cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaatt
    20701 ttttgcttgg tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat
    20761 ctcaatctca ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc
    20821 tctttttttc attttcttta ttcagtataa ataaagttct aggttgtttc aacactgtaa
    20881 cggttgcgca attgctgtag tatgcgataa taaagacaaa ggcaggtgga tctggggatg
    20941 caggaacgaa tgaaaaagta cgatgcaatt acgcattatt tgaagaacaa tggcggctct
    21001 caagtaacgt tgacctttac ccaatttgac gaactgctgt ttcccagtaa cggacttccc
    21061 aaaacagcaa gggaaagtac agattggtgg gcaaatgatt ataaacaccc tgaaaaaggt
    21121 gcctatggct ggataaatgc aggctatgaa gtagttgtca tcaatttgga caaagaatat
    21181 gtcgtgttca ataaattagt gaaatctagt tggctatttg attaaataaa ccgcgtttag
    21241 aaaacgttga caaatttctt tctttttata taataaagta acagacgcga agaaaacgtt
    21301 tgcgtagttt gttttaaaaa ggagagaaaa atatggctaa aaaaacaatc atgcttgtat
    21361 gttcggctgg tatgagcaca agtttactag taacaaaaat gcaaaaagct gctgaagcaa
    21421 aaggaatcga ctctgatatt ttcgctgtgt ccgcttctga cgcagataac aatcttgcaa
    21481 ataaagacgt ggatgtgttg ttattaggcc cacaagttcg ctttatgaaa gctgattttg
    21541 agaaacgtct ggaaccaaaa ggcattcctt tagatgtcat caatatggct gattatggta
    21601 tgatgaatgg cgaaaaagtg ttagatcaag caatcgcgct cataggtgaa taaatagaac
    21661 agtataacta tcgaacaagc gatccaaaaa atagatcgct tgttttttcg tatatttttt
    21721 tagggcgaat aatatgaatc atttttgggg tagaaggctt ctgacgagag atattaaagc
    21781 aatagactgt gaggaggtaa atttaccaaa ttatgagaag atcgcagcag tggaacgttt
    21841 gggcaactgg attctttgtc atcgctgtgg aatgaggacg tccgtcattg ttggacagct
    21901 tgcagattac ggttattttt gtacacattg tctatattta gggtgatgcg acactcaaca
    21961 agatttatat ttgtttgatc agcctgaagc aaaacctcga gaagtcgtct ttttttggac
    22021 aggacagctt actgaaaaac aaacggaaat cgcaaagaga atactttgcc attcagaaaa
    22081 aagacatcat cttatttggg ctgtaacagg tgcagggaaa acagagatgc tttatcctat
    22141 tttagtggaa actttaaaag ctggaggaag agtagcgatt tgtacaccgc gagtcgatgt
    22201 ttgtaatgaa ttgtttttac gctatcgtta tgtttttcca gaagaaaaaa tcacgttgct
    22261 ccatgggaat acagcaacgg cttatacctt tacttctttt gttatctgta cgattcatca
    22321 gctataccgt ttttatcggt cctttgattt aatagtgatc gatgagatcg atgcgtttcc
    22381 ttataacggg gatgctgggc tagctcacgc tgtgcaaaca gcaatcagac caaacggccg
    22441 attcatctac ttaagtgcca cgcctgatga gaagttacta aaggaaatca agcagacatt
    22501 tgagctccac aaacttgcct tgcgctttca tcggcgcttg cttcctgaac ccgtgcttgt
    22561 tttcatgaat aattggcgac aaaaatgtgg aaacaaaaag aaaatcaact ctttggtgcg
    22621 gatcattcag caactaatca aagaaaaccg tatcctttta ttttgtccaa gtattacgat
    22681 gatgcatcgt ttaaaaatca cactgcaaga agcttttcca gaatatgaga taacagatgt
    22741 ttcttcacaa gacgatcaac gggcaaagaa agttcagaaa atgcgagaag caatatacga
    22801 gatactgtta accacaatga tcctagaaag aggagtcaca tttgaaagaa tctctgtcat
    22861 cgttttagga gcagatcatc cagtttttac taaatcctct ttggtgcaaa tcgcaggaag
    22921 agctgatcgt aaaggtcctt atacgaacag tcgagtctat tttttctatg aagaaaaaac
    22981 ttcagctatt cgaaaagcct gtcaggaaat caaagaaatg aacgaagaag ggaagcagat
    23041 gctgtgagat gtagttgctg cggtaaagac atcattcaaa atttaacatt cagcgagatc
    23101 atcggagtgt cgaaatctag acttcctcag acatgttcag tttgccgcgc acaattccat
    23161 ttattagaag caaaaggttg tgcaggttgt caaaaaccaa tccatttgaa atacgaggag
    23221 acgaaaaaga aagcaaatac tagtttcgtt tactgcaacg actgtcaaga atggaagaag
    23281 aaatatcctg catatgattt tcaacaccgc gcctttttta cgtacgatga aaagatgcag
    23341 gcttggatca atcggtacaa gtttatggga gatatccgat tagcagggac ttttgcatat
    23401 aaatggactc agataaaaaa agattacccg gcatatattt attgtccaat acctttatct
    23461 gaaaaaaggt ggctagaaag aggattcaat caagtaagcg agatgttgaa agcagcaaaa
    23521 attccttttc agatgctgct caaaagagag caacatctgc ttgctcaagc aaaaaacacg
    23581 cgaaaggaaa gattggagat gcctcagcct tttgagcttg ccgtacctct ttctaagata
    23641 caacataaaa aaatattgat tattgacgat gtctatacaa caggacagac gctttttcat
    23701 gcagcagatt gcttgcagaa cgcacagccg aaaatcatcc gaaccatttc tttggcaaga
    23761 tgaatcagat gtggaaattt gatagcgatt taatttgcaa ataacctaga gttcgatata
    23821 atagaattaa gaagagggaa agagtggtcc ttctccttct tgattgtggt agacgaaagg
    23881 ggtaattttt atgtttagat ataatgtacg cggcgaaaat atcgaagtaa ctgaagcgat
    23941 tcgcgactac gttgagaaaa aagtaggcaa actagaacgc tatttcagtg acgcacccga
    24001 tgcaacggcg catgtgaact taaaagttta tacagaaaaa acagcaaaag tggaagtaac
    24061 gatcccatta ccttatcttg tattacgtgc cgaagaaact tctccagatt tatacgcaag
    24121 tatcgatttg gttgttgaca aattggaacg ccaaatccgc aaattcaaaa caaaaattaa
    24181 tcgtaaatcc cgtgaaacgg gcatgaatac tgcagatgct gctgctttat tcaatgaaga
    24241 ggacgaaaac gaaaatgatt ctgaattaga tatcgtacgt acgaaacgcc tttcattgaa
    24301 accaatggat agtgaagaag cagtcttaca aatgaacatg ctgggacata acttctttat
    24361 ttttgaagat gcagaaacaa atggtacaag tatcgtttac cgccgtaaag atggaaaata
    24421 cggactgatt gaaacagact gatcagcctt acttaaataa caacgaaaac ttgcagcagc
    24481 tactgacagc tgccgcaagt ttt
//
LOCUS       DASHXG010000034        24271 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.034, whole genome shotgun sequence.
ACCESSION   DASHXG010000034 DASHXG010000000
VERSION     DASHXG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.034"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..572
                     /locus_tag="U2R59_001711"
     CDS             <1..572
                     /locus_tag="U2R59_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8966099.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="U2R59_001712"
     CDS             576..1217
                     /locus_tag="U2R59_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966100.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="U2R59_001713"
     CDS             1214..2131
                     /locus_tag="U2R59_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HEM8966101.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="U2R59_001714"
     CDS             2128..2799
                     /locus_tag="U2R59_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966102.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="U2R59_001715"
     CDS             complement(3340..3828)
                     /locus_tag="U2R59_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HEM8966103.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="U2R59_001716"
     CDS             complement(4029..4295)
                     /locus_tag="U2R59_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEM8966104.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="U2R59_001717"
     CDS             complement(4295..4558)
                     /locus_tag="U2R59_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8966105.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5034..5219
                     /locus_tag="U2R59_001718"
     CDS             5034..5219
                     /locus_tag="U2R59_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8966106.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="U2R59_001719"
     CDS             complement(5361..7184)
                     /locus_tag="U2R59_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEM8966107.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="U2R59_001720"
     CDS             complement(7782..10487)
                     /locus_tag="U2R59_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEM8966108.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="U2R59_001721"
     CDS             complement(10793..11740)
                     /locus_tag="U2R59_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HEM8966109.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="U2R59_001722"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="U2R59_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEM8966110.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="U2R59_001723"
     CDS             complement(12375..12737)
                     /locus_tag="U2R59_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8966111.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="U2R59_001724"
     CDS             complement(12748..13869)
                     /locus_tag="U2R59_001724"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEM8966112.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="U2R59_001725"
     CDS             complement(13885..14235)
                     /locus_tag="U2R59_001725"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEM8966113.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="U2R59_001726"
     CDS             complement(14365..15876)
                     /locus_tag="U2R59_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8966114.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="U2R59_001727"
     CDS             complement(16198..17550)
                     /locus_tag="U2R59_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEM8966115.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="U2R59_001728"
     CDS             complement(17703..18779)
                     /locus_tag="U2R59_001728"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEM8966116.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="U2R59_001729"
     CDS             18975..20720
                     /locus_tag="U2R59_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HEM8966117.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="U2R59_001730"
     CDS             complement(21000..21437)
                     /locus_tag="U2R59_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HEM8966118.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="U2R59_001731"
     CDS             complement(21421..22794)
                     /locus_tag="U2R59_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966119.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="U2R59_001732"
     CDS             complement(23116..23604)
                     /locus_tag="U2R59_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966120.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="U2R59_001733"
     CDS             complement(23626..24228)
                     /locus_tag="U2R59_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8966121.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6958 a         5166 c         4487 g         7660 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agcccaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgcc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctt caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttccaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc t
//
LOCUS       DASHXG010000035        24258 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.035, whole genome shotgun sequence.
ACCESSION   DASHXG010000035 DASHXG010000000
VERSION     DASHXG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.035"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            139..996
                     /locus_tag="U2R59_001734"
     CDS             139..996
                     /locus_tag="U2R59_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEM8966122.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1111..2031
                     /gene="pstC"
                     /locus_tag="U2R59_001735"
     CDS             1111..2031
                     /gene="pstC"
                     /locus_tag="U2R59_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEM8966123.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2031..2915
                     /gene="pstA"
                     /locus_tag="U2R59_001736"
     CDS             2031..2915
                     /gene="pstA"
                     /locus_tag="U2R59_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEM8966124.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2930..3736
                     /gene="pstB"
                     /locus_tag="U2R59_001737"
     CDS             2930..3736
                     /gene="pstB"
                     /locus_tag="U2R59_001737"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEM8966125.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3752..4510
                     /locus_tag="U2R59_001738"
     CDS             3752..4510
                     /locus_tag="U2R59_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEM8966126.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4523..5200
                     /gene="phoU"
                     /locus_tag="U2R59_001739"
     CDS             4523..5200
                     /gene="phoU"
                     /locus_tag="U2R59_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEM8966127.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5438..5737
                     /locus_tag="U2R59_001740"
     CDS             5438..5737
                     /locus_tag="U2R59_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966128.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5763..6470
                     /locus_tag="U2R59_001741"
     CDS             5763..6470
                     /locus_tag="U2R59_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEM8966129.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6467..7234
                     /locus_tag="U2R59_001742"
     CDS             6467..7234
                     /locus_tag="U2R59_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HEM8966130.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7334..8902
                     /gene="liaX"
                     /locus_tag="U2R59_001743"
     CDS             7334..8902
                     /gene="liaX"
                     /locus_tag="U2R59_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HEM8966131.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9199..9519
                     /locus_tag="U2R59_001744"
     CDS             9199..9519
                     /locus_tag="U2R59_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEM8966132.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9519..9869
                     /locus_tag="U2R59_001745"
     CDS             9519..9869
                     /locus_tag="U2R59_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEM8966133.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10036..10974
                     /locus_tag="U2R59_001746"
     CDS             10036..10974
                     /locus_tag="U2R59_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEM8966134.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10989..11819
                     /locus_tag="U2R59_001747"
     CDS             10989..11819
                     /locus_tag="U2R59_001747"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEM8966135.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11863..12888
                     /locus_tag="U2R59_001748"
     CDS             11863..12888
                     /locus_tag="U2R59_001748"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEM8966136.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12903..13841
                     /gene="galU"
                     /locus_tag="U2R59_001749"
     CDS             12903..13841
                     /gene="galU"
                     /locus_tag="U2R59_001749"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEM8966137.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13966..14406
                     /locus_tag="U2R59_001750"
     CDS             13966..14406
                     /locus_tag="U2R59_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEM8966138.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14409..15011
                     /locus_tag="U2R59_001751"
     CDS             14409..15011
                     /locus_tag="U2R59_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8966139.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15079..16185)
                     /locus_tag="U2R59_001752"
     CDS             complement(15079..16185)
                     /locus_tag="U2R59_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEM8966140.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILSGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16395..17396
                     /gene="ccpA"
                     /locus_tag="U2R59_001753"
     CDS             16395..17396
                     /gene="ccpA"
                     /locus_tag="U2R59_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEM8966141.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17732..20077)
                     /locus_tag="U2R59_001754"
     CDS             complement(17732..20077)
                     /locus_tag="U2R59_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEM8966142.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20356..21258
                     /locus_tag="U2R59_001755"
     CDS             20356..21258
                     /locus_tag="U2R59_001755"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HEM8966143.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21471..23246
                     /locus_tag="U2R59_001756"
     CDS             21471..23246
                     /locus_tag="U2R59_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HEM8966144.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23503..>24258
                     /locus_tag="U2R59_001757"
     CDS             23503..>24258
                     /locus_tag="U2R59_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8966145.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT         7750 a         4334 c         5089 g         7085 t
ORIGIN      
        1 atagcataga aacttttaat gagatagttt tttttacaat tatgagaatt tattttgtta
       61 tttaatgatt ttgattcgtt ttcatcaagt aatgaaaatg ataaaataaa catactttag
      121 gattaaagga gatttctaat gaaaaaactt aaattattct taccaataat aggattagcc
      181 attcttttat caggctgttc aaagtggatt gatcgaggag aatccattac ggctgttggc
      241 tcttctgctt tacagccttt agtagaaaca gttgctgaaa cttaccagac agaaaatcct
      301 ggaaaattca tcaatgtaca agggggcgga agcggaactg gtttgtctca agtacagtca
      361 ggagcagtcg acatcggaaa ctctgatttg tttgcggaag aaaaatcggg gatcgatgcc
      421 tcagcattag tcgatcatcg agtagcagtt gttgggatca ctcctattgt gaacaaggat
      481 attggcgtaa aagacatcag tatggaaaac ctgaaaaaac tatttacagg cgagatcaaa
      541 aactggagtg aagtcggtgg aaaagatcag ccagtagtta tattgaaccg cgcttcagga
      601 agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc tgttcaggca
      661 caagaacaag attcaagcgg aatggtgcgc cagatcgttg ccgacacacc cggtgcaatc
      721 agctatgttg ctttttctta tgtttccgat gatgtagata cgttgaatgt taacggtgta
      781 gaaccgacag atgaaaatgt gacaacgaac aaatggacga tttgggcata tgagcatatg
      841 tacacaagag atcatccaaa aaaactgaca aaagaatttt tagactatat cttatctgat
      901 gaagtacaag ataacatcgt tggagaacta ggttatatcc ctgtttctca tatgaaagtc
      961 gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat ttacaaactt
     1021 agctaaactt ttacatgtta ttaaaaccaa attgatgttc aatttgtaca ctgagtgagt
     1081 atgttaaacc tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt attattaaca
     1141 aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt atgtatcgcg
     1201 ctgatcgtgt tggttgtatt atctattttt tattttgtag ctagtaaagg attggccacc
     1261 ttttttactg ataagatcaa tgtatttgat tttctgtttg gtacagattg gaatccaagc
     1321 caaatcggag caaatgggaa accaatggta ggggcattgc ctatgatcac aggttcgttt
     1381 attgtgacct ttttatctgc tatcgttgcc acgccatttg ccattggtgc agcagtattc
     1441 atgacggaga tctctcctaa aaacggaacg aagatcttac agccggtcat cgagctgctt
     1501 gtaggtattc cttctgtcgt ttatggtttt atcggtttat cagttatcgt gccttttgtc
     1561 agaagtattt ttggcgggac agggtttggt atcttagctg gtacatttgt gttgttcgtt
     1621 atgatcttgc cgactgtcac aacgatgact gttgatgcat taaaggcagt gccacggcac
     1681 tatcgggaag cttcattagc gcttggtgcc acaagatggc aaacaatcta caaagtcgtg
     1741 ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc tcgtgcgttt
     1801 ggtgaagcct tagctatcca aatggtcatc ggtaatgcag cattgatgcc aacaggactt
     1861 actactcctg cttctacatt gacgtccatc ttaacaatgg gaatcggaaa tacaatcatg
     1921 ggaacagttg aaaataatgt gttatggtca ttagcgctga tcttgctatt gatgtcatta
     1981 ttctttaata tcgtgatccg tatgattggg aagaaaggag agctgaaata atgaacgcaa
     2041 aacgctcaga taaaattgct acaggtgttt tatatatagt ttcggggatc atcgtattga
     2101 ttttagcagc tttactactt tatatcttag ttcggggaat accgcatatt tcatggtcct
     2161 tcttgaccga accttccaaa gcctaccaag aaggcggtgg aatcgggatc cagctattta
     2221 actcgattta tttgcttttg atcacgatga tcatcagttt tcctatttct ttaggtgcgg
     2281 gtatctatct ttcagaatat gctggaaaaa actggctaac agatgtgatt cgcacgtcga
     2341 ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt attcggtttc ttggttttcg
     2401 ttattcaatt ccagtatggt ttctcgatta tttctggtgc attggctttg actgtattca
     2461 acttgcctct tttgactaga acagttgagg agtctttaca agcggtccat tacacacaac
     2521 gagaagcagg attggcctta ggtttgtcac gctgggaaac agtgataaaa gtggtggttc
     2581 cagaagcgac accagggatt ttgactggtg tgatcctaag ttctggaaga atttttggtg
     2641 aagcagctgc attgatctat acggctggac aaagtgcacc tgcgttagat tttacgaact
     2701 ggaatccatt aagtgtttca agcccgatca gcattttccg tcaagctgaa acattagctg
     2761 tccatatttg gaagatcaat acagaaggca cgatgcctga tggtgtttct gtttcggctg
     2821 gcgcttctgc cgtgttgatc attgctgttt tactgttcaa cttcggcgct cgtgcgattg
     2881 gcaaacgatt ataccgaaaa atgacttcag cctaaggaga agaagcaaaa tgaaaaaata
     2941 taactggaat gaaacaaatg tcatcaccat gccaaaagag aaagaagtag cactatatac
     3001 ggatgatcta catgtctggt atggcgacaa tgaagcaatc aaaggagtgg atctggaatt
     3061 tgaaaaaaat aagatcactg cactgattgg tccttccggc tgcggaaaat ctacgtatct
     3121 tcgttcgttg aatcgaatga atgatgggat cgctaatacg aaaatcactg ggaaaatcat
     3181 gtatcaaggc gtagatatta atgcgcctca agtggatgtt tatgagatgc gcaaacggat
     3241 tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca atattacatt
     3301 tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg ttgaaacaag
     3361 cttgaaacaa gctgccttgt gggaccaagt aaaagacagc ttggacaaaa gtgccttggc
     3421 tttatctggc gggcaacagc aacgtttatg tattgctcgt gcgatcgcga tgaaacctga
     3481 tatcttgctg ctagacgagc cggcaagtgc tttggaccct atttcgacag gaacggttga
     3541 agaaacactt gtaaacttga aagaagacta tacgatcatc atcgtgacgc ataacatgca
     3601 acaagcagct cgtatcagcg actatactgc ctttttctat ctaggaaaag taatggaata
     3661 tgacaaaact aacaagatat ttaccagacc aaaaattcag gcaaccgaag attatgtgtc
     3721 cggtcatttt ggttaagacg gaggcctcaa catgacaaaa gaaattattt catctaaaga
     3781 tcttcatctg tattatggaa agaaagaagc actaaaaggg atcaatctaa gtttcaatca
     3841 aggggaaatc actgcgatga tcggtccttc tggttgcggg aaatccactt atctgcgttc
     3901 tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc accggaagtg ttttatataa
     3961 agacaaagac atctatggtc caaaaacaga tgttgttgaa ctaagaaaag aaatcggcat
     4021 ggtattccag cagccaaacc catttccttt ttctatctat gaaaatgtca tctatggatt
     4081 gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag aaagcctgaa
     4141 ggcagcgtct gtttgggatg atgtgaaaga caaattgcat aaaagtgctt tatctttatc
     4201 cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc cggaaatcat
     4261 cttattggat gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa tcgaaagtat
     4321 gctgttagaa ttaagagagc ggtatacgat gatcatcgtg acccataata tgtctcaagc
     4381 ttcacgtatt tcagataaga cggcattctt tttagatggt cacttgatcg aatacaacga
     4441 tacgaagaag atattcatga atccagaaaa acaagagaca gaagattata tttcaggtcg
     4501 atttggataa ggaggaaacg gaatgctacg tacacaattt gaagaagaat tgctgaatct
     4561 ccataatcag ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca agtcagttcg
     4621 tgcatacatc aaacacgata aaatcttagc ccaagaagtt atcgaaaacg atataaatat
     4681 caataacatg gaaacacgct tggagaagaa aagttttgaa atgatcgcat tgcaacagcc
     4741 agttacaact gatttgcgta tgatcattac ggtcatgaaa gctagctcgg atttagaacg
     4801 tatggccgat catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag ggcagacgag
     4861 aataccggaa atcgaaaaag agatctccga tatgtccgat tatgtgaaaa aaatggtgga
     4921 caacgtccta gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga tcgccaatat
     4981 ggatcaaaga gtcaatgact atttcaatcg aatctataat gcaacaatca aaaatatgca
     5041 ggaaaatcct gagacagtca tcagtggaac agactacttg aatgttgcca gttatctaga
     5101 acggatcgga gactatgtga caaacatctg tgaatggatc gtctacttgg ctacagggaa
     5161 aatcactgag ttaaatacga accacaatga gattttctaa actgaagctg tgattatgcc
     5221 gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt ctgcatcaag
     5281 taataagaac agtcaaacaa aaaatagctc ctcatatttt tcgtttggct ggacttatta
     5341 ccgcagatgc aagcttttga acaccgttta ttcgggaaag ggtttgtgac aaaacatgtc
     5401 acaaaccctt ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat
     5461 cactatattt tttatttgtg tgcttacttc atgggttatt cagcatcaag ctgctttata
     5521 tgaagtacct gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc aattgattac
     5581 aggaagactg atgaacacgg atcaaaaagg agaatcgatt tatttatcgg ttccttatca
     5641 aaaaaatcaa atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca
     5701 tggagatgaa tggcagctag tagcaaaaaa aaaatgatgg ctggcttttc ttcttcacaa
     5761 gtatctccat tggcgccatg ttgcttattg gcggaaaaca gggtctattt gctttaggaa
     5821 gtctcatcat caatatcgtt ttacttttac ttttgttgct catctttact aaaacagaag
     5881 ggatttctct attaaatata tctatcctgt tcgtcgttat agggatgatt attagcatat
     5941 tggctttaga tggatggaat agaagcagta taatcaaaat ttcagctgca gttacgagtg
     6001 tttttttagc attttttatt tgtcttttga caatgaatca ttggaaagac caaggactgc
     6061 gctatgagga actgaattat ctgacacgac cgtatcgttc tgtttttctt tctagcgtac
     6121 tgattggaac agctggagga acactcgata ccgttatcac agtcattgcg acattagaag
     6181 aattgactaa gcgacaacca gaaataacag cgaaacagtt atggctttca ggaaggcaag
     6241 tgggtcgaga tgtgattggc tcgatgacca atatcctttt gttcgtctat atcagtgggt
     6301 cagttccatc gcttctttta tatttaggaa atcaatggtc gttcaaagaa acgatagaac
     6361 agcatttatc attggaattt ttacgcgtca ttgctggcag cttaggaata gtattatcga
     6421 tccctatctc ggtcctcttt tttctgactg taaggaggct gaaacgatga atgtacttat
     6481 tatacttgtt gggattttag caatcagcgt gctacttatt ggcggtacgc aaggtatgta
     6541 tattctttta ggcttattca tcaatttagg gatctttttc ctgttgttat tcggttatca
     6601 tcagaagtgg ccgatactgg cattgtcggt cataggattt ttattgattg ctgtggttat
     6661 cttatttttt atcaacggtt ataatctaaa aatgcgtgca gcttttgtga gtatactgat
     6721 ctttttattt tgtttcctac tattgcttcc tatcactgat tttttagcga tccaaggttt
     6781 tacatcggta gaactagaag aattatctgg cttagataag actttagcga ttgattttag
     6841 attacttacg agatcgttgc ttctgattag tcttagtggt gctgttttag atgctagtgt
     6901 agcaatttct agtgggacat tcgaagtata tcaggcaaat ccgcaattat ctttttacca
     6961 attgcgccat tctagtttcg ctattgctaa aaaaatattg gcgtcaacag taatgacact
     7021 tctttttgca ttcatgggaa gttctttagc gttgatcctc tggtttattg atttagacat
     7081 tccttttcag caagtgatca atgaaaaatc atttgttcta gaatatacga tggctattct
     7141 taccacattg tctgcactac ttgttcttcc tttaacctgc gtgactacag catatctctt
     7201 tacaaaaaag aaagaacaac tcaagatgga gtaaaagtta caacttaagt cctatgacat
     7261 ttttactgaa tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa
     7321 ggaggcaatt tccatgaaag aaagagaacg tattttagat ttagtgaaaa aaggaatcct
     7381 ttcgactgaa gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaagca
     7441 aataaaaaaa gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca
     7501 attgatcgat aaacttgaaa acggcgaaga agaaatttct gagccagttg atccaaagga
     7561 aagagaaagg caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc
     7621 gaataaaact tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca ataaggcagc
     7681 acgcaatgag aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt
     7741 gacagaagaa gaattagcac agcgtcagac gttagaagca gaaatcaaag aattagaagc
     7801 tagtggcgat acactgttag aagaacaatt gaaattagaa gcagaattaa aagatatccg
     7861 taagaatcaa tggtctgaga aaaaagaaac gtttactgat aagtttgaat tgccagatga
     7921 ttggaaagat caagcaacag atacactgaa tcaagtaggc gaaaaaatgt cagaagctgg
     7981 atcacagtta ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtgaatga
     8041 caacatggaa tggaaagatg tcagcttacg tgtccctggg attgcgacaa cgaaatttga
     8101 gcatgaattt tactatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg
     8161 aaacgtgacg ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta agatcaaact
     8221 ttacggaaaa atgggtgctg aaccatttga agcattctct gaacggagcc agattgaggt
     8281 taatgaagat catatctcct tccaaattcc aaataaacgt gtgcgtgcag accttgtttt
     8341 ctacttacct aaacgagtat acgaccacgc agctattaaa cttctaaatg gcaacatcat
     8401 gattgaaaca ttggaagcta aagatattta tacaaaatct acgaatggta acatcatcgt
     8461 ggaccaatta actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg
     8521 aaacgggaac atcttagatt ctattatcga aacagtaaat ggtacagtga catttggtgc
     8581 gacagcagaa aacctttctg tgtctttggt aaatggtgat gtacgtctta cgattaaaga
     8641 agataatttg aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag tcgctttacc
     8701 agatggcatc ggtttggaag gacatgctaa aacaagtctt ggaagtatca acagccgtct
     8761 gtccaattac gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg
     8821 tcgtgtttca gatggtgaaa tcacgcaagt gcaactttca acgacaacag gaagtatcta
     8881 tttaaaagat acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag
     8941 aagcgatttt gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt gccgataggc
     9001 tatctcttga acaccgttta ccaagagatt atgaacctgc caattatcgc cgagtcacaa
     9061 ggaataattt cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt gaccgagaat
     9121 tttgcagaaa gacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata
     9181 gtagaacaga ggtgagacat gatgaaaaaa aagttgacaa aatccaataa aaatgttgtt
     9241 ttgacaggga ctttagcagg aataggagaa tacatcggga ttgatccgac tgttatccgt
     9301 gtgctttatg tattcctgag cttagttgct tttggaagtc caatcatttt atacatttta
     9361 ttagctttga ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca
     9421 tattatgaaa aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa acgcaaagaa
     9481 gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt caacgtattt
     9541 tagttaatac gttaacattc atatcattgg ctgttctttt tcctgcgatg gtccatgtga
     9601 gcagtatttg gacggccgtt cttgccagct tcgtattgtc tgtgttgaat atgtttgtca
     9661 aaccgatttt gacgatactg tccctgccct ttacattagt cacattggga ttgtttacgt
     9721 ttgttatcaa tgcagcgatt cttaaaatga cctccttttt tgtgggagca gaacatttta
     9781 gtttttcttc attcggtgca gcgttgttag tagctatctt gatgtcgctt gtcaatgtaa
     9841 ttgtcagtga acataacagt agaaaataaa agaaagctgt gccgaactat cggcgcagtt
     9901 tttttattta gaatcaggaa tgcgttttct attacattgg taattaaata aaaacgtttt
     9961 ttttaattgg tagtactttt ggctagacaa tgataaaatg atagagaaca ctctaataga
    10021 aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtgaa aaaattatct
    10081 ttggaaatcg tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac tggggacatc
    10141 tcacgcccag gactagagtt gactggttat tttaattatt attcccataa tcgtttacag
    10201 ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga gcgtttgatc
    10261 atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag aggattaccg
    10321 gctccagaag aaatgatcca ggcagcaaat gaaaatggga tagctgtact gcgttctccc
    10381 atctcaactt ctcgtttatt aggagaatta tccagttatt tagatggtcg ccttgcccct
    10441 cgaacaagtg tccacggtgt tttagtggat gtttacggat taggtgtact gattcaaggt
    10501 gacagtggga taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg tcatcgattg
    10561 atcgcagacg atcgagtaga tgtttatcag caagatgaat taacggtgat cggagaaccg
    10621 cctaaaatcc tggaacatct aattgaaatc cgaggaatcg ggatcattga tgtaatgaat
    10681 ctttttggtg cgagtgcggt acgtggctct atgcaagtcc agttggctgt ttatctggaa
    10741 gcatgggcaa aagataagaa atacgaccgt ctgggctctg aagacacgac cgttgaaatc
    10801 gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa cgttgcaatc
    10861 atcattgaag tagccgcgat gaatttccgt gcacgtacaa tgggctttga cgcaacgaaa
    10921 acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaacga ctagcaagga
    10981 gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtaggg attcctatct
    11041 actggtatgc attgatcatc gtatcaggta tcattatcgc catgtggctt agcagcagag
    11101 aggctgttcg ggtaggatta aaagcagatg atgtgacaga ttttatgttg tggggattgc
    11161 ctatctccat tattggtgct cgcttatatt atgttttatt tgatcttccc cagtatatag
    11221 ctgatccaat ccaaatattc aatatccgtt caggaggctt agctatttat ggcggactga
    11281 ttgcaggcgc gatcacgctg tattttttta ctaaatatca ttttatttct ttgtggactt
    11341 ttttagatat cgctgcacca agtgtattat tagcacaggc aatcggtcgt tggggaaatt
    11401 tcatgaacca cgaagcatat ggaccagaca cgacgcgaag cttcttagaa agtctgcatt
    11461 taccgcaatt catcattgat aatatgtata tcgaagggat ctatcgtcaa ccaacatttc
    11521 tttatgaatc actttggagt ttgattggat ttattttgct tttgttttta cgaaagaaac
    11581 cacacctttt gaaaaaaggc gaagtccttt tatgttatct aatgtggtat agtttcgggc
    11641 gtttctttat tgaaggatta cgtacagaca gtctttactt tttaggtgtg atccgtattt
    11701 ctcaattatt atctgctgtg ttatttgtcg gtacattgat tctatttatt tggcgcagaa
    11761 aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa attatctgat
    11821 ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta tagagtagcg
    11881 gttttaggac caggctcttg gggtactgct ttggcacaag tcctcgccga aaacggacat
    11941 gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac ccaacacacg
    12001 aatcaacgtt atttaccaga tcattatcta cccgattcca tccaagcatt caccaatatg
    12061 gaagatgcag taaaagacgc agatgcggtg ctattcgtca ttccaacgaa agcaatacgt
    12121 tctgttgcaa aagaactagt gcctaaattg aatacaaagc cagtgatcat ccatgcaagt
    12181 aaaggattag aacagggaac acataaaagg atctctgaca tcttgttaga ggaaatccca
    12241 gcagaaaaaa gaaaagctgt tgttgttctt tctggaccaa gccatgcaga agaagtagcg
    12301 aaacatgaca tcactacgat cacagctgca agtacagatg caaaagcagc aaaatatgta
    12361 caagagctgt tcatgaataa ttattttcgg atctatacca atcctgatgt gatcggtgta
    12421 gagatggggg cagctttgaa aaatattatt gctattggtg ctggcgctat tcacggctta
    12481 gggtttggcg ataatgcaaa ggcagcaatc atgacgcgcg gattagctga gatcagccgt
    12541 ttaggtgtag caatgggtgc caacccgctg acctttatcg gattaagcgg agtaggcgat
    12601 ctagtcgtta cttgcacaag tgttcattct aggaactggc gcgcaggcaa cttgttagga
    12661 caagggcagc ccctagaaga ggtgctagcc aatatgggaa tggtcgttga aggtgtgaat
    12721 actactcaag cagcgatgga actagcccaa ataatggaaa tcgaaatgcc catcactcaa
    12781 acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa agaaatcatg
    12841 ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag gagcgaatgt
    12901 atatgaaagt caaaaaagca gttattccag cggcaggatt aggaacaaga tttttaccag
    12961 caacaaaagc tatggcaaag gaaatgttgc caattgttga taaaccaaca atccagttca
    13021 tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca ggaaaagcta
    13081 aacgaccaat cgaagatcac tttgattcaa atattgaatt agaaacaaac ctaagtgaaa
    13141 aaggaaagac cgaattattg aaattagtag aagaaacgac agatgtcaac ttgcatttca
    13201 tccgtcaatc tcatccaaag ggtttaggac atgccgttct tcaagcaaga gcctttattg
    13261 gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagatgaa gtaccattga
    13321 cacagcaatt aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc gttatgcaag
    13381 ttcctcatga tgaaacttca aaatacggaa ttatcaatcc aggagaagta ttggaagatg
    13441 ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca ccaagtgatt
    13501 tagctattat tggacgttac ttattgactc cagaaatttt tgatgtattg tccgagcaac
    13561 aaccaggagc cggaaatgaa atccaactaa ctgacgcaat cgatacattg aataaaacac
    13621 aacgcgtatt tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac aaatttggtt
    13681 ttatgaaaac aagtattgaa tatggtctaa cacatccaga agtaggtgca cctttacgtg
    13741 agtatatcct gtctttaggt aaaaaattag aagcagaagg aagcaagatc gatcataatc
    13801 caaaaggaat aacagaaatc aaagaagaaa agaaaaaata accctttttt ctaacgagct
    13861 tcagctgcta attgaataaa aagtagttga agctcgtttt tatttgttta aaaaacacga
    13921 aaatgctatc cttatagaaa agagagacaa gaagggagtt tgatcatgtc aggaggagaa
    13981 attgcaggat tgatcgcagc aatcgccttt gcgatacttg tcgtttttat cgttcgtgtg
    14041 ttgttgcaag tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga agcaaatacg
    14101 acgatcgaaa tcgtcacaaa agacgtagat cttttgtcta gacaagtaga aggcttgctg
    14161 gtcaaaagta atgaactgct cttggatatc aatggaaaag tcgcaacgat cgatccattg
    14221 ttcacagcag ttgctgattt aagtgaaagt gtatcagaac ttaatcattc tagtaaaaac
    14281 atcgcgacga aagtcggcgg aatcggtaaa acgacagcta aagcgacggt tgccggaaaa
    14341 gtcggtggga cagcgatgaa attttttaaa aacaaaaaac atactgaaac gacaggagga
    14401 aaataaaaat ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga ggaacagccg
    14461 cagcaatcgc cgcgttattg ttagcaccaa aatctggtaa agaacttcgg gatgaattag
    14521 ctgcccaagc ggatgatttg atggatatgg cttcagatta cacagatatg gcgaaagaaa
    14581 aatcgactga gttaacaggt attgcaaaag aaaaagcgca agatctttct caacaagcag
    14641 gtgatctagc aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa gcaggaagtg
    14701 aatctgacga tatcttgtta aatcttaaag aacaatcagc tgacttatct aatcgtttca
    14761 aaaaaacggc agaagatatg aaaaaacctg cagatgaatt aggaagtatt gctaaagata
    14821 cttcagaaga tatcatgatt gatgtaaaag acgctgctgg taaagcagga gatactgtca
    14881 atgaaggaat gtcagaagca aaaccagttg cagatgacac aaaagaaatg atgaaaatgg
    14941 caaaagaaga tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca gattcatcta
    15001 caaatcacta aaatcactaa aatcacaaat ttatagaata aaaaggtggg agcggactag
    15061 ctctcacctt ttttactctt atttttctaa aactagtaat tcttttggtg tagtcgtgaa
    15121 tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc ctactttttc
    15181 aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta ctaagtcatt
    15241 tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac ctaaacggtg
    15301 attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt gatcaagttc
    15361 acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt caagagtgat
    15421 gttgtatatt ttttcttgga agtcggttgg tttttgataa gcaattgtac gagtagcatc
    15481 actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat tcggtgaaat
    15541 cttcgtgttt cctggtgtac catgagggct tgcagcattt gctcctgcaa ggactaatgt
    15601 gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcgattt ctgcaatgat
    15661 cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg caacatcggc
    15721 ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca gttgtagacg
    15781 ttggatgatg gaagctagat cagtgtaaga atccgttccc gacaagatat cagagatagc
    15841 atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag gctgaccata
    15901 gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta aatagccacg
    15961 gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag gagtgaaaag
    16021 gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag gatcactttc
    16081 gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt cgacttggtg
    16141 ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc aacctacttt
    16201 ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc aacgttctaa
    16261 aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca attcttgaga
    16321 ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata taaaatatga
    16381 ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg agagaggcaa
    16441 atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtc aaaccagcaa
    16501 caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac gcagttgcgc
    16561 gtggcttggc aagtaagaaa acaacaacag ttggggtaat catccctgat gtcagcaata
    16621 tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac aaatacaata
    16681 ttatcttagc aaattcagat ggtaacgacc aaaaagaagt caatgtattg aataacttac
    16741 tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac gaaatccgtg
    16801 gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat ccagatgaac
    16861 aagtaggtag cgtaaacatt gattatgtat cagcaacaaa agatgcagta aacaaattgg
    16921 caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat cctatcaatg
    16981 gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta ccatatagcg
    17041 aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta gtcgatcgga
    17101 tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc atcggtattt
    17161 tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc atcacaagta
    17221 acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca caaccattat
    17281 acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa gaagaagtcg
    17341 aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca aaataataaa
    17401 aggacaacca ttcagaggtt gtgagcctgc cgtttaactc tgcgttacaa ggagcaattt
    17461 caaaaaacag catttcatgt ttgatgaata ttgtgactcg tgattcggag ttggcaggag
    17521 aacaccgttt attcgggaaa aggggttatg acaaaatttt gtttaatcct ttttttttgt
    17581 cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat
    17641 agatgctgca ttatgttcac caccatcaaa aaaataaggg actgtgacaa tactattgtc
    17701 acagtccctt attactgtgt attctattaa atcaatcatc tttctcatct gattctttgg
    17761 ttgcttgatt cgctcttgca taagctgaag cggtgttcca gtaatctgta tagttttcat
    17821 cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc gcccatagcg
    17881 attcaactgt ttttcctggt gtttggatgg attttttatt gacagtaact tttccaggtg
    17941 tttgaccagt aaatccagat acttttttct tcatcacatc agatgataat tcgaatttct
    18001 catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg attgatcaga ttggcaagat
    18061 aattagccga acgtatcctt gctttgctgt ccattccagt attgtcatcg tgccctgccc
    18121 agctactgat ggtaatagac ggagtagaga caattagcca tgaatctcgg tattcattgg
    18181 tagaaccagt ttttccgacc caatctgctt ttcctagatt tccgtttaag cttgagatgg
    18241 catctttgaa tggtgtagtg atttttgcat tgatcacact gcgcatcatg tcattcatga
    18301 tcgatgccgt tgcttccgaa tagatccgga cagagttgct ttcgtgttta taaattacat
    18361 ttcctgcgtt atctgtgatg gaatcgatga tatagccttc ttcatagacg ccgccgtttg
    18421 ctaaagcctg aaatccattg gtctgttgaa gcgtcgtgac atctactgta cctaaaggag
    18481 cagattcaac gccccaattg tcatttgccg ggtagttcat ctttgccaag tagtgctcgt
    18541 aagcatattg tttcgatcca ccggaattca acacatcttg atataagtga taagccggga
    18601 tattgttgga ccattctagt gactcacgga cggtttggaa ggtgttcgat ccttcgttag
    18661 tagcattgac gattttctcg ccagcatttt ctccttcttg ccaagttgtt gcataatctg
    18721 atacacggga ttctgatccg ataagcccca tgtcgattgc aggtccataa acaagaactg
    18781 gtttgattga tgagccagct tgacgttctg tatcgaaggc atggttattt tgattctgac
    18841 tgtaattccg tccgccaacg aatccgtaga tgcggccagt tctgttatcc atcaatacat
    18901 ttccggtttc tacttgactg ccagcaccat catctaacat gtatccataa ttttctacgc
    18961 cattttgcaa tgcagcatag acatctttat cgattgtcga atggattgta tatcctttat
    19021 tttggatcgt ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa tcagacatat
    19081 cagcgttgtc tttttcagcc aattgttgtg caatgattct tgttgcttca ttcatcacag
    19141 tataatacaa gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga aagtcttttg
    19201 taaggtcata ggcttttgct tcttcgtatt gttctttcgt aatttggcct tcacgataca
    19261 tactgaataa aacaaaatct tttctggcaa ggccggcaga aagatcttct tttagcgcac
    19321 ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg taatccagcg atataagcag
    19381 cttgcggcag cgtcacatct tttgcatcta caccaaagat tcctcttgca gcttcctgga
    19441 ctccagcaat gttttgtccc ttattattac gaccaaatgg tgagacattc aaatacgtag
    19501 caatgatctc atcttttgaa aagtattttt ctacttgtgc agaaagaatg atctcgtttg
    19561 ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg tttgactaat tgctgtgtca
    19621 aagttgatcc accagaagag ccaataccag tagcttcaga tactaatgct cgtaaaacag
    19681 ctttaggaac gtaaccttgg tgtttatcga agtattcatc ctctgtgctg ataattgcag
    19741 ttttcaataa aggtgaaatt ttatcagatg aaatagtcgt gcgcatcaga tctgtctgga
    19801 tttttgatat ctctgtatta tctgcataaa caatctttga cgtttctgta atgtttccta
    19861 gttctgtctg cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga taggcaaaat
    19921 agccagcgcc tattccaata cctagagctg cgaacatcaa aagaagaaca gtaataaaaa
    19981 cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt tctttttttc
    20041 ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca actaatggtt
    20101 ttatttcgct aattatagca aataatagaa caaaaaaaca gacaaggctg tttttggcag
    20161 gaatttcttt tttaaaagag ttaaaacgtg agaaaatgat cttttttata aaagagttct
    20221 taagcttttc tttagagaaa atttcagtta ctatggagaa cagggcaaag aaaaatcaat
    20281 cattttcttt gtatatcatc ttaccaatat ataggaattg ttagtaacaa ttgcctttca
    20341 aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa gaaaatgctg
    20401 ttaggagcag cagaagaagc agccagttat ggatcttcga cttttatgat ctatacaggc
    20461 gcccctcaaa acactagaag aaaagccatc gaagagatga atattgatgc cggaaaagcg
    20521 tacatggcag aaaacggtct aacaaatatc gtcgttcatg ccccttatat cattaatttg
    20581 gggaatacga tcaaaccaga aatgtttcct tttgccgtcc aatttctgag agaagagatt
    20641 gttcgtgcgg aagctttagg cgctactcaa attacacttc acccaggtgc tcatgtaggg
    20701 gcaggaacag aagccggaat tgctagaatt attgaaggct tgaatgaagt tttgacaaaa
    20761 gaacagacgg cacaaatcgc tttggagaca atggcaggta aaggtacgga aatcggtcga
    20821 acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt
    20881 acttttgaca cctgtcatac gaatgatgcc ggttataata ttaaagaaga cttttcaggt
    20941 gtaatggaag agtttgataa gatcatcggg ttagatcggc ttaaagtact ccatatcaat
    21001 gattctaaaa atccgcaagg ttcgcataaa gaccggcacg ccaatattgg ttttggaaca
    21061 atcggattcg acacgctgaa taagatcgtc catgatccaa tgtttgacaa tatttcgaaa
    21121 atcttggaaa ctccctatgt cggcaaagat aaaaagaaag cttacgcacc atatggaaaa
    21181 gaaatcgcca tgttcaaagc acaaatattc gatccagaag tgtttcctga gttattagca
    21241 gaagaagtga tactctaaga ttttctatct gacagcagca aaaaaggacc aggcacattg
    21301 ccttgtcctt ttttgtttaa gaaacaaagg agtgcttttt gcagtctttt tcatcatgca
    21361 tcttctcccc cctcttttta aatttagaca aacagggtat actggtagaa aagtaaaaaa
    21421 acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag atgctgaaca
    21481 ctttaaaacc cttgatcaac caactaaaaa agaaacatac atactttatt cttggcatag
    21541 ccctattatt tacaattatt cgtttgtatt tatatagtaa agcaatctat ggaacagaca
    21601 tgtcggcaac ctatgatgac cagctgctga ttcgctatgc tcaaaatatt ttggacggta
    21661 aatggctagg ggagtatacg actacaacac tttccaaagg aatctcctac agcttatttt
    21721 tagtacttgc acataaactg catctttctt atgcagtttt gttcggcatg ttcagtattt
    21781 ttgccagtat attggttgca ctcgcgttta aaccgatcgt gaagaacaag tatcttcttt
    21841 taagtttcta tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc
    21901 gaacgtatcg taatgccctc gtgattccgg ctgttgagat cattatcgct tgtttactag
    21961 ctatttatta ccgtaaatat agttccagca aaaaaatgct gccgtggttt ttagggctag
    22021 ctgtttcttt tcctttcttt tggttcattc gcgaagattc catctggctt cttcctttta
    22081 ctgtagtcgc gttaggcatc agtttcgtcc agatcttgct aggacaagac ttttctttca
    22141 aagaagcaaa gaagttaaaa gaacgaccat ttctcctttc gaaacaagaa tggctgaaac
    22201 tttcattgtt tttactccct ctagtcggtt tctccatcgt ctatcagtgg atcgaatata
    22261 aaaacgagac aacatatagt attgccgcca tcaatgaccg ttcgagtggc gaatttggac
    22321 gtttgatgaa acagctgatc cgaatagatg acgaaacgaa cttaaataaa gaaaacagtg
    22381 agatatgggt ctcgcatgct gcattaaata aagcattaga cgcatctcct acatttcatg
    22441 ctgtttctac tcgtattgac gaattgtata cgactcatgc gtggacccaa ggtggaaaag
    22501 taaaagaatt accaggagat atcatttttt gggcattgcg agatgtggta agcgaatctg
    22561 gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aatcaagaat
    22621 tagaagaagc ctatcaaaag ggaactatca aaaagaaaaa agaattctat ctgatgggat
    22681 caggggatgg aaagacgatg aatgatctgc caatcgtatt tgcttttctg aaatcaggat
    22741 atgcctatgc atggcgatac aaagatttcc atcaaggggg gaattatagt ttcggtacgc
    22801 aagaacaagt cgaacaggcc caagaattat tgaatcttcc actaatggat aattggatcg
    22861 atagcagtga tccgagaaca cctgatttcc agttgacaaa aacagcaaaa gtcgcgaatg
    22921 tcatgataaa aatttaccaa gttctggcca ttcccgtgct gattgcttca atagcaggga
    22981 tattacttat gatactagga accgcatttg caaaagctga tcgtgcctat tatagttcct
    23041 ctttgattgt agtcaccgga ttaatactga cacaattggt ttttcttttc ggcgtctcgt
    23101 ggttttgttc ttatgcgcca gaaaaaaagg attatttttt aagtgtctac actggcgcag
    23161 gcgtgccatt aacgcaattc atcgtagtaa caagcatgct agttttcagt aaattgaatc
    23221 tgaaaaaagc tttatcttcc aaataaaaac atactaagat tagaggagaa catcattgac
    23281 gaatgatgtt ctcctctatt ttctattttt agattatagt gaagagtgaa agaaagttcg
    23341 aacaaagcct tgaggactat gagtccctat caaaaaccga acttctttac tgtcatttta
    23401 gaatcaggtt tacgtatgtt ggggccatga gcccgtgtat aggaaattgg aatcgaaatg
    23461 aagcagtaaa gttctttcaa aacttaaaaa ggaggaaaac aaatgcctta cattcttgca
    23521 ttagatgttt caatgggaca cagctacagt gtcctataca aagacgacac ctgcttattt
    23581 gaagacgaga tcgaacacac tcaaagagga tttcatgcat tactcgaaga gatccagcac
    23641 ttgcctgaac gtccattgat tgtttttgaa gcaacgggga tttattccag accagtcgaa
    23701 aagttctttc aagatcatca cttttcttac tgtttgttaa acccgttaga agcgaaaaaa
    23761 cagatggaag aaaacacctt atgcagttgg aaaacagata aatcggatgc ccatcggctc
    23821 gcacagactc atcttaaaaa tcaacgtcag ccaaaagaag tacaaagcaa tttttactta
    23881 gagatgcgcg atttagcccg tttttatcaa gaaattgaga agaaaatcac tcgtctgcgc
    23941 atggatttac acaactgcct tcagttgact tttccagagc ttgaacagtt ctttttaaac
    24001 aggctgaccc cttacgcatt gatattgatc cgtctttttc cccatccaga ttttgtattg
    24061 gcatctactc ggacaaaaat aaaaaataaa ctgatcaacg aaacacggaa aaaaatctcc
    24121 gcgaatcgtg ccgagcaaaa ggcagatcaa atcatccact atgcacagtg tgcctatcca
    24181 gctgttgaaa aagacagtat ccactgtcaa aaaacgatct attacgctga acttctccaa
    24241 gatttactcg aacaaaaa
//
LOCUS       DASHXG010000036        23828 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.036, whole genome shotgun sequence.
ACCESSION   DASHXG010000036 DASHXG010000000
VERSION     DASHXG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.036"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(53..787)
                     /locus_tag="U2R59_001758"
     CDS             complement(53..787)
                     /locus_tag="U2R59_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEM8966146.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="U2R59_001759"
     CDS             1115..1525
                     /locus_tag="U2R59_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HEM8966147.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="U2R59_001760"
     CDS             1518..2219
                     /locus_tag="U2R59_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HEM8966148.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="U2R59_001761"
     CDS             2219..3805
                     /locus_tag="U2R59_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966149.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="U2R59_001762"
     CDS             3824..4045
                     /locus_tag="U2R59_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEM8966150.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="U2R59_001763"
     CDS             4042..4803
                     /locus_tag="U2R59_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEM8966151.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="U2R59_001764"
     CDS             5183..5692
                     /locus_tag="U2R59_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEM8966152.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="U2R59_001765"
     CDS             complement(5767..6306)
                     /locus_tag="U2R59_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEM8966153.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="U2R59_001766"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="U2R59_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEM8966154.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="U2R59_001767"
     CDS             7319..8170
                     /locus_tag="U2R59_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEM8966155.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="U2R59_001768"
     CDS             8198..8833
                     /locus_tag="U2R59_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEM8966156.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="U2R59_001769"
     CDS             8853..9626
                     /locus_tag="U2R59_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8966157.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="U2R59_001770"
     CDS             10034..10831
                     /locus_tag="U2R59_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HEM8966158.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="U2R59_001771"
     CDS             10809..11222
                     /locus_tag="U2R59_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEM8966159.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="U2R59_001772"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="U2R59_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEM8966160.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="U2R59_001773"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="U2R59_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEM8966161.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /gene="maf"
                     /locus_tag="U2R59_001774"
     CDS             15999..16559
                     /gene="maf"
                     /locus_tag="U2R59_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HEM8966162.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="U2R59_001775"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="U2R59_001775"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEM8966163.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="U2R59_001776"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="U2R59_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEM8966164.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="U2R59_001777"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="U2R59_001777"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEM8966165.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="U2R59_001778"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="U2R59_001778"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEM8966166.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="U2R59_001779"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="U2R59_001779"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEM8966167.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="U2R59_001780"
     CDS             21906..22484
                     /locus_tag="U2R59_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8966168.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="U2R59_001781"
     CDS             22536..23018
                     /locus_tag="U2R59_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEM8966169.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="U2R59_001782"
     CDS             23135..23509
                     /locus_tag="U2R59_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966170.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6646 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtt
//
LOCUS       DASHXG010000037        22822 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.037, whole genome shotgun sequence.
ACCESSION   DASHXG010000037 DASHXG010000000
VERSION     DASHXG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.037"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            255..740
                     /locus_tag="U2R59_001783"
     CDS             255..740
                     /locus_tag="U2R59_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HEM8966171.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            733..1416
                     /locus_tag="U2R59_001784"
     CDS             733..1416
                     /locus_tag="U2R59_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEM8966172.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            1542..4187
                     /gene="polA"
                     /locus_tag="U2R59_001785"
     CDS             1542..4187
                     /gene="polA"
                     /locus_tag="U2R59_001785"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEM8966173.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            4232..5068
                     /gene="mutM"
                     /locus_tag="U2R59_001786"
     CDS             4232..5068
                     /gene="mutM"
                     /locus_tag="U2R59_001786"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEM8966174.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            5032..5661
                     /locus_tag="U2R59_001787"
     CDS             5032..5661
                     /locus_tag="U2R59_001787"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEM8966175.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            5713..6045
                     /locus_tag="U2R59_001788"
     CDS             5713..6045
                     /locus_tag="U2R59_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEM8966176.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            6357..6848
                     /gene="nrdR"
                     /locus_tag="U2R59_001789"
     CDS             6357..6848
                     /gene="nrdR"
                     /locus_tag="U2R59_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEM8966177.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            6871..8244
                     /locus_tag="U2R59_001790"
     CDS             6871..8244
                     /locus_tag="U2R59_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEM8966178.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            8244..9170
                     /gene="dnaI"
                     /locus_tag="U2R59_001791"
     CDS             8244..9170
                     /gene="dnaI"
                     /locus_tag="U2R59_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEM8966179.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            9299..9739
                     /locus_tag="U2R59_001792"
     CDS             9299..9739
                     /locus_tag="U2R59_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEM8966180.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            9883..10584
                     /locus_tag="U2R59_001793"
     CDS             9883..10584
                     /locus_tag="U2R59_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEM8966181.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            10581..11702
                     /locus_tag="U2R59_001794"
     CDS             10581..11702
                     /locus_tag="U2R59_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEM8966182.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            11717..12949
                     /gene="pepT"
                     /locus_tag="U2R59_001795"
     CDS             11717..12949
                     /gene="pepT"
                     /locus_tag="U2R59_001795"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEM8966183.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            13081..13989
                     /locus_tag="U2R59_001796"
     CDS             13081..13989
                     /locus_tag="U2R59_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HEM8966184.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            14024..14296
                     /locus_tag="U2R59_001797"
     CDS             14024..14296
                     /locus_tag="U2R59_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEM8966185.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            14307..15353
                     /locus_tag="U2R59_001798"
     CDS             14307..15353
                     /locus_tag="U2R59_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HEM8966186.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            15604..18213
                     /gene="clpB"
                     /locus_tag="U2R59_001799"
     CDS             15604..18213
                     /gene="clpB"
                     /locus_tag="U2R59_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HEM8966187.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(18364..19050)
                     /locus_tag="U2R59_001800"
     CDS             complement(18364..19050)
                     /locus_tag="U2R59_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966188.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(19028..19522)
                     /locus_tag="U2R59_001801"
     CDS             complement(19028..19522)
                     /locus_tag="U2R59_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HEM8966189.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(19542..20762)
                     /locus_tag="U2R59_001802"
     CDS             complement(19542..20762)
                     /locus_tag="U2R59_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966190.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            20909..22744
                     /gene="lepA"
                     /locus_tag="U2R59_001803"
     CDS             20909..22744
                     /gene="lepA"
                     /locus_tag="U2R59_001803"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEM8966191.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT         7642 a         4100 c         4887 g         6193 t
ORIGIN      
        1 tcttgccaag cccccttttt tgcaacttat gataaacggt gttcaaaagc ttgcatctgc
       61 ggtaataagc ccaatcaaat caaaaacatg agaagctgtt ttttcttggc tgttcttatt
      121 atttgatgca ggacagcttt ttcacgacct ctgtaaacta taggaatctg ttaaatcaag
      181 ggagcagaac ttgcctttta cgctactttt ggtacaataa tgtatgatta aaaataaact
      241 ggagggtttc tatcttgaac ataggtaagc cgagaaaact aggaaaaaca ataaatgaaa
      301 tcgaggaagg cgactcgtta tccttaacag aatctattga agataaccag cttttgctgt
      361 atttgggatt gacgaatgat gcaaatcctt tgtatatcca acatgacttt gcacaaaaaa
      421 cagaatatca acagccaatc gttccatcag tgatgctgat ggggatcatc acaagtgcaa
      481 tttcaaagca tcttcctgga ccaggatcac atgttgtcaa tttttctgtc aattttattg
      541 aaccggtttt ccattatgaa acactgactt ttcagtttga ggtcataaaa gtagataaga
      601 tgaaggatgt ggtgacgatt tctgtagaag cggagaatac gaacgaagat cgtgtgttgg
      661 atgctgtcgt tatggtccaa ccgccacaag ttcctgaatt ggaaatagca atcgaaagtg
      721 aaggtgaatt gaatgaataa tccaagtaca tcaatgtcag gtatcaatcg tttttatgca
      781 aaagtttatg gatttttagg tatgggactt gcccttagtg cagtcacttc ttacttggct
      841 ctttgggtat ttcctttgca attagcaact tttatcaata attttccact aggctttgtg
      901 ggtctgtgga tcgttgaact gattttagta atggttctag gcgtaaaagc acaaaagaat
      961 ccgagcttag caatcggtgg atttattgcc tactctcttt tgaatggcat aacattagcg
     1021 gttactcttg catactacga tattggaaca gtaacgcaag ctttcttgac agctactttg
     1081 atgttcatgg ggatgtctgt tgtcggagta acaacaaaaa gagatcttag cggggttgga
     1141 agagcaggac aggcagcttt aatcggagtg atcattgcac tagtcttgaa catcttcatt
     1201 ttgagaagta gcgtagttga gctgttcatc tccctactgt tagtcgtcat ctttgcaggg
     1261 attacagctt atgataacca aagcatccgt aatatctatg tccagacaaa cggaacagca
     1321 catagtggaa ttgctgtatt catggcattg aagctgtatt tggactttat caacttgttc
     1381 ttggcgtttc tgagaatctt tggacggaac aactaaaaaa gaaaaaaatt catcagttgg
     1441 ggctataccg aattatttgg tatggtcccg ctttttcttt tcgcattccg caggattctt
     1501 tgttagaatg aataagaact ttacagtaag gagttaagaa gatgacaaaa aataaattat
     1561 tactcgttga tgggaacagt gtggcttttc gcgcattctt tgcgcttcac aattctcttg
     1621 aacgtttcaa aaatagaaac ggtcttcata caaatgcaat ctatgcattc aatacgatgt
     1681 ttgaaaatgt tatgcaaaaa gagcaaccga ctcatgttct ggttgcgttc gatgcaggaa
     1741 aaacgacttt tcggacagaa atgtatgcgg agtacaaagg tggaagatcc aaaacacctg
     1801 gcgaattcaa agaacaaatg ccatatatac gtgatttgtt gacaggacta ggggtacagt
     1861 attacgaatt gcccaattat gaagcagatg atattatcgg tactttggca gaaaaagtag
     1921 acaaagatca atttgatgtc gtcgtgcttt caggtgatcg ggatttgact caattagcta
     1981 gtaaagaagt aaaagtggat atcactgtaa aaggtgtcag cgatatcgaa agctatacac
     2041 cagaacatgt agcggaaaaa tatgatgggt tgacgccaaa acagattatt gacatgaagg
     2101 gactagccgg agatgcctct gacaatatcc ccggtgtgac taaaatcggt gaaaaaacag
     2161 ctatcaagct attgaaacaa tatggctcag tcgaaggaat ttatgaacat atcgatgaaa
     2221 tgaagcaaag caaaatgaaa gaaaatctga taaatgacaa agagcaggct ttcttatcga
     2281 aaaaattggc gaccatcaat acttcagcgc ctgtggatgt ctctatcgac tcattgaagt
     2341 atgaagggaa aaatctcgat aaactcgttc cgttttataa agaaatggat ttcaatcagt
     2401 tcctttctaa attgaatatc gtagaagaag aagtaaaaat ggatgatatt ttgtttgaag
     2461 tcgttcatga attcaaagag gaaatgttta ctacggatat ggcgttgtac gtggaaatga
     2521 tgggcgacaa ttatcataca gaggaaatcg tcggagtagc gtgggggaca gaaaagaaaa
     2581 tttatgtcac gaacgatcta tctgtattcg aaaaccgagc gttccattct tggatcactg
     2641 atccgactcg gctgaaaaaa gtatatgatg cgaaacgaac ttatgttgct ttaaaccgct
     2701 atactggaaa aacgaaagga atcgattttg atgtcttgct aggtgcatac cttctcgata
     2761 cgaatgaaaa aagcacagat atcgaaggaa tagctgctca ttacggatac aacgatatcc
     2821 aatcagatga agctgtatac ggcaaagggg cgaaaaaagg tttaccagaa gaagaggaac
     2881 tcttttttgc tcatttagcg cgaaaagtag ctgcaatcaa tgcgttgaca ccaaaattga
     2941 gccaagaact ggcagaaaaa aaccaagaag atcttttccg gaaaatggaa ctgccattgt
     3001 ctatcatttt ggcagagatg gaaataagcg ggatcaaagt agatgcgact cgcttacaag
     3061 aaatgaaggg cgagttctct gctcgcttaa gagagatcga acaaaaaatc tacgaagaag
     3121 ccggcgaaga attcaatttg aattcaccaa agcaattagg agtgatctta tttgaaaaaa
     3181 tgggattacc cgttatcaaa aaaacaaaaa ctggatattc cacagccgta gatgtactgg
     3241 aacagcttcg tgaacaagca ccaatcgtag aggatatcct cacctatcgt caaattgcaa
     3301 aaattcaatc tacctatgtc gagggactgc tgaaagtgat ccaatcagat ggaaaagtgc
     3361 atacccgtta tgtccagaca ttgacccaaa caggacgatt aagctctgtt gatcctaatt
     3421 tgcagaacat cccgattcga ttagatgaag ggagaaagat acgtcaggca tttgttccta
     3481 gagaaaaaga ctggctgatt tattcttctg actattcaca aatcgagtta cgcgtacttg
     3541 cgcatatctc aaatgatgaa catttgaaag ctgccttcct agaaggtcaa gatatccatg
     3601 ccagcacagc gatgcgtgta tttggaatcg aaaaggcaga ggatgtcaca ccaaatatgc
     3661 gtaggcaggc aaaagcagtg aattttggta tcgtgtatgg catctctgat tacggacttt
     3721 cacaaaatct aggaatcagc cgaaaagcag cacagcaata catcgatacg tactttgaaa
     3781 aatacccagg tgtcaaagaa tatatggaaa gaatcgtacg cgaagcaaaa gaccaaggct
     3841 acgtcgaaac gctgtatcac cgccgtcgat atctgccaga catcaattca agaaattaca
     3901 atatccgttc ttttgcggaa cgaacagcta tcaatacacc aatccaagga agtgctgctg
     3961 atattttgaa aatcgcgatg atcgaattgg ataaacgatt aaaagaaaca ggtcttcaag
     4021 ctacgatgct gttacaagtt catgatgaac ttgtcttcga ggtaccggaa aaagaacttg
     4081 aatcattaga taaattggtg aaggaagtta tggaacaagc tgtttctctt catgtaccac
     4141 tgatcactga cagcagttgg ggaaaaacgt ggtacgaagc aaaataaaca ttgtttaaga
     4201 cagagcaata taatgaaggt gaaaagaaaa aatgccagaa ttaccagaag tagaaaccgt
     4261 tcgtaaagga ttggaacggt tagtagtagg aaaaacgatt caaaaagttc aggtcttgtg
     4321 gcccaagatc atcgagcaac cagagacacc catctttgag gcttctcttg ttggcgaaac
     4381 catccaatcc attggacgta gagggaagtt tttaattttt catctcgatc attgtgaact
     4441 gatctcacac ttgcgaatgg aaggaaaata tcaatttacg aaagaaaata caccaatcga
     4501 taaacatacg catgtacttt tcttttttga ggatggaagc caacttcgct acaacgatgt
     4561 acgaaaattt ggtcgtatga caatcgtcga aaaaggagca agtgcaactt accgaggaat
     4621 catgaaattg ggacctgagc ctttgccaga tagcttctta ttagcagatt tcgcaaatgg
     4681 actgaaaaag tcccacaaag caatcaagcc attgctgcta gaccaacgtc tagtgactgg
     4741 tctaggtaat atttatgtag atgaagcatt atgggaagcg aagatccatc cagaacaacc
     4801 ggcgaacaca ctgcgcccca aagaggtaga acaattacgt ctatcgatca ttgatgtttt
     4861 ggatcgtgca atagaagccg gaggtaccac gattcgcagt tatttgaatg cattaggaga
     4921 atcaggcgga tttcaagtag cactgcatgt ctatcagcaa actggcaaac catgtatacg
     4981 ttgtggaacg ccgatcgtga aaacaaaagt ggcacaaagg gggacgcact attgtccgaa
     5041 ttgtcaaagg ctaaaaatcg caaagtagga tttgttttag gtttgacggg tggaatagct
     5101 accggtaaaa gtacggcagc caaagtcttt cagtctcatg gatttccttt gatcgatggc
     5161 gatgtgattg ccagagaaac tgttgagcct ggaacgcttg ctctgaggaa aattgtatca
     5221 gtgtttggcc aagaggtatt gcagcctgat gggcaactag atcgagggaa acttgggatg
     5281 attgtttttc catcaaagga aaaacggcaa aaacttgatc agctattaga tccgtttatc
     5341 cgaaaagcga taaaagatca aatcgcctct ctaagttcca atcatccttt agtaattgta
     5401 gatatcccat tgctctacga aggtcattat gaccactata tggatgcagt agctgtcgtt
     5461 tatactacgc cagaaactca gcttcagcgt ttgatgaaac gtaatcaact gacgctagaa
     5521 caagcgcagc agagaattag tagtcaactt ccaatcgaag aaaaaaagca gcgtgcggat
     5581 attttgttcg acaacaatgg aacaaaagaa aaacttgtgg gacaaatcga aaattggctt
     5641 tttgctaatc gctttctttg agtatctgtg tcaattttgc tatcctgagt atatagaaag
     5701 tgagggatag cgatgggatc attaaaaaat caaaaggata aagtcgtagg taacgcaaaa
     5761 gaaaaaatcg gcgagatgct caataaagaa aatctaatcg atgaaggtcg tacgcaatca
     5821 gaaacagcag aagaaaaaga aaagcagtac caagcaagaa tcgatgaaat agaagaccag
     5881 caggcagaag aagaagcgaa gcggcaagat ttgactcaag aacgaaaaaa tccgacacct
     5941 gatcgtagta aaacaccgct cccagaaagt gaccacattc ccgatgagca aaaaatcgag
     6001 gaacagcgaa tgaaacacta tacaggaatc gaagagaagt tataaaatag taaaaaatcg
     6061 agatgtgact tgaagcagat gagaaggtgt tcatctgctt caagtttttt gtgctagatg
     6121 actaaatcag cttttgtgta agttatttct cagtaatcaa ggtgatcagt attggaaaat
     6181 tgaaatttag taaggacagg ggacacaatt acgcatgaaa gtagaaaaaa ttgttcttat
     6241 atccgtgttt tttgggtagg acagtcgcgt ttgtgatttg tttcgtgtta taatacaact
     6301 agttgtaaag aaagacacat cctttatata aaatgcgatg caagaggtga gacaaaatga
     6361 gatgtcccag atgtcaacat aataattcac gagtaatcga cagccgtcaa gcagatgatg
     6421 gacgtgcgat ccgtcgccgt cgcgaatgtg agaattgttc gttccgattc actacatttg
     6481 aacgaattga agctgctccg ttattagtaa tcaagaaaaa cggggaacgc gaagagttca
     6541 atcgcgataa aattttaaga ggactcatcc gttcagcaga aaaaagacct gtagctatgg
     6601 aacaaatgga acaaatcgtc aaccatgtcg aaaaccgcgt acgcagtctc ggagaaaacg
     6661 aagtatcgac gaatctaatt ggtgaatatg tgatggaaga tttagttgat ttagacgaaa
     6721 tcgcttatat tcgttttgca agtgtttatc gccagttcaa agatatgtct gttttcttaa
     6781 aagagttgca agatatcgtg gataaagcaa aagaaaataa taaagagaat aataaagaaa
     6841 acaattaaga aacaaaaagg aggcatttcc ttggaaaatg cttggaaaga gcttcaacca
     6901 aaaaatattt accaaggaag aaaagcggct ccgctgagag aagacagcaa gaacgccttg
     6961 ctgtatcttt atcagccact aatcggcgga gaagccttga gtatctattt caccctgtta
     7021 tcagaaatct ctcaagaatc tggcaaaggt cctgaaggga tgcatgcaga tctgcttagt
     7081 agtctaggct gcggtatccc gcaattttat gatgcaagaa aaaagctaga aggaatcggc
     7141 ttactggatg tttattttaa agaagatagt gatctgggac ctcgttttat ttatgagctg
     7201 ttagaaccac tcattcctaa agcatttttc aaagactctg ttctggcttt tcttcttctg
     7261 gaaaaagttg gtgaacgacg attccagaag cttacccaat tctttgaacc taaaaggcat
     7321 acagcagagg gatatcaaaa aatcacaaaa aaatttttag atgtttatcg cttcaatgaa
     7381 gcagtgtacg ctgctaatca agaaaacatc gaatcgctga ataaatcttt tgaagaatct
     7441 gaatcagtag cattacttga agcagattcg acattcgatt ggcagttttt gaatgattgg
     7501 ctggcaaaaa aacatattgc aagtcttgat gatccaatca tcaaacaagt cgacatgtat
     7561 catcagcttt acggtttcga tgaattgaca cttggcgaac tgatcagtca atcttatgac
     7621 tttagtgaac aaaaagtatc tgaaaaagaa ctgcaaaaag ccattttggc aatgcagaga
     7681 cgtccggtga agcaaacaaa agaaacagtt gcggtttctg aaaacagtaa tgaaccctcg
     7741 tcaaacgaac atttgacaaa cgcagcgctt cagctgataa aagaagcaca gagcattcca
     7801 ccgatgaaat atctggaagc aatcaagtca gaaaaaggcg gatatgtttc taaacaagaa
     7861 aactggttac tgcaagatct tgtttctcaa tcaggtcttt ccagtagcgt gatcaatgtt
     7921 ttgctgaatt atgtactagt gatcaagaat aatgctagct taaatgccag ttatgtaaat
     7981 acagtggcaa atgaatgggc acaaaagaaa atcgccacag cagaagaagc gatccagcac
     8041 attcggcaaa taagtaatca agcaaaacaa tcaaaacaaa agaagcaaac aaattatcaa
     8101 actggcaagc gaaatgttcg acgggaaaag cttcctgatt gggtcaacca gccaaaagat
     8161 gaaaaacaga tcagcagcga gaaaaaagca gagattgacc gccgttttaa agaatacctg
     8221 gcaaaaaagg agggtgatat ctagtggaag acgtaggcaa agaattgaag aggatcatca
     8281 gcaaacgcaa ttatcaagaa aagtatgctg aaatgatcgc tgaagtctta aatgatgcgg
     8341 atgttcaagc ttttctaagc gcacaccaag aagaattgac acaagcggat attgaaaaaa
     8401 gttacgctaa attgtatgaa ttcgtgcaag aaaagcgtaa atatcaaaaa aacgatccaa
     8461 cgatgatcgc tcccggctat gagccgaagc tgacgttgaa ttttcattat gtggatgtca
     8521 cttatgtacc aacggaagca ttgttagcac ggcaaagaca agaagaaatc agaagccgag
     8581 taaaagcaat ggatatgcca aaagatattc aatcggcttc ttttgaaaac tttgaacgta
     8641 cagatggacg aggatatgcg agcttagaag ccctagattt tgtagagaaa tatactgctg
     8701 atccaaaagg gtatcataaa ggactgtatc tagtaggaag ttttggtatt ggaaaaacat
     8761 atttattagg agcaacagcg agagaattag cgattgctgg attcaccacg acgctagtcc
     8821 attttccgac atttgccgtt gagatgaaac aggcaatcgg aaaagatcaa gtggcagaaa
     8881 agttagatgc agtgaaacgt tcacctattt tgatgatcga tgacattggt gcagatgcga
     8941 tgagtagttg gatacgagac gaagtattcg gtgttatcct tcaatatcgg atgcaggaac
     9001 agttaccaac cttcttctca tcgaatttta caatggatga attggaacag catttgtccg
     9061 tcactcaacg tggagatgaa gagccgctaa aagcgaaacg gataatggaa cgcatacgtt
     9121 atttgacaaa agaaatcgaa atgactggtc gcaaccgacg caatggttga acagttgaca
     9181 agtccaactg acatttgacc tagtagtaaa agcaggtcag cgaatcatta tatggacaga
     9241 aatgaccgga gacaatcacc gcaacaagta atgcagaaac ttaaacggag gattttttat
     9301 gagggctatt ttttctagta tatctgtagt tggtctattt tttcttttag caggctgcgg
     9361 tagcgcagat agcaacacag gttctgttga ttcgattgat gcgggtcaaa cagtaaaaac
     9421 aagcagtacg aaaacggaga gacaaagcat atttgtcgga acgattgaaa gtatcactca
     9481 agtagaagca gaagaagaaa cgcttcagtt gaaactcgtc gatgtcatgg ccaaagaaga
     9541 tccagcgaat atgggaacgt cattcagcaa tgacggagtg atcttaaatg ctactgctga
     9601 aaaaataagc gtggacataa atgaattgaa aatcggtgac aaagtccaat ttacattagt
     9661 tgagatgccg atcatgacga tgtctatccc accgcaagtt cctggagatt cgattattga
     9721 tgtttcattg aacaaataac caataacatt ttttcaaaaa taagaaaatg ttgttttata
     9781 gaacgaaaag gtatattttt taaggagata tgggaatttt tttattccta gtctccttat
     9841 tttatttgga aaatgctata attatctaga aggagtgaag ctatgaacca tttagattta
     9901 tctcagcgct tagccgcagt gggtgacttt gtccctgaat ccgctcgttt agcagacatt
     9961 ggatcagatc acgcttactt acccgttgca ttgatattaa gaggaaaaat cgaatatgca
    10021 gttgctggtg aagtcgttca aggtccttat gaatcagcac gtaagcaagt caaaaaagat
    10081 ggattagaag accgtatcac cgtacgcctt gcaaatggtc tagatgctat ccagccacaa
    10141 gatggtatta cagctgtcac gattgcgggt atgggaggtt cactgatccg agatatccta
    10201 gaagctggca agttgaatca acgcttaagc ggacaagaac gtttgatcct tcagccaaac
    10261 atcggagagc gtacattacg atcttggctg caagaaaatc agtataaaat ccaatcagaa
    10321 aaaatacttg aagaaaataa aaaaatatat gaaatcattg tagccgaaaa agaacaaaaa
    10381 ccagttactt acaatgaaat ggagctgatg ttcgggccat ttctgcttga agagaaaagt
    10441 gagatcttca aatcaaaatg gacaagagag cttcaacaaa gaaaagctat ccgtgaacag
    10501 ctcaaacaag cagctaatca agaggcacgt caaaaacaaa tcgagcagga aatccaaatg
    10561 attgaggagg ttttaaagcc atgacaatca gcggacgcac tttcatccaa aagtttgaaa
    10621 gctattgtcc tcagtggcta gctgaagaag gagacccagt cggactgcat atcggaacat
    10681 tggataagcc aatccaacga gtaatgatga cattagacgt tcgtccagaa gtggtcgaag
    10741 aagcaatcaa gaaaaaaatc gatttgctga ttgctaaaca tcctccaatc tttcgtcctg
    10801 taaaacggct ggttactgat cagccacaag aaaaaatgta tgcagatttg ttgaaacatg
    10861 atattgccgt ctatgcagca cacacgaaca tggatattat ttgggatgga ctgaatgact
    10921 ggttttgtga acttctcggt attgaagtgg agagttattt agtaaagact catgagattc
    10981 attataaaaa actggccgtt tatgtacctg tggatcatgc acagaaaatg cgtgaagtat
    11041 tagctgcagc tggtgctggt acacaaggtg attataccgg tacaagtttt acctcgattg
    11101 gacacggtcg atttactccg gaagctggtg cacaaccagc gattgggaaa gtagggaaga
    11161 cagaacaagt tcaagaggca aaagttgagg ttattttgcc ggaaactatc gaaaaacaag
    11221 tgattcaagc catgcggtca gctcatcctt atgaggaacc tgcttatgat cttttcgcta
    11281 tagatgaacc agtcgaaatg tttgggttag gacgagtagg tgaattgccg caagaaattt
    11341 ctatagaggc atttgtagaa caagtaaaag aagcgttcca actagatgga ctgagaatag
    11401 tccagccaaa aaatgcaaaa tcctctgtga agcgcattgc gatttgcggt ggaagcggtg
    11461 aaaaatttta tccgcaagca atcgcccaaa gagcagatgt ctatatcacg ggagatatct
    11521 attatcatac ggctcatgat atgcaaagcg ctgggttgat tgcaattgat cccggtcatt
    11581 atattgaatc gttatgcaag caacgattta tcgagaaatt tgaatcttgg aaacaagaag
    11641 aaaattggga tattaacttt ttcgtttctg aaacaaatac aaacccattt caatttaatt
    11701 aaaaggagag aatactatgt acgaaaatct tttgccacgt tttttacgat atgtcaaaac
    11761 agaaacacgc tccgatgcaa caagcaaaac gactccatcg actcagacac aagttgcttt
    11821 tgcgcaagaa ttgaaaaaag aattagaaga gttaggctta gctgatgttt tctataatga
    11881 agataacgga ttcgttatgg gaacattacc aagcaatgtt gatcatgaag tgcgttccat
    11941 tggatttatt tcccacatgg atacagcaga ttttaatgca gtaggagtca atccacaaat
    12001 cattgaaaac tatgatggcg agtctacgat cgtactagat gcggaagaac gctatacatt
    12061 gaatacaaaa gattttccaa atttgaaaaa ttatgaaggc cacacattga tcacaacaga
    12121 tggcagtaca ttactgggag cagatgacaa atcagggatt gcggaaatca tgactgcaat
    12181 ggagatcttg atcaataatc cttctatccc tcacggtacc atcaaagtgg cttttggtcc
    12241 tgatgaagaa atcggtgtcg gagcggataa attcgatgtt gagcaattcg atgtagattt
    12301 tgcttataca gtcgatggtg gtcctttagg tgagttgcag tatgaaacgt ttagtgctgc
    12361 tcaagcaaat attacgatcc aagggaaaaa tgtacatcca gggacggcaa aagatacaat
    12421 gatcaatgct ctacagttag caatcgattt tcataatcag cttccagccg atgaagttcc
    12481 agaaaaaacg gaaggatacg aaggtttctt ccatttgatg gcattggatg ggaatcctga
    12541 agaagcttct atgagttata tcattcgcga tcatgatcgt gaaaaattcg aagcacgcaa
    12601 agcacaaatc acacatatcc aagaagagtt gaatcagcga tttgatcaag aacgaatcaa
    12661 agtagatatg tatgatcaat attacaacat gaaagaaatc attgaaaaag atatgagcat
    12721 cgtggaatta gcgaaacaag caatgatcga gcttggtatc tctccagtga tcgaaccagt
    12781 tcgtggagga acagatggtt caaaaatctc ttacatgggt attccgacgc caaatctatt
    12841 tgccggagga gaaaatatgc acggacgatt cgaatttgtt tctttacaag taatggaaaa
    12901 agcaacagac gtgattgtaa aaattgcaga attgaacaca aagagttaaa atcgaaaaag
    12961 aacagcttat gacaaggcgt tcgtcccaat gatggaatgt catctgtcta aggctaaagg
    13021 gcaggacaat ggaattggtt gtcccgccct cttttttgaa gagtaaatag gaggtaaaga
    13081 atggaaaagc tgctagtttt ttataacaaa agttcaggga aagatgaggg tgagaaatta
    13141 gcacgctggt ttcaagatta tgtaaaagaa aagcagccag aattatatgt agaactagct
    13201 gaaactggcc catcgattga tgatgcggaa ttagtcaaga aagcagaagc catagaagct
    13261 gatactttag taattatagg tggagacggc acgattcatc atatcgtcca agcgttccaa
    13321 aaaacattat ctcaatacca tgtcggatta cttccaggtg gaactgtcaa caaccttgca
    13381 cgtgttcttg agattcccct caaaaaagaa gaagctgctg acgtgatcct ggaaggcaat
    13441 gtacggaaaa tagactatgg tcaagtcaat gatgaagtca ttatctctac actgacaatc
    13501 ggaatcttag cagatacagc agtttggatc agtcaagaag aaaaacagcg ttacggctcg
    13561 tggatcttta tcaagaagtt ttttaagtta ttgctgaaga agaaaaaata tcatttggat
    13621 ttagaaacag acgaggagca ttggaaagga aaatcccaac tgttgacagt cacgatgtct
    13681 aactccgtgg gcggttttac aaattttgac gactcagcga ccctagatga tggaaaattt
    13741 catgtaacga tcgtaccttc cttagatatt ttccgattta ttttttattt gcctagaatc
    13801 atgagaggca aattctatac gatccccggc attacttatt tcacagccaa acgcatgaaa
    13861 atccaagcgc aggaaaaatc tgtgggcact cgaacggatg gagacacgac agatgatctt
    13921 ccagttgaat tatctgttgt atcaaaagga ttaacagttt attcaccaaa gaaagaagaa
    13981 aaagcttaga aatagtagtt aacagaaagt tggaagaaga gtaatggatg tattgttaca
    14041 caatcctttg tggttttacc ttttcattgt gaatttttac ttattttgtc tgatggggta
    14101 tgataaacat caggctagaa ctagcggctg gcgtgttcct gagaataatt tgatatttgt
    14161 cagcctgtta ggcggtggtt tgggaggatt gatctctcga aaagttttcc atcataaaac
    14221 tcggaaaaag aagtttacta taggattcgc tgcaggtgta cttgttgatt tgattctcat
    14281 ttattttttc cattaaggag caggagatgt cgtctaaagg aacgaaaact aaaatcattc
    14341 tgaatctgct tttgctgatt gtgatttttg ccattattta ttatttaatc aatcaatcat
    14401 ttgcagatat ctttgccgaa ttgctgtcta ccagtgttgt tgttttggca gcggctgtta
    14461 tattagggac agtttaccaa atcgctgaag ggcgctcaat caaagaaatt gctgaacctt
    14521 tcgcgccgaa ttttacaacg aaagatgggt tcttgacctc tagctatatt gcgttttacc
    14581 gaatcgtttc gtttggtaca ggaacgctga tctcggagat ttatttttat aacaaaaaag
    14641 gaatgaagct atcccaggga gcaggggtga cagcactcca tatgattatg tacaaactgg
    14701 cagtgatcac ttatgcatta gctggcttgg tcatccaatt ctctcttttt tattctaatg
    14761 gtccatcaat gatctggttt atcatcgctg gtatcctttt gacgatcgtg attgttgcct
    14821 ttttattggc gatgtccgtc agcttgaatg ttcaaatatt ttttgtcagc ttatcgaata
    14881 agttatttaa aagtgagcgt ttgcggaaat gggtggatac atgcaatcag cagatctact
    14941 ctttaaggga aacggtccaa accattatcc aagacaggac tgcgctattg cggatttatc
    15001 tatggaatat gttaaaactt gtattttggt atgtacttcc ttatttgatt ctgattgaaa
    15061 accatcctaa aatagatttt ctactgacca tttcgtttat cagctttgca gtagtgcttt
    15121 caggggttat tcctacgcct gctggtattg gttcctttga atttgtctat ttgttattat
    15181 tcagaccagt tgttggaaca gttgacgcag tttcttcgct tttactgtat cgtttcagtt
    15241 cctttatctt gccatttctc tatggatttg tgtatgtgat tgctgaacgg cgaagagtga
    15301 tcaaagaaga aataatagaa gtaaaaaaag agaataaaga aaatcaaggg taggtctttt
    15361 ataagatcta ccctttttat caaatcaaag aaaaacgtta tggataagat aattttacgt
    15421 ttgtttggct ctttttttat atacatacaa tcaattttgt ttttttaaga tttatataag
    15481 tcgagaaaaa aagtcaaaaa actatgtgta tattttgacc aaaattgacc aaagcgatat
    15541 aatagttttt gtaaagatca aagaaataag tgatcttacc tttaattagg agggtatacc
    15601 tgtatgaata ttgagaaaat gactacgacg cttcaagaag cgattgctga agctcaacag
    15661 attgcggtca ctcgaaaaca tcaagatatc gacattgccc atgtatggaa aatcttttta
    15721 caatctaatc attttggtcg aaatttctat acggatgccg gattggatgt cgaatctttt
    15781 gaacatgaaa ttgatcgtct actggatgag tatccagttg tttctggtgg aaacgtccaa
    15841 tatggacaaa acctcagcca gaatttcttt cgattattga atgaagcaga ccaaatacgt
    15901 gaaagcttcg gcgacgagtt tctttcaacg gaagtcgtta ttttagcgtt gatgaaatta
    15961 aaaaattatc cgttaactgt ttatttgaat aaaaacggat tatctgaaaa agaattgcgt
    16021 aaaaacatcg aagagatgag aggaggagaa agagtgacct cacaaaacca agaagaacaa
    16081 tacaaagcat tagaaaaata cggcgttgat ttagtacagc aagtcaaaag cggaaaaatg
    16141 gatccaatca tcggtcgtga tgaagaaatc cgtgatgtca tccgtattct ttcacgaaaa
    16201 acaaaaaata atcctgttct gataggagaa cccggtgtag ggaaaacggc aatcgttgaa
    16261 gggcttgctc aacgtatcgt acgcaaagat gtgcctgaaa atttaaaaga taaaacgatt
    16321 ttttcattag atatgggtgc attgatcgct ggagcaaaat tccgtggtga atttgaagaa
    16381 agactaaaag cagtcttgaa agaagtcaaa aaaagtgatg gacgtatcct cttgttcatc
    16441 gatgaaatcc acaatatcgt aggggcagga aaaacagaag gaagtatgga tgccggaaat
    16501 ctgttgaaac caatgcttgc tcgcggtgaa ttacatttga tcggtgccac aactttagat
    16561 gagtaccgtc aatatatgga aaaagacaaa gcgttggaac gtcgctttca aaaggtatta
    16621 gtcaaagaac caacagtgga agatacgatc agtattctgc gtggattaaa agaacgtttt
    16681 gagatccacc atggtgttaa catccatgac aacgcattag tagcagcagc tactttatct
    16741 gaccgttata ttactgatcg gttcttaccg gacaaagcaa tcgatttgat cgatgaagcc
    16801 agtgcaacga ttcgggtaga aatgaactct atgccaacgg aattagatca agttactaga
    16861 cgtttgatgc agttggaaat cgaagaagct gcactgaaaa aagaatcaga tgatgcaagt
    16921 aaaaaacgct tgaaaaattt gcaagaagaa ttagctgaac ttcgtgaaga agcaaatgcg
    16981 atgaagatgc agtgggaaac agaaaaagaa gaagtcaatt ctgtttcagc aaaacgtgct
    17041 gaaatcgata aagcaaaaca cgaattagaa gatgcagaaa ataactatga tttagaacgc
    17101 gctgctgtat tgcgtcatgg tacgatacct caattagaaa aagaattgaa ggaattagaa
    17161 gctaaagcaa aagacagcga gattaagatg gttcaagagt ccgttaccga aaatgagatt
    17221 gctcaagtcg ttggcagatt aacgggtatc cccgtaacga aacttgtaga aggtgaacga
    17281 gaaaaactaa ttaaattgaa tgaaacactt cataaacgag tgattggtca agatgaagca
    17341 gttgatgcgg tcagtgacgc ggtaattcgt tcacgggctg gattgcaaga cccaaatcgt
    17401 cctctaggtt ctttcctttt cctaggacca actggtgtcg gaaaaaccga attagcgaaa
    17461 gcgttagctg agaacttgtt tgactcagaa gatcatatgg tacggatcga tatgagtgaa
    17521 tatatggaaa aacatgctgt gtctcgtcta gtcggagctc ctccaggcta tgtaggttac
    17581 gaagaaggtg gtcaattaac ggaagctgtc agacgaaatc cttatacaat cgtcttgttg
    17641 gatgaaatcg aaaaagcgca tcccgatgtc ttcaatatct tgttacaagt cctagatgac
    17701 ggacgcttga ctgattcaaa agggcgagta gtagatttca aaaatacggt tctgatcatg
    17761 accagcaata tcggttcaca gttactgctg gaaggcgtga ctgctgatgg aacgattcca
    17821 gaagcagtgg ctgaacaagt caacacgcta ttacgtggaa acttcaaacc agaattcttg
    17881 aaccgaatcg acgacacgat tttatttaca ccattgagcc tagacaacgt gaaaggaatc
    17941 gttgacaaaa tggtggcgca attggcacaa cgtctggaac atcaagaaat cctgctgaca
    18001 atcagtgatg aagccaaaac gtggattgct gaaaatgctt atgaaccagc atatggtgca
    18061 agaccattga aacgatttat cactaaggaa gtagaaacac cactagctaa agaaatcgtt
    18121 gcaggacatg ttatgcctaa atcaaaagta acgattactt tacttgatgg acaacttcat
    18181 ttcaaaacag aagagctaga agaaatcgtc taatcttcca ttgagactat aaaagaaaaa
    18241 aggggtctga cacaactagt gtcagacctc cttttttcaa ataaacagtg ttccagaagt
    18301 agtttcttcg aaaaataagc cgaaatttct tgaagctgcc cgcttctgtc acaacctctt
    18361 ttattaggta tttttcactt tttctaattt ataactttca aagtaacgct catctttttt
    18421 actttgagac catgcaaaca atcccattaa ggcagcacct atcgtatttg tcagcaagtc
    18481 gcccatcgta tccatcaatg ctgctcgtcc gacaaacagt gtgccatcag aagcagcaaa
    18541 acgttgaaga ttcatgccta agaactggtc gcataagaat tcccagaact cccaaaacac
    18601 gccgcaaagt ccagcaaacg caaagccgaa taagaggaac aaccaaggac tggtttttga
    18661 tatctcagca tctttcatca agtaaccaat caatccatag ccaagagctg tcaggaccat
    18721 tggactcacc gcatgtaaga ttttgtccca aaaagagatg atactgatca aatgcatccc
    18781 tgtgcctaaa aagacagaga tgaacaagaa aaaccagtaa aacaaaacga ttgctgctgg
    18841 tattttaagt ttgaaaactt tcaaaatgac ttgtggcatg aaaatcaatg caatccctaa
    18901 taaagattcc acgataaatg tgattccttg agaagtcgaa tatttttgtg tgataaattc
    18961 ataaaaatta tagcagacaa cgaatacacc aaaagcaagt aaagctattt gcaccttttt
    19021 gatttcttta atcactgaaa gtccctccat ctaaaaatct ttttacttct gaaagcaact
    19081 caatttctga agaaaccact tttccgttca atttgatcaa acctattgta tataagttca
    19141 ggtagtgaaa ttgattttca gctgtttctt gtagtgcagc gatttttttc gggtgggttc
    19201 cgccttgctg tcgagtatca gtatataagc cgatcactgg gatgcctttc gcataagcca
    19261 caccgatttc cgatgctacc ccggcatcga tcgtcagccc atctagtaaa gcaatcatta
    19321 aatcactagc caacactttt tctgtgtcag caagagcaat cattcgactg tctgcataag
    19381 cagttttgtc attgattgct tcattttctt gaggaagata gatcgaaagc tcagaagaga
    19441 gctctctgat ttctttaact aactgttggt tatataacaa atcactttta gcaaacattg
    19501 gtgcggcaaa ataaattttc atctaaacat catccttttt atcaaaaata atcgctaaag
    19561 taagcttcca tgtttggaat gatacgctct agtgacttca gtgtttcttc atctgtttct
    19621 aaccgttcga ttcttgccaa ataagaagca cggcgataat tcatcatcaa gcaagtcaat
    19681 gtttggatat ccagtcgaac ggattttcct ataggttcat ttaagacacg gacttgtccc
    19741 tgttcatccc atgttaaagc gaagacacca ttattccaag gagcgacagg atcttcaatg
    19801 atgaaatgaa aagcatcagc tgttccaaca aacggaaacc gttgaaggaa ttcttttaca
    19861 tcaacgatcc gagccataaa atatggttcg atctgctctt tgatctgact atcttcaatc
    19921 aaaaatgcta aaggctcatt tttataaata tctccatgta cccagtagat catggaaaaa
    19981 tgtgcggaaa taaagttcca taagccattt cgagcttctt gatcaagata gaacatttct
    20041 tttacgtgaa atatttcttc agctacccag tagaacagaa cacctcttgg ttcatggttg
    20101 ctatcgtagt agacagcggc tgtgcgctca tcttcatttt cgaaacgcca atactcttcc
    20161 caatgaaaat cactgcggaa taaagcacca tggttttgtt gggcaaattt gtcataaacg
    20221 gaaaatacgt ctggatgatc aactggtaat cgctcaacca taccacttac tgggatttgt
    20281 ttaggtagct gtgtatctct gattttaaag gaaagtttat cagacatgat ttcccatcct
    20341 ttacgccgat agtaggggat actgtaagga tacaaataag agatccattg cttattcttg
    20401 cgcatattat ccaatgcaac gataattaga tcttgcatca atccatggtt agcatattct
    20461 ggataagttc caactccagt cacaccaccc attttataac gtgcaccgtg aatattgact
    20521 tcacaaggat agatagcgat ttgagagatc agtttatttt cgtggaacca tccgaacact
    20581 ttcgatactt ccaaaatcgg ttttttggaa cggataaaag ctcgtttatt ctcaaacccg
    20641 ctttcctcga tgtctgcttc agtcacttgg aacacatagg aaagcaattc attgaattga
    20701 tcgatatgtt cttgagtgac cggttttaat tcaagatttt ctctaaaatc tttttgatcc
    20761 attttttcat ctccatttat tagcttgata acagtatagc aaaattctac aaaaaaaact
    20821 tctatagctg actaattaaa aactctttaa attactgctt ttcgttggta taatggaaag
    20881 tgctgattat atgaaaagag gagacgctat ggatataaag aaaatgaaag aacgccaaga
    20941 gcagattcgt aatttttcga tcatcgctca tatcgaccat gggaaatcta cattggccga
    21001 tcgtatttta gaaatgacgc acactgtgac gtctcgcgaa atgcaagatc agctgttaga
    21061 ctcgatggat ttggaacgtg aacgtggaat cacgattaaa ttaaatgctg tagaactcaa
    21121 ttacacagcg aaaaatggag aaacatatat ctttcacttg attgacaccc cagggcacgt
    21181 cgacttcacc tatgaagtct ctcgaagcct tgctgcctgt gagggtgccg ttttagtggt
    21241 cgatgcagca caaggaatcg aagcacaaac attggccaat gtttatttag cgttagacaa
    21301 tgatttggag atcctgccag tcatcaataa aatcgaccta cccgcagcag atcccgaacg
    21361 tgtccgtcaa gaaatcgaag acgtaatcgg aatcgatgct agtgaagctg tattagccag
    21421 tgccaaatca gggattggga ttgaagatat tctcgagcag atcgtggaat atgttcctgc
    21481 accaagtgga gacttagatg caccgctaaa agctttgatc tttgactcta tttatgatag
    21541 ttaccgcggt gttgttctaa atgtccggat cacggacggt atggtcaaac ccggagacaa
    21601 aatcaaactg atgagtaatg gcaaaacatt tgatgttaca gaggtcgggg tcttctcgcc
    21661 aaaagcagtt gctagagact ttttgatggt cggtgatgtc ggttatatca cagcaagtat
    21721 caaaactgtc caagatacac gagtagggga tacagtaacg ttagcagaca atcctgccgc
    21781 tgaagcttta ccaggttacc gaaaaatgaa tccgatggtt tattgtggtc tttatccaat
    21841 tgatacttct cgttacaacg atttgcggga agctttagaa aaactgcaat tgaatgatgc
    21901 tgctttacaa ttcgaaccag aaacctctca agcattaggt tttgggttcc gctgtggatt
    21961 cctcggactt cttcatatgg atgtcgtcca agaacgcttg gaacgggaat tcaatctaga
    22021 attgatcacg actgcaccat ccgttattta ccatgttaat aaaacggatg gtacgactgc
    22081 tacagtagat aacccggcag attttcctga acctgtaacg attcaggatg tagaagaacc
    22141 attcgtcaaa gcacagatca tggtcccaaa tgattttgtc ggtgcagtaa tggaactttc
    22201 tcaacgaaaa cggggagaat tcattacgat ggattattta gatgattacc gagtaaatgt
    22261 cgtctataat attccgcttt ctgaaattgt ctttgacttt ttcgacaaat tgaaatcaag
    22321 cacgaaaggc tatgcctcat tggattatga aatgtctggt tatcaaaaaa gcaagttagt
    22381 gaagatggac atcttgctga atggagaaaa agtcgatgca ttaagcttta tcgttcaccg
    22441 agactttgcc tatgaacgtg gaaaagcaat cgttgaaaaa ctgaaaaaac taatcccacg
    22501 ccaacaattt gaggtgccaa tccaagcagc tattggacaa aaaatcgttg cccgttcaga
    22561 catcaaagcc ttgcgtaaaa acgtcttggc taaatgttat ggtggagatg tttctcgtaa
    22621 acgtaaactc ttagagaaac aaaaagaagg gaagaagcgg atgaaacaaa tcggctccgt
    22681 cgaagttccg caagaagcct tcatggccgt tctgaaaatg gacgaggacg aaccgaagaa
    22741 atagcaaggg tttgtttgaa aacagtgtaa aaaataaacc atgtttacat ggatttgcca
    22801 ccggtttgcc accggtggtt tt
//
LOCUS       DASHXG010000038        22763 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.038, whole genome shotgun sequence.
ACCESSION   DASHXG010000038 DASHXG010000000
VERSION     DASHXG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.038"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..305
                     /locus_tag="U2R59_001804"
     CDS             6..305
                     /locus_tag="U2R59_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8966192.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="U2R59_001805"
     CDS             378..1739
                     /locus_tag="U2R59_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEM8966193.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="U2R59_001806"
     CDS             1761..2021
                     /locus_tag="U2R59_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966194.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="U2R59_001807"
     CDS             2035..2787
                     /locus_tag="U2R59_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEM8966195.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="U2R59_001808"
     CDS             complement(2881..3486)
                     /locus_tag="U2R59_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8966196.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="U2R59_001809"
     CDS             complement(3539..4513)
                     /locus_tag="U2R59_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HEM8966197.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="U2R59_001810"
     CDS             complement(4891..5610)
                     /locus_tag="U2R59_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966198.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="U2R59_001811"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="U2R59_001811"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEM8966199.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="U2R59_001812"
     CDS             7161..8558
                     /locus_tag="U2R59_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8966200.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="U2R59_001813"
     CDS             8639..9079
                     /locus_tag="U2R59_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8966201.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="U2R59_001814"
     CDS             9227..9553
                     /locus_tag="U2R59_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8966202.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="U2R59_001815"
     CDS             9554..10303
                     /locus_tag="U2R59_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966203.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="U2R59_001816"
     CDS             complement(10383..10838)
                     /locus_tag="U2R59_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEM8966204.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="U2R59_001817"
     CDS             complement(11265..11540)
                     /locus_tag="U2R59_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966205.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="U2R59_001818"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="U2R59_001818"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEM8966206.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="U2R59_001819"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="U2R59_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEM8966207.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="U2R59_001820"
     CDS             14770..17436
                     /locus_tag="U2R59_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8966208.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="U2R59_001821"
     CDS             17800..18552
                     /locus_tag="U2R59_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8966209.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="U2R59_001822"
     CDS             complement(18574..19728)
                     /locus_tag="U2R59_001822"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEM8966210.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="U2R59_001823"
     CDS             19913..22354
                     /locus_tag="U2R59_001823"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEM8966211.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22511..>22763)
                     /locus_tag="U2R59_001824"
     CDS             complement(22511..>22763)
                     /locus_tag="U2R59_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8966212.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         7291 a         3995 c         4749 g         6728 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcaatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttggctct tcgtcaaatt
    22441 gtgttggcga agacaaattt gaataaaact tagtccgata tgcggcgcgt tctgtgcgcc
    22501 gcatattttt ttagttttca aagatcagac cttgttgtaa atagatccgt gcccgaaagt
    22561 tataaaagtt gcgataacca aacgcaattc gtttaatcag cttgatcttg ttattcagcc
    22621 cctcagtgac gccgtttgag tggggcacct taaaggcatt tgaaataccc gattggtagc
    22681 gatggaagat cgtgaatttc tttttaaacg actgaggtaa cgtagatgaa attgttttaa
    22741 gggtttcttg aaagccttcc gta
//
LOCUS       DASHXG010000039        22226 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.039, whole genome shotgun sequence.
ACCESSION   DASHXG010000039 DASHXG010000000
VERSION     DASHXG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.039"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..496)
                     /locus_tag="U2R59_001825"
     CDS             complement(<1..496)
                     /locus_tag="U2R59_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8966213.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEF"
     gene            769..3240
                     /locus_tag="U2R59_001826"
     CDS             769..3240
                     /locus_tag="U2R59_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8966214.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3343..5079)
                     /locus_tag="U2R59_001827"
     CDS             complement(3343..5079)
                     /locus_tag="U2R59_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEM8966215.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5076..5780)
                     /locus_tag="U2R59_001828"
     CDS             complement(5076..5780)
                     /locus_tag="U2R59_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8966216.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5911..6414
                     /locus_tag="U2R59_001829"
     CDS             5911..6414
                     /locus_tag="U2R59_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HEM8966217.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6374..6712
                     /locus_tag="U2R59_001830"
     CDS             6374..6712
                     /locus_tag="U2R59_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEM8966218.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6733..8151
                     /gene="ffh"
                     /locus_tag="U2R59_001831"
     CDS             6733..8151
                     /gene="ffh"
                     /locus_tag="U2R59_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEM8966219.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8263..8841
                     /locus_tag="U2R59_001832"
     CDS             8263..8841
                     /locus_tag="U2R59_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEM8966220.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8845..9366
                     /locus_tag="U2R59_001833"
     CDS             8845..9366
                     /locus_tag="U2R59_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEM8966221.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9445..9999)
                     /locus_tag="U2R59_001834"
     CDS             complement(9445..9999)
                     /locus_tag="U2R59_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEM8966222.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPCGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10252..10527
                     /gene="rpsP"
                     /locus_tag="U2R59_001835"
     CDS             10252..10527
                     /gene="rpsP"
                     /locus_tag="U2R59_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEM8966223.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10539..10790
                     /locus_tag="U2R59_001836"
     CDS             10539..10790
                     /locus_tag="U2R59_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEM8966224.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10915..11706
                     /locus_tag="U2R59_001837"
     CDS             10915..11706
                     /locus_tag="U2R59_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966225.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11876..12397
                     /gene="rimM"
                     /locus_tag="U2R59_001838"
     CDS             11876..12397
                     /gene="rimM"
                     /locus_tag="U2R59_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEM8966226.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12387..13148
                     /gene="trmD"
                     /locus_tag="U2R59_001839"
     CDS             12387..13148
                     /gene="trmD"
                     /locus_tag="U2R59_001839"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEM8966227.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13284..13631
                     /gene="rplS"
                     /locus_tag="U2R59_001840"
     CDS             13284..13631
                     /gene="rplS"
                     /locus_tag="U2R59_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEM8966228.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13763..14899)
                     /locus_tag="U2R59_001841"
     CDS             complement(13763..14899)
                     /locus_tag="U2R59_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8966229.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPNLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKMPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVDFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPKGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(15016..15708)
                     /locus_tag="U2R59_001842"
     CDS             complement(15016..15708)
                     /locus_tag="U2R59_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966230.1"
                     /translation="MKKVILGLVFGAFFLTGCSQSNVVDNTGKTNEKDSSVTLSESTT
                     QSSKNSQEVDGPLLKVGQWTKEKRDTSGKIELIGTASPQSDIPLGDIGIYISNIKLLK
                     YSNYADPSAAGYYDANNHKDSEGNFYGLQIAFKVKNNSEVDYGYNGLAHAILDNGQQI
                     DFSSDDLMHTMTTNSFFKKTESKEFYSLAYLDPSKVNDITKVTIKTGVLYNPSDYSTV
                     AESAESTFNINR"
     gene            complement(15846..16499)
                     /locus_tag="U2R59_001843"
     CDS             complement(15846..16499)
                     /locus_tag="U2R59_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966231.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKVSKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     GQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(16549..16977)
                     /locus_tag="U2R59_001844"
     CDS             complement(16549..16977)
                     /locus_tag="U2R59_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8966232.1"
                     /translation="MEMDTINLVEELKRKYRSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIDELKNLYGLPESAYRFLI"
     gene            complement(16982..17356)
                     /locus_tag="U2R59_001845"
     CDS             complement(16982..17356)
                     /locus_tag="U2R59_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966233.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
     gene            17641..17826
                     /locus_tag="U2R59_001846"
     CDS             17641..17826
                     /locus_tag="U2R59_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966234.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            17839..18087
                     /locus_tag="U2R59_001847"
     CDS             17839..18087
                     /locus_tag="U2R59_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966235.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKITPKEFIEKHLVDL"
     gene            18118..18297
                     /locus_tag="U2R59_001848"
     CDS             18118..18297
                     /locus_tag="U2R59_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966236.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(18340..18810)
                     /locus_tag="U2R59_001849"
     CDS             complement(18340..18810)
                     /locus_tag="U2R59_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966237.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            18897..19595
                     /locus_tag="U2R59_001850"
     CDS             18897..19595
                     /locus_tag="U2R59_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HEM8966238.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            19773..20114
                     /locus_tag="U2R59_001851"
     CDS             19773..20114
                     /locus_tag="U2R59_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966239.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            20107..20777
                     /locus_tag="U2R59_001852"
                     /pseudo
     CDS             20107..20777
                     /locus_tag="U2R59_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
     gene            20783..21469
                     /locus_tag="U2R59_001853"
     CDS             20783..21469
                     /locus_tag="U2R59_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966240.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            21472..21699
                     /locus_tag="U2R59_001854"
     CDS             21472..21699
                     /locus_tag="U2R59_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966241.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            21717..22040
                     /locus_tag="U2R59_001855"
                     /pseudo
     CDS             21717..22040
                     /locus_tag="U2R59_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617897.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         7293 a         3881 c         4399 g         6653 t
ORIGIN      
        1 tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg taatgcttcg
       61 ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc ttagcgatta
      121 gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt tcctttgtta
      181 gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca caatcatggc
      241 agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact ttcaacatct
      301 gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag tgttcacaat
      361 aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct ttatattctt
      421 tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg agtaattttc
      481 tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc gactaaattt
      541 taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta gaaaatcgcc
      601 ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat atgacaggaa
      661 tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct atactggata
      721 ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat gaagaataaa
      781 tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa agtcatccgt
      841 ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg aatagaaaaa
      901 ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat cgtattggaa
      961 aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct ttgtttagta
     1021 gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg aatcgccatt
     1081 tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa tacagcaaaa
     1141 gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct tgtaatagat
     1201 gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt cgtggaaggg
     1261 aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac caaagaaata
     1321 ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc ccgattagac
     1381 aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac aatgggagaa
     1441 ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat tgggatcatc
     1501 attattccta tcggtatcct gcttttttct caaagttact tttttaatgg aaacacgatc
     1561 aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga aggactgtac
     1621 ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca aagagttctt
     1681 ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg tgtagataaa
     1741 acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc taaaaaacaa
     1801 gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc aaaagcgatg
     1861 gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac cactgatcaa
     1921 tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt agcgttggca
     1981 gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt gccggaatat
     2041 gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt tggtgtgtac
     2101 gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg ctatattctg
     2161 attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa aaaacagcaa
     2221 gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt agctgtccaa
     2281 gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga agaagaatat
     2341 gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca aaagaaaatc
     2401 ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg cgtgaatgat
     2461 attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa tgaagccgcc
     2521 atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc agaagttgtt
     2581 gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt tttagtgaag
     2641 aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac ctatccttta
     2701 gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc tttcttgctt
     2761 gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt gatggaaaaa
     2821 gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat ctgcggggtg
     2881 actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt gattgcagta
     2941 gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag tcagatcatt
     3001 cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct gttttcaatc
     3061 accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc ggcagattcg
     3121 atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa tgaaaaagag
     3181 caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg agaaaattga
     3241 cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt tcgaagcagg
     3301 atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt tcggaatggt
     3361 aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac cattaaggag
     3421 ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat gtcggcttcg
     3481 cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa tgtcgatacc
     3541 tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc ggataataat
     3601 ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga taattggata
     3661 aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa tcgtcaaccg
     3721 tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag gttctgtata
     3781 aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga tttcccgaat
     3841 cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag tcagagtttg
     3901 cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg aagtcacagg
     3961 agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt ctaaacgtcg
     4021 cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg aattagtaaa
     4081 gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct cctgatggat
     4141 cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct cttgaatgac
     4201 ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct gcatctttgg
     4261 attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa tcatcagttc
     4321 gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca tcttactcat
     4381 ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg gtgtttgcat
     4441 gattacttcc gcctgattag gattttgcac catttttttt agtacgggca gcacggtttt
     4501 caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa caaggaagaa
     4561 agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta aaaaaccgct
     4621 tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga ctggtaatgc
     4681 gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac ctaggttccc
     4741 accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca atgtttcatt
     4801 gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt cgttcgactg
     4861 atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt cgacatctaa
     4921 ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt ccacgatctg
     4981 ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa ctaaaagaat
     5041 aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc ctgaaactta
     5101 tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg ctcgattttt
     5161 tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa gtcaaaattc
     5221 caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt catgaaataa
     5281 acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac ggtcacttga
     5341 taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc agcttcatct
     5401 tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc taatacttcg
     5461 cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc aatgatccga
     5521 tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt ttcttgacgc
     5581 agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa aatgatgaaa
     5641 tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc actggttacc
     5701 ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg ttcatcatca
     5761 acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg tttatatttt
     5821 agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata ataggaaggc
     5881 actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg tttaggcggt
     5941 ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga actagttgaa
     6001 actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat tcctagagat
     6061 cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc aaaagtatgg
     6121 acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa agcctatcaa
     6181 aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc ttcatgcgga
     6241 acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc cggagtggct
     6301 actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg gctgaaaact
     6361 agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct ttgaatttta
     6421 ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg cagatgattt
     6481 ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat atgacaatat
     6541 caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt tttctaatta
     6601 tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata agtacccgga
     6661 agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat aaataaaagg
     6721 aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc gatgggaaaa
     6781 ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg ggaaatccgc
     6841 cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac taagcgcgta
     6901 cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca acaaatcgta
     6961 aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga gttaaataaa
     7021 tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg taaaacgacc
     7081 tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc gctcctaatc
     7141 gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg tcaacagcta
     7201 gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt ccgtcaaggg
     7261 atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc aggacgtctg
     7321 catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac gcaaccaaat
     7381 gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt agctgatagc
     7441 ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg ggatactcga
     7501 ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt catcggttct
     7561 ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag ccgtatcctt
     7621 ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga cgagaaaaaa
     7681 gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga ctttattgaa
     7741 cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat gatcccagga
     7801 atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt tgaacgcaaa
     7861 aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct gttgaaccca
     7921 agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt gaatcgaatg
     7981 atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg ggatatgaac
     8041 atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg caaaatggcg
     8101 atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata agatgaaaaa
     8161 aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca gcaattttta
     8221 ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg tccgtggagt
     8281 gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc tgaatatgat
     8341 gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt gagctggcag
     8401 acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga tatcaaaaaa
     8461 gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg aattattcgt
     8521 aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa aattcaagaa
     8581 gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat cgttgattct
     8641 tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga attagcaaaa
     8701 gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc ttttttagaa
     8761 gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga ggtcgtacgt
     8821 atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc tataagttta
     8881 gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac tccaacaggt
     8941 aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat gggcagaaaa
     9001 acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga gaaaaagaat
     9061 ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt aaacgaagat
     9121 cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg ggttgtgggt
     9181 ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg gtatatccag
     9241 attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac atatgaagcg
     9301 cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca ttatgtacga
     9361 aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg tacatagttg
     9421 ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat ctagatacgc
     9481 atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat tttcatcaat
     9541 tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca cattcaaaaa
     9601 gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac atggtgatgc
     9661 agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc ttgagcctac
     9721 atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag taacgaaaac
     9781 gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag gagcctgttc
     9841 tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa atacactttc
     9901 gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt aagaatcttt
     9961 tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc tccttcaaac
    10021 tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac ttactgacaa
    10081 aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa atcttctatt
    10141 ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca gggtaaaaaa
    10201 aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat aatggcagtt
    10261 aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat cgtcgtagct
    10321 gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta caatcctttg
    10381 aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt atcaaaaggt
    10441 gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat gcaaaaacac
    10501 cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta agcgacttag
    10561 tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta gacgtcgtag
    10621 agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt ggccgtatca
    10681 ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt gttcggatca
    10741 atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa ataaacgtgc
    10801 tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag aaatgattat
    10861 ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca gccaatgaga
    10921 aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc ggttactcaa
    10981 gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag tccagaaaaa
    11041 agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa taatgagaaa
    11101 aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc tctagatgta
    11161 ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg ttattctatt
    11221 ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa tcaagaaacg
    11281 cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac aatccaagtt
    11341 ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc tcgaatcaca
    11401 gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg aaactggcgt
    11461 attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc taaagaaatc
    11521 gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa aattactgtt
    11581 gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc gaaaaatgcc
    11641 tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc tatgaagagg
    11701 ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca ggaagtaatc
    11761 aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag aaaactagaa
    11821 ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat ataagttgac
    11881 tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg aagtccgtgt
    11941 tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc taacactatt
    12001 ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac ataaaaattt
    12061 tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat atcgggatgg
    12121 catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat tctattacca
    12181 tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag taaaagaaat
    12241 cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag ctgatatatt
    12301 gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag tggtccgtgt
    12361 agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta tttccaagaa
    12421 tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa ggattattag
    12481 atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca gtagatgatt
    12541 atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat gataacatcc
    12601 aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt gacccagctg
    12661 gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac ttagtattca
    12721 tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca gatgaagttt
    12781 ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg atcgatgcaa
    12841 cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg gattcttatt
    12901 caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa gggatgaaag
    12961 taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa ttaaaagaat
    13021 cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa tggacacctc
    13081 aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca gcagatgaag
    13141 ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta gtattttatg
    13201 gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct cataagaata
    13261 tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca aaagaacaat
    13321 tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac gcaaaagttg
    13381 ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa cgccgcggtg
    13441 ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc gttgaacgta
    13501 cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac ggtaaagtac
    13561 gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt atcaaagaaa
    13621 tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa gggttctttt
    13681 tttattatct gtttttttat attaacgatt tctatttggt acatttttga ttaataaaaa
    13741 ggggcaaaaa aggggcaaca agttacagtt tttctatatc ttctttcaat ttttctttta
    13801 ctccttttgt cacatgcaaa taaatctttt cagtgatatc actattttcg tgcccaacgc
    13861 gatcctgaat agcatacaga ggagttccta gttccgctaa ttttgaaata tgggtatgtc
    13921 taaaaatatg tgaactaagt tttttatcaa tcttcatgtc agctttatga tttctcaaat
    13981 aggtgttaat tgctgttagt tggaaaggag ttcctttcgt tgtttgaaat agaaattgac
    14041 ccttcggatt taattctaga agctcattgt aaatagctat cgcttttttt ggtaaatcaa
    14101 tttctcgcat tccagcagca gtttttgtag aatcagattt tttcatatca gctattgaac
    14161 gttctctata catcatcgtc ccatttataa ctactgatgc attattattg gtaatgtgta
    14221 catcgtcttt acttaatgcg attgcttctc caggtctcat tccagtcaaa tatagccact
    14281 ggaaaaggag agaatatctt ttattgtgtg aagttgtgaa atctactagt cttttatatt
    14341 catcatcttc taaaaactta tctttaattt ttatcgtttt tgactctcgt ttataatcaa
    14401 taactacttc gttgatagga tttttttcta catagccttt tttcatagcg tatgaaaaaa
    14461 gaagattcaa tttggattta attacactga cgtacttatt tgacaagtca tctttatata
    14521 tcatatcttc aaaaatatta tttaaatcta ctgtattaat accagaaacg atgtaagtct
    14581 caggcatctt cttctttata gtgtttaaga tattattcgt aggataatat gtagactcct
    14641 taacttgcct tttgtaaata actaaccatt cttcgacaag ctcatgaaat gttagattag
    14701 gcttctggag tgttttttca tttagtttta tatcaatttt tttatttaac tccagtaatg
    14761 ccactttctg agtttctcga gacttatttt tataagtaat gctcactttt tttctttttc
    14821 tagtttttgg atcaatatat cgttcattat atttatatac tttttttccg tttttatcag
    14881 ttttggtttc aatccacatt gttttcatct cctatttgtt gctataatag gaatggataa
    14941 gtaagccgat tatagcaggt ttatttttca tcacgtccac aaactttggc gagggagggg
    15001 gcgtgttttt gtattttaac gatttatatt gaatgttgat tcagcacttt cagcaactgt
    15061 actataatca gacggattat ataacactcc ggtttttatc gttacttttg taatatcgtt
    15121 aactttagat ggatctaagt aagctaaact ataaaattct ttactttcag tttttttgaa
    15181 aaacgagttt gttgtcattg tatgcataag atcgtctgaa ctgaaatcaa tttgttggcc
    15241 gttatcaagt atggcgtgtg caagcccatt ataaccataa tctacttcag aattgttttt
    15301 aactttgaat gcaatttgta aaccataaaa atttccttca ctatctttgt gattatttgc
    15361 atcgtagtaa ccagcagcgc tagggtcagc ataattggaa tacttgagta gtttgatatt
    15421 agatatataa atgccgatat caccaagagg aatatctgat tgtgggcttg ccgttccaat
    15481 taattcaatt ttgccacttg tatctctttt ttctttggtc cattgaccaa ctttgaggag
    15541 ggggccatca acctcctgtg aatttttaga agactgtgtt gtactttctg ataacgtaac
    15601 tgaagagtct ttttcgtttg ttttgccagt attatctaca acattagatt ggctacatcc
    15661 ggtaagaaaa aaagcaccaa atactaaccc taaaatcact tttttcattc tttattctcc
    15721 gtttctatga tattattttt atgtaggatc ttagaaacga gatcttagtc cgtgttgcag
    15781 cacgggcttt tttctttata acttttttag agattatagg caaaatagta ggacacaaaa
    15841 atatattatt gtattccgta tttagaaaat cctaattgaa cttcaccaga agttttttgc
    15901 tgtgttgtac gcaatgcttc ttcttcagac attccattct gtactttcca tgcaacaggc
    15961 gacatcccgt atttgttaac aaaatcagta agtgataaag tgtcagcgtc ttgctgaccg
    16021 cttgtttgtt ggtcttctgg attttgttga gatgctgctt gttgttcttt ctgatcttga
    16081 ctgataatat tgccagcatc atctgtagtc aatccatttt cataaagggc cacgccgaaa
    16141 gcttcccact ctttgttgga ccaatttgca cgatcagctg gagttgactg taaagtgcgt
    16201 tgtttcatct gttcatatgt ttcttcttga ggtgcggttt ggattgtatc ctgactggag
    16261 cttataactg ttgggctagg ttccgccgta gcttggttag agcttgtaac tgttgaacta
    16321 gaatctgtct tagatgtaga tttgctagta gaggaactgg tttcagttgt ttcttttgtt
    16381 ttacttactt ttgtttcttg gttagaagtg gcatctgttg attcagcttt tttattattt
    16441 gaacaagctg aaagtagcag agcagtactt aacaacaaca taacgctaac ttttttcatt
    16501 ttataattcc tctttctcgt tgtaatatgt gtgctaacac gggctttttt atataagaaa
    16561 acgataagcg ctttctggaa gtccgtaaag attctttaat tcatcgattt ttttgggata
    16621 ttgatcatta tcttctttat aaagagaaac aatgagatta gcagcaaagc aattagcttc
    16681 gctttcagat ttgcttctag atgttcttgt tgatacatag taactggata agccgcgatg
    16741 aaaaatagcg tgacctaatt cgtgagcgca aatgtagaat ctttcctcag agtctcgcag
    16801 ttcatcattt aagaagatta ttgcacgacc tctaatttct tgaaactgtc ctttgggatt
    16861 ttcgataaaa ggaacgtatt gaattttaat gcccatcttt tcacaaatat aaaaaggatt
    16921 agcagaccgg tatttccgct tcaactcctc gactaaatta atcgtatcca tctccataag
    16981 ctcacatctt tttgcctttt tctttgtctt ctttcacaat atcccagaag gttccaataa
    17041 ggatatcttt tacgcgttgg acctgttcag gcgtcagtgt ttctccgcca taagacatat
    17101 tgacatttga atctagtaat ttatcaagtt caactacttc atcttttgtt gcccagtcag
    17161 gaacttggtt tctaccgagt aaataatcag tagttacatt aaaataatct gctacaagtt
    17221 gtagtctttt agtactagga gttctatttt tccattgata aatcgtgttt ttaggtatat
    17281 ttaattcttc ttccaattga gttatactta tgcctctttt atgagctaat tcctttattc
    17341 tatctagtaa attcattttc gcacctcaca agctacgaaa acactaataa aaaaattagt
    17401 taaaggtgtt gacaactaat aaaattgtta gtatactgtt ttcgtaagct aaaatattag
    17461 ctaaaaagac ttgataacta ataaacactt cacggtcggc aaactctgaa atgtaaatta
    17521 ctaggcattt ctgtgtctta tttagctata tctatatact aataaaaata ttagttattg
    17581 tcaacgaata ttagctaatt ttttagctta cagactattt tttagaaagg agctattttt
    17641 atgtctgaga atttagactt aaaaattcga gcggagatga gaaaaagaag aatgactttc
    17701 aaagaactag ctgcgcttgt tggtatttca ggagcttatt tatcagatat tctaaacggc
    17761 aatcgtgatg gaaagaaagc acaacagcat atcgaaacag tgaaaaaaat attggacatc
    17821 cgataggggg ggtaggcgat gacaaaacta aaaaaacaag attttgtaaa aaaatacaat
    17881 tattctccat ctacttatca acgtcgaatg tcggaactaa aaaatacagc aattttctca
    17941 gcggcgtatg aacgggtcac aggacaagaa gtttggatca atacagaatt atacgataaa
    18001 tttttgtctt tcaaatccta taacaggtta cgcacaagaa agataacacc taaagaattt
    18061 atcgagaagc atttagttga tttataaaaa acagaacatt ttgagaggtg aaggttaatg
    18121 ggcaaattca acagagcgct agtgttcagc gcaccgctaa tcatctacgc tttaggcctc
    18181 tggggaagca ggcaagcgtt gataggaacg attgtttaca tggtttggat ttttatgggg
    18241 cttgatgaag ctgaagctga gtacagagcg aaaaagccaa ccgagggggc tgactaaaaa
    18301 tgaatagaaa agagaaacta gaatgtatat tactattact cagtttaatt ctttcactaa
    18361 tttctctatt gggaagtttg tatttttgat atcaacaatt ttgtggattt gggttctatt
    18421 tagagtaaat atcatttttg tttggtgatt aaggagttta ttaaaattaa ttttccctac
    18481 ttcaaatgca aggtaacaag atatagcact tttaggagga atatttagcg gtacagcttc
    18541 agagtatatt ctattatcat cgactgatcc tcctttagca attaatttct taaatggagt
    18601 agctgaccat ctgcggttta agttagcgga tgaaagttct aaattaacta acatagctgg
    18661 ttctgttgaa tagttagaaa tgattacttt tgtataaatc atatctgcag cgaagtaaga
    18721 agcattaagt tcaacttcta gttgagggcg cattcctttt atttttatcc ctgttaaaaa
    18781 cgtactcaat ataaaactta ttattgacat ccattgaaaa attgttaagt gaaaaaaatt
    18841 caaaataaac accaccagtt tttaactaaa ttataccaaa aaggagagaa gaaataatgc
    18901 aagaattagt aattttgaaa aataaagaag ctgtgactac gagcttacaa gtggcagaaa
    18961 gcttcgagaa aaaacatcaa catgttttaa gagatattga tgcactaaaa aaagatgtgt
    19021 ccaattttgg acagatgttt gtagaaggta atgaaccaga ttcatatggc agaaatcgac
    19081 gagttttctt cattagtaga gatggatttt tcttgctggc tatggggttt acaggaaaga
    19141 aagctatcta cttcaaacaa aaatacattg aagcattcaa cgaaatggaa gatgttattc
    19201 gcaagaatac tgttcctcaa acaattgaag atatgatgat ctatcaatta gaagaaatga
    19261 aagatgttaa aaaagatgtt tccatgctta aagatactat gcgaattagc ggacaacaag
    19321 agtttgaaat taagcaaaaa ggaaatatga aagttatggg agttctaggg ggaaaagaaa
    19381 gccgagctta tgaagaaatc agcaaaaaag tattctcaaa attttggtct gaatttaaac
    19441 gtaccttttc aatcccaaga tatggcgagt tacctcgtaa gagattcgat gatgctgttt
    19501 catttattga aatgtggttg ccagaaactg cgatccgtat ggaaattgat caactgaaca
    19561 gacaacagag actttttggt gatgacaatg aatagagctg aagcgctaag aatagggacg
    19621 gcaattgcta attgctggtg gaaatactat aaaccaatca tcctaagcca acaacatatt
    19681 gacaagcaaa aagcatggca acaaataaaa aagtgactcc gccggcaagc aaagagtcac
    19741 aaagaaaaca catcataagg agattttagc atatggaaaa agaactttcc actctagatc
    19801 aatatttgat tgatcctgat tggggcaagc cgaaaattga ggaaacaagt ggtcgaaaaa
    19861 tcagacgaaa tcttttgacg aatgaagaac tagcttggga tcaagatgat ttaggcaacc
    19921 atgtaactat ttgggatcat gtttatctta tccatctatc gaagcattcg aataaacctg
    19981 aatatattta cgtcatcgaa gatggcttga ttgatgcgct agaagagtac gacagagata
    20041 acttgattga tatctcttat tacggaccag gtaagaaata cattgctgaa atggaggcag
    20101 aatttgatga gtgaaatcaa agggacaacg aactttgaaa aactttttag tcgtaagtta
    20161 aataaaattc tcaagaaaaa aggaaatttt gattatttat cttgggctca cgcgtgggag
    20221 attatgaaaa agaatgatcc acaggcaacg gtaactatta atgagtacaa acactacagg
    20281 gttgtttctg gaactcatca agactttctt gttgaggaat ataaaccttt tcttatggat
    20341 gaaactggga cttatgtatc tgtctcagta acggttaaag gacacacgga aaccgaatta
    20401 tttcctgttt tagattatcg aaaccaacca gttgttaaac caaatgcaat gcaaatcaat
    20461 aactcattga agcgatgctt tgtgaaagca ttggctctac acggactggg attatatgta
    20521 tttcaagggg aagatattcc aacaccacct agaatcgata caaagaaatt aaacatgcta
    20581 gagacgattc tagagctttc aatgagcaga tgggtaaaga tatgaccaaa accttaatcg
    20641 aatatgttaa tgagcagaca gataagttag ggctcttagc tgataacgtt gaaactattg
    20701 aacagttaag ctatgagcaa tgtgccttga tggagcgagc aatagcagct aagagaaaag
    20761 aattagataa gaagtgatat gagtgtttaa accattaatc gattcatatt cagcggttct
    20821 gaaaaagttc aaaggaaaag acataagcgc aaccatcaat gaggaagtga acattgatcg
    20881 actaaagacg atgtatgacg gctacgatgg tgatcgagtt attgaaattc gttttattga
    20941 tcctagacgt ttcacagtac agcaacgaaa cttcatctat gcactcatag gcgatatttt
    21001 catcgataca ggcatgccaa cggacttctg gaaggaattc ttttacttcc gtttcgaagg
    21061 tgtcacaggg cgcgaaataa gcctcaaaga tgaatcgaat acgactgtga gtgatgccaa
    21121 tatcttagca aatatcatct tagattttat ctttgaacat catattcctt tcaaagaagg
    21181 ctatgagatt ttaccagcga atcaagaata ttacttctac aaatgcatca caaaaagagt
    21241 ctgctgtatc tgtggcaaaa caggagctga tatcgatcac tttgacaaag cgctaggaag
    21301 acgaaagcgc aaagaagttg atcattcaga gtacacattt gcagcactct gtagaattca
    21361 tcacacggag aaacacaaaa taggtgtgac caatttcaaa aataagtatc aaatcaaagg
    21421 gattaagtta aaccaggaga caatcaagaa attaagaatc gggggctaat gatgattaat
    21481 ttaaacgcag tagcgtttga acaaacatgg cgcactaagt ataaaaaaat gagtccaaga
    21541 gacaaattgt tcttagaaat catgacattt gctttcattg gtacacaagc tgaacaaagc
    21601 gatattagtg ttgaaaaaat taagacgaat agattagtta atggaattac agagacttgt
    21661 taccagtaca cgattatcgt cgtggatgag gaggaataat tttggcagaa agaagaatgt
    21721 tcgcaaagac aattattgat tctgatgcat tcctagatat gcctttatcg acacaggcat
    21781 tatatttcca tctatcaatg cgcgcagatg atgatggatt tattaataat cccaaaaaaa
    21841 tacaacgtat ggttggttgt ggtgatgatg atttaaaact gcttatggca aaaagattca
    21901 tcttagtttt cgagagcggt gtgatcgtca ttaagcattg gaaaatacac aactatattc
    21961 gtaatgatcg ttacaaaccc acgttatatc aggatgaaaa agctttacta gcagacaaag
    22021 ataacaaagc ttatacattt gcagaagagc tttctaaaca tgatgaaaaa cttggtatac
    22081 cagatgacaa ccaagcggta taccaaatgg atacacaggt taggttaggt aaggataggt
    22141 taggtaagga tagtaaagag ataaaagatt taacgccttc gaaaaaatcg aaggctaagc
    22201 ccatccgtca taaatacgga gagtat
//
LOCUS       DASHXG010000040        22055 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.040, whole genome shotgun sequence.
ACCESSION   DASHXG010000040 DASHXG010000000
VERSION     DASHXG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.040"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            278..787
                     /locus_tag="U2R59_001856"
     CDS             278..787
                     /locus_tag="U2R59_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8966242.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="U2R59_001857"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="U2R59_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8966243.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="U2R59_001858"
     CDS             2322..3302
                     /locus_tag="U2R59_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8966244.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="U2R59_001859"
     CDS             3424..4842
                     /locus_tag="U2R59_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HEM8966245.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="U2R59_001860"
     CDS             4913..6382
                     /locus_tag="U2R59_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8966246.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="U2R59_001861"
     CDS             6392..6859
                     /locus_tag="U2R59_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8966247.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="U2R59_001862"
     CDS             6895..7767
                     /locus_tag="U2R59_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8966248.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="U2R59_001863"
     CDS             7848..10382
                     /locus_tag="U2R59_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8966249.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="U2R59_001864"
     CDS             10538..11311
                     /locus_tag="U2R59_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8966250.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="U2R59_001865"
     CDS             11304..12095
                     /locus_tag="U2R59_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8966251.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="U2R59_001866"
     CDS             12105..12596
                     /locus_tag="U2R59_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8966252.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="U2R59_001867"
     CDS             12614..13024
                     /locus_tag="U2R59_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8966253.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="U2R59_001868"
     CDS             13028..14428
                     /locus_tag="U2R59_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HEM8966254.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="U2R59_001869"
     CDS             14451..14825
                     /locus_tag="U2R59_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEM8966255.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            15314..15508
                     /locus_tag="U2R59_001870"
     CDS             15314..15508
                     /locus_tag="U2R59_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966256.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            15498..15851
                     /gene="tnpB"
                     /locus_tag="U2R59_001871"
     CDS             15498..15851
                     /gene="tnpB"
                     /locus_tag="U2R59_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEM8966257.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            15953..17500
                     /locus_tag="U2R59_001872"
     CDS             15953..17500
                     /locus_tag="U2R59_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HEM8966258.1"
                     /translation="METTDTLLQLLQEAHKTNQTQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKTDKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            17652..18080
                     /locus_tag="U2R59_001873"
     CDS             17652..18080
                     /locus_tag="U2R59_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8966259.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            18067..18309
                     /locus_tag="U2R59_001874"
     CDS             18067..18309
                     /locus_tag="U2R59_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966260.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(18609..18824)
                     /locus_tag="U2R59_001875"
     CDS             complement(18609..18824)
                     /locus_tag="U2R59_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966261.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            18931..19245
                     /locus_tag="U2R59_001876"
     CDS             18931..19245
                     /locus_tag="U2R59_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966262.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            19349..20527
                     /locus_tag="U2R59_001877"
     CDS             19349..20527
                     /locus_tag="U2R59_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8966263.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            20930..21223
                     /locus_tag="U2R59_001878"
     CDS             20930..21223
                     /locus_tag="U2R59_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HEM8966264.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         7622 a         3221 c         4374 g         6838 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attacccgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag agtaagcgcc
    15241 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
    15301 ctggaggttt tctatgtata aattaaatga gattgttcct gtccaattag gaaacgaaaa
    15361 gagtgcacca gaaaaaggta aacccgcggc tgccaagtta gcgatgcgca tcaaaagaga
    15421 gaatggttct gaagttttga tctataacgg tattaacaat tatattcttc aagctatttt
    15481 gaaagaactg ttgtccaatg ctttatgatt tacttcaaac caaacatatt tatattgtgt
    15541 gcggaaaaac agatttgcga aaaggaattg atggtcttgc cagtcttatt caacaagagt
    15601 atcaactcga gctttacgaa gatgccgttt ttttattttg cgggaaccgt caagaccgtt
    15661 tcaaacttct ctattgggac ggtgatggtt ttcttctctg ttataagcgg atagaaaacg
    15721 gcaagttaaa atggcctcgg acgaaagacg aagttcgaac cttaacgaac caacaggttc
    15781 gatggttgtt agaaggatta agtatcgatc aacctcgagc tattttgcca ggaaaaaaag
    15841 gagtttttta agctgggggg ttaacacaaa aaatgtgttg aacccctatt tcttgtgcgt
    15901 ttcttgtggt attctgtaac aaaatcagtt cgattcaagg tggtgaaaaa ttttggaaac
    15961 tacagatacg ttgcttcagt tgcttcaaga agcccataaa accaatcaaa cacaacaaca
    16021 aaccattcag aatcttacaa ctgaaatcca actattgaat gaaaaggtca attatttaac
    16081 caacaaatta tttggacgct ctaaagagac tctctttgaa gaaacgaatg ggcaattgaa
    16141 tctttttagt gatgaagaaa tttctgtaag tgttccagaa gcagctgcca ccattattcc
    16201 agtaaaagga catcaacgag ttgtaggaac gaaaacagac aaaatcaaac acttacctat
    16261 aacagagaaa gaacatctcc ttcctttgga agaacaattt tgtgaacatt gcggttcaca
    16321 gatgaaagat atcggacgga caaaagtacg agaagaaatt cgtttccatc aggctatgtt
    16381 ggattgtctc acccattatc aacataccta ttgttgtaaa agctgcgaaa aagaaggact
    16441 ttcttctttt aaaaaagcga tcgttcctaa acctttgatt tctaatagct taggttccaa
    16501 tagtttagtg gcggaaacga tccggatgaa atttggtcag aaagttcctg cctatcggca
    16561 agagaactat tggaaacaaa cacatgggtt ggatatttcg agagataata tcaccaattg
    16621 gcatattaaa gcagtgcaaa acgcgttaga ccctttagga gaacgattaa gagtctatct
    16681 taatcaagaa gagattctac acggggatga aacaagttat cgtgtgattg aaagtgccaa
    16741 aacagatacc tattactggc agttttgtac aggaaaagac agtcagcatc ccatcgttta
    16801 ttatcaccac gacgaaagtc gtgctggaga tgttccgaaa acttttctca aggagtttac
    16861 agggtattta cactgtgacg gctatagcgg gtataatgcc gtggaaagtg tacgacttgt
    16921 ctattgtttc gcgcatgttc ggcggaaatt tttcgaagca attccaaaag gaaagaaaaa
    16981 cacggatatt cccgcagctc aagcagtcaa acaattggat aaatggtttg tcctagaaaa
    17041 gaaatggaaa gacttttctc ctgagaagcg attaagctgt cggcaacaag aactgcgtcc
    17101 attatttatt gctttttatg agtggatggc aacgatagat cctgttgcaa aatccaagtt
    17161 ggatgcagcc gttcaatatg cgtgtaaact acgaagtggt tttgaaccta tttttgaaga
    17221 tggtcgttta gaactcacaa ataatcgtgc ggagcgaaat atcaaagagc tggtgatagg
    17281 acggaaaaat tggttgcatt ccacaagtct tgaaggagca cgaacttcag gaatcattct
    17341 gagtgtatat aaaacagcag aacttaacgg attgaatcct gtaaagtatc tagagtttct
    17401 atttgataag ataccaaatc ttcccgtact ttcagcagaa actttagatc aactgttgcc
    17461 ttggaacaag gatgtacaac aacatttttc tcgtaactaa aaacgccaaa cattcccgat
    17521 tctattctat aggtcgggtt atttgacgta caggtactgt tctatggggc gcttacctcc
    17581 tagattgtag taataatgga aagggataga agtaaaacga gttgaatgaa ttttttgagg
    17641 gggagaatat tatgggcgac tcagaggaaa cccacattca acatacgttt gacagttttt
    17701 gtaagaaagt agtctgcaat gaggcgttaa atattcaaaa gaagtacgct agatttcgcc
    17761 aacggcaaat atcaatggaa atattggaac aaaaagggtt aggtacagag ttctattatt
    17821 tggaaccaaa tttgaatagt agtggtactt ttattgtcct tggtatgaaa atctttattt
    17881 ccaatgagga gttggcaaat gcgattgcag cattacctag tcaaagacaa gaaatcattt
    17941 ttatgtcctt cttcatcggt cttaatgatc gtgaaattgg cgatattatt gggaaaagtc
    18001 tcggcagtgt ttggtaccaa cgacaaatgg ctttggaaga gctaggaaag tatttgggtg
    18061 tcaaatatga agcaaaataa acgatatata ccattcatac cactaacgac aatcaaagcc
    18121 gcagcttctg gtgattcaat tgccatgtcc atcgttctgt caaaatatca aaattatatt
    18181 tcacggttag ccatgaaacc agtttatgaa gaagaaaaag gaatggttat gtatgtagat
    18241 gaatatatgc gtagacaact ggaaacaaaa ttgattgaga agatacttga atttgataca
    18301 actcgttaaa gtattttttc cctttccttt tcattctatg gaagtttttt atcgggtcaa
    18361 aataaaggat ttccataggc tgaaaatagc ctagcgctct ttgacaaatg aatagcaaat
    18421 ctatcagtac atgtagattt tgattctcta gttacgccat gacaaggtta gcttttaagc
    18481 gacaaatttt aatatgagaa tcgcgactac gataatgata cttccgtaac caaatcggcc
    18541 cgccattact ggggggaggt gagattccta tgtgctttgg caaaacagct gatagatcag
    18601 aaaaactact atttccatat ttcgattttg gttggcatat ttttcatgcc aaattctgtg
    18661 attttaatag catcggcaag atttaatttt tcttcagctc tctctccact tttaagtttt
    18721 tttactgtac tcaagttgat tcctgttccg aatgctattg cattagccgt agatttttca
    18781 agaatttctt taattatttt tatgtctgca attccttgtt tcatattaaa aattcctctt
    18841 ttctagtccg ttttgatgga gtactggagt gtttttttac aattttaagg ggtaccgtgg
    18901 tggtcgtttt gattttgaga gagaagggtg atggagttgg aagttaaaac aaatgttaat
    18961 tctctggaaa tagagttcta ttcaatttta caaaaaaaac tggaagatta cacggaaaaa
    19021 ttgcttgcag tcagtcattt acctctggta ttaacaaata ctgatttaaa gcgactattt
    19081 cagataagtg atagtacact gaaccgttta gtaaaacttg gtgagtttcc tccctgttgg
    19141 tacgggattc gaggacacta ttttcgtgat gatgttttag aatggatgag aaagagtgat
    19201 tcgaatgact atcgagaaaa attgcgacta cttcgatctt tataagttac attttctttc
    19261 taagatgcgg tacaatgatg acatagatag aaagatttcc aaagggtttc tgcttgttgg
    19321 gttccttcaa aataggagga atcaataaat ggaaaaaaca gatcgattca agaagcaaat
    19381 cagttctact ggtaggatca catggtactt tcaagcatat cgaacaacaa gacgtggctt
    19441 taattcaaaa cgtgaggcgc aactcgctta tctggaaatg gagaaacaac aaaggcttaa
    19501 gaaaaaaatt gttgcaagca atgacaagtt tagtgttgta ggtgagcaat ggttccaata
    19561 ttaccgttcg ttaaatgaac aaaaggaaat aacctatgat aagcgagagg aacaattaaa
    19621 aattattgtt cgatggattg gtgataaaaa gttgtctgat ttgacaccag agtgccttca
    19681 agaattgctt tttaccttaa aggaatgtgg cgttaatgga acaaatgttg gctatgccaa
    19741 aaatagttta caatcactta ttcaagttct aaatatgatt tttaaatatt gtcaaagaaa
    19801 gaatttgata agtgaaaatc caatgaagtc tgtgagaatg ccaaaatatc agttaacggt
    19861 aactgattta aaagaagcca taaataatat tgaggacaag tttcttactg tcgatgaatt
    19921 gagaactttt ttgaattatg gcattgttca tgaggaatta ccgatgtctg tacttttcca
    19981 tgttctattt tacactggct gccgagtcag cgaggcgctt gctctacagc ctggagatat
    20041 agatttcaaa agaaatgaaa ttctgttcta taagcaaacg gcagttaaag gtaagagtaa
    20101 ggattttcga attgaaacta ctaagacagt tagttctgct agacgagttc tagtaactcc
    20161 tctagttatg gaaaagctac aacagttgat taaggctttg ggtgagatga ggcaacatta
    20221 caggtttatt atagaagaaa catatttgtt tgtgtatctt gattctagta aacgtggtgt
    20281 tccttatcgt cgagagtatg taaatgatca cgtcaaacgg tgcgtgaatc gctcaggaat
    20341 taataagcca tttcatactc atttagctcg tcatacaatg gcaagcttag tagcggaaca
    20401 ctgtagctgg gaagtcttga aagatcgctt aggccatact gaccaaacaa cttcgaaaat
    20461 ttatcgccac ttaacgtcaa atgaaaaggt aaaacctctg attgctttta gttctttaga
    20521 gagttaaaaa aacggtgaaa gcactggtat tacaggattc ttgaaaaacg attttttaac
    20581 aaattagtca atatgtagtc agaggtaata aaaatccttt tatatcaata ctttaacgac
    20641 ttttcacaag tatcaaagaa atccgtcgtt aatcattgtt atcagactga gaaagaaccc
    20701 ttggtattca agggttcttt tttcttagca tgtaatttga acaccctgat ccagtttttt
    20761 ctttaattat tggtagggga gaataatgga ttagaataaa tctacctata agtagtagta
    20821 aaaaaaagag cactatgata atatctttct taagagtaac cgctttaata aaaaatccag
    20881 aatattctaa cataaatgga gtattcttag aatcaaaagg agaaagaaga tggtttatac
    20941 ttatacggag caagaaaaga tgaaagtttt agacacattc atgaatgatg gaaaagtaaa
    21001 acaagtacca agttcaacaa aaaagaaata catcctattg aaagaagtct tgaaacgctt
    21061 tgaccatgga gtgacttata cagaaacaga ggttaattcg atactgctga acgtattttc
    21121 tagtggcgat tatgtcgaac aaagacgtta tctaatcaca tttggctttt tcaaaagaag
    21181 ttcagacggt cgggcatatc agatgatggg aattgaaaat tagaagtttt aatttatact
    21241 cattgaaaaa agttcaagta tgcgatattg gttctacacc gcatacttga actttttttg
    21301 tcatctgtat ctataataca aagccaagaa cgttattcaa aatatggata gctatgataa
    21361 aagctaatga gcgattcgca gttaaataag caatcgtcag taaaatcgtt ccaggagcgt
    21421 acatgaaaaa atcaattgga tgcgttacat gaataaagat aattctcttt tatttgtacg
    21481 aataaatacc aaaacgtacc tcctaaaatt agattttgga cagatgccct ttaaaaagat
    21541 aacaagattt cgttcttgaa acaatatata tgcttttatt ccaatgaggt tgtgaaaaca
    21601 gtattttgtc ctgagcgtta gaaaattgaa aatggggaat agcaactcgt actttaccat
    21661 tttttaagtg aatacaagat cagctaattg aacaccgttt attcgtgatg agggacacaa
    21721 cactgcagtc gacacatttc tcttttatgt tcaaagataa caaatattta aaacaaagaa
    21781 aaatagtaga taatcccgtc ctaactcttt tattcttccc tcatagcttc caaatttaag
    21841 caatacttca attaatcaag ttttatcttt ttttttcaat aatcgtaaaa aaagagtatt
    21901 ttttatttaa aaataaaatc tttgtattaa aggacaagac taaaataacc ttagaataaa
    21961 aagagaaaaa aagccccaaa ctttctatac atcaataaaa taataaaaat taaatttaga
    22021 ataacgtgta aaggattatt tgatgatttt ttatt
//
LOCUS       DASHXG010000041        21972 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.041, whole genome shotgun sequence.
ACCESSION   DASHXG010000041 DASHXG010000000
VERSION     DASHXG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.041"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="U2R59_001879"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="U2R59_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HEM8966265.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="U2R59_001880"
     CDS             complement(2017..2919)
                     /locus_tag="U2R59_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8966266.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="U2R59_001881"
     CDS             complement(2916..3608)
                     /locus_tag="U2R59_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HEM8966267.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="U2R59_001882"
     CDS             complement(3651..4292)
                     /locus_tag="U2R59_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8966268.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="U2R59_001883"
     CDS             complement(4330..4644)
                     /locus_tag="U2R59_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966269.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5984)
                     /locus_tag="U2R59_001884"
                     /pseudo
     CDS             complement(4632..5984)
                     /locus_tag="U2R59_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5981..6913)
                     /locus_tag="U2R59_001885"
     CDS             complement(5981..6913)
                     /locus_tag="U2R59_001885"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEM8966270.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="U2R59_001886"
     CDS             complement(6910..7686)
                     /locus_tag="U2R59_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEM8966271.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="U2R59_001887"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="U2R59_001887"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEM8966272.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="U2R59_001888"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="U2R59_001888"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEM8966273.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="U2R59_001889"
     CDS             complement(12011..13291)
                     /locus_tag="U2R59_001889"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEM8966274.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="U2R59_001890"
     CDS             complement(13310..14236)
                     /locus_tag="U2R59_001890"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEM8966275.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="U2R59_001891"
     CDS             complement(14249..15532)
                     /locus_tag="U2R59_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEM8966276.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="U2R59_001892"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="U2R59_001892"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEM8966277.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="U2R59_001893"
     CDS             complement(16320..17231)
                     /locus_tag="U2R59_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEM8966278.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="U2R59_001894"
     CDS             complement(17228..17692)
                     /locus_tag="U2R59_001894"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEM8966279.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="U2R59_001895"
     CDS             complement(17697..18395)
                     /locus_tag="U2R59_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEM8966280.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="U2R59_001896"
     CDS             complement(18382..18768)
                     /locus_tag="U2R59_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966281.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="U2R59_001897"
     CDS             complement(18915..20585)
                     /locus_tag="U2R59_001897"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEM8966282.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="U2R59_001898"
     CDS             20768..21001
                     /locus_tag="U2R59_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HEM8966283.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="U2R59_001899"
     CDS             complement(21100..21531)
                     /locus_tag="U2R59_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEM8966284.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..>21972
                     /locus_tag="U2R59_001900"
     CDS             21610..>21972
                     /locus_tag="U2R59_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HEM8966285.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADN"
BASE COUNT         6207 a         4911 c         3883 g         6971 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata at
//
LOCUS       DASHXG010000042        21837 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.042, whole genome shotgun sequence.
ACCESSION   DASHXG010000042 DASHXG010000000
VERSION     DASHXG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.042"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            32..160
                     /locus_tag="U2R59_001901"
                     /pseudo
     CDS             32..160
                     /locus_tag="U2R59_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
     gene            274..513
                     /locus_tag="U2R59_001902"
     CDS             274..513
                     /locus_tag="U2R59_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966286.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            625..819
                     /locus_tag="U2R59_001903"
     CDS             625..819
                     /locus_tag="U2R59_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966287.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            905..1576
                     /locus_tag="U2R59_001904"
     CDS             905..1576
                     /locus_tag="U2R59_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HEM8966288.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1629..3605
                     /locus_tag="U2R59_001905"
     CDS             1629..3605
                     /locus_tag="U2R59_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8966289.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3620..4372
                     /locus_tag="U2R59_001906"
     CDS             3620..4372
                     /locus_tag="U2R59_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8966290.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4388..5143
                     /locus_tag="U2R59_001907"
     CDS             4388..5143
                     /locus_tag="U2R59_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966291.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            5156..5416
                     /locus_tag="U2R59_001908"
     CDS             5156..5416
                     /locus_tag="U2R59_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966292.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5413..7503
                     /locus_tag="U2R59_001909"
     CDS             5413..7503
                     /locus_tag="U2R59_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8966293.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7530..7994
                     /locus_tag="U2R59_001910"
     CDS             7530..7994
                     /locus_tag="U2R59_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966294.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            7991..8233
                     /locus_tag="U2R59_001911"
     CDS             7991..8233
                     /locus_tag="U2R59_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HEM8966295.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            8251..8553
                     /locus_tag="U2R59_001912"
     CDS             8251..8553
                     /locus_tag="U2R59_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966296.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8623..10686
                     /locus_tag="U2R59_001913"
     CDS             8623..10686
                     /locus_tag="U2R59_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966297.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10686..13298
                     /locus_tag="U2R59_001914"
     CDS             10686..13298
                     /locus_tag="U2R59_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEM8966298.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            13295..15826
                     /locus_tag="U2R59_001915"
     CDS             13295..15826
                     /locus_tag="U2R59_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966299.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15876..16208
                     /locus_tag="U2R59_001916"
     CDS             15876..16208
                     /locus_tag="U2R59_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966300.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            16209..16802
                     /locus_tag="U2R59_001917"
     CDS             16209..16802
                     /locus_tag="U2R59_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966301.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            16965..18989
                     /locus_tag="U2R59_001918"
     CDS             16965..18989
                     /locus_tag="U2R59_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEM8966302.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            18989..20194
                     /locus_tag="U2R59_001919"
     CDS             18989..20194
                     /locus_tag="U2R59_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEM8966303.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            20210..20854
                     /locus_tag="U2R59_001920"
     CDS             20210..20854
                     /locus_tag="U2R59_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966304.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIEQLKQQDGTKAKEEVTEAQSKTAEEFG
                     KLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20865..21671
                     /locus_tag="U2R59_001921"
     CDS             20865..21671
                     /locus_tag="U2R59_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966305.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFAVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21693..>21837
                     /locus_tag="U2R59_001922"
     CDS             21693..>21837
                     /locus_tag="U2R59_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966306.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNG"
BASE COUNT         8054 a         3417 c         4524 g         5842 t
ORIGIN      
        1 cgtaagaaac cgttaggttt agctaagtgg tgagtagttc acaatgacgc ttacgaatga
       61 taatggagac gaattatctg ttgaagatac ttggtcatat ttgagtgatt atattgtcag
      121 cgttgaaatc attgaatttg tagcggataa agaagaataa aaactggagg aataaatttt
      181 acagataaag gcttagaaga agtcacgacg aataataaaa aggtagtatt accttaggca
      241 ttgagtaagg aattcattta ggaggaaaat tagatggcgc gaccagtttt agaggcgatg
      301 gatatggata ctttgacaaa aggaaggtat gtacagctgt tagctcgtgg ttattcacct
      361 aaagatgtat tcaaatccct gtctaaagga acagatatgg aaaaagaaag attacgaaaa
      421 gaattcgatt attggagaac ccataatgga atcaaggatt tgaaaccagc acggccagta
      481 attaaacgaa agaaaaagat aacccaagac tgaagtgtag agcgtatgtg atcataggct
      541 tttttatttt tgcaaaaaac aaggaaggta ggaaaactca tgaattatga agaaatcgaa
      601 aacagaaaaa aagtgtcgaa ataaatggaa gaaaagttgc taaaaacgat gaaacaaaaa
      661 caccttaaaa gattatctgt catgcaatat atcaatgata tgcagataac aggaaaagag
      721 aaagcttgtt tgttaggttc aatgaaaaac tttgaacagt tgagacgaac ttatgtgaaa
      781 acaagttcta attgtcaact attgttagaa gtctcatgac attcattaat agaattcatt
      841 tttaaaactt tttctatgga aatgagaaaa agattttttg ttttgtctga aagggggtag
      901 ctggatgaga aaatggttat ttggtttttt aggagtcgct ttaatcgtct tttgcagtgt
      961 gtttggctat gttagctacc aaaaacatga aggagaggtg tttaagcaaa atatagaaaa
     1021 aaagatgccc gtagatcaaa tcaatgcaca tgcaaagagt tataaggagg atgcaacgaa
     1081 cgtcaataat gatatgtctt tggggcaaat gttgtccata caacaagaag caatcgaaat
     1141 gggcgtcaat aaacaagtat ttgcacaaat tcagattcct gcacttggtt tagcattgcc
     1201 aatttttaaa ggggcaaatc aatacacttt gagtcttgga gcggctactt atttttatga
     1261 agatgctgaa atgggcaaag gaaactatgt cctagcaggt cataacatgg aaatgccagg
     1321 tgttttattt tctgatattc aaaagttgtc attaggggag gtgatggact tagttagtaa
     1381 cgatggcgtc tatcgttaca aggtaacgcg taaatttatc gtacctgagt actttaaatt
     1441 aatcgatggc gttcctgaag agaactcttt cttgtctttg ccaaagaaag gagagaaacc
     1501 cttattaacg ttgtttactt gtgtttatac gtcacaagga aaagaaagat acgtggtaca
     1561 gggagaacta caataacaag gttttaatca acgtgagtcg ttgaaatatg aaatgaggag
     1621 agtaaaaaat ggcaataaat cggtatgtaa aaaaagctgg aatgcttatt ggaatgttag
     1681 gaatcattgc aggctgcttt cagggatatc gagcatatgc agaagatgtc acgcaaaaaa
     1741 cgccaccaga gaaggtcaat atcacggttc ataaattaat gtacgatcaa ggaacgcaat
     1801 tgaatgttga tattgacggg atcaaaaacg atggttatac gcacgatcaa tatcctacag
     1861 gtgtaacgaa atacaacaag gcagattatg gtgatgttga gtttacgtta ggaaatatta
     1921 cggatcaagt attaccgaga gaagattctg atctaaccaa cgcgaaagtg gacgagattg
     1981 tacaagatgt agaagacaag ggatctaaca gtgagtacgt caagaatgca accaacaaaa
     2041 ttacttcagc tgtagatgaa aatggtgaga tcacttttac tgatcaacca gcctatgtca
     2101 attccaaagg gaatgtatat gtggtttatg aaagtaaatc cgctgctgga ttagtcacac
     2161 aaaaagcaaa accaatggtt gtgattgcgc caatgacaga taaaacagga tcaggatttt
     2221 taaaaaatat tcatttgtat cctaagaaca ttgtttctaa gttgagtttt gaattaacga
     2281 aatttggtga cgatggcgca gaccaaagca aacaaaccct tttaaaaggg gcaaaatttg
     2341 agttatacaa gggcgaacct ggaaaaggaa caaaattggg tgatcttgta tcggatgatc
     2401 aaggaaagct gactgcgact gatttgacgt taggaaaata ctattttgtg gaagttcctt
     2461 cggaagttgt agtgggatca gatcaagaac caacagcaga tcaatattta ttaggcgcag
     2521 acgctcgcaa cgatgcgcac aataaattaa cctttgaaat tacgaatgat ggcgtgacaa
     2581 gtgacttaaa agcttcatac gtaaactata aagcaccagt gatcgataaa acagtaacaa
     2641 atggaacagg acaagaacat tctttccaaa ttggtgacgc agtaaattat caaggaacga
     2701 ttcatattcc aacagacatt gcaggtggcg cagacggtat cacagtaaac ggtgtgaaaa
     2761 gtgaaacttc tccttacagt gtatttaaat ggggagatac agcaggacag ggactttctt
     2821 atgtcgctgc taaagcaaat atcaaagtaa caaataaaga tggatctgtg gtattaaaag
     2881 aaaatacaga ttataaaatc caaaattcag aaaatggctt tgtgatcgat tttatcgtga
     2941 ataatggcca agtaagtgat actgtagcaa gtttacacgg acaagatctt caaatgactt
     3001 ataacatgta tgtaaatgac agcgcagctg ttgccaatcc attaacaaat agcgtggatt
     3061 tcgtttataa caacaatcca tttaatcagg aagaacacca cgaaaaaacg aaagctgacg
     3121 ttgtgactta tggtgcaaaa ttcttaaaag tcgatagcgg actatttgga acaggaatca
     3181 aagcaacacc gcttgaaggc gcagaatttg ctgctaaaaa cgcagaagga aaatattatg
     3241 gtggattagt tgatacggat aaagacggtg tcaaagaagc agtatgggta gacgatgtag
     3301 caaatgcagc gatcctaaaa tcagataaag aaggtcactt tgaaatcact ggtttaactg
     3361 aaggtgaata ttcactggaa gaaacaaaag cgcctgaaaa ctatcaaaaa ttaacgaaag
     3421 agatctcttt caaagtagac aaagattcat acaaagaaga aaaccgaatc acgatcaaaa
     3481 acaatcaaaa agcttccgta ccaatgaccg gtagcaacgg ttttcaaacg tatgtattaa
     3541 tctcttgctt gttgctagga gcaggggcac tttctgcagt tgtttacttt aagaagaaag
     3601 cctagaagga tcaaaaccaa tgattatcag gaagcctaag aaaaagcgaa tcatgggtaa
     3661 atggatcatt gctttctggt tactttcagc tgtaggtgtc ttacttttga tgcctgctga
     3721 agcgagcgtg gcgaaatacc aacaaaatca gcagattgcc gcaatcgatc gaacaggaac
     3781 ggcagcagaa acggattctt ctttggatgt tgctaagatt gagttaggcg atcctgttgg
     3841 tattcttaca attctaagta tttctttaaa actaccaatt tatgacggaa cgtccgacaa
     3901 aattttagaa aatggtgtag gtattacgga aggaactggt gatattacag gaggaaacgg
     3961 taaaaatcct ttaatcgcag gtcatagtgg actttataaa gataatcttt ttgatgattt
     4021 accttcagta aaaaagggag aaaagtttta tatcaaagtt gatggtgagc agcacgctta
     4081 tcaaatcgat cggattgagg aagtgcaaaa agacgaacta caaagaaact ttgtcactta
     4141 cttagaatca aatcccaatg aagatcgagt aacgctaatg acatgtacgc ctaaggggat
     4201 caacacacac cgttttctag tgtatgggaa gcgagtaacc tttacaaaat cagaattaaa
     4261 agatgaagaa aataagaaac aaaaattatc ttggaaatgg cttttaggaa gtactgtttt
     4321 tctttcagtc atgatcattg gttcgctatt tgtttataaa aagaaaaaat aaaggagggt
     4381 aaccaacatg agaaatagaa aatggctatt tgtttgtgca gccgctcttt tttctttcac
     4441 tgcctacaca cagttgacgt ttgcagacag acaagaaagc acggatagca cagaacaaac
     4501 aatccaaacg tcagatagca gcacgattca aagcagcgat gaaaccgtcg attcgtcaac
     4561 agttgattct tcagaagaac ctaaaattgc tgaagacgat caaatagtca aacagaccat
     4621 tcacgttcaa aagattattt cttcagaaca attagacaac caggggcatg aaaaacaaga
     4681 aggagtaaat ggcgcgaagt tttctgttta tgatgtatcg gacattttac aaaagatgga
     4741 tgttaaggat ctcactactg accaaattga atcccaatta aaaaatcgag tgaaaaaact
     4801 atccagtgat caattgaagc tagtttctaa tgaagaaaca aagacaattg atcaacaaac
     4861 aggtgtcttt gaattctcgg tagaagtaca ggcaaatcag aaacaagctt attatattgt
     4921 caatgaatca agtcctgaaa acatttctaa tagcgaggat attttgctat taacacctgt
     4981 ttctgataaa aacggtgaat tcttaaagga tgtgtggatc tatcctaaat cagaagcttc
     5041 gcaacctaaa gaagaagtaa aaaaaatcgt ttctactggc gtaaagaaaa acttctttga
     5101 gaattgttgg gattttgtta ctcacttgtt ttctagagat taaggaagaa ataaaatgaa
     5161 actgatcaaa ttattattat tcaatttttc ttgtttaacc gcagtctttt tgtactgcgg
     5221 tttattattt tctaaactat ctattttgcc aagctaccaa ctatacctaa tgaggatttt
     5281 aaacatacca gctgcttcca tgccgctaga tattatggaa aagctcatta ggaatccatt
     5341 atttactacg atcaatttga tcgttattgt cggaatttca ctagtcattt ataaaaaaga
     5401 ggggatgaag ggatgaattt taaacactcg tggacaagac ggttaaaata tgtttttccc
     5461 ataatgatga tgttaggtac attgtttggg ttaaaaacag ccaatgtctt tgctgaaaaa
     5521 gttattgtcg atccgtcaaa tccaatccag aacgtaaaga ataattttat tattccaaaa
     5581 gatgttccta atgcaaaaac aaatattact gtaaacggag cgtcaaaagt ttacaaatat
     5641 catgttgatg ccaacaaagg tggttttaca gacgactacg taggattagt ggagggaaac
     5701 aaaaatatac gctatccttc tttccaaaaa gaatacggtg aaacaaacct tgttttagaa
     5761 ggcgtaacaa ccaacaccaa agtcaatatt gactatggaa aaatcggtac gtataacggg
     5821 aaaaaagtca atatcaagct agttctatct aatattcact tatactcgga tacgttgccg
     5881 tggaatctac tagataacaa ctatacaaaa actcattttc gagacgatgg ctataaaaat
     5941 acgaatggtg caatgagtaa atctaaaaaa agaacagtac tttggatctc agacaatctt
     6001 ttctcaggaa ttgtttacca ttcaacacaa atgaatgtgc agctagtagc cacatatgag
     6061 gacggtagcc ccgttcaatt ttcaggagat acatttatca gttttaactc tttgaaccct
     6121 gcaggaggaa aaagcacgga tcttaaagga gaatatgccc actatgacaa aatgaatacg
     6181 acagattggt atgtcagaaa agatacggtt ctttcagaat ttaaatcttt ctacaacaat
     6241 ctgaacgtgg taggtggcca cccaggagga agctctaagc tgacacaagc ggataatgat
     6301 ttcaataatt tgcatgataa attaggagat ccgaagtttg gtcaaggtac tgtgtccttt
     6361 aaaatatctg aagcaaatcc gacgtttgtg attggttctt ctaatgttca aacctggttt
     6421 actttatctt ctgcgacaat ctttagtgtt gttcctgatc aacctgaaaa aacaggggtt
     6481 gataaaaatg gaaataacgt gaacgataaa atgttgcaag taggagacac gattcaatat
     6541 cgaatcaaac agaaggtgaa tcgattagga gtggatttac tagcggttta cgatcgattt
     6601 gagttaatcg ataatttacc aaaagaagta aattacgtcg atgcacacgt tgaaagtggt
     6661 acaaataaaa aattcgatgt atctggtgaa gtgacctatg acaaaacaaa acaccaggta
     6721 aaatatgcag cgaaagctga tacattaaaa aatcgaatga agtataacgg cgaaacttac
     6781 gaattagtga tcaatgtaaa agtcaatgaa ttggccaatc aaaatagtgt agccaaaaat
     6841 cagggaacgt cgatcattaa taaagtagaa aaggatacaa atatcattac cgtttatttc
     6901 cctaaaattc cagtgaaaga agtacaacaa aatggaaaag atgtaaacgg acgaaatgac
     6961 ggtaagaagg gtacgccgac agctccttta aacgcaggat ctgaagtaca atatctagtc
     7021 acacaaaaat ggcacacaaa aggcgtagac gctgcgtcag atcactacaa acaatttagt
     7081 attcaagatc caattgaagc tcgtttgaca tataaagaag gttctgcgca agtaatagat
     7141 aagagtaaag gaaaagatat tacttctgaa ggcacactaa cctatgatag caattcaaga
     7201 acgctgaagt gggaagcttc cgctgacttc ttaagtaaca atcttttaga tggacgagaa
     7261 attcagctga tatttacagc taaaactcca ttacaatcag aaaaaaatat tgataaccaa
     7321 gccgtagtag cagtagataa tgtttctaat aaaacaaatg ttgtgacaat tggggttgat
     7381 cctaacttgc cacaggtcat tgttcctaaa acaggttcta cacatttagt aacgatttca
     7441 gcggtcagct tactattact tgtgttagca acttttagtt atgcggttct gagatacatt
     7501 taaaataaaa aaacgaaaga atgaataaaa tgaaaaagtt aataatagta gttacttcct
     7561 tgattgccat gattgttatt ttagtcggat gtagtaatga aaaaaataaa caaactaatc
     7621 aagataatgg cgtattgaaa tcaggaacta tgtggaaaga agaagtaggt ggtcttgttt
     7681 ataatttgaa aattatagac gagactacct gggaatactc tgagagtgta tggcatccag
     7741 atcctgtaca aataacagtc aagaggcaaa aagactataa aggtttagaa agatacaaaa
     7801 tagtagattc agctggtgtt agggaattta taaacaaatc tgattcttta tttattgttg
     7861 ttccctatga gaagaatggc gtaaaaaaaa taatttttct tggatctagc aaggatgaaa
     7921 agcgaacgaa agagaaattg attcacgatg gatcacaatc caataaatat aagttacaaa
     7981 agactagcga gtgattgcta gtctttttat ttgtcctgaa ggaggaatca cagtggcaaa
     8041 agctaaaacg ccatttgaaa aagccgcgtc taaaatctta gaacgccgcg gtgtatctga
     8101 aacacagtgg aaacaagaag tccttgaaaa agcacaattt gacctattac ggggaaaaga
     8161 caaggactta gaaggatata tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat
     8221 tattaaacac taaaaggagc gaacaatttt atgtttgaat caattacaat gaatttttta
     8281 acacaaccga aagtagtagc tgcggttgat atttttagag cattacaaac tgccgcaact
     8341 agtttaaaaa acaatctgat gatttttgct gctgctgcgg ccgttgcttc cattgttatt
     8401 gggggtcttt tcttcctatt tggacgaaga ggagctgaaa atgggaagat gcacgtaggc
     8461 tatgtattga tgggggtagg agttatttta gcagcagctt ctattgtggt ttcgttattt
     8521 ggattgtttg gacaaacacc tcaaggatta taagaaagta aaaaagtagg agtaagaagt
     8581 agtcgatact ttttactcct tttttatgaa aggagaatac tcatgtactt tacgattgca
     8641 ggcaatacca aaacagataa agagttaata aaaaaagcaa cgaaggaagt aggaaagcgt
     8701 acttcttttt taccgaaaac aattaaatat tctgtcattg aaacggaaga acagctacat
     8761 gtgttaggga aagtactgga acacgaaagt cgatcttctg ttaagttgac tctcacgtta
     8821 catgacacag aaggaaaaat agagaaagct ggtacagaat acgtttttgg cccactggat
     8881 tatcaaattt cagaaggttt ctatcctaca ttgatggatt taatccgcct tgatgtgttt
     8941 aaagaaacgg atgaaactat gagtgtggaa gagtcttatc gaaacgaaaa acttttacaa
     9001 gttttagaag aagagttaga gagcgaccaa agaaaagtga atcaagggag tgaagtcgaa
     9061 gtaaatgaag aagtaccatg ggaacgacca atatttccaa agaaggagtc aaaagaaaaa
     9121 gagacagtct atgttgacga acaagctgat attccgactc agaaatcgat atttgaggaa
     9181 gagaacgatg tgatgggtca attggaggta gatccctttg aagaaacaat ggaggatgaa
     9241 gagacggccg aagtagaagt tgatccagtt gaagcgaatg aagagtcaac atggactgaa
     9301 ggggattctc aggaatatat tgaaccactt atcagtgaag aagtagaaaa aaacgaaata
     9361 gagatacaaa aggcaactgt atttgattat attttggatc aatatccgcc agagcatgaa
     9421 tggatgaaag aaaaaaacaa attattttta aatgagcttt attcgaaata tcaattaccc
     9481 caaacctatc aagcattttt agagagtaaa gaagaattaa tctcacaggg taaaggcaca
     9541 cttttagaac agttagagtc tgtccaatca acaaattggc atgagcttgc acaagaagat
     9601 ttattagcca cctttgaaga acgtcaacaa gaaacagatc aagaaattaa tgagtatgcg
     9661 acggaacagt cgtctaattg ggagaaagca aaagaggaac taaataaaga agaacagcga
     9721 gtgattgaag aagaagtaca aaaaattaaa gagcgatacg aaaagaaacg cgacaatgcg
     9781 tattccttgt gtgtagcaaa gatcaataat tttactcaga cgaatcaaga agcgttatcg
     9841 aaagaaaaag aaaacttgtt aaaagaacgt attaaagaac gaaaagaaga attttaccga
     9901 ggtttgcgta cagataagct aaagattagc aaagaattaa atgaacaact gaataagcta
     9961 tatcaaacaa cgactgaagt tcttatggaa aaatacgaaa agatccagca agaattacaa
    10021 gtgcaaattc caaaatggaa aaaagagtat gaaattcaac aacaagaatt gaaagaacaa
    10081 gaagaaaaac aacggcaaaa agaaaaagag cgcgaacaat tagaactaaa aaaacgtgaa
    10141 caggatcttg cggaacaaca aatggcaata gaaaaacaac ggttaaacca agaaaaggaa
    10201 aaagaagcag ctgctcgtaa ggaacgtcaa gaacaaatgg atacattgcg acaagctcag
    10261 ttaaattatc tagcacaacc tcaaccaacg ccttcagtag ctgctgttca aaccccaatg
    10321 aacaaccaaa caaatctaac tccttcacca cagcgttcct ttaacggatg gatggtggga
    10381 tgtattgcaa gtttaagctt acttctaggt ggaggaacag tatttgcttt taatcatatc
    10441 aatcaatctt cacaggctga ttctgtggcc acaacgacgt caatcaagga agaagcccaa
    10501 gaacaagcaa gaaaagagta tgaacaacaa ttagaagaat tattgaatcg taccaatcag
    10561 tcaacaacag agtcaagcat ggaaaatagc aaagagagtg attctagtaa ggctaaagaa
    10621 ggatcaagcg attcaactgt acaatcaaac acttccgaaa gttcagaatc aaatgaggtg
    10681 aaataatgcg tgttagagaa acaacgaagc gaaaagacaa acgattcaat ttagaaaaga
    10741 ataggtatct ttctcatttc tatcgctata ctccctcagg agaagagcta ccagaaaaac
    10801 atgacaaacg catttcgaaa aagatttttt atagtggact tgtatacctc cctttagagt
    10861 atttagtaac aagagtacca gaagttttca accgattgga aattgttaag ggaagcttac
    10921 aaggaataaa tctgtttcaa ttacaggaaa tgccacaggt ctttcatttt gattcagctg
    10981 gtttttggaa tccatttact cctacaacta gtttgggtac acgtttagca atttcgacag
    11041 tttgtgtggt tccagctgta cttatgggat tgaaaatgga catgtggttt cgtcctctag
    11101 cagatggaca aaaaggggat aatcgattaa tgaccttaaa agaaatccaa cagatttatc
    11161 cgcaaatacc tgaaacaaaa actacttttc caggttatgg aggtattcca atcacacatt
    11221 acaaaaaata ttggtacatt caaacagata ctgttaatac gtgtattgtt ggtacctctc
    11281 gatcagggaa aggtcagatt gaagtgttag ccaccattga caatttatct cgtgcagaaa
    11341 aacaaagttc aatggtcgtt aatgatccaa aaacagaatt atatgttggt agtaaagatg
    11401 aactagaagc tagagggtat gatgtatatg cctttaatat caccgatcca ctgcaatcaa
    11461 tgagtgataa tccattggca ctcatcgtga aatactggaa acgaggagac atagatactg
    11521 caacacagtt aaccaatact ttcacaaata cgatttatta tgatgccaac gcttcagata
    11581 acaaatactt taacgaaaac gcgcagaaag ctgtcaatgc gcttattttt gcgttgttag
    11641 aacaagctga tcaaacagga gattactcca aattgacacc gaataatctc gttgagcttc
    11701 tttctgagat tggcggtttt aattattatc cagatccaga caatgaattc aaacagttga
    11761 atgccttaga tgaatttatg aatcagttgc cacctggaaa cattgcaaaa aaacaatatg
    11821 gggcaacgaa aattggatct gataaagcga agggaaatat tttatcaacg gcaatcacgg
    11881 gattgaatcc atttactcta acgaaaattg caaagatgac ttctcaatca acgattgatt
    11941 ataaatcggt tgggtttcca aaatacttag atttgaaatt acatgaaagt cttttaaatc
    12001 aacgagtcgt agtagaattt tatcataagg gaaagaaatt tcatgaagaa cgtgtcaaag
    12061 taggctataa aggattttgt gaaatcaatt ttgattgtca tttagttgca ggtgatcaag
    12121 tttgtttaaa atacgatcat caaggaaaag aatatgtggc ttggtatgaa ttttctcaaa
    12181 gagtattgaa agacgaagag ggtaatatcg tttatcggaa aaaacgagga gaaacccatt
    12241 tgccagaatt agaaaaagaa gccgttctaa cattagatga ggagaaaagt aacttattag
    12301 tagagtctat tcggatgcac tataccgata aaccaatggc tatttttatg cttacacctg
    12361 attatgatcc atctaaccat atcattgtta gtatttttct tagtcagtta tataaagaat
    12421 tatctacgca atgtgttaag actaaaggag ataaatgtca ccgcaggatt cattttattt
    12481 tagatgaatt tgggaatatg ccaccaatgg ataatatgga aggaatcatg acggtcacag
    12541 ctggccgaaa catgttgtgg gatctgttta ttcaatctta tcagcaactt tatgcgaagt
    12601 atggagaaca aaacgcagcg attatcaaag aaaattgtca gacacatatt tatattatgt
    12661 cgacagatga taataccatc gaagaatttt ctaaaaaagt ggggaataag acggttgaac
    12721 aagagaacag taccatcaat tcattaggta tgaatactca tatcaatcgc aatgttgatt
    12781 cagatcgtat cttaactcct gaaagaattt ctactttttt agaaggtgaa acgattgtac
    12841 tcgctccttt aaaacgacaa gatttgaaag gtcataaaat acggccgtat cctattttta
    12901 atcatgggga aacgaatctt ccttatgctt atcaatatat tgaagatttc aatccatcgt
    12961 gggatatcaa tgatatagac atacattgta cacatgcgga cttggatctt aaggctttac
    13021 aaattgatta tgattatttc ctaccagatg aatatgctag aaatctctat catggactgc
    13081 atgatcaatt agaagaaaaa aacgaagaaa atatgtttta taaaatcgtt caatctcttg
    13141 agaatgagac ggctaaaaaa ttgttaattc aattttacga agaacaagca gcagatcgac
    13201 ttcaagaata tgttgaaaag ttgatcaaaa ataaagaaat ttctgaaatg attgggaaac
    13261 ggttgttatt ggaatctgaa aaggtggtga aagaatgatc attggaggaa ttttttctgg
    13321 catagccgac tggtggtcag gcttattcgg agaaggggat gcaaacccca aaaccgtaac
    13381 gaaagtctta caagattatg gtaattatct gcagtatcaa gatgtattta gttggatttg
    13441 gaacactttt ctgtggggat tgattaaagg attatataat ctcaatactt tactagaaaa
    13501 aaccatttat caaagctttg atttaaaaga cttattgaac gccgctgggg taaatgcact
    13561 atttcaaagt ttgattagta aggtattggc tcttttttgt gtcgtcacat taatttattt
    13621 aggcttgaaa ttttttatga gtaaacaccc accaaaagtc aaaaatatct tggttaattt
    13681 atttatggcc atgatcttga tttttggtgg gagttcttta atcgatgaag ggttaaatat
    13741 cagtaaaagc ttttacggag acgtcactgc agcaaataaa gcagataaaa cgggttcacc
    13801 tgcttttcaa attattcaaa ataatgtgat cgatgtcagt acattactag caactgaccc
    13861 gaataaagta gaatccctgc caacagacaa aagaaatgct ttaacagcga aaaattttaa
    13921 aacagcgaat atcaatggga ttattactcc taaacaagct aaagaaatgg cggataaaga
    13981 taagagtggt ttatcagatt tacaaaagga tcggttaaga gcgttacaat accgattgga
    14041 actagatgat aatgggaaag aaattcctgt tcaaattagt gacgaaggct tagcaaaata
    14101 tgtctatact tcagggtatc gtcgatacag tagtaaacca ggtattatct tagctggtga
    14161 atcttctttg gcggtggcct atttatttat cctatttacg atcgttactt gcattattga
    14221 gctggtattt aaaaaattct atttagtgat tgccgcgtca acggactttg agacaggcca
    14281 acggatgaaa agtgcgatag aagatatttc tcaatccttc ttgttattgg cgtttacgat
    14341 tttagaatta cgaatctata cattaatgct ttcaggtatc ggtgatttgc atgcggcagg
    14401 aaagatcaat ggattcttgt atgttgttgc tttaattgtg ctaactattg cgctattcaa
    14461 aggctctcaa tcggttacga agattttcgg tgttgatacg agtctgaaaa acggcagtaa
    14521 ttctcttctt agcatgtttg ccttaggaaa tattgcgaaa aatgtgggta gcggagctaa
    14581 aaaccttgca agtgctggta agagtggttt aagccattta aatgatattc gtaaaaatgg
    14641 atttggccat cgaaaagatg ttacccctga taacggggaa gaacaatcag acgataaagc
    14701 tacaactgta cctaatagta agaaaacagt ttccgaaatg ttcgggaaag cgaaaaatgg
    14761 tgtttctaaa gccgcagaag gtcttggtta cgtcaatgaa cgtgggttaa aaggaacagc
    14821 tgaagatctt acagaaaaag ccaaagacac cttagaagag aaattagacg gcacgagagc
    14881 taaagaattg gctgaagctg tgaagaatcc atccgaagca ctagaaaaac aaaaagaaaa
    14941 agcttcagaa gtcaaagaag gactaaaaga tgcgtatggt gaaggacaag ttaatgcagc
    15001 agtaaaagct aatacaacaa ccgaaaaaga aaatcaagaa ggtatagtga ttccttcagt
    15061 caaagatcac caagaagcgt tgcactctaa tgaaaattcg attgaagaga aaaattccat
    15121 agaagaaaga aattcagaag aaggaaaaaa tggacagtta ccaaaaactg atccagaaca
    15181 atatcgctat aaacctaaca gtgaccttga aaatgagaag cgaatttcag atttatcaaa
    15241 agtaaatcaa gaagacaaag cagaaaatga gggacagtta ccaaaaactg atccagaaca
    15301 atatcggtat agatctgtta actccgaaaa tgaaaaacgc atttcagatt taccaaaacg
    15361 aaatcaagaa gtacaaacgg atgaggattc catcgttctg ccaaatgata atggaatcga
    15421 agttggaact gaaaaatcaa cgaaaattgg tttacctaag gcacaaaatt taccaatgaa
    15481 agatagtcgt ttgaatcaat tcaaggagaa tgatcaaagc tttgttcacc aatcaactgc
    15541 aggtactgtt caaatgaaac caagtcgttt gcctgaaaat ggaaatctga caactgtttc
    15601 ttacaattta tctgaaagtg gtgagacagg gaatgcgtcc gttcaaaatg ttgtgacaag
    15661 agaagctgca ccaaaaccta ttcaaaacgt tcatacaggt tacaagccag caaatgtggc
    15721 atttactgca ccaacaaaaa taaatgtgac aagagaaact aaaaacagga acaatgcatt
    15781 gaaagaacaa ctattgaggg atatcaaaca ggatatcaaa ccataaaagg cctacaagtt
    15841 aggcctttta tttatatgaa aaggagaaat caattatgga taaatatata aacatgaaaa
    15901 accctccaag atttagtgga gaatggaagt ttttcgcttt tttcttttta gatctattaa
    15961 cgcttggtgg ctgctttttt tgggcgaaaa tggtcaataa tcttgtccac ttaccactct
    16021 tttttgcact cttgaattat ggcttatgga ttgcgatagc gttagtgatt gtttggcgac
    16081 cctataataa cccaggtcaa cgacaaattt ttgcgattat cgagtctatt ttttttgcgg
    16141 acaagaacca ttatcatgcg ttagatccta accgaaatta tcatggtacg tataaggagg
    16201 atgaataaat gcgagtcaaa ggacaaaatt cagttgaaag gaaatccatt ttgcagtttg
    16261 gaaaaccaga agagcgctct atcttggact tatttccgta taaatcctgt acagaagagg
    16321 gagtcttaat tactagagaa gatcattttc aacgttatta tcgtgtagtt tctacagacg
    16381 tggaaggatt aaatgaacaa gagaaactag aacgaatgaa tcagttgacc accgtcatgc
    16441 gtacgtatgt gccaacaatt aagttagtta gtttgaccac agagacggat ctaacggaac
    16501 aaatcgtgca aaagcggcaa ttattagata aaaatcgtat ggaacagtcc ttaggaagaa
    16561 atctacaacg attaaaaaaa tatgaaaaga aattagtcga agaaatccag gaattgaaac
    16621 gagcagaaca agaacgtcct gacttaagct tctttttcgt cattgaagga aagacaatca
    16681 aggatttaca aaccagaaac cgtcagttaa tgcgatctag tggcatttta gggttaaaac
    16741 cactctacaa aaaagaattg atcaagattc tgtatcgaat gaacaatatg aatgatgagt
    16801 aggaatggag aagagagaat gaaatatccg ttgatatggt tagaaaaaga tgttccgaag
    16861 gaagagacca ctagaaaatt tcctcacact ttaagcctgg gtaagttggg aaaagggcaa
    16921 tcttttaacc aagtaaagaa tcaaacaaga agaggtgact gtacatgtta gaagcaatta
    16981 aaacagcttt ttcaccacaa aatgatcaaa aagtacttga tccattaaag caactaggaa
    17041 atcgggaaat agaaatttta aaatccaaag ggtatgattt agatttttta aaacaagtga
    17101 tgccacaagg tgggttaaat tttgatgaag aatatgtgac gtatggtaat ggttattcac
    17161 gatgtgtgac agtttatcac tacacaaaaa atcctacgct tttttggttg gccaatctca
    17221 tgaacaatcc tcatacagtg gccacactcg atgttagcac agatgaaaag caaaaagtga
    17281 ttgatcaaat caatcgtgcc ttagatgaat taaatgatcg atcagataat gaacgaaaag
    17341 cgactgaccg aaataaaagc gcagaagaat acctggaact agcggaatat gctcgtaaat
    17401 tgacttctaa tggggaaatt tctaagcaag tcaaagtgag agtacatgtt tacggaaaca
    17461 cgattcaaga agtagatgaa cgagcgcagg aactgatcga aaatctaaaa gggatggatt
    17521 atcgtgcggt gacttatctg cataaaacca aacgagattg gcaatcgatg tttaccatgt
    17581 tcgatgaaca agctgaatgg ttcggaaata tcaaagggca atcactacca tcgttaaaca
    17641 ttggcggagg tttcccgttc caccaccaaa cgctaaaaga tccaggaggg acacaatatg
    17701 gggaaaccat gacaggcggc ccatttgtct ggaatgcgac gtataaaaat agtgtacggt
    17761 tgtctactaa taccttgctt ctaggaatga tgggagctgg taaatcgacc gttcttaaaa
    17821 tgatcgcgga agcccattta gctgcaggag actttatttg gggctttgaa aagggaaaag
    17881 actttattcc tttcttaaag gaatataacg gtattatggt gcgtttagac ggatctgacg
    17941 gaatgatcaa tcctttagag atatttgcca cacggacgta tgatgaagca tccagtttat
    18001 atgacgatgg atcagtcaaa gatttgaaga tcaatgaagc agcgtcctat caaacacact
    18061 tagacaaagt ggtctatcag gtacagttag tgagtcctca gctaaaagga acgatgaaag
    18121 cagaatttaa gacctactta aatcgttttt atgaagagta tggaacagta ccacgcggct
    18181 ttacttcctc aaattcgcgt tcaaatacgg agacgcaagt cacaggtaaa gatccagaag
    18241 cttatccgac gttcaaagaa tttttagact ttttaggaca actggaatta ccaggtgctt
    18301 cccaagagaa aaagaatcga aaagaagaaa tggaatccat cgtagaatcc ttatgtgaga
    18361 cgtatggcat gatttttgat gggcatagta cgattcgaca ccttgaccaa caacagttgg
    18421 tcttttttga cattgactct attacaggct tagatcgagg ggtacaacaa tgtcaaatgt
    18481 acatggctat gacgttgatt tggaatcagg cattgattca aggaagaaga caacgacgtt
    18541 taattaaaga aaaacaaatg gaagaacaag acttcaaacg cttcttggcg atgattgatg
    18601 agtgccataa tgcgattaat ccagatttta ttgaaacggt aaattatgtc acaaactttc
    18661 aacgagaaat gcgtaaagta gaagcaatga ctgttttagc tacacaatcc ccacaagaaa
    18721 tggtgccaga aaatatgtct tctgataact tctcgaaact gaagaaagtc tttgaatttt
    18781 cttctacgaa gatctttatg cgtatggatg aatctatttt acgtcatata gaaggattag
    18841 tgggtaaatc aatgacgaac tcagaattag aatccattcc tcaacaaaat caaggagacg
    18901 ctgtgatcaa ttttggctca aaagaaacca ttcgtgttca ttttagtccg aacaaacgtc
    18961 aattaaaatt gtttgatgga ggaaaataat ggaaaaccaa aatgaaagtt taatcaaaca
    19021 gtatgttaag cgtcgtgcaa agcggcgctt atttttgtgg gtgtttggta cttctgcagg
    19081 tttgattact attttgatca ctgtgtttgt gaccctattt ctaatacttg cggcaggttc
    19141 gattgataat tcggattcag attcaagcag tggtggcgaa gcttttacag gagaatattc
    19201 ggaaggctta ccgatttata aagaaatcaa aggaagaggc cctttttctg atgagattgc
    19261 gcaatatgct gtaggtgcag cagtgaaata taaattatta ccaagtgtga tcctttcgca
    19321 atacggttac gaatcagcgt ttggtacgtc ggcgtccgca agaaatgatc tcaactattt
    19381 tgggattacg tggtttgatg ggtgtctgtt tcctaaagga actgcgcgag gaatcggtgg
    19441 tattgaaggt ggctggtaca tgaagtttcc caactcaaaa gctgcatttt cctattacgg
    19501 atttatggta gccacacaat ccaattttaa tgcttgtgtc ggaaataaaa gccctggcgc
    19561 aagtttattg atcttaggac gaggcggtta tgccgctgca ggaattactg aagatagtcc
    19621 gtattataca ggttgtatgt caattatcac ttctaataaa ttaaccgaat atgatgaatt
    19681 cgccatcaaa cattggggtg aaggtggcaa taacaatggc acaattactg gtgaatggac
    19741 gaatccattc cctggcagca gtttagataa aagttccttc agcggtggtc aattatttgg
    19801 aacaaatcca ggcggtgaat tccgtccgaa tggcttccat gatggattag actttggttc
    19861 agttgatcat ccaggaagtg aaattcacgc ggtgcatgga ggaaaagtcg tgtacgttgg
    19921 caatcctggt atttcaggtt taggtgcatg tgtgatcgtg attaattacg acggtttgaa
    19981 tatggtatat caagaatttg cgaatagtac aggaaattct cgtgtgaagg ttggcgatca
    20041 agtgaaagtt ggtcaagtaa tcgggatacg agatacagca cacttgcatt taggtttcac
    20101 tcgaatggat tggcgtcaag cacaaggaca cgcattcaca gatgatggta catggattga
    20161 tccattacca tttttgaata gcagcaaaaa atagatcagg agaaaaaata tggaaaataa
    20221 aactttaaaa atcgtcttaa cagctgcaat tagcgttagt ttaatcggca atatcgcgtt
    20281 gttttggcag ctgaaagaag aacaagagac aaataccttt aaaattgaag aagtggctaa
    20341 aaacgcgtct gagaagctca aaaaaaattc ctctgaggca caggcgaaga tcgacaagtt
    20401 aaatcaaacc atcaatgaga aaaaccaaga aatcgaacag ctgaagcaac aagatggcac
    20461 aaaagcaaaa gaagaagtaa ctgaagcaca aagtaagacg gcagaagagt tcggtaaatt
    20521 agccattgat aaatcattaa gcagaaatga attaacggaa aaactaaaag atgtcgcaac
    20581 ccaagaagtg attgacaaat taagtcctgc agacgatgat caccaacatg atgattacgg
    20641 aagttactcc tttacattag gtgacgtgca aacttacgct caaacaagca gtgtaaaaga
    20701 ggaacaaaat tttgtcgtat ttgttgatta tacaatcggc aatcctcaat tcaaagatgt
    20761 caaaccacaa aaaataaaag gtggattaac tgtcactgaa aaacaggtag atggtcaatg
    20821 gaaagtcact gactttagtt atttcactcg ttaggaggaa gaaaatgagt aagaaaaaag
    20881 gagaaagaca acgtttcaaa aaacgaaaaa gttatcttag atggctggga atctttatga
    20941 ttctcggatt tttgattctt gctagtccga tttacacgca tcagaaggta gacataccag
    21001 atgaagtaag cacgaacgca tttttaaaca cgaaggaact aacgatggtt tcaaaagaaa
    21061 aaggagcgaa ccagcaatta gtttttgaat ttgcaatcga cgatgaagat caaagcttat
    21121 taaaagaact ggctaatctt aattatcgcg tagaagtaaa gacagctaaa ggggattatc
    21181 aagcaataaa agccaaagtg attaaggtgt ctgatgatta ttttgcagtg aagctatcgc
    21241 atgtaccaga agaatatatt gctatgcgat taaccattat tcctgaaaaa attgatccaa
    21301 aggtggatat gcaagaacca caagatctga tttattacgt tcacgaagat aaggttaaag
    21361 atcaagtgaa agatgaagat tatgaacaac atgcgatcaa ttacaaagtg aaaggataca
    21421 agaaagaaca aaaagcagct caaaaacaaa tggaatcttt ccaagcaacc attgatttga
    21481 atgaagaatt agtgaagaag ctaaaagatc aattgcctta tcaagtcgca gatgatcagg
    21541 aaaatactga aaacaagatt aatagctacc agcaagaaat tgaaacatcg aaaacgcaaa
    21601 tgaaagatca agaagagatc attcaaaaac ttcaagaaaa aattgatcgt atgacaaaag
    21661 aaaagattta gaaggacagg tggagtgaaa aaatgaagcg aacaaacttg gctgacaaag
    21721 atactttcgc tgagcagaaa gtattgatta aagcctatct caaagttgta aaagctaaag
    21781 aaatatgtcg agaagtgaat ttatctaata caacaatatc tgagttgaag aatggtc
//
LOCUS       DASHXG010000043        21266 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.043, whole genome shotgun sequence.
ACCESSION   DASHXG010000043 DASHXG010000000
VERSION     DASHXG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.043"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(37..570)
                     /locus_tag="U2R59_001923"
     CDS             complement(37..570)
                     /locus_tag="U2R59_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEM8966307.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(664..1842)
                     /gene="mutY"
                     /locus_tag="U2R59_001924"
     CDS             complement(664..1842)
                     /gene="mutY"
                     /locus_tag="U2R59_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEM8966308.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(1835..2632)
                     /gene="recX"
                     /locus_tag="U2R59_001925"
     CDS             complement(1835..2632)
                     /gene="recX"
                     /locus_tag="U2R59_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEM8966309.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            2739..4121
                     /gene="rlmD"
                     /locus_tag="U2R59_001926"
     CDS             2739..4121
                     /gene="rlmD"
                     /locus_tag="U2R59_001926"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEM8966310.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4295..4873)
                     /locus_tag="U2R59_001927"
     CDS             complement(4295..4873)
                     /locus_tag="U2R59_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HEM8966311.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5195..5665
                     /locus_tag="U2R59_001928"
     CDS             5195..5665
                     /locus_tag="U2R59_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HEM8966312.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(5773..6999)
                     /locus_tag="U2R59_001929"
     CDS             complement(5773..6999)
                     /locus_tag="U2R59_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8966313.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(7753..7953)
                     /locus_tag="U2R59_001930"
     CDS             complement(7753..7953)
                     /locus_tag="U2R59_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8966314.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8087..8695)
                     /locus_tag="U2R59_001931"
     CDS             complement(8087..8695)
                     /locus_tag="U2R59_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEM8966315.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(8780..9250)
                     /locus_tag="U2R59_001932"
     CDS             complement(8780..9250)
                     /locus_tag="U2R59_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEM8966316.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9298..10212)
                     /locus_tag="U2R59_001933"
     CDS             complement(9298..10212)
                     /locus_tag="U2R59_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEM8966317.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10358..11161
                     /locus_tag="U2R59_001934"
     CDS             10358..11161
                     /locus_tag="U2R59_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEM8966318.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11339..12286
                     /locus_tag="U2R59_001935"
     CDS             11339..12286
                     /locus_tag="U2R59_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HEM8966319.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(12354..12647)
                     /locus_tag="U2R59_001936"
     CDS             complement(12354..12647)
                     /locus_tag="U2R59_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HEM8966320.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(12675..13340)
                     /locus_tag="U2R59_001937"
     CDS             complement(12675..13340)
                     /locus_tag="U2R59_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEM8966321.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(13480..14112)
                     /locus_tag="U2R59_001938"
     CDS             complement(13480..14112)
                     /locus_tag="U2R59_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8966322.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(14119..15186)
                     /locus_tag="U2R59_001939"
     CDS             complement(14119..15186)
                     /locus_tag="U2R59_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEM8966323.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLIAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(15183..15914)
                     /locus_tag="U2R59_001940"
     CDS             complement(15183..15914)
                     /locus_tag="U2R59_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEM8966324.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(16083..16562)
                     /gene="greA"
                     /locus_tag="U2R59_001941"
     CDS             complement(16083..16562)
                     /gene="greA"
                     /locus_tag="U2R59_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEM8966325.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(16698..17873)
                     /gene="mltG"
                     /locus_tag="U2R59_001942"
     CDS             complement(16698..17873)
                     /gene="mltG"
                     /locus_tag="U2R59_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEM8966326.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            18077..19246
                     /locus_tag="U2R59_001943"
     CDS             18077..19246
                     /locus_tag="U2R59_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEM8966327.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(19513..21147)
                     /locus_tag="U2R59_001944"
     CDS             complement(19513..21147)
                     /locus_tag="U2R59_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966328.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         6554 a         4154 c         3341 g         7217 t
ORIGIN      
        1 aaaaatctct cactggctta ctgttctttt ttgtgtttac ttacgcgaca attgcttgta
       61 acggttatac caaatatcaa tatagccttc cgagaacggg ccatctccat tattgatcca
      121 gtcaaccaga atcttcacat tttcttttag gatgaagtca atatcgttcg ggtaattcat
      181 cattttgctg tgcatctcat attcatcgac atccaatagt cgtttctcgc cgtcaggaaa
      241 taccttgata tccaagtcat agtcgatata tttcaaggcc tcatcgtcca gcaaaaaagg
      301 tgaagctaga ttacaataat aggaaacccc cttttctctg atcattgcta ttacattgaa
      361 ccagtatttt ttatgaaaat aaacaatcgc tggttcgcgc gttacccatc ggcgtccatc
      421 agattcagtg actaatgtgt gatcattcac gccgatcata gagtgttcgc ttgtttttaa
      481 taccatggta tctcgccacg ttcgatgcaa tttgccgtcg tgcttgtaac tttggatcgt
      541 cacaaactct ccttcttttg gaactcccat agcaaccctt ccttaagcag cattttgtgc
      601 tttgtgtttg ggtgttcatt acaccgacat cataattatt atatcaataa aaatgagctt
      661 tgcctagaaa ggattcctat tgtttcgatt tttctctaac tgatctacca gtttcatttg
      721 gaccttagga aaaacgaccg aatcaaatgc atcaggcttc aaccacttcg aagttttgtt
      781 ctcggtaaat tcttgttctg ctccctcggt tgcccgtccg taaaaaagga gaacatgcca
      841 tttcagatga ctaaaaatat gagtaacttc tcctaaatgt cgtgtctgcc aaacaaagag
      901 ttcctgcttt tcaaatggga gattttgctc ttcttctgct actaggtcat caaacagatc
      961 gatttctggc tttgtttccc attctttttt caatcgctca tactcctctt gtgtcacttc
     1021 catcattgga aatgtccaca tattcgccag caatttttgg ctatctcttt cttcaaaata
     1081 atacgctcca gaatgatttt gaagagctgc actgatataa taaacgtctt ttggctttgc
     1141 tttttttgtt tttacaggaa aactcgtttg gattcctcgt ttgttagcta aacaaaaggc
     1201 ttggatcgga caagtctcac actttggaga agttggtgta cagatagctg aacctagatc
     1261 catcattgct tggttgaatt cacctggatg cttttcatca atgattttcc gcatcgcttc
     1321 atcaaagatt ttcctgctag aagcttttgc gatgtctgct tcaatgcaaa acaatctgct
     1381 gactactcgc atcacgttgc cgtcaactgc aggttctgga agtccaaatg cgatacttgc
     1441 aatcgcgcct gtcgtatatg gtcctattcc cttcaatgag ctaatttctt caggcgtttg
     1501 cggcatttcc ccatcaaatt ctgacatgat ctgtttagca gcagcttgga tgttccgggc
     1561 tcttgagtaa taaccaaggc cctcccatgc ttttaaaagc ttttcttctg gagcatttgc
     1621 tagctcttca attgtaggaa accattccat gaaacgataa aaataatcga tcactgtgtc
     1681 tactctggtt tgctgaagca tgatctcaga gatccagata cgataaggat cacgattata
     1741 gcgccaaggc aggtttcttt tttcttgttc ataccattga atgaactgat cttgaaattc
     1801 ttttgtttct ttatctgtcc atttttccca ttctttattc actttcctct tccttttccg
     1861 taatgaatcg ctggatcata tccaaatcaa atcctttttg atataagctt tgctttactt
     1921 ttagatttct ttttttaggt tcaaacctta aatttcttcg ccatagttta tctccttgtt
     1981 tgactaaata atcatattct atttcttgat ctgcttcttg cggaagatca gctatcgctt
     2041 gttggatcac ttcttgagaa aagcctttcg tcatcaatgt ttgttggatt tttctcaata
     2101 attctttttg gctttttccg tgattttttc caaacgcttt ttcggctgtc tgatgtgcat
     2161 tttgaacttg gtcttcaaat gtatattggc tgagcgcttg ttcaatgatt tcaggtttca
     2221 aacctttttg ctgcatctgc tgcgctaatt tctttggtcc tttgtcactt aagcgcatat
     2281 tcgtgcgcac ataactttcc ccatagacca aatcatcgac aaggtccaat tcttttaagc
     2341 gggctacgat tttatttcga tcttcttgaa ggatttcctt ttcttttaag tatgttcgga
     2401 tttctttttc cgatcgcaac tgataactta agtaattcat tgctaggtga aaaccgaaat
     2461 cagctccgct actcttcttg atctcttgga tagtttcttc gtctaattcc cgtcctttta
     2521 ataatcgata gcgtactaat acatcttcag atacttgtaa agcttctcct tcagataaat
     2581 ctacgcgata gaaagggcct ttgcctttac tgattctcgt aacggttaac ataaacatcc
     2641 tcctcgaaca tatattctct atcataccac agaaaatccc cgtaatcagg tattatatgt
     2701 tagaataaac cacagaaaaa agaaaaaggg agatacttat ggcagaaaca attgtcaaaa
     2761 ctggacaaac ggttcctttg aaaatcaagc gtttaggcat aaatggtgaa ggaatcggtt
     2821 atttcaaacg gttgatcata tttgttccat atgcactacc aaaagaagaa gtactagtga
     2881 aaatcacgaa agcaactcct cgctatgcag aaggagaatt aataaaagtc aaaaaaacaa
     2941 gcaaagatcg cgtagtggca ccatgtcctg tttactatga atgcggtggc tgtcaattac
     3001 aacacttagc ttatcaagct caattggatt ttaaaaagga tctgcttttg caagcattgg
     3061 aaaaattcaa accagcaggc tttcgatctt atcaactttt gccgacgatc gggatggatg
     3121 agccttggca ttatagaaac aaagcacaat ttcagttacg aaaaaataag cagactcaaa
     3181 aaattgaagc tggtttatac gaagcaaact ctcatcagtt agtccctata acagactgct
     3241 tggttcaaga acctcgaaca caaaaagtaa tgaatactgt tgttcaacta ttgaataaat
     3301 ttgatgcacc catctatgat gaacggacaa acagtggaat cttccgcaca atcatggtta
     3361 gaatcggtgt taaaactggg gagttacaag ttgtttttat tactcgcagt aaaaaattcc
     3421 cgcaaaaaaa cgcaatgatc cgtgagatca atgaacgact gcccgaagtt gtttcaatca
     3481 tgcaaaatgt ccaggcacaa aaaacgtctc tcgtgatggg ggatgaaacg atccacttat
     3541 ggggaaaaga agccattgaa gaacaaatca atgaagtgac tttcgatctt tctcctcgtg
     3601 ccttctttca actcaatcct cagcagaccg aattgcttta tggcgaagga atcaaagcat
     3661 tagatgtcca gcctaatgaa acgatcgtgg atgcttattg cggagttggg acgatcggct
     3721 taagtgtagc aaaacaagcc aaagaagtac ggggaatgga taccgttcct caagcaatcg
     3781 ctgatgcaaa aaaaaatgcg gaaagattag gatatcacaa cactcgatat gaagtcggga
     3841 cagcagagca agttctgcct aaatggttga atgaaggttt tcagcctgat ggtatcatcg
     3901 tagatccacc acgtacgggt ttggataacg cattgatcca atcattattg aaataccctc
     3961 caaaaaaact tgtttatatc tcctgtaatg tttctacact tgccagagat ctggttaatt
     4021 taagtaaaaa gttcaagatt gaatatttac agtccgtcga catgtttcct cagactgcac
     4081 gttgtgaagt tgtcgtgaag atgacgagac tcgctgacta aatgaaagag gttgtgaaaa
     4141 agtctgccct gtatcaagta ataagaacag ccaaacaaaa atagctcttc atgttttatg
     4201 aatactgtac ttgtgaccga agagttaaca ggaggacact atttatttaa aaaaagggtt
     4261 gtgacatagt ttttgtcaca gccctttttg attattattg gatattcacg tctatcactt
     4321 gataaaatgc atttgtcgta tcgctgatat tccatactgc taaaatcaca ttatatcctt
     4381 ttcgatcctg cggaagtgtg atcgtttggt tgactgtttt tggtggaaca gttgctttgt
     4441 cgtctatttt tgtgatcaat tcaaaatcac taaatttcaa aggttgatta ggattccaag
     4501 ttggtttggt aatgtagtaa tcccaagtac ttgtccgatg ttgtgctgtt aaattccaag
     4561 taatatttaa tgttcctgga ttaaccatgt ttttatgcca tctgttagat gtctgttcat
     4621 ctaaaggctc aaagccgctg actcctgcac tagcaatttt tccatcaatg aatgtatttt
     4681 tggtagcttc gatactttgc ggttcccatt gtgctcttcc gacattttga tttaagtttc
     4741 ctgctgctga tgttcctagg tatgcacggc ttcctggaga agtaatataa ccatgcgcaa
     4801 aacctggaat gctaaaaccg aacaacccta aactaactaa cccaataaac aataacgtac
     4861 taatcttttt catgtagaaa cctccttcat ttgataacca cattgtaaac gctttattgt
     4921 attaacacaa acattatgct tttataattt tatgttgaag taaaaaaggt gaaaaaagta
     4981 agatgcagat tataacagaa gtagacgaga aaagtacaaa tagaaaacat gagaatcaaa
     5041 tcatatgatc tttttcaaaa acatcattca tataaacaaa tgttcaactt tttaataaca
     5101 acaattatca atttttttct tacttcacaa actaaataca ggtcttgctg tgagccttca
     5161 tggtaaacta atattataga aaggagttag taaaatgaag atgataaaag atattcgttt
     5221 ttgggtttgt gttataggaa ttgtcatatt aggcttttta tcagggttgc ttagcggaaa
     5281 tcccggaaaa tattactatt ctttgcaact tccaccattt gcaccaccta gctggatatt
     5341 tgggccgatg tggaccttac tgtatatatt gatgggtatt tctctttatt tgttacttaa
     5401 tcacaacaac aaaaaacagc gaaacaatct tgtcggtctt tttgtgattc agttcatttt
     5461 taattttata tggtctgctc tattttttaa tttaagaaat attttcattg cagcaatcga
     5521 tattacactt ttagttattt tcttgtcagt gcttatgtat cagttgtggc tgcatcatcg
     5581 cctggcaatg tggctcatga ttccttatta tttatgggta ctattcgcaa ctctattgaa
     5641 ttattcaatt tattttttaa actaagcgct aaaaagagac gtcctgtaat ttaacacata
     5701 gaaaaagtgc cacctaagtt agattttttg tctaatttag gtggcactct ttattaacca
     5761 aactattttt ttctagtacc cacttgttgt tccatactca ttattctggt cataaccata
     5821 accattttgt tcctgtccag cgtaaggatc ataactttga gtatcttgac ttggtgtata
     5881 gtactgactt gtatcttctg tttgctgata ataggtattc ggatcttggt actgatcata
     5941 tgtgttttct gaataggaag aataatcggt gtacccttca ctattcgatc catcaccgtt
     6001 tgtcgaatcg ccatcttccg aatcatcaaa gaacatcatt gaagcattct catttttcaa
     6061 attaggtaat gtatcgcttg tttttatatt taattgtttc ttcagttcat tttggatcga
     6121 aagaagatca ttttttccta aaatttgata gtagatatca ttgatcattt gtccttcgcc
     6181 ttgcaactgg tcttgtttga ttgtttcaaa cgccggggtg tagttcgtcg ctacatcaag
     6241 catgtcatcc caatctaagt ccgtcgtcac attgttctca actgctttta aaatttttct
     6301 ataattgctt acgccatcta aacttaaaac tttattgacg attttcgtca ctacttcccg
     6361 ctgacgacgt tgtcgaccga tatcgccttc tggatcttcg tgtcgcattc gagaataggc
     6421 taaacctttt tctccattca atgtttgttc acctactggt acatggacac catccaaagt
     6481 aaagtcaatt ttattattca ctttgatgcc accgaccgca ttgatcaaat cttccatgcc
     6541 atccaaattg atcgttacat aatgatcaat aggaatatcg agcagttgct caattgaatc
     6601 catggccatt tcgacaccac caaatgcgta ggcatgattt aatttatcta ccgttccata
     6661 acctacgata ttcgtataaa tatctcggtc caaactgatg atcgttgatt ttttttgttt
     6721 cggattaact gttactacca tcatcgtatc agaacgtcct tgttccgttc ttcctaatcc
     6781 accggtatct aaacctaata gcaaaaccga aaaaggttct ttgtcatcaa tgcttactct
     6841 ctcagaacgt ttggaggata ttcgattaga gtttttagaa attttgttta ctgtttggct
     6901 cgcttctccc ataaatctga ttccgtatgc tgataatccg gcaatcagca aaacgaatac
     6961 ccctaacaag gttaatagaa ctttttgcca tcgcttcata atacacctct gtttcacatt
     7021 ttctaaaata ttgtctcata taactgttca atcagcaaat tcacttttta atcataagaa
     7081 aactttaaaa aacatttttg tgtaacgatt attatttttt aaaatttctc aaaattctta
     7141 actatcatac cataccgtga aaaagatcga aagaccgaat acacgcagtt cgcaatcgtt
     7201 ttatcttttt ttatgtattt tttccagaaa aagcgaacaa caaggtattt tccaaataat
     7261 cgtgcagtaa aatgatcgca catacctttc ccatcttttt aacagtcttt gcctaccgtt
     7321 cagattatca ttcgatttca cgacaatttc ttcctatgac tggtcctttt gttaaaccca
     7381 tcttctattc gttttatttc cagctcactg catggctctt aaaatgactc gaactagtga
     7441 ttgcattacc atcatctttt aatggataga tatgctcctc ttcaaagtaa aacgattttc
     7501 ttttaaagta atagaattga catggtaatg agtatgtata ctagtggttt cacaaatggt
     7561 cttttattca acatccaaaa actgaaattt ctttaaaatc cattactaac gaagaaaatg
     7621 ttccttgctt gataattagt taggacatgt caagtgaaca aatgcattta cttagccaaa
     7681 aaatctaaaa acttcataaa tagacaaaaa gacacgactc tctaagaagt cgtgtcttta
     7741 ttcaacaaat tattataatt tagtcacttc agcagcttga ggtccgcgtg caccttcaac
     7801 aatcgtgaat tctacttctt gaccttcttc taggctcttg aagccgtctc cttgaattgc
     7861 tgagaaatga acaaatacgt catctccgcc gtctactgta ataaacccaa atcctttttc
     7921 attgttgaac catttaaccg ttccgtgttc cataaatgta tatcctccaa aaaagttctt
     7981 gcaagtaacc ttgcaagaac attataccca atttagaaaa cgctagcaag ctttcgctct
     8041 tttattttcc aaattatttt taagactgat atgacggagg aaatggttat tttgctgctt
     8101 cgaaacgttt gtttacttca tcccaattaa taacattcca gaatgctgca atataatctg
     8161 gtcggacatt tttatatttc aaataataag catgttccca aacgtccaaa cctagaattg
     8221 gtgtctttcc ttccatcaat ggagaatctt gatttgcagt agaggtaata gctaattttc
     8281 cattttccat tacaagccaa gcccatccag aaccaaatcg tccagcggct gcttttttga
     8341 attcttcttt aaaagaagaa aaatcaccaa aagcttcatt aatcgcttct tttatttctc
     8401 ctgtaggttc gccaccagca tttggtgcca tgatttccca gaaaaatgaa tggttagcat
     8461 gtccgccacc attgttacgt acagctgtct tgatatctgt tggaatagcg tccatatcag
     8521 ataataattc ttctattgtt ttttcgccta attctgggta tttctcaatt gctgaattta
     8581 aattcgtcac ataagtattg tgatgcttat catgatgcag atgcatcgtt tcttcgtcaa
     8641 tataaggttc caatgcgtca tatgcataag gtagatctgg taatgtgtaa gtcataaaaa
     8701 aattcctcct caatgttttc ttaataatgt ctacattaca aagagtaaca aagagaagga
     8761 aattcttcaa ttgttatgcc tagtcgtctt tttcactttg acctacttct tcttcaaaaa
     8821 cctcagtttc tttaaaaata aacaacttgc tgaaaatata gttcgcaagg ataacaataa
     8881 tttgagtgat gattttcgcc acatactcat tgctgttcat aacattgatc aacaatacca
     8941 ttgcccccat gtccaatccg taagaaagga tacggtagaa gaagaactta ccgcattcaa
     9001 taagtgcatg tgtaaaattc ggtgattttg aatggaatac ccaaagtttg ttcgttacaa
     9061 aagcaaacaa tacagaacaa aaccacgaaa tagaattgga taaggccata cttaaatcaa
     9121 aatattggcg tgcgagagca aaactaacaa aatttacaat cgtagccaaa ccaccaaaaa
     9181 agagatagac tagtatctcc caatatcctt ttgcttctaa atatcctttt aactgtcgat
     9241 actgcttcat gagccaacct accttattaa aaattcttat ttatcatact ctatatttca
     9301 ataactttca tctttattta aaaaaattaa ttttttttga tcctttgcct ttgtctctgc
     9361 ttggatcgtc acatgtgtaa taccatattt taattttaat aaagaaatta tacgaggata
     9421 tatcttttca atctcgctta gtagctgatc ttcaaaatca atatgtccgt cgaaaataat
     9481 tatcttttcg ctatactgcc aaatatggac atgatgaaca tcctttaccc catcgattgc
     9541 ttcaatttct tgttccattt tttcatagtc gatagcaggt gcactttgta tcaaaatagc
     9601 ggcagctttt ttgatcacca ttatcgcttc tatcaatata tatatcgaaa tgatcagtgt
     9661 aataactgga tcgatccagt agatatcgaa aaaacggatc aaaattgctc cgataatcac
     9721 acttaccgaa gacagtgtat cacttaacaa atgcaaataa ctagatttta tattcaaact
     9781 ttcatctgct tcttgtcgta ataataatac tgagaacaaa ttcgcgagca atccaataac
     9841 tgctactgtt agcatcaaat gactatttat cttttctggt gaagtgaacc gcttgaatgc
     9901 ttcaacggtt aaaaacaagg ataatatgat caatatgaat gagttgatga aagcactcaa
     9961 tatttctaaa cgctggtagc catacgtacg ttttttattt gcttcttttc gggccatttt
    10021 ttgtgccccg taagaaaaaa taattgccaa tgtatcacta aggttatgga aagcatctga
    10081 aacaagagac aaactccctg acataatccc tccaataaat tctgataaag tgatcaccgc
    10141 attcaaaacc actactccaa atagtttttt tgatgatctc tgtggctgtg taggcactat
    10201 tccttcctcc attttattta tattggatag tctttagaca agaataacat ttttttgata
    10261 tttcaccaat cattcagctg tttccttaaa gcacttgtat ttcacttgat acttcgctag
    10321 aattgcaagt gatgacacta ctagatgagg agtacttatg acaacaaaac aattaattat
    10381 cagttccttt atacgattca aagacctaaa ggaggcgaga aatgtcccat tttggaaagc
    10441 cattgtctat cttttagttt tgagtataat tatggctttg ccaatctctt ttcaagtttt
    10501 tcaagtctta aacaacattc aattggatgg gcaaaagatt gctactcgca ttcctgattt
    10561 tacaatccaa aacgggcagc ttcaaaccga agaaaaagaa ggattcattt accaaacaaa
    10621 ctccattatc ttcacatttg atccagaggg aaaacgaaca gaacaggaca tctctactga
    10681 tttgatgggg aattttgtta gtgtcgggat gttaaaaaac aaacttatca tagctcttcc
    10741 taatacaggc acgacttctg ctttgttgaa caataaccaa ttagaacttc cctacaccaa
    10801 tgaatcttta aaaaacttaa caggtaagca gctccgttct tttttaagtg aagcatctat
    10861 accactttgg ataaaagtcc tgacatttat attttctatt tatcctagtt ttctgaatct
    10921 gctgatcact ttgctattta ccaacattgc tgcttttctc tatgcacgct ttcgactaac
    10981 aaaagctact tttcttgatt gtttaaaaac attgatctat tcaatttcat tgcctactat
    11041 aattgcaaca atcttgatgg tctttcttcc ttcttttgac actagcgcct tcattgcttt
    11101 tgcaggaatc tttatttttg ctcaagctgt caaaggatgg gcaaaaatat cgatcaatta
    11161 agaaataaag acaactcgtt atttctactt caatagaccc ttttagaggt tgtgacattt
    11221 ttttgtcaca gccccttttt tatttgaaaa atatttcttt ctcaaaaaac aagcaaggcg
    11281 cttcaaagtt cttcttgtat gcgctacact tagagtaaag aaaggcggga aattaactat
    11341 gtcagaaaga atcatttatg cagatcgtcc atttcgtgat gaatttatcg aagaaatcca
    11401 tactatagcg cctggttata tctttaaaac agaattacaa ccagaggatc tacaaaatgt
    11461 agagatcagt ttgggctgga actcagacta ccaagaaaaa ctattagcct cttctacctt
    11521 gaaatgggtc caatctatct cagctggtgt tgatcagcta ccccttgaga ctttttcaaa
    11581 gaaacatatt ttactttcaa atggtagtgg catccacagt gaatcgatta cggagcatgt
    11641 cttaggaatc atccttgggt attctcgtgg tctttttcaa gcacaaaagg cacagagtga
    11701 catgaaatgg ttaggttcat cggtccatta ccaatctatc caagggaaaa aaatactaat
    11761 cattggaact ggccatattg gaaaaatgat tgcaaaaaaa tgcaaagcat tagacatgaa
    11821 ctgctatgga atcaatacat ccggtcatcc agcagaagga atggaaaaga ctttttcttt
    11881 aaatcaacta aaggaagttc ttcctgaagt agatttcgta gtcaatatct tacctctaac
    11941 ggaggaaaca actgggctct ttgatcagca tatgtttgaa cactttgatc caaaatctgt
    12001 attcatcaat gttggccgtg gtgcttctgt taagacacaa gatctggtgc aggctttaaa
    12061 taaccagcaa ctttcctttg cagcattaga cgtttttgag gaagagcctc ttccacaaga
    12121 tcatcctctt tggaaaatgg acaatgtact gattacttcc cacattgcag gtttgacacc
    12181 tgattttcaa aagaaattaa tggctatttt tttaaccaat ctgaaaagct actttgccac
    12241 ccatgagctt caaaccaatc aagtaaaatt gtctgcagga tattaatagc tgaaaacaat
    12301 attttcaaaa gaaaaaagag aaggtgacaa aaattgtgtc accctctctt tttttattgt
    12361 tttttaaagt gataggttgg ctcctccagg ttgggatcat aatcaacaag taaatcatat
    12421 cctttaaaga accattcatc tgcttcctcg ataaaaaaaa gtgtcccatc aatttccact
    12481 ttctttacag gatgttctgg ctgttcaact gacattccaa tcgaaaaacc atcatgaacc
    12541 tctgttttgc cgtagacttt tccaaaaaaa cgtattccgt aagtttctgg cagatcaatt
    12601 tctgagtcaa accacttttg tgcttttggc gttaccgtta atttcatccc aacaacctac
    12661 tttctctttt ctttctattg attcatctta tcgtctagaa tatccacatc gcctgtctct
    12721 ccaataacca gtagattatc attttcacga acatattcat ctgctgcagg agaagcgata
    12781 accgtttgat ctactcttcg tatggcgact actgttaagt caaaacgttg cctgaaattt
    12841 aattcagcta atgttttgtt gaaaaattta ggattggaga ctcggatttc tgctaaagaa
    12901 tatttatctg acaactctag gtaatctaaa atattctttg acactaaatt atgcgcaatc
    12961 cttattccca tgtctcgctc gggatggacg acgcgatcag ctccgatctt ttcaagtact
    13021 ctggcatgat actcattttg ggcttttgct aaaatatttg gtacgcccat ttcctttacc
    13081 atcagagtaa ctaagatact ggcttgaata tcttctccaa tagcgacaat tacatgatcg
    13141 aaatttctta tgcctaatga tcgaagtgtc atttcatcct gtgcatttgc cacaacagca
    13201 tgagtggcta tattcatata ttcattgacc cgatcttcat tactatcaat agccagtact
    13261 tcttgaccag cttcgatcag tgttcggcag atacttccgc caaatcgtcc aagacctaca
    13321 attgcaaaat tttgtttcac cgttttcctc ctttagtatc ttcttttctc agtataacaa
    13381 agcctttaca aaaacaaaag caagcatcat tattgtaaaa aagccaagaa aaataatagt
    13441 tattttctca gcttttgatt atcctcttta tcatcgtttt tatttcacca aaccatgttt
    13501 gaatgcatag atagcggctt gtgtacggtc ttccacttct agcttagcca atatattgga
    13561 aacatgtgtt tttactgttt tcagtgtaat aaacaattcg tccgctattt cctgattact
    13621 ttttccttca gaaatcagca ttaaaatttc attttcccga ttcgttagtt cttcatgtaa
    13681 tacaggctca tttcgccgac tcattttttc catcattttt gttgtcactt ctggttctaa
    13741 tactcgctcg ccacgttgcg ttgcccttat agcatcagca atttcatgtg cggtagaggt
    13801 cttcaacaaa taccctgctg cacctgcttc aatggcagga taaacttttt cgtcatcaat
    13861 aaaactggtt acgataatga ttttagcttc tggccaatct tttaagattg cttttgttga
    13921 ttcgatacca tccatttctt ccatgactaa gtccattaaa atgacgtccg gtcgaagtgt
    13981 catcgccttc tcatagcctt gtcgtccatt ttcagcttct ccaattactt caatgtcttc
    14041 ttgaatagat aaataaaaag agacgcctaa gcgcaccatt tcatggtcat ctactaataa
    14101 aacttttatc atccttatct atgcctcctt catcaaaggg accttgattt ctacacttgt
    14161 accttgacct ttaaaactaa tgatttttac tgttccacca ataccagcta ctcgttcttt
    14221 gatattgttc aatccataac ttcccgtttt cgtttcattc atattaaacc ctgttccgtc
    14281 gtcaataata cgtaacaaaa gattattgtc tattttgtgc aaatatacct ctaattcatt
    14341 ggctttagca tgtcttaatg tatttgataa caattcttga acgattcgga acaagtgatc
    14401 ctcaatggaa ctagatagtt ttacatcttc tacatcccat ttcagcgaaa tctggatttt
    14461 attttgcaat tccttcaata actgctcgat accttgcttt aaacttttct cttctaaatt
    14521 gactggacgt agatgaagaa gcagcgcacg catctcagac tgggaagcgt tgatgatctc
    14581 tgctaccatt ttcaactgct tgcgaaacat ttctggtgtc tcgctttttt ctgcttgctc
    14641 cgtcaatgcc gacatcatca tcattgctgc aaacaattgt tgcgaaactg aatcatgcag
    14701 ctcacgggct aatcgatgtc tttctaattc taaaatttct tctttggttt gtccatctac
    14761 atattgggga cggctcgtta caatttgtaa ttcactagat acttcaatca ttttttcttt
    14821 tatcttagtg atttccttat caatatcttt gatgtataaa tcgtccgatg cacttgggat
    14881 cggaagaagc aacaatttgg attcataatt gccagaagaa agtgcacgca gcttttcttc
    14941 gattttcccg tattttgtct tttgaataag tgataataat agaaagacaa ttaatcctac
    15001 acctaaggaa atggctatca aatggaagat aagcggaaca tataataaac gtgcacgcag
    15061 taattctccc caccaatgac tttgattgct ggcataaaaa taagtgaaaa gtgaaaatag
    15121 aataataagg aaagccgcaa tccccgaata aacagctagc atcgctctgg atatttttcc
    15181 catcatattc gtatcacctc gacatctcca atcaaggtat tagtaataat cttcaatcta
    15241 cgagggtttt catcataatc actgctgtag attttgattt gttcattttt caaagaaaat
    15301 tgctcttctt caaacaagac atttcctact aatgtcgcat gctctaatcg gatggctacg
    15361 cccaaaggta ctaagatccg tgttctgcct atcccttttc ttacaatcac aatattatca
    15421 tcttttggca aaagcgtatt gcccaaatct atgatagtat caccagaaat gacggcgatg
    15481 ttgatatcgt cccattcata gacgtcgttt ccaatacgtt ggttaccgaa taattgctgt
    15541 cttttccgct cattattatg tgtttttaat tgctctgttt ggatcatcat gatctgtttc
    15601 tttcgccaaa aagcattttt ggttaaatct atccctgaaa tctctacacc tttcagacca
    15661 ataaataaaa cggcaaatac agccatcatc cataaagcag gactgttgac taagctaaaa
    15721 aaaatgacca aacttcctaa tatcaattga aaattttgaa atttagtacg aggatgtttg
    15781 cgcatagcta gatatatatt gaaaataccg aatatcacta aaagcaaaag tccagtattg
    15841 tttacgattt gccaaacagc aaataacagc agtagtgctt caactaccac aaaaaaacgc
    15901 caagaactat tcatcgctct ttctccctcc tgacacattc tcatttcatc atacctattt
    15961 ttttaactgt tggctatagg actttagatg taagatcgtt tgttgaaatc taaaatacac
    16021 aaagagaaaa agatctagag tgtatcatca gtaagatgaa ctctctagat ctttcagtca
    16081 gactacgctt gttctacttt gacgatttta actaacatat cgccacctgg agtagcaata
    16141 gttacttcat catttttacg tttgccaatc aatgcttgcg caataggaga atcattggaa
    16201 attttgccag aaaacggatc tgcttcagcg cttccgacaa tcgtgtactc ttcttcttct
    16261 ccatctggta gttcgatgaa tgtaactgtt ttaccaattg atacctcatc tgcatctaca
    16321 ccgtcgttat cgatgatttg agcaaaacga atcatatttt caattgttgt gattcttcct
    16381 tcaacaaatg cttgttcatc tttcgctgat tcatattcag agttttcgga aagatctccg
    16441 aaaccgcggg caattttgat tcgttcaatg atttctccgc gtttgactgt ttttagttct
    16501 tctaattctt tttctaattt ttctttacct tctagagtca ttggataaac tttctctacc
    16561 atgtgtaacg tctccttttt tcgataaaat accgcaaaag gtaatctttt gaggaatata
    16621 gtccaaaaaa gattaccacg cttttcttca aatgtaaatg tttttctaaa aatgatcaat
    16681 gtctagagcc tgtttttcta agaattattt acatattttt ccactaattc catatgttct
    16741 tcataagttt tagcgaaata aacatttcca gtgctcgtat ctgctacgaa ataataatag
    16801 tcattttctg ctggttctaa tactgccttg attgcctctt cgcttggatt gtcaaaaggt
    16861 ccaggtccat agccggtatt ggtatacaaa ttatatggtg aatctacagc tgtatcttca
    16921 tacgtcacta attctttgtg ttcacctaat gcgtataaaa cagagatatc tgactgaagt
    16981 ggcatatttg ctttgattcg gttaaagaag acttgtgcaa tgtttttacg atcattttct
    17041 tttacgcctt ctttttcaac tagagaagct agagttaaaa cttcttgtac agtcaaattt
    17101 ttctgcttga tagctgaata atagttttgc atgaccgtat tcgtcttgtt caccatttca
    17161 atcactagat ccttaagcga agtactcgtg taataatcat atgtggctgg gaataagtaa
    17221 ccttccaaac ggtattttgt gttctcagct ttagatgcac tttccaacag ttctgggaat
    17281 ttttggtgca actcgttaaa gaaagtctca tcattcacta aatctaaaaa ttctttcttg
    17341 tctttaccag ttaccttcgc tacccgttca gcaatctgat cgatatcgta cccttctgga
    17401 atggcaattt tcccatctgc aacttttgtt ggctcagaag taccgccttc ttgcaactgt
    17461 ttgccaatct cgtcaagagt catattaggc gctaactgat aatagccagc ttgaaagcca
    17521 gttaaatttt taaattttgt ataataattg aaaacaatcc cgcttttaat aatattgtcc
    17581 ttctccaaaa tctcaccaat ctgcttgtta gaagagccac tcgggatctc gacttggact
    17641 aattggtcat ctgatttatc taaaggcttc aacccgctat ctacataacg atacacggta
    17701 aatccaagaa atccgccaat aatcaataat gtaagagcaa tcactaaaat gatcttcctc
    17761 acaatcttat cttctttttt acgcagattt ctccgcttgt cgattatatc tgctgtagct
    17821 gccttactgg cttctttttt atctttactt gggtgttgtt tgtttcctga caaaacaact
    17881 cctccttact atcaagttcg taactttatt cattatacat gatatttgaa ttggcgtgaa
    17941 tgattttatt taaatattct atcaaaaatg taagtagtaa atccattact ataagattaa
    18001 aataaatgtt atcaagatac aagctatttt agctttattc tttctgtaaa aaagaaagga
    18061 gactaaataa actattatga aaaaaggaaa acatgctaaa aaaagaaaat attcattttt
    18121 aatgatcgtt gtcgtgttgt ttagccttag tgcgttctct acaggaacta ttcttggatg
    18181 gcaattttac aataatgaac actctcagat agttgcccat gctcaatcag ctcaaaaaaa
    18241 gttgatactg actaccaatg aacaacagct cgttgaaaaa atcgatcaac tattaagaaa
    18301 aaatgattat attggctcaa tttacgtaaa gaaaaataat cgcatcatca tggaaaaagg
    18361 ctatggctat gcgaataaac tcacgcaaca accaaatgat ccttctcttt attatcagat
    18421 tggttcggtt caaaaagcat tgactactct tttgatttta aaacaagtcg agcgtgggca
    18481 cctttcttta gatactaagc tggctcaatt ctatccacaa attgctggca gccagcaaat
    18541 tactatccgt gacttgctgt atatgcgctc aggcttgcac cgaactgctt ctccaaccat
    18601 accgatgact gatgaagaag tcgttcaatt tgcgattcag cacttaaaat ttacagatta
    18661 tcagacctct cattatgatt cattgaactt taccatattg actggaattt tgatcaaatt
    18721 aacaaatcaa ccgtatgaaa aattattgac cgatgatatc atcgaacctt taggattaca
    18781 gcatacaaaa ttttatgacc aagtcaaaaa ttcatccaat catgcactat cctatcaaat
    18841 gtctaaagag gatgattact ttaaaccact gacagaatct gaaacagaga tccataacga
    18901 attagggact ggtaatatca gtatgtccgt ctatgattta aatacgctgt ttacacaagt
    18961 tttatctgga aaactagttt ccaaagactt actcttctca ttatggcgtg aaaatgcgaa
    19021 tggacatcca tatagtggtg gggtatatag cggagataat tatatcctgt cgcaaggaaa
    19081 tatcgactct tttgatacat ctgctatatt tagcaaagat tcacaggatg ctatcatcat
    19141 ggaaagcaat ataaaagctg acaaaactat caaactgcct actgctgatc taagaaacca
    19201 aatctatgac ctgatggaag gaactactaa gttggcaaat agctgatatg atgaaaagat
    19261 agcaaatact acttctttga atagcatttg cttaaaaaaa gtactcgact aaacgtagga
    19321 aagagtgtgg gacaaatcta aaaatcaatt tttgctacag actttaattc caaataaaca
    19381 gaacagaaag aggtgttctt ctttctgttc tgtccaaatt attctaagat ttctctttac
    19441 caacattatt tgacaaaggg cctattaaat ctaaaatagt atctttagat tgctaaaata
    19501 tgtgctagca aatcattcat ggcttgttct tatttttaat tttatgcaat aaaaaagaag
    19561 aacaattagc gtgattatag aaataaataa tgagatttta gaaaaaaatg tgtatgaata
    19621 cctgattgtt actttattta ttccactttc actttttact gtaacaaaag gacctccttg
    19681 ttttagtact gtagcatttt ttgaattaac agtaaccgtt aatcctttat accggaatac
    19741 aggtaaaact attgttttgc cttttgaaga tttaaacgta aatgtaattt catctttatt
    19801 tggagaaaag ctactataaa taacttgacc atcttctgta acttgatggt ttttcaaaag
    19861 caattgatct tttttatagc ctataggtac ataatcaaaa ttctcaaatt cttcaagttt
    19921 attttccatt tgttcattag aataagttcc ttgaaaattc atttctttca ccatgttaac
    19981 tactgatgaa taatttaaaa ttgaaatagc taatattaat aatagtataa aatttcttct
    20041 ccttgtataa gaaaattttt ccaactgtgg agaaataaat agagatactg aaaaagatat
    20101 gaacaatgtt gaaaatatca taaaacgcca aggagcttga ataatattta aaggagtatt
    20161 ttgtaaggca aaccatggaa atatttttgt acaaagtaga atagatatta tacccattat
    20221 ataagtgatt ttagataaga ttcctaattt tttaaagtta aatgttagta taattaaaca
    20281 aataagcaaa gttaagccaa taccaaatga tagtaattct gaatctatac ttccaatcaa
    20341 aaactcttta cccagataaa ttgctctttt ttgtaatata tccacataag gtctattcag
    20401 atcttgatac aatgtctgct caatcatagg acctataaac gctagtgaaa gaagtaaagt
    20461 aactatagca gcttttatta atttaataat taagaagatt tctattttct ttttccgata
    20521 aaattgaata attaaagcaa ttataatcat taccatagtc atagctacag aaagaacatg
    20581 agtgtaaatt aataaagtca tgctaatcgc caacataacc caagattctt tttttgagtc
    20641 gtaaagcttt ataaacccga gtaaaataag aggaagtatt gacattgcga gtaattcccc
    20701 cattgcccct cgaagaaata tttctacact cctaaaagaa gatgttgtat atataatagc
    20761 gaaaaaggag ctagtaacat gttttttggt aatttcatac attacataat gacatataaa
    20821 tagagtaatg agcgtaacaa tataaagaaa aaggttatag cctattgcta aattagtaaa
    20881 cttgatcaat aaaaataaag gatatagagt taaccatggg taaaaattat ttacttgcat
    20941 gccatatgat ctaaacgttt caaaattaat aggggagcta aaaatagatt ctaaacttaa
    21001 cgcacgatta atgtgaaatg ccgtatcata aaagccaaat atttccatgt ttttaaatgc
    21061 tggaaataaa tataataaac taacaaatgc ataaactata aatattttta cagaaaaaat
    21121 ttttttcaaa ttcatatacc acctcatgtt tttttatatt acatatagta tcatttattt
    21181 tttttaaaca ctagattagt cactatataa aatgtgatta attttattat taataaaata
    21241 ttttttatat tacaaaagta gtgttt
//
LOCUS       DASHXG010000044        21198 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.044, whole genome shotgun sequence.
ACCESSION   DASHXG010000044 DASHXG010000000
VERSION     DASHXG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.044"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            2..77
                     /locus_tag="U2R59_001945"
     tRNA            2..77
                     /locus_tag="U2R59_001945"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            79..149
                     /locus_tag="U2R59_001946"
     tRNA            79..149
                     /locus_tag="U2R59_001946"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Gly,seq:tcc)
     gene            163..236
                     /locus_tag="U2R59_001947"
     tRNA            163..236
                     /locus_tag="U2R59_001947"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:197..199,aa:Ile,seq:gat)
     gene            261..348
                     /locus_tag="U2R59_001948"
     tRNA            261..348
                     /locus_tag="U2R59_001948"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Ser,seq:gct)
     gene            370..441
                     /locus_tag="U2R59_001949"
     tRNA            370..441
                     /locus_tag="U2R59_001949"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Glu,seq:ttc)
     gene            464..553
                     /locus_tag="U2R59_001950"
     tRNA            464..553
                     /locus_tag="U2R59_001950"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:500..502,aa:Ser,seq:tga)
     gene            566..639
                     /locus_tag="U2R59_001951"
     tRNA            566..639
                     /locus_tag="U2R59_001951"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Met,seq:cat)
     gene            658..730
                     /locus_tag="U2R59_001952"
     tRNA            658..730
                     /locus_tag="U2R59_001952"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:Asp,seq:gtc)
     gene            734..806
                     /locus_tag="U2R59_001953"
     tRNA            734..806
                     /locus_tag="U2R59_001953"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:767..769,aa:Phe,seq:gaa)
     gene            811..881
                     /locus_tag="U2R59_001954"
     tRNA            811..881
                     /locus_tag="U2R59_001954"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            894..967
                     /locus_tag="U2R59_001955"
     tRNA            894..967
                     /locus_tag="U2R59_001955"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:928..930,aa:Ile,seq:gat)
     gene            979..1050
                     /locus_tag="U2R59_001956"
     tRNA            979..1050
                     /locus_tag="U2R59_001956"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1012..1014,aa:Glu,seq:ttc)
     regulatory      1239..1318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1316..2509
                     /locus_tag="U2R59_001957"
     CDS             1316..2509
                     /locus_tag="U2R59_001957"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEM8966329.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            2639..4111
                     /locus_tag="U2R59_001958"
     CDS             2639..4111
                     /locus_tag="U2R59_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8966330.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4194..4982
                     /locus_tag="U2R59_001959"
     CDS             4194..4982
                     /locus_tag="U2R59_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEM8966331.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5049..5717)
                     /locus_tag="U2R59_001960"
     CDS             complement(5049..5717)
                     /locus_tag="U2R59_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEM8966332.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5832..7544
                     /locus_tag="U2R59_001961"
     CDS             5832..7544
                     /locus_tag="U2R59_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966333.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            7547..9319
                     /locus_tag="U2R59_001962"
     CDS             7547..9319
                     /locus_tag="U2R59_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966334.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(9401..10522)
                     /locus_tag="U2R59_001963"
     CDS             complement(9401..10522)
                     /locus_tag="U2R59_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8966335.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(10594..11874)
                     /locus_tag="U2R59_001964"
     CDS             complement(10594..11874)
                     /locus_tag="U2R59_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEM8966336.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(11965..12417)
                     /locus_tag="U2R59_001965"
     CDS             complement(11965..12417)
                     /locus_tag="U2R59_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEM8966337.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(12430..12840)
                     /locus_tag="U2R59_001966"
     CDS             complement(12430..12840)
                     /locus_tag="U2R59_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966338.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            13115..13327
                     /locus_tag="U2R59_001967"
     CDS             13115..13327
                     /locus_tag="U2R59_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966339.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            13330..13542
                     /locus_tag="U2R59_001968"
     CDS             13330..13542
                     /locus_tag="U2R59_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966340.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            13682..13837
                     /locus_tag="U2R59_001969"
     CDS             13682..13837
                     /locus_tag="U2R59_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966341.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(13834..14058)
                     /locus_tag="U2R59_001970"
     CDS             complement(13834..14058)
                     /locus_tag="U2R59_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HEM8966342.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            14136..14324
                     /locus_tag="U2R59_001971"
     CDS             14136..14324
                     /locus_tag="U2R59_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966343.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            14321..14494
                     /locus_tag="U2R59_001972"
     CDS             14321..14494
                     /locus_tag="U2R59_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966344.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            14650..14985
                     /locus_tag="U2R59_001973"
     CDS             14650..14985
                     /locus_tag="U2R59_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966345.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            15218..16159
                     /locus_tag="U2R59_001974"
     CDS             15218..16159
                     /locus_tag="U2R59_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HEM8966346.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            16161..17051
                     /locus_tag="U2R59_001975"
     CDS             16161..17051
                     /locus_tag="U2R59_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEM8966347.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            17094..17894
                     /locus_tag="U2R59_001976"
     CDS             17094..17894
                     /locus_tag="U2R59_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEM8966348.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            17909..18760
                     /locus_tag="U2R59_001977"
     CDS             17909..18760
                     /locus_tag="U2R59_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8966349.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            18961..19422
                     /locus_tag="U2R59_001978"
     CDS             18961..19422
                     /locus_tag="U2R59_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8966350.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            19448..19900
                     /locus_tag="U2R59_001979"
     CDS             19448..19900
                     /locus_tag="U2R59_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966351.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            20006..20200
                     /locus_tag="U2R59_001980"
     CDS             20006..20200
                     /locus_tag="U2R59_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966352.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            20231..20524
                     /locus_tag="U2R59_001981"
     CDS             20231..20524
                     /locus_tag="U2R59_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966353.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            20554..20994
                     /locus_tag="U2R59_001982"
     CDS             20554..20994
                     /locus_tag="U2R59_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8966354.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            21069..>21198
                     /locus_tag="U2R59_001983"
     CDS             21069..>21198
                     /locus_tag="U2R59_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEM8966355.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQH"
BASE COUNT         6826 a         3466 c         4361 g         6545 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgccatgc gggtgtagtt tagtggtaaa accacagcct tccaagctgt
      121 tgtcgcgagt tcgattctcg tcacccgctt ttagtttttt atgggcctat agctcagctg
      181 gttagagcgc acgcctgata agcgtgaggt cgatggttcg agtccattta ggcccattag
      241 tacaaaatct tattggtttt ggggaagtac tcaagtggct gaagaggcgc ccctgctaag
      301 ggtgtaggtc gggaaaccgg cgcgagggtt caaatccctc cttctccgtt tcaatatttt
      361 gttttacctg gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg
      421 gttcgaatcc cgtacgggtc attaatttaa tatagtttta catggaggat tacccaagtc
      481 cggctgaagg gaacggtctt gaaaaccgtc aggcgggtaa aaccgtgcaa gggttcgaat
      541 cccttatcct cctttttcat attatcgcgg gatggagcag tctggtagct cgtcgggctc
      601 ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat taaaaactaa aaacattggt
      661 tccgtggtgt aggggttaac atgcctgcct gtcacgcagg agatcgcggg ttcgattccc
      721 gtcggaaccg tttggctcgg tagctcagtt ggtagagcaa tggattgaag ctccatgtgt
      781 cggcagttcg attctgtccc gcgccattat gcgggtgtag tttagtggta aaaccacagc
      841 cttccaagct gttgtcgcga gttcgattct cgtcacccgc ttttagtttt tatgggccta
      901 tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcgatggttc gagtccattt
      961 aggcccattt attttattgg cccgttggtc aagcggttaa gacaccgccc tttcacggcg
     1021 gtaacacggg ttcgaatccc gtacgggtca tggaagatac tttttgagta tctttttctt
     1081 tttatctgaa agaatgattt taaaaagctt agcagagtta tctttatgga tgattgtgct
     1141 aagctttttt ggacagttct aatgtaaaat atttttatat tttttaagca aaaaaatgaa
     1201 aaaatacgag cagaaaactg ttttatctgc tatacttggt tcgttgcaag ttcccgaaag
     1261 gatccgcagg acggagatgc cttgtaaccg aatttaacta gggggaatca ttataatggt
     1321 agaaagacac ttatttacat cagaatctgt ttctgaagga catccagata aaattgctga
     1381 ccaaatcagt gatgcaatct tggatgcaat tttaaaacaa gatccaacag cacgagtagc
     1441 gtgtgaaacg tctgtaacaa ctggtcttgt tttagtattt ggagaaatat ctacgacggc
     1501 atatgtagat attcaaaaag tcgtacggga aacaataaaa gaaattggtt atacacgtgc
     1561 aaaattcgga tttgatggag atacagcagc tgtattggtt gcgattgatg aacaatctcc
     1621 tgatattgct caaggagttg atgaagcact tgagatccgg gatgaagata aaaaagacgt
     1681 attagatgag attggtgctg gtgaccaagg tttaatgttt gggtttgctg tagatgaaac
     1741 accagaattg atgcctttac caatcgcttt gagtcatcgt ctggtacgac gcttggcaga
     1801 tttgcgtaaa tcaaatgaat taacgtattt acgtccagat gcaaaatctc aagtaacggt
     1861 tgaatatgat gatcaaggac aaccggaacg cgtagataca atcgttattt caacacagca
     1921 tgatgatgca gtagataatg aaacaattcg tcatgatgtc atcgaaaaag tagtgaagga
     1981 agttattcca gctgaattat tagatgatca aacgaaatat tatatcaatc cgactggccg
     2041 atttgtcatt ggtggtcctc aaggggatgc cggattaaca ggaagaaaaa tcattgttga
     2101 tacgtatggc ggttatgctc gtcatggtgg cggtgctttt tctggtaaag atgcgacaaa
     2161 agttgaccgt tctgccagct atgctgcacg ttatattgct aaaaacattg ttgcagcagg
     2221 gcttgctcgc aaagcagaag tacagctagc ttatgcgatt ggtgttgctc aacctgtttc
     2281 gatctcaatc aatactttcg gtactggaac ggttccggaa gaagaactga ttgctgcagt
     2341 gagagaaaac ttcgatcttc ggccagcagg aatcatcgag atgcttgatt tgcgtcgtcc
     2401 gatttacaaa caaacagctg cttacggtca ttttggtcgt acagatgtag atttgccttg
     2461 ggaacatacg gacaaagtag atgcgttgaa agcaagttta gcaaaataag ttatattcag
     2521 ctggaacgat cgccaagtgg tggttgttcc agcttttttt atggcagtta acctcttgaa
     2581 aaagatagta attatttatc tatttttaga tcctgtcata atgaaaggga ggaataagat
     2641 gaaaaaagaa acaaatgtta ctttggtcac agtgagtatt ttcattgcaa cgttcatgac
     2701 ggctattgaa ggtacaatcg taacaaccgc tatgccaacg attgtcggtt cattacatgg
     2761 aatggaaatc atgaactggg tattttcgat ttatttgctg acaaacgcta tgcttactcc
     2821 gatttacgga aaacttgcgg ataaagtggg acggaaacca atctttattt ttgggacatt
     2881 attgtttatt atcggttcgt tattttgcgg tttatctcaa agcatgattg ggttgattgc
     2941 tgctcgtgcg attcaaggga tgggtgctgg ggcaatgatg ccagtagctt tgacgatcat
     3001 cggcgatctt tattctattg aaaagcgagc aaaagtttta ggtttgaata gttcagcctg
     3061 ggggattgcc agtgtttttg gaccgcttgc gggaggattc atcgttgaaa cgatcagctg
     3121 gcactggatc ttttttatca atgtgccgat cggaattcta ttaattattt tgatttggct
     3181 atatttaaat gaaccaaaaa tcatacatga gtctaaacca atggatattt ttggtagttt
     3241 tagtttgatg gccatgcttg tctcattgct gttagggttc caattattag gagacgaagg
     3301 aatgagtccg cttgtttctg ctttgctgct aggtagtatc gtaatgttag gtatttttgt
     3361 ttttgccgaa aaaagagcta aagatcctgt catcatgatg catttattca aaaatccact
     3421 atttgttgtg gtcaacttgg ctgcagcatt ggctagtggt tttttgatgg gaatcgatgt
     3481 ttatatccct atgtggatgc aaggtgtatt agggctgaat gcagcaattg gtgggctggt
     3541 attagcacca ttatcactag tctggatggt cggttctttc cttgcaagca agtggatgac
     3601 tcaaatgaaa actcattggg tcttgagaat tggactacta atcgcagcta ttgggggcgc
     3661 ttggttgtat cttatgcctt tcagaagtaa ctatttatgg ttttttgcta tatcaacggt
     3721 catcggtata ggcttaggtg tgaccatgac tacctcgact gtcagtgcac aaaatagtgt
     3781 atctcgtgac cagcttggtg tagcaacttc ttttaatacg ttagttcgaa caattggtca
     3841 aacagtcatg gtttctattt ttggtttatt gataaatggg gtaactaaac gagaacttgc
     3901 agcagcaaat ttaacaaatg atgcagatat catgaataaa ctggtgaatc cacaaacggc
     3961 taaatatatt gatgcggata ttttgttacc attaagaaaa attctttatg atgggttaca
     4021 ttccgtttat ctagttggct tgttactcgt gatcattgct ttggtcttaa cgcttttcgt
     4081 tcatgaaaaa agtggtaaaa taaaacagta gtttcggtta agatatgtac gtagccgaat
     4141 cattcaaatt taaagttatt caaaaataac ttcttactaa ggaaggcgaa aatatggcat
     4201 ttattcaagc aaatatttat tcgaatgtgt tagaaatgga agtcaatcta aatgtgatac
     4261 taccgcaaac aacaaaaaag gtgattggca ccagttcaga gcaagagaca acggatatac
     4321 ctgttttata tttacttcat ggaatgggtg gcaatcatag tgtatgggaa agacgtacgt
     4381 cgattgaacg ttatgtagca aactacggat tagctgtcat catgccatct actgatcttg
     4441 gctggtacac agatacagtt tatgacatga agtattggac attcattgca gaagagctac
     4501 ctgagatttg tcatgaatta ttcccgcaat taacaagaaa aagagaaaaa acatatgccg
     4561 ctggattatc gatgggcgga tatggcgcgt taaaactagg ccttgcaaaa tcagaaaatt
     4621 tcgcagcagt aatctctctt tcaggcgctg tttctgtagg aaatcgaatg gatgatcttt
     4681 tgatggttcg taaagcatct ttttgggaag ggatctttgg accattggat caaatcgaag
     4741 gttcaaaaaa tgatccgcaa tacttattga aagaactagt aaaaagcgga aaaccagttc
     4801 caagatttta tatggcttgt ggggaatctg attttcttta tcaggcaaat caggaaatgg
     4861 tatctgctat gcaggaacaa ggcttggcgg tcacctttga acaaggacct ggcgatcata
     4921 actggatctt ctgggaccaa tggattcaac gtgcattggc gtggctaatg gaagaaaaat
     4981 aaaaaaagag tcttaaaaag atagctccta tagagatcac aaacatagtg atctctatag
     5041 gagctttttt actgctcgtt ttctcttctt ttattttgtt ggcataagcc ttcaatatag
     5101 gtttgtgcac tcgttagaaa gagtgctttt tcattcaatt ctgcatggga ctgcatactt
     5161 tctttaaatc cctctaattg attttcaact acataattac gcataaatag aactgtttct
     5221 ttcaaaaatt catttccgtc cataattttt tgtcgaagct gctgttcatg ctgctgatcc
     5281 attaactgtc caatcaataa attgtggaga gaggcaatgg cctgatgact ttgggtgact
     5341 gaaaatcctt cacgaacaag taattggatc atttgctcca aatgttctaa tcgactcgga
     5401 aaagcgggca cagtattgat ttctaattct gccccacaag ggaaacgtgt ataaaggtca
     5461 tagtaatttt ccatatactg cagcaactgt tcattccaag gcaaagttgg atctggaagc
     5521 gctaattctt cttccattgt ttcagccatt ttttgcaaga gctgttgttt gtttttgaaa
     5581 taccaatata aagcaggtgc ttgaacatga attctgtttg cgatgtttcg catggaaagc
     5641 tgcgaaagag cttgtgtttc agccaggata tcaaaggcgg cctgaatgat gattgcttga
     5701 gaaagcttta tttccatttt atcaacctcg tgtattgcat tatcttttta aacatggtaa
     5761 attgttagtc ggtctaattt tacagtgtta aattagtcct gtcaatttaa acaaaggggt
     5821 gtaatcaacg aatgaaatta atcttacgac atgcgaaaaa atataaagta tctgttttta
     5881 tttccttgct gtccgtagca gtcatggttg cagcagcatt atggcaacct aagttactac
     5941 agcaagtatt ggaagctatt attacagaag ataatgatga aatgaaaaca attggtattt
     6001 acctgatcag tctggctttg ctaggattag ccgcaggtgt aacgaacacg attttctctg
     6061 caaaagtagc tcaaggcgta agtgcagata tccgagaaga agcatttcga aagatccaga
     6121 cattttcatt tggaaatatc gaacagttct ctgctggaaa tcttgttgtt cgtctaacaa
     6181 atgatatcac gcaaatccaa aatttagtga tgatttcttt gcaatcactt tttcgaattc
     6241 cattcttatt tattggtgcc ttcattttag ctatgatcac gatgccgcaa ttatggtgga
     6301 tcatcgtagc gcttatcgtt acggtatttc tgattacggc actttcattt acaaggatgg
     6361 gcaagcactt catgatcatt caaaaactga ttgatcgtgt gaatagcatt gcaaaagaaa
     6421 acttactagg gattcgtgta gtgaaatctt ttgtacaaga agaaaaccaa ttgaagtcat
     6481 tcagcaaagt aagtgaggac ttaacaaaac acaacatcat agtcggtaca ttattttctg
     6541 tgatgatccc gtccttcatg ctggctgcca atttggctgt ggttggggcg atcttttttg
     6601 tgagcgatct tgttaaagat gatcctacgt taattggtgg aattgcttca ttcatgaact
     6661 acttgatgca gattatgatg gcaatcatta ttggcggaat gatgatgatg atgacttcaa
     6721 gagcagccgt atcgctgaag cggattgcgg aaattttaga tgctgaacca gatcttactt
     6781 atttagacgt tccagaacaa gagttgacgg gttctgtcac ttttgaccat gtttcttttc
     6841 gttatcctgg tgaggataca gatacgctta aagatatcag cttttctatc aaacctggag
     6901 aaatggttgg tatcgtcggg gcgactggtg ccgggaagtc aacactagca caattgatcc
     6961 ctcgtctatt tgatccgaca gaaggcaaag ttgaagtagg tggtgtagat cttcgtcaag
     7021 taaatgaaaa gagtttaaga caaacggttt cctttgtttt gcaaaaagca attttattct
     7081 caggaacgat tgctcaaaac ttgcgccaag ggaaaaagaa tgcaacagaa aaagagatgg
     7141 aacatgcttc ttctattgct caagcaaaag aattcatcga aaagttatct gatcgttacg
     7201 aagcaccaat agaagaacgt agcagtaact tttctggtgg tcaaaagcaa cgtttatcca
     7261 ttactcgtgg cgttatcggt aatccaaaga tcttgatcct agatgacagt acgagtgcac
     7321 tggatgctcg ctctgaaaag ctggtccgag aagcactcga tcgagatttg aagggaacaa
     7381 cgacgattgt catcgcacaa aaaattgctt ctgttgtcaa agcagaccgc atcttagtat
     7441 tggatgaagg cagattagtc ggcgaaggaa cccatgagga attggtagct ggaaaccgtg
     7501 tctatcagga aatctttgaa actcaaaaag gaacggagga gtaagtatga ctgatctaat
     7561 aaaagcaagt aaatttttct atcactattt gaagcggtac aaactctcct ttttctttat
     7621 ctttatcaca gtgatcattg ctacctatct acaagtaaag gcacctcaat acatcgggga
     7681 agcttttcaa gaattagcta attacgtagg aggcttgatg caaggcgtag acgataaaag
     7741 caaatttgtt tctgtaatat ggaaactctt gctgttttat gtactagcta gtgcagccaa
     7801 ctttatctat agtattttgt tcacacaagt agtagggaag tcaacgaacc gaatgcgtat
     7861 cggtctattc aacaaattgg aaaaattgac gatccgtttc tttgattctc atcaagacgg
     7921 tgaaatttta agtcgtttta ccagtgactt agataatatt caaaatagtt tgaaccaagc
     7981 tttgcttcaa gtcatcacga atgctgtttt acttgtcggg atcttgatca tgatgttccg
     8041 ccaaaatgta gagttagctt gggctacaat tgcttccact ccagtagccg ttttgatagc
     8101 tgtcttgatt atccgcaaag cacggaaata tgtggatctt cagcaagatg aagtggggaa
     8161 actaaatggt tatatggatg aaaaaatcag cggacaacgt gtcatcatca caaatggctt
     8221 acaagaagaa acgattgaag gattcttaga gcataatcaa agtgttcgcg aagcaacctt
     8281 caaaggacaa gcttattctg gtctactatt tccgatgatg caaggaatgt cactggtcaa
     8341 tacagcgata gttatctttt tcggcggctg gttagcatta aatggtgatt tggaacgttc
     8401 ggtggcatta ggcttagttg tgacattcgt ccagtattca caacaatatt accaaccact
     8461 gatgcagatt tcatctggat acagcatgat ccaattagcg attacagggg caagacgatt
     8521 gaatgaaata tttgatgaaa aagatgaagt caaaccagaa aacggtaaag catttgatgg
     8581 tgttgaaaaa ggtcttgcgt tgcagcacgt agattttggt tattctccag aaaaactagt
     8641 cttgaaagat gtctcgatca atgtggacaa aggagaaatg gttgctcttg ttggtccaac
     8701 aggatcgggg aaaacgacga tcatgaatct gctaaaccgt ttttacgatg tcaatgatgg
     8761 ttcagtagtc atcgatggaa tagatatccg agattatgat cttgatgcat tacgtagaca
     8821 tgtaggaatc gttttgcaag aatctgtatt gttctccgga acgatcaaag acaatatcac
     8881 attcggcaaa ccggacgctt cagatgaaga agtcatcaat gcagcaaaac aagcgaatat
     8941 tcatgacttc atcatgacgt tagaaaaagg ttatgataca gagatatccg aagaaaataa
     9001 cttattcagt acaggtcaaa agcagttgat cagtattgct cgaacgatca tcacaaatcc
     9061 atctttattg attttggatg aagcaacaag taatgtagac acggtaacag aagcaaggat
     9121 ccaaaaagca atggatgaag caatcaaagg aagaaccagc tttgtgattg ctcaccggct
     9181 gaaaacaatc ttgaatgcag atagaatcgt tgtcttgcgt gatggggaag tcattgaaga
     9241 aggcagtcat catgagttat tagcagaaaa tggattttat gcggaacttt atcataatca
     9301 atttgtattt gaaagttaaa ttaaaagaac ctcgttataa cggggttctt tttatatatt
     9361 ttatgttgtt tgtttttata aggggcagaa aaggggcaat ttaaatttct atttttccta
     9421 gtttttctac tagttgattt tgcatatttt tagttgtatg agtataaatc tttaatgttg
     9481 tttttgaatc ttcatgtcct acacgatcca taatggcttt taatgggatt cctaattctg
     9541 taagtagaga aatgtgggaa tgccttaaca tgtgagaaga aactttttta tctaggttta
     9601 attctttgga tactgctctt aaagattgat tatatgcttg aatagatatc gggttaccat
     9661 ttttagagat gaaaatgtat ttatctttat tattcttaat taatttgttt tcttcaatta
     9721 attgatctat gatttcttta gcattacttg ataattcaat ggttctataa gaacctgtat
     9781 ttttagttgt tgttttaatt tttaactcgt aatcataagt accagaaacc gtaattttat
     9841 taccatcata atcagattca gtcaaagata tcaattcacc ataacgtagt ccagttaaaa
     9901 acaaaaattt agtaattaaa gaataacgtg actgttgatg tgaacttttt tgtttactag
     9961 caatcatttg aacttcttct tttgataaat aaccatcttt ttcttttttt atttcttcgt
    10021 ttgtcttagg ttttcttgct aaagaaaccc catttacggg attatatttt aatccatatc
    10081 gacggttggc gaatttaaaa atcattcctg taaaagtttt taaatgtatt acataattat
    10141 atgataaatt tttttcaaaa tagtagtaat ctagcatatc ttgtataaga ttactattaa
    10201 cgttttttac aagtacatca tcttttatat attttgaaat taatgataga taaacctgag
    10261 ttgttcgata ggaactttct tttacagttg gcttgtattt ttcatcccat ttagttttta
    10321 attctccaaa agttagtggt aattcttcat ttcgttttat tttttctgcg attttttcat
    10381 tcaaaagtaa gttagcttga ttccaagctt ggcgtgaatt gctagataaa gtaacggaca
    10441 cttttctctt tttttcagtt aagggatccg tataacgttc ggtgtactta aattttttgt
    10501 catttatttt ttctaaccac attatttcta ttcctttcga atatacgttc ctattaattg
    10561 ttaaaagaaa aagcccgaag gctttttata tatttaatct tttgacaatt ctaaagatcg
    10621 tctatattgt tcagctttag ctaattttgt aaatgttact gttccattat aattttctaa
    10681 aacaactttc tctatttcgt ctagtgaaac tttgaaaaat tcttttcttt gattaatttt
    10741 attaacttct tgttttctaa aatgattatg caatttagtt tccaaagacg gagcgtcctc
    10801 tgaaaaaatc atcgcatgaa cgtcaaattc aaatggaacc gatgcactac tcaattcttt
    10861 tattctatcc ataggttcta atcttctagt cataccaatt ttatatatgt cttcaccaaa
    10921 agacccaata ttactaatta catacacata accggctcta gtatttaatt ctctttgtaa
    10981 tacattttca cgtataactt ctaattcttt taatttttct tccagttctt gaattttatt
    11041 tgcatataat tctttttcca catctgcatt agctttttgc atatatgcga ttaatttgga
    11101 aatttcagaa ttgaattgac gttgttcttt atcaatacgt ttcttttcac gatcaatttc
    11161 tctacgaact ttttcctctt ctatcatctg ttcttttatt gctttttgtt gttctttttc
    11221 ttcggtaatt ttcactaaat aagagtaatg aagttctagt tcttgaagtt taaactctaa
    11281 aagacccttc cttaattcag cattgtcatt cttgaataaa ttattaattt tatcaaatat
    11341 ttttatgatt ttttccctag tcgagtctat attagaaata gttagtttat tgagtaatcc
    11401 tttcacttct gaatcaaatg gaatgagcat ttttttcttt aaattatttt tctctcgttt
    11461 atttaaaata agagggacag aaacagcatc gtcaataata tattcctttt cttttaattt
    11521 taacaaagaa agcttatttt ttatttcaga agatgaagtt tcttctatat ttgaaacgat
    11581 aagtgaagaa tagacatttt ttaatgtttc atcatacttt tgatttattt catcatttaa
    11641 atcttctttc tcttttttta ataaaataat atcatttttt aacatagtaa tttgtttatt
    11701 taaatctgat agtgtttctt ccttacttaa tataaatctt tctctatcat gtaatttatt
    11761 tagtttttca tcattttttt gttctaattc ataagcttct ttttttattg tgttagcttt
    11821 cgacagttta gtgattccta taattaataa aataagtcca atcaataata acattcaaaa
    11881 ctcctcattt ctttgatata attattgtag agtttactca gaaatgagga aagagtccat
    11941 gtgaaagcat gggctttttt atttttaatg ttgtaatact aaatgttcaa gattatgagg
    12001 aagccctaaa tattcaataa tttggaactg actcatatca gataaatctt gttcatctat
    12061 tgttctagtt aacatttcaa ttgcaaacat attagcttca gcttctatac cataaatcat
    12121 acaactaagg ttgtttgctc taaaagctgc tgtgcaaata cctttatgga gtctaacgtg
    12181 ggctatttca tgccataata caaatctttt catagaaggt gataggtttt gattaattaa
    12241 tatcacataa catcttttat tgtgtatcgt ttgtcctaat gttttattcc ctaaatcagt
    12301 ttcaattaaa tctatatcag aatatttgat tattttatat ggattaatcg catcagatcc
    12361 aaactctaca aataattttt ctatttcttc taatatccag tatttgttta aatgcatacc
    12421 aaagcccacc tattgacgat attttttagg agtgaatttt ttctttgctt taactttggt
    12481 taaggcaagt gcaagttgaa tggcatcgta taatttttcc ttatcttcat cgtctaaagg
    12541 ttcaccataa taatttgttt cagcatctga attcaagcct tcaagtaatt tttcagcttg
    12601 taaagcaata tcttgtttat ctttttctgt taaatcataa taatggcgtt tatcagtacg
    12661 tcctaaaaga taatcagttg atacattaaa gtaatctgca actttttgta ttttatctcc
    12721 agatggagta cttttattcc atctagacat gcttccattt ccgaaattta actttctttc
    12781 aagttctgcc aacgtcattg aacgttcttt taataagatt tttatacggt ctaatagcat
    12841 aggatatgca ttcctttcaa aataccgaca aaaaaagtat ttttctgcaa attatctatt
    12901 tacaaataga gaatttgcag ttatactagt tttgtaagca agatatttac ggcatacaaa
    12961 gactaaaagc aataaactaa tagtctcccc agacatcagt aagctcgctt tttgtgcgct
    13021 gtattttgta tgcttacata atagcatatt tgcagttttt gtcaaactta ttagacaaaa
    13081 atattagaaa atattcgata agggggtatg aagcatgact ttaaaacagc aagtattaat
    13141 tgctttagta aagaaaggtt ggagtcaaag agagttagct cgacgaatgg gtatatcaat
    13201 tacttattta cgagatatct tcatcgaaaa aagaaaacct aaggaacgtt taaaacaaat
    13261 cgaagaactt ttggatatca agttagaagt agattctaat gatcagccat cagaacagga
    13321 ggcgtaaaaa tggtacaacg tttgagcaaa gcggagttta aagagaaata taagtattct
    13381 gaaagtactt atcaaagaag aatgaaggaa tttaaaaaat cacgttttag tgaggggtat
    13441 aacgcagtta cttccaaaga aataacaatt gatgtcgatt tatatgaaca gtttagaaca
    13501 tggcgttcta aaaatcgatt tagagttaga gctgtttgtt aatagctaaa aaatctaaat
    13561 tcaccacttc tgaaaagagg agttgctgct ctcctttcaa gtttgccaaa gtccacgttt
    13621 tttcattttg gcaactcctc ttcttggagg tggtgacggc gagagacgaa ggagggatga
    13681 catgaaggaa gaatcaaaaa tagggatttt gaatgagaac aattacacaa gattaattat
    13741 tgaaacagaa gaagggaaaa aagtagcaga agttacattg accgatgcaa ctcctgctga
    13801 cggttatcgt attcgattaa ctcctaaata tgattaacct tttggtgggt gtggatcgtt
    13861 tccgtgacta tcacggcttt gaatttttcc atctctgcca tgaataaata gctcagatcc
    13921 ttgattttta gaaatctctc tagcgatttt tactgcttct gattttgtat tagtatgtgc
    13981 agtcgcttta gaatttccag cacctttgac attccaacca ccattggaat taggtacaac
    14041 atgttgattt tttcccatag ttttcacctc catttctata gaaatatttt atcaaataga
    14101 aatggagaaa ttcaataaac gaaaggagaa gtgatatggc atataccttg caacaagaac
    14161 atcaaattct cggtttgatt aaacaacgca ggaaacaatt acaagatgac cgtgcagcgc
    14221 ttagaaaagc cgatgagcta tcagataggc aagctgaact aattgcttct gaacttgagg
    14281 atttgagaat gctagaaata aaaaataggg agattagatt atgaagaaga cagacacact
    14341 ttttatagga ttcattttgg ggttattagt gattgtagcg caccaaagta ttatcggggg
    14401 aagcttgttc gcagcattga tggttttaat caatctgctt gattcaaaag aaaggagcaa
    14461 ctatggcacg agaagaagcg ctaaaaatcg gtaaagtgat tgctgataat cggtggggaa
    14521 atagccgccc tattatttta agcaagcaac atatcgaaaa gcaaaaagca tggcaacaaa
    14581 taaaaaagtg actctgccag ccagcaaaga gtcacataca aatttataaa actaggagaa
    14641 ttatatcaca tgaataagaa aattgaaaat cttatcgaag aattgaaacg tgaatgccaa
    14701 aagcaaggtg tttctattat ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt
    14761 tatggtgaga caacagaaat tttactttgt cttgctatgc aagaagaaca tttagatgaa
    14821 aatctcccat tgtcagcaca tattatgcgt agaattgctg tggatgctta cgaacaagcg
    14881 aaaaatgaag aagaaaatca accttcaaat catacttttg ttattaataa caaggaagat
    14941 ttagctgatg tgatgactcg tattctcaag ggggaatttc aatgatgaat gaaaaaacaa
    15001 ttgatctact cattatttta tttttcacgt tagtgattgt agcgaaaagt tatgtaatct
    15061 ttggcttgtt attcgcaatt accatgcttg tgctttgcgt gttagcaagc agaaaagagg
    15121 ttaaacatga acgagttagc aaatcttgac aactatttaa ctgatcctga ttatgctaaa
    15181 ccaccatatg aagcaccaat tgatgaggag gatgaagatg agtaaatcta ccttagaaat
    15241 gagccatcaa gaatggcttg aagaccgtaa gaaaggcatc ggaggttcgg atgttggaac
    15301 aattttagga ttgaataaat ggaaatctcc ttatcaacta tggctagaaa aaacaggaca
    15361 agtagtactt gaagaatcag gaagtgagcc cgcttattgg ggtaatgttt tagaagaagt
    15421 ggttgctaaa gagtttcagg aacgtacagg caaaaaagta cgcagaagaa accaagtatt
    15481 tgaacatcca ttacatccat ttttaagagc aaatattgat cgggaagtag tgggagaaaa
    15541 tgccattctg gaatgcaaaa cagccaatca atttctcggt aaagaatggg aaggcgaaga
    15601 ggtaccgctt agctatctct gtcaagttca acattacatg aacgttctaa acaaagacta
    15661 ttgttacatc gctgtcttaa tcggtggtca aaaatttatc tggaagcgga ttgaacgaga
    15721 tcaagagctg atcgatacaa tcactgaaca attagtagag ttttgggaaa caaacgttct
    15781 tggaggtatc gagccaatta ttgatggtag tcaagcgaca gctgatttct tgaaagagaa
    15841 gtatgcagat gttgaagacg ttcaaacgac gttaccaatt catttcgatg aactagttga
    15901 acagaaaaac gaactcaaac ggactaagaa agaaattgaa tcagctatcc gtcaagtaga
    15961 caacgagatt atcagcgagc taggtaaacg tgaagccagt atcggtatca ctcaaaaaaa
    16021 catcatcagt tggaaatttg tccgtacgag acgtatgaac tcgaagaaac tagcagagaa
    16081 atatccagat gtcgcaaatg atgaagagat ttataacgtt actgaatcaa gaaggctaac
    16141 cgaaagggag atcaaataat atggcaacaa atgaatcgtt aaaaaatcaa ttggcagcaa
    16201 agccacagaa acaagttgca ccaggtcaat taggacttaa agctttgatg aatacaccaa
    16261 caatgagaaa gaagttcgaa gaggtgcttc atgacaatgc taatgctttt atgtcgaatg
    16321 ttatgactct tgtatctaat gacagttatc ttgcagatag tgaaccgatg tctatcatga
    16381 gtggtgcgtt aactgctgca acattaaatc ttgggctaga taagaattta ggttatgcat
    16441 atttagttcc attcaatagt aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat
    16501 tcatgcttgg ctataaagga tatatccaat tagcccaacg atcaggtaaa tacaaagcat
    16561 taaatgtgat cgaagtttac gaaggagaac taaaaagctg gaaccgactg acagaagagt
    16621 ttgagtttga tccaaatggt agaacgtctg atgaagtcat tggatatgtt ggctatttcg
    16681 agttactgaa tggattcaaa aaaactgtct attggaccaa acaagaaatc gaagctcatc
    16741 ggattgctaa caataaagat cgcgataaga caaagttaag tggtgtgtgg gcatctgatt
    16801 acaatgcaat ggcacgaaaa actgttttga gaaatcttct ttctaaatgg ggaatcttgt
    16861 ccatcgaaat gcaagaagcc accacatcgg atgagagagt ccaaagggtt caagaagacg
    16921 gcagcattat tgctgaaaca gaagttgaag aagatattcc tgaaagaaaa gaagcagagg
    16981 ttatatctga agaaaatgaa gatgtacaaa ctggattatt tgatgcatct aatccgccgt
    17041 taaacaaata atgagggagc tttctccctt gcttttctag aggagaaata cgaatgaaca
    17101 caggatatgt caaattacat cgaaaagtga tgaattcatt cgtttggacc aatccttata
    17161 tgtataaatt atggaacttg tgtttgatga aagcgagtca tgagaatcgc aagatacttt
    17221 ttaatggaaa agagatacaa gtgaacagcg gagaattcgt cacagggcgc gatgctatca
    17281 catctgagat gaacgaaggc gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga
    17341 gatggctaaa acaatttgaa aaaaacggaa tgttgaacat caaatcaact acgaaataca
    17401 gcgttatatc aataaaaaac tggtctttgt accaaagcag tgaacaacaa atgaacatca
    17461 aacgcacaac aagtgaacaa caagtgcaca caaacaagaa tgaaaagaat tataagaatg
    17521 aaaagaataa taaaacatca tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact
    17581 cagtttacta cattctcgcg gaggagttat tcaaacagat ttgtcagaat caggaaatca
    17641 aaaagccgaa tctgcaaagt tgggcagatg acattcggaa aatgatcgag atcgacaagc
    17701 ggaccgaaaa ccaggtacgg ggaatgattg aatggagtca gcacaatgtg ttttgggcat
    17761 cgaatatttt atctgctaaa aaattgcgag aaaaatacga cacaatggca gcgcaagcaa
    17821 atcgtgatta taaaacaaaa caaactaaaa cgcttgaata cgagaaattt agcacagatg
    17881 agttgcctat ttgagaggag gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct
    17941 gatacagaaa gtgcttgtcc aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg
    18001 atggcgtacg aagaaccctg atggctcaga acgttgtaag ccaacctgta tgcaatgtgg
    18061 gtataaagca ttgcgagttc aggaagactt acaaacagaa cgaatttaca acgagagcct
    18121 gaaagcaaga gcaatcaatt ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt
    18181 tgattgcaca ttgcagaatt atcaaattgt cgatcaagaa acaagacaag cggttgaagt
    18241 aaccaaacgc tttgttaatt cagtcttgtt aggaaatcca agtcaccttg ttttaactgg
    18301 aaaacaagga acaggtaaaa gtcacctagc gatggcagcg gcttgggaag tcttgaagcg
    18361 atcaaactac gataaaaaaa tcttatttat cgggttacag gaaatgctgg atcaaatcaa
    18421 attttcgtac aacaatcctg aactcagaaa aacgattgag ggatcgttga ttgcagatat
    18481 caaaacagcg gatttagtca tcattgatga tatcggttca gaactaggaa aagatgcatc
    18541 agatagtcga gcgtttggca taaacacgct aaattcgttc ttggatgcac gacagaacct
    18601 agcaacgatt atcacaacga acttgcttgg tgaagaactg aaaaaagctt acggtacgag
    18661 aacaatatca agaatgtttg tcaactctga tggatttacg atggtatttt ctcaaacagc
    18721 agacaagcgc ataaaaccag tcaaaggagc gatcgcatga atttgactaa acaagaaaaa
    18781 agaatctgtc gtcagataat gttgcaaatt ataggtgatc gtgacatgga cgaattatct
    18841 caacaagaga gtcgaatggt tcggaagata agtaagctaa ttatttatcg ggatacagaa
    18901 agatttctca ctgttttagg taacgtctac gagaatccag agttattgga ggtagagtaa
    18961 ttgccaaaaa tattagatgc atgttgcggt agtagattgt tctggtttga taagaacaat
    19021 tctgacgtaa catttatgga ttgtcgtcag cagtatgaag aattatcaac aggtcatgtg
    19081 atcaatgttg atccagatgt ggtcgcagac tttcgcgata tgccttttga agatgatgtg
    19141 ttcgatatgg ttgtatttga cccgccacac ttaagacatg tcggcgaaaa ctcatggctt
    19201 gccaaaaaat atggaaaatt agacgaactt tggccagaag acatcaggca aggttttgca
    19261 gagtgtatgc gagttttacg accttcagga acattaattt ttaagtggaa cgaggaacag
    19321 ataccacttt ctgatgtgtt agaggctatt ggagaacagc cattgtttgg taataaacga
    19381 agcaaaacac attggcttgt gtttatgaaa aaattcagct aacggaggaa acaaaggagg
    19441 aaaagtaatg aagattgtat taaataaatg ttttggtggc tttgggttga gccatgaagc
    19501 aaaaatggaa atttttaaaa gaaaaaatat tgaagtattc ccatacatca ataactttag
    19561 ctatgactca gatgatgaat acacgagata cacaggccaa aagctaggtt cgatggattt
    19621 tatctactat ttcaaaaaag acccgaaaat cgacaaagtt acaggaattt atagcgaaat
    19681 tgaccgactg tacggaattg ctgatgattc cagtttttca agtgattcaa acagaggtga
    19741 taaggacctc gttgctgttg tcgaaaaact aggaagtgag gccagtggac catatgcaag
    19801 tcttaaagtc gttgatatac ccgatggggc tgagtgggaa ataagtgatt atgacggcgt
    19861 tgaaactgca cattatggtt ttcaaacagg tagtatttag tccactaatg acaactaaag
    19921 aggaggcaga aggatgagtg aagatgaata ctttgaacag tagtctatta acgacagaga
    19981 tttttaactg gaaaggggtg tagtcatgga cgcatcggaa gtagtaaata aaattaatag
    20041 tctcaaagag gttttcggag acgtcgaagt agtgataaac gcacaaggct atgacaacga
    20101 attttttaag cagattaccg acattagcat tcagcaagga atggaagacg aagacggaaa
    20161 ctttatcgat gaagtagcca ttttagtgac ttgcgagtaa gtaattgaca gctaaagagg
    20221 aggaagcgga atgaaactaa aagacggatt ttactccagc ggccacggca tcggcggttt
    20281 aatgctagat atgccgacaa agaatcctaa aacacgtaag aaaccaaaat tcaaagtcgg
    20341 tgacatggtt cgctgcgaag cagaaggatt catctatcca tttcgtggat atgtagaaca
    20401 cgtctataat cactcagcaa tcattcgcat tgaaaacacg atggaatgtg ataagtggtt
    20461 agcgaaaagc aaagagaatt tagcagtggt gagattggtg gacatggaag ttataaaatc
    20521 ttaattttgc ttttttacaa ctatcctaca acaatgagcg ttattccaca actggaagga
    20581 gaagaggcaa ttgtgaacat tttagagaat atagatatta agcaaacaag gaaaaatgct
    20641 agacgattac taaaaagata cagaaattta gaacgtttgg tcggaccagt gaaaatagac
    20701 ttttccgtga tgactgttac caaaaatttg aaattcacaa ttgacagtca aaacgaagaa
    20761 atcattgaag cgataagtac tcgagattcg gttatcgaag cattaacacg gctaagtaga
    20821 atccatttcc aggtacttta ttatagttat tgttttccta ataagatgtc aatgtatcaa
    20881 ataggagaaa aattaggata ttccgataga actatcgaga gaatgaaggc agtagctttg
    20941 gttgaatttg ctgaggcgta taaatcagga gaactcattt cacgtacaaa ataaaaaaag
    21001 tcggattcct ccgactatga ataatatttc cgacataagt attatatcat aattggggga
    21061 atcagaggat ggtacttttc gatgtaaaga aatatgagac accaagcgcg aaagatgttg
    21121 atatggaacg cacaaaacat aatgtcgctg tgtttctttc agcatatcta tcagctagat
    21181 gtagagtagg gcaacatc
//
LOCUS       DASHXG010000045        20943 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.046, whole genome shotgun sequence.
ACCESSION   DASHXG010000045 DASHXG010000000
VERSION     DASHXG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.046"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            169..363
                     /locus_tag="U2R59_001984"
     CDS             169..363
                     /locus_tag="U2R59_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966356.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            632..931
                     /locus_tag="U2R59_001985"
     CDS             632..931
                     /locus_tag="U2R59_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966357.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1028..1462)
                     /locus_tag="U2R59_001986"
     CDS             complement(1028..1462)
                     /locus_tag="U2R59_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966358.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1694..2404)
                     /locus_tag="U2R59_001987"
     CDS             complement(1694..2404)
                     /locus_tag="U2R59_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEM8966359.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2394..3254)
                     /locus_tag="U2R59_001988"
     CDS             complement(2394..3254)
                     /locus_tag="U2R59_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEM8966360.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3259..3897)
                     /locus_tag="U2R59_001989"
     CDS             complement(3259..3897)
                     /locus_tag="U2R59_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEM8966361.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3912..4211)
                     /locus_tag="U2R59_001990"
     CDS             complement(3912..4211)
                     /locus_tag="U2R59_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8966362.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4254..5738)
                     /locus_tag="U2R59_001991"
     CDS             complement(4254..5738)
                     /locus_tag="U2R59_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEM8966363.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5758..6219)
                     /locus_tag="U2R59_001992"
     CDS             complement(5758..6219)
                     /locus_tag="U2R59_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8966364.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6237..7304)
                     /gene="ulaG"
                     /locus_tag="U2R59_001993"
     CDS             complement(6237..7304)
                     /gene="ulaG"
                     /locus_tag="U2R59_001993"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEM8966365.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7522..8292
                     /locus_tag="U2R59_001994"
     CDS             7522..8292
                     /locus_tag="U2R59_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEM8966366.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8565..9392)
                     /locus_tag="U2R59_001995"
     CDS             complement(8565..9392)
                     /locus_tag="U2R59_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966367.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9960..11195
                     /locus_tag="U2R59_001996"
     CDS             9960..11195
                     /locus_tag="U2R59_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HEM8966368.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12194..12454)
                     /locus_tag="U2R59_001997"
     CDS             complement(12194..12454)
                     /locus_tag="U2R59_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEM8966369.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12481..13782)
                     /locus_tag="U2R59_001998"
     CDS             complement(12481..13782)
                     /locus_tag="U2R59_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8966370.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14074..14532)
                     /locus_tag="U2R59_001999"
     CDS             complement(14074..14532)
                     /locus_tag="U2R59_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8966371.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14545..15876)
                     /locus_tag="U2R59_002000"
     CDS             complement(14545..15876)
                     /locus_tag="U2R59_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HEM8966372.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15887..17329)
                     /locus_tag="U2R59_002001"
     CDS             complement(15887..17329)
                     /locus_tag="U2R59_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8966373.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17316..18080)
                     /locus_tag="U2R59_002002"
     CDS             complement(17316..18080)
                     /locus_tag="U2R59_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HEM8966374.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18184..19059)
                     /locus_tag="U2R59_002003"
     CDS             complement(18184..19059)
                     /locus_tag="U2R59_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8966375.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19314..19398)
                     /locus_tag="U2R59_002004"
     tRNA            complement(19314..19398)
                     /locus_tag="U2R59_002004"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19362..19364),aa:Leu,seq:caa)
     gene            complement(19416..19487)
                     /locus_tag="U2R59_002005"
     tRNA            complement(19416..19487)
                     /locus_tag="U2R59_002005"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19453..19455),aa:Gln,seq:ttg)
     gene            complement(19497..19569)
                     /locus_tag="U2R59_002006"
     tRNA            complement(19497..19569)
                     /locus_tag="U2R59_002006"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19534..19536),aa:His,seq:gtg)
     gene            complement(19631..19715)
                     /locus_tag="U2R59_002007"
     tRNA            complement(19631..19715)
                     /locus_tag="U2R59_002007"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19679..19681),aa:Leu,seq:caa)
     gene            complement(19736..19806)
                     /locus_tag="U2R59_002008"
     tRNA            complement(19736..19806)
                     /locus_tag="U2R59_002008"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19772..19774),aa:Cys,seq:gca)
     gene            complement(19852..19923)
                     /locus_tag="U2R59_002009"
     tRNA            complement(19852..19923)
                     /locus_tag="U2R59_002009"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19889..19891),aa:Gln,seq:ttg)
     gene            complement(19935..20007)
                     /locus_tag="U2R59_002010"
     tRNA            complement(19935..20007)
                     /locus_tag="U2R59_002010"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19972..19974),aa:His,seq:gtg)
     gene            complement(20010..20083)
                     /locus_tag="U2R59_002011"
     tRNA            complement(20010..20083)
                     /locus_tag="U2R59_002011"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20049..20051),aa:Trp,seq:cca)
     gene            complement(20090..20170)
                     /locus_tag="U2R59_002012"
     tRNA            complement(20090..20170)
                     /locus_tag="U2R59_002012"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20134..20136),aa:Tyr,seq:gta)
     gene            complement(20172..20247)
                     /locus_tag="U2R59_002013"
     tRNA            complement(20172..20247)
                     /locus_tag="U2R59_002013"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20212..20214),aa:Phe,seq:gaa)
     gene            complement(20283..20355)
                     /locus_tag="U2R59_002014"
     tRNA            complement(20283..20355)
                     /locus_tag="U2R59_002014"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20320..20322),aa:Asp,seq:gtc)
     gene            complement(20365..20437)
                     /locus_tag="U2R59_002015"
     tRNA            complement(20365..20437)
                     /locus_tag="U2R59_002015"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20402..20404),aa:Val,seq:tac)
     gene            complement(20453..20524)
                     /locus_tag="U2R59_002016"
     tRNA            complement(20453..20524)
                     /locus_tag="U2R59_002016"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20489..20491),aa:Glu,seq:ttc)
     gene            complement(20539..20628)
                     /locus_tag="U2R59_002017"
     tRNA            complement(20539..20628)
                     /locus_tag="U2R59_002017"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20592..20594),aa:Ser,seq:gga)
     gene            complement(20668..20741)
                     /locus_tag="U2R59_002018"
     tRNA            complement(20668..20741)
                     /locus_tag="U2R59_002018"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20705..20707),aa:Asn,seq:gtt)
     gene            complement(20751..20866)
                     /gene="rrf"
                     /locus_tag="U2R59_002019"
     rRNA            complement(20751..20866)
                     /gene="rrf"
                     /locus_tag="U2R59_002019"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6603 a         4390 c         3331 g         6619 t
ORIGIN      
        1 ttaagaacaa tagcctttta ttatatatat tattcaaatt agttatatcg agtgaaaaaa
       61 actttcaaat tgattctttt tatttatcat aaagatatag atacataatc attttcactt
      121 acatatattt gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta
      181 gaagtaaaaa caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat
      241 cctttacttg gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata
      301 aagaacgagc tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag
      361 taaatccaat gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat
      421 tatagaatta gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata
      481 ccatatgatt atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat
      541 gaatcaaata tacttgtcat tcatcatgaa atatagagac ttataaaatt gtttattttt
      601 ataatgtatc agtatagaaa ggaaataaaa catggattat actgttgaat ttgacagtga
      661 actacttaag caatttccac aagaagaaca tttcatgtat aaagaagcaa tttcccacaa
      721 agtgacagag tatttggagc ataatttttt tcgtataaag ccagtgcgta ctcgttcggc
      781 aaaaggaata tacgagatga aagtcaaaat taataaaaaa aattatcgca tagcatttgc
      841 tttaaaaaaa aatcatgtgt tcatttttta tattagttcg aatttgcaaa aaattgtatt
      901 tgataaagag gtgagtaaaa aaataaaata gctgagcatt ggaggataga ttgagtgata
      961 ctaagtctat cctcttgttt ttctaaagaa ctaagctaga attttttctt ttgtacgtta
     1021 ttatatgtta tttgtcatta ccaaaaagca ccttttttct tctagtatct atgacataag
     1081 aaataccacc catttccttt acttgaacaa atcctactga ttcataaaat ttttttgttt
     1141 tctcagtatc atctgtcaat aattcgattt ggactggtcc ataactagtg atcttctcca
     1201 aagcttcatt caaaagcact ttgcctattc cttggcgctg atacctcgga tgaatgagga
     1261 tatcttgaat aaatgcgatc gtcgcaaaat cagtgatcca acgaacgatt ccgataatct
     1321 tcccttcccc attacgcttt atcagagatt cagattgttc aaatgctcta gctaaccttg
     1381 cagtgtcttt tgtgtaattc gtccaaccaa cgctcttata taattcagaa atctcatcga
     1441 tcataaggga atcaatattc atttttttct tcctttctta tacaattctc cctctaataa
     1501 tacagttctt tgactattta atctatcaca tataactctc ctgtaaagat tctctcgatt
     1561 ccttaaaatt cctctttcct tttagaatgc atactttttg ataaataaaa aggttgtgat
     1621 aaattttctt cacaacctct gtttctctct atcaagtgtt atcttttaat tttctaccct
     1681 taccctagca tctctattgc ccgtagtatg catactttcc atgtttgcga aaataatgtt
     1741 tatctagtaa atattgcggg atttcacata tattggggtt gatcagctcg ttttctttgg
     1801 ccatcagaca aatttcatct aagatcaaac tgttttctac tgctttcata ggtgaatccc
     1861 cccatgtgaa cggtccatgt ccatagacaa gtactccagg gacttcgttt ggatctaatt
     1921 ttctttcctt aaacgtctcg acaatcacat tccctgtatg aacttcgtaa gcttctctta
     1981 cttcttcttt cgttaattgg cgtgtacaag gaaccttacc ataaaaagca tcagcatgag
     2041 tcgtgccata agctggcaaa tcgcgtcctg cttgcgccca catgacggag tgcgtggaat
     2101 gagtatgagt aatagcagtt atatcttcaa aagtttgata caaaacaaca tgtgtgggga
     2161 gatctgaaga tggttttaag ctatcttctt ctattatatt tcccgacaaa tctgttacca
     2221 ccatttgatc tgcttgcatg cattcatatc tgacaccgct tggcttaatg acgatgactc
     2281 ctagctcacg gtccacttca ctcacattgc cccaagtcaa tttgactaat ccgtatcgcg
     2341 gcaatgccag atttgcttca aggacacgtt gcttcattgc tgcaattttt tcttcacaag
     2401 acatcatagc cagcctcctt caatttagaa cttaagtagt cttttgcctg ctggatttct
     2461 cttcgaaagt cttggctttt ttcactccac atttcaatca gaaatgttcc atcataatct
     2521 agacgtttca aatgtcttaa taatccaaga aaatcaacac aaccgctacc aaaaggaaca
     2581 tcacgaaact ggcctgaata ttcttttgtt acagggtaag tatcttttaa gtggatagca
     2641 gtgatataat cgatcccttt ctcaagttct cgagccggat tattttccgg ccatgcggac
     2701 aaattgccta ggtctggata tacttgtaga aaaggtgaat gaatctgttc tttgatttct
     2761 aaaaattttg aaatggagtt cataaatgga tcatccatga tttccacgga aagaatgatg
     2821 ccatatttag aagcttcctt tacgctttct tttattcctt cgataaagtc ttctctggaa
     2881 ttcattgatt tctcttcata ataaacatcg tatccagcta tttggattac tttgacgctt
     2941 agattatgcg ccaaatggat tgcttttttc attagttgtt tcgctgcttt tttcttttct
     3001 ggatcagcag aaccaaacgg aaatcgccga tgcgcactta aacaaatcga atggatacgt
     3061 acaccggagc tgaacatctc ttctctcagc tcagctatct tttcttcaga ccaatctaat
     3121 cgtgctaacc gctcatccgt ctcatcaatc gacatctcga taaaatcgaa gtccatttct
     3181 tttacaaggg aaaaacgttc tttccatgaa atatctttgg gtaacgcttt ttcataaatc
     3241 ccaatttgag ccatttcctt acccccagat acgaatgatc tcatctttga agttttgtgc
     3301 ggccttcatc ggatcatttg ctgctgtaat accacgacca gtgataaagg tatacacatc
     3361 gatcccttca aataagtgta atgtgtgtgg atttaatcca ccagttacag aaacattaaa
     3421 gcctagttca atcagttttt tgatcttcga taaatctttt tcaccccaag tttcaccaga
     3481 taacagcgca tcacggcttt gatggtagat tacctgccgg ataccgatgt tatgccaatc
     3541 catggcttgt tcaaaagtcc aattgccgta gagttctact tgcaattcac ctatttcttt
     3601 ttgtgctgcc tccatagttg gaatcgttgc acaacaaatg actgtcatcc agtctgctcc
     3661 tgcttttgca acattactcg ccactgttcc tccagcgtct gcacatttcg tatcagcgac
     3721 tagtttttta tctgggaaca tactgcgaat acagcgaatc gctttttgtc cttcctgtaa
     3781 gcaaagaatt gtgcccactt caataatatc tactacatca ccaactttca taacatctcc
     3841 taatgcatgt tctaagtcat tgtgatctaa cgcaatttgc aaattcggcc tgctcatctt
     3901 agttccttcc tttacttgtt tttttggtac cactttgttt cagcaaattt ttcactgatt
     3961 tctttgactg acatcacatt tttgataccg ataactgtaa ctcctttttt ctctgcctga
     4021 gtaaacatat tcaaaaaatt gactggcgta aaaactacat cgtattggcc agctgaactt
     4081 tttccctctg aaatggcaca atgatggatt ttggtaattg gtacgtttag ttctttcatt
     4141 gctttttcca cacttctcat catcatcaag cttgttcctg atccatttgc acacgatact
     4201 aaaattctca tcttaatccc tccattatga gtgttgtcta atcagatttt cttttatact
     4261 ctctgctttt ctgcatatgt gtcatagtct tctacaatca aaaaataacc atcaggattt
     4321 ttccgatatt gtaactgcgg aatagccaat aaaccaatga caactacggc aattccagca
     4381 taacctagga ctttcatgat tactgtaaac aatggccaag ctgttgccca gtcgaacatc
     4441 ccgatataac caccgtatgt tgacatccca atccatgtag cgaataatgc tgaaccgcct
     4501 acttgtatga ttcctgaaag aaacgggaac aggcaagcgg ctttgaatcc acctcggtta
     4561 ttggcataaa ctgctataac ggcattatca aagaacaacg gaatgaaacc ggctatgacg
     4621 atcgttggtg atttcaataa aatcagtaaa ccaatcatca aaaactgtcc caaagcacca
     4681 aacaagaacc caatcgttac cgcatttggc gaaccaaagc caaaagtagc agctacgtca
     4741 attcctggaa cagctcctgg taaaatcgtg tttgagattc cttggaaaga ttgagttagt
     4801 tcatcgacga atgtccgaac acctaattgc aagatcgcca gatataccgc aaaatttaaa
     4861 gaagtcgtca taatgtagaa taagaaactc tgcccttctt gcatgaattg cgcttgaatc
     4921 aaataatctt tgcctagtac aatcagaatg atcccaaaga aaaatagcat gagtaacgaa
     4981 gtagcaacca tattctcatt gaaaatcgac aagaatcctg gtaatttgat atcttcaatt
     5041 tttttgtctt gcttgattga tctatttttc ttttcatccc gctttttcat ccactcagct
     5101 aattttgcaa atataaagat tccgaacatt tgctgatgtg ccactgcaaa tccggcacct
     5161 tctgtcaatt cctgcgtgat tcctactgtt aagttagaag ctactgtcca ataacaacct
     5221 aaaatcagtc ccataaaaat caatgcttgt atcctaccta gatcaggaaa gcaaaacagt
     5281 aaaatccaaa aagcggtagc tgcttgttga acctgaacgt ttccggtagt gaaaacggaa
     5341 cgcagtttcg tatatttctg aaaacggact aataagatat ttaaaacaaa tgcaatcagt
     5401 aataaaatca tcacatctcc aaaggtacgg ccaaatgtct ccattaatcc agcatccaca
     5461 gcattttgtc caaaataagg atctgtaacc atggcatcca aattgaaccg ttcctttagt
     5521 ccaaccaaga ttggccgaaa attattgacc aaaccaccag agccaacagt caaaataaag
     5581 taaccgaccg ttgcctttaa gaatccagcg atgcattcat gaagcgggcg tttcagcaaa
     5641 atatagccta ataacacgat aaaaccaatc aggtatgctg gctgcgtcaa gatatttgtt
     5701 gcaaaatacg tccaaatgct taacaaaaat tcccccatct tttttctcct ctatcaatta
     5761 attatattct gccatcacaa cttggtaatc atcgatggag ttcgtagaga tgagacgctc
     5821 aaccaatcca tctgtcatta ataattcgga taatttttgg atattttcta gatgttcttc
     5881 tggatctttt gctgcgagtg taaaaaacaa actagccgtt ttctcctcat tctccccttc
     5941 actttcaaaa cggattggct gtttcaactt ggtaaatgaa atagctgttc caaaaacacc
     6001 atcacttttt tctgaagaat gcggcattgc tacttgaggt gcgatcacaa tataaggacc
     6061 gtatttttct acacaatgga tgatctcctc cacatacgtt tcatcaataa tttccttatc
     6121 gatcaataca agacagcttt cggcgatagc ttcacgccaa tccgtgattt ctttatctgg
     6181 gtaatgaatc aattgatggt caaaaaagta tttcagcaag aaactcccct tctttcttat
     6241 aaaaacgacg gaaacggtgt atcattttca atcgagaaga catcttcaaa tcctcgataa
     6301 aaattaaact caagatcatc tttgtttgtc ggatagatga atttcccgcc tacttgccag
     6361 atataaggtt taaatccata cttcaggcga tcctttttga atttccaaat ttcagtgatc
     6421 tcttttggat cagccataaa attagaccaa atatcgtagt ggacaggaat cactactttt
     6481 gcattcaatg actccgccat gcgcagcata tcaacagaag taactttgtc tgttatccct
     6541 cgtgggtttt caccataggc ccctaaacag acatcgattt tgtgttcatt accatgtttg
     6601 gcaaataaat tggagtaatg tgaatctcct gcatgataaa gattccctcc tgatgtttcg
     6661 aataaatagt ttactgcaat ttgatccatc tcctgaggca tttttccttt taatacctct
     6721 tctggatctt cacaagtgac caacgctgtc cgatcaaacg cttctaaagc tactacattg
     6781 atgtctttga ttttgactgc atcacctggc tttactgtaa tcgttttttc ttcaggaatt
     6841 ccccattttt gccacgtgcg aaccacttct tttggcccaa tgaatgttgc ttcaggacaa
     6901 ttttgatgaa ctgctgcggc tgtatggata tctagatgat cggaatggat atgtgtaacg
     6961 attaaagcgt ctacattttt tatcgcaaaa ggatcgatta cgaaaggctg agtacgtaaa
     7021 ttaggctgca tattttgaac gccactcata cgcatcatct gatggccttt tttcatcatg
     7081 ccattcccat gactacgttt tcccgtccca caccatagat cacataaaat attcgttcct
     7141 tcatgacttt tcagccaaat tcccgtacag cccagccacc acatagcaaa agttccagga
     7201 tccactactt ctgtttcgat ttcttcattc aagtatgtgc cccactcagg aaatgtttct
     7261 actaaccact tttcttttgt tacttcattg acagttttac tcatttgctt gctcccccca
     7321 tatcgttgtt ccaacttaca agtaaatatt aatgtgtatc agcatccatg aaaacccttt
     7381 tatatgaccg tttgtttttt atatgatttt ctttcagtaa tcaatgattg tttcagtata
     7441 ataaagacag atatgaatgt ttaaatgaac aactagtcaa ataaatccat ggatcaagat
     7501 gtccctcagg aggcaaaagt catgaaaaac tcacttgtca atattgaaaa acgtcaaaaa
     7561 gaaattttgg aactgcttca gcagactgaa caactatcaa ctttcgaatt agctgaatcc
     7621 cttgatgtat ctattagtac gatacgaaga gatttaaatt tattagaaga aaaaaacgag
     7681 atcatacgca attacggtta ttgttcttat aattacaaaa accagactga ttttgatcaa
     7741 tctggtcctg aaaggattaa acaagcgatt gccagagaag ctagtaaata cattaacgat
     7801 tatgatacgc tgtttatcaa ttctagctcg actgcgttga aaacactgga ttttcttcaa
     7861 tctaaccatt tgacagtcat tacaaacaac gtgaaaatca attactctcc gcacaaagat
     7921 aattgtagtt atattttaac tggtggagag atgcgctttc caaaagaagc actagtgggc
     7981 gacatcgcat taaatacgat ttcttcagtc aatgcagaca tttgtatcat tggctgtagc
     8041 ggagtcgatg tagtacatgg ggtcacaaca aagatattaa atgaatcaac gatcaacgaa
     8101 atgatggtca acaagacaat caaatgtaag attttagtcg ctgatcatcg aaaaatcgga
     8161 ctgacatcaa agttcaagat tgctgatatt tcagtctttg attatttgat cactgataaa
     8221 ttttgttctg aaaaagtatt agaggagatc agaaatacgg ggataaaaac cattcaagta
     8281 gattcatttt aagaaccagg acgtaaatat gtaaatagga ttatcaaaaa aatgaataac
     8341 aaatttatcg ataaatgaaa aacacgctac gctcaaattg ataaaggaat cccaagatgt
     8401 atccatccaa tcgataccat cataatctat tgcttctttt ataaccgtta tatgttgcct
     8461 aaataggaat caaacaatat cgaaaaaagg aggtatgaca aaagtcacac ctcctttttt
     8521 cgaataaacg gtattcaaat cagaacactg atttcacaac cactttattt caggtcgttt
     8581 tcaatcacct ttaccgcgta atcatttccg ttgaaacgcg ctattttttt tgcgtccata
     8641 tatctttcta aataatcatc ttctcctaat tgcttatggc aagaagcaat ttcataaagc
     8701 aagtattcca atgcataagt cgatttatgt ttcttattat actcaatacc cttctcacat
     8761 aattggattg ctttatcata atcctcgatt ttacggtaat aggtggcgat atcataatat
     8821 acaatgcaga ccatcagatt atcaaaatca gtctcactca atattttaag tgtacgctcc
     8881 acataaactt tcgcaaaatc taattctcct tttgacaagt agatcattgc cacgtttgca
     8941 gctgcttgta agtgatggat atctgtttcg gtcgtttgtt ccaacacttg attaaaataa
     9001 aataatgctg catctggttt tttcgcataa agatgatcaa gcagtccttg ataaaataaa
     9061 atttgattta aaagatcaga attacttact ttttcctgat cgatcgtttg taaaatttta
     9121 taagattctt ggtattttga tacagaattc aatgattgaa tctcatttat ttttttcctg
     9181 attttgtctt cttctgtttc tactaatata tcggagatct cgacattcag ctttttgcaa
     9241 agcgcactta agatattgat gcctggcgac atattcttgt tttcgatatt gctgacagtt
     9301 gcttgttcac aaatgccttc tgctaattgt acttgtgtta accccttttt ctttcggtat
     9361 tcttttagta atgctccatc tactttaatc aaaacaattt ccttcccttt aaaaaattat
     9421 ttctccttta tatcatacac aaaaaaaagt tctaaacaac caaaaatgtt tagaacagaa
     9481 taaaaatttt aattttaaaa taatattcaa attaaacaac tggcgtatct gctccttgat
     9541 ttctttttgt gttatctgaa taattatcgt ttacagttat aacacatagt gaaaattgtc
     9601 atggcgagaa agtctaagaa tatttttaaa cataactatt tctttcttac gtgtgtataa
     9661 tgacgacagc acacctatca attaatataa ttattttatt tttttatgtt ctcatgttta
     9721 tttttaatga cacaacttct cgtatttatc tggcacaaca tataaatcga tcaaaaaatt
     9781 gttgcgtgtt tttttgaaaa ttggagtttc aacttgatta caaaatttaa atttagaagt
     9841 tgtgaaaaca gcgagagaca gtttaatatt caaaatatac ataggctact cgaacgctgt
     9901 gttttttagt atactagtaa gaaacgaagg gatagactca ttccaataag gaggatttca
     9961 tgaagacaat tctttttgct cctgcagtat tcaatttagc tgagacaaca cgaatgattg
    10021 aggttgccaa agctatgaaa gaccgttatt actgtgtatt ctttggcttt tctaaaactt
    10081 ttgctccttt gatcacagaa agtggctttg agtatcattt actagcgccg atccttacga
    10141 aaaaacaaga agaacaaatc ataaaatttg accagttgcg tacacttaaa aaccctttta
    10201 ccaaagaaat ggttgcctct cgtatcacta gtgaacagag tctgattgct aagtttgagc
    10261 ctcgactgat tgtgacaggt tcgaatgtga caattttttt atcggcccgc aataaaaaga
    10321 ttcctttagt atatgttaaa ccctatgctt tgagtgaacc tttttttcaa tcagagcatg
    10381 cgctgatgcc ccacgagtta cgtttcttcg gccctttaag caatcccctt tggcactgga
    10441 caaaaaagcg tatagtaaat acccgatgga tccccaatgc cttcaaacac gctgcacaaa
    10501 aagaaatgct tcctttacca aaaacaagtt tacaaatgat ggatgctgat ctaaatctca
    10561 tcacaacgcc taaactattt ttggaagaag aacagctgcc ggaaaattat cgaatcgttg
    10621 gtccaatttt tgctaagctc agtacttcct tgcctgaaga agtgctaact tttatacagc
    10681 gaaagcaaca agaaagaaaa cgtattatct atttcgcaat gggtagttca ggcaatccgc
    10741 gtatgttacg caaaattttg ttcttcttac aaaaacaacc ggatctagcg gttattgcac
    10801 ctattgacta tctgcttgat gacattcaat ctgactcaga agatctttta ataacagaat
    10861 atctgtctag tcatcttttg catgaattca ttgatttttc ttttatccac ggcggggaag
    10921 ggaccgtcca aactgcctgt gaatccggca aaccgtttat cggtgtgggg atgcaatttg
    10981 agcaaagctg taatattgac tattgtgtaa aatacggaaa cgcaatcgcc ctcacaaaac
    11041 cagtgactga aagaaaactg cagattgctc tgcgcgaagt ttcttcaccc aagattcgtc
    11101 agcaggcacg cacgctgcaa gccgtttttc caataaatgg tccacaacaa gcaattcaag
    11161 aaatcgaaac cttcctgagc aaccacccaa tatagtttca agtagaaaaa gcttttttaa
    11221 tagagactca tcagtaattt cgctattcga gacccagaca gtgaaaatac aaaaaaagta
    11281 aatagtggat tgaaaagtta gagttactta aattacggtg tctaaaaaac acaaaatcat
    11341 ccttaaaata aaagatctga cgctatccaa atgagcatag gtagcgtctg ccatttattc
    11401 ttagtcaaat tctttgacac ctttctctgg ttggatcatc tcaacgtttc ttcaaaagaa
    11461 agaccataat aattaggcaa atacattttc ttaaaatgtg tcatatagat ctagaagcat
    11521 cgctttgtag agatttgtgc cgctagtccc ctcaacaatt actaaatcaa atgtaggatt
    11581 taccacttta tctttgataa tcaacctccc tcttctgttg agacaatgat ctcgcaatcc
    11641 gatgcatact cctatataaa ctgccagcaa tccccacata ttgagtagat catgtcagaa
    11701 tgttctatgt cgtcagcaac gatacactaa aagtcacgtt caccatgact gattgctatt
    11761 cccagcacaa ttatttctat acacgtttca tgatttgaat aaacactcac atcatacata
    11821 ttaccattca tacaccatac tgcagcccct actatatggt tgtaagctcc caaatctata
    11881 tttgacttga tcactttggt agtagatcta ctaattctaa atccattgct gataaaattt
    11941 ccattttttc ctccttcttt ctgccaaaac agttaaaaca ataataatct ttatgtaaaa
    12001 aagggctgtg acaaaagcct tgtcacagtc ccatattccg aataaacggt ggtcaaaagc
    12061 ttgcatctgc ggtaataagt tcaaccaaac gaaaaataag ccaacatttc acaaaaattt
    12121 aagaagcaat tttcgtaaat ttcttcttat ttcttgaagc taaccacttc tgttacaacc
    12181 acttttagaa catttaaagc ttcgatgtga caaaccatct atgctgctcg atcataaaat
    12241 tgatagcaaa aattccacaa agtacatatg tcccccatga aaacaaaaca ttcatatgcg
    12301 gtacaatgat ctttggaaga atcacgatca aaaatgatgc cagtgcccaa atccatcgat
    12361 tgatttgaat atgatatgta gctagcatat tcaatataag gtgactagcc gttaataaaa
    12421 agataaaaac aaaaaataaa atcagccaat acattgtttc ccaccttcta aaaaccaaac
    12481 ttagacagtc tggacttcgt tttctccacg actttgttca tctgacagca tctttttatc
    12541 ataagctttt acaaatggat aatagataat aaatgctatc aatgtgttga tcatgatcaa
    12601 gataacaaca cgccagtcat ttcctgctga aagataaccg ccgattggag ctggtaatgt
    12661 ccatgttggc aaaacagtaa atctattgac catttctaat ttgactgcaa aataactgat
    12721 aatagtcaaa actaaaggaa ctaagttgaa cgggatgaac atgtaaggat tcaacatcat
    12781 aggagctcca aaaattatgg gctcattgat attgaagata ccaggaataa tagaaaaacg
    12841 accaacctct ttcaagaatt ttgatttaca gaagaatata aacaaaacag ataccacgat
    12901 cgttgctcct gcaccaccaa ttgttaccgt ccattgataa aactgttcag gagcgatata
    12961 gggtaattgg gtggcagctg taccatctgc caatgccttt gcattctcat ccaacatgat
    13021 cagccacatt ggacgaacaa cagcccctac aatactcatg ccatggatac caaatgacca
    13081 caacaaatgg atcaaaaaca ttggtagtaa aacaccaagc aaattattcc ctaaaatatt
    13141 ggttaaaggc tcgaataacg ataataaggc agcgtttaca tcaaagcccg cgacgcttcg
    13201 aatcagccaa gtaattgtta aaatgactgc acctggaatc aatgcctcaa aactacgggc
    13261 aacagcaggt ggcacttgtt ctggcatttt gatagtaata tttcgatttt taaagaaacg
    13321 atatacttcc actgcaaaaa tcatagataa gatccccgca aacatcccag atgctcccaa
    13381 agaactcata ggtaagaccc agccaagagg tgcctcttca ggagttaaaa cgtttacagg
    13441 aacttgtaac ataaagaacg ttcctaaaga taatatacca cctgtcacac tatctaatcc
    13501 atatgattta gctagatccg aacccataac aaaagttgca taaatagcca tcaatcccat
    13561 cgtcatccta aagggtaaaa caatcgttgc cgaataaggg gcaataaatt cattccatcc
    13621 aggaaacggt aaattgataa agaccataaa aaatgtccca atcaaaatca atgacaatgt
    13681 tgaaacaacc ccattacgaa ttgctaataa atgacgctgt gtaccaattt ttgccattgg
    13741 tgggacaagt ttctcttcga cccatttcat cagcttttcc actaaaacca ctccttttca
    13801 ataaaatatg aaccattcat tgcatgacaa cgcaaagaat gttcataact aattatataa
    13861 ttaagaaatt ttatttcaat atattctctt aaataatcaa atttattttt aagaatcctg
    13921 aaaataagtt ttctaaatca taggagcaac aaaaaaattc gataattaac aaaaatcaaa
    13981 atgattaaat ctagtgattg aaacatatca tttcaaaaaa attttgtaaa ttcacccata
    14041 aatatcaccc tatttaactt ttttcatcgt acactaaaat tcaaaacaac tatctttaat
    14101 ctttacttct tggttttgtt ttaataaatt tccttcaaaa atgcctggag aaactacaat
    14161 gatcaccgta tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt
    14221 cccttctttt acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc
    14281 aactgtatct aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat
    14341 ggcatgtcgg gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc
    14401 atcatgattc gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt
    14461 tactgctgtt aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt
    14521 aaagaaatgc actttttatc acctctactt taatgctggc caatattttt tgtttacttt
    14581 gatcatttca tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt
    14641 aaatgcttgt aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc
    14701 tactgcaact tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt
    14761 aattggctcc acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg
    14821 tagattcgga atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt
    14881 caacaaggaa atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa
    14941 tacttcttcc acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg
    15001 tccatccatg accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc
    15061 aggatataag taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat
    15121 gactgacatc atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac
    15181 ttgcatttct tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc
    15241 tttatcataa atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca
    15301 attcttacga tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc
    15361 acaggcatta atcattttta cattcggata tttacgacga acagcttcag aaacgatcga
    15421 ctctggattt gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac
    15481 aatttccaat aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt
    15541 ttcttgtcct actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa
    15601 tcctccaaca cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc
    15661 atccgttgca cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat
    15721 caagtacata tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg
    15781 caaccgtttt tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc
    15841 tccagctata gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata
    15901 atttattgaa ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt
    15961 tttcagttgg tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca
    16021 tggtgggatc cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat
    16081 tggcttttcc tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg
    16141 ctaaccctaa ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac
    16201 gtcctaatgt ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg
    16261 caaaaaagaa aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga
    16321 tgagataatc aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac
    16381 agacaatccc tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa
    16441 acatgaaact aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc
    16501 ttcccatgat tcctttgacc atctctttat tttctttata agctgcttta tagatagcta
    16561 gacatatagc tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag
    16621 cctgaggatc tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag
    16681 atgtatagct tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg
    16741 ggatcagcaa acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga
    16801 gcagttttgc aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa
    16861 cagctgcgat tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat
    16921 aagaaaaaac tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta
    16981 aaccggaaat aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc
    17041 cttttttcaa ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat
    17101 ttttgacaaa accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg
    17161 catttccagc tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga
    17221 tcaatcccgc taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca
    17281 catttgattt aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac
    17341 tcaatcaaag gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact
    17401 tggtgggtac gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct
    17461 gcgtgacaca tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa
    17521 tattcttcca cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg
    17581 aaacaaggct caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga
    17641 accggcaaat catatttttt tgctaatgta acaactacct cctgattttc atccaaagta
    17701 tgagtatgat gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga
    17761 atctgagcat tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa
    17821 taagataagg atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt
    17881 ttgccacacg tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt
    17941 ttcacagcat gctcgaaacc cggcatattt gccatcaatg tagttgatgt caaaattcct
    18001 cgctgataag catccataat cccataattc acaccatggc tatagccaaa atcatccgaa
    18061 ttaaaaatca cttttcccat ttcattctcc ttcttttttc tactaaaata ggcgcaacca
    18121 aataatcata gtccatttac tatgtgtcat ttggttgcgc ctatagatag ttacgccctt
    18181 attttaatag attcttgcta gatgaattgc caaatagatg atttcatttt cttgaatggc
    18241 aagttgaaat tgctgttcga tgatatcttt aatctttagt gctgtacaat acgctttgct
    18301 atgtttaaat gtttcagtaa aaaaaccaat attttctact ggcgtttctt cctgataaat
    18361 caagcgttta accaggaatt tgatatgaac cattaagcga tgataagtca gtgattcttt
    18421 atcataaacg tttgaatagg atttttctag atgggacaaa atcgtggtcg tcatttctac
    18481 tatttttaag ctctttaaac tattaggctc tcctagctca gcattaatga tatgcatagt
    18541 gatgaatcct acttcatttg accctaactc ggtttgatat cgatgattga ttcgctcgac
    18601 cacttctact gctatatcat attcatttgg ataaaggaat ctcatttctg gcaacataat
    18661 tgctgtgaca tctctatctt ctctttttcg ttgaatagca aaataaatat gatctgtcaa
    18721 tgtaatatag atatttgaat ctaatggaga ggagatccta gctgttatca gttcaatcac
    18781 ttcttccgca aaatccataa attcgattgg aatctgcgag actatctcac tgaatcgttt
    18841 gatcttttct ttagaatcta atacaaataa tttgtcagca tcctcaacat caaatggctt
    18901 actcacttta gcagaaaagc caatcccttt ccccatcgca attttttcta ttccatcgtc
    18961 atcgatcaat acagcattat gattcagctt tttcatcaca tacaccgtta attcacctcc
    19021 tctatatgat aaaacaaaac aacttgcaga ctccttcata catatttttg tctccaaaca
    19081 atttttaaag acaaaaaacg acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa
    19141 tagtagcacc ctacataatt tacaaaaata gtttaacaca taataaaagc gttatcaata
    19201 tcttttttac tcgttttatg ataatacttg tatcgaattg atttggaggt aattacataa
    19261 aaacaaaaaa aatatagcaa ctctctataa gaaagttgct atattgataa ttataccggc
    19321 ggccggggtc gaaccggcac gtcctcaacg gacactggat tttgagtcca gcgcgtctgc
    19381 caattccgcc acgccggcaa atttaaaaat aataactggg gtagctggat tcgaaccaac
    19441 gcatgaggga gtcaaagtcc cttgccttac cgcttggcta taccccaaga ataaagggcg
    19501 aatgatggga atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc
    19561 cacattcgcc atcataaaag atgttattta atttctcaat aaaaaactaa gatgaagaca
    19621 tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc ctcaacgggc actggatttt
    19681 gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt gatttattag tactaaggcg
    19741 gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct ctgccttacc acttggctat
    19801 accgccatta tactattatc aatctataaa ataaagaata aattatagaa actggggtag
    19861 ctggattcga accaacgcat gagggagtca aagtcccttg ccttaccgct tggctatacc
    19921 ccaagaataa aaagggcgaa tgatgggaat cgaacccacg aatgccggag ccacaatccg
    19981 gtgcgttaac cacttcgcca cattcgccat ggcaggggca gcaggaattg aacccacact
    20041 aacggttttg gagaccgctg ttctaccttt aaactatgcc cctataaaat ggaggagagt
    20101 ggattcgaac cactgaaccc taaggaacgg atttacagtc cgtcgcgttt agccacttcg
    20161 ctactcctcc atggtggcgc gggacagaat cgaactgccg acacacggag cttcaatccg
    20221 ttgctctacc aactgagcta ccgcgccata ttttaaaatt attaattgaa taacaagaac
    20281 gacggttccg acgggaatcg aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc
    20341 ctacaccacg gaaccagttc attatggagg ttaacgggat cgaaccgctg accctctgct
    20401 tgtaaggcag atgctctccc agctgagcta aacctccaac attcaattaa aatgacccgt
    20461 acgggattcg aacccgtgtt accgccgtga aagggcggtg tcttaaccgc ttgaccaacg
    20521 ggccaggtaa atttgctacg gagagtaagg gattcgaacc cttgagacag tttggcacca
    20581 tctacatgat ttccaatcat gctccttcgg cctctcggac aactctccag agtgaaagaa
    20641 gctcaatact ctttctcaaa atgagaactc cggcagtagg actcgaacct acgacatcat
    20701 gattaacagt catgcgctac taccaactga gctatgccgg aataacatca gcgtggcgac
    20761 gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc ttaacttctg
    20821 tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt ggtgttatct
    20881 tttattgagt aaattttgtt cactcaaaac tggatttgaa gtcacataag tttttttccg
    20941 agt
//
LOCUS       DASHXG010000046        20626 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.047, whole genome shotgun sequence.
ACCESSION   DASHXG010000046 DASHXG010000000
VERSION     DASHXG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.047"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(18..491)
                     /locus_tag="U2R59_002020"
     CDS             complement(18..491)
                     /locus_tag="U2R59_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8966376.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(596..1459)
                     /locus_tag="U2R59_002021"
     CDS             complement(596..1459)
                     /locus_tag="U2R59_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEM8966377.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1655..3754)
                     /locus_tag="U2R59_002022"
     CDS             complement(1655..3754)
                     /locus_tag="U2R59_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HEM8966378.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3974..5083)
                     /gene="rpoD"
                     /locus_tag="U2R59_002023"
     CDS             complement(3974..5083)
                     /gene="rpoD"
                     /locus_tag="U2R59_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEM8966379.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5107..6948)
                     /locus_tag="U2R59_002024"
     CDS             complement(5107..6948)
                     /locus_tag="U2R59_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEM8966380.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7130..9445)
                     /locus_tag="U2R59_002025"
     CDS             complement(7130..9445)
                     /locus_tag="U2R59_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8966381.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9630..10490)
                     /locus_tag="U2R59_002026"
     CDS             complement(9630..10490)
                     /locus_tag="U2R59_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEM8966382.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10549..11070)
                     /locus_tag="U2R59_002027"
     CDS             complement(10549..11070)
                     /locus_tag="U2R59_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEM8966383.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            11348..12109
                     /locus_tag="U2R59_002028"
     CDS             11348..12109
                     /locus_tag="U2R59_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8966384.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12135..14726
                     /gene="mprF"
                     /locus_tag="U2R59_002029"
     CDS             12135..14726
                     /gene="mprF"
                     /locus_tag="U2R59_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HEM8966385.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14914..16101)
                     /gene="tuf"
                     /locus_tag="U2R59_002030"
     CDS             complement(14914..16101)
                     /gene="tuf"
                     /locus_tag="U2R59_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEM8966386.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16469..16825
                     /locus_tag="U2R59_002031"
     CDS             16469..16825
                     /locus_tag="U2R59_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8966387.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(17066..18070)
                     /locus_tag="U2R59_002032"
     CDS             complement(17066..18070)
                     /locus_tag="U2R59_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEM8966388.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            18236..19087
                     /locus_tag="U2R59_002033"
     CDS             18236..19087
                     /locus_tag="U2R59_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEM8966389.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            19104..19349
                     /locus_tag="U2R59_002034"
     CDS             19104..19349
                     /locus_tag="U2R59_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966390.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            19536..20240
                     /locus_tag="U2R59_002035"
     CDS             19536..20240
                     /locus_tag="U2R59_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966391.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         5845 a         4225 c         3605 g         6951 t
ORIGIN      
        1 aaaagccgtc tagacactca gacggactgg tttctttttt ctttttcata gcattcctga
       61 cagattccat ggaacgttag ccgatgatct tttactaaaa aatgataacg ttcttctact
      121 acttgctcca cttcaagtaa aagatcctct tctacttcct cgatcgtgcc gcagttcaag
      181 catagtaaat gatgatggaa atgtttggcg ccttcttttc tcaaatcata acgggctaat
      241 ccatcattaa aacttacttt atcgacaatt ttcaattctg tcaagatttc aagggttcga
      301 taaacagtag caagtccaat ttccggactc ttttttttca ctaaaaagaa gatttcttct
      361 gcagataaat gctctttctc attttccaaa agcacaagca gagtagcttc tctttgcggt
      421 gtcagcttaa accccgcttc atgtagctgc tgttttgttt ttttcatcgc cgaaatagca
      481 ttcatgacca tttactcaac cccaacaatt tataataatt acaaataaaa aaagatataa
      541 cactatgtta attaaaatta ttataagcta gttaagaaaa acatgcaagg gattctcaat
      601 tagatttttt gactagtttt gtcacaccgt tttcttgtgt aatcaatcct tgtttcaaaa
      661 gattacctaa tgcgcgctta aatgctcctt tgctgatacc aaaagctttc atgatttctt
      721 ctggatccga tttatctgta aagttgattt gctgatctgc agaacgttct aaaatggtta
      781 aaatcatttg tgcatcatct gatatagctt catatgctct tggcttcaat gaaagattca
      841 gtacaccgtc tggtcggaca ccaatcactc gaccttttat ctgctcgcct agacgaggtt
      901 cattatatcg ttcagaagga tggataaacc caagatagaa atcttccgtt aaaacgtacg
      961 tacctgttaa tttcaagcgg tatgctgttc ctatcacatc tttgtttttc atttcttctg
     1021 ttccatattt gcttaaagat ttgaatattt tttcatctgc taaactgccc caaatacggt
     1081 cttttgcatc aactctaagg gaaatcatca agcgatcccc ttttttaggc catagctctg
     1141 tcattgtcgg caattcatca agagatacga caaagtcttt atctggaaga ccgatatcga
     1201 caaacgcacc taaatctttt cgtgtagcag taacgattcc aaaagcgtaa tgaccgatac
     1261 ggcttttagg aatttgtgta gtgatccgat tttcatgttt ttgattttgg taaccgaatc
     1321 cttcaactgc ttcaccgatt ttgtgttcac cttctgattt gcttaagcca aaggtttgtc
     1381 cgtttttttg gacaaagtag tttttttcat tttcatcaat aataatacct gtaaatatag
     1441 ttgctaataa atcgttcatt tttttctccc tctatagtga aaggttttct taatacattt
     1501 ctttgctatc ataacataat gttatctact tgaatagctg agccttggtt tggaaaggtg
     1561 aaaaaaggag tatgacaaca gttgtgtcat actccccttt ttcgaataaa cggtgttaaa
     1621 cggcaggctc acagcctctt tcatttgcct aaaattaatt gctcccattt cctccgaacc
     1681 atccagtttt acagttgatg gttacgatgt aaaatggcaa agcactttct ccaatgcctt
     1741 tcatcaatgc agattttgtt gaagtggcat atagattata atagccttcc ccattttcga
     1801 ttctggcttt ttctaatctg taacctcctt caacgatata tccacgttgg atacatgtag
     1861 caatcacttt gctttggaca cctggtgccc acgtccatgc tggattagat gcatcggcaa
     1921 tatcacttgc tctggcagat ttgattggct gattcgctga gtttgaagag gaaggggtcg
     1981 aggatgccgc ttcttgctgt gctgcttgtg cgaccgcagc ttgttgagcg gcttgagctg
     2041 cagctgctgc ttgagcggct tgttttgctt gttcttcagc tgcttttttc gcttcttctg
     2101 cttttttctt ttcctcttct tcttttttct ctttatcagt gagcatctta tctacttgtt
     2161 tcaattgttc attcaactga gcagatagat ctgtattttt cactttttct actgcttctt
     2221 ttgccgtctt gtattggtcg cgtgttgctg aatccactac ttttccgtct ttaaagacta
     2281 tagctgtttt ttctttagct gtttgcaatt cagcatattg atttttagct tctgtttgtg
     2341 cttgttgaat caattttcca aaatctgtgt tatccgtttc gattgcttgg atctctttat
     2401 ctgctttcaa cttgatgtca tctgctagat gatcatcgac gatggcaggt gctatgaacc
     2461 actcattcac tttttggata tctcggatct tagattggat atcttggtaa gttgtttcta
     2521 actctgaata tcctttttca ttcttaagac tggataaatc attttttagt tttgataaat
     2581 cttgatgaat catatctgca cgaataaatt gatggtgatc atctgtataa aaggcagcaa
     2641 gtttctcatg aagttcttcc atttgttgct gtctttttgc ttctgctgct acttcggctt
     2701 ctactttttg atgatggtca taataagccc agcttcctcc accgagtaga agtactgctg
     2761 ctaaaacgag ataaggtact ttttttgatt ttttcttttg cgctttatct ggatctgttt
     2821 tttctaagtt tgattcttga tgtgtttttt cagtatctgg cacgattgtt attgatttcg
     2881 cttctgcttc aaacagctta ggctggttct cttctttttc tatttttgct tcaagatcag
     2941 taccctcttt gcttacagat tgattttcag catcggattc actatttatt tcatcgggct
     3001 ctgttgactt tttgtctgtg ttttcgagta tttctttttt ctctgcttcc ggcagtttat
     3061 tcgttttttc cttttctaat tgtttttcag taaatacttc agttttttct gtgatatccg
     3121 tttttacgtc ttttattttt actgtttctt tacctgtggc gttttctcta tcagagtctt
     3181 tttcagtttc ttgttccttt tctggctcta ctttgttttc ctgtgcaatt ttttcactga
     3241 tcattttgag cagctctttc gcgtgctctt cttttgtatc ttcacgatgt gctttgatat
     3301 aagcggatag tatcgaattt tcttcctcat tatcgacgat ttctttcagt tcagctactc
     3361 ttcttttttg ttttgattca agcgtttctt cttgattctt tcctgattct tccgaagtct
     3421 catgaacagt tgctttcttc tgttcatttt tctctatatt agttacttga tcgtgagcag
     3481 gtggttcttc gtcttctggt tctgcttttt cgaataattc cattacagat tctagaggta
     3541 aatctttcaa ttccgaccat tcgattggat cgtttaattc tgtatcagga aagactgcat
     3601 cttcagttga tttatcctgc atagctgcat ctgtatttgt ttcttcaatt gattctttta
     3661 tttgctgatc ttctgcagtt atttgatgac cgcagtctgg acagatagta ttctgctcca
     3721 tttttttcga tccgcaattt ggacattttt tcatcactta gcgatcggct cctttactag
     3781 gtttacgcta ccatttaatc tatcatattc tatacgtcac gccaatagct tatttttagg
     3841 atttacttaa aaataatgaa tgaatttcct tcctatagaa aaaaaagctt gagactgcgt
     3901 agtctcaagc tttttttctt ttaaaataaa ccaaacagtt ttactgattt ctcttctggt
     3961 caatagtcca cgcttattct aagaaatctt ttaattgttt tgaacgagaa ggatggcgca
     4021 attttcttaa tgctttagcc tcgatctgac gaatacgttc ccgagtaaca ccaaatactt
     4081 tccctacttc ttccaatgtt ctcgtccggc catcatctaa accaaaacgt aagcgaagga
     4141 cattctcttc ccgatcagtc aatgtatcta gtacatcttc caattgttct tttagtaact
     4201 cataagctgc gtgttctgct ggacttgttg cttcctggtc ttctatgaaa tcacctaagt
     4261 gagagtcatc ttcttcaccg attggcgttt caagggaaac aggttcttgc gcgattttca
     4321 agatttctcg gactttttct gttggaagat ccatttccgc accgatttct tctggcgtag
     4381 gttctcttcc aaggtcttgc agcaattgac gttggatacg tatcaattta ttaattgttt
     4441 caaccatatg aactggaata cggatcgtac gtgcttggtc agcgattgct cgagtgatgg
     4501 cttgacgaat ccaccatgta gcataggttg aaaacttaaa tcctttgcgg tagtcaaatt
     4561 tttcaactgc cttcatcagt cccatgtttc cttcttggat caagtcaagg aactgcatgc
     4621 ctcgtcctac ataacgttta gcgatactta ctactaaacg aaggtttgct tctgccagac
     4681 gctgtttcgc ttcttggtcg ccttcttcga ttttcaatgc taacgctact tcttcttccg
     4741 cagttaaaag ggagacacgg ccaatttctt tcagatacat acgaaccggg tcattgattt
     4801 ttacaccggt tggcgcagaa agatcttctg tttttgcttg ttcagctttt ttctcagcac
     4861 tcttcaagct gtgaattgat ggatcaccat tttcatccac cacactgata cctgcgtctt
     4921 caatcttttg gatcaatttg tccatttcat ctgcattcaa agtgaatggt gtagcaagct
     4981 gattggataa atcatcatat acaacttgtc gtttgggttt gttttctttg atgaaagctg
     5041 ctactgctgc ttcatacgtt tttttatctg ttccatttgc cataaaagaa ggcccccctt
     5101 gagtagctat ttggcttgtt ttaactgttt cgttaaattg atgatttcaa tcgtcaattc
     5161 aagctcaagc tgtttgtttc cagttcgtct ggcttcttgc tgcatttgtt tttttaatgt
     5221 tatttcatca gctaagccag atttgctgat cacatctagc aagtcttgga tttctcgtgg
     5281 cgaactttct tctgccaccg gtaaatattc gatttccacc accaaccgcc ttaaattttc
     5341 atcttgcaaa aagtctaaaa actctgcaag gttgaattca taatgttgtg agacatatgc
     5401 atcgaataaa aaataaactt ctgcatatgc atcatgaata aactgaaatt ctcgttcttt
     5461 taaaatatta cggacagaaa cttctttaaa tgcacgatat aatagaatct gctctgcctt
     5521 ttctacttgc gtcaaaggtc tctttttccg tgcagtttct tgtctcgtaa cctgagtgtg
     5581 ttgactttcc tgaggttctt gacgattttg ctgatttgtc cttcgaagat cgcgcagttg
     5641 tttttgtatc gtctctctgc cgatctgaaa ctctgttgac agttgagata gatacatatc
     5701 ttgttcgatt ggtgaaacaa ctcggctaag ttcaactagt aattcttcga ggtattcgat
     5761 cttgtctttt tcattatcta aatttttccc ttgttttaaa taacgtgatt taaaagtaaa
     5821 gactgtttcg cgcccatgag ccactaattc ttggaaagat gcttctccat acttacggag
     5881 atattcatca ggatcaagct tttctggaac gactacgaca gaaagtgcta atcgactgtt
     5941 ttgccgaagc aattcaatcc ctcgattggt tgcttcaaaa cctgcgttgt ctccgtcata
     6001 gcaaaagacc aattctttcg tcagcttttc catttgttgg atctgttgag ctgttagact
     6061 tgtccccata gaagctaatc cagttttgat accagcctgc catgcagcaa tcacatccat
     6121 aaacccttcg aacaacaaaa tttctccgtt tttccggata tcgcttcttg ctttatcaag
     6181 attaaataaa acttgtcttt tattgaacag ttctgtttct ggactattca agtatttggg
     6241 ctgatctttt tcctgccctt tttcaggtgc aagccagcgt cctgaaaaac cgatcgtctg
     6301 gccttgagaa ttacgaagtg gaaacatcac tctttgataa aaacgatcag acatacggcc
     6361 atcatcatgc gtgacaaaca atccagagcg ttctaacaat tcatttgaaa ttgattcatt
     6421 cttgaatact tgctgaagaa aagaacgctc attaggtgca aaacctatgt tgaattcttc
     6481 aattaattct aaagacaacc cacgactttg caaatattct aaagctggct gtccagcttt
     6541 tgtatgcaat agcatgtgat gatagatttc cgctgctttt tcatgagcag caatcagttt
     6601 ccccgtagca gattcaggat tttggacagc tatagtacgc tgacgccatt gatcttctaa
     6661 cggtatctgt tcgaagtctg ccacttttac cactgcttct ggaaaactta gaccttctag
     6721 ttcttgaaga aaagtaaaca cgtttccgcc tttaccacaa ccaaagcaat gaaaaatctg
     6781 cttgtcttct gcaacagaaa aagacggtgt acgttcttca tgaaaaggac acagccccaa
     6841 gtaattttta ccagactttt tcaactggac atattgtcca atcacctcaa cgatattcgt
     6901 ttgactgcgt actgtttcga taacctcttg aggaatccgt tgagccattt tttcaccccc
     6961 tgctctattg atatcttttg ggtttaacag aagatatttc aggagaataa ccggtaaaaa
     7021 atcgcactaa ctgaaatcag tgcgatttta aaggacacaa ttatacatgt ttgattgtat
     7081 catatttcat tgctttttca agtataacac atttctatct cattaagcat caatttgcta
     7141 ctcttttcag taactgattt tgaatatcag ccttccagta caatactcga agaacaatat
     7201 ttacgagcat gaatacaaag aagtatccta cgctctctcc caaccctaag tttacttcca
     7261 aaattccatg gaacagcatt gcagctacat atatccctac gatcgtcgtt actgctagga
     7321 agatgcgcaa tgggttgaag ggataacaag cttttacaac tgccatgcaa ctgatcccaa
     7381 tcagcaagta atacatcaaa gtagtagttt cagcatttcc ccatgcgaat gtttttccaa
     7441 gtagatacac cgcaatgata ttcactacta caagcaaggc atttggtaaa gcattaataa
     7501 gtgctgtagg caaataacgg taagtgattt ttcttttatc ttgttcaaaa gataaaaaga
     7561 aggaaggata cccttcaatc gctaaatcaa tcagcgtgat ttggataggg ataaacggaa
     7621 atccaattgc tgtaacggca catataatcg ataaaataaa tgaataaatc gttttgataa
     7681 aaaagatgcc tgagactttc gtcacattgt tgaccactcg gcgtccttca aacaggactt
     7741 ctggcaatgt agtaaaatca gagtccaaca ataccagatt cgcaatctga cgtgttgctc
     7801 catcaccttc tgccatagca atgctgcaat ctgcttctct taacgccaaa acatcattca
     7861 caccgtcgcc tgtcattgca accgttctgc cgctttcttt caattcattt accagcaatt
     7921 tcttttgctg cggactcact cgtccaaaaa ccgtatagcg atgagcagct tctcgcactt
     7981 ccatttcttc agtaatttga gaaagatcga catacgcatc ataattcggt aatcctgcac
     8041 gtctagcgat attggagaca gtaaaaggat tgtctccaga aatcactttc agatccacac
     8101 cttcctcatg aagataagct agtgtttctt gagcgttttt tcggattgga tcatcgattt
     8161 caaacagagc aaccggctca acaaatgctg gtttttcttc gttcaattgc tgatttggag
     8221 cgatccccaa cataagtacg cgatagccat tcgcttgggc tgtttttaga ctgtccggaa
     8281 gccgatcttc ttccaccaaa cgttcaggcg ctcctacgta cacgactccc agttctggaa
     8341 attccatcgc gccccatttg cgatcagaag aaaatgcgac tttgtttgtc acatcatacc
     8401 gattagaaag ctcaaaataa tctctcatag cccgcatagt gatgttgtta tcactgcttt
     8461 ctgccagata cgtccccata atttctggga tggctttctc gtacagcgga tgtagtgctt
     8521 ctacccgctg gatactcatt ttcccttcag taatggtccc tgttttatcc aagcataatg
     8581 tatcgacatg ggccagcgtt tcaattgaat acatgtcttg aacaaggatt cgtttttttg
     8641 ccagtttggt tacccctgtc gttaatgcaa tacttattag caataccaaa ccctttggaa
     8701 gcatgcctaa caaagctgct gcagatgcaa taacagaaat tttgatagaa gcatcgcgga
     8761 tgaacagtgc ttccaaaaat agtatgatcc ccaaaggaat aatcacgaaa ctagtgaatt
     8821 tggatacttt gcgaatcgaa tctacaagtt cagaacgaat agctttgtga gtctttgcct
     8881 cgctagtcaa gcggacagca taattatctg cacctactcg gataacttca gccatgacag
     8941 aaccgcttgt caaaaagctt ccagaaagca attcagctcc agtttctttg acaatcaaat
     9001 cagattcgcc tgtcaaaaga gcttcatttg cttctgcccg tccagatata acctgtaaat
     9061 cggctggtat ctgttctcct gctccgattt ttaccaaatc tcctaatacc agctctttag
     9121 tagaaatcga ttgttcttta ccgtcccgga tcactagtac ttctgattgg gaaacaatcg
     9181 ataatttccg tacaagattt cttgcatgta tttcttgata aattccaata acgatattga
     9241 cgacaataat tgctaaatac gccatgttgg aatacgcacc tacaaataac agacaaatcc
     9301 caataccaaa gttcagaaaa ttgaataacg tcaatatatt atcgctgaat atttgttttg
     9361 tactttttga tgcatcttcc tggtagtcat tttgctggcc agaagccatt ttctgaacta
     9421 cctcttgctg tgtaagtcca ttcattttct ttttctccat tttccgccaa ctttcaaaaa
     9481 taatcacgtg tttaagtcta gcgtgttcca agattaaaaa caacttgttt ttataaaatt
     9541 tatagaaaaa cacacgaatg attttacaaa aaagatgcca acctttttgt ttgaatcacc
     9601 cgtgtgctgt ttttattatc aatctatctt tacttatatt gttcctccaa acggctcatc
     9661 caccaaccta gtgctgtacc ggctataaaa agaacaggac aagctagtac cccagcaact
     9721 cccaatcccg cgtaatcggt aggaatgatc ataatcgttg aagcaaaaac tacacctaaa
     9781 atgaaatgga atagcttgct atatgccttt gagaaaatgt aatccatgat ttttgacaat
     9841 ccaagaacac aaagaatccc accaattccg atcggcacaa tcacttcaag tcgtacttct
     9901 ttaaatccgt cagccatcgc tttatacaat cccatataca ccaaaaaatt agaagggctc
     9961 aatcctggga cgatcatacc caaaccaatc aatccgccgg caatcagcca tgttccaaaa
    10021 ttctgatcga cttgcccgtc aaataattga gcgccgtata ataaaaacaa ataagccaga
    10081 acaaaagtaa caaccatgat gatcacatca gaagtatctc ttcctttttt ccctgcttct
    10141 ttccataacg caggaacagt tccagcgata catccgacaa aaaaccataa tatcgttgtt
    10201 tcatacgcac ctaataaaaa actgactaaa aaagaaagta gaaagatgcc tgtcactccg
    10261 cctagaccaa caggcagaaa aaacaaaaca ttttctttga aattttttgt aaggtgggct
    10321 aaaaaagaaa tcagccgctc atacatgcca aagacagctg ctaatgcacc accgctgact
    10381 cctggcaaga taaatcctga accgataaac attcccttca caaaccgtaa catccagtct
    10441 ttggttgtgt accccacttc ttgattttcc attttttgcc ttttttccac tatttgcgta
    10501 ctccttcttt catttaattt tattcatgat tgaacatttc ctgctatttt acttaaagac
    10561 tttttcatag gtctctatta ttttttcatt cattttgaca atatcaggat aaaacatgtt
    10621 acctccatta tgatagagat agccgccatt gtaaagcaag gactggatcc gccaatatcg
    10681 gtattgtttc ccttcctcat ttcctaaaag tgggctcagc acatctttag aatacgcttc
    10741 tgctaattct actgtgtttt ctccgccatg attttttaca taggcaatat aatctttccc
    10801 aaaattatat gcttggacag ctgtccataa atcgcatcct tgtttctttg cttctactat
    10861 catttccgcc aaatatttga caccttgatc aatactgtca gctggattat caatgatctc
    10921 agcttctcca tgcagacttt ccgagctctg catgagatct gtcccttttc cttttgattc
    10981 ggtcaatatt atcgccttga tcaaattctc gtagttttcc atatgataat tttttgcagc
    11041 tgttgttatt tctatttgat agctttccac tcgttttacc gaacgataag ttcttcctca
    11101 taaaaacaac accgcaccaa taaccgtcag aatgatcatg taaaaaagaa tacggataat
    11161 agataatcgt tttcgcttca tttcatcacc tagttatttt gacatctttt tttatcttac
    11221 tatttcttta tcttcttggc tatttcttcc ttgatttctg tgtacgcctt aagaaaaaat
    11281 gaattttcct gtattttttg acatcttacg aaaatgatcg ttgtttttca gtaaaaacaa
    11341 ttgcccaatg actgatataa tcgttatact ttacacagta ggtgattatg tgaaaaaaga
    11401 aaagaaatat gcaaaaatgc cagatgggag cgaaatttac tatgaaaaga gcggtcaagg
    11461 cttccctctc tttttactgc atggcaatga cggcagcggc cgcttttttt cagaacaggt
    11521 ccctgtactc gaacgctact ataccgtgta tctagtagat agccgaggac atggtcgttc
    11581 gacaaacgaa gcatctatgt tgaattttca gttaatggcc gaggatctga atacgatcat
    11641 gttgctggaa aaaatcgatc aggcagattt tcttggattt agtgatggag caaatctagc
    11701 actggtattt gccagcagct tccctaaaaa agttcatcga ttgattttaa attctggaaa
    11761 cacgcttgtt aaaggcgttc gtttttctgc cagagtcatc agtaatattc attatgcatg
    11821 ggtatggtta ctctctttat ttcgcccaag tcttcgcaaa aatcttttag ttatcaaact
    11881 tttgctgcat gacatcgggc ttacagaaaa tgatttaaaa aaaatcaact cccccacttt
    11941 gatcatcgtg ggaaaaaaag atgtaatcaa gctaaaacat tctttgtata tagctaaaac
    12001 tataccaaaa gcttcctttg tgcttgtgaa agaacaagga catgaattag ctagaaaaga
    12061 tcctgaacgc ttcaatcgag aagttcttca atttctttct gaaacataac tattaggaat
    12121 agaaggtgat ttatttgtta aaaaatacca tacaatggct gaaaaaccac ctaggactgt
    12181 tcaaaacaat ctttttgatt tctgtcattg tcattattgt cggtgaattg atgtccatcg
    12241 gtaaaactct atctatccag caattaggag aaacgtttgc cactatacct gtatggaaaa
    12301 gcggactaat gctattgatt ggtcttatct ctgtgttacc tatggttggt tatgatatta
    12361 ttttgaatcg gatgcttgaa caaaagcaga atcctcgtta cctgtttgag acaagctggc
    12421 tgatcaatac gatcaacaat attgccggtt tcggcgggtt tgttagtgtg gggcttcgct
    12481 ctgaactata tggacaaaag aaagagagca gaaacgtgat ccaagcatta tcgaaagttt
    12541 tcttgttttt gatggctgga ctttctattt acagtctgct ttctttttta cttgtagtct
    12601 tcacgccagt tgctcctttt ttgaagcaat attggatatg gttgatcggc ggcggtctat
    12661 attttcctgt cgtcttttta tttactactt tcaaaaagaa aggattcctt ggtggtacct
    12721 cacttaaaac tcaaggacag ctattgctag tttcattgtt ggaatggacc ggtgtcctgt
    12781 ttagtttcct ttctgttggt tatttaatgg aaatccggat tgatctgtgg caaacaattc
    12841 cattattcat tgctgcttca gtgataggaa tcgtgtctat gattccagga gaaattggga
    12901 gtttcgatgt aatgatgatt atcgggttgt ccgctattgg tgtgccaaga gaaatagtcg
    12961 ttgtgtggat cttgctctat cgcctgttct actacatcat tccgtttttg attggaatcg
    13021 tctttttctt caaaaatatc ggttccactt ttgatcagcg ttattctggt atccctaaac
    13081 aattagcaac agaaattgcg cataaaatcg tggttgtctt attatacttt tctggaatca
    13141 tgctagtact ttctgccact atcccgcaag cttttacaga gtttcgctgg cttcatagtt
    13201 tgaacccatt gaaatttcat tttattatcc aatttcctag tatactattg ggatttcttt
    13261 taatcattat gggcagaggg atcgcagcac gtgtgaaacg agcatatttg cctacaatct
    13321 tcttgattgt tctagcttta ctttatgttt tattaagtga ttttagtttc acaccggtgg
    13381 ttttcttgtc tattctgctt ctgatcattc ttgcttctaa aaacgaatta tttcgggaac
    13441 aattgatcta ttcatgggag tggcgtacga tcgatggaat cattattggt gcactgtcct
    13501 tgctttacat cgttattggg gtatacaatc tgccggattt ccctcatcgg cgtcaccatt
    13561 ttatttcctt tttcttattt ccttctgaaa agatttggtt ttcgggattg ttggccatca
    13621 tcgctgttag tttcatgatc gttctatttg ttcatttcct tcaaggagaa aagaaacaga
    13681 ttggcgaagc ctttaatgaa gaaaaggccc tgaagatcct tacaacttat ggaggaaact
    13741 ccgatagtca attgatcttc ttaaaagata agcggatgtt tgcctatgaa aaagacggtg
    13801 aaccaactgt tcttctccaa ttcgcttgct tcaataataa atgtattgta atgggtgatc
    13861 cttctggtaa gaaagaagat tttccagaag caatcgaagc ttttatcgaa gaaacagatc
    13921 gactatgcta tttaccagtt ttctacgaaa caagcgaaga gattgttatg attttgcatg
    13981 aattcggcta cgatttcatt aagatggggg aagaagctta tgtagacctg aatagtttta
    14041 caacttcagg gaaaaaaatg aagggcactc gtgctgtctt gaatcggatc gaacgagaag
    14101 gatttacatt tgatgtctta caaccaccat tttctactga gcaaatgagt actttcaaaa
    14161 atatctctga taattggttg ggttcacgaa aggaaaaagg gttttcttta ggctttttct
    14221 ctgaagatta tctacaaaga gcgcctattg cagttgtcaa aaatacccaa gaagaaattg
    14281 tcgcttttgc aacgatcatg cctacttaca cgaacaataa agtaggaacg attgatctga
    14341 tgcgatatga ttctaaaaaa gcaccttctg gcagtatgga tttcttgttc ttgcatttgt
    14401 ttgcctatat gaaagaagaa catatccaat ggttcaattt agggatggcc cctctttcaa
    14461 atgtcggaac ttccagaaag agttttttac aggaaaggat tgcatacttg gtttacgagt
    14521 ttggttctca tttttattct ttccatggat taagagaata taaaagcaag tacgctacaa
    14581 actgggtctc acgttatact ctatattcta gagatagttg gattgcatat gttatgattg
    14641 ctttgctgat tattgataat gcgccagttg agcagacaca aggtagaata agtggtttga
    14701 aaaaatggat acgaagaaag tattaaaaac tgcataccga tagatgaaca ctctcatgat
    14761 gaataaaaga gactgaagta aaacgaaagt tcatgcttct acaatctctt cttatacaat
    14821 tgaagaacaa agagcggtcc aaacagaaat cctgtttgga ccgctctttt attttaaaca
    14881 tttttcatta ccaaaatatt cgagtcgcgt ttcttatgct tcgatctctg taacgatacc
    14941 tgaacctact gtccgtccgc cttcacgaat tgagaatgtc gttccgtttt caacagcgat
    15001 tggatggatc aagtcaacat caatcgtcac gttgtcacca ggcatgacca tttctgtatc
    15061 ttctggcaat gtgattgttc ctgtaacatc agttgtgcgg aagtagaact gtggacgata
    15121 gttgttgaag aatggagtat gacgtccacc ttcttctttt gtcaacacgt acacttctgc
    15181 tttgaatttt gtatgtggag taatggaacc tggtttagca agtacttgtc cacgttcgat
    15241 atcgtcacgt tggatccccc gtaacaacac gcctacgtta tccccagctt ccccgtaatc
    15301 taacgtttta cggaacattt ctacacctgt tacaactgct ttttgtgttt caggtttgat
    15361 ccctacgatc tctacctcat caccgacacg aacagcacca cgatcaatac gacctgaggc
    15421 aacagttcct cgacctgtaa ttgagaagac gtcttccact ggcaatagta atggtttatc
    15481 tgtatcacgt tctggtgttg ggatatattc atctactgta tccatcaatt ccataatagc
    15541 agcttcagca tctggatcgc cttgcaatgc ttttaatgcg gaacctttga tcacaggagt
    15601 gtcatcgcct gggaaaccat attcgctcaa taactcgcga acttccattt ctaccaaatc
    15661 gatcaattct tcatcatcga ctaaatcaac tttgttcaag aaaacaatca ggtattttac
    15721 accaacttgg cgtgacaata aaatgtgttc acgtgtttga ggcatcggac cgtcagttgc
    15781 agaaacaact aagattgcac catccatttg tgctgcccct gtaatcatgt ttttcacata
    15841 gtccgcgtgt cctggtgcat caatatgcgc gtagtggcgt ttttctgttt catattctac
    15901 gtgtgcggta ttgatcgtaa tcccacgttc acgttcttct ggagctgcat caatactagc
    15961 atagtcttga ggatttgcta ggcctttttt gcctaatact gtagtgatcg cagcagttaa
    16021 agtagttttc ccatggtcaa cgtgtccaat cgtaccaatg ttaacgtgtg gtttacttct
    16081 gtcataatgt tcttttgcca taatttacaa acctcctaaa taatatagat cactgaaaaa
    16141 tttcagctct caccttttta ttatagtctt tttttgacta aatcaaaaag aatacgtccg
    16201 acttactttt tgtaagattc gaactaagct tattatacgt caatattggt caaagtcaac
    16261 taagagcact cgtctgtctt atacgcgaaa aaagtacctt ttataaataa aaaaatgtgt
    16321 tttttgagaa aaacttcaag atagtcctta actttctttt gaagcaataa gaacaaaatg
    16381 aggaaaagtt taaaattcag ctgttgccaa caactttcaa tagacgaaat cttctatttc
    16441 gttaataata aggaaagagg tgaagtacat gaaaaaatta attggcgtac ttgtcgtttt
    16501 aggcatattt ctcggcggaa gttttgcagc ttatcattat ttttacggcg gcgaagctta
    16561 ttatacaaaa atcacgacga atggcgaaat gtcagctacc caagcagata acggagagaa
    16621 attcacgact tatacctaca agcaagcggc ttataataaa gatggtgaaa aaaaacaggt
    16681 gacgcttcgc gaagaaagag aacatccatt aaagatgaat gcgtatctta aactcaaagt
    16741 caatcctcgt aaaggtgtat taagctggga agaaataaag gcttctgaag tgcctaaaaa
    16801 tgcggcagaa aaaatcgata attagtaaat ggtcttaaaa ttttattaga taaaaagagg
    16861 ctgggacaga agcgtttaac tccaagaaat aagaaggagt tgcttctgct tccgccgttt
    16921 atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtctcacgc tctttttttg
    16981 ttatattcgt cttttccgat ccttctcttg acacaattca tttaactgat cactggtact
    17041 tgaacaccta atattctagt catttttata aacgattcaa tacttcatcc acatttttga
    17101 tcatcacgga tatcgtacca tccggattat tcacaaattc aatcaaatct gggttgcgat
    17161 atacatctac tggtacgatc agttcgatcc cgtttgatag cttgaatttt tgttttccaa
    17221 attttttctc agaaatttct tgtacttctt ttacaggagg tgcttctggg acaaatcctt
    17281 gctcttgtac ttcttcttta aaagccattt ttgccgtgat gttttccttg aagacttttt
    17341 ccgcaatcat ctcatgatcc aaccgacctt tttcttctat cgtatcatag acagcttctt
    17401 tcaaatcagc catgatatca aattcttctg tctcaaattt ttttccaaga tgcttggcta
    17461 ctttttggat cacttttaca ttttcttcta aagaaggtgc aggaacactt tcgatcactc
    17521 ttccagaaaa ataaagctct tttttgccag aaaactcata ttttttttca attaattcgt
    17581 aggtccaatc agtcaaattc acagcgaatg cttcatctgc tttttgtgtt ttcgccccta
    17641 gaattgctcg attcaaaatc aagcggttgt cgatccctgc ttcgtctgct tcaacaaagt
    17701 gagtgtaagc ctcacgataa ttgactttca ataaagataa gtacatcact gtatctaatt
    17761 catacaagac aacaaataca tctgcactag gtgcttcttc actttcttgg tagatatcga
    17821 accaccgctg aacgattgct tcacttgctt ccacaaaatt ttcttgagcg attttaagtg
    17881 attcaacgat catgctttct tctgctagtt gtccagtttt tgtttgagca gaagagattt
    17941 tttggatctt cttttgaaga aaatcacgaa tatattcttt tgtcagatcc agctcttttt
    18001 gtgaaaagac tggagaacca gtttctctgt caataatatg cagaattgct ttttttaaat
    18061 agatatccat tttctcattc ccttctgtct tagtttacgg aaaaaaaatc aaaaatacca
    18121 gaatcaaaat cattttcttt taaacaaaaa tttcaagagt agaaacaaaa tggattcttt
    18181 ttttcgaaaa atgcgctaca cttatagttg aacgaataaa aaaggagctg aaagtatgaa
    18241 ttcattaaca agcacttatc gtctatcaaa tggttacgaa atcccggtag taggattcgg
    18301 cacatggcaa acacctgatg gggatgtcgc tgtttcctct gttaaagaag cgctggctgc
    18361 aggttatcgc catatcgata ctgcccaagg atacaagaat gaagaaagcg tcggccaagc
    18421 gattaaggaa agtggaattc ctagagaaga gatattcttg acaacaaaat tatggaatgc
    18481 aaaccacagc tatgaacttg tgatgtcttc ttttgaagaa tcattgaaga agctccaaac
    18541 agattattta gatctgtttt tgatccactg gccaaaccct gttgcttttc gtgataattg
    18601 ggaacaagca aatgcagata catggcgagc atttgaagaa ctgtatgaag caggtaaaat
    18661 caaagcaatc ggtgtgagca atttcttacc ccaccatcta gatacactag caaaaacagc
    18721 aaaaattatg ccgatggtca atcaagtttt ccttgcacca ggcgaattac agacaactgt
    18781 agttgagtat gcaaaaaaac atgatatgat cctcgaagca tatagtccat taggcactgg
    18841 taaaatcttc gatgtgcctg aaatgaaaca aatcgctgaa gcacatgaca agacgattgc
    18901 acaagttgct ttgcgttggt cgctgcaaca cgaattcctt cctcttccta agtcagtgac
    18961 accaagcaga atcaaagaaa atactgaatt atttgatttt gaattaacag aagaagaaat
    19021 gaaacaaatc gatcagttag atggtgtagt cggcaaagca aaagacccag atactaccca
    19081 attttaagtc gaaaggtgat tttatggatc caatcgaacg cttgaattct ctctcggaag
    19141 aagttaccca gacttttcat tccgattttg tctttttgat cgatgcagag aaaatccaac
    19201 attttcctgc aagaaactgg acacatgatc aaatcatcga agaactgaaa aaacggttcg
    19261 atcattcgct aatggtcaaa ccctggcacg aacatgaagt catttattca cctgaactac
    19321 ctgtttttgc cttgataccg aaaaaataga aagaatggaa cggattatgt atatatacat
    19381 aatccgttcc attttttatt tttctttcaa aaaacgggaa aatacgcaaa tttttctgtt
    19441 gtaatttgcg tatacgcaag tttttttgca ttactccttt tcatttggct gtttttttct
    19501 tataatcgaa agggtatgag cgaaggagag aacatatgaa gaaaaaacag aaacaaaaat
    19561 tattaaatca attccgtcct tcattggatg gtgtaagagg acaattattc cgttctctag
    19621 aagaagagag cttgcgacgt tatggtttgc cgttacaagt catgcttgat cccaaaaacc
    19681 gtcaaatctt aacgatcgga ttagctggga aaacaaatga agatacacgg atcaacgtgc
    19741 caatcgatga caacttcaat actgtattaa agagaattcg ttcaggagaa aacgggattt
    19801 tcgaacgatt ccgtgacaat cttcttattg aaatcgtgtc ttactggaat gatcaacgat
    19861 tgaaaaacga tgaaccaact gcgcaagctg ttgcgacacc agttacagaa gaaacagtca
    19921 gtgtgccaga agaaaaaacg gaaaaaccaa aagcggacac aactgaaaat acacgctcaa
    19981 ctgatacgaa tgccgcttta agttttgctg atttttcaaa agccgttgct gagtatccta
    20041 aattttacac agaacaaaat gaacatgaag tagttattaa tgaaaaaaat gctgatgaac
    20101 ctcgtaaatt agcaactatt tctatgacta ctgaaaatga gttcgttatc gaaaaagcac
    20161 tcgaacggaa atacaaagtc aaattgactt tgattccttt gatcgaacaa tttgcagcga
    20221 cagcgattac tgatcgataa aaattctatt tgtcataaaa ggctgggatt taaaatccca
    20281 gcctttttag tcatataata atttctacag caagtaaaaa gaaattcctt ctaacatcag
    20341 gctcaaatat cagcttgacc tgtccaacaa atcacctatg atcctacaat gttaggcgac
    20401 ttctcttcta cctgaagata tcttggagtt gcctgatttc ttaagatgcc taaccttaac
    20461 tataaaaaat tctaataata aacatatttt ctgatagaga aaaaagcggt tctataatat
    20521 tttgtgttgg tggaaaatcg aaagcgattt tctactaaca cttttttctt cgtttcaact
    20581 caaaaagaga ctcacttttg gtaaaattta gtcgaccaaa acgtca
//
LOCUS       DASHXG010000047        20295 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.048, whole genome shotgun sequence.
ACCESSION   DASHXG010000047 DASHXG010000000
VERSION     DASHXG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.048"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            637..867
                     /locus_tag="U2R59_002036"
     CDS             637..867
                     /locus_tag="U2R59_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966392.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            1026..1859
                     /locus_tag="U2R59_002037"
     CDS             1026..1859
                     /locus_tag="U2R59_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HEM8966393.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            1852..3267
                     /locus_tag="U2R59_002038"
     CDS             1852..3267
                     /locus_tag="U2R59_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEM8966394.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            3279..4808
                     /locus_tag="U2R59_002039"
     CDS             3279..4808
                     /locus_tag="U2R59_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8966395.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            4726..5778
                     /locus_tag="U2R59_002040"
     CDS             4726..5778
                     /locus_tag="U2R59_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEM8966396.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            5780..6097
                     /locus_tag="U2R59_002041"
     CDS             5780..6097
                     /locus_tag="U2R59_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966397.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            6224..6847
                     /locus_tag="U2R59_002042"
     CDS             6224..6847
                     /locus_tag="U2R59_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEM8966398.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            6862..7752
                     /locus_tag="U2R59_002043"
     CDS             6862..7752
                     /locus_tag="U2R59_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HEM8966399.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            7775..7990
                     /locus_tag="U2R59_002044"
     CDS             7775..7990
                     /locus_tag="U2R59_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966400.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            8002..8343
                     /locus_tag="U2R59_002045"
     CDS             8002..8343
                     /locus_tag="U2R59_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966401.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            8343..8714
                     /locus_tag="U2R59_002046"
     CDS             8343..8714
                     /locus_tag="U2R59_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966402.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            8707..9102
                     /locus_tag="U2R59_002047"
     CDS             8707..9102
                     /locus_tag="U2R59_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEM8966403.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            9104..9481
                     /locus_tag="U2R59_002048"
     CDS             9104..9481
                     /locus_tag="U2R59_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966404.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            9482..10090
                     /locus_tag="U2R59_002049"
     CDS             9482..10090
                     /locus_tag="U2R59_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966405.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            10090..10431
                     /locus_tag="U2R59_002050"
     CDS             10090..10431
                     /locus_tag="U2R59_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966406.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            10673..13462
                     /locus_tag="U2R59_002051"
     CDS             10673..13462
                     /locus_tag="U2R59_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEM8966407.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            13452..14192
                     /locus_tag="U2R59_002052"
     CDS             13452..14192
                     /locus_tag="U2R59_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966408.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            14189..16951
                     /locus_tag="U2R59_002053"
     CDS             14189..16951
                     /locus_tag="U2R59_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966409.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            16964..17872
                     /locus_tag="U2R59_002054"
     CDS             16964..17872
                     /locus_tag="U2R59_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HEM8966410.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            17872..18492
                     /locus_tag="U2R59_002055"
     CDS             17872..18492
                     /locus_tag="U2R59_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966411.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            18496..18945
                     /locus_tag="U2R59_002056"
     CDS             18496..18945
                     /locus_tag="U2R59_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966412.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            18945..19439
                     /locus_tag="U2R59_002057"
     CDS             18945..19439
                     /locus_tag="U2R59_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966413.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            19453..19884
                     /locus_tag="U2R59_002058"
     CDS             19453..19884
                     /locus_tag="U2R59_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966414.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            19886..20023
                     /locus_tag="U2R59_002059"
     CDS             19886..20023
                     /locus_tag="U2R59_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8966415.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            20061..>20295
                     /locus_tag="U2R59_002060"
     CDS             20061..>20295
                     /locus_tag="U2R59_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966416.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHT"
BASE COUNT         7350 a         2792 c         4198 g         5955 t
ORIGIN      
        1 attaggaaac aggatcgaca aaataaaatg taagggagga aatctccctc atcgtttaat
       61 taagcttcga taggcagcaa cggaaatatt aagaataagg atgtgaattt caactccttc
      121 taaattgttc ttattatcta tcatccgttg ctgtctattg tttttttaat tattcacacg
      181 ataactaaag gtaagtgaag agaaatgatt ccattaataa tttcaatttt tgcgctttgt
      241 cttaatgtat atatgattgg atttaaaaat gggcaaaata aaaaatagta gcagccaaga
      301 ataattttat agtgtcactg tggcggaaag ggtagacgct aagcatgtgt gctaggtcaa
      361 tgcttcggca accatgcaag gttcgattcc ttgccagtga ctttggcaac cgaggcatcg
      421 gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg tgtaggttgc
      481 tattacataa ctggttaggt tagattgaga tttgggattc ggtacaaatg aatcgtcaaa
      541 tgtctcaagc acaggatcgg aaacgtccct gcctgtgcat tacatattag atcactcttt
      601 gagtggtctt tttctttaca taaaggaggc tacataatga gaaactactg gtatgtatcg
      661 ctaactaatg aatatcctcg aaccattgat gattgttcag tgcgtgttgt gcgttctgta
      721 caaatcaaag ggaagtactc tattgtcgaa atggggagag aagcagaacc atgtgagatt
      781 gatgcgtgca agctcgttta ttgcggtcat ggtttctatg atgaaccaaa cattcaaaat
      841 aatattaaca agaatttgag ggattagaat gcaagaaatg gcttaaaaat ctccaatcag
      901 gacaaatcaa gttagacaaa gtttccgatt taaagatatt gattgaagct gatttaatgc
      961 taaaagatat tgaaaattag aaaacaaaac tcaacctaaa cagaatgtga ggtggtgtgt
     1021 attgaatggc aagacaacgt gatccaagac gtgatgaagc caaaagaatt tggttagaat
     1081 ccaacggaga aaagcagtta aaggaaattg catctgaatt aaatgtttca gattctcagg
     1141 ttagaaaatg gaaatcgcaa gacaaatgga gcgctgaatt gattagtaac gttaccaatg
     1201 gcaaaagtaa cgttactaat caaggtggcg ctcctattgg taatcaaaat gctaaaggta
     1261 acaaaggaaa tagccgagct tctccgccag tgggtaataa aaacgctttg aaaacaggtg
     1321 agtatgaaac aatatttttt gacacgttaa ccgataatga gaaggacatc tattctagtt
     1381 tgaatgatga tccttctttt gctttgtccg aagaaatacg acttcttaaa ataagacaac
     1441 ttcgaatgat gaaaagaatc caacaagctg aagctggact aaatgatgaa gaagtcgaac
     1501 gattgcagca gctaagaaag attaaaactc cgattgaaaa aaatggtaaa aagctagaaa
     1561 tcaagcgtga ggttatgcaa gatgtgcaga ttagcagaaa aaaacatcgc aaaattgatg
     1621 atattctttc aattgaagat tcattgactc ggattagcaa ccagttagct aaagccatca
     1681 agcaaatgaa tgaactttat atgaatgaat acagaactga tttaattaaa gctcagactg
     1741 ataagatcca agctgagaca aatgaaattg gcggaaataa ttcaggtgaa gaaatagaag
     1801 aatggaaaca ggcagtttta aatgccgcaa acaaacgggc ggtgaaagaa aatgaataat
     1861 gaatttattc cttttgctga tattggttct gccattgatt attactatga taaaccagta
     1921 gctttttgcc aagatatttt gcatttgaat cctgatgaat ggcaagaaaa tgttttaaat
     1981 gatttagctg aattttcaaa ggtttctgtt cgttctggtc aaggagttgg aaaaacagca
     2041 ttagaagcag gagcaatact ttggttctta acgtgtcgac cctacgctaa agtaatagca
     2101 acagctccga caatgaagca actttacgat gtactttggg cagaggtagc taaatggtta
     2161 aatgatagct tgatcaaaaa cttactgaag tggacaaaga ccaaaattta tatggttggt
     2221 gattcagagc gttggtttgc tacggctaga acagcgacta aaccagaaag tatgcaaggt
     2281 tttcacgagg accatatgtt gattgtggta gatgaagctt ctggtgtgtc tgatccaatt
     2341 atggaagcta ttcttggtac gctatcaggt tttgataata agctgttgat gtgtggaaac
     2401 cccaataata ttgaaggtgt cttttatgat tcccataatt cagaccgtga taaatacaga
     2461 gttcataaag tatcaagcta tgatagtaaa cgtacaaaca aagacaatat agaaatgatt
     2521 cttaaaaaat atggaaaaga aagtgatgtt gctcgtgtcc gtatttttgg agaatttccg
     2581 aaaggtgcgt tggattcatt tatcagtctt gaaacagttg aattggctac agaaaaacaa
     2641 attagtgatt ctttagtcaa taaaacaaag gttgctcata ttggtgtcga cgtagctcga
     2701 tatggtgatg attctacgat tctctttcct agaattgcta ccagggcatt ggagtatgag
     2761 aagtattcaa aacgtagcac catggaaaca acaggatatg tcatcaacat ggccaagaat
     2821 ctaatgagtc aatatccgag tattgataaa gtgatgatta aagtcgatga cactggtgtc
     2881 ggaggtggtg taaccgaccg cctagaagaa cttatagaag acaaacatta tccttttgag
     2941 gtgtttggag tgaataacgg ttcaacatca gaagacgatt tttacgataa tttaggtact
     3001 caactatggg gaaacatcaa ggaaatgtta gaagaaaata tgacagcaaa tcttaacgga
     3061 gaacagcctg ttattgaatt gccttctgat agttcgttaa tcaaagaatt aagtactcgc
     3121 aaattcaaaa tgacaagtag aagtcgtata cgtttagaaa gtaaagatga tatgaaaaag
     3181 cgaaatattg gtagtcccga tattgctgac gcactggctt tagcgtttta tgagccacca
     3241 agtcactatc aatttattca attttaggag gtgagctttt gattagtaca gtattatctt
     3301 tagagagata taagaagcta cgtgttaaat atgcaacaca aattgaagat ggaatgtttg
     3361 atccgaatgg ttttatagaa gatatgaaac cattttttgc tgatcgcgaa agaaaatatc
     3421 tagcttatac tagcgaaaag aatgaaatag ataatagacc aaagcctaac actgatattg
     3481 taaaagttaa taataaactt catgctggta tgtattcaat tgtcgtagac caagcagtca
     3541 atcattttac tggtatacct atcaaatggg attacgatgt atcggaacaa aaaagaacac
     3601 tcattcaaag attaaaagat aaattcttaa aaaatgatat agaacttccg acagttccag
     3661 aagcttttaa caaattaaca agcaatcttg attccatgag attcgcaatg cttgattctg
     3721 aaactgcaac ttttcaagga gcttgtggag tagctttccg attgctagag cctgtggaag
     3781 aagatgatgg ttggaagtta agagcaagta atattgaacc ttggagagca gaaagatatg
     3841 gaaatgccgg aatctatatc aaagaaaagt atgactctta ccagaaaaaa ttttttcaag
     3901 aaatgaaagt tatgacaaga aataaaattc tgacatatgc ttgctatggt gatttgaatt
     3961 ttgttacaag cggaacgttc aaaaaaattg atgagaccga taaccctttg gggacgatta
     4021 ccttggcaga atttaaaaat aatacgaatc gttattgtga ttttgaagta gctgaggaaa
     4081 ttggagatgc aattgatcgt gctttgtctg atcaacaaaa cgaaatcgaa caatttaagc
     4141 ttgcgtacat gcttgttact ggcacaacaa tgagcaaagg cactgctaaa gaaatgatga
     4201 atcagctagg gattatcaac ttaaaagccc ctactgcaaa agctgaatat gtcacaaaaa
     4261 atttagcaaa agatttcaat gaatatcata tggatctatt gaaaaaacag ttttacacca
     4321 tttgtaaagc aatcgatttt aacgatgagg tgtttaaatc aaacagttct ggagaagctc
     4381 gcaagtggca aatcattagc ctagaagcga aaacaaatac taaagagcaa tattttagag
     4441 aaggattgaa agaatgcgca gaaacaattg ctgcttttct taagtttcat gacaaagtag
     4501 aaattgagcc tgaaaaaatt atttttactt tctctagatc tttgccaact gatttaagtt
     4561 atttagctga agctttacct aaacttgcac catacgtatc caaacgaact attcagagcc
     4621 aaattccatt tgtaacagat gttgattatg aaaatgaaat gatggaattg gaaagtggaa
     4681 gtgcttatcc agatagtgaa tacaattttg gcggaggtgg caatagtgac gatagaaacg
     4741 aagtattgga ccaaacgtcg agaactggag gatcaagcaa ggctcaaaca agaaaatcag
     4801 acacttaaaa aattaactag tgtatttcct gaagcactga aagagataca agcaaaacta
     4861 ttatcacaag ctgacttaca caatatcact tatccagaaa tgatggagtt ttacagtaca
     4921 agtaatcaga aaaaatatcg tgaatatgtg gaaaaaaatt ataagtcatt aaaaatgtat
     4981 gatgcaaaat acaaagagtt tatcgatgaa ttttttccac catttgacta tgcaaaagtc
     5041 aatcgcttat tacaaatacg atcagatgta tttaaaattc ttgcagaata tgcgatggat
     5101 gcagatgtga atcaatattt ttctgatcgc ttagaggaaa ttcttcaaag aacatattct
     5161 tctaatgcta atgtttttgt tcaactttta aacgttgata taccaaatta tttaccagaa
     5221 aatgaaatta aacattattt gaactatcca tggtcaggaa agacattttc aagaagactt
     5281 tggggaaata tttcatcgct tgaacagaaa ctctctaatg ctattgtaaa aagtgttgct
     5341 agtggagaag gcgttataca cgcattaaac accatgagat tagactcaga aatttgtgac
     5401 atgtttaagt tagaagaatc aaagtataac aaagcgatag aaaatctcgt tcgaacggag
     5461 tatgcaaaat ttgcacaaga tggtattgaa aaatcatatt tagaaacagg tattgaggaa
     5521 tacaacgtat tgactgcaaa agatgagaga gtttgccgga tttgtggagg aaaggcaagt
     5581 aagaatccct ataaactgaa agatgctgtc ataggtgaaa atcgagcacc tttccatagt
     5641 cgttgtagat gtacggatgt tcctaattta ccaaaattag gaaaggatat tgatgaagaa
     5701 tatgaccgtt tatttggcga tttattagat gagtttgcac atgattcttt tggaattaat
     5761 ttgaaacgga ggaagtagaa tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa
     5821 tgctgatatt gcagaagcct acaaaacagc tattgagtct gagaaccatc ctaatggctt
     5881 gagagaccat tggaatggca attatgccta cgtggttatt ggcgatcaaa ctgttaatta
     5941 tcaagataat actccagttg ataagaatac cgttaattta acgattcaat tattatctca
     6001 ttcattacca aatttaaaag aaacagttga ttggtatgaa aagatgggat gtattgttgt
     6061 tagaactgac tacaaagaag gaaagtctag taattaggct tttttatttt gtccgaaatg
     6121 acgttaaact agcgcaatac tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca
     6181 aagcaatgcg gggcgtgaaa acgaatcgtg gggcgaaagg agaatgagca tgaaacacaa
     6241 atcattaatg ccaatgaatt tgcaatactt tgccgaaggt gacgatcaaa agttttcttt
     6301 tgatgacttc aaatcttttg tggaatccaa tgaagaagct caaaaattta ttcagtcaca
     6361 atctcaaagt gttgccgaca aacaattgga agcttggaaa caaaataact tagataaaat
     6421 taaacaggat accatcaagg aatatgagga atctaagaaa aacaagtcac ctgagcaaat
     6481 tcaactggaa aaactacaag ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga
     6541 taataaagca tttgttgcag aacaaattgc tggattagaa ctagatggag agttaaaaga
     6601 gtctatttct caatttatgc taaataatct tgttagttcg gatacagatt tcactaagaa
     6661 tgctgttgaa ggttttacaa gtgttttgaa tgcaattaat gagaaacatg cagatgcatt
     6721 aaaagaacta caaatgaagt ctgcatttgg tggaactcaa caatcgaata accaggttca
     6781 gcagaacaat gaaacattaa caaatccaga agaacaatta ggacaaattc ttcaacaatt
     6841 taactaggag agtgaaaaat tatgaaaaaa acatctttaa ataatttaga gtatttggat
     6901 atttcaccag cgattaatgc tatgcaagta ccaaatacac cttttttaag ctatttactt
     6961 ggtgctggaa aaacagagcc agcaaactcg acagaaatta aatggcgtga atatgatatc
     7021 aacaacgatg attcttctga aaaacttgag ggcggagaat atccagatgc tgaatcaggt
     7081 cgaacttggt ttaacaacta tactgaaatt tttagaaaat caacctctgt atctggtaca
     7141 ttagatgcta ttaatgtgaa tggagtcgga aatgaattaa ctaatcaagt agcactacgt
     7201 ggtatggaaa tgaaaattga tttgaaccga aaattgatta ctggtgtaaa agctgatgaa
     7261 aatggttcta aaggtcgtcg aatgaatggg attttgaact tgatcaattc agcaaataag
     7321 gcagaaacag ccactgcggg tgcagtaaca agaaaagata tcgatacttt atttaaattg
     7381 atgtatgaaa aaggttatat gggagaaaaa ctatgcttga tttctccaga tatgcaggag
     7441 ttaatgactg atgagttaga tggaaaatca acaaaaattg ttcagttcgg ggaaagagta
     7501 acttttggat tgcaaattgg aaatatcgtg tctaattacg gtacaggtat tgctctacta
     7561 gaaccatcat tgccaaaagg aacaattgcc gcaatcgata ctaattatgt gaaactacgt
     7621 ccattacgtg aatggagagc agaagaactt gcaaaaacaa cggattctag acgtatcggt
     7681 cttgtaggtg aatactctct tgaatacaat gcttcaaact ctggggcaat tttaaattta
     7741 aagtctgaat aaaagggagt tagtactccc ttttttgata ggaggaatta cagtggtaaa
     7801 aaaagatgaa actaaaaaag atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt
     7861 tgttgggttt gttcatccta aaactcgtag atttatcaca gcagattcaa ataacgaatt
     7921 tatcatttct atagatgata aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa
     7981 tgaaatttag gaagtgatct gatggatgaa tcgctaaaaa cggaaatcat tgagtctaca
     8041 aaagaagatt ttccagattt gagtgaagaa cgcataacta atttattaga aataattttg
     8101 ctagaaattg aatcatacaa cacttgtaaa aatgatattt catgggaaaa gttaaaaagc
     8161 gtgattagtg aagtgttgta taaaataata aaaaatgaat cagaaaaaac agtatcttca
     8221 gttagacgtg gcgatacaac gattagttat gcttcaacaa caaatgatgt tagtgagtta
     8281 cttctaggct atggtgattt gatacgaaga gttattggtt gtggaggatt ggagtttttt
     8341 taatgaatga agcagatatt ttagaaacta cttatgaaga tagttgtatt attgaaagac
     8401 tgacggacat tgaagattct aatacaaata ttactattca agattacaaa aaagtatatg
     8461 ataatcctat ttcttgcgct ctttcacaag gtcaaatcga tggactagca gtcatagaag
     8521 atggagagat ggtaaatgtt tcaactgaca catataaatt atttgttcat cctaagatta
     8581 aactaaaaaa aggagatcga ataacaataa ctcaaaaggc cagtggctta attttttctc
     8641 tatttgctac taagcctttt tactatccta gtcattgtga agtgaatttg ataggaagtg
     8701 agaaaaatgg gtaatctcaa atatgaatca aatgcagaaa agatcattga gaattttaaa
     8761 aatatgactg taattgctca aaaagaagga atatccttcg ttaacgattc aatgaataaa
     8821 gtcgttagtt tagctaaacc attaactcct gtaaaatcag gtaatttaag gcgaggatat
     8881 cgtgtagtaa aagctagaaa actatcaagc ggtcgaattg ttggagaagt tataaacaat
     8941 gaacattatt ttaaatatgt agaagaaggt cataggacta aaaatggtgg ctttgtcaaa
     9001 gggaaattca tgttaactcg tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga
     9061 tttaaacaaa tggcaataaa aatcgttaag aaaggaaagt aacatgaaag atgaaatcat
     9121 tgctgcaatc agtagcaaat taaaagaaat ctatcctgat gggacaatat atcttgattc
     9181 agttatgcag tcaactaaag atttttattt cgttttatca gtaatggaat ctggaactga
     9241 aaatgtagga attgatattc aaaatgtttc tttcttaatt gatattgcat tgattgataa
     9301 taaccctaat agaaatttaa ttaatgaatt agtctcacgt tgtgggactt tttttaatac
     9361 gattacaatc gatgagcaaa tattatttcc aaaagcctat ttacctgatg aagcagatgg
     9421 tgttcaacat attcgtttta cattagaatt tccacaatat attgaatgga gtgaaagata
     9481 aatgggagaa aaaagaagta aaaccggaat tatttctgtc gaaaaaccta cttggtttcc
     9541 tttggaagat gagacaggga attttccggt atatggtact gcgttgccaa tgggaacagc
     9601 agtaagtatc aaaccaacag ctaattatga aacaacacaa gattatgggg attcagtggt
     9661 tcaagatcaa tttacagctt ttggtggtgc agaagttgaa ctggaagcaa atggatatac
     9721 tcataaagtt ttatctacaa ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc
     9781 tggagaagat attgcgcaag atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa
     9841 ataccgttat acggtctttt ataaaggaca gtttgctcta gattcagatg aaacatcaac
     9901 gattgaagga agtaaagtaa gttttactca tccaacttgg aagggttcat ttgtagatgt
     9961 accaggactt ggatatatgt attcagttga tgaagatgat gaaggcgtgg ataaagcaat
    10021 gatcggaaat tggtttacaa aagtagcaat tccaattgaa gaagcagaac tttcaggagg
    10081 tacagaataa tgtcaaaata tcaaacaacg attaaattaa cgaaaaaaga cgaagaaggt
    10141 aaatatgagc aagtacaatt taaatctgct gaatttttac caggaacagt tgtagaagat
    10201 gctgcaggag ttatggaaga aatgcaaaca gcgactgata agcaatcagt taaaaaagct
    10261 ttaagtcgtg cttattcatt tattgcagat actttatttg agggacaatt tactggtgaa
    10321 gattattgca aaggaattga tgctcgtgag attgcctcat tgacaggaaa attattgaag
    10381 tctgttactg caggttttga tgaaacttat acagagacga aaaaaaagta agtgaggcgc
    10441 tcaagtcacc ttcatttaag tattcgatta cttaccgaga attagatata aagacgcaat
    10501 tactcgaagc aggttggacg ttaccagaaa ttgaacgtac tgacttggat gagttaatgc
    10561 gtctttttgc ttttagagat gcggtaaaag agcatgaaga tgttgagtac tatgataatt
    10621 tcactcaatt ttaggaggtg atactttgaa taacgatgac ctaattctga agatgatact
    10681 agatgaatct ggttttactg ccggtatgaa taatgctgtc aaaaagttga actcttttga
    10741 tgaaacaatc gaaagaaaaa gtagaaatag tggcagttca ttaggtagta tttggaaaat
    10801 atttgctgga agttttctag ctagcggagt aactagaatc gtaggagctg gctttgatct
    10861 aatcaagggt tccataagtg gagcggttga tcgagtagat acgatgaata acgctctacg
    10921 aaatttccaa aatatgggat ttagtaattc agaaattatg aagaatatcg gaaagaatgg
    10981 gcttttatct caaggtattc aaggacttcc tactgctttg aatgatgcga taagtcatgt
    11041 tcaacttctt gcttcttcta caggtgattt aactcgttca actcaaatat ttaaagcttt
    11101 aaatgatgga attcttggtt tcggtggttc aactgatcaa gttaatgaag ctgttattca
    11161 attatctcaa agtttctcaa acggaaaagt agacgcacaa acttggaact caatgatcaa
    11221 cgctcaactt ggacctactc tttctgctat tgctaaaaag atgggaatta caatgggaga
    11281 tctgaaagaa ggtttatctc aaggtaagat ttctgttgaa gaattccaaa atcaattaat
    11341 agaaatggat accaaaggtg gcggaggact taaatcatta agtcaaatcg ctaaagattc
    11401 tactaaggga attaaaacct ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg
    11461 tgaggtaata gaaggattaa ataaagcatt agtagattca gatttaggtg gatttaaggg
    11521 aattattgat aaagtgggca gttcaatgga atcgttctta aaagtaattg ctgcaaatat
    11581 tcctacagca gtatcatttt taagtaattt atttaacgaa attcaaaaat ttggttctgc
    11641 tttgaaattc atgatgccct ttcttgttcc tgcagctacc gcttttggag cgttcatgtt
    11701 tcaacttaaa ggtataccag caataataaa aagcttcaat aattttaaga atgccataat
    11761 tggcgttgga aattcattaa agattatggg ggcaatagct gctgctaatc catttgtttt
    11821 aattattggt gcagtcgttg gtgcaatagc tgttttcggt tactttatgg caaccaatga
    11881 agagcttaga aacaaggtta tatctatttg gaatgatgtg aaagattccg taattggtgt
    11941 attaaaaaat ataaaggact ggggaattga tacttggaat tctgctaaag aaatggcatc
    12001 aaatgcagtt gagggtgtca aagatgcttg gtcaggaaca aaggaatggt tttctaacac
    12061 ctggaaaggt attaaggatg gggccacagg tttatttgat aaaacagtag agacttcaag
    12121 aaatgcagtc gatagtgtaa aaaatgcatg gtctaatatg aagaaatggt tttctgatac
    12181 ttggcaaagt ataaaagatt cagccagaga aaaatggaat ggaatcaaag gttctattat
    12241 gtcagttgct ggtccattga ttacaggtat aaagaatgca tttttacatg ttacttttta
    12301 tctagagacc ttatggaata atttagttga gattggtaaa aacgtctttg agattttaaa
    12361 aaatgttata cttgcgccgg ttttgtttat tacctccatg atttctggtg gatgggaaga
    12421 aacaaaaaat aatatgattg ctgtttggaa taatattaaa gaaagtgcca taaatatttg
    12481 ggaatctata aagaatatat ttgtaagtta ttttacaaat atttattttg ctgcactcaa
    12541 tatttggaca gggttcaagc ttacattgat aaatatttgg aatgaagtgg taaatcaagc
    12601 taaatcgatt tggttaaaca taaagtattt ttttattaat ctttggattg atataaaata
    12661 ttttgcaatt cagaaatgga ttgaattgaa gttttctatt attcaaactt ggatcgattt
    12721 aaaatataat gccattacta cttggaataa tattaaacag tttttcaaag atacttggaa
    12781 aaatattaaa gatacggcat acaatacgtg gatttctata aaaaatacca tgattaatac
    12841 atggaataac attaaggact ctttctggaa tattgttact ggaattgtta attctgctga
    12901 aaatgcatgg acaaatctaa aaaatggtgt ttcaaatgct attaatcggg taaaagaaat
    12961 ctttaattcg ttaagggaag tcaatttatt tgaaattggc aagaacatca ttgatggact
    13021 tataaatggt gtaaaagaaa agtggaatgc tttgaaagat actatcaaag gtattgcagg
    13081 taatatcaaa aattggatta aaggagcttt agatattcat tctccatcaa gatggatgcg
    13141 tgatatggtt ggtaaaaata ttgttcaagg tattatcgtt ggtattgata aagagcaaag
    13201 taagttagat caaaccatga caaatttagt aaaaacaccg tctgttcaac ctgtagtaaa
    13261 tggaataagt cacctaccaa ttacacaaac aaagcaaaat atatctgcta gtgaaacaaa
    13321 agaaattcat ttacatttaa atgtttatgg agatttacct gattcaatgg ttcggaagat
    13381 taccacaaaa attaaaacag aattgacaag acaaatgaaa cgagatgctg gtgcagtagg
    13441 aggaacatta tatgcaactt aagagaggac aattttttat taatcaacat tattcttctg
    13501 aatttaatgt gtatattcaa aacaggcctg cttctgtttc agctagtcga gtaattgaat
    13561 tgagagagcg agaaggaaat gattctatca ttattgataa aggctattac aaaaatgtga
    13621 ctagaaagat tgagtgttac tataaagcac cttcaattga tatggtgcag gagtgggaag
    13681 atcgaatcac tgaatggtta gatatgtcgt cttatagtga ttttattctt tactatgatg
    13741 aacaatatat ttatcaagct gtagtaatag aaggacctga atttaaagga acaagaaaaa
    13801 caggaaatat tgtccctttt gaatttacag tgagtattcg accatttaag gaaaattaca
    13861 atggtagatt tactattcga caaacagaaa cttttgaaat ttataaccca gagaagtatt
    13921 cttcaaaacc gcttattaaa ttgagtggtt ctggagatgc ttctttttat attaataagg
    13981 ataaatatga tttgaaatcg ttggacagag aattatttat agattctaaa ttagaagagg
    14041 cttatcgaaa attagatggt aatttagaac atcaggatca ggtcacctta tttttagatt
    14101 ttccattttt atatcctgga aaaaatgaaa ttaaatggac gaaaaatatt cattcatttg
    14161 aaataatgcc taggtggtgg agaaaagtat gaaaccaaga atatatagtc ctactgaaac
    14221 agatttctca acgaatggct taggaatttt aaaggattgt acaagatgtg gaatatatga
    14281 agtagctaat ggaaaatatg aattagagtt ggattatcct ttaggaacta gatttgatga
    14341 atattttgaa aatgactatc aaataaaagc aaagccaaac gatcaagaag agtatcatat
    14401 cttttttatt gatgataaag atatagatac ttttttaaat acagtaacta tttatgctca
    14461 gagtcgtaca aatcgacttg gaagacgggt agtcactctt gtggaagtgg actctaaaac
    14521 tggtcaagaa gcgatatcaa ttattgaaac taaaatggat aaaaaatctg acatacgact
    14581 ttattctgat attacggctg tttctagcac aatctttgaa gcgagaaatg ttttaaattg
    14641 tattgctggt gaacaaggat cattgcttca atattggggc ggagaaatta aacgtgaacc
    14701 atttaagctt tctttgttaa agcgaagagg tcgcaataat gttggaacga ttcggtatgg
    14761 aaaagatatg tctggtttga aggtcaaatt agattggaca ggtataaaaa caagaattat
    14821 tccatatgct gatcctcaaa gtgaagtagg tacgactaat cgaatttatg gttcgccagt
    14881 agatagtgcc tatattaata actatcctga tgtctataca gaacatgttc agtttacaga
    14941 agaacaagga gtaaaagaca ttaagagctt aaataaaata gctaaaaatt actttaaaac
    15001 gatcaatcct ggctgtgata agcctaaagt ttctattacg gttgaatttg ataagttgac
    15061 tgatagtgaa gaagcgaaag aatttgcgaa gattagaaat tatggtctgt ttgatacatt
    15121 taaaatatat cataaaaaat ataatattta tcttgaatca aaggttagtg gactacaata
    15181 cgattcttta tctgaaaaaa ctttgaaatt agaagcagga gacattcaag ttgcttttta
    15241 tcagcaacaa gctgtaacta ttcaggataa attaaaagat tatgcaacga ataattatat
    15301 gagtgatttt aatgattatg tttcttcaat gattacaggt caaggcagtg caggaggata
    15361 tgtagtttta tggccaaaag aaaaaccttc caacatcttt attatggata atccagattt
    15421 agaaaaggca agagaagtac taagaatgaa taaaaatggg attgcttttt ctaagaaagg
    15481 atggcggggg ccttttaatt cagcttggac attagatagt atatttaatg ccaattttat
    15541 acaaactgga ttaatcaaag cagatatctt tcaaaattct tttaacaaga ctggagatgt
    15601 attgaaatta gttaatggac tactccaaat ttggaacaac aaaaagaaaa taatggagtt
    15661 aactaaaaaa ggaatggaat tttggaattc taagggttca attggaacga ttggaacaac
    15721 tgattctgtt ggtaatcctt ttcctggggc ttctactcca acccctattg aagataattc
    15781 tttagttatt cgtacaaatg gagacggcaa atatattttg atttctccta aagtaggaaa
    15841 aggattagtt ttattaggaa atggtaaagc aatttatttt ggagacttag atgtacaagg
    15901 aaaacttaca gttaaaggaa aagaaataat tcctggacaa ggtggtggtc catcgggagg
    15961 tggagaatct actggtgggt atcctagtga attaaaaaca gatgcagaaa agagagcttg
    16021 gagaatttac gatattttgt gtaataacgg atttacgaaa caatctgcat gtggaatatt
    16081 ggggaacatt caacaagaaa caggaggaac ttttgatcct gatactgttc aaataggtgg
    16141 accagcatac ggattagttc agtgggatgg ttcttcatat cctcttgttg gtccagcaac
    16201 atgggatgga aaagtttatg ttcaaaactt atttaatgct gcaggtatta aagaaccaat
    16261 aacgagctta gatgcacaag ttcgattgct tatttggaca tttacaaatg gacaatggat
    16321 gggcgtagta caacctacga cggttgatgg atttaaggcc tgtactgatc caagacaagc
    16381 agcatatgct tttgaacgaa actatgaacg tccggcagcg acacatcctg aacgtcaaga
    16441 ttatgcagtt aactggtata acaaatttaa agatttaaaa ccaggaggag ctactggaga
    16501 agcaggacta aaacatttag agtctttgat tggacaacga attggcaatg gtcagtgtta
    16561 tggcttgtct gcagaatatt caggatatct gggtggttgt ggcatgggtg ctggaacaaa
    16621 atatggttta actcatgtga taggaaatac ttctgcagca tctgatattg gtattgccta
    16681 tgattggtct gctgttggtt ggaaagtgat tcaaaaccct agatatgatc aattagtagt
    16741 tggtgcaatt attaattggg caagaggtgg acaagtgggt tcatggtttg cagatggaac
    16801 ttatggacat actggcgtta tccgaggctt agctaatggt cgtatgcaaa cttatgaaca
    16861 aaacacagag ttaggtatga tttgtggaaa gttagatcgc cagtattata gtgcaagtgc
    16921 aatttcttcc attgtcatac caccaaaata gggaggtgat ttaatggcaa agtggaatgt
    16981 catattaagt acaacagaac cctataatta cgtggggatg attcaagttc gacaaggcaa
    17041 taagaataca gaggttatgg aagcgactat agttgaaaat ggtcttccct acgatttatc
    17101 agaatgtaag gtatattttg aatcagttgt aggtgggaaa tatccagtcc aattagaaac
    17161 aaaaattgtg gatgctaaaa aagggaaaat taactatatt tttgataaat attccatgca
    17221 gtgtttacat cgacaaacag ccaatttcat tatatttaaa ggagaagact tgattggaac
    17281 aactcaagac ttctcttatt ttgtcattaa tgctgtttca aaaacagaag gagaaatggg
    17341 ttcttattgg caatcaatcg aagatttaat tgcggatatg acggacttta ttaatgaaaa
    17401 taaaggcgat tttacggact ggatgaatga aaggaaagaa gaatttgaac gttggagaca
    17461 agaacaggaa cacagtttcc aagattggag agaaggacaa gaatcagact atttggcatg
    17521 gtttgaatca atcaaggata ttttaaagac gattgatcca ggtggagtca tgttagccga
    17581 actaacggat gcgcgagtag atattcaagg agttcgtcat gcgtctattt cagagcgttt
    17641 gctggcagat atggactatt tatatcagaa attgcgagca acgcttttca cgattgaata
    17701 cggggagatt gaagtgactg atattttgca ggatgatctc ttttcagata atcatgaagt
    17761 cgaaaaagtt ggaactgtag cattcccgat tgaagaagga gccttgatca tcgcaaccgt
    17821 tgatgatcca aagcaaaatg tgttcactct tgagaaagtt ggggtgatct aatggctaaa
    17881 actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac aacgccaatt ctttccaatc
    17941 acacatgctt ccgcagttct tgggttagaa gaaataatag caggagaagc aacagtttta
    18001 tctgttaatg gaaaaattgg agccgtcgtc attactaaag aagatttggg attagagaat
    18061 gttctcacag aattacccta tgcaagtgaa gaagatgacg gcattatcac ggcagaaatg
    18121 tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt tgccagttgc cactatcgac
    18181 cgtttgggtg gcataaaagt tggtgaatta ttgacgattg atgagacagg gaaagtctct
    18241 gcagtcagac aatctgatgt caatttttcg ctggagttaa aagaaaaact cgattcactg
    18301 aaaaattata ctgctggaga aaacatcact attgatgaag atggaacaat tagttctaca
    18361 ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag atcaaaaatt ccaagaagct
    18421 gtaaatcaag cagaaaatta cacaaacgaa agaattccaa attttacttt tgaaaaaatt
    18481 ggggaggtat agagaatgac agatatcgta aaaataaaac aaagcaatgt acaggtttat
    18541 ccacaaactc attggaatgc tatagaaggc aaaccaacaa cggtgaaggg agataaaggc
    18601 gatcctggcc aagcagcaac aattaccata ggaaccgttt ctagtggttc aaccgcttct
    18661 gttacgaatg taggaacatc atctgcagct agatttaatt ttgttttacc aaagggagat
    18721 aaaggtgatc ctggaataaa tgccacaact acagctgtag ctacaactac agcaaatggg
    18781 ttgatgtcgt ccacagataa aactaagttg gatggaattg cagctggagc acagaaaaat
    18841 ccaggtaatg ctacaactac gacagcaggt ttaatgtcag caactgacaa agctaaactc
    18901 gatggattag ccaatattac atttgagaaa gtggggacgg tttaatggct gatattgtgc
    18961 aattaaaaga agacggagtt gctaaatact taaaaacgca tgtagaagct attgatggta
    19021 aagaagcatt ggtgcagaca gatggagacc aagccattgc aggacataag aatttttcag
    19081 gttctgtaac aatcaataat aaacgtgttt tgacgactga tgataacaga tatgaagtgg
    19141 taaatctggt tgtcactaac ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa
    19201 cagtttctat atattttgtg gctttaaacg gaaaaagtag tggcgggaat gattcggtta
    19261 ttttaactgt tccagaaggc tatcggacac caattagttt tgaacaactg gttgggtcaa
    19321 tagaccgttc tactttgaac agtgctcaac tatctattgg cgcagacgga gccattaaat
    19381 ggagaagaaa ttcaagttat ggatcagctt attcatttgt tatcacttat tcaatttaag
    19441 ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc cttacggatt cgagcaaatc
    19501 attttgaaca atcaagaaaa tatccctgaa aactgtacag agattaaacc accagttcct
    19561 aactggagac caagatttga ttttgataaa aaacagtggg ttgagttagc tactgaagaa
    19621 gagaaaaaag ggaatgctgt tgatagcgta gatgaattgg ctaatattaa ggcattatac
    19681 gaaacgctga aggcagaaaa tgatgaattg aaacagctaa attctaaagc aatgctaaac
    19741 aatgtagcaa tcaagcaaga aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag
    19801 ttgaattcaa aaacgatgct tgcttctgta caaaatacca aggaaatcga agaaatcaaa
    19861 aaacaattac aaggtgggaa gtaacatgta ttcatatgaa gatatcaaac taatgtatga
    19921 ctggggctgt ttcactaacg aacaagtaat ggttttcgtt ccgttgtgca ttactgaaga
    19981 agaagcagat aaaatcatta gcaaagaaga gagcgcatct taattgatgt gctttttatt
    20041 ttgattcaag gagttgtcac atgattaatt taggggaatg gggagcgata gcaggatcaa
    20101 taaccgctat cgtttctttg attttattag taataaaacc aattactgca tctttctcga
    20161 agattactga gactctttca aaagtaagtc acaatttaga tttgctgact aaagatttag
    20221 aatcgagcaa atcagatcga ttgatgattc atgaagaact aaagaaacac gatgaaagat
    20281 tagatacaca tacag
//
LOCUS       DASHXG010000048        19682 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.049, whole genome shotgun sequence.
ACCESSION   DASHXG010000048 DASHXG010000000
VERSION     DASHXG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.049"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            311..1090
                     /locus_tag="U2R59_002061"
     CDS             311..1090
                     /locus_tag="U2R59_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966417.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            1136..2080
                     /locus_tag="U2R59_002062"
     CDS             1136..2080
                     /locus_tag="U2R59_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEM8966418.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="U2R59_002063"
     CDS             2096..2875
                     /locus_tag="U2R59_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HEM8966419.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="U2R59_002064"
     CDS             2887..3585
                     /locus_tag="U2R59_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HEM8966420.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="U2R59_002065"
     CDS             3613..4377
                     /locus_tag="U2R59_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEM8966421.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4421..5872
                     /locus_tag="U2R59_002066"
     CDS             4421..5872
                     /locus_tag="U2R59_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEM8966422.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSCVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5904..7040
                     /locus_tag="U2R59_002067"
     CDS             5904..7040
                     /locus_tag="U2R59_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEM8966423.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            7040..8146
                     /locus_tag="U2R59_002068"
     CDS             7040..8146
                     /locus_tag="U2R59_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEM8966424.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            8152..9174
                     /locus_tag="U2R59_002069"
     CDS             8152..9174
                     /locus_tag="U2R59_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HEM8966425.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            9196..10251
                     /locus_tag="U2R59_002070"
     CDS             9196..10251
                     /locus_tag="U2R59_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEM8966426.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFIIL"
     gene            10869..12104
                     /locus_tag="U2R59_002071"
     CDS             10869..12104
                     /locus_tag="U2R59_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966427.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALS
                     GAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGAR
                     LSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIYIE
                     VGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYLTDNTLTYPDTQMI
                     FLLVPMIVSWVDNQQRISE"
     gene            12188..13276
                     /locus_tag="U2R59_002072"
     CDS             12188..13276
                     /locus_tag="U2R59_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966428.1"
                     /translation="MKKILVLANTYYQIIVAIQMKNTIFSDEYVEIIISDHSKNTKEI
                     AKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFD
                     EFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLK
                     KRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKY
                     IFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSS
                     IPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAY
                     DIERLLKQKTMKNILKNVKIAESLDDIL"
     gene            13273..14694
                     /locus_tag="U2R59_002073"
     CDS             13273..14694
                     /locus_tag="U2R59_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEM8966429.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIMIILIIINIS
                     YIKQLCYRGRNIISMIKSREHKR"
     gene            14730..15446
                     /locus_tag="U2R59_002074"
     CDS             14730..15446
                     /locus_tag="U2R59_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HEM8966430.1"
                     /translation="MVDNYERKNILKKKSIGCRMKIVAIVPMKLNNKRLPQKNTKAFT
                     NGKPLCYYILSTLLKVKQIDKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQV
                     LAGFTKEVEADVYVMTHTTAPFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGE
                     PFNYELDNIPRTQDLPPLYEETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDID
                     EAEDFMIADAIYNHLILQGS"
     gene            15465..17048
                     /locus_tag="U2R59_002075"
     CDS             15465..17048
                     /locus_tag="U2R59_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HEM8966431.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            17183..17761
                     /locus_tag="U2R59_002076"
     CDS             17183..17761
                     /locus_tag="U2R59_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966432.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            17707..18225
                     /locus_tag="U2R59_002077"
     CDS             17707..18225
                     /locus_tag="U2R59_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966433.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            18233..19273
                     /locus_tag="U2R59_002078"
     CDS             18233..19273
                     /locus_tag="U2R59_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEM8966434.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            19522..>19682
                     /locus_tag="U2R59_002079"
     CDS             19522..>19682
                     /locus_tag="U2R59_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8966435.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         7180 a         2484 c         3841 g         6177 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attctatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttatggaaat aaaaatgaaa tcgattaatt tttatcttat taatgtttta
      121 tttactttta aatcgtaaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt tttttaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggatacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctctgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttatttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatatct aggattcgct gatattcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttaaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggtgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctgag caaatgggct atagcaatat
     1081 aagctattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc acagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaactcgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttccaatcg gtaaaattac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagacc caaatggtga ttacggtaga caagggcgcc aaagaaagat
     1801 cgtagaaggc gtagcgaaaa aagtattgag tctaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgaac tttgatgaaa tgaaaaaaat
     1921 tgctttagat tatcgggagg catttggtac gattaagcaa gatcagctgc aaggagaagg
     1981 cttcatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtgaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc agcttgaaag aaatttttga aacattacgc aaacacttgg taataatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca ctgcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtgctc aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tgaacaaatc aaagatgcca tctcagttaa tcaggcagaa aattcacaaa tgttctcgat
     2461 tcaggcaata agtacgaatg cagtggctgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag atgtgatgaa tgttgataaa atctcgatca tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatttaatga ctggcttaat
     2641 gttaggaatg atggtaggtg taggtctggc attcttattg gaattactcg atcggacagt
     2701 gaaagatgaa aaatatgtga cagatacatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga atgctggtat ccgtaaaaaa ggaccagctc agacacaacc
     2821 aaaagctaca aacgataaaa cagcgccatc acgcagaagc cgctcaagag tctaggagga
     2881 aagaaaatgg cacgaacaca gaaacaaaaa gcagcccaaa ctcatgcagt cagtttggtc
     2941 acactcacca atccctcttc accaatcgct gaacaatatc gtacgattcg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg ttgtgacttc atcaggacct
     3061 ggagaaggga aatcgaccac tgcagcaaac attgccgttg tttttgccaa atctggtcaa
     3121 cgggtgctgc tagtcgatgc agacttacgt aagcccgtca tctataaaac gttcaagttg
     3181 aacaacgcaa gcggattaag tactgttctt agttcatcag gaagtgtagc agatgagatc
     3241 caacgaacac cagtcgacaa tttgtcgatt ctgccaagtg gacctaaacc accaaatcca
     3301 tcagaactac taagttcgcc aagaatggat cagattttag cagaagcaag acaactattt
     3361 gatgtagtga tcttcgacat gccgccagtc gttgccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacctt attggtcgta cgggaaaata cgtcacgaaa agaatcattg
     3481 actaaagcaa aagaactgtt agatatggta caagcacgag tcttaggtgt cgtatacaac
     3541 ggagcagaac acagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg cattacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aacggctttt ttttgagttg ttagaactag gaaagatacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaact tactgcgcca agttatgttg gtgtatttgg caaagatatc
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgca
     4201 cacggggtct ctaagcgcac cttttactta aaagagtgct atgagcagat tgccaaggag
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gagatcaatt atccaatcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagtgagag atgtatagaa aaaactcaag
     4441 tggttggtct aaacatattg attttatttt attagactta ttttgtgtcc agcttgcttt
     4501 ttatatatca tatgtaatgc gacagggtga ctggaatccg tatgtgattc ctatttatcg
     4561 ccacatggca atttttatag aacttgagaa tcttacgatt atatttttat ttgaggcata
     4621 taaaaatgtt ttaaaaagag gatattataa agaggctgta gcttctataa agcaatcttt
     4681 tatgctgtta cttgtgtgca gtttatacct tattacaatg caggatggaa atgattattc
     4741 cagagtttct ttatttataa tgggggtggt gtatggatta ttaacatata taattcgtat
     4801 actttggaaa gggttgttgc atcaccgcat gaaaaacggt gaagatgtat cgttagttat
     4861 tgtaacatct caaaagattg caaaaaatgt agttcgtaat cttaaagaga agaattatgg
     4921 catgtataaa cttagttgtg tgattgtagt agacagagat atgtatggaa ctaccatcgg
     4981 aggtgtccca gtagttgcaa atgctgataa tgcagcggaa tatcttttac agaattgggt
     5041 agatgaagta ttcatcaatg ttgacgaaag tgttccatat cccaaagaat taatcgccag
     5101 atgttcggaa atgggacttg ctgtacatat gaatcttaca aaagtgtctg atagtacacg
     5161 tggaaaacaa tttattggcc gagttggtga ttatactgtt attacatcta gtattaatgt
     5221 tatgacgatg aggcaagcat ttataaagag aacgattgac attcttgctg gaattattgg
     5281 atgtattgca acaggtgtta tttttatctt cgtagcacca gttatttaca tcaaatcacc
     5341 agggccgatt ttctttgcac aagaacgtat tggtcaaaat ggtaagacat ttaagatgta
     5401 taagttccgt agtatgtata tggatgcaga agaacgcaaa gcagagttga tgaaagaaaa
     5461 taagatgagt aataatctca tgtttaagat ggattttgac ccaagaatca ttggcaataa
     5521 aatacttcct gatggaacaa agaagacagg aattggacaa tttattcgat ctacatcatt
     5581 ggatgagttt ccacaatttt ataatgtcct aatgggaaaa atgagcctgg tggggtttag
     5641 accttgcttg aagtcagaat atgagaagta tgattttcat catcgtgcga gaattgcgat
     5701 gaaacctggg attactggaa tgtggcaggt gagtggtaga agtgatatca cagacttcga
     5761 agaggttgta aaacttgatg cagaatatat caggaattgg agtatgggat tagattttag
     5821 aattttgttt aggacagtca aaactgtgct tcatagaaac ggttccatgt aagataaaga
     5881 tactatagaa ggagtaaaac gtgatggcaa gaaaaaaatt aaaaatctgt atgctaggtc
     5941 ataaaagaat tccatcaaga gaaggtggaa ttgagatagt ggtagaagaa ttggcaacgc
     6001 gaatggttgc acttgggcat gaagtgactt gctataatcg aagtggtcat catgttagcg
     6061 gaaaggaatt tgaccagcat aaaaataaag aatataaagg tgtaaaatta aagactattt
     6121 ttacattaaa tataaaagga attgcagcaa tgagttcttc agtatttggt ggaattagag
     6181 cagcattcgg aaaatatgat attgttcatt ttcatgcaga aggaccatgt gctatgttgt
     6241 ggttgccaaa actttttggg aaaagatgtg ttgcaacaat tcatggtcta gatcatcaaa
     6301 gagaaaaatg gaacaagctt gctagtacat acatcatgtt aggggaaaag tgtgctgtaa
     6361 aatttgcaga tgaaataatt gtacttagtg aaagcgtcca aaattatttt gaagatatat
     6421 atggaagaaa aacaaggttt ataccaaatg gcgttaaaaa aattgaaata aaatcagcag
     6481 gattgattac agaaaagtat ggattaacaa aagattctta tattttgttt ttggggcgat
     6541 tggttcccga aaaaggaatt cggtatctaa ttgaggcatt taaagatgtt cagacagata
     6601 aaaaacttat aatagccgga ggaagctctg atacagatga atttgcaaat gaactaaagg
     6661 aattagcaaa aggtgatgag cgaattatat ttactggatt tgtacaagga caggaattag
     6721 aagaattata tagtaatgcg tatatctata cacttccaag tgatttagaa ggaatgccat
     6781 taagtttgtt agaagcaatg agttatggga actgttgtat agtttcaaat atctcagagt
     6841 gtacggaagt agtagaagac aaggctatga tttttaagaa atcggatgta agtgatttaa
     6901 agataagatt agaagaggca tgcaatcaat cggaaatggt taaagttttg aagaatcaag
     6961 ctactgagtt tatttgtagt aaatataatt gggataaaat cgtacaagaa acattaaatt
     7021 tgtatagggg aaatatataa tgattcgaat attacagtgt gtgaatgata tgcatcgtgc
     7081 agggttggag acgatgctaa tgaactatta taggaatata gatcgaacta aaattcagtt
     7141 tgattttttg acacatcgtc catataaaag tgattatgat gaggaaataa taagtcttgg
     7201 aggaaaggtc tattatgcac cgagacttta tccacaaaat tatcctaaat attttaaatg
     7261 gatggaacaa ttttttaagg atcatccaga atatgagatt gttcattctc atattgatgc
     7321 gatgagttat ttacctttaa aagctgcaaa aaaagctggg attccgatac ggatagcaca
     7381 tagccataat acatcgatag atagagattt taaatatctt ttaaagcaat attatcgatg
     7441 taagttaacg tctgttttga cacatgaatt ttcatgtgga aaagtagcag gtgatttttt
     7501 gtttcgaaat gataaattca ctttgattcc aaatgcagtg gatgctaaaa aattttatta
     7561 tgatgaaagt attagaaatg atgtacgaat gaaattagga atttcaagtc agacgtttgt
     7621 aatgggacat attggaagaa tttcatattc taaaaatcat cgttttttga ttgaaatttt
     7681 taaagaattt cacgctatta agaataattc cgtattatta attattggaa ctggtgatat
     7741 ggaagaagaa ataaaaaatt atgcaaagaa aagtggcata gatgatgata ttaaattttt
     7801 aggaaataga aatgatatag aaaaatttta tcaagcattt gacgtattaa tgttgccatc
     7861 attatttgaa ggggttccgt tagtgggtat tgaagctcaa tttgcagatt taccgtgttt
     7921 cttttcggag aaagttccta cagaagttgc tttcagtgat aagaccaatt tcataagttt
     7981 aaatcaatcg gcaaaagaat gggcgagaga gattgcaaat gtagatatct ctcatcgaga
     8041 ttcagaacgt tcgattttaa taaaggcaga ttataatatt caaacagcat acaaaatctt
     8101 agaatcaaaa tattatgagt tatttgaatt aatacaaaga ggttaaagaa tatgacacag
     8161 aaacattcaa gtataaaaag aattatacat cgcatatccg aagaattgaa tgcaacaaga
     8221 cgaattgcaa agataacatc ttggaaggaa gcatttgcca cgttacaagc taaaattgat
     8281 attcaagtca tgaatcgtaa tggatataat gaaagtaaaa aacagaagga acatttatta
     8341 aaaaaacatg aggtaatgct gaagtattat gaaaagactt tttcagattt tttgaaaaca
     8401 tatgattata gtcaaaatca aataattaat caatcaaaat caccatattc taactgcatt
     8461 tgggtttgtt ggtggcaggg attggatcaa tcgccggaaa ttgtaaaagc ttgtgtaaaa
     8521 tcaataaaac gaaatgcagg gaaacatact gttataattt taacagaaga taattataga
     8581 caatatgttg atataccaaa atgggtggaa gaaaagaaaa acaaaggaat cattacgaga
     8641 acaaattatt ctgatttatt aagattatct ttgctagcaa aacatggagg tttgtggtta
     8701 gacgccacat tttattgtac aaaaccaata ccagatgagt attttgatat cgatatttgg
     8761 tctattagga ggcctgatta tgctcacgca tccgtagcat caggatattt tgcgggttat
     8821 tcattagcat gtaatcaaga gtctagatgg atgtttgcta taattagaga ctttttttta
     8881 aattattgga aaaataatga tatgatggtg gattatttga tgatagatta tatgattgtt
     8941 ttagcacaga gaataaatca tgaaatagca cagacatttg ataaaatacc tagtaacaat
     9001 ccattatgtg acgaattgat taaaaattta aataatatat atgatgaaaa agtatggaac
     9061 ttattaaaga aagatacttt actgtttaag ttgacatgga aacaatcttt taaaaagcaa
     9121 aaagatgata aagttacttt ttatgggatg ttggtagaaa acaaattatt ataaatatta
     9181 gaggtataaa aagttatgaa acacaaggta agtgtgatag taccaattta caatgttgaa
     9241 aaatatttaa gaaaatgtgt ggatagttta ttgagtcaga cattaaaaga gatagaaatc
     9301 gtattagttg atgatggttc gccagatgct tcgggggaaa tagcagatga gtatcaaaaa
     9361 aaatattcta atgtaaaaac aatacataga gaaaatgggg ggttaggacc ggcaagaaat
     9421 acaggaattg agaatgcgac aggagaatat gtggcttttc ttgattcaga tgattgggta
     9481 gaaagtgata tgtatgaaaa attatactta gttgcgtcca aagaaaatgc tgatatagta
     9541 gttagtggac attgtgattt tgcgaatgac aaagctatgg tgaaaaagca acatcctttg
     9601 agtgggaatg tatatgatac gcctaatagt attaaaaatg tacgaaaaaa tttatttgga
     9661 catagtccaa aagatcaaga agtagaggcc ttcccgatgt cagtatgtat gtctttgtat
     9721 aataaaaatc tgctagataa atatagacta agatttgaaa aaattttatc tgaagataca
     9781 atttttaact tgaatgcata tgatgtcgca aataaaattg cttttacaga atatacagat
     9841 tattgttata gaaaagaaga acaagagtct attacaaaaa gtttatctcc aaataagcag
     9901 acggaattta aagaattttt aataactcta aaagctatag catcgaaaga agatttagaa
     9961 tgtcaaatca gagcaaaacg tatggcaatt gattattgta ggctttatgt gggcttagtt
    10021 gatgatgcaa atttgggaat taaagagaaa agaaagtata taaaaaaatt tattgaagat
    10081 gagggattaa ttcaatgttg gaagggatat cctacaaata cgctaccatt tcaacaaaaa
    10141 ttttttcata aaatgcttga atgtaagtgt tatacaatat tgttgttgtt aagtagaatt
    10201 agaaagataa ttaaaaatat gaccagaaaa aaattgttta taatattata aactaaaagt
    10261 atatcaaata atagaaatta acaagttaca aaaaaatatt ataaagaata atattttcta
    10321 aaaagtaaac tatagtaatg tggattatca ccttccaaca gtatataaaa tgagcgtaaa
    10381 aacggctatt tttgccttaa caacgatttt tttgtataca aatacgatat gctcattaat
    10441 tattggaatt tgtagtgctg tttaaattaa tgaaggtgta attatatgag tgatcatttt
    10501 gaaaaagttt gttgagaaga tgtgcttcta gtcatgtgat gggagaaaat aatttaactg
    10561 ttagagtgaa tagttaaatt attctggtta tatgaaaaaa gtagtttcta aaataatctt
    10621 gcagggatta acttaaagaa attgagagaa tagtttcttt gaaatttcta tatacaatga
    10681 gaagctgaaa tttactttta tttgatgact ggaaatagaa attaaatata ttgtattgtt
    10741 acattaaaga aaacttgtat ggaaaaatca gtacaatacc attatttaat gttcttcact
    10801 taaagcgcaa aaaatatcag tttattaaac tcgtatatag aacaaatata tgtagacggg
    10861 gcgaaacgat gagtgtaaaa aaaatgctat ttatggtaag tacaataatt gtattaacat
    10921 cccgattttg gggaattaat actagtttat ctatgcgata ttttattatg gcaatatggg
    10981 atttatattt tatgttaagc tatttttctt atcgtgagaa aacatataaa aaatacgtta
    11041 tcaagaataa cttttggttg actataatgc cgtttgtgat attttctatc tatactctaa
    11101 taatatgggg aattggttca aatgcagaat ttgaaaattt tataaagtta tgttccacgt
    11161 tgctttattt aattcttgca tatggttacg catgtacagc attttactta tttaaggcag
    11221 aaggaattga ttttattttt tggtcaggtg ttatttcata tatgagtggt tcagtttttt
    11281 atttaattgt atcttatggt ttaaatggtt taatttctta tataaaaagt cttataacag
    11341 gtgaaacaaa tactgcaaat tttgctatgg aggtacatga tttaactttt gcgatggggg
    11401 tttttttcct ttattacgta ttttttgaaa ataaaaatac aaaaaaacat aagataaaaa
    11461 ttatcgtatc tttaatttta attttcatgg gattgaagag aattgaactg ttagctttaa
    11521 gtggtgcaat tctagtgtat tatgttttat taaagtgggg aaaaaagatt caaatccgtg
    11581 cattagtgtg tactatttgt gcaactgtta tttcgttagt gtttatttac attatagata
    11641 caggaatttt ggcattgctt atgtcaaatt tgggcattac agatgacggt gcaaggcttt
    11701 cattttatct atattcatct aaattttatg aacttggttt aggatatgta ggaacaggat
    11761 ggacatggtt ttcaaaatac ttttttaatc tttatttatc gcactttagg ttaaatggtg
    11821 gaagaattgc agcaagccta cacagtgata tattaactat ttatatagaa gttggatgta
    11881 tagtttttat tatatggatg ttttggttat tttttgtgaa accgataaga ctaactaaaa
    11941 aatttggatt gaaaacaggg gagtgtgtat tattattaac tatatatatg tttatattat
    12001 atttgacgga taatacgctc acttatccag acactcaaat gatttttctc ttagtaccta
    12061 tgatagtttc gtgggttgat aatcaacaac gaatatcgga atagatagct aaagtatatt
    12121 ttaattatga atttataatt agttgtaaaa gttaatattt aacggacagg aagtagggtg
    12181 aaaaaatttg aaaaaaattt tagtgttagc aaatacatat tatcaaataa tagtagcaat
    12241 acaaatgaaa aatacaattt tttccgatga gtatgttgaa attattattt ctgatcattc
    12301 taaaaacact aaagaaattg cgaaaaaaat agaagaaaaa aaagtgtttg atggctgtca
    12361 ttatttagaa agcaaatctt ttgatgataa tattgggtat tttcaaaaga ttaaggactg
    12421 tcttcagatt tcttgtggta aatcaaatcg atatgcctat tatttgaaaa actgtaaaag
    12481 tgaatatttt gatgaattta tttgtttttc aatgggagag gtttggttgg aaggaatata
    12541 tgcttgctta tatcgaaata ataaaaatgt acaggtatca attttagaag aaggtatttt
    12601 aagctatgga gttgacatta ttccaacagc aagaacaaaa gctatcgcag tactcaatta
    12661 cttaaaaaaa aggactccac tatataacaa aagctataat ttttattgtt tttttcctaa
    12721 tatatataca ggaagagaga atacaataca aattccatta gttacagctg ggtcaagaac
    12781 cgcattgcaa ctttcggata tttttaaccc tatgatagat atttataaag aaaaaaaata
    12841 tatatttttt acgtctgttt atgattttga gggcggagaa cctgtcggag aatatgaatt
    12901 agtatgcaaa atagcagact tagtaggaaa agataatcta attgttaaga cgcatcctag
    12961 agatgtaaga acaatttata aagataatgg atttatcgag gataaaaatt catcaatacc
    13021 ttgggaggcg attcaattgt caggcgattt taacgataaa atatttatga caattaattc
    13081 aggaagtgtt atttcaggta gtacaatgtc tgcaaaacct gtacgcacgt attatatgta
    13141 taaattgtgt aacatagaag gaaatccgtc ttgcaaaaag aatgcgtatg atattgagcg
    13201 attgcttaag caaaaaacga tgaaaaacat tttaaagaat gtgaaaatag cagaaagctt
    13261 agatgatata ctatgagcaa aactaaatat ttaattaaaa atatgggaat attaacaata
    13321 agtaattttt cttcaaaaat tttagttttt ttgttagtcc ctttatatac aagtgtatta
    13381 tccacaacag aatatggcac atatgatttg acaatttcaa cagccacatt attgtttcca
    13441 attttaacct taaacattgt agatgctgtg atgcgctttt taatggataa agataaaaat
    13501 aaaaaaaata tagcatctat agcgattaaa gttatatttt taagcgtgat agtctttgga
    13561 tccgtaatgt atttgttaaa tattacaaaa ttatggcaag atgtttatgg attagaaaaa
    13621 tatatttttt tgtattatat atcctatgta tggaatcaat ttctaataca atttgctaaa
    13681 gggttagaaa aagttaaagc tatgggcata gcaggtatta tcagcacaat tgtaacaata
    13741 attgccaata ttttcttctt gcttattctg aaatggggat taattggttt tttcattgca
    13801 aatattttat cacagattat ttcagctact tatctgtcag tattagtgag aatatgggaa
    13861 tatatcgatt ttgaggctaa agatcctcag ctaaagagag aaatgctaaa ttactcgatt
    13921 ccattaattg caactgttgt tggatggtgg attaatagta cagctgatag gtatgtggtt
    13981 tcctttatag taggtgtctc ggcgaatggc ttattgtctg tggcatataa aatacctcaa
    14041 ataattaata ctttgcaggg aatatttata caggcctggc aaatttctgc aattaaagaa
    14101 tatggagata atgagactgc aaaattttat ggaaatacat ttgttatgat taatttgtta
    14161 atgtgcataa cctgttcaag tcttatcata ttaactagac cgttttcaca tattctttat
    14221 gcgaaagact tttatgaagc gtggaaatat gttccatttt tattaatagc taatgtttta
    14281 aattgtgcat caggtctgtt aggacctatc ttatcagcaa aaaaagattc taaatccatg
    14341 atgtggtctg caatcatagg ggcattagtt aatgtgatta tgagtgtagt ccttgtttat
    14401 aagatagggg ttcaaggtgc cacaatagcc actgttatat gttcatatgt aatatatgtt
    14461 gttcgtaaac gagctgtggg aaaagatatt tttataaagc attatcatat tgttgtggaa
    14521 tcttggggat tattgtttgt tcaggcaatc atagaaatat attttaaaaa ttatgtaata
    14581 gaaattataa ttatgattat tttaattatt ataaatatca gttatattaa gcagttgtgt
    14641 tatagaggaa gaaacattat ttcaatgatt aagagtcgag agcacaaacg gtagacgatg
    14701 ttatttttat aaaaagatat aatttattaa tggtcgataa ttatgaaagg aaaaatattc
    14761 ttaaaaaaaa gagtatagga tgtcgtatga aaatagtcgc tatagtacca atgaagttaa
    14821 ataacaaaag attgccacaa aaaaacacga aagcttttac caatggaaaa ccattgtgtt
    14881 attatatact ttcaacactt ttaaaagtaa aacagattga taaagtgtat gtctattgta
    14941 gtaacccaga tattaaagaa tttataccag aaggtgtaac atttttaaag agatctagtt
    15001 ccttagatca ggatacaacg agtattacac aggtattagc cggtttcaca aaagaagtag
    15061 aggctgatgt atatgtaatg acacacacaa cagcaccatt tattagcgaa aaatctattg
    15121 aaaaaggact agatgccgtg ctgacaggag aatatgattc tgcatttgct gcaaaaaaat
    15181 tgcaagattt cttatggaaa gacggtgaac catttaatta tgaattggac aatattccta
    15241 gaacacagga tttgccgcct ttatacgaag aaactagtgg attttatatt tataatcgca
    15301 atgtgatgac cgagttgcat agaagaattg ggaaaaaacc ttgcatagtt gaagtaggtg
    15361 agattgagtc agttgatatt gatgaagccg aggattttat gattgctgat gcgatttata
    15421 atcatcttat tttacaaggt agttaagaca gggggaaggt taggatgaac aatgtacaga
    15481 ttttagattg cacacttaga gatgggggct attgtaacaa ttgggaattt ggatttgata
    15541 atacaaaaaa aattatttct ggacttatag aatcaggaat tgagattata gaatgtgggt
    15601 ttctcacaaa taaaacagta tacaataaaa atgttacaaa atatacgacc ttagaagaat
    15661 tagcacagat aattcctgaa aaaagagaag gaaaattatt tgtagcaatg atgaactatg
    15721 gcgaatataa tatagaggat cttccagatt atgatggttc atctattgat ggaattagga
    15781 ttgcgtttca taaaaaaaat tgcaatgaag cgttgaaatt atgtcgtgag ataaagaaaa
    15841 aaggctactt agtttttgtt caagctatgg tatctctcaa ttatacagat gaagagtttt
    15901 tagcagtaat aaaaaatgtg aatcagttta aaccatacgc tttttatatt gttgatagtt
    15961 ttggaatgat gaaaggaaaa gatttaactc gtctttttta catgattgag cataatctag
    16021 aaaaagatat acagataggt tttcactcac ataataacat gcagcttgca tattctaatg
    16081 cacaaaaact tataaccgta caaacaaatc gaagcctgat tattgattct tcggtgtacg
    16141 gaatgggaag aggagcaggt aatcttaaca cagaactatt tgtagaatat ttgaatgata
    16201 atgcaggaaa aaaatatcaa ttaaaaccat tattatatat aattgatgaa atactaaata
    16261 gtttctatca gaagagttat tggggatatt cattaccaaa ctatatttca gcagttcata
    16321 atgctcatcc taattatgca agctatctgt catataagaa tactttaaca attgaagcaa
    16381 tgaatgaaat attcgaaatg atggatgaag aaaaaaaggt atcttatgat aaacaatata
    16441 tagaagattt atactacaaa tatatggaaa ctgggaaaat acaggaggaa tatatggaag
    16501 aactgagaaa atttctctca gacaaaaaaa ttctactgat tgcaccagga aaaagttctg
    16561 tagatgaggt agaaagaata aaagagtttg ttaccaaaga agaagtcgta ataattagtg
    16621 taaattttga atattctcat atagatatag attacgtatt tttaagtaat ttaagacgtt
    16681 ttcatgaatt accgaaagaa agcagaacta aatgtattgt tacatcaaat atacaagcat
    16741 cggatgtata tttacggacg agttataaaa agttgttatc tgaaagggaa gttgtaagag
    16801 acaatgcagg attaatggca attagatttt tagccgatat gaatgtggat gaaatattct
    16861 tagctggatt tgatggatat tcacataatg aagatgagaa ttatggtgag caatccatgg
    16921 aaattataac aaaatttgca ttattagatg caatgaacgt gcaaatgaga gatgaattgt
    16981 cagaattagc taaaaaagta aaggtgacat ttttaacgga tccacgttgg gttcgaattg
    17041 ataagtagta gtaataatgt ttttaaaatt ttgataaaga gatagtgaga gaataaaaat
    17101 gggtaaagtc ttaaataaaa aagaagaaaa atatttaagg gccgatgggg cgagatgaaa
    17161 ctctaatttt gaacttttaa gaatcatttc tatattgtgt attgttgctt accatgctaa
    17221 tttgcgttta aattataatg cagacggaat tatagtacat ggttcattaa ctgctaacca
    17281 gattttcttg aattatattg gtatttgggg tcagctagga gttaattgtt ttatatttat
    17341 ttcggcatat tttttaagtg agaaaagaaa cattcacttt gaaaatgttt tgggaattgt
    17401 attagaatgt attttttata gtgtattagt ttatggaatt ctttgtgcat gtggaataga
    17461 aacattttca ttgaacagct ttgtaaaaga aatattatca tttgctctag gtagatattg
    17521 gtttattaca tcctatttag cattgtatat tctaagtccg tatttaaata tcatgcttaa
    17581 caatctggaa aaacttcagt tgcaaaaaat aagtatgtta ttgtttatag gtgtatgctg
    17641 ttatcgtatg ttatttaaaa catctttgtt tggggattgt gctgttttaa ttgcactata
    17701 tgtcatatgt tatacactga aaaaaacgat aataatattt ttgagagaca cagaatcata
    17761 ggaacaattg tatgtataac agttatacca cttctcatat ccataggaat acttttcaaa
    17821 tttataccaa atgcaatggt taaccagatg gttcatattg gttctccatt gatggttata
    17881 gcaagtatat ttttatttta tgtatttaaa aatttttcat tttacagtaa gtatataaat
    17941 aaacttgcga gaaccagttt aggggtatat attttacatg aaaatcatta tttcattgat
    18001 ggtatgaagt ctagaggctt aatatgggat gggatatttg gattaggcaa aaggttttta
    18061 gatagggatt tttggatttg gtttataatt gcagttgtag ttgtgtgcat aatttgcatg
    18121 gctatcgatg ttgtaagaga aaaatttgaa agacagattt ttaaaattaa gagtgtaaag
    18181 aacctgtgta aacttatgaa tcatgttata aatatatacc cataattaat aaatgaggag
    18241 aaaagaagtg aaagttatat cattcggaga attattattg agacttgcag cacccggtta
    18301 ttcaaagtta tttcaaagag atagtttgga gactacattc tgcggagggg aagctaatgt
    18361 agcggtatcc ttagcaatat ttggatatca atcagaattt ataacaaagc ttccggattc
    18421 agatgttgga tatgcggcag ctaatgcttt gcgttatttt ggagtaaatg ttgataatat
    18481 tatatttgga gagggacgca tgggactgta ttatttagaa aaaggagcag ctcagagacc
    18541 atctaaagta atttatgaca gaaaattttc tgcaatttcg ttagctgata gtgatgaatt
    18601 taagtggaag gagatcctaa acgatgcaaa ttggtttcat tggacaggga taaatccagc
    18661 attgtctgag aatctctttg agacgtcctt agatgcatgt caggctgcca aaaaaagagg
    18721 tataacaatt tcttgtgatt taaattatcg atccaagctt tggacatcag aggaagcaaa
    18781 agaaaagatg gaacagatac taccattggt tgatatttgt atttgtaatg aagaagatgc
    18841 agaaaaagtg ctaggaatta aagctgagca tacaaatatt aatagtggag aattaaataa
    18901 agatggctat gtgcaggtgg ctagggagat tcacaagaag tttggatgta ggtatgtagc
    18961 tacaactctg cgtagaagtt attcggcaag tagaaatggt tggagtgcaa tgttatacga
    19021 agcagaaaaa gataaagcgt atttttccac agaatacaac atacaaattg ttgatcgcgt
    19081 tggtggtgga gacagctttt ctgctggtat aatatatgcg ttatgtgaaa atatgtccgg
    19141 acaaaaggct attgaatttg cgactgcatc tagttgttta aaacatacta tagaaggtga
    19201 ttttaatcga actacaattg aggatgtata taatttaatg aatagcggtg gaaatggtcg
    19261 cgtgttgcgt tagtcaacat ataaagataa atcacagtaa tttttatggt gattatctgt
    19321 cttagtagtg attagaataa cgtgaaaata aattgttgag cgtttatact gttttgaaaa
    19381 ataaatttaa catattgaaa aatacaaata tatacgtata ttataaagcg ccgattgtaa
    19441 aattaagcta gacaactaaa acagtcattt gtgctacact caaaatagtt ccgaccaaag
    19501 aattataagg agtgagtgca aataacctat acctatctta caacggatga acttgtaata
    19561 atagagtctt atttgaaaat taaccaatct gttgctaaaa ctgcgcattg cttgaatcgt
    19621 tcaagtcaaa cgatccataa agtatatctg ttcttcaagc aaagaaaatc agccttagaa
    19681 ta
//
LOCUS       DASHXG010000049        18916 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.050, whole genome shotgun sequence.
ACCESSION   DASHXG010000049 DASHXG010000000
VERSION     DASHXG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.050"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            165..401
                     /locus_tag="U2R59_002080"
     CDS             165..401
                     /locus_tag="U2R59_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966436.1"
                     /translation="MYWRVYKMKIASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIALQINEQQLAN"
     gene            425..766
                     /locus_tag="U2R59_002081"
     CDS             425..766
                     /locus_tag="U2R59_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966437.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDSRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(759..950)
                     /locus_tag="U2R59_002082"
     CDS             complement(759..950)
                     /locus_tag="U2R59_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HEM8966438.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSNNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDMTK"
     gene            1160..1807
                     /locus_tag="U2R59_002083"
     CDS             1160..1807
                     /locus_tag="U2R59_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966439.1"
                     /translation="MVGVVKFLGFTFDGYGTLGEWVGIILIVITIQQTSKYYWYSNSS
                     KIVSRITEGITKKDITVVGKYGFTITLLNEGKSETAIKFCGIIGKYNIFQRFIRKHWY
                     KYIYKYPVVKKLIEKYVDHEISYLNPTDLINQEFQNIGYLEKGLKIPIVNESLVTAMV
                     ANIKNSKKLEKRYKKCKKLKFSFLFLEYNGKEYYQDIYVLRGSNLYKDIKNKISV"
     gene            2067..2411
                     /locus_tag="U2R59_002084"
     CDS             2067..2411
                     /locus_tag="U2R59_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8966440.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            2416..2697
                     /locus_tag="U2R59_002085"
     CDS             2416..2697
                     /locus_tag="U2R59_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966441.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            2800..3114
                     /locus_tag="U2R59_002086"
     CDS             2800..3114
                     /locus_tag="U2R59_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEM8966442.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            3092..4786
                     /locus_tag="U2R59_002087"
     CDS             3092..4786
                     /locus_tag="U2R59_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEM8966443.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            4806..5984
                     /locus_tag="U2R59_002088"
     CDS             4806..5984
                     /locus_tag="U2R59_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEM8966444.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            5947..6633
                     /locus_tag="U2R59_002089"
     CDS             5947..6633
                     /locus_tag="U2R59_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEM8966445.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            6633..7793
                     /locus_tag="U2R59_002090"
     CDS             6633..7793
                     /locus_tag="U2R59_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEM8966446.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            7803..8678
                     /locus_tag="U2R59_002091"
     CDS             7803..8678
                     /locus_tag="U2R59_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966447.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            8675..8986
                     /locus_tag="U2R59_002092"
     CDS             8675..8986
                     /locus_tag="U2R59_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966448.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            8976..9329
                     /locus_tag="U2R59_002093"
     CDS             8976..9329
                     /locus_tag="U2R59_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEM8966449.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            9319..9720
                     /locus_tag="U2R59_002094"
     CDS             9319..9720
                     /locus_tag="U2R59_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966450.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            9713..10117
                     /locus_tag="U2R59_002095"
     CDS             9713..10117
                     /locus_tag="U2R59_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966451.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            10129..10734
                     /locus_tag="U2R59_002096"
     CDS             10129..10734
                     /locus_tag="U2R59_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966452.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            10754..11116
                     /locus_tag="U2R59_002097"
     CDS             10754..11116
                     /locus_tag="U2R59_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966453.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            11119..11301
                     /locus_tag="U2R59_002098"
     CDS             11119..11301
                     /locus_tag="U2R59_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966454.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            11318..14737
                     /locus_tag="U2R59_002099"
     CDS             11318..14737
                     /locus_tag="U2R59_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEM8966455.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            14788..15525
                     /locus_tag="U2R59_002100"
     CDS             14788..15525
                     /locus_tag="U2R59_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966456.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            15535..17826
                     /locus_tag="U2R59_002101"
     CDS             15535..17826
                     /locus_tag="U2R59_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEM8966457.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            17850..>18916
                     /locus_tag="U2R59_002102"
     CDS             17850..>18916
                     /locus_tag="U2R59_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966458.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGNYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTAT"
BASE COUNT         6757 a         2730 c         3932 g         5497 t
ORIGIN      
        1 attaggaaac aggatcgaca aaataaaatg taagggagga aatctccctc atcgtttaat
       61 taagcttcga taggcagcag cggaaatatt aagaataagg atgtgaattt caactccttc
      121 taaattgttc ttattatcta tcatccgttg ctgtctatta atttatgtat tggagggtat
      181 ataaaatgaa gatcgcttcc gaaaaaattg atcaactaac aattttagta aaccaaagaa
      241 tcgaagatat tatcaaagaa ttcgaaggtg aaaagattaa gaacataaag cttactttaa
      301 tggatcataa gttcgaatta aattcgacaa aaaggaagat cgttgagctt atagaagaag
      361 aaatagctct ccagatcaat gagcaacaat tagctaatta atttatgtat tggaggggaa
      421 atgaatggaa gtcgaacaaa taaagtatca aggtatggat cgggaacggt tgattgatat
      481 tattgagcaa caacgtttag aattgatcca aaaagaagct gtatgtaaag agtacaaaaa
      541 acatttggaa caagtaattg agtatcattc agtagaaaag tacagatcag tggtgcaaaa
      601 aaatagagca acgagtcctg attctcgtca agatgtatcg attagtatca agacgccagt
      661 atttaattct gttaaatcag aaaagctaga aagtatctca actgctttgg tagaaaaagc
      721 agctgaaatg aactccctag caaatgaagt tagtcgtctt atttagtcat atcgataact
      781 tgagagtctt tggtgattcc gttttttata gaattaatgg tttgttcagc ggaatattta
      841 gtcaagtatg tttcgctagt tgctactact tcattgttat tggacttaat aacgaagtaa
      901 tattggccat tagttgcttc tcttataaca aagtacaaat ttttcaccac ctataattta
      961 tttcagcgga ccactcgctg ataattaaaa ttataagcta tgtataaaat ttcacaatat
     1021 caatttgtcg ctgtggcgga aagggtagac gcaataaagg atgaatggga aaagtcaatg
     1081 agtaattatc tgaaatttac aagtcccctg tttagttatc taagattatt tgataatatt
     1141 atttctgagg tgatagaaaa tggtgggcgt agttaaattt cttgggttta catttgatgg
     1201 atatggtacg ttaggcgaat gggtaggtat tattttgata gtgattacaa ttcaacaaac
     1261 atcaaagtac tactggtatt ctaatagttc taaaattgta tcaagaataa ctgaaggaat
     1321 aaccaaaaaa gatattactg tcgtcggtaa atatgggttt actataactt tattaaatga
     1381 agggaaatct gaaaccgcaa taaagttttg cgggattata ggtaaatata acattttcca
     1441 acgttttatc agaaagcatt ggtacaaata tatttacaaa taccctgtag ttaaaaagct
     1501 tattgaaaaa tatgtggacc acgaaatatc ttatctcaat ccaacagacc ttattaatca
     1561 agaattccag aatattggat acttagaaaa aggtctaaaa ataccaattg taaatgaaag
     1621 tttagttact gcaatggtag ctaacataaa gaacagcaag aaattagaaa agagatataa
     1681 aaaatgtaaa aaattgaaat tttccttttt attcttagaa tataatggca aagaatatta
     1741 tcaagatatt tatgttttgc gaggctcgaa cttatataaa gacattaaaa ataagatttc
     1801 agtatgagat tttttaaaat tcgtagatca ctctttgagt ggtcttttta ttttgcgtaa
     1861 aggaggcacg acgatgtata gaccacaata cttagaacag aagcatgaag taatcactgt
     1921 gcaaaacggt aacggtgaga tagtacgaaa gtatagaaga ccaataaaga gcgatacata
     1981 taaacggaag gaaagcaatg aagttattcc attgtatggc aaaagaatag ctaagtatta
     2041 aataagattg cgaaaggaga tgggacatga ccgaggaatt ctatagatgg ttattacagt
     2101 tgataagaga agatcgtttg gttaagttct atcagtctcc taaatggcgc aggcttagag
     2161 agaaagcgat gaaacgagat cactatgaat gccaagagtg tagaagacta ggtaagtatc
     2221 atagagtaga gaacgttcat catataaagg aagtcaagga tagacctgac ttagctttag
     2281 atttagataa tcttatttgt ttatgtgttg aacatcataa tgaagttcat ggcagatatc
     2341 ttacagcgtt agataaacaa gagaagaaga tagaaagctt cgctaacttc gatgcaagtg
     2401 aaaggtggta agtgcatgat catcaatgac aatggcagag agtatgatac agaaaagatt
     2461 gaagagtatt catcttatac tcagggatta attaaacgtt tgatatacgt tcgctatgta
     2521 ggtattaggg atctgttatc agataactgt tgtagtaaat acaaagtgaa tcaagtaaga
     2581 gaagcgttga ataaagataa taacgtcgaa agaataaaaa atgtttttgg atatagtatt
     2641 gaagagatta attattacat tgacttcgct gaagctttca ttccgatggt gagataaccc
     2701 ccccttaaaa taaatcgcaa attttttggg ggtgatgaaa cggagggggc tgtcaggaaa
     2761 agagattttt tcgaacttta tcatgaaagg agggctaaaa tgtttaaaaa cgaattgtct
     2821 caaaatcgct acagagaaaa attacgccgc tctttaataa gccaattgga aagtcagaaa
     2881 acaaatattg agccattctt agataatgtt gatcgttata tcagtttatg ggaaacggcg
     2941 atatcactgg aagaagatat atccgagaac ggcattagac tggagaatgg taaaaagaat
     3001 gaatcagtag cgttgcttgt ttctgtcaac aaacaaatgg gattgatgtt ggataaactt
     3061 gccattactc ctgaattggt aggtgaagca aatgaatcaa ttcctgagtt ataagcatat
     3121 tgaaaattgg ttcaaagcta tagaagaagg cactatcaag gtatgcaaag agcaattatt
     3181 gctaaaaaat tatctagaag aaagagtctt tactagagaa gatatttact tcgataagca
     3241 gatggtagag gattcaatca atataccagc acaatacttt ccattcgaat taattccgtg
     3301 ggaaaaattt ctacaatgtt ttatttatgg tgttcgatgg aaaaaagata aaacactagt
     3361 gttcaataga tatctttcat taatgggacg tggtaatggt aaaactggtt ttgcttcttg
     3421 gaacaacttc tttctactaa ccgctaaaca cggtattaaa aattatgata ttgatatcta
     3481 tgccaataat gaaagccaag caaagactag ttttgatgat gtatttaaag taattaaaga
     3541 tcatcctgat ttagataaaa aagtatttaa agctacgaag gaagttattc aaaatatcgc
     3601 tacaaacagc aaacttcgtt ataacacggc aaatgctaga acaaaagatg ggaagcgacc
     3661 aggtgcaaac cgctttgatg aaattcacga aaatgaagat tattcaatga taaatgtggc
     3721 tacttctggt ggtggtaaaa ttcgagatta tagagaattt tatgatacaa ctaatggtca
     3781 tgttcgtggt ggtccgcttg atgacattat agaagaatca aaaatgattc tttctggaga
     3841 acttggaatt gacaaggatg gagcagaatt ttctagtttg tttccattta tttgtcgctt
     3901 ggataacgat aatgaagttg atgatcccga catgtgggaa aaagcttgtc caactattaa
     3961 ttacaatgca gatttaaaac ggaaaatgtt tcaagaatac tctcaaatgc aacgtaatgc
     4021 tggtttaaga cttacgttca tgaccaaacg aatgaacaga cctatggaag atacacgatt
     4081 tgctgttgct tcatatgatg atgttctgca tacgaaagaa aaagaatttc ctgaaaaaat
     4141 ggatgaagtg ataggaacag tcgattttgc tgatagacga gattttgcca gcgttgggtt
     4201 gctaggaaaa tacgataaag atgtttattt tacacaacat acttttatcc acgaatcagc
     4261 ccttcgatta caaaacatca aacgagaggt tatagatatt tctatagatc aaggaaaatc
     4321 acagatcgtt catggaaaaa atatagaagc tgattatatt gtaggttggt ttcttgaaat
     4381 gagtaataaa tattatatta aaaaaatcgc tatggatatg taccgtgcaa aaatattgaa
     4441 gcccgcttta gaagaagcag gttttactgt ggaaattgtt cgaagcggat ctgttacaca
     4501 tggtatgtta aaagatctgg ttgatgacct ttttattaat caacgtttat tttttggtga
     4561 cgatgcgatt atgcgttggt attgcatgaa tgtatatgaa gagcatattt ctaatggaaa
     4621 tatacgctat gaaaaaatag aacctgaaac tagaaaaacg gatggctttt tttcattcct
     4681 tcatggtttg aattttttag atgatattta tgattctgct cctgtaacag tcacaaatag
     4741 ctcagtagaa aatacaggaa ctggatttac tcctctagta ttctaacttg aaaggaggtg
     4801 agaaagtggg gatttttcaa aaggcggtag gatacttcac aaaaaaagca acggttcctt
     4861 tagaagaata cttttgtaaa ttgcaagttg attttgtgta tcgaaaattt gcgattgaaa
     4921 cttgtattga tttgattgca aatgcgatga gtaaagcgga attcaagtca tatgaagatg
     4981 gaaaaaataa aaagaatgat ctttactata ggctgaatgt agctcctaat aagaaaaata
     5041 atgcaacaga atttagaaaa aaactgatca ggagattaat attctacaat gaagtattga
     5101 tcgtttctcc gtctaataat tctagcgaaa tatttattgc ggatagttgg gatgtcacag
     5161 aatatgcatt gaaagatgat gtgttttctc aagtgcaaat taacaacata gtccttgata
     5221 gagaatttct agaaagtgat gttatctata taaaatacgc agatcaacaa attaggcaac
     5281 tagtcgatgc gtattatcaa gcgtatggga aactcatttc tagtgccatg aatgtttaca
     5341 agcgctctaa cgctcgtaga tacgtactga aagggaattt attccgaccg caagacaata
     5401 caacacaaga tcaaatcaat aaaatgatga catcacaatt taaggctttt atggaagctg
     5461 ataatgcagg tgcggtattt caattacaaa atgagtacac attagaagat ttcagcggaa
     5521 acttccaaag caattcaaga gatataaaaa acttaataga cgacatcttt gagatgacag
     5581 cagcagcgtt tcacgttccg aaaaacctac taaagggaga catgagtggg ttatcggatc
     5641 aagtggacgc ttttttaatg ttcgaaatca taccgattgc tgaacttatt caggatgcgt
     5701 ttaacgctag tctctatgaa gtagaagaat acttgtcagg gaattttgta cgtgtggata
     5761 caactatgat caagattact agcttcaaag atttggttga cgctattgat gtaggcatta
     5821 gaaatggagt atttacaatc aacgaaggaa gagagcgcgt tggaaatgat cgctctgata
     5881 aggcgatggc agatgaaata tttataacta aaaacaatca acaagtatcg aaaggaggtg
     5941 aggcgaatga cgacaatgaa aacatttcta gcagtaaaga atgaaggcgc agtaccgcaa
     6001 atttttattc agggatttat tggttctagt tggttctttg aagggaatac tgacaaggga
     6061 atcaaaaata ttttggatag tctaggtgat caagaagaaa ttgaagtagt aattaattca
     6121 aacggtggag acgtatttca agggattgct attgggaact tacttaagtc aaataaagca
     6181 aaagttaacg ttgtgattaa cggcttagcc gctagtgctg cttcaattat cgcaatggct
     6241 ggcgatacta taaaaatcta caacaatgca caattgatga ttcaccgcgc ttccacatac
     6301 ggagaaggaa atgtcgatga cttccgtacg attgctgacc aactggaatc aattgataaa
     6361 tcggtaaagg cttcatataa aacacgattc aatggcacag atgaagcatt gcaagaactt
     6421 cttgaaaaag aatcgtttat ggatgcagaa acagctttga gttatggatt ggtcgatgaa
     6481 attatcgatg cagaaaatag ctcaggtact gaagctaaaa aagaacaaag cgttgaagaa
     6541 attttgaatg acgttaaaga aaaaagagca gaaaaaattg ctgcatttac agcagcatta
     6601 aataaaacat ttggacaagg agatgtaaaa taatgacagt taaaaattta aaaggtgtaa
     6661 cagctgcaag cgaccaattg atgaaagctt ttaaagatgg taacgaagaa tcttttagcg
     6721 cagctatggt aagcttatct aaggaaattc aggataaaat tttagaagaa gcaacagcaa
     6781 aaaatcaaga tcaattagta ttaatgaacc gtggtcagcg tgtattaact acacaagaaa
     6841 caaaattcta taacgaagta gtgaaaaacg aaggttttgc aggggtcgaa gaattagtgc
     6901 cagctactgt atttgaacgt gtatttgaag atttagaaca atctcatcca ctattgcaaa
     6961 aaattacttt tgttaacaca actggtgtaa cagaatggat tgtgtcacgt ggagtcaatc
     7021 cagcatggtg gggtaaactt tgcgaagctg ttaaaaaagt tttagataat ggctttgatg
     7081 taattaacat gaagcagttc aagctatcag gttatattcc tgtatgtaag gcaatgcttg
     7141 atttaggtcc agtatggtta gatcgttatg tccgtactgt tttagtagaa tcattgagaa
     7201 ttgcattaga acaagcaatt gttgatggta ctggtaaaga tatgccagtc ggaatgatgc
     7261 gtgacatgag caaacaaact agcggagaat atgctgaaaa aaaagcagaa cctattacag
     7321 ctttagatgc tgtaactatg ggcggtttga tggcgcgact atcaaaattc aatatcgaag
     7381 gtgtgaatga tccgatttat cgtaatgtga atccttctga tgtggtccta attgtgaatc
     7441 caactgatta ctggtctaaa gtattcccag ctaagactgt actaactgct aatggagaat
     7501 acgtacaagt attgccagta ccagtttcag atttgcagtc aacggctgtg ccagaaggaa
     7561 aagcagttat tggggtagcc tcagattact tcatgggtgt aggatctaca ctaaaaattg
     7621 aagcttcaga tgaataccat tttgttgaag acgaacgcat ttatctagct aaacaatatg
     7681 caaacggtca acctaaacgt aacgatagtt tcattgtatt agatattagc gctttgggaa
     7741 ctactactac aactacaaaa ccaacaacca caacaactac aacacaagcg taggtgatca
     7801 gaatgaagta tattctttgt cagccggcaa tcaatcggtt taaatgggag cttgaagttt
     7861 gtttaactaa tctgaagaaa ctaggaatca aagatatcgt attgcttttc agcagacacg
     7921 atgatcagat tcctattttt tttgagaagg aatatggtgt tgaagttcat gtgtacgatg
     7981 atctgcggga cgacaaagag tatattcctt cgattaaacc atatttatgg tggaaatatt
     8041 tagaagaaga tcattcgcgt gaggacgacc gatatttcta tatcgattcg gatgtcattt
     8101 tcaataaaag aattaatttg cgcaaattgc cttctaaaga tgatgtttgg tattgtagcg
     8161 actgctgtag ttatctaagt cttgattata ttagaagctg tgaaaacgga gaaaatattc
     8221 taaaagatat ggcaaacatt gtaaatgtta cagtagaatc tttggaaact ataaacacta
     8281 attcaggagg cgcacagtgg gttattaacc gccctaaagc gaattattgg aaaaaggttt
     8341 atctggattc taatcggcta tatcgctacc ttagagggca aaaaacaaat ataaaaatct
     8401 ggacagccga gatgtgggca cagctttgga acatgatgta tttcaatatt ggtcctaaag
     8461 ttcacgagga attagacttt tgttttgcta ctgatccaat agaaaaagtt aaagaagtaa
     8521 aaatcttaca caatgctgga gtaacaacaa acgatgaaga tttatttttc aaagggagat
     8581 acgtgacttc tacgcctttt gatgaagatt tatcatttgt aaacaagaaa aaatgctctt
     8641 acgcatatgt taaagcaatt aaggcggtgg ttagatgacg cctgaacaag tgactgaaga
     8701 attgctaata gctgtgaagg ataatattta cgttacctgg aacgaagaag atgagtcaat
     8761 taaaaagatg atagctaaaa atgctgttta tcttcaaagt aaagtgagta caacactttc
     8821 tttttctcct gaaagcttag aatacggatt gctaatcgaa agatgtagat acgactggaa
     8881 tcgtgcttta gatgagtttg aacaaaattt cgctagtgag ttattaggtt tcattcaaca
     8941 ttatgcgcta caagaatata ttgcaggtga tgtgaatggc gaataatcgt agactcgaag
     9001 aaacattcaa cgatggttgg ttaaagattt tgacgcaaac taccaaaaga aatgaactag
     9061 gaaaaaagat tggtgtagaa gatacagaaa tcacttcttt aaaatttaga aatctttcca
     9121 tgagagatag tgatataaca gctatggatg cgatgggatc gaaattaact aagaaagtaa
     9181 agactccatt tcatccaatc gccaagaaat ttaataaaga tcaatatttt atcgtaatcg
     9241 atagtatgcg ttacaacgtt atctatgccg attacgataa tttttatatc tatttttatc
     9301 ttgaaagtgt gggtgaatat ggtgattgat aattctaaag aaaaagaacg tttaaataag
     9361 caaatttctg ctatcaaaac ttccttagaa gagcattttg gcctcaaact ctttcaagac
     9421 tccgtaggcg aggatgagct acctgatgat tttaattact tcattctcga aacaggagaa
     9481 atagaaatga tcactgagcc aaaatatagc gtgggtcaaa atctatatct aactttctat
     9541 tcagaaaata gagaagattt aacaggagat tcactagata ttatttcatt gattcaaaat
     9601 cgttcgattc gttttcagag aatggatccc aatcatttaa aactagagaa ccaagatcgc
     9661 tatatcgatc aattggtatt tacgtttaga cgattattga agagtgattg tcatggctaa
     9721 aaatagttgg gagctaaaaa taaatggaca tgatgaactt cttgtgcgga tggaacgcta
     9781 ttcaagcgag agcgaacgac tgattaacga agcattgaaa tcaaaaggtt cggctattgc
     9841 agtggatagg attacagaaa aaattcctgt ttctgaagca gatttaagaa gagggcacca
     9901 acacgcaaaa aatagtcgtc cacttaagac tcaatacatt aatttgggtt tcatcattag
     9961 acctacaaga aaatttgagt atttaaaata tcctgatttg gggataggta cttctaaaag
    10021 aaatcagccg gacgaattta tgagaagagg attaggtctt gcacttgatc caattacaga
    10081 acttctgatt cgtcaattcg ataaattaaa taaataggag gaacaacaat ggctaaaaca
    10141 acaacagtaa caacttttga caatataagt attaaaagaa tttcttttaa ttttaagaat
    10201 gcaacaaatg caatttcaac tgattgtaat ggacaattag atggcgaaac agaaatgcag
    10261 agaattgtaa aaaaatgcgg ttcaacagaa gtaaaatcga aatctaaacc aatcaatatg
    10321 acggtaacaa ttactgcaca tgtaccgatg gaagtttatc gacgcttcaa tgggttgaaa
    10381 caagatgaac gtattaaatc gggaatttac tcttatggtc ctgattccgt aggggaagat
    10441 ttctctcttg ctgcagagat cgtggatgat ttcgaagaaa aaaataagct gattggtatg
    10501 ttagcatgca cttcgaatac aggattaaca ttctctattg aaaatggtgc ggatgaagta
    10561 gctgcgttag aactagaaac aaaagttatg caagatgaat ttggtaaatt ttatcatgaa
    10621 gcaattgttg cagaacttga agaagactta acagatcaat ggatgacgaa tctatctgct
    10681 gatgtgatta aaaaaacttc agttgtgaca actacggcca ctcaatcaca gtaaaaaaaa
    10741 cggaggtagc gaaatgaacg aagattactc aaaaattgaa ctaaacgatg gaacaatttt
    10801 gaatttagaa cctaaactga atatcaagaa attattgatg atcaatagag attttaacac
    10861 agacgagttt gcaaaaatga ctgtgggaaa aggatccatg gatatttctg ttattcaagg
    10921 tgcaaaggct gtgtatattg cttaccgcca agcgaacatg actgattata tttcattcga
    10981 tgaatttatc gataaatggg attttgatat ggctactgcc agctatattt atcaattgat
    11041 gatgttcaaa caagcacgcg atgcttatca aaaagaattt gaaaaagcaa ataaggaaaa
    11101 aaagcttcaa aagtaaaaat gccaaagctc ttagttgaaa cgtgggtcga tgtctattcg
    11161 atgttgaccg acgttttttc tatgccttca gatttggttt taagcgatat ctgtttagat
    11221 gacattttgc aaatggctta caacaagagt gcttatgaag gatggaaaaa ctatgcaata
    11281 aaccaatccc agaaaaacta aagaaaggag gtaaaaaatg gctaaaaaga gaacagaagc
    11341 agaagtaaca ttcatagcta acgatgacgg attgaaatct acgttaaaag aaatcagtgc
    11401 tgaattaact aaaaatagag cagaattaaa actagaacaa gctcaattac aacagactgg
    11461 ttctgaatca gacaagttag gaagtaaatt atcttcttta gaaaagcagt atgaattaca
    11521 aagtcaaaaa gttgaagtaa ctagccaacg tttagccaat gccaaaaaat attatggaga
    11581 aaattccacc gaagttcaga aacttgagag agaactgatt aaccaacaaa cagcgcaaca
    11641 acgtttgtca aacgaaattg ataaaacgag taatgcacta gctcaagcaa aaggcgaaat
    11701 acagacgtac gagtctacaa tgcaacagtt ggatagtgaa caaaaaaatg ttcaagctag
    11761 tgcttctctg attgaatccg aatacaaaaa atggcaagca actgctggtc aatcagcttc
    11821 tgaatccgag aaattagcga aagcccaaga atatgtttct caacaatctg aaaatgcaga
    11881 gaaaacgata gatatcctga gacgacagtt agaagctaca cagtctgagt ttggcgctac
    11941 atccacagaa gcaatgcaga tggaggcgaa gcttaatgat gctgaacgtg aatttgaaga
    12001 gttaggacaa gctgctaaaa atgtagatac aactaacttg gacgatatcg gaagcaaaat
    12061 agatatgaat aatctaatgg aagcttctga cgttttaagc gacattggcg ataagcttac
    12121 agaattaggg aaacaagcag tggactctgc taatagtgta ggtagttccc agagtaaaat
    12181 acaagctaat tttggtttga ctaaacaaga ggctgaagaa ttaacgaatg tagccagaga
    12241 catttattat aaaggttttg gagaatcgtt agatcagtcc acagatgcat tgattttggt
    12301 aaagcgtaat ttaggcgatt taaataatca agatttacaa aatatcacgg aacaagctat
    12361 ggtcctagaa aacaccatgg gcgctgatat ggatgaaacg ttacgtggtg taaatggctt
    12421 aatggtcaat ttcggcttga gcgctcaaga tgcaatggat ttaatggttt cgggtactca
    12481 aaacggttta gataaaacgc acgaattagg cgacaatatg gcagaatata gccaattatg
    12541 gagtcaaatg ggatattcag ctgatgaaac gttcggaatg cttcaaaatg gtttagatgc
    12601 gggtgcttat aaccttgata aagtcaatga cttagttaag gaaatgggaa tatcgttaac
    12661 agatggtcga tttgagcaaa acatggatat gtttagtgaa agtactagaa aagcttttga
    12721 agagtggaaa aatggcggag gaacacaaaa agacgttatt aattccatga ttcaagattt
    12781 tagcaatatg gatggtcaat acgaccaatt aaataaagct tctacaattt ggtctgcact
    12841 tggcgaagat aacgcgatga aagttgtcca atctttgact gatgttaacc atacatttga
    12901 tgatgttagt ggatctgcac aaaaaatgaa tgaagattct actactccgt tacaagaatt
    12961 aaacggaaaa atagctgaat taaaggattc attagctcct ataggcaaca caatcataga
    13021 tgcactcgaa ccagtaattg attttctagg aaagatggct gatgcgttta ataatcttcc
    13081 acaaccagta caggattatg ccgtagcgat tggcggattg actgctgcat ttactttatt
    13141 aatgccaata atagttggct tcatggctct aggtggtcct actacattaa taataggagc
    13201 agttattact gttattgctg gagttatagc aattataaaa aactggggcg caattactga
    13261 ctggtttaag ggaatatgga gtaaattcac tgattggttg ggtggtactt gggaaagtat
    13321 aaaagaaggt gcctcatcag tttgggatgg agttaaagaa acctggtctg gatttgtaga
    13381 ttgggttcaa gatatttggc aaggagtttc tgattggttt ggagagctat ggagcggatt
    13441 agttgaagga gcttccaaca tctggcaagg agtccaagag acttggcaag cattcgttga
    13501 ttgggtttca aatatttgga acggagtcaa agaagtatgg tcgattattt gggcagacat
    13561 tgtaggaatt gttcaaatac catggacctt aataacgtca ttgattcaag ccggtattaa
    13621 tattatcgtg ggtatttttg atgtagctgg acagttatta ggcgcagctt ggcaagctgt
    13681 ttggacacct atttctgatt tccttaaaaa cacttgggat actatgacac aatgggtaag
    13741 catcgcttgg aatggaattg taactacatt ccatactata tttgatccag tagtggcatg
    13801 gtggaatggt atatggacag ctattagtac tacggcttca aatatttgga attcaattag
    13861 tgcaacagct tctagtattt ggaacagtat caagaataca atcactagct tggtacaagc
    13921 agctgctaca gtaattcaaa atatttggtc aactgtatct agttggttag gtggaatttg
    13981 gaattcaatc agctctacag catcaaatat ctggaatagc gtgactagta gtataagcaa
    14041 tgctataaac gcagctaaaa gtgccattca aagtgtttgg aatagtatat cttcgtggat
    14101 cagcggaatt tggaacggta tcaaaaacac tgctttgaat ctttggaatg gaattacaag
    14161 cactattagc tctaaagtaa acgatggaaa aaatgcaatt tcaagcggtt ggtccaatct
    14221 aacaggtatt gtttccgaca tattcaataa tgttaaaagt acaattgcta acatttggga
    14281 aggtatcaaa aagactgtta gcgctccaat tgattggatc agagataaaa tcagtagtat
    14341 ctttgataat ttgaatattt ctataccaca tattccgtta ccacatttta aattgagcgg
    14401 agaattcaat ccattgaagg ggaaaatccc aacgttgggt gttgattggt atgcgaaagg
    14461 tagtgtgttt aattctccga atattatcgg tgtcggcgaa gcaggacctg aagcagtttt
    14521 acctttgaaa agatctgtgc tgcaagaaat tggtgatcgt atcttgagta gcacatcagt
    14581 ttcatctagg gcacaaacga ttcaacctgt gaataactac gaattcaatt tcacaattga
    14641 tggtaacgca gatgaggtta ctatgaagca aacaactcaa caaatcattg atagcattac
    14701 aaaagttcaa aatgataatg cttcggcatg gcgttaaaca ggagagtatt tctcctgttt
    14761 ttttagtatt aaaaaggatg tgaaaaaatg actgattgta tacattctat aatcgatgga
    14821 tttcctgatt atttgcataa attggcttta gctgaaagac caaccatacc ttctccaaaa
    14881 agacagagag ttgaaacttc tgttttagga aggttaggtg gcttagtaca agattactcg
    14941 tttgaagaca tgtcgtttac attgcactat aactatttag aggatgtgga agaccatcaa
    15001 gcgttcaagc aatcgtttta tatcatgcgt cattggttaa attatgcaaa gaaattagaa
    15061 ttctctgatg atcccaacgt ctattatgtt atccagacta tcgatattgg ggatgcagaa
    15121 aacgatattg ttgaatgggg agagttcgat gtaaatatta ctgcgaaacc attcgcaaga
    15181 gttcaagaag atgtacctat aaccgtagat aaaccacagt catttaactt gctgaataat
    15241 agtttagaag aaagttttcc aaagattatc atcactcctt cagctacttc atgccagttc
    15301 atcttaaatg attatgtgtt tagttttgaa ggcttagtag taggaactga cgtagtcatt
    15361 gatagtgatt tgatgctttg ctacgaagag caatcggacg gagatatttt agatcggtcc
    15421 aacaaaatga agaccatgca atatccgaca ttgcaagtgg atattaatta ttttaattgt
    15481 actggtttga gcaaaataca aatttatcgt aatgggttaa ggtaggtgaa atagatgatc
    15541 gataatttaa taactattta cgataaaaac gacgcgaata atttagctga acatttatat
    15601 gatacgcaag gtttaggcgc tttgtcagac tggttaacag ctactgttag caataaatta
    15661 aacggagccg agatatttca gggtacttat ccaataagcg gaactaatgc agatttgatt
    15721 gtagaaggac gtattattca gtgttatgta gatgaaaatc gagcaaaaca gcgtctacgg
    15781 atttattatg caaagacttc tgtaataggc aatacgatag aagtaaaagc tgaacctatt
    15841 ttcaatgata taagaaaatc ggtgttgaat aaatatgaca gtggaacaga aaagatcact
    15901 gctagtcagg catggcaaaa cgcaaaaact ttagcgaaac cagttattcc ttcacagttt
    15961 tctttctcgt cattagtaga tacgcttgct aatgtgaaga tagaaaaggc gaatttttta
    16021 gaattctttg gtggaaaaga gggatctatt ctagatcgat ttcatgggga atttctaaaa
    16081 gataataaca cattacgtca tgaaaaaagg ctaggcacgg atcataaaat caaagcgatt
    16141 tatactaaaa acttaactgg tcttgactta gagattgatg ctcaaagtgt tttagttgga
    16201 gtttatccat tcattagcag ctcttcagaa ggagaagacg agatcactct accagaagaa
    16261 gttattttca cggattacgt ggatgattat cctgctggat atgtttcttt tgttgatttt
    16321 aaagacaaag cgactgatgt agccacatta agggaagctg ctaaagactg gttgaaaaca
    16381 aacatagata aacaaaaacc acaagtgagt ggttcgattg aattagtacc attgaggcat
    16441 caaagaggct atgaaaaatt tgttgatcta gaaaaagttt cgatgggtga cggagtagat
    16501 gtgtatcatc cacagttaaa agtgaatatg tcagcgagaa ttgtggaata tacgtttaat
    16561 gttctaacca attcatacga taaattagtt gtaggaaacg tcaaaacaaa cttcttagaa
    16621 aacacagaga ataatgtcag caatttgatt aatgatgcca ttgatcaatt gaaaaacggt
    16681 ggcgaaatca gtgatttact caatgatatt gtagatcatc aaactgatat gattactggt
    16741 caaaatggtg gttatgtttt attagatcct aaagaagcgc ctagtcgtat tttgattatg
    16801 gacacaccag ataagaatac cgcaaggaat gttttacaaa tcaacaatgc tggtattggt
    16861 ttttctaaaa ctggcattaa tggaacatat gaaacggcat ggacgttaga tggcggattc
    16921 aatgcctcgt ttattacggc tggtgaaata gtaggaatta ctattagagg tactacatta
    16981 attagtgatg gtgctgatta tagaacaagt attgctaatg gcaaaatgac ttggtactca
    17041 aaaaaagtta acaaagatat tatggagcta gaagcacgtg attatgtaag tgctgatgcc
    17101 ggtattgtat catacaccat gaaaactggt ggtggtttca tgattagaaa tccacagggt
    17161 aacttggttt ttagtacgtg ggataatggt aataacagac cgtttctatc ttttggtgcg
    17221 cccaatttca ggtatagcaa tgctagttat gtaacttctg gcgacggtag ttctttaagc
    17281 attaatggta gtgcgggtaa ctcatgggaa tttaaggtag ctggtaggac tatgaaattt
    17341 actagtgatg gtatgctaac gttaccaggt tgtttttttg gttcatggga agatgggaaa
    17401 cttgctaggt ttgaacaatc aacggtacaa gtatataaag attttactgt tagaggtact
    17461 aaaaactcaa ctgtaccaac agaacattat ggacaacgac tattgaacgc ttatgaaact
    17521 ccagaatatt atttcgctga ttatggggaa gccgttacag gtgacaatgg taaagttcgt
    17581 gttgatattg accccatgtt tgctgaaaca gtaaatctaa gtcggtatat gacacatgtg
    17641 acacctacag aactagtttt gtgtgctgtt actcatgaag atattgacca tttcatcatt
    17701 gaaactagta agccaaacgt attagttaga tggaatttag tggcacaccg tctagggtat
    17761 gaagatatta gattaaaaga ggatacagca tatgatagca cagtgcttga ccaaaaacgt
    17821 ttttaaaacg aagacaagga ggtatataaa tggctagcag tttatataat ttggctttag
    17881 atttcagcaa agaattaaac tacaccaaag ctattatggc tcgtcaaggt gataaaggga
    17941 ttacggtgac ggttaaaccg tttctaaatg gcttgcagat ggatacgagt ggcggaacat
    18001 ttactttaaa aggaacaaca ccatctaacc gttacgtaga taatgttgca actagtgtaa
    18061 ctagtgaaga agtcacgttt tctcttgatg gcacatttat gagtgaagca ggatattata
    18121 aacactgcta cgtagaatat agaaaagaca atcaaatttt aacaacgcaa gatatcattt
    18181 ttttctcact aggagtgtct gacatttcgc aaggccaagc cgatgaatat gtttcgcaat
    18241 tagaagagtt gattcgaaag tacaacgaaa cttttgatgc ttttatggct gaaatcaaag
    18301 gtagagtgga tagcttaaat caacagatta ctgatttaac tggtcaagct aaaacgctac
    18361 aagacaagtt agatgctctg aaagaagaaa tttctaagtt aggtaactta caagtgatgt
    18421 acagtaacag catcgacttc gggaattatg attatagtgg gaatccgaat ttaatgtcca
    18481 aactaaaatc gagcgatttt aacgttggtt accacgggtc actaacttcg gataacgaaa
    18541 agctacattt tacttctgat ggtacaggaa gcattattat gtttacgcgt attaatacac
    18601 ctcagcttgc tagtgggaaa acctatactc tgagtgcgaa agttcgattt gatgaaggaa
    18661 ctacaggagc tattgataaa ttacgtttgg tgtatcgtac atcaccagga gaaaagatat
    18721 tattggaagc aaatagtaca aatattacaa cagatgatgt agggaaagaa ataacaatca
    18781 aaggtacagc taacgttaat tatcaaatca caaatttaga tcgattttat atgagtatta
    18841 gctttgttga cagggataaa ataaatggcg gatttaagtt gtacgacatc aaaatcgaag
    18901 aaggctcaac agccac
//
LOCUS       DASHXG010000050        18726 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.051, whole genome shotgun sequence.
ACCESSION   DASHXG010000050 DASHXG010000000
VERSION     DASHXG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.051"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..577)
                     /locus_tag="U2R59_002103"
     CDS             complement(<1..577)
                     /locus_tag="U2R59_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8966459.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
     gene            719..1651
                     /gene="pfkB"
                     /locus_tag="U2R59_002104"
     CDS             719..1651
                     /gene="pfkB"
                     /locus_tag="U2R59_002104"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEM8966460.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            1633..3096
                     /locus_tag="U2R59_002105"
     CDS             1633..3096
                     /locus_tag="U2R59_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8966461.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            3093..3551
                     /locus_tag="U2R59_002106"
     CDS             3093..3551
                     /locus_tag="U2R59_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEM8966462.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            3548..4522
                     /gene="lacD"
                     /locus_tag="U2R59_002107"
     CDS             3548..4522
                     /gene="lacD"
                     /locus_tag="U2R59_002107"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEM8966463.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            4963..5691
                     /locus_tag="U2R59_002108"
     CDS             4963..5691
                     /locus_tag="U2R59_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966464.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            5709..6905
                     /locus_tag="U2R59_002109"
     CDS             5709..6905
                     /locus_tag="U2R59_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8966465.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            6898..7893
                     /gene="lacD"
                     /locus_tag="U2R59_002110"
     CDS             6898..7893
                     /gene="lacD"
                     /locus_tag="U2R59_002110"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEM8966466.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            7890..8831
                     /locus_tag="U2R59_002111"
     CDS             7890..8831
                     /locus_tag="U2R59_002111"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HEM8966467.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            9007..9486
                     /locus_tag="U2R59_002112"
                     /pseudo
     CDS             9007..9486
                     /locus_tag="U2R59_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            9499..10389
                     /locus_tag="U2R59_002113"
     CDS             9499..10389
                     /locus_tag="U2R59_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8966468.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            10376..11185
                     /locus_tag="U2R59_002114"
     CDS             10376..11185
                     /locus_tag="U2R59_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8966469.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            11199..11600
                     /locus_tag="U2R59_002115"
     CDS             11199..11600
                     /locus_tag="U2R59_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8966470.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="U2R59_002116"
     CDS             complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="U2R59_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEM8966471.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(13156..13431)
                     /locus_tag="U2R59_002117"
     CDS             complement(13156..13431)
                     /locus_tag="U2R59_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEM8966472.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            13539..14303
                     /locus_tag="U2R59_002118"
     CDS             13539..14303
                     /locus_tag="U2R59_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEM8966473.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            14426..14929
                     /locus_tag="U2R59_002119"
     CDS             14426..14929
                     /locus_tag="U2R59_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8966474.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            15338..15979
                     /locus_tag="U2R59_002120"
     CDS             15338..15979
                     /locus_tag="U2R59_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HEM8966475.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            16149..17417
                     /locus_tag="U2R59_002121"
     CDS             16149..17417
                     /locus_tag="U2R59_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEM8966476.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(17444..18643)
                     /locus_tag="U2R59_002122"
     CDS             complement(17444..18643)
                     /locus_tag="U2R59_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEM8966477.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
BASE COUNT         5981 a         3117 c         4066 g         5562 t
ORIGIN      
        1 atttaaaaaa ttgaaaaata aagacataaa tcttattttt gatgttttta tttgttttct
       61 caccgttcaa agaaacaaaa ataacgctgt ctttcttagt tagtttccga ctgatgcttt
      121 tgataatttc tggatcagta tgcatctgac aattttttcc cgttaattga agttttacca
      181 gcatttcttg gccaatcatt tctgaaaatc ctcgggcaaa gacaaaaacc cggtcagcaa
      241 atttgattct ttgtattgca tcttcaatgt tcccgatttc caacatattg attgtacgta
      301 ccacttcttg ttcatttttt agaatggctc ggcggattcc tttgtctact ttatctaaaa
      361 atgaaaaatt gatgttcttg ttttctcctt cttttagatg atgcttaaac gaagtaaacc
      421 cttcatagcc tttctttttc attgtccgca caatggtggc tgttgagaca tttgcttgtt
      481 cacttagttt cacgatggaa tagttaggga tctctaggat gaggtgttcg ataaagttcc
      541 agaggtactg ctctgtttca cttaatttgt gattcatatt ctttccttct ttcaccaaaa
      601 gttagttaaa aaaagcacga cgagtttata aatgtaaagg ttttctttgt gttgggacga
      661 ttaagaaaac attttctatt tcgcgtattt cataatagaa tcaaggaggt cgttggttat
      721 gtctatctac acatgcacga tgaatttggc aattgatcta tttattgaaa cagatgagat
      781 gcatcctttt atggtaaacc gcacaaaaga ggatgacatt caggcaaacg gaaaaggggt
      841 gaatgtgtca ctagtattaa agatgctaga tttcccaagt acggcattag gtttttctgc
      901 tgggttcaca ggaaagtata tagaagacta tttacagcag aaacaaatcc aaacagagtt
      961 tattgaagtg cctggtatga cgcgtatcaa tgtatttaca caagtcaatc aaacgggaga
     1021 agaatacaaa ttagtgaatc aaggacctga aataccgcag acagctgttc ataatttttt
     1081 aaatcaaata agagcattac aagcagggga ttatctttgt gtttctggga gtttaccaag
     1141 agggctgtct ccaaaggttt taatagaaat cagtcggatt tgtttgatta ttgatagtag
     1201 tgatcaagaa gtcatggatt gtttacccta tcgaccgttt ttgctgaaac caaatgagga
     1261 agaactttct tcttggttcg gacgaaaaat ggttacagat gaagattact ttgtttatgg
     1321 acaacgacta gtagagtcag gcgcagaaaa tgttttgtta tccctcggtg agaaaggagc
     1381 gattcttttt acgaaagaca gggtgattcg aggaaactcg ccaaaaggaa aagttgtcaa
     1441 tacagcatgt gcaggtgatg ccatgttagg cactttttta gcaggataca tgaatcgacg
     1501 atcgcttgat gaaacgttac gtaaaagcat agcagcaggc agctctactg cttttcgtaa
     1561 aggactgact gattttttgg atgtggagga attaagtaaa caaatcaaaa tcaaggaaga
     1621 gaggttcgaa agatgggaaa atatcaacta attgcagcaa ccggttgtcc gacaggaatt
     1681 gcgcacacct acatggcgca agaggcatta gagcaagcag ctaggaaaaa aggcatcacg
     1741 atcaaagtgg agacccatgg acaaattggg atcgagaatg aattaacggc tgaagaaatc
     1801 aaacaggcag atgctgtcat tattgccgca gacaaagatg tccattcaga aagatttgtg
     1861 ggaaaacgag tcattgatgt ttctgtcagt acaggaatca aggatgcaca acggctgatt
     1921 gacgaagcat tggcaggaaa aggtactgtc ttagcagata atgaagctgc tgatacttta
     1981 gaaccagaag cgataagtgg tgctaatttt ggtcgtagca tctataaaaa tttgatgaac
     2041 ggtgtctctc atatgttgcc tttcgtggta gctggcggag tattgattgc tatttcattt
     2101 gccgtttggg gaatctattc ttctgatcca gatcatgcac aatacaatgc tacagcggca
     2161 atggtaaaag cagttgacga tgcagcaatg ggaatgatgg ttccagtttt agcagcttat
     2221 attgcagaag ggatcgcgaa acgtccaggg ttagtcgttg gatttgttgg tggaatcgta
     2281 gccatgaatg gcggtactgg atttttagga ggtattttag ctgggttctt agcaggttat
     2341 tttatcttat ttttgcaaaa gctactgata attttaccta aacaactaga tggcttgaag
     2401 gcaatcgtct tatatccagt tattggtgta gcatttattg gcatcgtgat gtctttgctg
     2461 gcaggtccaa tgaaggctat aaatgaagga atgatgagct ttttagctgg atttgaatat
     2521 tcgaatccac ttgttcttgg cgtgattgtt ggctgtatgt gtgcgtttga tatgggagga
     2581 ccggttaata aggcggcata tgtaacagga acagctcttt tgacacaagg aaacacgact
     2641 tttatggctg gtgcgtcagc agcttgcatt gcaccaccgt tgattactgg ttttgctact
     2701 ttattgtttg gtaaatattt tgatactaat gatcgtaatg caggtttggt taattttatt
     2761 ttaggatcaa ctcatattac ggaaggagct attccgtttg ctgcgaaaga cccgatccga
     2821 gtattaccaa cgatgatgtt aggctcatca attgctgctg tcttgaccta tctgtttggt
     2881 gtccaagtac cagccccaca tggcggtttt ttagtgttac ctgtagtgac gggaaaaatc
     2941 caatgggtta cagcgattct tattggttcg atcgttggtg gagtgatact aggtttgatc
     3001 caaaagaaaa gagtaactga taaagacaag aagagggata ataaagcaac aaatcgtaca
     3061 gttatcgaag aaggaagagc aggaggttta tcatgacaat cattcatgaa gagaacattt
     3121 ttttacaaca gccattagat aatcaagaag aagcatttaa gtttttagca aagcaaacat
     3181 tctgtttagg aatcgctcat gacgaaaaag aagtatatca aaaacttctg gaaagagaaa
     3241 aagaaggtac tacaggaata atgtcaggtt ttgctatccc tcatgcgaag tctcaaacaa
     3301 tcaatgaacc tagtttgatt atcgtcacac tgaaaaaagg aattgaatgg aacagtttag
     3361 atagacagtc agttgatttt atttttgcgt tatttatccc agattcagaa gcaggaacga
     3421 ctcatttgaa attattgtct ctcgttgcac gatcattgat gcgaaaagag gttacagaac
     3481 agttgagagc tgcaaaatca aaaatagaaa tagctacaat attaactaaa gaaataggtg
     3541 aagatatatg aagaaaatga gtatagaaaa acaggaacgt ttgaagcgat tgacggatga
     3601 agctggaatt attagcgcgc tagctatcga ccaacgtggt gctttgaaga aaatgatcaa
     3661 ccaatataaa gaagctacat cagaagatat catccaattt aaacagatgg tttctcagta
     3721 cctgactccg tatgcttccg ctattttact cgatccagaa tatggtctgc ctgcagcagc
     3781 gcttcgagag aaagaatgtg gtttgttgct agcttatgaa aaaaccggct atgatgcgaa
     3841 aatgccaggc cgactaccag atttactgaa tagttggtca gtgaaaaggt taaaagaagt
     3901 gggtgcggat gcttgtaaat ttttattgta ctatgacgtt gatgaaccag tagagattaa
     3961 tgtgcaaaaa caaatagtta tagaacggat tggttcagaa tgcgaagcag aaggcatacc
     4021 tttcttttta gagctccttt cttacgatgc aactattggc gatccgtctt ctcttgacta
     4081 tgcaaaagta aaaccgcata aagtgattga agccatgcga gaattttcaa aagaacgtta
     4141 tcaagtggat gtattgaaag tagaagtacc agtgaatatg agatttgtgg aaggatatgg
     4201 gcaagatact tgttatagtc aagcagaggc atccgcgtat ttctatgaac aatcgaaagt
     4261 gactgaacaa ccgtttattt ttttaagtgc gggagtcagc gctgcactat ttcaagatac
     4321 attgcgtttt gcaaaacaat caggttcgac attcaatggt gtcttatgtg ggcgagcaac
     4381 atgggcgaag ggagtagcac cttttgttac cgaaggcgaa gaaaaagcga gtagttggat
     4441 gttagaagaa ggaaaacaaa atattaaaga attaagtaca ctattagaag aaacagcaac
     4501 ttctatttat gttaacaagt aagagaaagg attgtctgag tgacagattc aaaaaataat
     4561 tagttattta aaaaaatgtt tgtcaaattt tatagaaaaa aagtataaaa ctgcaaaagt
     4621 tatctaaaac taataataac atttgtcatt aataagctat ttttagttgt tgtaaatgat
     4681 attggaagta ataaaacgat agttgtagga atatcatagg gattaatgtg gatcacgctg
     4741 ctcgataagt tagaccattt tgacggatcg cttatgtggt tcgtcttttt ttctgttctt
     4801 ttattggtaa ctggtatttt tgaggtatct ttgtctattc aagatataaa gctttaaaga
     4861 gctgttataa tagctttttt ggtctaaaaa acctttgaca aatgattaat aattcactat
     4921 tcttgtgttg tggttataac cagtaaagaa gaggtgattt ttatggagag ctcaaataaa
     4981 ggaaaatcat tgtattatca actagttgat ttattgaagg atcgtatcga aacacagatg
     5041 actccgcatg ataagctgtt atctgaaaga gaactttgtc aacactatgg ggtgagtcgt
     5101 accaccgtac gtctggcttt acaggaattg gaaaatcaag gttatattta ccgaagacat
     5161 ggaaaaggta cctatgtctc tgatttgtct gataagtcat cgaacttagc tggagcatat
     5221 agctttacag aagaaatgcg cgaaataggg cgcgtcccta agacggtcat tttagaattt
     5281 agacaaatgg aagctaataa gagaattgct aagaatttga acatccattt aggtgaaact
     5341 gtatttaaac ttaaaagatt gcgtttggca gatgaagagc cattgatggt tgagcgttct
     5401 tatctaccgg cgaaactatt tatgggactt gatttgccgt tacttgaaag taaaccgttg
     5461 tatgatgtgt tttcacagga ttatgaacaa caagttcaat tagctgatga agagttttat
     5521 gcaagtatcg tgcaaaaaaa agatgctgtt gtgctacgaa tcgctgatgg cgctcccgtc
     5581 ttacatctga cgaggataac ctataacgtg aaaaatgaga ttatcgaata tacagatagt
     5641 gtagcaagag cggaccagtt tcattataaa attcggcata tccgaaaatg attgagaggg
     5701 agaacaacat gtttgagcta tcgaagaaca aattaaaaca aataggtgca gcaatcacga
     5761 cacaagaaat aaaacaacaa ccagatctct ggaaagaaac aatcgataga ttgatgcaaa
     5821 gccaagaaaa tttagctcta ttttttgatc aaataaaaaa agaagcaaac ggaagaagaa
     5881 tacgtgttat ttttacgggt gcaggaacgt ctcaatatat tggggatacg ctcttaccct
     5941 atctaaatga acatggagac aatcagtttt ttatcttcca cagttttggc acgacagata
     6001 ttgtagcttc accaaaagaa tttttgtttc caaatgaacc gactttatta gtttcatttg
     6061 ctcgcagtgg caacagtcca gaaagtgtag cggctgtgca aattgcaaat gaacaagttg
     6121 aaacattgtt tcatttgacg attacttgtg ctaaagaggg gatgttggca aaaaacgcac
     6181 aggatgataa acagaattat ctgttattga tgccagagag agcaaacgat gcaggttttg
     6241 ctatgacagg aagttttacg tgtatgttat tgagtgcttt atggatcttt gatcaaacag
     6301 caatggagaa aaaagaaaga tatcttgaac aattagttaa aatcggtcaa gatcttcttt
     6361 caagagatca agaaattcaa aagttattac ctgatttttt tgaacggatc gcttatctgg
     6421 gttcaggaag tttggcaggt gcgacaagag aagcacaatt aaaaatttta gaattaacag
     6481 caggtaaagt tgctacaatt tttgattctt cgatggggtt tcgtcatgga ccaaagtctt
     6541 ttttaaatag cgagacactc gttgtaggtt ttgtgagcaa tcaaccatat acgcgaaatt
     6601 atgacttaga tattttagag gaaataaaag aagatcgggt cactgccaat gtcattgcga
     6661 ttgcgcaacc gggtactatt gatttctcag gtatgactgt gctattggaa gactcggtga
     6721 gtaaattgcc cgatgcctat cttgcattag cgatgattat gactgcacaa atcattgcac
     6781 tctatacttc aatcaaagta gctaataaac cagatacacc atctccaaca ggcacggtca
     6841 atcgagtagt caagggcgtc attattcata agtatgaaac cgaaggagaa atgacagatg
     6901 aatgaagaaa aaaatagggc aatggagaga ctatcaacaa aagatgggat tattagtgca
     6961 ttagcgatcg atcagcgtgg tgctctaaaa aaaatgatca aatcgttggg aaaagagcca
     7021 agtgaagacc aaatcagtga attcaaagaa ctagtatcag ctgagctgac accctatgct
     7081 tctgctattt tattggatcc ggaatatgga ttgccagcag caaaagtcag agcaaaagag
     7141 acggggttat tgttagctta tgagaaaacc ggctatgacg caactacgcc tggtcgtcta
     7201 cctgatttat tagcggattg gtcttctctc agattgaaag aacagcaagc ggatgcagta
     7261 aaattcttac tttactacga tgttgatgaa gcacccgaaa tcaatcattt gaagcatgtg
     7321 ttcatcgaac gtttaggtag tgagtgcgaa ggagaaaatc gtcccttcta tttggagtta
     7381 gtttcttatg acgcacaaat aagcgatagt tcttctccag agtatgcgaa agtcaagccc
     7441 cacaaagtta ttgagatgat gaaagaattt tctgatccaa aatataaagt tgatgtgttg
     7501 aaagtagaag taccagtcaa tatgaattat gtgaatggct attccacagg tgaatttatt
     7561 cacagcaaag aagaggctgc tgccttcttt aaggagcaaa gtgaagcgac tccattacca
     7621 ttcatttttt tgagtggggg tgtttcaaca gaattatttc aacaaacact gatttttgct
     7681 catgaatcgg gttccacctt caatggtgta ttgtgtggac gtgcgacatg gaaagatggg
     7741 gtcaaagcat acgtcgaaaa tggaaaagac ggagctattc attggttaag aacaaatggg
     7801 agagaaaaca tcgagacttt aaataaagta ataaatgaaa ccgctacccc ttggttcaat
     7861 aaaacaaaaa gcaaaaaggt gaagatgaaa tgattacgac agttaccttg aatccttcca
     7921 tcgatatcgc gtatacaatt gaagaattaa acctcgacaa agtcaatcga gttgaaacag
     7981 tcaataaaac agcgggagga aaaggagtga atgtggcgag ggttctaaat ttattaggag
     8041 aagaggtgat agctactggt ttaataggtg gccagcacgg tgaatatcta aagaaccagc
     8101 tagatcagtt agggatcatg catcagtttg ttccaattaa aggagagaca agggattcta
     8161 ttgctatcct gcatagttcg agacaaacag agcttttgga acgaggcccc ttcataacaa
     8221 agaaagaaca acagacattt accgatcatt tcgagcagct cctcgaaata tcagatatta
     8281 tgacgatctc aggtagttta ccccaaggat gccctcttga ttactataag caattggttg
     8341 ctttagctga taaaaaaggg aaagacatat tactagatac ttctggtaaa tttttgcttg
     8401 aagtattgga aggtaaggag aagccactac ttatcaagcc caatctggaa gaattaggag
     8461 aactgattgg ccaacgtatc tgttcttcga ttcaattaga aaaaattcag tccttattag
     8521 ctcatccaat atttgaagga gtgccatggg ttgttgtttc tttaggagag agaggtgctg
     8581 tggcaaaagt tgctcagtgt ttttacgaag tcattattcc taaaatatca gttgttaatc
     8641 ctgttggttc aggtgacgcg acccttgcag gatcggccca tgcgttatca aaaaggcaat
     8701 caatcgaaga gattctcgca ttttctatgg cttgtggtat ggcaaacgcg caacaagaga
     8761 aaactggctg gatcgaccct atgaaagtta cgatgttgat gaaacacatt caagttaaga
     8821 aaatcaaatg aacttaaata taaaagaaag cgttttcttt agttgggaag gaatttgttc
     8881 ttagcttaaa aatgaaatat aagaaagaaa aaatgaaaac gttatctttg aaacagaagg
     8941 gatatttgat gatgtcacag ttttaattga acaataaata gaaaaaatag ataaggagaa
     9001 tgcatgatgg caattattgg tgtaagaatc gatggacgtt tgatacatgg ataagtagca
     9061 aatctttgga caacgaaact gaatattagt cgaatcatgg tcgtggatga tgaggtagcc
     9121 acaaacacaa ttgaaaaaag tggattgaag ttagcgactc cagcaggggt aaaattaagc
     9181 attttgccaa tcgaaaaagc agcaacaaat attttagctg gcaaatatga ctctcaacga
     9241 gtattgatcg tagcaaaaaa gccagatcga atcttatctt tagtagaaaa aggagttcct
     9301 atcaaagaag taaatgtggg gaatatgtca caaacgaatg aaacacggtc cattacaaaa
     9361 tcaatcaatg tggtagatgc agatatcgaa gtatttaaaa aattagatca gcttggtata
     9421 catttaattg ctcaaatggt accaaacgat aaagcagaag actttatgaa tcttttaatc
     9481 aaataggagg aatgatccat ggatattcaa tggtggcaga tcttattatt aacattatat
     9541 gcaggttatc aaattttaga tgaattacag atctattctt caatgagtgc gccagtgttt
     9601 gcagggttat atgcaggttt agtaatgggt gatttaaacg caggtttgat tattggtggc
     9661 agtatgcagt tgacagtttt aggagtgggg acgtttggag gcgcatcaaa aatagatgcc
     9721 aactctggga cgattttagc aactgccttc tcgatttctc ttggaatgaa tccagaacaa
     9781 gcgattgctg ctattgcagt gcctgtagca agcttaatga tccaattgga tattttagct
     9841 agattcgcta acacatactt tgcccatcgt attgaccgtc acgtagaaga catgaattat
     9901 caagcaatcg aacgcaattt cttaatggga gctttacctt ggtcgctctc tcgtatgatt
     9961 cctgtatttt tagctttagc atttggtggt ggattagttg aaaatgttgt ttctgtttta
    10021 aacgggaatc taaaatggct aggcgatgga ctttcagtag caggagctgt tttaccagct
    10081 gttgggtttg ccattcttct gcgctattta ccagtaaaaa aacatctatc ttatcttatt
    10141 ttaggattta cgatcacggc attattagca acgttattct ctaatgttca attattagga
    10201 acaagtgtgg caagcgttgt taaagatctt ccggcaactt tcaattcgct gccgatgctt
    10261 gctgtagcat tgattggtct agcactagca atgatcagtt ataagaatga tcaaaacaaa
    10321 gaccatcaac cattagctag tgagccatca cattctgttg agggggaaat cgaagatgac
    10381 gaaatctaat tacaaattaa caaaagaaga ttttaagcaa atcaatcgaa gaagtttgtt
    10441 cacttttcaa ttaggttgga actatgagag aatgcagggt tctggctatt tatatactat
    10501 cttgccacaa ctaagaaaaa tatatggaga caatacacca gaattaaaag agatgatgaa
    10561 aacacatacg caatttttta atacttctaa tttttttaat acaatcatta ctgggattga
    10621 tcttgcaatg gaagaaaaag agggaattgc ttcaaaggaa accgtatcgg ggctgaaagc
    10681 tggattgatg ggttcctttg cagcgattgg agattccgta tttgctgctt tgattccaac
    10741 gatttttggg gctttggcgg cgaatatggc aactgatgga aatccgatag gtgtgtttat
    10801 atggattttt gctcagatcg ttgtcatggt ttttcgttgg aagcaacttg aatttgcata
    10861 caaagaagga atttccttag ttactactat gcaatctcgc ttaactgcat taacggacgc
    10921 agccacttta ttaggggtat tcatggtagg ggcattagtt gcgacaatga tcaatgttaa
    10981 attttcatgg gcaccaacga ttggcgatgt gacattgaat atgcaaaact atatcgatat
    11041 gatcttacct aaaattttac ctgctgggat cgtcggtggt gtttattggt tattaggaaa
    11101 gaaaaacatg actcctactc gagcgatttt tatcgtatta attgtgtgtg ttgctttatc
    11161 tgcattgggt gtgatttcga aataagggag agcgaaaaat gagtagacaa ttggtattga
    11221 ttagtcacgg aaaattttgt gaggaattga aaaaaagtac agaaatgatc atggggcctc
    11281 aagaggatat ctacacgtta cctttattac cagaagatgg cactgaaaca tacaaacaaa
    11341 agtttctcac tgtcacagat tcgttaaatg attttgtggt actatgcgat cttttaggtg
    11401 gtacacctgc aaatatcatt tctaaactaa taatggaagg acaacagatt actctttatg
    11461 ctgggatgaa tcttccgatg gtcattgaat ttatcaactc acaaatgatt ggttcagagc
    11521 ccgagtttgt tcgtgcagga tgtgaaagca ttgtctctgt caacgaatta attaatggaa
    11581 tagcagaaga ggaagagtaa caaaaaagat gagggcttag ctctcatctt ttttgtccta
    11641 tgtttttatt tccgcttctg ctgctttcct gcgttgcggc ctttgttgtt tgtactgttt
    11701 tttggttgtt tgatttgttt tgttgcttgt ttgttgttag ctggctttgc tgattctgtc
    11761 acgtcttttc ttggagtgac gacttgtttt ggcgggtttt gtttcaactc ttctgccact
    11821 tgtgctttca aacgtggttt catcataacg tttgtgatga atgtttgcag acagctgaac
    11881 acaccaccga ctacccagta aagtgtaaca ccggctggcg cactgatcga catgaagacg
    11941 atcatagcag gagagacgat tagcatcgta cgcatcgtct ttttctgttc ttcaggaata
    12001 ccgatcgttg agatgtatcc ttgaagcaga taggcgaccc ctgcaatgac aacaagtacc
    12061 atacttggtg agcctaaatc gatgccgtag aaagatgatt cccgaatacc ttctgtataa
    12121 cgtgccgtaa agtacaaggc agagaagatc ggcatttgga tcaatagagg cagacagccg
    12181 attccgccgg tcatactcaa tccgttttcg cggtatactt gctgcatttc tgcttgtgct
    12241 gccatttgtt cttcacgtgt tgttgcagct ttcaattttt gttgggctgc ttcaacttgt
    12301 ggttttaacg cttgcatttt ttcagattgg atcattgttt ttttcgattg actaatacct
    12361 agtggcaaga tgatgatacg gacgatcaca gtcattgcaa taactgccca gccataagac
    12421 caattgaaat tctcaactag atatgtaatc gcttggccca taggatggac gagtactcga
    12481 taaacgattc ccgaagtgtc agggtttccg tttgaatcca tccgcacaca gccagataaa
    12541 aagagcagga tactgacaag tccggatccc aataaccagt ttttccattt attcatagaa
    12601 tacttcctct tctataattt ttacacaaac ttaactatac taaaaaagcg catggaattc
    12661 aatcaacttc atagaaattt catataaata ttcgttcttt tacgtagcga aaaattttga
    12721 aaaaaagaca aaaaatcaag aaagaaatac ttggaaagaa aagagtgatt ccaagtgttt
    12781 ctttcttatt taaaaaacta aaaacttttt tgttctgtct ggaaaatatg ggttaagcaa
    12841 atttattgca agttatagat cagctttttt actacctatc tttaatactt gaggcaaagc
    12901 gtctcaaaaa caaccttatc gacggtgttc aaaagtcagt ttctcggtat taagtcaaat
    12961 tttatgcaaa aatgtggaaa gccattttca caaaattctc cttactactc aaaactaagc
    13021 gactttctca caaccttatt gacggtgttc aaaagcttgc atctacggca ttaagtccag
    13081 cctgttgaaa aatatggaga gctatttttc acaacctgtc cttaatgctt gatgcagacc
    13141 agctttttca caaccttatc ccaccacatc aaatttcttt cgttcctcaa tcatcgggtc
    13201 ttcttggaca tccacatact gcactcgtcc acttgggctc ggagatttct tgacttcttc
    13261 aataaatttc tggatgatgt cgtcattgcc gattgcttcg atcgtgactg agccgtcatc
    13321 ttcgtttttt accgttccag tcacgcctag ttgatcagcg accatcttgg tcatgtagcg
    13381 aaatcctacg ccttggacgc gtccttggac gttcatttta actttgcgca tgttcgtcac
    13441 ctttctttcc tattttataa attaatgata ccgatttttt taggatgaaa caagctcaag
    13501 cacctattcc atgatataat catggggagg tgaggaatgt gaaagagatc caatcagcaa
    13561 aaaatccaag aatcaaagaa ttaaaaaaac tacataaaaa gaaatatcgg gaagaaaagg
    13621 aagaatatct tttggaaggg ttccatctga ttgaagaagc tgcgtcgtct gatgcagaaa
    13681 taaaagaact ttttgtgaca cagcgaggca tgaaagaatg gggagactgg ctggccgcaa
    13741 acaaagagat ttctactttt ctagtttcgg atgaggtcat ggatgctgta tcggatctac
    13801 ctacaccaca aggaatctta gcagtgatgg cgttaacggc tgaaggcacg ccagattttt
    13861 caggaggatg gctgttatta gataatgtac aagatcctgg aaatgtaggg acgatgatcc
    13921 gtacggcaga tgcatttgat atggctggtg ttttattagg caaaggaacg gcagatattt
    13981 atagtacaaa ggtgctgcgc agcatgcagg gaagcaatta tcatttgcct gtgttgcaaa
    14041 aagatttgac agaagtgatt cctttaatga aagacaaagg gtttacagtg tatggcacag
    14101 aattaaatga agaagcacac gccttagaca aagtagaaaa atcagataac ttcgcaataa
    14161 tcatggggaa cgaaggtcag ggggtaagtc aggaaatctt gtctttgact gatcagaacg
    14221 tatatatccc gatgaaagga aatgcggaat cgttgaatgt tggggttgcg gcagggattg
    14281 ttctttatca tttttcttta tgattaagga actattaagc tttggctatt ttatccaagg
    14341 cgactagaat aatccgaaca ctggtggtat acttagatca atttcagaag aaaatgaaat
    14401 tcaaaaaggt ggcagatcga taattatgac agaaaaatgg cgtgaagacg aagaatatat
    14461 gtcttatgta gaagatcttt tagaaacaga agcagtgaaa aaattagcga attacacaca
    14521 gcatgttcat tccactcgtt tggagcattc catcagtgtt tcttactata gttatctgct
    14581 cgcaaaaaaa tggggtggca atgctaaagc aacagcgcgt gctggacttt tgcatgatct
    14641 gttctactat gattggcgta cgacgaaatt tgatgaaggc acacatgcgt atatccatcc
    14701 aagaatcgct gtaaagaatg cagaaaagat caccgatttg tcggatcttg agcgagatat
    14761 cattttgaag cacatgtggg gcgcaacgat tgcaccgcct aagtacaaag aaggatatat
    14821 cgtaacattc gtagacaaat actgcgcagt caaagaagcc gctcagccta tgtcagcaag
    14881 tatgcgtaag agatggcaac gttacttcgg aaaagaatcc tcgatttaac aggtaaaacc
    14941 aataatagac catattgagg ttgtgacaga agtgggtcag cttcaagaaa taagaaggaa
    15001 tttacgaaaa ttgcttctca aatttttgtg aaattccggc ttattttttg aagaagctac
    15061 ttctggaaca ccgtttgttt gtagaaaggg actttgacac gacttttgtc acagtccttt
    15121 ttctgtttgc agttgactat ctgctcaaga tacggtttac ttttatttat cgaatgaatc
    15181 atgtacatag aagaatgaac attaaagggg gtgatgataa gatgcaaaac gtatcttatt
    15241 taaaagagtc cgggatcttc aggtaacaca tactttgcag aagatcactt ttttctacaa
    15301 agtatgcact ttggttagaa gaaaggactt taaaatcatg gaacaaacaa tgaaaccata
    15361 tcaatatttt tttataaaaa gagaagtaga gcagttatta aatgcgtact catctgtcaa
    15421 tgactcaaaa acggtacaaa cggttcaggc tctagcagct gaaaagattc gcgatgtatt
    15481 aggttacgaa ccatcagaaa tcgatacgtt tttaacgaca gttttagatg taaaactgac
    15541 aaaaacgcaa gcagaacgag cattggagga gctgaagcaa atcgtccagc cgtttatgca
    15601 gccgagcaaa ccacaaatcg agaaattatt ccgaaaagtg aaaaaactca aacaacccgc
    15661 ttggaatgaa atcgacttgc aagcacatac gtacatcggt tggaatgatc cagggacgca
    15721 aaaaaaattc atggtttatt acgaagatgg aaaattaaaa gggatcagcg gtactttatc
    15781 accaacgatt aataagggaa tctgtgcgat ctgtcagaaa acatcgaatg tctcgctctt
    15841 tctttctaca acgaaagccg gttctgatgg cacgtatacg aaaaagggga attatatttg
    15901 tcatgatagt gatcaatgta atcaacagtt aacgaaattg gctcctttct atgaatttgc
    15961 tgaacgtgta aagaaataac gataatttta ttgtttttta cagaaaaata tgctatcttt
    16021 taatggaagt gaataggtga tggtgttcgc ctttaaatgc taacgtaaga tagctaatga
    16081 cgcctactaa agtctggggc cagccccttt ctttagtagg cgttttttta tttgaggagg
    16141 aattttttat ggaaaaacaa ttaccgagtc cagtgcgtat tttgatgtac atgttgaagt
    16201 ggctggtggt cacagcgatt ctcggagtat tcatggggag cttgtctgct tttttcttaa
    16261 atagcctgac gttcgtgaca gatatccgac tagcacatcc ttggctactt tatctattgc
    16321 cagtcagcgg cgcgcttttt gcttatcttt atgcgtatca tggcggtctt tctagtcgtg
    16381 ggaataactt agtgatcgat caagggaatg gaggagaaga gaagatccct ttgcggctca
    16441 ttccattgac cttgtttggg accatcacta cccatttatt tgggggatct gttggtcgtg
    16501 aaggaacagc agttcaaatg gggggagcat tagctgataa tatagcgcat ttattccgat
    16561 tggataaagc agaacgggag attttggtta tcagtggaat cagtgcgggt tttagttctg
    16621 tatttggcac acctttagct ggaacattat ttggattaga agtgttggca atcggtaaag
    16681 tccgaacaga agcaatattt cctagcttct ttgctgcgct ttttgcaaat ttcatgacag
    16741 aaagctatgg tgtttctcat ctacattacc aaatgggtgt gattcctgaa tggagtatgt
    16801 tgctgttctt caaagttttt gttgctggga ttgcttttgg tttgattggt tgggtattca
    16861 gccgttcgat cgtcttttta aaagcgcggt atgcgcaatg gattcctcat cctgtttggc
    16921 gaaatacgat aggtggagca gtagttgtag ccgcagcgtt gattttgcaa acacaacgtt
    16981 accttgggtt gagtcttccg ttactgcagg aatcatttaa tggacaggca catgcttatg
    17041 attttattgg gaaattattc ttcacggtct tgtctttagg tgcggggtac caagggggag
    17101 aagtgacacc actatttgag attggtgcaa cgcttggcgc agtactagcg cctttgctcc
    17161 atgtttctgt tccttttctt gctggattag gttttatcgg ggtattttct ggtgcgacaa
    17221 atacaccgat tgcctgtttt gtgatgggaa tcgaattatt tggttcacaa gctgctgctt
    17281 acttctttat gatctgcttg atcagcttta tgtgttcagg aaacagcggt atttattctg
    17341 cacagcaagt agccgtcaaa aaaggaatac tattcttgcc aatcgtcaag agaataaaag
    17401 aaaaaaacaa ggtgtgacat atgttttgtc acaccttgtt tttttagaaa agtaaagtga
    17461 tcagtgataa gaatgcggaa cctgcgaaaa gcaatccgca aatgatcata tgtctttttt
    17521 tgttcatcat caagatggcg atgtattctc ttaaaaacgc gttaggcaag taatagaaag
    17581 ctgtttttgc cccaatgcca tttgccttca gtttcgcttg tcgtgcatag agaccagctc
    17641 tgaaaatgtg gtaattgttg gaactgaaga tcgcgcgata gggacctttc atttgctgat
    17701 ccatgatttc ctttgaatag cgcatattct ccaaagtggt tgtcgaattg gtttcgacaa
    17761 gaatatctct ttcaggaatt ccttgttcca tggcatattg tttcatcgcc attgcttctg
    17821 gtactttttc gtctgctccc tgtccacccg acattaatag gataggcgga tttaatgtcg
    17881 cacggctttg tgcccaataa aaagcaatcg ccttattgat tcgcttggca agaagaggag
    17941 aaactgtttc tccattgatc aacccggcgc ctaacacaac gatgaagtct tggttgtatc
    18001 gagggcggtt gaactgatac aagaatgaga cagtcaaaaa gttgtagaat acgataaata
    18061 gatagatcaa gatcaatggg atgcagaaaa acaaagcatt tatccattgt ggtaaatatt
    18121 ttaacaagaa aaagtcaaaa acaagaaaca atgtaagaaa aatggctagt atcaacgtta
    18181 aaagattagc taatgaatgc gactctctac gtaaaactgt gacaccgttc caaaaaagaa
    18241 aaacgatcaa tccataaatg ccgaatagaa agacaagcag taacgggatc gtgatcaagg
    18301 caatcagtcc gccaagaaaa atattttgtg tttcgtatag caagacaaac aagtagatac
    18361 caaaactaat gaggaaaata ttgaataaaa gaccattcaa cagccttcgc ttttctgaaa
    18421 aataggaaaa ggcaaagata ctgaaaaaca ctaagggaat caaaaaataa aaggtcgaat
    18481 aaaaaatttc caacacgaca aaataagtca agattaccgc aaacgtccat gtactgctgt
    18541 aaaagaacaa ggaaggatcc tttttctgtt ttcgccaata aacgatggag aataccccaa
    18601 taagatagag aaccaaaaaa atcagatctc tggttagatt cataaattca actccttttt
    18661 cttatacagt ataacgaaaa tagatgaaaa aagctgttat ttaaactaga aaaagcaaaa
    18721 aaacat
//
LOCUS       DASHXG010000051        18575 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.052, whole genome shotgun sequence.
ACCESSION   DASHXG010000051 DASHXG010000000
VERSION     DASHXG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.052"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(367..933)
                     /locus_tag="U2R59_002123"
     CDS             complement(367..933)
                     /locus_tag="U2R59_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEM8966478.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(933..1889)
                     /locus_tag="U2R59_002124"
     CDS             complement(933..1889)
                     /locus_tag="U2R59_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEM8966479.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(1889..2545)
                     /locus_tag="U2R59_002125"
     CDS             complement(1889..2545)
                     /locus_tag="U2R59_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEM8966480.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            2915..4933
                     /locus_tag="U2R59_002126"
     CDS             2915..4933
                     /locus_tag="U2R59_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEM8966481.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5003..5209
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5360..7774
                     /locus_tag="U2R59_002127"
     CDS             5360..7774
                     /locus_tag="U2R59_002127"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEM8966482.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8122..9675
                     /locus_tag="U2R59_002128"
     CDS             8122..9675
                     /locus_tag="U2R59_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEM8966483.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10056..11840)
                     /locus_tag="U2R59_002129"
     CDS             complement(10056..11840)
                     /locus_tag="U2R59_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966484.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11855..13576)
                     /locus_tag="U2R59_002130"
     CDS             complement(11855..13576)
                     /locus_tag="U2R59_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966485.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13676..14437
                     /locus_tag="U2R59_002131"
     CDS             13676..14437
                     /locus_tag="U2R59_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8966486.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15404..15672
                     /locus_tag="U2R59_002132"
                     /pseudo
     CDS             15404..15672
                     /locus_tag="U2R59_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16344..>18575
                     /locus_tag="U2R59_002133"
     CDS             16344..>18575
                     /locus_tag="U2R59_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966487.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6104 a         3299 c         3745 g         5427 t
ORIGIN      
        1 ggggcataat ttgactgata ttaagttagc tattgatata tgaatgacat acaaaaatat
       61 aaaatctttt aaaaatgctt atatatcaat gtttttgcca ttcttttata tatctgttat
      121 atgtcaaaaa aatgtgttca atttcaattt gtatttgaat aaagaggttg tgaaaaagct
      181 gtcctgcatc aagtaataag aacagccaat caaaaacagc ttctcatgtt tttgatttgg
      241 ttggacttat taccgcagat ataagctttt gagcaccgtg aataaagagg ttatgaaatc
      301 aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca tatcatttat gttttgcgtt
      361 ttttatttat ctttttttct caatacaata taaaataggc ggctggttct tttggttgat
      421 aaaccgataa ttcagcacat tatatgtttc ctgtggcagt ttggaacaaa aagaatcaac
      481 catatccagt tctttttctc caccttcatg accatagtag acgacaagga tcaatcgtcc
      541 gcgaggcaca agtcgtttca atatttcttc catagctgtg cgtgtagtct ctggcatagt
      601 gatgattgct ttatcacttt ttgggagata ccctagattg aaaatccctg ctttgagatt
      661 ttgttgttca gctatcactt ctcctaacgt ttcgtggcct tgtagaaaca atgagacacg
      721 ttcttctaac tgacgctgtt ctagcctttc acgagtagca tcgattgctt gttgctggat
      781 atcaaaacta tagacatgac cagtttttcc gatgtgttct gctagaaaaa ccgtatcgtg
      841 gccattgccc atcgttgcat ctacgacgtg atcccctggt tgcaagattt cttgcagtaa
      901 tgtatggctg aaatgcaaag cagtttgcaa catcagacgc tcaccttttt ccgtacatca
      961 tattttcctt ggaagctatc tctgcgaaga agttcttcat caattgcatt caagacttcc
     1021 cattttttca agctccacat tggtccaatc aaggaatccc acggcgcatc ccctgtcaaa
     1081 cgatggatga tgatctcttt tggtatcatt tccagctggt cgcaaatgac attgacatag
     1141 tcaggacggc tcattaattg aaggcgacct tcatgatagt cccgcaacat tctcgttttg
     1201 cgcatcagat gcatcaaatg gagcttgatt ccttggatat ctgaatctaa aatggtgcgt
     1261 ctgacatttt ctttcatcat ttctaaactt tcgcctggta atccgttgat caaatgcgta
     1321 caaacacgga tattatgttt gcgtaattta gccacgccat ctaaataagt ttgataatca
     1381 tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg tttgcaatcc aagttctacc
     1441 cataaataca tccgctcgtt cagttcagca aggtaatcaa ctacttcatc tggcagacaa
     1501 tccggtcgtg taccgactga taatcctacg acacctggta aattgactac ttgctcaaat
     1561 cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa aattttggaa ataaacgatg
     1621 tattgttgga catgaggcca tttttgatgc atcatgtcga tttctttctg gaattggatt
     1681 ggaagagggt cttcaggtgc aacgatcatg tctcccgaac cagatacact gcaaaaagta
     1741 caaccgccat gggcaacagt cccatctcga ttcggacagt caaatcctcc atcgatcggc
     1801 accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt aattccaaga atgatatctt
     1861 ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt ctttctgtaa gagttatcta
     1921 tttgttttct tttttctcta tacactggat aagtcaggca cagccaagaa agactgagta
     1981 agtaaccgcc gatgatatca gtaggaaaat gaacgcccag ataaatgcgg cttatcccga
     2041 cacttactat aataaacatc atcagcaatt gaagcaatgt gcgtaaggtt cttttttgaa
     2101 caaaagctgg aagcagaaat agtaaagaac cgtaaagaat catactgcct gctgcatgtc
     2161 cactagggaa actgtaactt gtttcaacta ctaagtgcgc caatgaagga cgctctcgca
     2221 tgaaaaatag tttgatcacc gggttgatga ttccagcaat tacaataaat ccagaaacga
     2281 accaaaatgt ttctgccctt tttttcttat accacatcca taaagccgca caagcaaata
     2341 aaatgatgac ggtaagagga ttaccgaatt tagtcataaa gagttggtag ctgttcagat
     2401 caggataaga agctctgaca atgcctgtaa accactgatc gaaaccagaa agccacgaca
     2461 gatggaactt tacgatccag cccaaaatga aaaacaggac aagaaagaag ctaccagcca
     2521 cctgaaatga tgttttatat ttcatacaat tcctcctttg aagcaatgac ttattatagc
     2581 atttttggtc cagcgaaaaa aacggtaaag agataaaacc aatgtatgat tcctctttga
     2641 ataaccaata ttcttataaa aaaaataact gtaatcggaa agacattttt tggtaatgca
     2701 aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat ccttttaaac aagaacgtag
     2761 acgtaggaag aacttgaaaa tgaacagaag ttgttcatta cggtaaatta caatatgatt
     2821 acaaaaaaca acaaagctct taaataactt ttaataaata ttaagagaag ttataattat
     2881 taataataga taaattgaag ttggaggata gaagatggaa aacattgcaa gaaaagaacg
     2941 gagacgttta gaacagacca aacgttttcg aaaagcaaaa cgaggggcag caatcgtggg
     3001 aactgcgatg gtaggctgtt ctgtcgctgc cccattagta cagccggttc ctgttcaagc
     3061 ggatgaaaca cctgttcagt tcggcgcaag aatcaataca gcggcattta tcacagaaat
     3121 tgctacttat gctcaaccaa tcgctcaagc caacgatcta tatgcatcag tgatgatcgc
     3181 acaagcagtt gtagaaagcg gttggggcag tagtgcgtta tctcaagcac cttattataa
     3241 tctttttggg ataaaaggca gctatcaagg acaaaccgtc tacatggata cgcttgaatt
     3301 tttaaataat caatgggtaa ataaaaagga gcctttccga caatatcctt cttttgctga
     3361 atctttcaat gacaatgcct atgtacttag aaatacttca tttggcaacg gttattacta
     3421 tgccggtact tggaagagca acacgaaatc ctatacagat gcgacagctt gtttgacagg
     3481 gcgttatgcg actgatcctg gttacgcagg caaattaaat aatatcatcg caacttacgg
     3541 attgacccaa tatgatacac cagctagcgg aaacgcaggc ggtggagcga ctacaggtgg
     3601 caataatact ggaagtgcag gtagtactgg cggttcaagc aattctggta atacaaactc
     3661 aggttcagca acttcgacca cttatactgt ccaatctggt gattctgttt ggggaatctc
     3721 aaataaattc ggtatcacaa tggatcaatt gatccaatgg aacaacatcc aaaacaattt
     3781 catttatcca ggacaaaaac tgacaatcaa aggtagccag gaaaatggct cttcgacgaa
     3841 taattccggt aacaatacca attcttcagg aaatgctggt acatcaaacg gaggacaaac
     3901 aactggtgcg aaatacactg ttcaatctgg tgattctgtt tggaagatct caaatgatca
     3961 cggaattacg atggctcaat tgattgaatg gaacaatatc aagaacaatt tcgtttatcc
     4021 aggacaacag ctaatcgtat caaatggcgg ttcttctaat gctggagcaa atactggctc
     4081 aaatactggg aatacaagtg gctctagttc gtccagctca agttcttcta atacagcttc
     4141 aggaacgaaa tatacagtta aagccggaga ctctgtttgg agcgtctcaa ataaatacgg
     4201 aattacgatg gctcagctaa tccaatggaa caatatccaa aataacttta tctacccagg
     4261 acaacaactg actgtttcaa acagtggatc aacaaacagc acgtcaggta atacaggttc
     4321 gtcaaccaat acaaataaca gcagttcagt taatactggc agcagttcgt ctcaaggcac
     4381 ttataccgtg aaagcaggtg aatctgtttg gagcgtggca aataaaaacg gcatcacgat
     4441 ggatcagtta atcgaatgga ataatatcaa aaacaacttc atttatccag gacagcaatt
     4501 gatcgttaaa ggtggaactt cggcaaatac aaatacaggt tcaactactt ctgcagcgaa
     4561 accaaataca ccgaatacgt ctgctacgac aagtacatca tccactggta atacgatgta
     4621 taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac aaacatcata tcacgatgga
     4681 tcagttaatc gaatggaata atatcaaaaa taatttcatc tatccaggac agcaagtgat
     4741 tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca gttactggtt cgaaaaccta
     4801 tactgtgaaa tctggagaat ctgtttggag tgttgctgac agtcatggaa ttacaatggc
     4861 tcaactaatc gaatggaaca atattaagaa caactttatt tatccaggtc aaacgttgat
     4921 tgtagctaaa taaaatagct gttcgaagaa ataacgattg aattccacaa aaatatttgt
     4981 tactataagg ctacttaaat atgacaacac ttgaaaagga agtagtaaaa agactgaagt
     5041 ttcagagagc gcatggctgg tgagaatgtg cacggatgct tttgaactcg cctttgagtt
     5101 gcccttgctg aatacccgag taagcaagcg gcggtgacgg ccgttacaac gttcgaggcc
     5161 ttttcactaa ggtaaaatta ggtggtaccg cgtagattac gtcctataaa aagagcaatc
     5221 tttttatagg atttttttat ttcttttgtg aagtttgaga aaacaaagca aaaggaaata
     5281 aaaataaaca gattctgccg gttttttcgt tatatttata atagaaacaa gtgttttcaa
     5341 tagaacagga ggacagcaaa tgagttacaa tcataaagaa attgagaaaa aatggcaaaa
     5401 atactgggca aaaacgaata ctttcaacac ccatgatgat cctgaaaagc caaaatttta
     5461 cgcactggat atgtttccct atccatccgg tcaagggcta catgtagggc atcctgaagg
     5521 ttatacggca acggatatcc tttcacgtgt gaaaagaagt caaggataca acgtgctgca
     5581 tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa tatgcgctag atacaggaaa
     5641 cgatccagct gagtttaccc aaaaaaatat cgaaacattc cgacgccaaa tcaattcttt
     5701 aggatttagt tatgactgga atcgcgaagt gaatacaact gatccggagt attataaatg
     5761 gacacaatgg atctttacga agctttatga aaaaggtcta gcttatgaag cagaagtagc
     5821 ggtaaactgg gtacctgaat taggaacagt tatttcaaat gaagaagtga tcgatgggaa
     5881 aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg cgccaatgga tgctgaaaat
     5941 cactgcttat gctgatcgct tattggatga tctagaatta gttgattggc cagaaagcat
     6001 taaagaaatg caaagaaatt ggatcggtcg ttcagtagga gcaaatattg aatttaaagt
     6061 ggctggtacg gataaatcct ataccgtatt tacgacacga ccagatactc tattcggtgc
     6121 aacttactcg gttcttgcac ctgaactaga tcttgttaga gaaattacga cccctgaaca
     6181 aaaagctgct gtagaagctt atatcgaaga gacagctaaa aaatcagatc taaagagaac
     6241 ggatcttgca aaagaaaaaa caggagtatt tactggtgct tatgcaatca atccagttaa
     6301 tggcaaggaa atcccaatct ggatcgccga ttatgtatta tcttcatacg gcacaggagc
     6361 catcatggct gttccagcac atgatgaacg tgactttgaa ttcgctcaaa ctttcggact
     6421 agaaattctt ccagttatcg aaggtggaga tgttgaaaaa gctgcttaca cagaagatgg
     6481 tacgcacatc aactctgaat ttctagacgg catgaacaaa caagaagcaa tcgataaaat
     6541 gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa gtcagctatc gcttacgtga
     6601 ctggctattc tcccgtcaac gttactgggg tgaaccaatc ccaatcatcc attgggagga
     6661 cggaacagtc acagctgtcc cagaagaaga gctaccatta cggttgccta agacaaaaaa
     6721 catcaagcca agcggtactg gagaatctcc attagcaaat atcgaggagt gggtcaatgt
     6781 cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg aatacaatgc cacaatgggc
     6841 aggaagctca tggtattacc tgcgttatat cgaccctcat aacaaaaaag aactagcaga
     6901 ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac attggtggag cagaacatgc
     6961 ggtacttcat ttactatatg cacgattctg gcataaattc ttatacgata tcggtgttgt
     7021 tcctacaaaa gaaccattcc aaaaactata caatcaagga atgatcttag gcgaaaacaa
     7081 cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct gatgatgtgg tcgaaactta
     7141 cggtgcagat acactgcgca tgtacgaaat gttcatgggg ccattagatg cttcgattgc
     7201 ttggagcgaa aatggcttag aaggaagccg taaattcttg gatcgtgtat ggcgtttgat
     7261 cgttgatgag aacaataaaa tgcgtgaccg tatcactaca ttgaatgatg gcaagcttga
     7321 taaagtgtat catcaaacag tgaaaaaagt gacagaagac tatgaaaatc ttcatttcaa
     7381 tacagcaatc tcccaattga tggtctttat caatgaagcc tataaagtgg acgctctgcc
     7441 ttatgaatat atcgaaggat ttgttcaact actcgcaccg attgctcctc acatgggtga
     7501 agaactatgg gcaatccttg gaaatgatgg tggtatttct tacgcaccat ggccaacata
     7561 cgatgaagca gcacttgttg aagacgaagt agaagttgtt ttccaagtaa acggtaaagt
     7621 tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat gagctagaaa aagcagcatt
     7681 agccaatgaa atagtgcaag aatatattga aggcaaaaca gtcagaaaag ttattgcggt
     7741 accaaacaag ttagtcaata tcgttgctaa ttaattggct ctttgtcaat aaggactgat
     7801 gagttgtgca aaatcaaatc tgggccagaa tgaacttcat tctgtctcag attttttgtt
     7861 atttcaaatt gattaattga ttgatcaaaa aggttttgat tttcatgttc tcaaacacgt
     7921 tcaatgtctt tttcttctga atggtcttgt aagagatctc tgtaatcatc aaatttttgt
     7981 ctattaatct tagtattttt tgatgtataa actacctgaa attgagagta cataccaaat
     8041 tcataaattt tttattagtg ggactagtga ttgtatggat tttgacgcat aatgaatgaa
     8101 gtatgagaaa aggagagaca aatggatcaa gaactattta ttatcgaagt attatcagct
     8161 aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa gaataatgtt caagctttta
     8221 agcttagtat ttttctctgg tttgcttttt ttcggagctg tatcgttcct atatcgccat
     8281 atgagtgcag tagtccgttc agctgaaggg atgcaaaaat taaataattt gtatcacttt
     8341 tcgtggggag ttggcggaat aacaattgtt gtgcttattg tttttcttct acttatttgg
     8401 ctccgttacc atcaattgtc gcgtcatttc gatcaatggc ttagtcaaag agcacaacag
     8461 tttttacata ataaaccaac ttctcaagat gatgactatc tttattttga gaagacttcg
     8521 acgagtcaag cttttcggat acaaaaaagt gattgccagt tattgctgag atcacttgat
     8581 gatttaccta tctacttagg cgaaagcaaa tcaaaattcg gaatgaacac attccatatt
     8641 tttttactag aaaacgaacc cagatgggaa aaaagccagt cttcgcctgg tggatacctg
     8701 acaactaaga tgagtacatt agtcactggt tttttcctca ttcttttagc tggaacaatc
     8761 tattatggga gatacactca gccaaaaatg tcttctcata taaatgctgc ttctcacatg
     8821 acaatgaact caactaacga tacgcatata caaaagacaa atgaagggtt gttagctgat
     8881 cctaagcaaa aggtaaattt gacaacacaa aagataaatg atctcaaact tgatacagag
     8941 acgcactctc tctatatgac aacagatagt ggtgctaatt gggtatttgt gccgattgat
     9001 tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg ggctgattcc tgaaggttat
     9061 tggatggaca acacatatga tatttccgcc gatttctcat ggtttatcta ttcttctggg
     9121 gatgatgtac gtctgctgac ttcaagagat aatggtaaaa catggcaaac gtctattatc
     9181 acccaatcag ttcagccgat acgttatcga aaagcggtat tttatggcaa cgatggtcta
     9241 tttatctgta catcagccag tgggatgtct gcagaaactt tgtacattta cactactatg
     9301 gatggcggaa tcacttggat aaaaagtgga agtacaatga tcaatcagcc agtacaaaat
     9361 gtcagcttcg ttacaacttc tttaggtttt gtttcgacac gtgaaagttt gttttataca
     9421 aacaacggag gacgctcatt caaagaatca gttctgtcga ttccggaaaa ctatcagaca
     9481 ggggggatag atctttttca atcaccaaat gaagttactc aaataagcgc gaatacgtta
     9541 gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg cagggaaaat gtttgcctgc
     9601 ctcttccgtt caactgataa cggggaaaca tggcaattcg ttcagcaact atcgcaagta
     9661 gaacaaggag attaaagaag agagattgtg agcctgacgt tcagcaccga gtcacaagaa
     9721 acaaattcaa aaaacagctt ctcatatttg ttgaatagtg taactcgtga ttcggagttg
     9781 acaagagcaa caagaagcga ttttgaagta tagcttctcg tattttacaa gatcgtgtct
     9841 tattgccgat aggttgtctc ttgaacaccg tttattcgta aaaagggatt gtgacaagtc
     9901 ttttgtcact acttaccgaa cgaaactgaa ggagctatcc aaaaagtatc attagtatta
     9961 ttctttgtgt ttctagtggc accactagta catttaaaaa agctatcgat catggactaa
    10021 tcatacatga tcgatagctt tttagataat gtttgttacg ctatctgaaa ttgactatta
    10081 taaagactgg cataaagcgt tggtgattgg agtagttcag aatgtgttcc tttttcgacg
    10141 atatcgccat tcttcattac aaggatcatg tctgcatttt caatcgttga caaacggtgt
    10201 gcaatcacaa aacttgtcct atcttttgtc acagcttcca ttgcttgctg aatcaatgct
    10261 tctgttcgtg tatctacgct agaagttgct tcatctaaaa taacgacagg aggattcgct
    10321 agaatgactc gagcaattgt caataattgt tgctgtcctt gagataacgt gccgttttcg
    10381 ctagaaatga tcgtatcata tccgtctggc agtgttcgaa taaagtgatc acattgtgcg
    10441 atttcagccg cttcgataat ttgttctctt gtggcatcca ttttcccgta ggcgatatta
    10501 tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa ccatcccaaa agaacgacgt
    10561 agttctccac gtgaaagctt ggtaatatca agaccgtcga attcgatctt tcctttattc
    10621 agttcataaa aacgcatcag cagattgact aaagtcgttt ttcctgcacc agttggacca
    10681 acgatcgcta ccgtttgttt tggctttact gaaaaatcga cttgattcat caatatttta
    10741 tctgatgtgt aaccaaactg tacatttttg aaagctattt ttcctttcgg ttgttctaaa
    10801 agtcttgcat ctggaaggtc tggaatttca tctgtttcat ctaatatctc aaatatccta
    10861 tcgattgctg ccattgcgga ttggatcgag ttgatcacat aagaagcggt agaaattggt
    10921 tcagaaatct gattgatgta ctgaagataa gcttgtaaga agccgatcgt cacaccacct
    10981 gatagaacaa gcatagcacc gaataccgca cttatgatga aggcgagttg attaatgaaa
    11041 cgaatggccg gatagatagc acagttcata aattgagcac gtttaaaagc gttgtattgc
    11101 tttttattta cttcgtgtat agcagcttct gcatgagctt gctgattgaa tgttttgacc
    11161 actagattac cagctaagat ttcttccatt cgattattta aaacacccag ttcatactga
    11221 ttctgttcag aaatctgttt gtttttgttc gcaatcttag ttgtaacaat tgaactgcca
    11281 acgatcagca ataagacgag caaagtaagc ttgctttcga tataaaacag catcagacca
    11341 gcagcagcta ttgttacgac agaagtaaaa aattgattga tacctgtcaa taacacttga
    11401 gaaagttgat tgagaccggt agttgtccga ctaatgatgt cacctacttg atgattgtca
    11461 aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt cttttcgcac cctcaatgtg
    11521 atcttttcgc ttaacgctgc cattgtccgt tcctgaataa atgaagtgat gctgcttaag
    11581 actgaacagc cgatcagcaa taagacaggg aacaacaatg cttgtttgat atcactgaaa
    11641 gaaagctgtc caatacctgt ttttcttatt tctgataaga gatcatcgat cccgattccc
    11701 atgatcaagg gcatggctac gactaatagg ttcccgaata aactgcatag aaacaatccg
    11761 taaaaatatt tatgttcagg tttgatcatt ttccaaaaac gtatcaaagc acgcgtgttc
    11821 aacgtttttt tcttttccat cgtatccctt ctttctatat tccttgtgat tttgcaaact
    11881 cctgataagt ttggcaatta gacagtagtt cttcatgagt accttgtcca acgatttttc
    11941 cttcatctaa aacaatgatg ttatctgctt gttggattgt actgaggcgt tgagcaacaa
    12001 tcacgagagt tttctccgac atgtgtttat gaagggctgc tcttaatgct gcatctgttt
    12061 tatagtctaa agcggagaaa ctatcatcga atacatagat ctctgctggt ttgatcaacg
    12121 ctcgagcaat acatatccgc tgtttctggc cccctgaata attagaaccg ccttgagcaa
    12181 caaagctgtc caatccgtca ggaagggtgt ccactagttc ttctaattga gcgatcttga
    12241 tcgctttaga caactcttct gttgaggcat attcatttcc catctgcaag ttgcttaaaa
    12301 ttgtcccgct gaataagaaa gccttctgag ggacataact gatgtgggag cggatctgtt
    12361 cttgagtcat ttgagtaaga ggaataccac caagggttac ttttcctatc gtagggtcac
    12421 taagtctcaa gagaagtttc gccaaactac tttttccaga tccggtcccg ccaacgatcg
    12481 ctgttgtttt tcctttaggt attgtgaaat caatatcttc tagaactgga tcagagattt
    12541 cagtatattt aaatgtgaca tgttcaaaag cagctgcatt tgtctgatca aaggttggtt
    12601 cagctactgt tttgatcgtc tcttcctcaa tttcgatctc tgcttgcagt atttcttcta
    12661 tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa taccatagct gcgatcatca
    12721 agtaagcaag tgtcagcata gagtattcga ctacagcagt cacgacaccg atttgtaatg
    12781 ctccttctgc tacaagattt ccgccaaacc acaaaataga agcataaacg attcccatga
    12841 gcaaaaaagc aattggagtg acccaagcaa atattcggtt cactttgatc atttgattag
    12901 catagtcagc aaagctctta ttcgttcgct tttcttcata tgattgatta tcaaaggcac
    12961 ggatcatatt aatcccagta aagaattctc tcaatgtgat ggtgatccga tccatttttg
    13021 gctggatact caaagataaa ggtgcccctc gtttcatcag tcgataaaca atccatacat
    13081 aaaaaacaac agagatcaat gtaacccatg ttagtaatag agaataacga aacatcatga
    13141 gaatggtgaa aacgcaaata accggtgctg gtaagatcat ttggcaaaat aaaacaatca
    13201 tttgctggac attatcgaca tcattcgtca ttcttgtcaa aagagatcca gaactaaaac
    13261 gactgatatc cttcattgac agctgttgga atttacggaa atatttctcc cgcgtttgga
    13321 atccaaacct agcggaagcc aatgctgaaa agtaactaga ggcaactgca gcgattgttc
    13381 ctagaaacgc tacaagcagc atttcaactc caattttttt tataactgag gcttcgccac
    13441 ttgctatacc tgtgtcgatc agctttgcta ctaattttgg tacacctaat gtaccggcga
    13501 tttctaaaca gatcatcaca aaggtaagga gagcgagtcc tttgtttttc tgtaagaatg
    13561 tttttaagat agacatatta ttcctccttt tttcctgata cttttcgatt ctataccttc
    13621 aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa aagaggtgag aaaaaatgaa
    13681 aaaaatgtat acgattggcc aagtatcgga actatttgat ttgccaaaat caacgatccg
    13741 ctattgggat gaacaaggat taatccgttc aagtagacaa gaagagaatg attatcgatt
    13801 gtttgatatc gatgatattt ttatgcttta tgatatcgtt ttttatagaa aattagatat
    13861 accgatcaaa cagatgaaga atttatatgg aaaaacattg acggagttat atgagacact
    13921 tgatgaaaca gaaagaagaa tccataaaga actggtggtg atgaaacaaa aacaaaaaga
    13981 gataagggag caaaaaaaac agttgaaatt gatgatcgat acaaacgagg aagaatttcc
    14041 tgtagaagag atcccttttg actgtatgat ctcaacggag tttgaagata ttgtggaaat
    14101 caaaaaattt ctacctaact attcaagctt tgggatgatg agtatgccag cttccagttc
    14161 acagacgatg tatggatttt ttatcgaccc tagtgaagta catttattta ctcaagacgt
    14221 gatttgggag aaaaaagata cggctgttta tcgtcgattc ttattgaaat ccgagatgaa
    14281 ccatgcggaa cgtaataata ttttagaaat cagagaaaga atgtatgaaa aaggatggaa
    14341 aacaggagaa gtgatcggcc agtatctatt gacgaatacg gatgaaaaca atatcagaac
    14401 tgaatattat catgcatgga tagaaatgaa aaaataggaa atatgtgttt aagataactc
    14461 gaaaatgatg gttgttttag ttataaagaa aaattttctg gttcgattac gggtttaatg
    14521 tgggggatta ttagtcgtgg atagatagaa ttttagtttt ttagaggaaa tatgtcttta
    14581 aaaatggaat ggttgcaatt cttagcgata tatacgatgt aattgtcctc ttaaaaaagt
    14641 atggaaaaat aattgtattg ggtgttatgt ataattcatg gtgaactgag actaatgaga
    14701 agaaaaattc atattgttat gagtgagatt gtatcagatg agaatgataa attaaatagg
    14761 tgcataaaag cattacactt aaaatacatt gttgcttaca ttattacaat atgttaataa
    14821 ggcaaaaata aatagatgga ttgaataaac atatttttta atcaaatagt ccctactgtg
    14881 actttcctca gctatcggtg atactaccga tagcattttt ttgcttataa aataattata
    14941 agtatttaga gatttttctt ctaacattct tcaaacaaga aaaatcacaa aggttattgt
    15001 tatttttata tattcttttt aagaatgatt gtttttttat agaaatttta aaaaataaaa
    15061 cacgttattg atggatagtt agtttgttat ttggtaatat tatagaagtt gactggtagt
    15121 gatttatttt tcgtcgtttt ataaaaatgt tattttttgg aaaaattcac aaatatgtaa
    15181 cgaatgtttt tctggaattt gctgtgttaa aaagcagtat gactaatata aatactattg
    15241 tcatttatgc aattttttat ggatagtaat tttagagggg aatcaatgaa ggaagaatag
    15301 aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata gcaatacatc ttcaagcttt
    15361 aaaattcgag agaatcatct tggtagtgga atcaactaca acaaaaggat taaaccaatt
    15421 aatagataga attaccaatg gaaaaataga aaaggtagtt attctataca aaagttgttt
    15481 aattcgcttc ggttatgaac ttagtgaaac cctttgcaat atatggtaca gaatatagaa
    15541 attattgaca ttacagaaaa tgatgaagat ttaatacaga ttgtcactat ttgtagatac
    15601 cttttacaag gaaaccgagc caataaagct aagaagatga ttaaggagtt gatggaagac
    15661 gatacaagtt aagaaagtga aactacgccc aaataaagag caaaaagagt aattggacgt
    15721 ggaaaatgca agaaatgaac catcgattcg gtggacagtt tattagtaat gacggtttga
    15781 gaacatccat gacgagaatg aaggaacatc ctaaatgcgt ttagttgaac caagtgccaa
    15841 ataatatggc caaataagcg atcagttatc gatgaatccc aagtattcta aactatatat
    15901 tcattttgat gctaagcatt gatatatttt tttgggattg atgaaggtta accaatacag
    15961 ggactcactg atgaaattct agagtctgac cttggtatca acgatttagt gattgtttct
    16021 aatggaaaag tataaaagta tataagtaca ttaacaaaat aactattagg gttacgctcc
    16081 agcttgtgca aggcactggc aggaggaatc gtgaaatcat aattatggtt aagccacacg
    16141 gacaactaaa agtcatacaa agctatcgaa tcaatcaaca gaagacaatc ggcaatcatt
    16201 agctttgttt acagcttaca ttgcaacgct tgagttgaac cgaaaatacg agggaggtaa
    16261 cgcagccatt ttgagttggg gaatcttttt agaaaattat cgggtacctt gttgtttagt
    16321 caaaattata agggggagta atagtgagga acaaatttca taaactgtta agtatgtttc
    16381 tagttatgct tattgtgatc aatcaatttg ggaacataac ggttctagct gagtctttag
    16441 cagaacagcc agagcgttcg ctgacgatcg aagttgatca agaggaggct gctttgggtg
    16501 agcagttcca gttgcgagtc agaggaacac cagacctgct aaatgcattg gtcattgata
    16561 agagtgagga tttgattgaa ggggaagtga agcaactcaa tgattacgaa cgtctgatta
    16621 cttattcttc ccagcattca ggtaaatacg aattgaccgc aagaagcggt gatattcaat
    16681 caaatacggt ctcaatagaa atcagtgtac cagaagaaag cacaagtgag tcttttaatg
    16741 taccagaaga aagcacaagt gaatctttta atataccaga agaaagctta agtgaatctt
    16801 ttaatgaagc cagatcatct gagccatcta taacgcagga atctcagatt gaaagacaag
    16861 aggagctctt gaattatgac atcggcatct ctgctgagcg ccccactttg ccgagcaggc
    16921 atacacaaac gttaaaggga tacattcaag gaggcgctgg cgatattctt gaagaatatg
    16981 gggagatggt cgtacgagtt cctagagcat cgattggctt aattgagttc attagagtgg
    17041 aggtcgctga tgattcacct ttaaagccac tggcatttta ccaagaaggc acagacgttg
    17101 tttttccatt tacctttgat tatgaaggat taaatgaagc cgctcagtcg tatacattca
    17161 gtatcacgtt tgaagttgct ttctttcaat caggcggtac tgagccaaat aatgactttc
    17221 aagtgagtct tacttatgct gagcgagcag caaacacgga attttcaatt acgcctattc
    17281 cttcatcaag acccattttt tcgaaattat actatggctc tagagaaatc gacagccaag
    17341 gaaatcttgg gaatctgctg attgacgggc aagacgtgac caacagtaat aaatttattt
    17401 tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt ggttaccgat gtactaccgc
    17461 aaggaacaac tttggcaccg aatccgacta catggagttc cactggaaat agagaaccta
    17521 tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg tgaagcaaac gttagaactc
    17581 attatgtttc cgaggaattt gtggacaaag tatcttttaa taaggaaacg aatacacttg
    17641 ttgtggactt tggtaatcta gcagagggtc aatcgtattt tattgaatat gctcttgaag
    17701 tgaccgatgt cgacttgttc aatgaaggaa gacaagagga tgggttttct cggaatcgag
    17761 cgagtatgac ctacaataat caggtaatga gccgagacta ccgcttgaga atccctgaaa
    17821 gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa aaatgttatc aatctcaatg
    17881 aaaatgaact aacgtatact ctgcatgtct cgatgttttc tggaacaaga aatacgcttg
    17941 ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc atttctatca gatattccct
    18001 ctttcattga tgccgaagtc aataatggaa tagttcgttt cagtgcgaat aatacgattg
    18061 gtggtccgac aagttttacc ctctctttta aggtcaatgt agaggcgtat gcggtcggcg
    18121 atcaaatttt aaactttgca acgcttgtga atagtgacaa tcgattgaat acgagtactg
    18181 taagaacaag gaaaatcgat gggcgtatta aagtaattaa aactgatgag aatggccaaa
    18241 ggctggcagg agcaaaattt gaaattttat caagcgattc acaagtgata caagaaggta
    18301 taacggcaga aaacggagaa tttttaagtg aaccgcttcc tgtaggtagc tatcaagtcc
    18361 gagaaacaga agcaccggaa gggtatcttt tagatgcgac ggtacatgat gtttttataa
    18421 atgaatactc catagaagaa gtgacgttaa ccattgaaaa catccttgat acgggtggtg
    18481 ttgaactaat taaacatgct gaaggcagtg gtgaagtcct tcaaggagct gtttttgagt
    18541 tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DASHXG010000052        18080 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.053, whole genome shotgun sequence.
ACCESSION   DASHXG010000052 DASHXG010000000
VERSION     DASHXG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18080
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.053"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            598..1287
                     /locus_tag="U2R59_002134"
     CDS             598..1287
                     /locus_tag="U2R59_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8966488.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="U2R59_002135"
     CDS             1274..2482
                     /locus_tag="U2R59_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8966489.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="U2R59_002136"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="U2R59_002136"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEM8966490.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="U2R59_002137"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="U2R59_002137"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEM8966491.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="U2R59_002138"
     CDS             complement(6585..7280)
                     /locus_tag="U2R59_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEM8966492.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="U2R59_002139"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="U2R59_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEM8966493.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="U2R59_002140"
     CDS             complement(8479..8670)
                     /locus_tag="U2R59_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HEM8966494.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="U2R59_002141"
     CDS             complement(8691..9581)
                     /locus_tag="U2R59_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEM8966495.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="U2R59_002142"
     CDS             complement(9568..10335)
                     /locus_tag="U2R59_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8966496.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="U2R59_002143"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="U2R59_002143"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEM8966497.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="U2R59_002144"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="U2R59_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEM8966498.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="U2R59_002145"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="U2R59_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEM8966499.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="U2R59_002146"
     CDS             14906..15289
                     /locus_tag="U2R59_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966500.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="U2R59_002147"
     CDS             complement(15457..16215)
                     /locus_tag="U2R59_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HEM8966501.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="U2R59_002148"
     CDS             complement(16233..17051)
                     /locus_tag="U2R59_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEM8966502.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="U2R59_002149"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="U2R59_002149"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEM8966503.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="U2R59_002150"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="U2R59_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEM8966504.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
BASE COUNT         5032 a         3739 c         3297 g         6012 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgcggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggag tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaatgg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg tgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tatatttttt atccacagat gcaagaggaa atctattgat ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa cttttttttg acaactgtgt ttttctcttt tttctttttg
    18061 tcgattgtgt ggataattgt
//
LOCUS       DASHXG010000053        17223 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.054, whole genome shotgun sequence.
ACCESSION   DASHXG010000053 DASHXG010000000
VERSION     DASHXG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.054"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(97..1116)
                     /locus_tag="U2R59_002151"
     CDS             complement(97..1116)
                     /locus_tag="U2R59_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8966505.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1138..2145)
                     /locus_tag="U2R59_002152"
     CDS             complement(1138..2145)
                     /locus_tag="U2R59_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEM8966506.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="U2R59_002153"
     CDS             complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="U2R59_002153"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HEM8966507.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2796..5090)
                     /locus_tag="U2R59_002154"
     CDS             complement(2796..5090)
                     /locus_tag="U2R59_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HEM8966508.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5350..7515
                     /locus_tag="U2R59_002155"
     CDS             5350..7515
                     /locus_tag="U2R59_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8966509.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7819..8652
                     /locus_tag="U2R59_002156"
     CDS             7819..8652
                     /locus_tag="U2R59_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEM8966510.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8754..10454)
                     /locus_tag="U2R59_002157"
     CDS             complement(8754..10454)
                     /locus_tag="U2R59_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966511.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10961..12121
                     /locus_tag="U2R59_002158"
     CDS             10961..12121
                     /locus_tag="U2R59_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8966512.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12137..12580
                     /locus_tag="U2R59_002159"
     CDS             12137..12580
                     /locus_tag="U2R59_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966513.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13063..13593)
                     /locus_tag="U2R59_002160"
     CDS             complement(13063..13593)
                     /locus_tag="U2R59_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HEM8966514.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13698..14249
                     /locus_tag="U2R59_002161"
     CDS             13698..14249
                     /locus_tag="U2R59_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8966515.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14402..14875)
                     /locus_tag="U2R59_002162"
     CDS             complement(14402..14875)
                     /locus_tag="U2R59_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8966516.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15013..16485
                     /locus_tag="U2R59_002163"
     CDS             15013..16485
                     /locus_tag="U2R59_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8966517.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16482..17192
                     /locus_tag="U2R59_002164"
     CDS             16482..17192
                     /locus_tag="U2R59_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HEM8966518.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5356 a         3093 c         3539 g         5235 t
ORIGIN      
        1 tttttacaga taaacaatgt gttagaagta gtatcttctt ttacataaaa agctgaccat
       61 aggataaatg gtcagcgtat ttagtgagtc agctatttag tatgggtttt ctaaaggaac
      121 gactgtctct cttttgatca agcgatgagg gatgaccaaa cgtacgccac tgctcaattc
      181 ttcatggatc aattcgcgca gcttttgcat agcgacacgt cctaattcgg agatatcgat
      241 atcgatactt gtaaggtaag ggtgtgttaa tgttgagaag atcgagttgt tgaagctaat
      301 gacggagagt gtctctggaa tgacatagcc atacatttgc gccaactgca tcgtgcgaag
      361 ggcgaagata tcgtcaatga ccaccaatgc tgtggcttcg ttttctttca acgttttctc
      421 aaaggacaga taatcctccg gatgctctag tactacactg gataacgcag gaagaccagc
      481 catcatcatt gctttttgat aaccgaaata tcgttcgaaa tacaaacttt catgagtcgt
      541 gtttgtcaca aacaggatat tcttatgtcc attctggatc aaaaattctg ttgcttgttt
      601 acctagaagc tggttatcat tatctacata aacgatttcg ttctcatgat gataaggctg
      661 tccgatcaaa gtgaaaggga tgtggttttg gtataaataa tcaatgacag tatcttgact
      721 atctgaatac actagaataa aaccatctac ttgtttttgt aaatgcatac gctggacgtt
      781 ctctaacagc aattcaaaat ttttagcagt agcgattgct gtagtcatat cataattccg
      841 cgcttcttcg ttgattgctt ccatgatctc aagataaaat gggttaccga tccgctcttt
      901 tgaatcaaga gggggtaaga ttacgccgat ggcactggaa atgcgttttc ctagattgcg
      961 ggcagtcatg ttaggaacat aacctagttc atccataatt tttcggactt tcttctttgt
     1021 tgtctcggaa atactaggat gatcgttgat gacacgagag acggtcgagg tggcaacacc
     1081 ggcttttttc gccacatctt ttacggtaat agccatgata aaaacacctt tctcttgtta
     1141 ttgtgcagag aaccgataaa tcgtctgact gatccgttct tgaccaggat ggaggttgat
     1201 cgatccaaat ttggggaaat gaacgatatc agggatttct tgcggttcga ttgctaatcc
     1261 gtagtttgaa tgcatctgtt ttccattgac agagaaatca gcttcgaatc cagtcgtaga
     1321 aaataatacc atacttttat tagaagttgc tatagtcatt tggcgaccag aatgcttctc
     1381 gaataattgt aaggaagttt tggaaagcct aggatgatgc aaaagaaata catcatctag
     1441 tccatctgga taacatgcaa ggatctcttg cagtgttggg gattttctaa agtcgattgg
     1501 cagtttttct ttttttgtcc aatttccagt aggcagtttt tcttgatcta attcaagcac
     1561 accatctaaa aagaccgtta actgatgttc atagatgtct cttgttccat ttcctgaaag
     1621 gttgaagtag gcatggttgg tcggattgca gatggtttca acaaggctac tagcagaggt
     1681 tgtcatctct aattcgtttt ttgttaaacg gtaagtgatc gtagcagtga ttggtcctgg
     1741 ataggtagaa aattcatctt ttaagtaaaa gaccacacct attgatgatg gagttttgaa
     1801 aacttctact tcccaaaatt ggaaagacca gcctttcgtg ccaccgtgga tatggtgtga
     1861 tccgcagttt ttctccaatc tatgctcacc ccaagaagca tcccggatcc ttccggctac
     1921 aggtccgaca gttgctccaa aaaagctttt gtctgttaga acatcttcga aacgatcgta
     1981 agacaataaa acattttctg attttccttc tttgtctggt gcgaagattt ggtgcaggcg
     2041 ggcaccgtaa ttgagaagaa cgacttctaa gtagtcgttc ttcaatgtga ttttctttat
     2101 ttcagtctct ggaactggta cgacggagat ctctggatta tccatggtca tgccactttt
     2161 ctttcaagta atcgatcgta agaaaagtcg tatcagggac aagcgggatc tcctctccaa
     2221 ggtcttcagc acgtcccacg ccaattggtt gagcgccact tgagaggatg gcttggatac
     2281 cggcttgcgc gtcttcgatc ccgatacatt cttctgcttt tagtccgaca gcttttgctg
     2341 caaggaggaa gatatctggc gcaggttttc cgtttgttgc ttctgccggg tcggcaatag
     2401 catcaaagta aggtgtaaga cccatttttt caagtaggaa tggcccgttt ttacttgcag
     2461 aagcaagagc aatcttgatt ttttcttctt ttaaagaatc cagtaaaggc acgaccccgg
     2521 ggaagacatc ttttggttcg atcgtctgga tcatctctaa ataataatcg ttttttcttt
     2581 tcgctaattc tgcaaattct tcctttgaaa aagagtgttc ttttccgcca taagctaaaa
     2641 gcaaagagag tgagtcttct cggctgacgc cttttagctg ttcgttgaat gtgtggtcga
     2701 tcgtaatgcc gatttcctga ccaagctttc gccaagcacg ataatggaat tcagcagtat
     2761 cggtaatgac accgtctaaa tcaaacaata cccctttaaa catttgcttc ctcctttctt
     2821 agcgttattt ctagacgatc cgctaaagaa taagactgtt catagacgta aatttctaga
     2881 ggagaacctt ctaataactc gaaagtaact tgttcatctg tgactgagat gaacaataaa
     2941 cgtccgcgat aattgatatg gaaagaataa gctttccaag tttttggcag aaatggtgcg
     3001 aatctcaact gatcatgggc agttttcatt tgagcaaatc cttggacaat cgacaaccag
     3061 ctaccagtca tggaagtgat gtgcaagccg tcttctgtgt cgttattgta attatccaaa
     3121 tccaagcgag ctgttcgctg gtacatttct acagctttgc tttccattcc taattctgct
     3181 gctaaaatcg aatggatact tggcgaaagg gaagactcat ggacagtcat tggttcatag
     3241 aaatcaaagt ttttttgctt ttcttctttt gtaaaagtat cattgaagaa ataaatcccc
     3301 tgtagtacat ctgcctgctt gatgaagcaa gatctaagga ttttgtccca agaccaatgc
     3361 tgattcagag gaagatcgct tgtgggaata tcggatacag gcatgagatc tttatctaag
     3421 aatgtgtcat gctggacaaa gattcctaat tcttcgtcaa ctgggaagta catgttctct
     3481 gcgatatctt tccatttggc tagttcttct tcgctgatag tgatagcagc ttctttttga
     3541 taagttaaat aattttctcg cgtgtaacgc aagacccaag ctgcgatcgt atttgtatac
     3601 caattgttat tgatattgtt ctcatattcg tttgggccgg tcacaccgtg gatcatgtat
     3661 ttatttgctc gttttgaaaa atggacacgg tctgcccaga agcgtgcgat ttctgctaaa
     3721 acttccagtc cttcattttt caaatattcc gtatcgccgg tgtaattcgt ataattgtag
     3781 attgcatagg caatcgcgcc atttcggtga atctcctcga atgtgatttc ccactcgtta
     3841 tggcattcga caccagtgaa ggtgaccata ggataaagcg cgccttttaa tccttgttgc
     3901 tgagcgttgt ggattgcttg cggcagttga ttatgccgat atttcagcag attcttagtt
     3961 acttcaggtt tggctaaagc aagataaaga gggacagcat acgcttctgt atcccagtaa
     4021 gtggctccgc cgtatttttc tcctgtgaat cctttggggc cgatattcaa tcgttcatct
     4081 tcgccgtagt aagtagagaa tagttggaac aaattgaatc gaataccttg ttgtgcttct
     4141 tcgtctcctt cgatgaccac atcggcaagc ttccatcgtt ctgcccaagc cgctgtttgc
     4201 tcttcttttg cttggatata attgtttgtc tggttcgtta attctgagac agctttttct
     4261 gcttgctgcg cttctggaat atctctacta gtaagaacga taatttcttt ttccactgac
     4321 catgtctcac cttgagataa ttctgcagac aagcaaccat gtaatgctaa agtatcttcg
     4381 tgatagtcag ggatgactga ttttccatta acgaaatggc gcattgctgc agtaacagta
     4441 aattgttcaa tcccaaagtt gtttggaata gttttagtcg tcaaatagcc gatttcttct
     4501 atagttccac gatcaatctc attccaaaaa tgttcatcat agttgctgtc ttcgttttga
     4561 acatttccat ccaattttga tacgagtttg actgttccgc taccttcaag catttctata
     4621 gttaaataga tataagctga ttcttttttg acaatgctca gaaaacgttc gaaggaaatg
     4681 cgtactttat tagtagaagt agtgattgtg aatgtacgag ataatacacc atttttcata
     4741 tctaattccc agtaaaagtc ttctggttcc aaagaagcca agtcgatcag ctgatcgttg
     4801 atcgaaatat ctatcgcgat aaagttcaag gcgttgatca cttttccaaa gtattctgga
     4861 taaccatttt tccaccagcc gacacgtgtc ttatcgggat accagacacc cgccaaataa
     4921 gtaccttgat ggtggtcccc tgagtaagtt tcttcaaagt tcccgcgcat ccccatataa
     4981 ccgtttccaa tacttgttaa agattcttgc agtcgaagat tttttttatc taattgtgtc
     5041 gtgctgattt tccatggatc aatagcaaat agtcgtttga tctgtttcat ttttctcctc
     5101 ctaatgagct gttttatacg ttcataataa acgcaaccga ttgcacaagt caatagacaa
     5161 aagaaaatat ttcatagaaa aaagcttaaa aaaataaatt tttaggagaa aattatagaa
     5221 gggaacacac gtattatagg ttttatagaa tggtatagac agaaaaataa aaaataaagc
     5281 atttacaaaa aagaaaacgc acgctataat acgtttaacg aaaccgattg cgtaaaggag
     5341 ctaaacggaa tgaaaaagat atttagtttt gaattttggc aaaaatttgg aaaggcttta
     5401 atggttgtgg tagcagttat gccggcagct gggttgatga tcagtatagg gaaatcaatt
     5461 cccttgatca atcctgattg gacgccgctt gtcacaacgg gcggagtaat tgaaaatatt
     5521 ggttgggcaa ttattggtaa tcttcatatt ttatttgctt tagcaatagg aggaagttgg
     5581 gcaaaagaaa gagcaggcgg agcatttgca gctgggatct catttatttt aatcaatcgg
     5641 atcactgggg ctatctttgg tgtcacaagt gacatgcttg cgaatgaaga tgcatttacc
     5701 cacactctgt tcggtacgaa gatcatggtt aaaggatttt ttacaagtgt attggaagca
     5761 ccagctttga atatgggagt attcgtaggg atcatcgctg gatttgtcgg ggcaatggct
     5821 tataataaat actataatta tagaaaattg ccggatgctt tgtcattttt caatggaaag
     5881 cgctttgttc cgtttgttgt tatcttatgg tcaacaatcg tggcattgat tcttgctgtg
     5941 gtgtggccaa acgtacaggc tggaatcaat aattttggtt tatggattgc agaatcacaa
     6001 gaaagcgcac cgattctagc accgttttta tttggaacat tagaacgttt actattgcca
     6061 tttggattgc atcatatgct gacgattcct atcaactata cacagcttgg cggatcgtat
     6121 gagattttat caggcgcaca ggcggggaca caagtatttg ggcaagatcc gttatggttg
     6181 gcttgggcca ctgatttagt gaatcttaaa ggtgcagggg atatgtcgca atatgagttt
     6241 gtgttgcata actggacgcc ggctcgtttc aaagtaggac aaatgattgg ttcttcaggt
     6301 atcttgatgg gaatggcttt tgcgatgtat cgtaatgtcg atcctgataa gaaagcaaga
     6361 tataaatcaa tgtatttttc agcagcgttg gctgtctttc taacaggtgt aacagaacca
     6421 ttggagttca tgtttatgtt tgctgctgtg ccattatatg tcatttattc agtgatccaa
     6481 ggggctgcat ttgcgatggc agatatcttg ccattgcggg tccattcatt tgggaatatc
     6541 gaattgctga ctcggacacc gttagctatc aaagcgggtc taggtggaga tcttatcaac
     6601 ttcgtgttgt gtgtgatcgc ttttggtgtt gttacgtatt tcttagcaaa tttcttgatc
     6661 aaaaaattca actttgctac accgggacgt aacggaaatt acgacaatga cagtgaagaa
     6721 accgttgtat ctaacagcgg aacaggaaca gcagatcagc aagtggtcca gatcattcat
     6781 ttgctgggag gaaaagaaaa tatcaaagat gtcgatgctt gtatgactcg gttacgcgta
     6841 agtgtaaatg atcgagaaaa agtagggact gaagaagcct ggaaacgagc aggggcgatg
     6901 ggattgatcg tcaaagacaa tggagtccaa gcagtttatg gaccaaaagc agatgtcttg
     6961 aaatcagata tcgaagatct gctgcaatca ggagcagaga ttccagagcc agaaatggtt
     7021 tctacaggaa atggacaagc aggtagtaag caatacttag gtatagaaca agaactagtt
     7081 tccgcagctt ctggagaagt gattccttta tctgaagtaa aagatccggt attctcacaa
     7141 aaaatgatgg gtgacggctt tgctgttatt ccaacatcaa gagaagttgt tgcgccgatc
     7201 gctggaaaag tgacaagtat tttccctagc aaacatgcaa ttgggctgga aacgaaagat
     7261 ggtatcgaag ttttgatcca tatgggaatc gatacagtcc aaatgaatca gccagctttt
     7321 gagattgctg tcaaagaagg ccaagaagta ggaacaggaa cgaaattagc tgagatggat
     7381 cttgatgtga tccaaaacga agaaaaagat ccaacgatca tgatcgtatt tacaaacgat
     7441 aaagtagaag aagtagtgat caagcaatta ggtacagtga cagctggtaa agtgatcggc
     7501 tccattaaaa tgtaaggaga ggttgtgaaa aagctgtcct gcatcaagtc ataagaacag
     7561 ccaaacaaaa atagctcctc ctatttttcg tttggttggg cttattaccg agaagcagca
     7621 gtttgaatac tgtttagtgg agaggtcgtg aaaaagctgc cctgcaccaa gtgataaaaa
     7681 cagccaaaca aaaaatagct cctggtccat tgagcttatt actgaggagt tagcaggaga
     7741 acactatttg ctggagaggt tgtgacaaaa attttgtcac aacccttttg tttcgaaatg
     7801 aagacaagga gaaaaccaat gaaattcatg acactcaaca cgcatagctg gcttgagcca
     7861 gaaccagaga aaaaattgca agaattagca gataagatcc tgttagaaga ttatgaagtg
     7921 attgctttac aagaaatcaa ccaattactg gaatctgaag aagtagaacc tgcgaagcta
     7981 atgaagttct gtccggtaaa gaatcaagta cctatccgta aagataattt tgcctaccgt
     8041 ttagttcagc ttttaaagga acacggaaaa gagtattttt ggagttggga aatgagccac
     8101 atcggttatg ataaatatga agaaggaaat gcactgctta cgaaaaaaac attggaaagt
     8161 caggtcctta ccgtctccca atttcaaaag aaagaagatt atcagacacg caagatcttg
     8221 attgggaaaa caaagataga tgatcaggac atttttgtct cgagctgcca cttttcttgg
     8281 tggacagata aaaaaagtgg cttttatttt gagtggaaaa acttggaaaa ctactttttg
     8341 gaaactcgcg taccactttt tttcctaggt gatttcaata atccagtaga ctctcaaggt
     8401 tattatactg taagagaaag ttgccttctt cttcaagatt cgtatgttgt cgcgaatgaa
     8461 aaaggaaaag cagctactgt ggaaaagaaa atagatggtt gggaacaaaa tacagaaaaa
     8521 ttgcgtatag attttatttt cgtccctgaa ggaatgcagg ttaaaaaata tcaacggatt
     8581 tttgatggga tcgatagtcc aatcatcagt gatcactacg gggtggaaat cgaattagat
     8641 gtgaacgaat aaaaaatata acatataaca taaaaaaact gattaaaata aaactctcca
     8701 aacgattata ccgtttggag agttttttga tcggatgtat ttatcccttt tgcctaagca
     8761 cgtaaaagct tgtatctatg ataaataaat aaacatagca aggtaaacca gccaatcaaa
     8821 gtaagagaaa gaatgaaata gaaatagatt ggcgtttgat aatgaagcgt gagctcgttg
     8881 attccttttt gctgcttcac gattggggtc ccgatatctg ttacttcata atcagtcaat
     8941 gtttttccat tttgctgtag cacagtccga tcgtagacga taacagggat atgaacagtt
     9001 ttgtccccag tgtttttcca cttgattgtc aaaagaccgc ctggatgtgt ttttataaaa
     9061 gttgtttcgt tttctagtat ttcttcgtta taccggtcgt atttattgtc ttttgtctcc
     9121 ttatagattg gcagatagtc aggtgtggtt ttttggaaaa cgaacaagct ggtagacata
     9181 tctttgctga agaatgtttt ccttgcttct tccggcgtat cgaatagata agtatgtcga
     9241 ctgacaaatg tttcattttc ccacttttcc agatgctggt ataagttctg gatcgtctgt
     9301 gctgaaaaaa taagaatgcc aaatatactt aaaagacgga accacttttg ttcagaccac
     9361 tggttcagtg aaagggcaag gtaaagtaga agcaatagcg taaatggcac gaaaaatcga
     9421 aatggaaact ggatcaaact aataaaaggc acattttttt cgatcaatgt cgtccatgga
     9481 atcaagctag tagaaagaaa aaagaaaaca agacttgtgt acaacacgat tttttggaat
     9541 aaggtgttct tttgttgaaa gaaaataaaa agcaaaaaac ctgataatat caatatagga
     9601 aaggccttag ggtaatggag ccaataactg ccatccagat ctatcgcctt ttgactcatt
     9661 tctctgttaa caaagggagg aagaatctta ttcccactgt aaacaatagc taatcctgcc
     9721 caaatatttg ctgtcagaac aaaataaagc aagaccgact taatcagttg aagcagtgct
     9781 tttccttttt cagtctggtt aaaaaagtaa taaagataaa aagggatata catcaaagct
     9841 aacatgatcg aagacagtaa atggatctgt gtcataagtc ccactgagac agcgactttg
     9901 ataacaggga actttttatg aaggacgaaa tcagcaatag ggatcataca taaaggataa
     9961 aaacaagtcc cccagctagt gaatccttgg ttgatagacc agtattgaat agaatacgta
    10021 ctcatgaata aaacggctac tggtacactt acccaatttc gaacattgac atatctcagt
    10081 aaaatcagca tagaaaatcc tgaaataaga taaagaatga aatttgaaag aatctgataa
    10141 tgaaaccagc tacctgcaag caacacgatc aatccttgta aataagcgaa aaatgggccg
    10201 taaacggcat tcacgatcct gccactttgc tggaatccat aaagggaagg aaaataatgg
    10261 aaatccccat atttaatttg ttgcgcggca tcatagaacc gattgtaatg gaatggggca
    10321 tcagcaccca aaattagttt atgtgtgaat aaatgaggca tgagaaatgc caaagcaatg
    10381 aaaaaaattg ctaaaaatgg gccatatttt ttcaattgtc gaactccttt gcaaacttta
    10441 gataaattca tcatatatcc tatgcgagag gtaggcaaga aattagaaaa ttcatgaaaa
    10501 tatttatgaa ttttacaaga aaaacataag tgaaagttct aaggagagag gatgcgacat
    10561 aagttttgtt gcatctcctt gttttgaaac agaatttttc ttaatactcg aaacaaagta
    10621 gctttttcat gacctctcgg taaacggtgt tcaatcagct gcttctcggt aataagctca
    10681 ctagcctaga aaatatgaga agctattttc tgactagcgc tcttattact caaagcataa
    10741 cgcagttttc acaacctctt ccttaaacgg tgttcaaaag cttgcatctg cggtaataag
    10801 cccaacccaa caaaaaatat gagtagctat ttttttgggc tgtacttatt acttgatgca
    10861 ggacagcttt ttcacaacct catcggcttt cattttctat ttttttcctg aacccatata
    10921 ataaaagaaa gaacaaaaaa acttgcaagg gaggacacat gtgaagcaga gtaagcaaaa
    10981 acagtctcgt cgacttttgt ttcgtttgtt tttattaata tgtatcgtcg tagggttact
    11041 gatcgcttta tatccatttt atgtggattc tttaaatagt tttattgatc aaaaacgtat
    11101 cgaacaagta caaaaacgga ccgcagctga aattgaagtg cagcgaaaga aaatggagga
    11161 gaaaaaccaa cgattaactg accaaggatt caatcctggt actgatcctt tcaatgaaaa
    11221 gaacagaaat gaaagtacaa catccagtca attagaggaa tggctgatcg gaagtatcaa
    11281 tatacctaag atccaattaa atatttcact ttatgatcgg ctcaatggta ggatccttga
    11341 aaatggagca ggcgtcttgc aaggaacctc tttcccgctt ggtggaaatt cgacgcattc
    11401 agtgatctct gctcacagcg gtttacctaa tcgacggtta tttaccgaat tagatcgttt
    11461 agaaaacgga gacacgttta ttttgactgt tttgggggag aaattggctt atcaagttaa
    11521 aaatatacaa gtggtactgc cagatgacac gtctgttcta acgatttcag aaggagaaga
    11581 cttagttacc ttgcttacat gtacgccgta tatgatcaac acgcatcgtt tgctagtgac
    11641 aggacatcgg attccttata acgaatcggt aaaaaaagaa gaaggaaaag gaaatcagga
    11701 aagaaccatg cggcaatggt ttattcttgc aggaacgata atagctgtag tcatactgtt
    11761 agtgtttatc ggacgactaa tctatcagta tagattaagt aaaaaagtgc ttgatttttc
    11821 atttattatt agtgattcgt cagggaaacc ggtaaatggt agttcattca ttttgaaaca
    11881 taagaaaaaa acacttacta gaaatggtgt gccgttttca gtacaaagcg accatcatgg
    11941 gaaagtcaag ctggatcaat tgcctggtgg aacttatcga atcgtttcag ctgatgatcc
    12001 taaagttgct gtttcttttg gtattagaaa agtaaaacaa gagaagatat acttttttga
    12061 ggggcgaaaa cttgtaaaag agcttcaaaa aaatggtttt tattttaaaa tcaatgaata
    12121 agtaaggaga gaaaaaatga tccgcacaac aacaaaattg tctgccaaag aactggaatc
    12181 tgttctatcg atttggctgc atgctaactt ggattctcat gaattcattc catcaactta
    12241 ttgggagaat caagtagaat ctgttaggaa agctttacca gatgcagtga tttacttagc
    12301 agaaatagat caagaaatta ttggttttgc tggggtgatt gatcagttta tcgcaggaat
    12361 ctttgtgaaa agggaatacc ggcaacaaag aatcggtacg caactaatga aaaaaataaa
    12421 agaaaccaat aaaacactga ctttgacagt ctatcaaaaa aatcaatcag ctattcattt
    12481 ctatctttca caaggtttta caattcaaac acagcaaaaa gatgaagcag taaatgagga
    12541 ggaacttgtg atgaaatgga atcaaaacgc tgatttttga tgaacagaat aacgaaataa
    12601 tgctcccagc ctaatttttt gctgggagca ttatttcatt ttgaagtcac taatttaact
    12661 gtgtgaatat gcagttgtta caatctttga taaacggtgt tcaatcagct gaccctcggt
    12721 attagctcaa aaaacggcaa aatatgagga actatttttc catttgtttc tctaatactc
    12781 aggtcaaaac gctgatttca caacctcttg ataaacggtg ttcaaacggc tgcttctcgg
    12841 taataagccc actagcctag aaaatatgaa aagctatttt ctaactagcg ttcttattac
    12901 tcaaagcata acgctgattt cacaacctct tgataaacgg tgttcaatca gctgaccctc
    12961 ggtattagct caaaaaacgg caaaacatga ggaactattt ttccgtttct ttctctaata
    13021 ctcaggtcag aacgctgatt tcacaacctc tctttcacaa ccttatttta ctcgtttata
    13081 attttcatcg aagtattttc cgctacggat atcatctggc attccatcgt atggttcttc
    13141 gctaataaca tcttcattgt ctatacctgc atcacccata taagtgatcg tagcaaattc
    13201 aggaacaagt aattttggat aagtttcata tttttcacga gctgcttcca tttctgcgat
    13261 atgttcgttt tggaaagtaa cagtgatttc tggatgttct tcaacccatt tagggaaaaa
    13321 gatcattccg tgaagtttct tttcatttgg cataaagtcc aatgccacgt ctgtccctgt
    13381 tggctctgtc caagtgattt tgaatacgcc gtccgtcaat ttaacgatat cagcttcttg
    13441 gtcttttacc caacggcctt tgaccattcc gccatggata cggtaatcaa cagtatggtc
    13501 atttttggca taccattcat attcccaacc attgtcatac gtatagataa agtgagttcc
    13561 aataaaatct tccaattctt taaattcttt catgtttaag catctcctta taaattaaaa
    13621 catgtaataa actacatgtt ttcgattact catttatgat agaatggatt taaagatttg
    13681 tcaaggaggg aaaactgatg gcaagaaaaa atacacttcg atatattttg ttagggttat
    13741 taagtaagaa gaagatgaca ggatatgaat tgaatcaatc gttcaaaaat gaaataggag
    13801 aattttggca agcaaaacat agtcagattt atcctgaact tgcaaaaatg gaagagcaag
    13861 gaatcattca gcatcaagta gagatcacag gtgaaaaatt ggaaaagaaa gtttatgaat
    13921 taacagaaga agggaaggaa caattggcag agtggattca tacacccacc aatgaactac
    13981 cggttaatcg agacgaattt gttctgaaat tgtatttcgt caaagacgtg aatgatccgg
    14041 cattagtaga aattattcag cagcagcgtg accttcatga agaaaaacga cttcatctat
    14101 tagagcgaaa aaaaacgatc tttcctactg aaaaagaaaa acatgaaaat tacggacact
    14161 acctgatttt agcgcatgcg atcaatcggg aaacagaata tgcaaattgg ctaacagatg
    14221 tattagaaga aagtaaccga aaaaaataaa aaaatatccg aacagtgatg gagaattcct
    14281 ttctatatga aagaaacgca gatcaccgtt cggatattct tatgttcaaa caggcctttt
    14341 ttcaagtatt tatgtagcat ctacttatta aaaagcttgg tacttaggag attagtggcg
    14401 tttagagttc ttttaacaac tgttcgtagt cagctttttc atcgacagga aggagcttgt
    14461 aagttaattc gtctgtctcg ttgtcatgaa tgatgtacat cttagcattc tcttctttga
    14521 agttaccgat ttgtaaaatc gtatagcgtt cgtcgatcaa ttcgatatct ttgattgctt
    14581 ttgaaaaaac tttacggaca tggtgcattt tcttttggcg gatttctgcc ttttctgcag
    14641 cttttgacaa agtaaatccg tcatctaaat attttttgat cagttctact tttatgactg
    14701 taggtaaacg atattttcta ggacaattcg catcagcttc gatcgaacga atgaatccct
    14761 tttgttccca ataccttaat tgacgtggag acacacctac gatatcactt aattcactga
    14821 tgccaacaac caattgatca ttttccaaca aacgtttaag ggaagcccca accatttttg
    14881 tcactccttt tgtcctcttg cttcccttaa ttatatccgt attaacttat gtgtcaagta
    14941 ggttgacaaa tagcgaattt aggactaaag tattctagta gtttcagaaa aaattcagaa
    15001 agaaggagaa atatgagtaa caaccaaccc gtagatattt acggaaaacc atataatcgg
    15061 acacttttag ttgttgtctt attaattggt acattttgta ccgttttgaa tcagacctta
    15121 ttgacgacag cttttcctac attgatgaaa gctttcgata tttcagcgtc tgatgtgcaa
    15181 tggttaacga ctggtttctt gctagtcaac gggatcatga tcccaataac agcatggctg
    15241 atcaataaat tcagttcaag aaatttatat ctttctgcca tgacgatctt tttgatcgga
    15301 acgattactt gctttacagc acctaatttt agtacattac taatcggtcg tttgatccaa
    15361 gcttgcggtg tgggagtatc gatgccatta ttgcaaaata tcatgctatc tattttcccg
    15421 ccagaaaaaa gaggatcagc aatggggatg tcagggatcg ttattggact tgctcctgct
    15481 ttaggcccta cattatctgg ttatatcatt gataactacc attggcgtga cttgtttggt
    15541 atggtactgc caatcgttgt tcttgtcttg gttttagcat tcttcctaat gaaaagtgtt
    15601 attccattgt caaatcctag cattgatatt ttatccgcta ttttatcaac gattggattc
    15661 ggtagtttac tttacggatt ttctagtgta ggagatgacg gctggggaag cttgaaagta
    15721 attggtttct tagttgttgg tgtgattttc atcgccttgt tctcatggcg tcaattacat
    15781 ttggaacatc cattcttgga acttcgtgta ttcaaatcat ctacattcac gattgcagct
    15841 gttttagctg gtgtaacaaa tatggcgatg gtaggggcag aaatggtcgt accattgtat
    15901 attcaaaata ttcgtggaga atcagcattc cattctggct tgatgttgtt gccgggtgca
    15961 ttgatcatgg gggctatgat gcctgtgacg ggtgcgattt tcgataaata cggcgcgaaa
    16021 cgtttagcca tcacagggat gttcattttg acagcggcaa ctgcaccatt tgctttcttg
    16081 acaaaaacga ctccagtttt atatatcgtg atcctttatg cgatccgtat gtttgggatc
    16141 tccatggtca tgatgccggt aacgacttct ggtatgaatg cattgccaaa taacttgatc
    16201 agtcatggga cagcggtaaa taatacattc cgtcaaatcg caagctcgat tggtacagct
    16261 attttgatca gtgtgttgac gaatgtgaca aaagcaaata tcccaagcaa atctgtattg
    16321 gataatacgc cattagctta taaagatcag gcaatcaatg ccacactgtc aggttaccat
    16381 gccgcgttta tcgtagcgat catctttggg attcttggct ttattattgc ctttttattg
    16441 aagaaaaaag aacctgttct aatgaaagcg ggggataatg catgattatt ggagttttga
    16501 ttgtcagctt gcttgctttt gctttaacga acgtgttcgc taaaaaaaca tggcaaacct
    16561 ttttatcttt gattttcgga ctaatcttcg tcgcttcact aagtttgatc gtcgctaatt
    16621 tgtccaatca ctttggaatg gaaaaagtaa cggaaacaaa aacagaaaaa attgtttcca
    16681 gtgctgattc ccaaggagca gatatgcttt tgtataaagc tttagggaat ggaaaagaaa
    16741 aagtgtatct ttaccgaaca aatgaaaaac aagaaaaacc aaaagcaact ggtacggata
    16801 acgaaacaaa taaagtagaa aagacagacg gcgatgctga aaaagtgacg aaaactactt
    16861 attgggaata caaaaacgac atgtataaat tctggttcaa tattgctgat aacaatcacg
    16921 aatatgacag ccgagtgaat acattcaaaa tcccagagac atgggtagaa ttaagtacgg
    16981 accaagcagc caagttagct gaattagtga agaaacagca aagtacgatg gaaagtgaag
    17041 caaaagctta tgttcaagac ggtatggtaa aagcaatgac tgaaaatcca aaaatgagca
    17101 aagcagagca agaacaacgt acgaaagcct tagctgctga attccaacaa caagcattcg
    17161 caaaattagt gaaagaagca aaaggcgaat aatattttga acaccatgta ggaggttgtg
    17221 aaa
//
LOCUS       DASHXG010000054        17007 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.055, whole genome shotgun sequence.
ACCESSION   DASHXG010000054 DASHXG010000000
VERSION     DASHXG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.055"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..126)
                     /locus_tag="U2R59_002165"
     CDS             complement(<1..126)
                     /locus_tag="U2R59_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HEM8966519.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="U2R59_002166"
     CDS             complement(230..541)
                     /locus_tag="U2R59_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8966520.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="U2R59_002167"
     CDS             complement(543..740)
                     /locus_tag="U2R59_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HEM8966521.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="U2R59_002168"
     CDS             complement(1134..2861)
                     /locus_tag="U2R59_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEM8966522.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="U2R59_002169"
     CDS             complement(2854..4047)
                     /locus_tag="U2R59_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEM8966523.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="U2R59_002170"
     CDS             complement(4234..4878)
                     /locus_tag="U2R59_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966524.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="U2R59_002171"
     CDS             complement(4972..5106)
                     /locus_tag="U2R59_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HEM8966525.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="U2R59_002172"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="U2R59_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HEM8966526.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="U2R59_002173"
     CDS             complement(7237..7710)
                     /locus_tag="U2R59_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HEM8966527.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="U2R59_002174"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="U2R59_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEM8966528.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="U2R59_002175"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="U2R59_002175"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEM8966529.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="U2R59_002176"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="U2R59_002176"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEM8966530.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="U2R59_002177"
     CDS             complement(11757..12896)
                     /locus_tag="U2R59_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEM8966531.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="U2R59_002178"
     CDS             complement(13205..13918)
                     /locus_tag="U2R59_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEM8966532.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="U2R59_002179"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="U2R59_002179"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEM8966533.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="U2R59_002180"
     CDS             15107..16639
                     /locus_tag="U2R59_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEM8966534.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="U2R59_002181"
     CDS             complement(16830..>17007)
                     /locus_tag="U2R59_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8966535.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DASHXG010000055        16075 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.056, whole genome shotgun sequence.
ACCESSION   DASHXG010000055 DASHXG010000000
VERSION     DASHXG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.056"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="U2R59_002182"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="U2R59_002182"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="U2R59_002183"
     CDS             complement(227..697)
                     /locus_tag="U2R59_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEM8966536.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="U2R59_002184"
     CDS             complement(856..1314)
                     /locus_tag="U2R59_002184"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEM8966537.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2630)
                     /locus_tag="U2R59_002185"
     CDS             complement(1485..2630)
                     /locus_tag="U2R59_002185"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEM8966538.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2643..3560)
                     /locus_tag="U2R59_002186"
     CDS             complement(2643..3560)
                     /locus_tag="U2R59_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HEM8966539.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3988..4551
                     /gene="efp"
                     /locus_tag="U2R59_002187"
     CDS             3988..4551
                     /gene="efp"
                     /locus_tag="U2R59_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEM8966540.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4652..4822
                     /locus_tag="U2R59_002188"
     CDS             4652..4822
                     /locus_tag="U2R59_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966541.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            5037..6296
                     /gene="lysA"
                     /locus_tag="U2R59_002189"
     CDS             5037..6296
                     /gene="lysA"
                     /locus_tag="U2R59_002189"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEM8966542.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6283..7083
                     /gene="dapF"
                     /locus_tag="U2R59_002190"
     CDS             6283..7083
                     /gene="dapF"
                     /locus_tag="U2R59_002190"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HEM8966543.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            7086..7967
                     /locus_tag="U2R59_002191"
     CDS             7086..7967
                     /locus_tag="U2R59_002191"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEM8966544.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7964..8680
                     /locus_tag="U2R59_002192"
     CDS             7964..8680
                     /locus_tag="U2R59_002192"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEM8966545.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8686..9381
                     /gene="dapD"
                     /locus_tag="U2R59_002193"
     CDS             8686..9381
                     /gene="dapD"
                     /locus_tag="U2R59_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEM8966546.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9397..10398
                     /locus_tag="U2R59_002194"
     CDS             9397..10398
                     /locus_tag="U2R59_002194"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEM8966547.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10395..11756
                     /locus_tag="U2R59_002195"
     CDS             10395..11756
                     /locus_tag="U2R59_002195"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEM8966548.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11716..12867
                     /locus_tag="U2R59_002196"
     CDS             11716..12867
                     /locus_tag="U2R59_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HEM8966549.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12842..14011
                     /locus_tag="U2R59_002197"
     CDS             12842..14011
                     /locus_tag="U2R59_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8966550.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14186..15565
                     /locus_tag="U2R59_002198"
     CDS             14186..15565
                     /locus_tag="U2R59_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8966551.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15846..16075
                     /locus_tag="U2R59_002199"
                     /pseudo
     CDS             15846..16075
                     /locus_tag="U2R59_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5257 a         2840 c         3427 g         4551 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat ctttatggtt agaagtcact aaaccagcta ctacatcgct gtgtccgcct
     2041 agatatttgg taccgctatg gacaacgata tcagaaccga gatctaaagg tctttgaaaa
     2101 taaggagtag caaatgtatt gtcagcaata actatcaatc catgttgatg agccagagtg
     2161 gcactttttt ctaaatcagt aatctttaga agcggattgc taggtgtttc aagataaagt
     2221 gcttttgtat tgggtttgat ggattgttct attttatcaa gattactcgt atctatgatc
     2281 gtgtactcga gaccattttt agtaagaact ttgtcaaata gacggaatgt tcctccatag
     2341 acatcatctc ctaataagat atgatcgcca gcttgaaaaa gagaaaaaac ggcatgaatc
     2401 ccagaaagac cagaagaaaa agcgaatcct cgaacaccgc cttccaaatc agcaatcagt
     2461 tcttccaatg caaaacgagt aggattacca gatcttgaat attcatattg tttaggctgg
     2521 ccgacgccat cttgccgata agtggatgtt tgataaatag gtacactaac agctcctgtt
     2581 gtgggatctt cactgatgcc tccgtggatc aattttgttt gaatgtgcat gtttctttcc
     2641 tcctataagt aaatgttttt tgataaatag cggtctgctg cgtctggaaa aatcgtaacg
     2701 acacgatgac caggtggtaa acgacgaatt tctcttaatg ctgctgcaaa agccgcacca
     2761 ctcgaacttc caactaatag tccttgttct cgtgctaact gcctagtata gttaaaccct
     2821 tctacatcag agattgtctc gatctgattg attgaaaggg gagaaagaaa cggcggaatg
     2881 aattctacac cgataccctc aatttcgtga ggggctggat caccaccatt taacacagag
     2941 ccctctggtt ctacaccgat tattcgaatg tcgggatatt tttctttcaa aaaggtagaa
     3001 gttccagcaa aggttccacc actcccaatt cctgctacaa aactatggat attttctttg
     3061 atttcatgaa agatttctgg ccctaacgta tgatagtaag cagcaggatt atctttattt
     3121 tcaaattgaa gaggcagata gctgtttgat atctcctctg caagtttttt acttttgctg
     3181 atggcaccga tgattccttg ctcactagga gaatggatga tctttgctcc caatgctttc
     3241 atcaattgtt gtttttctaa gctaaacttc tctggaacaa caaaaaccgt tcttaatttg
     3301 tatgtgagtg cggccagagc gatcccaatt cctgtatttc cggcagttgg ttcgatgatc
     3361 gtcgtttttt cattgatttt tccttgggca aatccttctt tgatcaaata actgcccaat
     3421 ctatctttga tacttcctcc aggatttaaa tattctagtt ttgcataaat agcagaacct
     3481 ttaggcatag aatagtgctg attgtcaaag cgataaagcg gtgtggaacc aatagcttct
     3541 gtaattgtcg agataatcat gtgggcctcc taaaaaaaga taataaaaaa aggagctgac
     3601 tattaaatca gctccttgaa agacatagag aaaaattgag tagataaaaa gataagttac
     3661 ctggtactca ttctatgaag ggcaattaat agacatgaca aatagtatgc tgcttttatg
     3721 caccatacaa cagcaacgat tcaattgttt ttggttgctg actgtcatgt gtatccctcc
     3781 aagtaaaatt tttattaacg atagcatgaa aaaaaataaa agtcaaaggc ttgaaagaaa
     3841 aaaatatttc gatagcatcg tttacccgtg tttatttttc tgacaaatag gcatgagacc
     3901 ttaaaagata gagaatactc tagttttctg gccggttgtc tgatacaata aagttgatta
     3961 tgataaagaa aagaaggagc aaaaataatg atctcagcaa gtgatttaag agccggtatg
     4021 actttcgtac aagacggcaa actgattaaa gttctggatg caagccacca taaacctggt
     4081 aaaggaaata cagttatgcg tatgaaactg aaagatgtcc gttcaggtgc aacatacgac
     4141 acaacgttca gaccagaaga aaaatttgaa aaagcacata tcgacacaaa acctgtacaa
     4201 tatttgtaca cgatggatga tacagctttc ttcatggatt tggaaacata tgagcaatat
     4261 gaaattcctg tagaaacagt agaagaagaa atgaaatata tcctagaaaa catggaagta
     4321 aaaatccaat ttttcggtag cgaagtcatc ggcgttcaat taccaacaac tgtcgtatta
     4381 cgtgttgtgg aaacacaacc ttccatcaaa ggtgcaacag tcactggttc aggtaagcca
     4441 gcgacaatgg aaactggctt agtagtcaat gttcctgact tcatcgaaac agatgaattg
     4501 ttggaaatca atacagcaga aggttcttat gtaaaacgtg cgtcaaaata attcgctaac
     4561 ggattgataa gaatttgaaa acagagcttg acctcttgaa aggcagatca tcggatctgc
     4621 ctttcaagag gttttttgtg gaatcagcaa attgaaaaat aaaaaagtat ttgattttat
     4681 ttatattttg aaagatgaat ggcaaaagct agagaaagaa aaaactgcac ttatttatga
     4741 agaaattgaa atgattcata aaattgaaaa tatccgaact attccgaact atattgaagc
     4801 gaaaatattt tttcatcact aaatagtgtt gaatttatgt ttttatgtat aaatagcttc
     4861 taatagttcg ggtattttgt ttttataacc atttttattc ttatttttaa aaaaatattt
     4921 cgaaatatac tagacaattc agaaaatttt gtttaatatt attccaataa aattcaaatc
     4981 tttatcaaat gaaattccaa taaaaacgga aaaaaagtga aaagaggaat gaaaaaatga
     5041 cagaattgat aattggcgga gtcacagcaa gcacattggc agaaaagtat aagacacctc
     5101 tgtatgtgta tgatgaagaa aagatgagac aaacgatgct gtcattcaag cgaggctttg
     5161 tatcgaaacg ttttgataca aaagtgcttt acgcctctaa agcattccaa acgattgaga
     5221 tgctgcattt agttcgtgaa tatggattcg ggctagatgt tgtcagtggt ggggaaatct
     5281 ataccgcttt gcaagctgat tttcctagag atactatcta cttccatggt aacaacaaga
     5341 cgccagagga actgatctat gcacttgaaa atgatttgtt gcatattgtt gccgataatt
     5401 tgatggaagt tgaattatta gcagaattaa gccaacgcta tttaaaaaaa atctgtatca
     5461 tgcttcggtt gaatgtcgga gtagaagcac atactcatga atatatcgtc actgcgcata
     5521 ttgattcaaa attcggcatg agctatgaaa gtaaagagtg ccaacaagcc cttcagttga
     5581 taaaagaaag cagctatcta gagttagaag gatttcatgc tcatatcggg tcacaaattt
     5641 ttgatgttac tgcttggtta gctgaaatcg acaaattgac gaattactta accgattttg
     5701 accaacctct ttccttgaat cttggcggag ggtttgggat tcgttataca caaaatgatc
     5761 agccgatccc agtcgaagag gcactaaaaa aactgattga atatacggaa gaagctttgg
     5821 aaaaacgaaa actgaccatt cgtcaattac tgatcgaacc gggtagaagt attgttggag
     5881 aagctggtac aacactatac acgattggtt tcatcaaaaa gacaccacat aaaaaatatt
     5941 actttgtaga tggcgggatg acagataata tccgtccagc tctgtatcag gcagaatacg
     6001 attgtgattt agcagcaaaa ctgtcggaag aaaaaacaga gaaagtgacg attgcaggaa
     6061 aaatgtgtga atcaggcgat gtggtaatta aagaagctta tttgccgaaa gcagaatcgg
     6121 gtgatctttt agctgtttat tccacgggag cttatggata ctcgatgagc agcaactaca
     6181 atcgagcgac acgaccagca gttgtttttg tcaataatgg ccaatcaaga ctgattgttc
     6241 gcagacaagc attttctgat ctactaaggg gggaagtttc ctatgatcct tcataaatat
     6301 aatggctgcg gaaatgattt tatcttatta gattacgcag aagacacaga ttatagtcaa
     6361 ttagccgctt ctttatgcac aaaagaaaaa tatgatatag acggattgat cgccgtaaaa
     6421 atcgatccgt tggaaatgat ctattacaac aaagatggca gccgcgcgcc gatgtgcgga
     6481 aatggcattc gctgttttgc tcgatacgta aatgatcaga acatgatgaa tgaacaggaa
     6541 ttcaacgtag agacattagc aggcacaaga aaaattacgg tgttggatcc ctcacctttt
     6601 tattgcagcg tagatatggg agtgccagat gattctccgg aaaaaatcaa agctaatcaa
     6661 acttatccaa taaaaaacca ggaaatagag atcaatggtg aaaaagtaac gatcactagt
     6721 ttatttttag gaacgattca taccgttgtt tttgttgaaa atgcgcgtga ggaagtctgg
     6781 agaaaaagag gtgaactgat ctgtcatcat cctttgttca aagaaaaaac caatgtcaac
     6841 tttgtagaag tagtcaatga acaagaattg atcgtccgta cctatgaaag aggagtaggt
     6901 tggacacttg cttgcggtac aggttgctgt gcctcttatg tggttgctaa ggaaactggg
     6961 aaaatttcag cagatcaggt agttgttcac ttggaacaag gagacttgat gatctctggt
     7021 gaggatgcga tacaaatggc tggcccagca gttcatgaat ggacaagaat attggaggaa
     7081 tgaagatgat aaaaggttcg atcgtggcgc tgatcacgcc gatgaatgaa gagggatcag
     7141 tagattatgc tggtttggaa aaattgatcc aattccattt agatgaacaa acagatggat
     7201 tattagtttt aggtacaaca ggagaatctt ctacgctcac acaatctgag gaggagcaga
     7261 tccttcaact gacagtaaag aaagtggctg gccgtgtgcc ggtgattgca ggagctggaa
     7321 cgaataatac gaaagaaacg attgaaaaag cgaagcattt tgcttctttg ggggcagacg
     7381 cacttttggt catcacccct tactacaaca aaacaagtga tgcaggacta gctgctcatt
     7441 ttacagcaat tgcagaagcc tcaccgattc cgcttatttt gtataatgtt ccttctagaa
     7501 caggcatgtc gattccaatc catgtattag taaatttagc agaacatcct aatatcattg
     7561 gtttgaaaga agcctcagga gatatggctt atgtgatgga tgccgctcgg ttgattggag
     7621 aagaattctt cctttacagt ggaaatgatg atttgatcct accagtaatg agtgtaggag
     7681 gaagcggtgt aataagtgta tgggcgaata tccaacctaa aatagtccat gaattagtaa
     7741 aagatacgca ggacggaaga tggcagcaag caaaagaaaa gcaattaaat gcacttgaac
     7801 tgatccatgc cttgttcagt gagaccaatc ctattcctgt caaagcagcc atgtcattat
     7861 tagacttacc ttccggacct ctacgcctgc ctttagtttc tctttcaaaa gagaaaaaga
     7921 aacaattagc tcagcttttg ttaaaagaaa ggacggttga aaaatgaaaa tcggactgat
     7981 tggcagtgga cagatgggaa atagagtcga agaagttgca caagaaagag gagatacggt
     8041 ccttctttta cggacggcac ctaaagaagc aactacgctt gcttttacgg aactgccaga
     8101 actgcttatt gatttttctc atccagataa tttagagaaa atcctttcgt atagcttatc
     8161 atatcaactt ccgttagtca ttggcacgac aggttataca caatcacagt tccaagaaat
     8221 aaaagaacat gccaaacatg tacctgtgat gtatagtgct aatttttcgt tcggcatcat
     8281 ggtgatgaat caactaatca agcaagcagc tgcaatgttg caaggctggc agatcgaact
     8341 gattgaaaaa catcatagtc gtaaaaaaga tgcaccatct ggtactgcaa atatgctgct
     8401 tcaaacaatc caagaagtgc aaaagctgca gcccgtatac aactggcaag ggaaaaaaag
     8461 agaagaaaac caaattggtg tacacagtat tcgtgcaggt tctttacctg gtgaacatga
     8521 tgtattgttt gctgctactg atgaaatatt tacgatcaaa catgaatctt tttctaatcg
     8581 aatctttgct gcaggcgcag tagaagcagc ggactggttg aaagatcagt caccaggtta
     8641 ttacaaatta gaagatttat taatggacaa aggggtgtaa aaaacgtgga agctcaagaa
     8701 atcatccgct acattcaaac ggcatctaaa aagacgcctg tgaaagtcta tctgaatgta
     8761 accgagccaa tcgaatttaa agaaagtaaa gtttttggtg aaggaagcag cttcgttgtt
     8821 tttggtgact atgagacgat tgctccggtt ttagaagctg aatcagaaaa aatcattgaa
     8881 atcgaaatcg aaactgctgc aagatacagc gcagttcctt tgctagatat taaaaaaatt
     8941 aatgctcgta tcgaaccagg tgctattatc agagatcaag tgtcaatcgg caacaatgcc
     9001 gtgatcatga tgggagcgat tatcaatatt ggtgcagtaa tcggtgaaaa cacgatgatt
     9061 gatatgggtg ctgtcttagg tggacgagcg acagtgggca aaaactgcca tattggtgca
     9121 ggagctgtct tagcaggtgt gatcgaacca gcatcggcca aaccggttat cgtagaagac
     9181 ggcgtactgg taggtgcgaa tgcagtgatt gttgaaggtg tccatatcgg aaaagatgca
     9241 gtcgtggcag caggagcagt ggttttagaa gatgtggcag cagaaactgt tgtcggtgga
     9301 atacctgcac gtgtattaaa aataagtgat gatcagacaa aagaaaatac agcattgatt
     9361 gctgcgttac gcgaattata gaggagatgg agaaaaatgc gcgaaataga tacctgtatt
     9421 gtgggggcaa ccggattagt cggccaaacg atgctcaaag tgttagaaga atatgatttt
     9481 ccagtaggac gattgaaatt attagcttca aaacgttcag ccggtaaagt ttgtgtattc
     9541 aagaaaaaga aacacactgt acaggaattg acagaaactt catttgaagg atatgattta
     9601 gcgctatttt ctgcaggtgc ttctgtatcc aaagagtttg cgccaatcgc acgaagtcag
     9661 ggactatttg tcatagataa ttcctcagca tggcgggaag attcggatat tccattaatc
     9721 gttccagagg tcaatctgga agactataca ttgaatcggc tgattgcaaa tccaaattgt
     9781 tcaaccattc aagcggtact tccgcttaaa gctttacaag aagcctttgg tatccagcga
     9841 gtcaattatt cgacctatca agcagtttct ggttccgggc aaaaaggcat tgaagatctt
     9901 catcgtacgc aaaatgacga ggaaccagtt ttgtatcctt ataatattag ccaaacggtg
     9961 attccggaaa tcgatcagcc tttggaaaat gggtatacaa aagaagaaca gaaaatgata
    10021 aatgagaccc gtaagattct gcatcagcct gctttgccag tatcagcaac ctgcgtacgt
    10081 gtgccaatcg aaaatggaca tggagtctct gtggcagttc aactgcaaaa agagtttacg
    10141 acggaagaaa ttagagagtg tctcagccag tttccaggga ttcaattaga agatgatcta
    10201 gcagcacata aatatccgac gagcattctt gctagaggaa cagatatggt ttatgttggg
    10261 aggatcagaa aagacacttc tttagagaac ggattgttgt tctatacgac tgccgataac
    10321 atacgcaaag gagccgctgc gaatgccgta cagattgctg cagctttaat gcagaaaata
    10381 gcggaggtgg caagatgagt aatacgctga aagtagcgaa attcggcgga acatcgatgt
    10441 ctcatgaaga gcaattcaaa aaagtccgta caattgttct ttcagatccc aatcgccaag
    10501 tgatcgttgt ttctgcttta ggcaaacgta cgtcagatga tgacaaagta acagacttac
    10561 tttatttgat ttatgcttac cttcagcatc atgttgattg gacacccctt tggaaaagga
    10621 tttgtgatcg tttcattcaa gtaagagatg ttcttgccct gcagttacct attgaagatg
    10681 aactagcacg catacagaaa caactggaag acgaaaagat aactgaagat tatttagtaa
    10741 gtagaggtga atatctgact gctcaactga tggctgagta tcttggttac cagtttattg
    10801 acgcaaaaga cctgattttc tttgactatg atgggaaaat cgatcaggaa aaaacagcac
    10861 aggaaatcac aaaagcattt aaaagatatc cgaaaatggt tgttccaggg ttttacgggg
    10921 cgaaccctgc aggaaaagaa aaattattgg gccgtggggg aagcgacatt accggcgcga
    10981 tactggcgaa gatgttgcaa gcggaaagtt atgagaattg gacggatgtt tcaggaatca
    11041 tgatggctga tccgcgaatc atcgatcatc ctaaaatcat cgaggaaatc tcttttagag
    11101 aactgagaga gatggcttat atgggggcta acgttcttca tgaagcagct gttttcccag
    11161 ttcaagaggc tgatatcccc atccaaataa aaaataccaa tgatcctttc gctcaaggga
    11221 caaaaatatc gaatcacgaa atagaaaagg aaaatggact gacaggaata gctggacgca
    11281 aggattttct ttccatcact ttattcaaac gtcatatgtc cgatgaaatc gggtttatct
    11341 ggaaagcaat gagcattttt gctaaacatg agatatcaat cgaacatatt ccttcaggga
    11401 tcgacaatat cggagtgatc gtctcagcag aagcgattgc cgataagtta tttctcatca
    11461 cgaaagaatt aaaagaaaca cttggcgtgg aagaaatcgt cgtgatcgaa gacttagctt
    11521 tgatctctgt cgttgggggt ccgcataaag aattgattgg attatctggg aaagtgttat
    11581 cgatattgaa caaattagaa attcgcacat cgatcttatc acaaggagca caggagttga
    11641 atctgatcat cggtgtaccg aataatcaat atgaaacagt agtgaagggt atctatgaag
    11701 ggatggtgaa tacggatgct gaaagaatat cgaatggcac tccatcaaat tcctgaaatc
    11761 gggtttcatg aattcaagac aaaaaaatat ttatatgaac aagtaaaaaa cagcgaggcc
    11821 gttatccatg aaatcggcga aacaggacta ctcctttatt ttgataatca gcaagaagaa
    11881 acgattgctt ttcgaacaga tatcgatgca ctgccagtca aagaagaaac gaatctctct
    11941 tttgcttcta agcatgaagg ttatatgcat gcatgtggtc atgacggaca tatggcgatg
    12001 cttttagggt tgactgactt tataactaaa cacattgagg atcttattta taatgtagta
    12061 ctgatctatc agccatcaga agaaatttcc ggtggcgcac aaagcgttat tcagtcagga
    12121 ttgttggata aatatgaagt acaagcaata tttggctttc atctatggcc tggactagct
    12181 aagggagaag ttttctctcg accaggacct ttgatggcac aaagcagtga aacagacatt
    12241 atcattaaag gccagtctgc acatattgct tctagtgaaa aaggaatcga tagtctggag
    12301 gcagctgtac gatttttgaa gaatgtttat gattttgacc ggcaattacc ggcagagtgg
    12361 aatcatctaa tgaaatttgg ccaaatccaa ggtggaacga tccgaaatgt tttagctgga
    12421 gaagttattg tatccggaag tatccgttct tacagttcag atatgcaaaa ttatttgaag
    12481 aggggattag accatttagc agaacagttt cactctacag ctactatttc ttttcgctat
    12541 aatgacggct atccagctgt aatcaaccat agaggcttat atgcagcact gttagattca
    12601 aacaaactac atgaattaga tgctccagtt cttcaagccg aagattttgg catatatacg
    12661 caacaatatc catgtgtatt tttcttttta ggtgtcggtg atacccctgc tttacatgat
    12721 ccgacgttcg attttgatat ggatgtttta gaaaatggtg tagaatggta caaaacgatt
    12781 ctttttacag aaaatcttct tgtaaaaatc gatagcagtt caaaagagga gcgagtaaat
    12841 aatgatgaat ttatccaatc gatttagtcc taggctttct agaatagaag tatcaaaaat
    12901 acgacaattc gatcagcaaa tatcgtcgat accagatgtg atcaaactca ccctgggaga
    12961 accggatttt ccaactcctg aacatgtcaa gcaagcagga atagcagcga ttgaagaaga
    13021 cttttctcac tataccggaa tgagaggatt agaggaactg cgggaagcgg cttgtatatt
    13081 tcagcaacag cgttatggat taacttatga tccgcaaacg gaagttttga cgacagttgg
    13141 tgcaacggaa gcgattgcct ctgcgttgtt atctgttttg gaagaaggag acaaggttct
    13201 tattccagcg cctgcttatt caggatatca gccattagtg gaactagctg gtgctgaatt
    13261 gatcccgata gatacttctg acacagggtt tgtctgtcag ccggaacaat ttgaacgagc
    13321 atttgaacaa tatggatcag ctgtcaaagc agtcatttta aactatccta acaatcctac
    13381 tgggacgaca ttgtctgcaa aacaattgaa agcaatcgct gaggttttaa aaaaatatcc
    13441 ggtatttgtt ataagtgatg aagtatatgc tgaattgact tatagtggaa cgcatatgtc
    13501 catagctact tatcttccag aacaaacaat cgtgataagc gggttatcca agtcacatgc
    13561 gatgactggt tggcgagtgg gctttatttt tgctcaaaaa gcccttattg acgaactaat
    13621 taaagtccat caatatctgg tgactgccgc tacaacgatg tcgcaaaaag ctgcggctga
    13681 agcgctaata aatggggtga aagatagcga gaatatgaaa gagcaatatc aaacacgaag
    13741 agactatctg gtccagcaat tggcgccttt aggatttgaa gtgacccagc caaacggtgc
    13801 attttacttg ttttgcaaac tcccagctgc cattcaaact gactcttggc agttttgtgt
    13861 agaattagcg gaacaggcaa aagttgcgtg tatcccagga attgcatttg gcccagaagg
    13921 agaaggttat atccggattt cttatgctag cagcatggaa aaattacatg aggcctgcaa
    13981 acggatcaaa gactttttaa cagaacagtg attcatagat tttatcaaaa aaacaatcgt
    14041 taattttgcg gtatattctg caaggagacg attgtttttt aaatttagtt caaatgaacg
    14101 cgtttctttt gattcataac taatgtaatg ttaagtttaa attgtttaga atgattttaa
    14161 aagaatattc aaggaggttt catcaatgga aaaaatcaaa gttgtcattg taggtgcatc
    14221 tcatggaggg catcaatcga tcttggaact attgacacga tacggtgaaa atgtagatat
    14281 cacgctattt gaagcaggag actatatttc cttcatgtca tgtggtatgg agctgtattt
    14341 agaagacaag gtaacagatg taaatgatgt acgtaatttc agaccagaaa actttccgca
    14401 atccaatgtt catattttaa ataatcacga agtaaaaacg atcgatgccg ataaaaaaac
    14461 agtaacggtt actagcgcat cagataacga aacaaaagaa tatccttatg acaaattgat
    14521 tttgagttct ggtgtcaaac caaacaatct gccagtacca ggagcagatc tagaaaatgt
    14581 ctacttgatg cgtggataca attgggcaac caaaatcaaa gaaaaattaa atgatccggc
    14641 tattaaaaaa atcgctgtcg taggtgcggg ttacattggg atcgaagcag cagaagcaag
    14701 ccgaaaagct gggaaagaag tcgtattgct tgatgtgatc gatagacctt taggcactta
    14761 tttagatgct gagatgacag atattttaga acaacaccta aatgaaaacg gtattgaagt
    14821 tttgacaaat gcaaaaatcg aagcttttac tggtaacgga aaagttgagg caatcaaaac
    14881 aagtgaaaaa gaaatcccag cagatctagt cattcaagct gccggtgtga aggcaaatac
    14941 agaatggtta aaagggatcg tcgacttaga tgaacgtggc tggatccaaa caaatgaata
    15001 cttgcaaacg aatcttccag atgtgtatgc agtaggagat gctacacttg cttattctat
    15061 cccagcacgc aaaaaaatgc cgatcgcttt agcgactgtt gcacgtagag aagcacgtta
    15121 tgtagtaaaa catctttttg aagaagtacc aaacaaaccg ttcggcggag tcgtaggttc
    15181 ctctgcatta agtgtctttg actatcattt tgcagcaagc ggattgaata gctttacagc
    15241 agcaaaagca ggagtagatg tacgagtgtc ttattatgaa gatacgttac gaccaaaata
    15301 tgtaccagaa gaacaaggaa atccaaaagt gtccatccaa ttattctcgg atccaatgac
    15361 ccatcaattg ctaggaggag cagtattatc tacctatgat gttacaggtc aaggaaatgt
    15421 attggcacta gcgatccaaa acaaactgac tttagaagaa ctagcagaag ctgacttctt
    15481 cttccagcca ggctttgacc gacaatggag catgttgaat ctagccgctc aacaagcgtt
    15541 aggagaagaa ccatttgtag aataagaaaa cgaaatattt gaaaagaggt tgtgaaaaag
    15601 ctgccttgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttaactt
    15661 ggctggactt attaccgcag atgcaagctt ttgaacaccg tttattttca aaaaagggac
    15721 tgtgacacga tttgtgtacc gacccccaaa agttagacca aaaaatctaa cttttggagg
    15781 tcggtatttt ttatggttaa atatactttt gaacttaaat taaagatcgt tcatgattat
    15841 ttggatggca aaggcgattg gaccgtaaaa atccagatca agagattgaa gcggaaatgc
    15901 ttaaaattcg ggagaagcac aaggattatg gctgtttacg gatgaccaat gaactaagaa
    15961 accgcggttt ctctatcaat aaaaagaaag ttcagcgctt gatcaagaag ctaggaataa
    16021 aagtaacggc atacacgcgt aaatcacgtc gctacaattc ttatcgagga aaagt
//
LOCUS       DASHXG010000056        15801 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.057, whole genome shotgun sequence.
ACCESSION   DASHXG010000056 DASHXG010000000
VERSION     DASHXG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.057"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(7..1374)
                     /gene="nhaC"
                     /locus_tag="U2R59_002200"
     CDS             complement(7..1374)
                     /gene="nhaC"
                     /locus_tag="U2R59_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HEM8966552.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1483..2904)
                     /locus_tag="U2R59_002201"
     CDS             complement(1483..2904)
                     /locus_tag="U2R59_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8966553.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(3147..5024)
                     /gene="tdc"
                     /locus_tag="U2R59_002202"
     CDS             complement(3147..5024)
                     /gene="tdc"
                     /locus_tag="U2R59_002202"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HEM8966554.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASDA
                     K"
     gene            complement(5315..6571)
                     /locus_tag="U2R59_002203"
     CDS             complement(5315..6571)
                     /locus_tag="U2R59_002203"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEM8966555.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6683..6888)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7151..8452
                     /locus_tag="U2R59_002204"
     CDS             7151..8452
                     /locus_tag="U2R59_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEM8966556.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8521..9120)
                     /locus_tag="U2R59_002205"
     CDS             complement(8521..9120)
                     /locus_tag="U2R59_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8966557.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9374..10255
                     /locus_tag="U2R59_002206"
     CDS             9374..10255
                     /locus_tag="U2R59_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966558.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10268..11878
                     /locus_tag="U2R59_002207"
     CDS             10268..11878
                     /locus_tag="U2R59_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HEM8966559.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(11955..12614)
                     /locus_tag="U2R59_002208"
     CDS             complement(11955..12614)
                     /locus_tag="U2R59_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8966560.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(12897..13562)
                     /locus_tag="U2R59_002209"
     CDS             complement(12897..13562)
                     /locus_tag="U2R59_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HEM8966561.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(13709..14314)
                     /gene="dhaL"
                     /locus_tag="U2R59_002210"
     CDS             complement(13709..14314)
                     /gene="dhaL"
                     /locus_tag="U2R59_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HEM8966562.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(14342..15352)
                     /gene="dhaK"
                     /locus_tag="U2R59_002211"
     CDS             complement(14342..15352)
                     /gene="dhaK"
                     /locus_tag="U2R59_002211"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HEM8966563.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(15327..15773)
                     /gene="dhaM"
                     /locus_tag="U2R59_002212"
     CDS             complement(15327..15773)
                     /gene="dhaM"
                     /locus_tag="U2R59_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEM8966564.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
BASE COUNT         4525 a         3300 c         2873 g         5103 t
ORIGIN      
        1 cttccttcaa ttttttacac gtcgacgatt caataaaaaa ccgcctaata ttgtaaagac
       61 aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc aacgcgctaa ctttcatcgt
      121 tcccataatg aatgtgccgc tgactcccca cggtacgaga gaattgacgg tcgcacctga
      181 atccgctagt gttcgtgtca aataggtttt tgataagcca acgtcatcaa aagaacgctt
      241 gaatgtttct cctggaagaa tgatggacag atactgttct ccaacgatca gattgattcc
      301 gatacagctc aaggcagtaa acccgactaa acgagaaggt cggtccatct tttcttttaa
      361 ttcttgaacg atggtatcaa cgatcagata tttgatcagt aacccaccta atgccaatgc
      421 aagtaaaatc aaactagcag aacctaacat actcatgatc ccgcctcgag aaagcagttc
      481 atctagcttt ggatcaggtg tatttgcgac ataaccattc atcaagatgt ctgctgcttt
      541 tccgaccgtc aaacttttct catggataaa agaaagaacg agagcagctg tcgatcccgc
      601 tagtaatgta gggatagccg gaattttttt gattgccccc ccaaataaaa taactagtgg
      661 aatcaatgtc caaggagaga tccaaaagct cgctttcatg ttttggatca tttcattgat
      721 actagctaga tcggctgaat gactgttatg tcctaatatc gtataaaaaa tcaacgaaag
      781 gacgaatgct gggaaatccg tataacgcat accagcgata tgttcgaata gattaactcc
      841 tccaataccc gctgccaagt tggtcgtatc tgataaaggc gagcagttat tccctaaaaa
      901 ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg aatccaagta aatgaccgat
      961 ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat gaactgccga cagtcactcc
     1021 gacaattgca caaacaagaa atgctgtcgg taaaaagaaa cgcacagaaa caagtttaaa
     1081 tccataaacc ataatcgtag ggatggttcc agataaaatc catgaagcaa ctaagacacc
     1141 aatcaaaaga aaaatcagga ttggaatgat ccctggagtg attcctttga tgatcccgtc
     1201 atggatctca tcccatgtga actttttaaa tctgccataa aacaacaaac acatgaaagc
     1261 tgcaaggatc gggatatgtg gcgagagctg gaatccgatg atcagtactc ctaggagtgc
     1321 caacaacacg atcaatacag cgatactttc ttttaaagaa atatttttat tcatcgtcga
     1381 tctcctattt caaatgaaaa ggccctgcca tgaaaaaact attcacttgg caggacctcc
     1441 tactaaatca gcgacaaaac gtcggctgaa agacttattt ttttattttt cttctaaact
     1501 tttttctacc tcaatccccc aagaatcttt cttgaagtga ttgatgatca atggaataac
     1561 gaacatgacc actgtgatag ctgctactaa taatgcatca ctcaatgtcg ctgtacctaa
     1621 tgtagcaaat acgacaacga tgatagagaa gatcagcatg cagctgacta cccaagctaa
     1681 tccgtttccg tttttaccaa ttcggtaagg acgttcgaat tctggatgtt tcttacgcat
     1741 tttaagcaat gaaacagcaa tcaaaatgta cacgatacaa taaataacag ttgtagcatt
     1801 tgtaagtgtc aagaatacag cacttacgtc atccattaca ccataaagca aagcaaataa
     1861 tgaaataacg attgattgtg ttagaacgac atttctagat acgccgtatt tgttttcttt
     1921 atggaatccg aattttggtg gaaggaatcc ttcacgagct acttggatga ttgtttttga
     1981 tggtccagta acccaagctg ataattgtaa aagcacacca ataaatacca tgaagctgaa
     2041 gatatttccg atcacttctg gtaagcctag gatttgacag tcaatcaaga taggctgcgt
     2101 gatatttgct aattccattt ttccatctgg tacgacattt gctacaagca tcgcattgat
     2161 gacattcaat aaaactaatc cgatcaaagc gataaatacg ccttttgtat aattttttgt
     2221 tgcgtctttc aaacgaggca tgtaaacaga actcatttcg atcccaacaa aaataaatgt
     2281 gataccagct aagtatttca atgaatcaat atgttccaag tcagggaaag cttttgacca
     2341 tgaaaagtca cctagatagc cgtttgagac tagtccgact ttgaaggctg ccaaaacacc
     2401 taaaacgaac atgatgacta ctgggatata tacccctagc catacaccga tgttcccgcc
     2461 gacttttgcc atatcgaatt tcaagttcaa gatcgtgatg atccagtaga taactaaaat
     2521 acaacctaaa acgaaccagt gattattgcc aagttctaca ttaccaaatg tgtttcctaa
     2581 caatggtcct aaagtagaag cgaccattac catacctggg aacatttgca cccataatag
     2641 ccatgcaacg acaaatcccc atttgctgcc cagtgctgtt tttacccata actgaggacc
     2701 gccttcttga ggaagcatcg tggaaagctc accggaaacc attgatatcg gaccggcaaa
     2761 aaacaaaact gcaaaaattg aataaaaaat caatgtccaa ccgactgcgg ctaacgtagg
     2821 aatactccga accgttgcac acagtgccat tgtcagaccg ataaaggtcc caagacccat
     2881 tttacttact tcagatttac tcaccgttga cactctcctt gattttttgg ataaaataac
     2941 ggtgtctttg aagtagtttc agcaataaac gaaacaattc agcgaatatt tgaggggatt
     3001 ctttgagttt attgcttgaa gggtttcttc aaagacaacc tcaaaacaaa gggatcgaag
     3061 agcttaggtc tccccttgct cttcagatcc aaacatgcgt cagaaacagt tagtattcaa
     3121 gctgttttct aacatgatta ccttgcttat tttgcgtcgc ttgccaataa ttggtctgcg
     3181 tagatttttt ccaatttttc ttgaagagct gctttgattt tttcagcata ttcttcaaag
     3241 tgttcttctt tgttcatgta tggtgtcatt acgctggcac gcaatacagt tacttttccg
     3301 gcacggttcc attcttcatc tgagaatcct agttggttca caaattgtaa tgggctgttg
     3361 ccatagtctg ggatagcaaa gtcagtatgt gaagttaaga actcattacc gtaaatgctt
     3421 cctttcacgt atgaagaata atcatatacg tcatggttca atttattcat tgcaactaag
     3481 tcatcgttgc ctttttcttt gaatacatag tctaccatat tgaaatctgg ataagttaat
     3541 ggatgaactt cgatttcttt gtctcctact ttaaatgaca agtcattcaa gaagttgtag
     3601 aaacgatgtg caccttcgat tgatgcaccc attaatttac catatcctgt gacattcaaa
     3661 ggtaagacat ggtgtgctgc ccaaacgctg gctgctgttg cccctgcttt tgaaccttcc
     3721 aagatataag ccccaagtaa tgctgggata tctgcgcctt tttcaaatac atatgtcgca
     3781 aagtaagaga taacgtctct catgcggata tctttgatga cgataccacc ggcagaatat
     3841 ggaacatagc ccattttatg tgggtcaatc gttacagatt ctgcttcttc gattgcttta
     3901 tacgcactgt gtacttcttc taagatataa tctttgtttt ctgtaaagac attgtatttg
     3961 taatgaacat cttttaaatc ttcaaatgga atgaagttgt tgtcttcgtc taagaaaatc
     4021 gcacggccgt atccgccata agcagcatct acgtgtaagt agaagtaaat accgtctttt
     4081 tctaatacgc gacgcaatgc aacgatttta tcgataccgt cgattgctcc ttcttctgtt
     4141 gatcctacaa caccgactac acctaggatt ggtgtttttt cagctgctag accacgaacg
     4201 attttttcaa gttcgttgat gtccatgcga tagttgtggt caactggcac tggaatcact
     4261 tggtctaaac cgataccgat gatgtcggca gcttttagcc atgaatagtg tttagtttgt
     4321 ggaaccaacc attttcctaa tttttctaaa tgttttccgc tacgtgctga gtgagctttg
     4381 atttcgtcga ttttttctgg gacgctgtct aacagattca tgatttcttc tgttgacaag
     4441 ttcattaatt cccaatcgct ttttccagca actagttcag gtgtcacttc tttcattgca
     4501 agcggcaatg atttgatgtt gcgggcatac caaagtcctt ctaagtttgc taaagaacca
     4561 tcagcaacga tgtggcccca gccatcttta tagctcatta attttgcaaa ttccattcct
     4621 acttcttctt ccatttggct tgttgcagga gaagattcat aggcaacgtt attaccattc
     4681 catagcatag caaaattgta cgctagtaaa gatggcatca atgtttcaga gttcatatga
     4741 ccccagtaac gtccggcatt atgccaagga acggaatggg tacgcatccg cgctgaaatt
     4801 tctgatagaa catcctttgt tttattcaca gtgtgttcaa aactagcact gcttttttct
     4861 tctggcgtaa taataggcat gtcttgaggc atgtagtttt gacgccagcc taaatgttca
     4921 tccaccaatt cattcaacaa agctttatag atttggccgt tctcagcttt gtccccaatg
     4981 aatagggcat ttaggtttag atctttcgac aatgattcac tcatagtgaa accctcctaa
     5041 aaaaatattt aaattttgtc gagccctaca ttacacctgt tcttctattc tgtaaactaa
     5101 gttttggcct gatttttaat catattttaa tatgtatcaa ttatccgaat tgttcatact
     5161 tttgaaataa ttaaaaaaaa cgagggaatt tacaaatgta aactccctcg caaagattgt
     5221 attaacgaca accagcgttc tattttagga tgggtttcaa aattggaatg ttgtaatagt
     5281 atttcccttt ttcaaggtaa aaacttacta aattctaatc aattactttg gccaaaaagt
     5341 aatttttctt accttttcga ataaccacaa acttaccatc gaattcatcg gatggattta
     5401 tgacaaaatt taaatcggta acgcggtcac cgttaatact tatagctccg tttgaaacat
     5461 cttcacgtgc ttgacgttta gatggttcaa tttttgtgga aacaagcagt tccacgatat
     5521 tttcaggtgt gcttgaaatt tcaacgttcg gcattttacc gaatccttgc gcgatttctt
     5581 ccgcatttag ttctttaata tttccagaga acaatgcttg cgttattttt tgcgcttctt
     5641 tcaagtcttc ttcactatgc acaaatcttg taacttcttc tgccaaacgg cgttgtgctt
     5701 cacgtttctc aggttctgtc tctacttttt tcgctaagtc ttcgatttct tcttgagaca
     5761 agaaagtaaa gaatttcaag tatttcacta catcgcgatc atcttgattc aaccagaatt
     5821 ggtagaactc aaatggtgaa gttttcttcg gatcaagcca aacggcaccg cctgcagttt
     5881 ttccgaattt cgttccgtca gccttcagca tcaatgggat cgttaaaccg aacgcttctg
     5941 cttctggtcc ttctaatttt cggattaggt ctaatccagc tgtgatattt ccccattggt
     6001 ctgctccacc gatttgcaat tgcacatcgt atgttttatg cagatgcaaa aagtcgatag
     6061 attgcaggat ttggtaagta aactctgtaa atgagattcc tacttccaaa cggctggcaa
     6121 cgatatcttt tgctaacatc gtgttgatgt tgaagttttt accgtagtct ctcaaaaatt
     6181 caagtaaaga gatttttgac aaccagtcgt agttgttcac aaatgtgata tttgcatctt
     6241 taccaaacaa ttttctcatt tgattggaaa gtgcgtccac gttatgttgc acttgttcca
     6301 tcgtttgcaa cacacgttct gttttgcggc cgcttgggtc gccgatcgtt cctgttccgc
     6361 cgccaatcag aatatatgga tgatggcctg ccaattggaa tcttttcatc atcataaatg
     6421 gaatcaaatg tccgatatgc atcgaatcac cagttggatc aacgccgcaa taaagtgaaa
     6481 tgctcttttc ttcaacgagc tcgcgaagtc tttcttcgtt tgtttgctga ttaatggcgt
     6541 cgcgccaagt taattcatca ataatattca ttttactgac ctccgtgtag tttttttatg
     6601 aaagcaggaa cctgctagca tgtgtaatta attatttctt caggatagga taggaaataa
     6661 aaaaagtccc ttggcatata agccaaggga cgaaatctcg cggtaccacc caatttgtat
     6721 gtctagatat ccaacatacc tctcgaacat ttaacgctgt cgcgtggcaa tcactgccaa
     6781 agactcctga aatgtaattc gctttaaagc atgtactggt ttgcagcgac caccagcttt
     6841 ctgaaacatt ggctttaaca actacttcgt ttcgatcttc gtcttgttat tattaatatg
     6901 tgtctatcat agagcgcaac tttttctttg tcaacagaaa aaggatattt tttttaaatt
     6961 cctcattttt tcttttttga atccgctcta attccgaaca ttttattttc aattattgtt
     7021 aaaagaaata actttttctg tattttttct gcaatttatc gagaagtcac tttactttgc
     7081 ctcttattct ttcttcgtta caataaggaa tgggacaagt aaaaaaatga aaaagcaagg
     7141 gacgaggtat atggaaaaaa agcaaaaaat tattttagga gccacttctg ctttaactat
     7201 cgttatttta attctaagtt tgttttttgt catccgatca tctacaaaaa aagaaccaat
     7261 cattcctgaa aaaaaaataa cagaaaaagc aaaagaaccg acagatgata agcaacaact
     7321 agttactcaa gcaaaaaatc tggctcaaag ctacgattat gaccaagcga ttgcgttatt
     7381 ggaaaaagat agtaagaacg gatctactga aacacaacag cttcttcaaa cactaaaaaa
     7441 ggagaaagaa caactgatcg actggtctga tcctactcag atctctcatg tctttttcca
     7501 cagcttgatc gtggacccgc aaaaagcctt ccactctcaa caggcacaag gatacaaaga
     7561 ttatatggtg actgttgaag aattcaaccg ttcgatcgaa caactttatc aaaatgattt
     7621 tgttttagtt aatttgaatg atttgatcca aaaagacgaa caaggaaatc tttcctttaa
     7681 cgggcttgcg ctacctgaag gaaaaaaacc attggttctt tcacaagatg atgtcagcta
     7741 ttatgaatat atggataatt ccggttttcc tagccgattg gtcgtatcaa ataacaatga
     7801 aatcaaaaat gtctataaag agaaagataa agaagaaatc ggtgactttg acatggttcc
     7861 tctgatcgat gcctttgtca agaaacatcc tgatttttct tatcgaggcg caaaaggtac
     7921 cttggccctg acaggttaca acggagtttt aggttatcga acatcaaaat ctcaatatgg
     7981 agacaatgaa aaaacaaaaa aagagattaa agaagctaaa aaagtggcgg aacagttgaa
     8041 gaaagacggc tggagctttg cttcccatac atggggtcac ttgaatatga ctcaagcttc
     8101 actagaagat gtaaaaaaag acaatgaatt gtggcagcaa gaagttgcac ctatcctagg
     8161 aaaaacaaat attctgattt atccatttgg tgcagacatc agcgactggc agccttattc
     8221 agcagaaaat caaaaatttg cttacttgaa gagtcaaggt ttcgatattt tctgtaatgt
     8281 cgatgcttct acaccagctt ggggacaatt aggtacggat ttctatcgaa atgctcggat
     8341 caatatcgat ggcattcgtt ttcaatctga tttagacgga aaaaatccta ttcttgatcc
     8401 attcatcaat gtccatgatg tctatgacaa agaagcacgc gaatctgctt gattttacgt
     8461 catttatgaa ccaaaaaagc cgaactgaca ttttatcgtc agtttcggct tttttatgct
     8521 ttatttcttc ttcggtgcga ttcccttgat caggacttct gtccattctg ctgtatatgg
     8581 aagcagtttt gcgtatatct ccggcttaga aattccttct accattgctt gaaaatagag
     8641 gatcaagaac tcatccgaat atttcaaatc cacttttcct tctttccgcc ctcgatggaa
     8701 aagatcaagc atgatactga aactttcttg cgtatacgca tccatcgcgt cagaaaattc
     8761 ttttttttct ttttttgtat agtatgtcat caaatcgata taaaattgtt tgttcactcg
     8821 attgagataa cggattttgt tttcactcat ggcaatcagt gtttcttcaa atggaagatt
     8881 ttccgcaatc aacgctttcg cttcttgccc taaatcattc ataaatgcaa aaaatacttc
     8941 ataaatcagc ccttccttgc tgccaaaata tttaaaaatc gtcgctttac ttacctgagc
     9001 gttctcagct accttatcca ttgtcactcc agcggttcct atgtctgtgt tcatcaagtc
     9061 aaaagctgct tgtaaaatct ctttcttttt ctcttgtgct ctcttttcaa aaccgttcat
     9121 ttgtagagcc tcccgtaatt ttaaactttt ataatatata tagttcaaat ttattctgag
     9181 gtttattata actatctatt gagaaagtat caagctagct attccttgtt tatgaattca
     9241 ttgacagaaa tttataaaaa gaatattatg tactaaaata ataaaaaaag ttttataaaa
     9301 aggtataaaa cctttttatt aaactattta atcttgttta gtatatattt ttagaaaaag
     9361 gagtggggtt tttatggcag aaatcgtcaa agtcacacat ttgaaaaaga gctttggtcg
     9421 tttcgaagct ttaaaagatg tctctttcac cgtacattca ggtgaagtcg ttggatttat
     9481 cggaccaaat ggttctggaa aatccacgac gattcggaca cttttaggga ttataaaaaa
     9541 agacggcgga acggcaacga tttttgggca agatgtatgg gaagatagtt tatctatcca
     9601 tgaacgtctt tcttatgttc caggcgatat ctctttgtgg ggaaatttga ctggaggagc
     9661 gatcatcgat ctcttcatga agcttcatgg aaaagggagt gctcaaaaaa aagatgaact
     9721 gattcaacgt ttctctcttg atcctaagaa aaaagcaaaa aactattcaa aaggaaatcg
     9781 ccaaaaagtg ggcttgattg ctgctttggc tgttgattcg gatctctatt tatttgatga
     9841 gcctacttct ggtttagatc ctttgatgga aacgattttc caagaagaag ttgaaaaatt
     9901 gaaagaacag ggcaaatcca tcctactttc ttctcatatt ctcagtgaag tcgagcgact
     9961 agcggataaa gtcgtgatca tacgcgaagg aacactcgat gaagaaggaa cactcgatga
    10021 attgcgtcat ttgactcgtt cgaccatcac tatagaaaca gaagcagaga atagtcactt
    10081 agcacaattg aacggtgtcc atgactttgt gcaaaaaggt cacctcgctc aatttgctgc
    10141 tgataacgaa gctttcgatg tgattttagc tgaagcgtcc aaattaggtg tgaaaaaatt
    10201 tgaatctatt ccaccgactc ttgaggattt attcatgaga cattatgaag gatgaggagg
    10261 aagcgaaatg actgataaat tttcacgctg gtccaccctt ttttctcaaa accttagccg
    10321 tgactggaaa aagatcctga tatggctagt cggtgtcact gctttttctg gtggttttgt
    10381 ccctgcgttt gaagaattga cttccggaca aggattagct ggattatacg aaaccttgca
    10441 aaacccggca atgattgcaa tggtcggacc aactccagct tcgaatgctg ctgagtatac
    10501 tttaggagcg atgtatgcaa atgaaatgtt gcttttttgc agtttgtttg ctgctgtgat
    10561 ctctgtttta cacgtggtga gccaaacgag aaaaaaagaa gaacttggtc tgattgaact
    10621 tattcgttcc tttcgagtcg gacgtcaagc aaactcttta gctgtcatcg ctgaaagtat
    10681 tctgatcaat ttgcttttag caatatcgat cagctgtacg atgatttttt tccaagcgga
    10741 ttcgatcact gcagaaggtg cttggctttt tgggctatct gtaggtagta tggggatttt
    10801 ggggagtgcc gttgcactgt ttgctgcaca actgatgcca agttcagcca gttcgaatgg
    10861 tctgtcttta gcgtttttag gtggacttta ccttctacga gcaataacag atgtagctga
    10921 ttcctccctt tcgatgtgga atcctttagg ctggtcttat ttgacctatc catttacaac
    10981 taacaactgg attcctttgc tttatttgtt tttgttcagt ctaatcttga taatcagttc
    11041 atttgtttta gaggaacatc gagatttgaa caccggctat atccccgaac gtgaaggaaa
    11101 accgtatgct aaacgttctc ttttatcctt gcgtggttta ttattctatc taaataaagg
    11161 gatgacaatc agttggctta tcacttttgg tttgatgggg gcggcatacg gctctatcta
    11221 cgggaatatg caacagtttt tagaaagtaa cgacttaatg aaacagatgt ttatccaatc
    11281 tggcgtctca attgaaaaaa actttacaag cacgatcatg gtcgtcttga tttgtctagc
    11341 tgctatttta ccaattgcta gcatcaatcg tttatttaca gaagaaaccc acggacgtat
    11401 gaatcagctg ttcgcaacaa aaatttctag gaaccaactt tattggacca atatgttact
    11461 agctattcta tttgctatat tggcaatcct gattagttct ggtgcactag ggctttctgc
    11521 tttggcttcg atgaaggatg cgaaagacat ggatctattg atgtttctta aagccgggtt
    11581 caatttcctg cctgccgttt tagtgtttat cggaattagt ggctttctat tcggatggct
    11641 tcctcgaatc ggtaaacttg cttatatcta cttagcttac tcctttgcac tcaattactt
    11701 tggcggaatt ttggatttac cagaatggtt ttccaaaaca gctgtcccta gctgggttcc
    11761 acggatgcca aacgattctt ttgatctttc cgtgttcctt acgttatcat gtatcagcct
    11821 tgcactgttc gtccttggtt ctattggtta taggcgaaga gacttactag aaggataata
    11881 aaaaagcatg tacaatttca tgctagcctc caaatctggg tcaaaaatcc aacatttgga
    11941 ggtcattttt ttatttacaa gtcttctaac tgctctttat caatgatcca gacttctcga
    12001 ttctttcttt ttacataacc attctcctct aataatttaa attttctaga taaagtttcg
    12061 ggggtcgtac cgataaatgc agcaagttct ttcattttca ttggcaggaa aaagtgatcc
    12121 ttccctgtcg ctttagctaa gtcaagcaga tagacagcga ctcgttcttc tactttttcc
    12181 atcatcaaaa aagttgtctg ctgctgtact tttgttaatt tctcaacgtt gattgctaaa
    12241 agtttcagac taagggcggg ataatgcagt aagagttccg agaaatcttt ttgtctcaat
    12301 atgcaaattt ccgttttttc tagtgcttcg ccaaataaag actcatttgg aacgcctagc
    12361 aactggctct ctccctcata tccgcccggc tctattactc gtaaaagctg ttcctttccg
    12421 ctagcagata attgatacac tttcatactg ccggaggcca cgatcactaa ttgaggttct
    12481 ccattcggcg caagaatctg ttctcctttt tccacatagt gatgtttgac aagtgcgtgt
    12541 actttttctt gatcttgctg tactaagtga ttgaacaaag gaacaaatga aacacataaa
    12601 tgatcatgac tcataatctc tcctccttct aaacagctat ttctaataaa gaaacataac
    12661 ttcccttatt ccaactgata attttctttt atcatagcat aaacgtcaag cgaaccagat
    12721 accagcaaat agagtggatt tctttttgtc ccttgcttta ttttccttct tttgagacct
    12781 taagtaattg attcctatca attttttaaa tatttacttt ttgaataatc aaaaacaaac
    12841 cttcactcgc aagccgagag taaggtttgt ttttcgcatt gcttatttcg tgttgtctat
    12901 tgaaattttt ccgcacctag cttttgatat agtggtgcta gttcttgtaa ggtttcagcg
    12961 gttatttgct caacgtgttc gatttcttgc ggatagaaga atagtttacc catttgaaag
    13021 gttcggtctc tcatcgcttt tttcaactct tcttgtttct ttgtatcgga caaatagtca
    13081 gacaaagcta agtggtcgtc aagttcatgt tctggttgcg gccatatgta ataatccttg
    13141 atatcgactg ttttgctcca ctctttcagt atcgcaagca actggttata cgctgcaatg
    13201 ctaccatatc gttcttcgct tttataatgt tggtacatca aatagatttg gtattgtttt
    13261 tgattcaaca aaactgctag acaggcattc tcgtcttgac gagattcgct tcggtacgcg
    13321 ctccaaaaat gactgcgtaa attccagcca ttcgtccagc tttcgatttt aggtttgctc
    13381 atgccgtaca tatcaggcaa aagtgcagct gtctggagct gaatctcttt ccatttttgc
    13441 cagtgttctt tatattcttt cttgatttgt tcaatcttat ctgttggatg gctctctttg
    13501 agctgtttga atgcgtagat tggtcgatca aacaactgat aatctgattt tccaagttcc
    13561 attgtttcgc ctctttccgt tatcttttgt attctacctg aattttgcga tatggacaaa
    13621 tagaggttgt gaaaaagctg ttctgcatca agtcataaga acagccaaac aaaaaactgc
    13681 gatgagcatc accgcagttt tattgaactt aaggttgatt gatcacatct aaaagcgttg
    13741 aaaataaaat ggcactagaa gcagctcctg ggtcgatatg tccgattgca cgctctccta
    13801 gataggaagc tcgtcctttt ttagctacca agactttggt gtgttctttt gcctggtcaa
    13861 tgatttcttt tgttaaattc cctgccttca atgcctctgt gactggcagc caaacatcta
    13921 acatcgtttt atcgtcagct tctgcctttc ctcggctttg aatacccgct gttccctgct
    13981 cgatcacttc gcctaatttt tcttgagaat caatagaatc gacctctttt gtcgctttca
    14041 tcatgttcat gaatgcagat ccgtataacg gaccagaagc cccaccgact ttcgatatca
    14101 tcgccataga gaatactttg aatgtatcgc tgattgtttc aggatgatcg gcttgaaaag
    14161 cttcttcata agctgaaacc cctcttccca tgttatttcc atggtctcca tcgccaatcg
    14221 gggtatctag atcactgaga tattgtttgt tctgattgat tgcctctgca aattgcgtga
    14281 gccattcttg gatttcttga acggttagtt tcatattatc acccttttat cttgagattt
    14341 tttaccatga aatcgtctgt acattgcttt ctaaagaatc tttccattgt gtctccgtca
    14401 agtcgatcag tgttagagaa agaccttgca tatctagtga ggtcataaaa ttaccgactt
    14461 ttcggaaaac tacattgacg cctctttctt ccaacagagc taaaacatca ttcatgaaca
    14521 cgaactgttc catcaaaggc gtcccgccca ttccgttgac tagtacacct gcttcttttg
    14581 gtaaattcga gtaatcatct aaaatcttag taacaagttc ctttgccagt actttagaag
    14641 gctgcatctt ttctcgacga tagcctggct caccgtggat accaacacca tactcgatct
    14701 catcttctcc tagttcgaat cctggtttcc ctacttctgg tacagttgct gctcgaagcg
    14761 ctagaccgat cgtcttagtt gcctgtacga ccttttctcc cagttctttc aactcagcta
    14821 gggaagcacc gtttcttgct gcatcgccca cgattttgtg tacaaggaca gtacctgcaa
    14881 ctccgcgttt tccagcagta tacgtactat tttcaacggc gatatcatca tctacgatca
    14941 cactttctac ttcaatatcg tccatagcag ctaattcctt tgccatatcg aagttcaatg
    15001 catcccctgt ataattctta acgatcagca aaactccttt tccactatcg gcttccttaa
    15061 tagccgtctg aatctgatct ggagttggag aagtaaacac atcaccaagc accgctgcac
    15121 ttaacatccc ttcccctaca aacccggcat gggatggttc atgtccgctt cctccaccag
    15181 aaaccaaacc aacttgttcc gctttctgat tcttggctac aacacgggaa gattctacac
    15241 gatgaacaag ttctggatag ctttttacta atccttccag catttcttcg acaatattgc
    15301 ttggatcatt catgattttt ttcaatttat tcccatcctt tctttccggc attttgtgct
    15361 tctgttaaga tttgctgagt atcatctgtt ataccggcag tgatggctgc tgcaaaagct
    15421 ccttccacta aaggcgcatc caccagatga taacgttgct gctgctcttc ttccaacatg
    15481 tcttttgcca gttccgagtt caataccgcg ctaccgatat ccgcaaaaac aaaataacta
    15541 gctgcatcgc ttgattcatt gactgcttct acgattttca tcgggtctga tccgatctcg
    15601 ccatttattc cgccgagaga aaaaatttgc acctcttcgg atttttgcat ctgctcaatc
    15661 atttctttaa taccatctgt tactttttga ctatgagaaa taagcaaaat actttttttc
    15721 acaagaatct tcctttcttt tacatagttg ctaacgattg gtttcgcttt cattaatgaa
    15781 caattcaagt atataataaa t
//
LOCUS       DASHXG010000057        14738 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.058, whole genome shotgun sequence.
ACCESSION   DASHXG010000057 DASHXG010000000
VERSION     DASHXG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.058"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            4..2376
                     /locus_tag="U2R59_002213"
     CDS             4..2376
                     /locus_tag="U2R59_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966565.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKVAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="U2R59_002214"
     CDS             2437..3897
                     /locus_tag="U2R59_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEM8966566.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="U2R59_002215"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="U2R59_002215"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEM8966567.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="U2R59_002216"
     CDS             6128..6277
                     /locus_tag="U2R59_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966568.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="U2R59_002217"
     CDS             6352..6945
                     /locus_tag="U2R59_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEM8966569.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="U2R59_002218"
     CDS             6958..7857
                     /locus_tag="U2R59_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEM8966570.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="U2R59_002219"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="U2R59_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8966571.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="U2R59_002220"
     CDS             8723..8983
                     /locus_tag="U2R59_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966572.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="U2R59_002221"
     CDS             9428..9634
                     /locus_tag="U2R59_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HEM8966573.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9682..9885
                     /locus_tag="U2R59_002222"
     CDS             9682..9885
                     /locus_tag="U2R59_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966574.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="U2R59_002223"
     CDS             9901..10338
                     /locus_tag="U2R59_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966575.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="U2R59_002224"
     CDS             10331..11038
                     /locus_tag="U2R59_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966576.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="U2R59_002225"
     CDS             11418..11597
                     /locus_tag="U2R59_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966577.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="U2R59_002226"
     CDS             11922..12185
                     /locus_tag="U2R59_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HEM8966578.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="U2R59_002227"
     CDS             12179..12529
                     /locus_tag="U2R59_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8966579.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="U2R59_002228"
     CDS             complement(12553..13167)
                     /locus_tag="U2R59_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966580.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIITSVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13481..13903
                     /locus_tag="U2R59_002229"
     CDS             13481..13903
                     /locus_tag="U2R59_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966581.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13913..14116
                     /locus_tag="U2R59_002230"
     CDS             13913..14116
                     /locus_tag="U2R59_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966582.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14318..>14738
                     /locus_tag="U2R59_002231"
     CDS             14318..>14738
                     /locus_tag="U2R59_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966583.1"
                     /translation="MIFLKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSN
                     RPGLEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKS
                     SSTGQLMFHLFAAFAEFERNLILERSAAGRAAARARGR"
BASE COUNT         5435 a         2399 c         2982 g         3922 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaatgaa caaatcgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gttataacaa gtacggcgga
      301 ctagatatga cgatcgaaaa tattccaaga atcagagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgt ctttttcagc cgccacgatc cgaaaatatc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt aacgcaatgg aaaaaaaatc cgaccattta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactgaat gaaaacgggg aatttgagga atctaaaaaa
      601 taccaagcca catcggaaga ggaaaaagta gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctctgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggagaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga caaccaatac gctgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgagaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggttacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcaatcgca acaccatttt taagatcttc
    12661 aacgatgctt ttgtaaacaa ggcgacgttg gggatctttt gcgtctgcac tgtataattt
    12721 gggccgccct ttgtagacgc cgtttgcttt tgcgatctta attccttgtg cctggcgacg
    12781 tttcgattca gtccgttctt gttcagcgat catggccaaa atttggatga tcagatcctt
    12841 aatgaattta tccaggagag gattgccaat tgcttcagcc atgatcggta aactagtaat
    12901 gatcagcttc acatttttct tcttcaagta attgactgaa gtgatgatct cgtcataatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgtaatctaa
    13021 tgcttcttgg aaaacaggtc gatgagtaat cgttgcgcca gattgtttct cgatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctggcgt tgttcatttt gatcgatcga
    13141 tgagacacgt atgtatgcaa ctctcaaaac ttttacctac tttctgcaac tatttaaaat
    13201 acaccctaat catacacgag gaagccatat ttttcaatgt tataccagtg tctatttagg
    13261 gtaaacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
    13501 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
    13561 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
    13621 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
    13681 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
    13741 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
    13801 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
    13861 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
    13921 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
    13981 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
    14041 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
    14101 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
    14161 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
    14221 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
    14281 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
    14341 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
    14401 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
    14461 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
    14521 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
    14581 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
    14641 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
    14701 cgcagcagga cgagcagctg ctcgtgcaag aggacggt
//
LOCUS       DASHXG010000058        14564 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.059, whole genome shotgun sequence.
ACCESSION   DASHXG010000058 DASHXG010000000
VERSION     DASHXG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.059"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..614
                     /locus_tag="U2R59_002232"
     CDS             <1..614
                     /locus_tag="U2R59_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEM8966584.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="U2R59_002233"
     CDS             611..1384
                     /locus_tag="U2R59_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HEM8966585.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="U2R59_002234"
     CDS             1381..1779
                     /locus_tag="U2R59_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HEM8966586.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="U2R59_002235"
     CDS             1964..2635
                     /locus_tag="U2R59_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966587.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="U2R59_002236"
     CDS             2694..3134
                     /locus_tag="U2R59_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966588.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="U2R59_002237"
     CDS             3146..3814
                     /locus_tag="U2R59_002237"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HEM8966589.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="U2R59_002238"
     CDS             3878..4501
                     /locus_tag="U2R59_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEM8966590.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="U2R59_002239"
     CDS             4557..4943
                     /locus_tag="U2R59_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEM8966591.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="U2R59_002240"
     CDS             5156..6547
                     /locus_tag="U2R59_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HEM8966592.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7158..7526
                     /locus_tag="U2R59_002241"
     CDS             7158..7526
                     /locus_tag="U2R59_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HEM8966593.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7706..8647
                     /locus_tag="U2R59_002242"
     CDS             7706..8647
                     /locus_tag="U2R59_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEM8966594.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8716..9447
                     /locus_tag="U2R59_002243"
     CDS             8716..9447
                     /locus_tag="U2R59_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEM8966595.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9591..11771
                     /locus_tag="U2R59_002244"
     CDS             9591..11771
                     /locus_tag="U2R59_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEM8966596.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11791..12273
                     /locus_tag="U2R59_002245"
     CDS             11791..12273
                     /locus_tag="U2R59_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEM8966597.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12289..13050
                     /locus_tag="U2R59_002246"
     CDS             12289..13050
                     /locus_tag="U2R59_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEM8966598.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13181..14515
                     /locus_tag="U2R59_002247"
     CDS             13181..14515
                     /locus_tag="U2R59_002247"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEM8966599.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
BASE COUNT         4772 a         2450 c         3214 g         4128 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     7141 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     7201 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     7261 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     7321 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     7381 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     7441 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     7501 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     7561 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     7621 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     7681 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     7741 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     7801 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     7861 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     7921 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     7981 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     8041 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     8101 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     8161 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     8221 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     8281 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     8341 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     8401 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     8461 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     8521 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     8581 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     8641 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     8701 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     8761 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     8821 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     8881 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     8941 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     9001 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     9061 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     9121 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     9181 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     9241 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     9301 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     9361 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     9421 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     9481 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     9541 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     9601 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     9661 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     9721 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     9781 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     9841 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     9901 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     9961 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
    10021 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
    10081 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
    10141 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
    10201 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
    10261 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
    10321 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
    10381 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
    10441 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
    10501 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
    10561 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
    10621 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
    10681 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
    10741 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
    10801 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
    10861 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
    10921 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
    10981 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
    11041 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
    11101 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
    11161 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
    11221 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
    11281 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
    11341 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
    11401 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
    11461 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
    11521 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
    11581 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
    11641 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
    11701 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
    11761 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
    11821 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
    11881 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
    11941 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    12001 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    12061 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    12121 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    12181 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    12241 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    12301 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    12361 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    12421 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    12481 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    12541 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    12601 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    12661 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    12721 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    12781 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    12841 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    12901 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    12961 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    13021 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    13081 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    13141 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    13201 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    13261 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    13321 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    13381 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    13441 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    13501 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    13561 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    13621 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    13681 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    13741 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    13801 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    13861 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    13921 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    13981 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    14041 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    14101 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    14161 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    14221 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    14281 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    14341 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    14401 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    14461 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    14521 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaa
//
LOCUS       DASHXG010000059        14114 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.060, whole genome shotgun sequence.
ACCESSION   DASHXG010000059 DASHXG010000000
VERSION     DASHXG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.060"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..555)
                     /locus_tag="U2R59_002248"
     CDS             complement(<1..555)
                     /locus_tag="U2R59_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HEM8966600.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(571..1050)
                     /locus_tag="U2R59_002249"
     CDS             complement(571..1050)
                     /locus_tag="U2R59_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HEM8966601.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1056..2080)
                     /locus_tag="U2R59_002250"
                     /pseudo
     CDS             complement(1056..2080)
                     /locus_tag="U2R59_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2097..3203)
                     /locus_tag="U2R59_002251"
     CDS             complement(2097..3203)
                     /locus_tag="U2R59_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HEM8966602.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3432..6029)
                     /gene="adhE"
                     /locus_tag="U2R59_002252"
                     /gene_synonym="adhC"
     CDS             complement(3432..6029)
                     /gene="adhE"
                     /locus_tag="U2R59_002252"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEM8966603.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6334..6714)
                     /gene="yajC"
                     /locus_tag="U2R59_002253"
     CDS             complement(6334..6714)
                     /gene="yajC"
                     /locus_tag="U2R59_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEM8966604.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6811..7956)
                     /gene="tgt"
                     /locus_tag="U2R59_002254"
     CDS             complement(6811..7956)
                     /gene="tgt"
                     /locus_tag="U2R59_002254"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEM8966605.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8174..8872
                     /locus_tag="U2R59_002255"
     CDS             8174..8872
                     /locus_tag="U2R59_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEM8966606.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9040..11679)
                     /locus_tag="U2R59_002256"
     CDS             complement(9040..11679)
                     /locus_tag="U2R59_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEM8966607.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12298..13329)
                     /gene="queA"
                     /locus_tag="U2R59_002257"
     CDS             complement(12298..13329)
                     /gene="queA"
                     /locus_tag="U2R59_002257"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEM8966608.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13522..>14114
                     /locus_tag="U2R59_002258"
     CDS             13522..>14114
                     /locus_tag="U2R59_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8966609.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMD"
BASE COUNT         3957 a         3095 c         2542 g         4520 t
ORIGIN      
        1 agcgcctacg agataacctc ccataaacaa agcagagatc gaagcaccac cagcaacaag
       61 tgaatacatg ataaaagcag tacttggagg aatgaccata cctgtcggag ctgacgcgat
      121 attgaccgct gtcgcaaact tccggtcata tccttcttcc acttgctgag ggatcaacac
      181 tccaccaatc gcggtagaag cggcaatggc cgagctagag atggaaccaa ataaagcatt
      241 ccctaacaca ttcgtatgag ccaaagcccc cggcacgcgc ccgacgaaca acatcgcaaa
      301 atccactagt ttcttagcta tccctccatt attcatgata atgcccgaga gaacgaaaaa
      361 cggaatagcg atcagcgaaa aactattgat acttcccacc attttttgag ctgaactaaa
      421 agcagaaaca tcaaacggta taactaacaa taaagtcatc atcgatgaga atgcaatact
      481 tatagcaatc ggcatcccta atacaagcaa cacaacaaat acaaaaaata acactaatcc
      541 ggcttctatt gccattttat tcctccattt ttatattttt tcttgaattg ctggcttgtt
      601 gcttaatgta tcgattagat tgatcaggct atagataatg atgagtaccc ccgatacagg
      661 tactgacaga taaacatatc ccataggaat acttaaagaa ggcgagatct gccccattgt
      721 caatgtgaca gcattccatc cgccatacac catgatcatc gcagcaaata ccagaaataa
      781 actttgaaca acaacttcta aaattttact ttttttgcca gttaattttt cacttaaaac
      841 cgttacggct aaacgtgctt tttgtcccac aacatacgcg gaagacaaca tggcaaacca
      901 gacaagaccg aatcgaacaa gctcttccgt gaccgtattt ggatttccta aaaccgttct
      961 ggaaaatact tgccataaaa caacagcgac catcccaaca agcaaaacag ctcccaggat
     1021 ctctaatacc ttgtttaaaa tcattttcat tacagctacg ctccttgctc ttggatcttt
     1081 tgataaaggt ctttgtaggt aggatcgttt ttgaatatat catgaagtgg ggcaactgcc
     1141 tctcgaaacg gtgtattatc tacatcattg aattggactc catgttcttc ttgtgctaaa
     1201 gctttttctt cttcaattgc ttttgcaaaa gcttcaattt caaaaaccgt tgattctttc
     1261 gctgcttctt caatggcttt ttcctgttca tcagttagct gttctttgat ggcatcattc
     1321 atgatgatga tatctggcac acgtgtatgc tcatcatagg aatagtattt agctaccccg
     1381 ccatgtccag ctgtatacaa gacaaattca ttgttttctg atccgttgat caaattggat
     1441 tgaagagacg tgtacacttc atcacttccc ataggtacgg gcgaaccgcc taaaagctct
     1501 accattttga tagcggtttc gctttgcatc acacggatct tctttccctt caaatcttcc
     1561 ggcgtatgga tcggaccgtc taccatataa aagctgcgct gaccagaatc ataataggtc
     1621 aatccggtaa atcctaaatt tttggtcgat tggtagattg gctccattat ttcttcatta
     1681 tccatcacct taaagaaatg ttcttcatca ttgaatagat aaggaacgga aaaaatcgaa
     1741 taatctttag agaaactttc caacgctgag gcacttactt ttgtgaaatc tactgctcct
     1801 gactgtgtca attcgatcag ttcacgttct ccacccagtt gtccatctgg gaaatactgg
     1861 atctgtacgg aaccatctgt tttttctttt actaaacgcc caaattcatt cattgcatca
     1921 attactggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt acgtctgcat
     1981 ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc agacctaggc
     2041 taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc tttcttttaa
     2101 caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc ataaggcatt
     2161 gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt cccgattgaa
     2221 acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat agcacgataa
     2281 gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa aataccgtaa
     2341 gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa caacgtatgc
     2401 cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc aagtgtttcg
     2461 atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat gatctctgga
     2521 atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata gttatgattt
     2581 ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa gtatttgata
     2641 tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa cagtttcccg
     2701 atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg attcttattt
     2761 tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat gtcattcatg
     2821 acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt gtcttcatac
     2881 aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg agcgccttct
     2941 tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt ttttgtcatc
     3001 tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca cactgtccag
     3061 cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt atcgtctttg
     3121 atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc tttaggtaca
     3181 aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc attttatatc
     3241 cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa aactgtctaa
     3301 aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat taaaaaaaga
     3361 acttggagaa acaacgtttt ccaagttctt tttcatctat tttcttatct tttttctacg
     3421 ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc agagatcaat
     3481 ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc catacggtct
     3541 acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat gttgatgccg
     3601 acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc ctctgttgtt
     3661 tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc acggaaatag
     3721 tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg gataatatgc
     3781 ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc gattttatgt
     3841 gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc cattgtagaa
     3901 gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt ttctaaatag
     3961 tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga agccatgact
     4021 gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc tgtgacagat
     4081 gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt caatgcataa
     4141 tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa tggcgttact
     4201 tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc tggtttgtcg
     4261 atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa gaaagatgtg
     4321 tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga accgcctcca
     4381 agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc gtatacggta
     4441 tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc atttttacgt
     4501 cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc agggtcacaa
     4561 acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga gttcttttca
     4621 aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt cgctacagtt
     4681 ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt accataagaa
     4741 ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat gccgccttct
     4801 gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa tttgacatgc
     4861 aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag attcaacata
     4921 ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc aagaactgga
     4981 gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc agcaatcagc
     5041 attttcgttc cttttggtac actgattcct gccaattttg cgatttccat cgcagaatgt
     5101 ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc ttctaatttt
     5161 tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc ttttactgct
     5221 gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat tccattatca
     5281 aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt tttttcaata
     5341 taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga gtaagcagac
     5401 ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg gttcattagc
     5461 atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc aggagctccg
     5521 gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt ttgggcactt
     5581 ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga tttgaaaatc
     5641 gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac tggttcagca
     5701 atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt atcatgtttg
     5761 atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc ttcgtaaaca
     5821 ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc caaagctgcc
     5881 attgccattt catgcacgat atggtctact ttttcttgat caaagctttc catttctttc
     5941 aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc aattgtcttc
     6001 gttttttctt tttctattac tttagccatc attatcctcc taatgggtca tggttatttg
     6061 ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca cttttttgtg
     6121 atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt ttgtatagaa
     6181 aaatatataa agttatttat tattatttat atgacacacc cgattattca atattgagca
     6241 atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag gacatctttc
     6301 tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct cttctgtctc
     6361 ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt cttctgttgt
     6421 ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg ttttgattgc
     6481 tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc gtttgtcatt
     6541 gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat cacctggttt
     6601 catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac gtgacataaa
     6661 aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc ccattttttt
     6721 cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg ataacactag
     6781 ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt ctttattgaa
     6841 cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca tgattgcttg
     6901 acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag tcaaacgaat
     6961 cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat agtttttaca
     7021 tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt tcgcattttt
     7081 cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc gagtaggcaa
     7141 gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat cagcagcacc
     7201 gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga attctaatac
     7261 acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt aaccagggaa
     7321 atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc ctgctccttg
     7381 gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc ctcgttctgc
     7441 ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat cgaatggtgg
     7501 acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt tgattgcttt
     7561 ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca cgccttcttc
     7621 ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat ctgttaaaat
     7681 cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta agtcttcacc
     7741 agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca tttctttcaa
     7801 ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga acattggtgt
     7861 ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat gtttttcttt
     7921 cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt tctatataaa
     7981 atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag ttccctcggc
     8041 ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata acaaaaaaaa
     8101 gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta ttaaagaaaa
     8161 ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag agagtctaaa
     8221 aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg gtattgctac
     8281 tattcttctt attatgattc ctattatctt gtttgccacc accatatatg atggatcagc
     8341 gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg gcggaattat
     8401 ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc ttgatatttt
     8461 acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat tcaaaggttt
     8521 gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa cattatgggg
     8581 tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa gctattttat
     8641 ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata cgatcactgc
     8701 aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc tttcatttat
     8761 cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc tcagcccata
     8821 catttctgca acaaaagcag cattttatga acaattgcca aaagatattt aaaagagagt
     8881 gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca gtaaaagaaa
     8941 cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct cctttttgta
     9001 tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt cttctgcttc
     9061 cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag ataaaatccc
     9121 taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt gcgtaaatgg
     9181 cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta ccaaagcttt
     9241 attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga acacatgcag
     9301 aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct gacttgcgtc
     9361 tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca aggttacgat
     9421 ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa agatcccttc
     9481 atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc ttcctaaagc
     9541 aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag ctgtaaatgg
     9601 tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa tattacagct
     9661 tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt gactgacagc
     9721 gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac tttgcgccac
     9781 atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg ctggtgcatc
     9841 attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag atttgacgat
     9901 ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga cacgcgcatc
     9961 taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg acggatcatt
    10021 caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc cagtgatcat
    10081 gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt ctggacgtgg
    10141 tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg cttcagaaga
    10201 aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc tcagtgcccg
    10261 tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac taaagcgcgg
    10321 agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca tttggtgaac
    10381 tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg gatatttttc
    10441 ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg ctacttctgt
    10501 tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat ctgtacatag
    10561 tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga tattcgttac
    10621 ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca gcgttcctgt
    10681 tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca actgtcggat
    10741 gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg taacaataac
    10801 agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga acatctcaag
    10861 gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg ctaaagcgat
    10921 catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt tttgcatagt
    10981 attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa tggcagtgac
    11041 gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat taagttggtc
    11101 acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg cttcactttc
    11161 tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac gggcatcggc
    11221 agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt gctctgactc
    11281 aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca tatcttgcaa
    11341 ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg agttgatcac
    11401 aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag caaatgcggt
    11461 ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg acaagcttcg
    11521 aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca atccctgctt
    11581 ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg cttctgttac
    11641 cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc tttaaaatct
    11701 tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac ttcaaataaa
    11761 gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat ttgcaaacgc
    11821 taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat agacagaaga
    11881 atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt tcacccagac
    11941 atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg atcacgaagt
    12001 atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt ctgaaaattg
    12061 aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat ttttgtttaa
    12121 catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat catttctgtt
    12181 tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg ctttttcttt
    12241 gtcataaaat ctttgtaaag cttttttgtt attcaaaact agcggctttt cataacctta
    12301 tttcacgaac atcgcatctc caaaactaaa gaaacgatag cgctcttcaa tcgcatgctg
    12361 gtaagcagat aaagtcaatt ctcttcctgc aaaggcacta actaacatga ctaaagtcga
    12421 ttttggcaaa tggaaattag ttgagaaagc ttctaccact ttgaattcat agccaggcgt
    12481 aatgaaaata tcagtccatc cgctgtctgc tttgatttct ccattaaatt tcgttccaat
    12541 cgtttctaat gttcgaattg aagttgttcc gacagccacg attttcccgc catttttacg
    12601 tacttggttc aatcgctcag ccgcttcttc cgtcaaacgg tagaattcac tatgcatatg
    12661 gtgttcttca attttatcta cgctgacagg tcggaatgta cctaacccta catgtagtgt
    12721 cagatagact aattcaacac cctttgcttc gatctcatca agtaattctt tcgtaaaatg
    12781 caatccagct gttggcgctg cagcagaacc attttctttc gcatagacag tttgatagcg
    12841 atctgggtct tccagacgtt ctttgatata tggaggcaat ggcatttctc ccaatgattc
    12901 aagaatctct agaaaaattc cttcatactc aaagtcaatg atccgtccgc cgtgttccaa
    12961 ttcttctttc actactgctt gcaatctgcc atcaccaaaa gagattcttg tcccaacttt
    13021 ggcacgtttc gcaggtttga tcaatgtctc ccacgtatct ccttgtgtat tcgttagaag
    13081 aaggacttct aaatgcgcac cagtatctgg tttttctcca tataaacgag caggcagaac
    13141 tcgtgtatta ttcataacta gcgcatcacc aggctgtaac tcttcaatga tttcatggaa
    13201 atgtttatct tccatctctc cagttttccg atccaaaaca agtaaacgag aatgatcgcg
    13261 gtcttttaat ggtgtttgtg cgattaattc ttccggcaag tcaaaatcaa aatcttctgt
    13321 tgttaacata tcgtcactca ctttctatca tgtgcttcat cattctatca tgtttttcgt
    13381 tctgttggca aaatcagcac tttttcactt ctattttttg ttttcctaaa taaaaaaact
    13441 accctatttg tattttttca ttgttttagg catactagta atagatagtt cttcattgaa
    13501 aatagaaaaa gaggtggcac catgattgaa tttcaaaatg tgtcaaaaat ttataaaggt
    13561 ggaaaagtcg ctgtagagga cgtcaatctt tcatttgaaa agggtgagtt catttgtttt
    13621 atcggtacga gcggaagcgg aaaaacgacg acgatgcgga tgatcaaccg aatgactgat
    13681 ccaacacaag ggaaaatttt gattgatgga aaatccatcc aagaaattga tccagtggaa
    13741 ttgcgacgtc agatcggcta tgttatccaa agtattggat tgatgcctca catgacgatc
    13801 cgtgaaaata tcactcttgt ccaaaaattg ttgaaagtca gtcaagaaga acggaataaa
    13861 acagctgaaa aaatgattga tcttgtggaa ttgccccgtg agatgttaga tcgctaccca
    13921 catgaattat ctggtggtca gcagcagcgt attggagtcg ttcgtgccct tgcagcgaat
    13981 caagatatca tcttgatgga cgagccattc ggtgcgcttg atccaatcac tcgtgattcc
    14041 ttgcaagacc ttgtcaaaga tttacaagag cgtttgggaa aaacgatcgt atttgtaacc
    14101 catgacatgg atga
//
LOCUS       DASHXG010000060        14077 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.061, whole genome shotgun sequence.
ACCESSION   DASHXG010000060 DASHXG010000000
VERSION     DASHXG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.061"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..345)
                     /locus_tag="U2R59_002259"
     CDS             complement(<1..345)
                     /locus_tag="U2R59_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEM8966610.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKT"
     gene            complement(696..1388)
                     /locus_tag="U2R59_002260"
     CDS             complement(696..1388)
                     /locus_tag="U2R59_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8966611.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1825..2394)
                     /locus_tag="U2R59_002261"
     CDS             complement(1825..2394)
                     /locus_tag="U2R59_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEM8966612.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2468..2791)
                     /locus_tag="U2R59_002262"
     CDS             complement(2468..2791)
                     /locus_tag="U2R59_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966613.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2945..3757)
                     /locus_tag="U2R59_002263"
     CDS             complement(2945..3757)
                     /locus_tag="U2R59_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966614.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4111..4959
                     /locus_tag="U2R59_002264"
     CDS             4111..4959
                     /locus_tag="U2R59_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HEM8966615.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5104..6045
                     /locus_tag="U2R59_002265"
     CDS             5104..6045
                     /locus_tag="U2R59_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HEM8966616.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6035..8206
                     /locus_tag="U2R59_002266"
                     /pseudo
     CDS             6035..8206
                     /locus_tag="U2R59_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(8318..10489)
                     /gene="copB"
                     /locus_tag="U2R59_002267"
     CDS             complement(8318..10489)
                     /gene="copB"
                     /locus_tag="U2R59_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HEM8966617.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10509..12695)
                     /locus_tag="U2R59_002268"
     CDS             complement(10509..12695)
                     /locus_tag="U2R59_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEM8966618.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12695..12904)
                     /gene="copZ"
                     /locus_tag="U2R59_002269"
     CDS             complement(12695..12904)
                     /gene="copZ"
                     /locus_tag="U2R59_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HEM8966619.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12917..13357)
                     /locus_tag="U2R59_002270"
     CDS             complement(12917..13357)
                     /locus_tag="U2R59_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEM8966620.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13431..13970)
                     /locus_tag="U2R59_002271"
     CDS             complement(13431..13970)
                     /locus_tag="U2R59_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8966621.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3994 a         2905 c         2467 g         4711 t
ORIGIN      
        1 tgttttatta tatggggatg ttttcgttat atataacaac ttttcttttt caattttcat
       61 taataactct gtcgaagtct gtactttatc ttgataatta aatgcagaca taccactttg
      121 tataattgta attattgctg aagcaattga aacaatcaat agtaaagacc tgtgttcgga
      181 agcctgatca attaatattg ggatactagc tgataagact atttttataa tatttccgat
      241 accaattact ctattataaa atcgaatttc tttttttaat ctatcgattg tagaatcaat
      301 agattcgata aacgcttttt gatccatcat tttctctcca atcattttat taaaatcatt
      361 aacaaaaata ttataatagg atttaagtaa gttctaacta atcacatata aaaataaaaa
      421 aacatttgta ttttatcaaa gttttattat acttgtcaat ttgtgtacat cctaaaatat
      481 aagctatttg tttacttctg tagaatatat actttgttgt tagataagtt gcacatgttt
      541 atagaatcta aataataaat ttttatgtac cgcccctcaa agtgaactga accccaaaag
      601 ttgaactatt taatggactg tttccgatat tctactggag atagtccatt aaatagttca
      661 acttttgggg ttcagttcaa agaggggggg attttttatc gttgtggaat atttaaatac
      721 caacgcttgt catgaaaatc ttgtgctcca cccttagtat ttccttctgg atcgtttgtc
      781 gcacgcatca tgacgtatac tttcttatta gggaaatcac gcatattgaa agatacatga
      841 tagccaacat ttcctaaagt attataagct tgatttacgt ctggtctata aatcccatca
      901 gctcttactc tagctagttc ttttccagta ttgtagtcca taatgaaaat atactcgtat
      961 ttataattag caatgtgcca tccagctaca tgcaagtttg cgttttcgat ttctccgaac
     1021 tgatcaatgt gggcgtaatt tgttccatct gtcagcgtag aatttgcagc acctgctcga
     1081 gttggatcaa ttactggttt atcctccgaa gtagttggat tatcatccgt aaaaccatga
     1141 gccaaatcat aggctagttt ttctttactt acacccattt cagaaagata accgtaagga
     1201 tctgtatgat cgccccaaat attttgtgtt acccataaat gcgatttgat tcctggttgg
     1261 ttataaggag tgtctaatgt taatggaata ccatatttca ttgctgaatc tcttgccaat
     1321 tcaacgtata ctttatagtt cttttcaaaa gtttctttat catgtgtatg ttgtaactcg
     1381 atttgcacag gacttttggc tcacgaggtt gtcctactct acatcttgct gatagatatg
     1441 ctgaaaggaa aacaccaaca ttatgttttg ctttttcagc tagaacgaga caagcaggaa
     1501 tacctttaga agatatcaaa ggttttttag gtcataaaga tgtttccact acacaagtct
     1561 atgcccatat ttctcccgaa gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag
     1621 aagagcaaat aaaaaagcac tcaaattgag tgctttttta agctcactat cactaaaact
     1681 atcactaatt ttatttataa gcgaacatgt ttctatcact gattttttaa atctagcgaa
     1741 aaacccttat cttaaaggcg ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg
     1801 cctagaagtg cgaacatggt tttcttatag ctcatgtaga aaaattttct tgatgatgat
     1861 tttatccatc aattgagatt gactgttttg ctctcctatg atttcagcta tgattgtccg
     1921 attttgcggt tttcttctta actggtagtt gattttccca gtttccatca actcgctaag
     1981 catatccacg actccgccaa atccggtctt tttcgtaata aaacctagtg ctaccattcg
     2041 ttcatctaga ttttttgctg taatcgtcac accagtaatg agcgagtgct gtaatgtttg
     2101 ggccagctct tccatccctt cagcattgga tacgacggaa gctgttttgt taataggttc
     2161 ttcgtttatt tcttttggtt ctttcctctc cactttcact gtttgacgaa ggacatctag
     2221 ttcttgcaag agcgtttcgt attgttcttg ggtcagcatc acgccagcta ctttttcacg
     2281 attaaatata tatacgccag ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga
     2341 tcgtttcact tctgtgatcg aagatgtggg aacttctaat ttctttaatt ccaatggatt
     2401 tcctccttta ctaatcgctt tttattatag cacagactga cttgttttga tcttttttcc
     2461 aaaggtttta tcggtttttg cctaaccagt aattgatatc ggtaagaagt ctttcgatac
     2521 caaatgaagg atggtacaga tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat
     2581 gatcgatgat cactagatct gcataccgag gcggcttatt tcgagtacat acatgtatag
     2641 agatccgttt tcgatgtctt agcgttttgt tcagtacccc agcaagtctt cttgcttctt
     2701 ggtgttcata gcgaaaaaaa aagacgattt tcacttcagg agggtggaca tctaaatacc
     2761 ctcgttcctg gagtgttttc agtaaaagca tcccccactc tactgcgggg tgtgcaagtg
     2821 cttgttggat cgctagccga aattgatata gtttatcttt ggaattggga aatttttcta
     2881 atgtttcctg ataataacga acttcttcta tcagccggtc atggatacca attacgtaac
     2941 gaagtcattc ttggtaaagt acttttgtca gctttgattt gctttcgctc tcaaattcgc
     3001 tattcagcca aaacagcgaa tcaagctttt cagtcacaat cgtcaatttc cgatagtctt
     3061 gtgtctcttc tatccgtttc caccgctttt cagtaatctg gttacagctc aagcgcaaaa
     3121 ttgctagata atttttttct tttattggca aaatctgctc ctctctaaat agcaattcag
     3181 gaaacaattc aaagaatagt gttcgactgt ctcctaaaat ctcgatttct gccggatcct
     3241 ttctttgctt caataattgg atgaacatct cagaaaagga ctgctctcca tcatctgcaa
     3301 aaaaatgcgg aaaatctttc aaaaagcaaa acagcagata tcttactttt ctttctgaac
     3361 caaagatctg tgctttttta taagaaaaag aaaggtggta ctcgccaaac cactttctca
     3421 atcgctcttg cgtagaacga tcgtacttct gctcgtaagg ttcattcaat agcagatttt
     3481 tcagtaaaca aaacgggggt gattggatca gaaaaacaaa caagagataa ggttcgctat
     3541 atccttgatc ataaactaac tgaacggttt tcttatgaag aatcagctga atgggacagt
     3601 cgctttccgc caaacgtttc agatgccgat ccactgtttt aacatcgatt ttcagttctt
     3661 cagctaaatc agcttttcgc cagatcaaat ctttcattag attgattagt gaaaataaat
     3721 tctgtgcatt ttttgataat agtttttgcc atctcatcga tcatttctca cctgatttct
     3781 aaacatattg tttgatcaaa atgggttcac tcctaaaaag ataaaaaact ccctttctat
     3841 ttatttaaat acgcaaatct tcctcattat tttttatttt actcaattta atcgtattct
     3901 catttcaaaa cgaatgtact ttaaaaaaac ataataagat cactttgctt gtaggatgta
     3961 ttcccttcca ttacaatgaa ataaatagcg attttatgag aaggtgatgt gaaaatggaa
     4021 gaaaaaatag aagaatccaa acaaaaaatc gatcagttga tataagaatt agaaaaagcg
     4081 gtcatcggca aacgttcaac tatccaattg atgatcgtgg ccctattagc aggtggtcat
     4141 gtcttattcg aagatattcc cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa
     4201 gctgtacagg gaaccttcag cagagtccaa tgtactcctg atctgctgcc tagtgatatt
     4261 cttggttttt ccgtatacaa ttcacaatca aaagagtttg aatttcgtcc gggaccgatc
     4321 tttaccacga tcttgttagc agatgagatc aatcgtacga ctcctcgtac tcagtcagca
     4381 cttttagaag caatggccga gaatcatgca acgatcgaca acaatacata ccctctagac
     4441 aatcattttt ttgtcttagc tacgcaaaat ccaatcgagt acgaaggaac atatcctttg
     4501 ccggaagcac agctcgatcg ttttttattc cgactacaaa tcggttatcc ttcttttgat
     4561 gacgaacttt tgctactttt ggataaattc gaaaaagtgt tggataactt aaatgaagta
     4621 ttgaacagtt atgaaataga agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc
     4681 gaagtggcat cttatgcctt gcagttagtg tcagcaacaa gaagtcatgc tgccatccag
     4741 cttggcatca gtccacgagg aagcctttcc tttattcagg cagcaaaagc ttatgcttta
     4801 atccatggga gaaattacgt cacgcccaaa gatttgcagg atttagttcc ttacgtgttt
     4861 tcccatcgcc tgatttttta cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt
     4921 catactcttg ttgcacaaat tcctattcct gtgaggtaga ttgaggtaga caatggaaaa
     4981 aatcaaagat tatttcatta attttgtgtt atttctggta tatttcatca ttgtgctttt
     5041 tgctcttgta ttcaacaatt ctttaggctg gttcttgttg gcctttttta ctctttatgt
     5101 atcatggagc ttgatttcat taagcagctt tctaaagaaa ctttcggtta cttgtacatt
     5161 gcagccactc gtttatcgca aaaaaagtat gcaggttatt ttttccatag caaaaaagag
     5221 aactttttct ttacctctcc ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa
     5281 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     5341 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     5401 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     5461 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     5521 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     5581 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     5641 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa
     5701 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     5761 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     5821 ttggaagctg gcgatgagaa agcttttttc gcacacttga aaaaatatgc aaaaaaacaa
     5881 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     5941 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     6001 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaacggg aaaaatggct
     6061 gcgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     6121 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     6181 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     6241 gtttttatat tttccttcga agacattttc catattatgg atcttacagt ttttttcgtc
     6301 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     6361 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     6421 ctattggtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     6481 gaaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     6541 agcaaggcaa tttttctcca tccggttgtt gtcgggaaac actcgattcc agtcattgac
     6601 tacagttctg cttatttgtt tcttaacttt tagcgctatc ttgcctttat atcttccgaa
     6661 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     6721 gctttatgac acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     6781 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     6841 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     6901 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     6961 ctaccaaacc gttatagaag acaaagaaaa cattacattg accctaaaaa aacaagtttt
     7021 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     7081 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     7141 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     7201 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     7261 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     7321 cgaagctgtc taacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     7381 cgggcatact ccaaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     7441 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     7501 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     7561 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     7621 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     7681 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     7741 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     7801 accagcttat aaaatcgtct tattcagcct tggagtgtgt ttatccgtct tgttgttctt
     7861 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     7921 tgcttctact aatacgattg catatcaaaa acttcttaac cctttggaaa cattggtacc
     7981 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     8041 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     8101 agatccggta aaattcgata aaaaaaccta tttagaaata acgcatataa taagaaaaat
     8161 ggtatacaaa aaaattctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     8221 agaatctact tctggaatgc cgagaaccag ctgattgagt atcgattact cgaaaaaaag
     8281 gttgtgacac gttttttgtc acaacctttt ttcattatta tctgattttc aatgtcaaag
     8341 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     8401 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     8461 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     8521 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     8581 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     8641 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     8701 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     8761 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     8821 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     8881 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     8941 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     9001 tcacttgttg ttttttgact gttgcctcta gcccgactcc tgaaagattt tttagatttt
     9061 cagcttgata aggcttgatt tcatgttctt tcaaataatt cataatgcca acagccaatg
     9121 gatgattggc attcgcttcc aaggctccta gatattgaag gatttcattt ttattgaacg
     9181 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     9241 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     9301 gtaatccgtt tttagctgct attgatgtgg aacgagcaac aactaatggg atagctaaac
     9361 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     9421 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     9481 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     9541 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     9601 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     9661 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     9721 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     9781 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttc actgattctg
     9841 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     9901 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     9961 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
    10021 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
    10081 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
    10141 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
    10201 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaattcc
    10261 ccatgtgcat ggaatgatcc atgccgccgt gttcgtgatc catgtgcatc gaatggtcca
    10321 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tgatccatct
    10381 gactatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
    10441 ctacttcttt tttatgctca tgttttttct ccatatcgtt cccattcatt tttactccat
    10501 cccttctctt actttttcat gtgtcgattt aagcacaggg agttcaacaa tacactgacg
    10561 gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag tgcggcaaaa
    10621 ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat ttttctcaat
    10681 gtcaacctag acaactcgat tgtttgtgca atggatgcca aactgctatt catcagcgtc
    10741 acatcggctg tttccatcgc aatgtccgtt ccacttccca ttgccatacc gacatcagct
    10801 aatgctaagg ccggtgcatc attgattcca tcgcctgcca taccgacttt tttgccatct
    10861 ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc aaagatatgc
    10921 tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc
    10981 agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt gacttctagt
    11041 ttgatttgat cagccacggc aatcaacccg atcacttgct tttcatcagc taaaaacatg
    11101 actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc aaatgatagg
    11161 ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccgtt aatcgtaccg
    11221 ctgattccag cacctgggtg ggctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc
    11281 agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg ttctaaagta
    11341 taaaaaatag ataggacttc tttagaaccg actagatctg taactttggg ctttccttct
    11401 gtaatcgttc cagttttatc caaaacaatg ctgtctaagt gagcagctgc ttctaatgct
    11461 tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac cataatagct
    11521 gttggagtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga gacactatgg
    11581 atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt gataaacgcg
    11641 atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt ttggattggg
    11701 gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac tgtctgcttg
    11761 ccgacttgtg taacttccat gtgaagtaga ccattcgtat tgattgtccc gccaaagagc
    11821 gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact ttcatctatc
    11881 gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg acggatgact
    11941 agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc gtttcttatc
    12001 acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc tgttttcgtt
    12061 tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat actgctgctt
    12121 tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag
    12181 gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcgt cttgattgca
    12241 tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc agacagcact
    12301 aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc taacatcata
    12361 gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag atcgaatagc
    12421 atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc ttcatcgtac
    12481 aaaattgcac catagccgat gttttctacg ctttggatta atttttcagt ggtcgtccct
    12541 tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac cacaccaggt
    12601 tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat acctgtaatg
    12661 acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct ttataaccca
    12721 atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca aacttgaccg
    12781 taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt gcgcttactg
    12841 tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa aattgttgtt
    12901 tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg atacagttac
    12961 attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca ttgatatctt
    13021 cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc ctttttgcac
    13081 agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc gagacagctg
    13141 gataataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt tttaccaaac
    13201 gacccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct aagatctgcg
    13261 tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc tcccactctg
    13321 aatcactgat ctttactggc gttttgactt tttccattta tttcacacct ttcgtttaca
    13381 aatgtaatca ttatcttatg aatacagatt acacttgtaa acaaaaactg tcaattattt
    13441 ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg
    13501 atcagtttat ttcttgcatt agctacttgg atcagctgct gtattttcgg ttcattgttt
    13561 tcttcaaaat gccagataaa agataaaaat tctaagtatt ccctgtttag tttctccgaa
    13621 aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag agaacgccaa
    13681 actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt atctgcttct
    13741 ttaatccttt cctctaatgt agaagtataa tttccttcaa cgatccatga cggattagat
    13801 accataaaca attgctgttc ttgcaaaaac cacttttttg cctgaatact gtagtctgtt
    13861 gtatgccata aaaggtctag cggcagtagc ggaaagtcgg tgatttcttt gatcttcctt
    13921 gcgagggtcg attttcccga cccactttgt ccaatcacga tgatcttcat tcttctccct
    13981 cacttctctt tggaatttgg ttcgatcata ccacttataa cgccgcaaaa aaacaaggga
    14041 ctgtgacaaa agtcgtgtca aagtcccttg tttcgaa
//
LOCUS       DASHXG010000061        13778 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.062, whole genome shotgun sequence.
ACCESSION   DASHXG010000061 DASHXG010000000
VERSION     DASHXG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.062"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            312..482
                     /locus_tag="U2R59_002272"
     CDS             312..482
                     /locus_tag="U2R59_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966622.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            496..1098
                     /locus_tag="U2R59_002273"
     CDS             496..1098
                     /locus_tag="U2R59_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966623.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="U2R59_002274"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="U2R59_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2102..2266
                     /locus_tag="U2R59_002275"
                     /pseudo
     CDS             2102..2266
                     /locus_tag="U2R59_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
     gene            2303..2599
                     /locus_tag="U2R59_002276"
     CDS             2303..2599
                     /locus_tag="U2R59_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HEM8966624.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2600..3016
                     /locus_tag="U2R59_002277"
     CDS             2600..3016
                     /locus_tag="U2R59_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEM8966625.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="U2R59_002278"
     CDS             3036..4580
                     /locus_tag="U2R59_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966626.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="U2R59_002279"
     CDS             4723..4947
                     /locus_tag="U2R59_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966627.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..5831
                     /locus_tag="U2R59_002280"
     CDS             4962..5831
                     /locus_tag="U2R59_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEM8966628.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5812..6546
                     /locus_tag="U2R59_002281"
     CDS             5812..6546
                     /locus_tag="U2R59_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8966629.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6579..7487
                     /locus_tag="U2R59_002282"
     CDS             6579..7487
                     /locus_tag="U2R59_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HEM8966630.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7484..8026
                     /gene="sat4"
                     /locus_tag="U2R59_002283"
     CDS             7484..8026
                     /gene="sat4"
                     /locus_tag="U2R59_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEM8966631.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8119..8913
                     /locus_tag="U2R59_002284"
                     /note="aph(3')-IIIa"
     CDS             8119..8913
                     /locus_tag="U2R59_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEM8966632.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9189..9761
                     /locus_tag="U2R59_002285"
     CDS             9189..9761
                     /locus_tag="U2R59_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8966633.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            10059..10955
                     /locus_tag="U2R59_002286"
     CDS             10059..10955
                     /locus_tag="U2R59_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8966634.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            11054..11263
                     /locus_tag="U2R59_002287"
     CDS             11054..11263
                     /locus_tag="U2R59_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HEM8966635.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11280..11552
                     /locus_tag="U2R59_002288"
     CDS             11280..11552
                     /locus_tag="U2R59_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEM8966636.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            11554..12417
                     /locus_tag="U2R59_002289"
     CDS             11554..12417
                     /locus_tag="U2R59_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEM8966637.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="U2R59_002290"
     CDS             complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="U2R59_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEM8966638.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(13542..13625)
                     /locus_tag="U2R59_002291"
     CDS             complement(13542..13625)
                     /locus_tag="U2R59_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEM8966639.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         4887 a         2136 c         2866 g         3889 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataaagaag
     5761 tgaatgaaat tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa
     5821 aacaaatatg atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa
     5881 ggactggctg gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt
     5941 aagcgtgtgc ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac
     6001 ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga
     6061 aaaacccatt ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca
     6121 gaggagagct ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag
     6181 aatttaataa aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt
     6241 gaacatcctg tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa
     6301 atactgcatt tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg
     6361 gaagaaaagg ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca
     6421 aatagtttta taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt
     6481 ccggggatgg cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag
     6541 atgtaataat atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga
     6601 tggatttagt actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg
     6661 ggtcacgcgc aaatattaat atacctaaag atgaatttca ggattatgat attacatatt
     6721 ttgtaagtga tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata
     6781 taataatgat gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt
     6841 cctatcttat gctatttgat gattacaata aaattgatct taccttattg cccttggaag
     6901 agttagataa ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta
     6961 gaattaaaag ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa
     7021 gggagtatga tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat
     7081 tgtgccgtaa ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc
     7141 tgctgagaat gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca
     7201 agaactataa gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca
     7261 cctaccggat ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt
     7321 tcagggcggt atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata
     7381 ggaatataac aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc
     7441 tggatagcac atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa
     7501 agcagggcac ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat
     7561 tataccgagg tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata
     7621 tttaaaaagc taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata
     7681 tattgacaat actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa
     7741 agttaaactg cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa
     7801 ggatttcagg gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa
     7861 gcataaaaac ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa
     7921 attctatcat aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt
     7981 tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag
     8041 tgaattggag ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa
     8101 agaggaagga aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc
     8161 gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg
     8221 gtgggagaaa atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc
     8281 tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca
     8341 aaggtcctgc actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat
     8401 ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg
     8461 tatgcggagt gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat
     8521 agcttagaca gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg
     8581 gattgcgaaa actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt
     8641 ttaaagacgg aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc
     8701 aacatctttg tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg
     8761 gcggacaagt ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa
     8821 gaacagtatg tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata
     8881 aaatattata ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct
     8941 ttaactacaa gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac
     9001 tctgatgttt tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa
     9061 agagttttgg tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca
     9121 ctaacagcag ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg
     9181 aataaaattt gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa
     9241 aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca
     9301 gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat
     9361 attttcttgt agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg
     9421 cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt
     9481 ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac
     9541 aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg
     9601 ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat
     9661 atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata tcactggggt
     9721 tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat ataggaattt
     9781 tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa gccatgatgg
     9841 ctctttggaa caaatattaa aacaaatgct ttcatataaa aaactatatg ccctacaatg
     9901 ccgttgtaaa aattggggaa aagggatata ttgattttat atctttctca aaataaatat
     9961 aaaagccctt taaagagggc ttttatatat taatcacaaa tcacttatca caaatcacaa
    10021 gtgattaatc acaaatcact tgtgatttgt gattcttaat gatacaatat tactatacaa
    10081 aaaaagaatg gggcgtagtt atggagaagg aaaaactaaa aatacttgaa gaattaagac
    10141 gtattttaaa caataaaaat gaagcaatta ttatcttgaa taattacttt aaaggtggtg
    10201 ttggaaagtc caaattatcg actatgtttg cttacttgac agacaaattg aatttaaaag
    10261 ttttaatgat cgataaggac ttacaggcaa cattgacaaa agacttagca aaaacttttg
    10321 aggtagaatt gccacgtgtc aatttttatg aaggcttgaa aaatggaaac ttggcttctt
    10381 ctattattca tttgactgat aatttagact tgatccctgg cacgtttgat ttgatgttac
    10441 tgccaaaatt aactcgctca tggacgtttg aaaatgaaag tagattgctt gctactcttt
    10501 tagcaccttt aaaaagtgac tatgatctta ttattattga tactgtacca acgccaagcg
    10561 tttatacaaa taatgcaatc gtggcgagtg attacgttat gatcccttta caagcagaag
    10621 aagaaagtac aaacaacatt caaaactata tttcctattt gattgatttg caagaacagt
    10681 ttaaccctgg actagatatg attggttttg ttccttattt agttgatacg gacagcgcaa
    10741 cgataaaatc aaacctggaa gaactgtaca aagaacataa agaggataat ttggttttcc
    10801 gaaatattat caagcgaagt aataaagtaa gtacttggtc taaaaatggc attacagaac
    10861 acaaaggcta tgacaaaaaa gttttgtcta tgtatgagaa cgtatttttt gaaatgattg
    10921 agcgaatcat tcaattagaa aatgaaaaag aatagaatca caaatcacaa gtgattaatc
    10981 acaaatcact tgtgatttgt gataggtgat gataaaataa atagtaagaa gaaatagaaa
    11041 gaagtgagcg atcgtgggaa atttaggcgc acagaaagca aaacgaaatg atacgccaat
    11101 cagcgcaaaa aaagatataa tgggggataa gacggttcgt gttcgtgccg acttgcacca
    11161 tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta tggatcaagc
    11221 cttagaagaa tatatacgga aatatttacc tgacaaactt taaaaggagt gaaaatgaaa
    11281 tggcagttac gtatgaaaaa acatttgaaa ttgaaatcat taatgagtta tcggcaagtg
    11341 tttataatcg ggtattaaat tatgttttga atcatgaact agatactaaa aatactcgtt
    11401 tactagaagt gaatctttta aatcaattag aagtggcaca agaagttgat ttatttcaac
    11461 aaccatttga agaattacaa gctattcatg agtattggcg gtcaatgaat caatattcaa
    11521 aacaaatttt gaataaagag aaagtggctt aacatggcga atattactga cttcaccgaa
    11581 aagcaatttg aagatcgttt agaaaagaat gttgaacgac taactaaaaa tagactagcg
    11641 gttgaatcgc caaccgcttt tttacttggt gggcaaccag ggtcagggaa aaccagtttg
    11701 cgatcagcaa tttttgaaga aacacaaggg aatgttattg tcattgataa tgataccttt
    11761 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
    11821 cacgttaccc cttattcgaa tcgcatgaca gaagcactta ttagccgttt aagcgatcaa
    11881 ggctataatt tagtgattga aggaacagga cgaacaacag acgttcccat tcaaacagcc
    11941 acaatgcttc aatctaaagg ttatgaaaca aaaatatacg tcatggcagt accgaaaatt
    12001 gaatcatact taggaacgat tgaacgatat gaaaccatgt atgcagatga tccaatgaca
    12061 gctagggcaa caccaaaaca agcgcatgat attgttgtca aaaacttacc gaccaattta
    12121 gaaacccttc ataaaacggg cttatttagc gatataaggc tttacaatag agaaggagtg
    12181 aaactctatt caagcttaga aacgccttcc attagtccga aagagacctt agaaagagaa
    12241 ttaaatcgta aagtatcagg gaaagaaatt caaccgactt tggagagaat agagcaaaaa
    12301 atggttcaaa atcaacacca agaaacccct gaatttaaag caattcaaca aaaaatggaa
    12361 agcttgcagc tacctacacc accaataccc aaaacaccta aacttccagg tatttaaacc
    12421 ttaaaaaagg aaaagagtag ttaccaaaaa acggtaacta ctcttttttt ataaaaacat
    12481 ttcctcatgt tggggtcccg agcgcctacg aggaatttgt atcgataaga aatagattta
    12541 aaaatttcgc tgtttttttc taatttcatt ttgaggtgaa ttaattggta gttattagag
    12601 gtgccctata cctaataatt tatctacatt ccctttagta acgtgtaact ttccaaattt
    12661 acaaaagcga ctcatagaat tatttcctcc cgttaaataa tagataacta ttaaaaatag
    12721 acaatacttg ctcataagta acggtactta aattgtttac tttggcgtgt ttcattgctt
    12781 gatgaaactg atttttagta aacagttgac gatattctcg attgacccat tttgaaacaa
    12841 agtacgtata tagcttccaa tatttatctg gaacatctgt ggtatggcgg gtaagtttta
    12901 ttaagacact gtttactttt ggtttaggat gaaagcattc cgctggcagc ttaagcaatt
    12961 gctgaatcga gacttgagtg tgcaagagca accctagtgt tcggtgaata tccaaggtac
    13021 gcttgtagaa tccttcttca acaatcagat agatgtcaga cgcatggctt tcaaaaacca
    13081 cttttttaat aatttgtgtg cttaaatggt aaggaatatt cccaacaatt ttatacctct
    13141 gtttgttagg gaattgaaac tgtagaatat cttggtgaat taaagtgaca cgagtgttca
    13201 gttttaattt ttctgacgat aagttgaata gatgactgtc taattcaata gacgttacct
    13261 gtttacttat tttagccagt ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa
    13321 cggtatcggt ttcttttaaa ttcaattgtt ttattatttg gttgagtact ttttcactcg
    13381 ttaaaaagtt ttgagaatat tttatatttt tgttcatgta atcactcctg aagtgattac
    13441 atctataaat aaatacagaa gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa
    13501 agtcataaga ttagtcactg gtaggaatta atctaacgta tttatttatc tgcgtaatca
    13561 ctgtttttag tctgtttcaa aacggtagat gttttatcta cattacgcat ttggaatacc
    13621 aacatgacga atccctcctt cttaattaca aatttttagc atctaattta acttcaattc
    13681 ctattataca aaattttggt tctgttgcaa agttttaaat ctactatcaa ataaggtaga
    13741 ataatagaaa aagatagcag gaggaatgac gatgaatc
//
LOCUS       DASHXG010000062        13734 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.063, whole genome shotgun sequence.
ACCESSION   DASHXG010000062 DASHXG010000000
VERSION     DASHXG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.063"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(63..1268)
                     /locus_tag="U2R59_002292"
     CDS             complement(63..1268)
                     /locus_tag="U2R59_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEM8966640.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="U2R59_002293"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="U2R59_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="U2R59_002294"
     CDS             complement(1447..2832)
                     /locus_tag="U2R59_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEM8966641.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="U2R59_002295"
     CDS             complement(2861..3247)
                     /locus_tag="U2R59_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8966642.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="U2R59_002296"
     CDS             complement(3263..3577)
                     /locus_tag="U2R59_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8966643.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="U2R59_002297"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="U2R59_002297"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEM8966644.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="U2R59_002298"
     CDS             4837..6126
                     /locus_tag="U2R59_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEM8966645.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(6165..6770)
                     /locus_tag="U2R59_002299"
     CDS             complement(6165..6770)
                     /locus_tag="U2R59_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HEM8966646.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(6966..7430)
                     /locus_tag="U2R59_002300"
     CDS             complement(6966..7430)
                     /locus_tag="U2R59_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEM8966647.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(7452..7772)
                     /locus_tag="U2R59_002301"
     CDS             complement(7452..7772)
                     /locus_tag="U2R59_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEM8966648.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="U2R59_002302"
     CDS             complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="U2R59_002302"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEM8966649.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            9194..9544
                     /locus_tag="U2R59_002303"
     CDS             9194..9544
                     /locus_tag="U2R59_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEM8966650.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            9729..10682
                     /locus_tag="U2R59_002304"
     CDS             9729..10682
                     /locus_tag="U2R59_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8966651.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            10695..12482
                     /locus_tag="U2R59_002305"
     CDS             10695..12482
                     /locus_tag="U2R59_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966652.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            12469..13671
                     /locus_tag="U2R59_002306"
     CDS             12469..13671
                     /locus_tag="U2R59_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966653.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         3937 a         2689 c         2521 g         4587 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt gaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aaagaggttg tgacaaagac ttgtcacaac ctctttattt tggaaatact
     6181 tctccgacta cggcatcctc aggcaatact aagattcctt ttttttctgg agcatttggc
     6241 aaatgcaatt cacgagcaga acaaatcatt ccatagctgg ctacccctcg caaagttcct
     6301 ggccagatca tcattccatc tggcatcatg gctcctggtt ttgcaacgac aactttttgt
     6361 ccagcttcga tatttggtgc accgcaaaca atttgcaata ctgtcccatt gtccacttct
     6421 gtctcagtaa tcgataaatg gtcagagtca ggatgcggga cgcatgtttt tacatacccg
     6481 acaacgatct tcggttcatg atcagcttca agctgttctt cgaatcctgc ttctttaatc
     6541 aatcgattca atttcgctaa ttcttcatct gttaagctta cttggccgtt cccttcaatt
     6601 gttagatgat cggagatatg gaaaaagttc caagcaacaa cttgaccttg ttcatctttg
     6661 atccgagcaa cattccattt acgttcgaca gtgttttctg ttcctttatc gtcggctatg
     6721 ataaccatca aagtgtctcc gacgtgtgct ttgttataag caaaaatcat gttctttcct
     6781 ccattatcct ttgctgagat ttatcttaac aaaaaattgc attcactgca tgagattttt
     6841 ttcatgcttt atttccgaag aagcttcttc tggaacacca tttattcgta acaagggact
     6901 gtgacaagac ttttgtcaca gtccctttac tgtttgatta aaaaggttat acaagttcca
     6961 cttgcttaat tactcggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa
     7021 tgacgtatga cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagtcca
     7081 gactgcccaa ccatgattag atcgattgca tatttttttg gcaatttgac tgccatggat
     7141 tcacgaacag agccgtatgc aataattcct tctatatttg tgtaatcaac agattttcca
     7201 tattctttac attcttcgat catttgcttg gctgtttcag tttgctgatc gactagattt
     7261 tgatcaatag gagcatagcc cataaaatta taaaattgct gatcgattac gtttgctaca
     7321 tatactttcc cattattacg gcgagccact tctaacgctt ttttgaaagc agcaagtgct
     7381 tgttcactac cgtcaatacc tactaaaatg ttcttatatt cttgattcat cttgacccct
     7441 cctaacagat gtcagccttt tattacactt tctaggaacg attcgatttc ctgttttgtt
     7501 ttacgatctt tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt
     7561 gggataccaa aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca
     7621 ataaattgcc aatcagaaaa gtcattttcg atttcaggca tttgcggttt gataaaacgg
     7681 cagtctccgc accagccggc agtaaagaaa aatacacttt ttccagtttc tacgtagcct
     7741 gctaattctt ctaaactatt tgggataatc attctttttc ctctactttc tgtttatgta
     7801 tttttcaatt aaattataca cctttctttc gaactaacaa acattgatcc tctttttata
     7861 aaaaaaatct gacaaaaggt tgcttttgcc agattttata gtttcactat cgcgttattt
     7921 cccgtatacg atcgtgttca ctgttgattt atctaaacct ttcaatgttt gaatcaacat
     7981 ttctcgtgca gcttcaaaat cgcgaatact gaacatcgtt tgatgcgtat ggatataacg
     8041 tcccactacg ccaatcactg tacttgggat tccttcattt tgtgtatgag cagcacctgc
     8101 atctgtaccg ccttttgaaa caaagtattg ataagggatg ttgtttgttt cagcgatatc
     8161 tagcaagtac tcacgcaaac gaggaagcat gatcaaacct ggatcttgga tacgcatcaa
     8221 tgtaccttct cctaaatgtc cgaatgtgcc atttttcgtc actgtgtcat ctgctgcaga
     8281 gcagtctact gcaaagaaca gatctggctt gaatttattg acagaagctt tagaaccacg
     8341 caagcctact tcttcttgga cattcgcgcc tgcaatcaat gtatgaccta atgtttcatt
     8401 ttgtaacgct tctaaagctt ctaataccat tgtacagcca tagcggttgt cccacgattt
     8461 gctgatgata ttcttcccgt tggctgtttt gatcgtttca gcgtaaggaa cgattgtgtc
     8521 tcctggaaga acaccgtaac tcattgcctc ttctcttgat tcaaacccag catcgaacaa
     8581 aatatctgtt acttctactg atttttgtcc gcttgttcct cgtaataaat gtgggggaac
     8641 ggaagaagaa atacatggat aattcttacc agtagaggtt ttaagtgtaa aacgttgagc
     8701 agaaacaacg taagggttcc atccgcctag aggtacgact ttaaaaagcc cgttttcttg
     8761 gatttgtgtc agcatgaatc cgacttcatc catatgtgct gcgaccatta cacgaggtgc
     8821 atccgcttct tcatggtggc gcagcccaaa aatgccgccc aaaccatcta actgtaactc
     8881 atctaccagc ggttccatat gactttccat ataggcgcga acgtcttgtt caaaaccgct
     8941 tgttccttgt aattctgtta actctttgat tcgttgaaat gttttttctt ccatatgcta
     9001 ttcgtctaaa tttcagacta aactcctctc agacttatat tgatctgcgg ataaaatatg
     9061 attttttctg cagaccgatc gtatttatta tagcttattt tttctggtag cggttattta
     9121 tttcaaagaa aatatgagag tgtggtaaaa taaacacaaa gagtagcaag tgagaagaag
     9181 gaggtatatc cacatgtatg aagaaagcga attaagctat tttaaaggcg ggttagccgt
     9241 tgggatcggt ctaggattat tgagtggggt agcttcaacg atttggtatc atcgcaaaaa
     9301 agtgttatca gcagaccaag tgcttgaaaa tatcaaaaca tcttttttaa aagaaggcgc
     9361 aatcgaaggt gcttggatct cttttgaaaa agaacctatt cggaaattcg ccgttcggtc
     9421 gagtgcttat cggggtgggc tttcccggat agaagatggc gaaactgttt attatgaatt
     9481 tttagcagat gctcatacag gaaccgtatt agacatttca agaaaaaagg gcgcaataga
     9541 ttaatacgtc aaaaaaatga aataacgaat acgcacccac tatctaaaag agaggtatcc
     9601 tatccttctt ttatagtggg tgatttttat aaaaataggg ctatttcctc ttggaatagc
     9661 tagtatttgt agttattata cggtattctt gaaataagat tagttttatt atataaggag
     9721 agtgacaaat ggaatcacgt gaaaaaattg ccgtgctcat tccttgttat aacgaagagg
     9781 cgacaatttc aactgttatt gaagatttta aaagggaatt accagaagca gatatttatg
     9841 tctatgataa taattcgacc gatcgaacat acgaattggc cgttcaaggc ggagcaatcg
     9901 taaagaaaga accacgtcaa ggaaaaggga atgtaatccg tcaaatgttt tttgatattg
     9961 atgccgatta ttatttgatg gtagatggtg atgatactta tcctgcagaa gctgcacatg
    10021 gtttgcttga gaaattacgt tctggcgaag cagatatggt cattggcgat cgtctatcaa
    10081 atggaaccta ttttgatgaa aataagcgtc ctttccatga ttttgggaat aatctggtta
    10141 aaaatacaat tacttactta tataaaacaa aaattcgcga tgtcatgacc ggctatcgag
    10201 gattcaatcg aatttttgtc aaaagcttcc ctattatgag ttctggtttt caaatcgaaa
    10261 cagaattgac gattcatgct ttagataaaa aattcaagtt cgttgagatt ccaatcgatt
    10321 atcgcgatcg tcctgaaggt agcgaatcaa aattgaatac attctctgac ggattcaaag
    10381 tgatcatgat gatcatcaaa atgtgcaaag attataaacc tttgcttttc tttgggatct
    10441 ggaccatctt cttcttttta tttggattgg tcatggggat tcctgtgatt cgtgaatata
    10501 tgctgacaag ctttattaca cgcatccctt ctgcgatttt aagtactgga ttgatgactt
    10561 tagcccttct ttcattagta acagggttga ttttggatac ggtcgtcaca aatgccaaga
    10621 aagaatatga attgaattta taccatgtct accacgaata tcaaaataaa gaaatgaagt
    10681 aggaggcctt ttttatgcat aagaaaaagg agaatctatt tcctactttt tttgcaactt
    10741 tatttgcgtc aggttttgct ttttttactt cttatggtct aggaactttg aatccaacag
    10801 taatcattgg tttagccatg gttttgctac ttgcttttaa gcaatatgga atagagttgt
    10861 tttcaataaa aaacaaagtt gcagctattg cccgattgtt tttttctgca gcttttgctc
    10921 ttacactttc tattggcaga cagatacaat ttcagtatgt ctcagcaaac tatacaaaga
    10981 caacgattgc tgatggaagt attttttact ttcttgttta tttctccatt tttgtgtatt
    11041 cttttttatt tttacaatcg atttatttat caatgccaaa actggaaaca ttttttactg
    11101 ctcaaaacac acaggctttc tcttcaagaa aatatttttt attctttact gtctttttag
    11161 ttctgtgttg gcttccttat ctgttggcat tgtatcctgg agtggttttg cctgattcgt
    11221 taagttcggt cgcccaatct atgggtgatg ttcctataag caatcatcat ccagtcttat
    11281 tcaccttact ggtcaagcta tttgttcatg atttaccaac tgatacgatc aatcacggtg
    11341 tatttttatt ttcgattttt caaacattga taacagcttc agcgataagt tattctcttt
    11401 gctggctgtt aaaaagaaac atccattttt ttccggtact cattagttta tgctattttg
    11461 catttgcacc ggtttttcca atctacgcct tgaacatgca aaaagatact ttgttctcta
    11521 tcgcttgctt tttattttcc ttagcggttt ttgactttat ttttcaacga gaaaagccaa
    11581 cgattctcaa tcagatttac gtaatcatcc ttgctttact gaccacctat ctaagaaata
    11641 atgggattta tgtagtaacc ggcacaggtt tgatttgcgg cttgattatt ttgaaacaaa
    11701 aaaggtatca agcattcttt caagtggtgc tgggttatac agtgattgct ggactactca
    11761 tccacccgtt gatggctcgt tatgctattc ctacagaaac tgctgaacaa ttaggtgttc
    11821 ctttgcagca aatttctaga actattgtta tggatggtga cttgtctaag aaagataaag
    11881 cattcatgaa tcagctactc ccgataaaag attatgaagc gtattctcct agtcttgcag
    11941 actcaatcaa gtggcataaa aattttaaca atgagttttt gaatacacat aaaaaagaat
    12001 ttctatcact atgggcaaga aatttaccaa gtaatataaa aatctataca gatgcttata
    12061 ttttagaaac gttcgggttc tgggtacctg gtacaaaaaa tagttacggc tttttagata
    12121 ctcgtgtaaa cacgaataat tatggtatga agcaagtaga tttgattgaa catcttactg
    12181 gattgtcagg aatgaaaaaa atcatcgatg ctcgtgattt ctttggttcc ggcacattac
    12241 tgtggttagc tatcggcagt gcacttttag caatctttaa gaaaaaatat cggtatttac
    12301 tcctttttct tcccggtatg cttgtttttg ctactattat gattgctact cctgtggctt
    12361 ttagtttacg gtatgtgttt gttttagcat taggtctacc tgtttatatc ctctctcctt
    12421 ttttactaga taaaagagaa aaaatgaaaa cagatatagg agatactcat gaaactattt
    12481 aaaaagatat tttttgcttt tgttctcttg atcgctagct attgcgtact actgacaatt
    12541 acttttttca ttccgcagca ctctattgaa tcgaatgcag aaaaatctct acagatggtt
    12601 gaaaaagaag gaatgtatcc ttctatcaat caaggaaata tgctaggcac tcggttagat
    12661 aattttactg atcatttgat gatacgaaaa acaaaagcag atcctgaatt gaactccttg
    12721 gagaacgcga tgtctatggc ggattatccc cgttattggc atggttatca gcttttttta
    12781 cgacctttac tgctagggat gagtttgggg agtattcgaa tgatttacgc agccattctt
    12841 tttctgctga ttggattgac gagctacttt ttaaccaagt gtagcgacat ctatttaacg
    12901 acagccttgt tgatttcgct tgctatagga aatgctgcaa cctttttctt cagtatgcaa
    12961 ttttcaaata tttggatttt gactttattg tctgtattac tatttttaac aaaaccacaa
    13021 ctctccaaca ccaaccaaca attattcttg tatttctttg tcattggttc tttagctaac
    13081 ttttttgact tgttgacaac accggtcatc tcttggggga tacctgtgat cattatttat
    13141 tatgtaacaa ataagtattt aatggataaa cgcagttcat tgagcaaaca agtaggcagt
    13201 tttgttttta ccggtatctt ttggggatta ggctatggtt tgacatgggt ggctaaatgg
    13261 atcctatcat cgatcatatt gaacaaaaac attgtaaaag atgcaatcaa ccaaatcctc
    13321 tttcgaacgg aaggaaacga caaatacccg ttgcatcgat tagagatgct gaaaagcaat
    13381 attagattga tgtatccaaa agtagcaata ttattgctat tgattacttg tcttgttttt
    13441 ctctattttg cttatcgtaa acgaaatagc tggcgtccgt tccaacttct agttttgttt
    13501 gttttagctg ctgtaacgcc gtatatttgg tacaatattt tagctaatca ctcacagatt
    13561 cattattggt ttacgtatcg tacgcaaatc atcacaagtt ttgctatact tagtgctttc
    13621 gcctttttga tccctcctga gaaatcaaaa gacgaactaa attactttta agaataccga
    13681 tgtactaatt catttttaaa cataaaaact ccagctgtca gagatagccg gagt
//
LOCUS       DASHXG010000063        13600 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.065, whole genome shotgun sequence.
ACCESSION   DASHXG010000063 DASHXG010000000
VERSION     DASHXG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.065"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(115..1245)
                     /locus_tag="U2R59_002307"
     CDS             complement(115..1245)
                     /locus_tag="U2R59_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEM8966654.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1786..1992)
                     /locus_tag="U2R59_002308"
     CDS             complement(1786..1992)
                     /locus_tag="U2R59_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966655.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2008..2622)
                     /locus_tag="U2R59_002309"
     CDS             complement(2008..2622)
                     /locus_tag="U2R59_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEM8966656.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2769..3452)
                     /locus_tag="U2R59_002310"
     CDS             complement(2769..3452)
                     /locus_tag="U2R59_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEM8966657.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3561..4019)
                     /locus_tag="U2R59_002311"
     CDS             complement(3561..4019)
                     /locus_tag="U2R59_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEM8966658.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4103..5866)
                     /locus_tag="U2R59_002312"
     CDS             complement(4103..5866)
                     /locus_tag="U2R59_002312"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HEM8966659.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6087..7547)
                     /locus_tag="U2R59_002313"
     CDS             complement(6087..7547)
                     /locus_tag="U2R59_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966660.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7755..8681)
                     /gene="glsA"
                     /locus_tag="U2R59_002314"
     CDS             complement(7755..8681)
                     /gene="glsA"
                     /locus_tag="U2R59_002314"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HEM8966661.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8704..10131)
                     /locus_tag="U2R59_002315"
     CDS             complement(8704..10131)
                     /locus_tag="U2R59_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8966662.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10162..11376)
                     /locus_tag="U2R59_002316"
     CDS             complement(10162..11376)
                     /locus_tag="U2R59_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HEM8966663.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11717..11959)
                     /locus_tag="U2R59_002317"
     CDS             complement(11717..11959)
                     /locus_tag="U2R59_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8966664.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(11991..12548)
                     /locus_tag="U2R59_002318"
     CDS             complement(11991..12548)
                     /locus_tag="U2R59_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEM8966665.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12561..12749)
                     /locus_tag="U2R59_002319"
     CDS             complement(12561..12749)
                     /locus_tag="U2R59_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEM8966666.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12762..13328)
                     /gene="amaP"
                     /locus_tag="U2R59_002320"
     CDS             complement(12762..13328)
                     /gene="amaP"
                     /locus_tag="U2R59_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEM8966667.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4066 a         2810 c         2219 g         4505 t
ORIGIN      
        1 atgatttttt gagatacttt cattgcgaat tcctctttct aaaagaacct ctcgcttgaa
       61 aaataaaaga ttgtacttta tgataattca aactgagagt ttctcagttt ctctttattg
      121 tttttcaggt cgatagagcg ccaactcttc ggcctgtatc tttgaagaaa tattcaacgt
      181 gattccgatt cctaaagaaa ggatcagata acttgttcct ccgtagctaa caaatggcaa
      241 tggcacacca gtcattggca tcagccccgc gatacttccc acgttcatta tcgtctgaac
      301 gaatagcaaa gttccgaatc ctaaaagaaa caatccagct tgctgatttt tacagcgact
      361 gcttaaacaa aagattctca tgcataatga gaacaataag aaaagcacac acaatgcacc
      421 gattagccca agctcttctg taataatcga aaaaataaaa tctgtttctg tctctggaag
      481 ataccctttt tttgtgatac tatttcctaa tccccgccca aatatgccac cattatatag
      541 tgcataaaac gaatgggtca tttgatagcc cgcaccatga ctatcgataa aagaatctct
      601 taaagtcgcg atcctttcat aagcatgatt aaacatctgt ggaagccaac ctttatttcc
      661 taaatataat accccgcctg ctgctccaat cagcaatgca gaaaaagtaa cgattagata
      721 gatccctttt ttaaatggaa ccgccgctgc ccaaaatatg acccacgcaa tcgaaaggat
      781 catcaatgct ccagcaatct ttggctgaaa taaaatcaga aaagttatac ctactgtaat
      841 caggaatggt ttttttagat cttttgggct actatttccg tcacgaaaaa accagcttaa
      901 ataaaaaatc aaaaaaagat ttgccagttc agaaggctgg aattgaatgc caaacagaga
      961 gatccaacgt tgtgcgccgt tgacagtgac accgaatatc cctattctta ctaatactaa
     1021 aaagaaaatc gataaggcta aaccgtatcc tgctatttta gggtgaagta aatagtgtag
     1081 tttgactgaa cgagctaaga agatcacgct ccaactcaaa aatatgaaaa ttagttgacg
     1141 caataataga ctttttgtat tttcatcggc ttgcaataaa cgataagaac tggcactgta
     1201 tacttctaaa agaccgatca tggacaaagt caaataagga cccaaaatcc accaatcgat
     1261 cttttttcac cgcatctcct cctcacacag caatccactt gtcaggtgag gagcgagttt
     1321 gtctcatcaa ataagtcagt cacaaaaata taaagaaaag gtcagaaacc ttttcgaaca
     1381 agaattctga cctagcatca tctcatcgtc cgagttttag cactatacaa cgtaaagaaa
     1441 acattcttag ctattggaaa aagccttaat ccaacagttt ctgttttacc cattggcgac
     1501 tttcgacgtt tctgggcaac agcctatgtt tgtataggag cctcacctaa caaggttatt
     1561 actatattct atttacgagt tcatgataga cttttcctaa tgattaggca atggaatttg
     1621 aaatgaaata gtgaaattta acaatcttta atatttttta gaaaaaaata acaaataagt
     1681 tgaaagaatc ccgttgcaaa ttctttcagt tgcaccagga ttctttgata attttttatt
     1741 tttatgtgtt tttttatatg ttttttcact tttcggaata aatatttatt tgttaaagta
     1801 attaaacaat ccgctaatcg tttgatctgg catttctatt tccttaccat ctaaagtaac
     1861 agtagtaacg acaaaatggt cttgcaatgg cggaacttct aagtactgcc cttgcagaaa
     1921 atcattcact gtttcatatt cttttttcat ttcttttgaa tctgtcgatg gtttatagct
     1981 tatttttaac ataactagtg ctccttttta ttcgggacgt gcaatcgtga aaatttctcc
     2041 tattgctgca taatcatttc ctgccaaacg gcttacagca ttcaattttc ttggatcgat
     2101 ccttcctgtc ttatcatcat agactgtttc atttaaatga tatttctgta cttctagcaa
     2161 aaataaatca gctgttactt tatttttatt ccgtatctcg acatgttcat ataaggatgt
     2221 ttcaaaacga acttttgctt ctgtcaatgc tggtactgaa atgattactg aatcagttaa
     2281 agtcaagtca gtcaggtaca gttcgctttc ctcattaggc agattggctg ctgttttatt
     2341 tacttcttct acgttgtcct catcaaggat atggataaca gcttctcttg tctcaagaat
     2401 attctttgct gtgtctttta ctgcatcttg ttttctctgg atcgccaagg ataagatggg
     2461 tcgattcgaa ctgacgatat tgaagtaact gaagggtgcg atattcacta tatcttttgc
     2521 tgatttagtc gttactactg ctactggtct agggatgact gaaccaatca gcaacttgta
     2581 attttcacgt tctgtcaatt ctgaaggact ccgttcaaac atggtttcgc cttctttcta
     2641 taaaattcgt taaaaagcag atcttgaaga caaaatgaaa agtaatgctt ttttcatctt
     2701 cttagaatct gctttaaact atctatcaat ttttcttttt tgtcaagaat ctgtgccgtg
     2761 cgtgtttttt agttatttgc tttacttgcg gcttcgacat atcttttagt gatcaattgc
     2821 ggacgggtga taatagatcc aactacgact gaaaaagcac ctaattcata tgctttctct
     2881 acttgttcag gagagtcagt atgtccttcc ataattactg ggatatcgac ttgttctatg
     2941 atttgattca ataaatcaaa atcaggtgtc tgcgtctttc gtgaatattc tgtatagcct
     3001 gctaaagtcg tagacaaaag atcaaaacca tcttcttgcg cttgaagcgc ttcctcaaaa
     3061 gtcgaaatat ctgccatagc taaccgaccg tgttcgtgaa tcatttggac aagttcagca
     3121 gttgtttttt ctgtcggacg tttacgagaa gttgcatcca gtgcaatgat ttctgcttgc
     3181 gtctccaaaa gttcttccac ttctttttct gtcgcagtaa taaacacttc tgacccatcg
     3241 taatctcttt tgataatccc tattaccggt aaatcaacga ttcgcttgat ttcattgata
     3301 tcttctgtcg tatttgctcg aataccaact gctccgcctt cttttgcagc caaagccatt
     3361 ctccccataa taaaagaact gtgtagcggc tcgttttcca aagcttgaca agaaacgacg
     3421 actccgcctt tgatttgttc cagtgtatcc acaatatctc ctccagtaat gttatataaa
     3481 aatacagctt catataaaaa tgtaaccctt ttctattcag gagacaataa tgagctattt
     3541 ctttcagcag acctttctta ctaaaagaaa attacttcaa attcttcgta tacgaccagc
     3601 ttctcttctg taaattctat gttcaacgct tctttataag catgtttaaa aaactcagca
     3661 tggactttcc gccaataagc taatgtccga tccccttctc cttctttcca agcatgctct
     3721 ttcgtgactt cactaaaagg caagatggtc acatttatat ttttgatgat acaaactggt
     3781 tcattttttc cattcaggac cacgtctaat tgaccaactt ttggtaaagg ctcattctct
     3841 tgtttataca gatcgtaacc acttgatgta ccagtcttta tcttttttac aactagttcg
     3901 ctcaactcgt ctgccatttt ttctgtatcc ccaaatgaaa agaaacctaa tttttctgat
     3961 tgataactag gatatttttc ttggaacttt ttgacatatt cttctacttg ctgatacata
     4021 acatccaccc ctttgctttt tataatgaaa aaaccatcca gatactagta taaacaatta
     4081 tctggatggt gagcataatg aattattgaa tattcaagac acgcagacta tcttcaacga
     4141 tttgttttgg tgttaaatga taacgttcat aaagctgccc tacaggaacg ctatccgtga
     4201 attctttctc tgcaccaaaa tttaatacgt tcattgaaga atcaccataa taacgactga
     4261 tattttcgcc aaatcctcct gacaaactac catcttctaa tgtgatgact aattcgtgtg
     4321 tttcttttaa tttatctaat gtttctacgt cattttctgt gatcgttcct ggattgatca
     4381 acgttgcttc gattcctttt tttctaaaag cttttactgt ttcttttcct aattcaagaa
     4441 aaccgcctaa agctaaaatt gctacttttc ctccattatt tactgtttga taggctggaa
     4501 tactataatc atttgcgata gctgtaccat gttctacacc atgtgtagga attcggattg
     4561 ctacaggctg cgctgtttgt tcgaacgccc aatctagcat agagatcata tcctcttttg
     4621 ttgctggagc aagatatttg atgttcggga tacttgataa gtaaggaatg tcaaatgttc
     4681 cttggtgtgt tcggtcacta gctgagatcg ttccgccacc gactaaaata atcactggat
     4741 tctcgttgat cgctaaatca tgtgataatt gatcatatgc ccgttgcaag aaagtacttg
     4801 attggaagac gactggacgt actccctgag aagccaaagc agaagcgaaa gtgatagagt
     4861 gctgttcagc gatccccacg tcaaaataat gatctggatg tttttcttgg aatgttttca
     4921 gtccaaaggc gcctggtatc gctgcattga ctgcggcaat aggagctgta cttgtttgca
     4981 ttttcttatc caaataatcc atgatgatca tattaaatgt ttctccagaa gttacttgct
     5041 ttgcctcccc ggtggacaga tcaaatggta catgccaatg atatttcatt ttattatcga
     5101 ttgccggctg ataaccgcga cctttttccg tatggacgtg aagtacaatc ggatgatcaa
     5161 tatcttttac ttcttcaaat aaacggatca ccgtttccag atcgtttcca ttatccacgt
     5221 aacgataatc aaatcccatt gctttaaata ggttattgct gcttttaccg ttggtttgac
     5281 gaagctcagc taagttttta tataaactgc catgattctc atcaatagac atctcattat
     5341 cgtttactaa tacgattaga ttggattgta aaacaccacc attgttcaat ccttcaaaag
     5401 ctaagccacc acttagggag ccgtcaccga taaatgctac cacatttcct gattctttct
     5461 tcagatctct cgctttagct aaacctgttg ctaagctgat agatgtagat gtgtgcccca
     5521 ctgtaaaata gtcatgttta ctttcatgtt ggttggaata tccgctcact tcacggtaat
     5581 gtcctttttc aaaaccattt tttcgaccag ttaaaagctt atgaccataa gactgatggg
     5641 aaacatccca aacgatttta tcctttggtg aatcaaatac ataatgaaac gcaatcgtta
     5701 attctactac acctagattc ggaccaacgt gcccacctac atcgctgtcc ttttgcaaga
     5761 ttttttggcg catctcttct gccaactgtt tcatttcctc aacagataat tttttgacat
     5821 ctgcggggct attgattgca tccaatacat gtaatactgt actcataata cattctctcc
     5881 tccgtactat cttcttttaa tgaaaataga tttgttacac tttatctatt ctactactta
     5941 gagttgactc taagtcaata gcattttaaa aaaatttcag agaaagcttg ttatataagt
     6001 agatcttcgc acgaatcagg actcaaataa aaaccttcta cagacaatta aaaagctttg
     6061 tagaaggtct cctaattaag gtctcatcaa gaaatatgtt tttttaatag gtgaagttcc
     6121 tgagcaatat gatacaaatg gatgtttgca ccttttaatg agattggata gatctttgtc
     6181 ttttcagttt ctaatccatt ttgatagcta gcagcatcgc acaaaaccac tctttttttc
     6241 gcacatagac attcatcagg caattcttct aatgaacgaa ataaaatagg atttatttca
     6301 gcgatgcctt cttccgcata caaatgaaat tgggttcgat aaaaaaattg tttgactgaa
     6361 ctttctgaaa caacaaaaat ttctatttcc tgtctccccg cttgttcact gttgatcaaa
     6421 gaaagacttt tgacgaattt tcgaatgaaa ttttcattcc atcttagttg gatttgattt
     6481 ttctttttcc actcttccaa tatttctaca atttttccgt acagaagttg ttctttttct
     6541 gatagaagat agatcctttc cggtaaaaat acttgtccat ctgcccacaa cgtacggaca
     6601 aattgtaaaa aggattgctt gaaaataaaa ttttctgcat cgtcgatttc agcgatacta
     6661 ataatctgta aaatcaattc attcagtgat aggtcattga gaacaaaatt tttataaaca
     6721 acttcgaaat cttttcttaa cagctccatg ttctcattgg tataatttct actgttgaac
     6781 aaagaaaaaa tataatagac atcttcttct tgtaagtcta gaattccttt ttgctcttcc
     6841 aatccttgac agactaattg aaataacggc ttcgtttctg cgcttttctt atcttcttct
     6901 ttcagtccaa ggggaaatgc ctttcttccg attgcgatct ctattcctcg tatgataaag
     6961 gacttttcat cttccgaata tcttctttta aaaaaatgag tctctacata atcaatcaac
     7021 tcgttacaag cttcttctac atacggattt ttattttcat agccttccca attgacataa
     7081 cgtactaaag ctagcaagat gttccgcgag tcaaattctg ggataatgat ttctttattt
     7141 ttcaaataat cattttcttt aaaaaaatcc aatacgattt ttttgattgt atatactttg
     7201 ctcaaagaaa taaattcaag atcagccagt tctgtactcg tgaatatacc attaaaataa
     7261 taacttaaaa actttaaaaa ataagattga ccgtacagaa actgtgtgag ctcagaaaga
     7321 gcaataccat gtttgaatac gagtttatac ttatgcttct ctcttacttg ttcttttata
     7381 caatattcta gacactcggc tagactttct agatcgtgaa ggatcgttgg tgtagtcacc
     7441 cttagagaaa tagctgtttg ttcgatgtct atttcttgga attcaaataa ttgttcacac
     7501 agatacactt ttctaaatat atttcgctcg atgtaatttt ccagcattcc tgatacacgc
     7561 ctccagtttt tcttatgatt ttatttaatc atatctgtaa atcgtatttt tgtttccttt
     7621 ttatttagaa aagccctttc aaaaaccaat aaaaaaagaa actgggacaa aagtcaaaca
     7681 agctcacaat ttcagcctca ttgtaggtag ctttgagccg tttggacttt taccccagcc
     7741 tctttcaaga atggttattc aaagatgtca gcgtctagtt ctttgactac atctttcaac
     7801 aattggatac cagctgcgct gttaccaaat ggatctagtg ccgggctgaa gacacctatg
     7861 ccgtaacgat ttggcacagc tgccatcaac ccgccgccta caccgctttt tgcaggtaca
     7921 ccaacatgga cggaaaactc tcctgattca tcatacaaac cagcagttgt cataattgat
     7981 ttgacgattg tagcactttc ttcagtaatg atttgtttgc cattccaagg agcaattcct
     8041 ttatttgcca gcacagcagc taattttgct atgcctgtag cggtgacatt gagggagcat
     8101 tgtctgaaat aagcatcgag tatctccggt acgtctcctt cgatcatttg attacctttc
     8161 atatagtaag caagagagcg attgatatca cctgttcttg attcagaatg atagatttct
     8221 tcattcaatg tgatattagg atcatcacag atctctttca taaatgacaa gattcgctca
     8281 aatttttcat ctgcatcttt accggcaatc aacgaggttg ttgcaatcgc tcctgcatta
     8341 acaaaaggat tcattggatg tttgcgatga ttgatttcca tattcatgat agaattgaag
     8401 gcaaaaccgg ttggttccgt gttgattgtt tgaaagactt tttctattcc gttgtctttg
     8461 attgctaata acaatacggg aacttttgac atgctttcga tggcaaagcg cacatcggcg
     8521 tctcctccct caatcagttg ttttgtatcc aaatcataaa tcgccatacc taattgtttg
     8581 ggatccactt cagctaatgc tggaatgtaa tccgccactt gtcctgtttg ataatagtgg
     8641 aaattttttc caatcaattg ttctaattct tttacttcca tttgaataac cagctttcat
     8701 tttttatttt tctgcatgct ggaatttatg acggcatgcg tagatcgtaa atggaataac
     8761 taagacgata agataagaaa caatcagaat cgtttcataa atcccatgct gtccagctgc
     8821 gatactagca ggtggaacaa atgagataca aaaagcaaaa agtgaagtca aaagacctaa
     8881 acaagcaacg attactttta caacttttcc gcctggaacc tgataggctc tttcaagact
     8941 gtcatcttta aaaaccagct tcaaatagcc cgcgaaaaac ataaagtaca acatcaggta
     9001 gattacaaca gtcaatgaca tcgctgcaag aaatgaaaga ttattccccc cgccgcttaa
     9061 tgtaaagacg gctgcccaga ttgttgcaac gatcccattt gcgatcatca aatgagcagg
     9121 aacaccgtgt gtgttttctt ttgcaaaata ttcaggaagt aatccttctt ctgctgctac
     9181 gtgaagtgct tttgaaggag aggttaccca agaagcaatt tctccgatga cacctaaaca
     9241 aacaagaatc gcaagaattt tcgcaatcca tgcaagattt ggatcaatgt gtcttaatag
     9301 gaattctaac gattgaatca cccctgtatt aagagacaaa ccatgttgag gtactgtagt
     9361 agcgacggtc aatccgccaa aagtatctaa aatgattgcc agaataacca atacaaacat
     9421 tgctaatgga taatcctttt tagggttttc catttcattt gcatgactgg cagatgtttc
     9481 tacgcccata tatgctaaaa taaaggaaac aaaaacaacc agcgtaggca atttcgaaaa
     9541 atcaggaatc aatgttttca tagacagtat cgtttgtagt ggagcgcctg aagcgacata
     9601 atggatccct aagccaaaca agactaatgc tggcaacaag ataccagcta caaaaccgat
     9661 ccgagcaatc aatgaagtgt atttggttcc ttttaactgt gagagtaaaa tagcccagaa
     9721 aataatcaat aggattgcca atttcagata tttattgttt tgtatagcac caatacccgt
     9781 tgcataggat aatgcaccag ttaagaaata cagcatggtc aagtagccaa ctgttatctc
     9841 aaaccattgg aaaaagattg cggcaaaacc gaatcgtttt cccaatgtgc gactgaccca
     9901 agtatagaca ccgccttttt cccatccttt caccgttgcc atctctgctg cgcacaatgc
     9961 cacagggata aaccatagca aaccgcctaa taacaagaaa aatactaagc tgaagcctga
    10021 ggtcgcgaat gtgggatatt catataatga aacgaccatt gagatggtca tagccaaaaa
    10081 gccaaagaac gttaattttt ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc
    10141 tcttttctat ttgaatttgt ttcaattgag tttgttgcca aagaagaaaa agtccaatcc
    10201 ttcttcttgt tcttcttttg tagtagtgat cgttgtaaag tgcatcgccg attttaaaat
    10261 cactgttgtc agcacatagg catacacggc agtaatgatg acaccaatca cttgaatccc
    10321 taagaagtac cagctgcttg gattcgttag taaatggctg ttagatgcaa agatccctat
    10381 cagaatcgta cctgtgaatc cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc
    10441 ccattgtttc tttttacgaa aatcaacagc agcatgacag acgatacccg caatgatccc
    10501 aatcagcatg gcactttttg cttctacata accggcacaa ggcgtaatgg ctgccaatcc
    10561 agcaacggat cctgttagta cgtcgacaaa atcaaagcca tttcctttta cttttgcaat
    10621 gatcagccaa gtaatcatcg caaatgcaag agcgatgaat gttgaaccaa atgcattgac
    10681 tgcttgttca tctgctcgaa gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag
    10741 cagtcctgta ccgatagcag ctgccataag actgctatgc tgacttcttt ctcctaaagg
    10801 aatctttctt tgaccaagtg tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg
    10861 gatgactgct ccaccagcga aatctctaaa tcccatctga tccaaaaatc cgccacccca
    10921 tatccagtgg caaacaggga aataaatcag cagattccaa aaaataacaa gtataatata
    10981 gccttttaaa ttcaatctcc ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat
    11041 aaacatcagt tggtaaagaa agaacattaa aaatggaatc gttgcaccat gaaacatgtt
    11101 ggggaagctt gtaacatgtc tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc
    11161 gatatcccgt ccaaaggcca atccgaatcc accaaatacc cacataatcg ttgttatccc
    11221 aacggagaga aaagattgag acatgatcgt tagtatatta ttcttccgtg ctaatccgcc
    11281 gtaaaaaaaa gctagaccag gagtcatcag gcaaaccatt gctgtacata aaatcatgaa
    11341 tgctgtatct cctgtattga taggtaatgt attcattttt ttcgcctcct ttctacgatt
    11401 acgagtataa aagaaggtgt agttgttttt ttcttctgtt tttttgaatt aatacttgca
    11461 tttataaaag acagacaatt aataaaagct tgatgtgttg tgctcttttt cgtttttcac
    11521 acaaataaag acaaaaaata aacggtcttc tttttataga aaaccgttta ttttcgtctt
    11581 tttttatttt taaagatatt ttttcataag gaataaagaa tacttcatat aaaatatata
    11641 aaaaagaacc gcagcgagtg tcgctacggt tctcaaattt gttcttcatt tcaacataag
    11701 tttttcttca atttgcttat aatttacgtg caaagaatga aacgactaat actaaaatga
    11761 ttgcacctat caatgatgga atgatagcca ttcctgcaat tgttggtccc caagttccta
    11821 gtaaagcttg tccaattgct gaacctacta aaccagcaat gatgtttgcg atgatcccca
    11881 ttgatgatcc tttattcgtg attgctcctg caattgctcc aatgataccg ccgacgatta
    11941 atgcccaaat aaatcccatt ttaaattcct cctaactgac ttcttacttc ttattgtaca
    12001 cgtggttcgt tattttcttt gactttttgt gcacctttgc ctacagcaga ttttgcttta
    12061 tctgtttggc gtgaagcaaa ttgtcctgtg gattttgctg cttctgttac tttgtcttgt
    12121 actgtttctt gatctttttg gtattcttct tgtgttttga tgtctgcaac attcacattc
    12181 acttcgataa catctaaatg tgtcatattg tttacttcag tactgatcaa ttctttgatt
    12241 tggttgtaaa tatcttcgat gtctttaccg tattctacga tcacatctag atccacagct
    12301 acttgtttct tacctacttc tgtattgata cctgctgtta cgttatctgt gttgactaat
    12361 ttttcagcca tatttgagaa aaatccgcca tctaatgtca atagaccatc tacatctttc
    12421 aatgcataac cgatgatttt ttggatgact ttgtcttcat aagtcaattc accattcatc
    12481 atgcggtttt ctcctttttc atttgccaaa actgatccat ttgttgtatt catgtttttg
    12541 ttttccatct ttgtttcctc ctatgattta aaaaattgat caactattcc tgactgtttc
    12601 aaataaaaac cgattcctgc gccaattgct gtcatgatta tgatcaacaa tgtcttgaaa
    12661 aatccaatcg ttaaccataa aacagctagc agtagtccaa gacccccaaa gataataggg
    12721 agcttgtatg ctgaaaatag ttctttcatt atttggccct cctattccac tcgagagtgc
    12781 ttgtagtctc ttgtatcttc ttgttcttca taaccgctgt atgtgactgc cactttgacc
    12841 gtttcttttg ttccgagtac tttagttact tcttcttcga tatcttgcat caatacacct
    12901 gttttcccta ctaatgaaga agttcgtttc aagtctccgt tgacatggat atggattcga
    12961 tttttcgttg aacgtatccg tactttaggt gaatgaatga actcttcttc gtgtaaatgg
    13021 gaacgtacca acccttcgat cgcttttttg tcgattgtta gtttgccatc ttcccgtttc
    13081 ataacgaaag ttcctcttga ctttggatag aaaagaacga ctagcaagat gataatagca
    13141 agaacggcaa atactacagc tgcccagaaa atatattgtt gcatgtagta attcgttaaa
    13201 gtaaagaagc gaaatcgttc caattgttca ggcataatat acggcgcatt gatcaacgca
    13261 atcgctagaa atactgaaag tagcagtaaa ctcatgataa caccgattat ttttaacccc
    13321 ttattcattt tccacctcct ataaacttat ttttaccctg taaataactc taccgacaat
    13381 cacagtatag atagcgaaca gttagcatag catcagtaaa taaagcgcta ccaaacattg
    13441 ctggatcata acggcgtttt attgccagtc tgatactgaa ataacaattg cttacttatt
    13501 ctctatttac ttttgattgc tggctatact taaaggatat tattcaagat taaaaattgc
    13561 aaagattatg ctcagttatt attacaagat tctatttatt
//
LOCUS       DASHXG010000064        13521 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.066, whole genome shotgun sequence.
ACCESSION   DASHXG010000064 DASHXG010000000
VERSION     DASHXG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.066"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..117)
                     /locus_tag="U2R59_002321"
     CDS             complement(<1..117)
                     /locus_tag="U2R59_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEM8966668.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVG"
     gene            complement(110..601)
                     /gene="def"
                     /locus_tag="U2R59_002322"
     CDS             complement(110..601)
                     /gene="def"
                     /locus_tag="U2R59_002322"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEM8966669.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(616..3024)
                     /gene="priA"
                     /locus_tag="U2R59_002323"
     CDS             complement(616..3024)
                     /gene="priA"
                     /locus_tag="U2R59_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEM8966670.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(3277..3582)
                     /locus_tag="U2R59_002324"
     CDS             complement(3277..3582)
                     /locus_tag="U2R59_002324"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEM8966671.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(3587..4201)
                     /gene="gmk"
                     /locus_tag="U2R59_002325"
     CDS             complement(3587..4201)
                     /gene="gmk"
                     /locus_tag="U2R59_002325"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEM8966672.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(4688..4972)
                     /locus_tag="U2R59_002326"
     CDS             complement(4688..4972)
                     /locus_tag="U2R59_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966673.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(4990..5880)
                     /locus_tag="U2R59_002327"
     CDS             complement(4990..5880)
                     /locus_tag="U2R59_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HEM8966674.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(5900..6118)
                     /locus_tag="U2R59_002328"
     CDS             complement(5900..6118)
                     /locus_tag="U2R59_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEM8966675.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(6088..7788)
                     /locus_tag="U2R59_002329"
     CDS             complement(6088..7788)
                     /locus_tag="U2R59_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HEM8966676.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSLLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            8055..8828
                     /locus_tag="U2R59_002330"
     CDS             8055..8828
                     /locus_tag="U2R59_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966677.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(8909..9478)
                     /gene="thiT"
                     /locus_tag="U2R59_002331"
     CDS             complement(8909..9478)
                     /gene="thiT"
                     /locus_tag="U2R59_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEM8966678.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(9544..9646)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(9652..10623)
                     /locus_tag="U2R59_002332"
     CDS             complement(9652..10623)
                     /locus_tag="U2R59_002332"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEM8966679.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(10717..12090)
                     /gene="glmU"
                     /locus_tag="U2R59_002333"
     CDS             complement(10717..12090)
                     /gene="glmU"
                     /locus_tag="U2R59_002333"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEM8966680.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(12593..13411)
                     /gene="purR"
                     /locus_tag="U2R59_002334"
     CDS             complement(12593..13411)
                     /gene="purR"
                     /locus_tag="U2R59_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEM8966681.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
BASE COUNT         3716 a         2881 c         2359 g         4565 t
ORIGIN      
        1 cccaactgga cggtcgggct gtgttaccac tgcctggatc tcgtaacctg attctatcag
       61 cccttcaaga atcggcacag aaaaagcagg tgtgcccata aatactagct tagtcatcaa
      121 gatgttcctc catatattct tcaagttctt cttccgggat ctgctgtatc attttctcaa
      181 tgaacaagat accgtctaag tgatcgattt catgctggaa ggcacgggct aaatagccaa
      241 aagccgtcac ttctatctct tctccgtctc gatcataata acgcacggtc acttcatctg
      301 ctcgcttgac cgttccatag acatgcggaa tactgagaca accttctacg tcaaggcttt
      361 caccttttgc ttcgatgatt tctgggttaa tcagttcaaa tttctcgcct tcatctactt
      421 cgatcacagc aattctcttg ttttgtccta cttgaggagc agcgatccct attccgtcat
      481 tcgcaatcat tgtctcatat aaattgtcta ataaagcgat tgtctcgtcc gtgattacat
      541 cgattggctg agcagttctt tttaatttat cattagggtg gatcaatata ggatagcgca
      601 taatttggcc ctttcttaaa taaagtttaa tggttcgttg tcaattgcca caaaaagacc
      661 ttgtcgctgt tctttctggc ttccattcaa aatttcatcc aaaacatgag gaagattcgg
      721 ttcatgttta tatttgatga ttagttgata ataatatcgg tttttcactc tcaaaatcat
      781 gctgggcgtt ggccctaata gcaagctttg agggcttaac acttctttta gctgattggc
      841 aatctgaaag attttctttg ccgctacttg ttcttcagga tggctggcgg ttattttcac
      901 agtaaagtaa taaggaggat agcctccacg atgccgtaca tgcatttcct gctgataaaa
      961 ctgctcataa ttttgttttt tagccaattc tatggcgtaa tgttgaggat tgaatgtttg
     1021 gatcacgact tcgcctgctt tttccgctcg ccctgctcgt cctgaaactt gggtaagcaa
     1081 ttggaatgta tgctcactag aacgaaaatc cggtaaattc agggaggtat cagcattcaa
     1141 caccccaact aatgtcactt ctggaaagtc caaaccttta gcaatcattt gtgtccctaa
     1201 taatatatct gcttcttttg caccgaattt ttgtaaaatc tgttcgtgtg ccccttttct
     1261 tcgagtggta tctacatcca tacgcaaaat cctagcttgc ggataaagtt ctcggagttc
     1321 ctcttctact ttttgagtac ctgttccata gtagcggatt ttattgccgc cacaattagg
     1381 acagcgattg ggaataggtt cttcatgtcc gcaataatgg cagcgcattg aacgtgtatc
     1441 catatgcagt gtaagagaga tatcgcaatt aggacatgga agaacaaatc cacagtccct
     1501 acacatcaca aaagacgaat atcctcgacg attgagcagt aggacagttt gttctttttt
     1561 gtctaatcga ttttgtattt tttcctgcaa attagcagaa aaagtagagg tccgatgatt
     1621 ctgaaactct tcacgcatat ctacgatctc aatagctgga agctgtgcag ctgctttggc
     1681 tcggtggttt aactgcaata actgataaac gcctttttga gctcgtgctc ttgattctaa
     1741 agagggcgtc gcgcttccta gaactattgg gcaatgatga tatttactgc gccaaattgc
     1801 tagatctctc gcatgataac gcggtgtctc atcttgtttg taacttgatt catgttcttc
     1861 atcgataatg atcagcccga tatttttcag cggggcaaaa atagcagatc gtgcgcctac
     1921 tactacttgc gcttcttccc gctcaatctt gcgccattca tcatattttt caccttggga
     1981 aagtccgcta tgtaagaccg caactgattc tccgaagcgt cctttgaatc gctcgaccat
     2041 ttgcggagtc aatgcgattt caggcactaa cataatagcc gttttatttt ctgacaaaac
     2101 atcagcgatt gcctgaagat atacttctgt tttcccgctg ccagtgattc cctccagcaa
     2161 aaagacctga tctttttgct gctgacctgc tgtgatgatt tgttcgacag catttttttg
     2221 ttctgcattc agttccaatg ccgtcgtttg gtcaaatact cggtctttat aagggtcgcg
     2281 ataacgttct gattctataa actccagcca gcccttttct tttccttgat tcaagacagc
     2341 agtactgatt cctttatttt tgaaataagc aattggttct tcttggctca gttcagataa
     2401 acacaaaaga agttcttttt gtttcttggc attttgccgt aattttgccc attcttcttc
     2461 gatttgcttt tcagttaaca aagaacggac caaacgaatc gtttttactt tatttcgtgt
     2521 atggacttca tatttgatat ctactaattg ctcttggcgc cagcgaatca attgagaaag
     2581 gctgccttct tcttctgctt ccttccagga aatcacttct cgctgatcaa acaatacctg
     2641 aacttctggt gtgtctgcca aaggatagat caatttatca tattctgctt tcatcacact
     2701 cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa gtaatttttt tcatataatc
     2761 agctaatgaa agtaattctt cattgaccac cggagcaagg tctagcaaac gaataactgc
     2821 cttcaaagat ggattagctg attcttctga tttttggata gccataacaa atccttggac
     2881 atgacgattg ccattaccaa aagggacttc tactcgcatc ccgacttgca aagctgtttc
     2941 catttcagag ggaaccaaat aagtgaatgg ctgatcggtc tgcatagtag gtacgtccac
     3001 aatgacttca gctgttaatg tcatggttcg tttcctcctt tttttgtctt ttcttatcaa
     3061 gcgacaaaaa gttccttgcc tattttacta gagatcgatg gatttgtctt atcttctgcc
     3121 aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag aactgtgtca aaaagttcag
     3181 acacagcctt ttctaccaga caataagtgg cgaatgtttg aaaaggaaac agctgggttt
     3241 gcttttcttt ttagatgttc gctctatttt tctttattac attttttgct cttcacggat
     3301 acgtgattcc aattcgtgtt gttcacgctc tttttgtgct tgacgttcct cttcttccat
     3361 cttcaaacgt tcacgtttta attcaggatg tggatcattg actacatttc ctgcatcgat
     3421 ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa gaatctagag taggctgtgc
     3481 acttgcatcc aattcatgcg cgcgtttact tgctaaaatc actagagaat attttgaatt
     3541 tacacgatct aatagtgagt caattgaagg ttttaacatc ataagactac atctccttta
     3601 acattttaat atatttaccg attacgcgat ctactcgaaa atgttcactg gcaataatgt
     3661 ttttgattcg ttcaactgct agcggcactt catcatttac aacagcatag tcgtaaagag
     3721 ccatcatttc gatttcttct tttgcaactt tcattcgttt ttcgattact tcatctgcat
     3781 ctgttcctcg gcctacgatc cgtgatttta attccgctaa atctggcgga gtcaaaaaga
     3841 tgaatacacc atcgggcact ttttctttga cttgttttgc tccttggact tcaatctcca
     3901 agaaaacatc ttttccttca tccaatgtct tgttgacata tgacaaagga gttccataat
     3961 aattcccgac atattctgcg tattccagca tctctccagc ttcgatcatt gattcaaact
     4021 cttctttgct tcggaagaaa taatcaacgc cttcgacctc cccttcacgc attttacggg
     4081 tagtcattga gatcgaatac tgaaaatcat tatcctcact ctcaaaaatt gcttttcgta
     4141 ctgtgccttt tcctacaccg gatggaccag acaacacgat taataatcca cgctctgaca
     4201 tgacgacgtc ctttcaacta gtctttttgt acttatcgtt tattttgcac tttttttctg
     4261 caactttcaa ggttatcttt aattatagct agaaattggt aaaaaagcta ccctgtacca
     4321 agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca taaacagctt
     4381 ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc aagcttttga acgccgtgta
     4441 taagaggtcg tgaagaagcc gattagtttc gagtatgaag aaaaattttg tgaaaatagt
     4501 ttctcacatt tttgcataaa tttggcttaa taccgagaaa atggtttttg aacatcactt
     4561 attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca acctttaaat gtattcctag
     4621 agcaaagaag ctaagcgaag aaatccaatt ctgtttattt attgtatttc tttgttcagc
     4681 atccttgcta aaagcccata ttggacaaag tattcactac acccatgatc tcatcttttc
     4741 gagaacgtgc tttttctgtc ggatcttcta cctcttctgt gtcaattcga acaataaatt
     4801 tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat aaacagttcg ttctcattat
     4861 agtctgcaca ggcatctttc catacgtcaa agccgttttt ttcagaaggg atatcccgtt
     4921 taaccacagt ttttccactt aattcgtgga acgttacgtc ataatatttc attatctcta
     4981 cctctttcgt cattcaatat tttgtacttg ttctctgatt ttttctaaga tcgtcttaga
     5041 ctggacgact tgatttttaa tttcgattgc atttgatttg gaaccgatcg tgttgatttc
     5101 ccgattcatt tcttggatca ggaaatctaa ttcccgacct acaggacatt gtgcttcgat
     5161 aagttcatct agtttttgta catggatcgc cagacgatcc agttcctcgt gaatatctcc
     5221 gcgttccaac aagatggcta gctccgtcaa caaccgttgc tcatcgactt tcgctccaag
     5281 aaattcctcc agcttttttt gataccttat ttgaaattcc ttttcataga tttctacaaa
     5341 actatcgagt ttttttagta cttctttgaa ttcttcagta ttctttttca acactaaagc
     5401 taaagcttga ccttcttttt ctcgactcgc ctcaatagaa tcaagtgcgc ttttcaatgt
     5461 atctagagct aactgtgcca attcttccat gctctcttcc ggtttttctt ctaccgttac
     5521 gaagttttcg tccagcacga agcgttccgc catccgacta attgacactt gattttgact
     5581 accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata agtgaatcaa tcaattccca
     5641 gttgatgacg atctgttttt cgtttttgcc aatataagct agattcacaa atacttcgat
     5701 tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa tcgttttcaa caaagttcag
     5761 gattttagga cttcgtattt gaacatctag aaaacgctgg ttgacacttt ttatttcaat
     5821 atctaactga tacgcttttg tttcgcggat ggctttgcca aaaccagtca tacttttcat
     5881 tcgacagggt ccttcctcat tacatatttt ctattgcttt ttgcagttgt tcaaactctt
     5941 cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc tggcgcccaa tctcgaagat
     6001 cgaattttgg cgggcgacca ttccagctga ctaggttcag ttctttacgc caccccttgt
     6061 tgttttctga caatatagcg atttcttcta cgatttcata tgaaaattct tgtgccatgg
     6121 ttgttcctcc ttgagataat ataaatatag gatcagtaat gtgtcaactg gttgcttaag
     6181 caattcatgc tgcaaacgat ccttgcgttt tccttgtagc agataatcaa aataaacagt
     6241 tttcgtgcgc tcattttgta ttttttgctg gtattttcga taccttcgcc attcttcagt
     6301 acttaattga ccaatttgtg ccaataaatc atccggcata ctttttatat cttgttggca
     6361 gatcatttga atcatcatgt ctacttgata gatttcattg ggcagtaaaa aatgtttttt
     6421 tgctaaaagt tctagcatcg ccaatccgca tgtctctggt acgaccctgt tcttatataa
     6481 attacgcagt ttttgccaaa attttatgct tttgaaaaaa gataattcta actgaatttc
     6541 ttttgttaag taagacaaaa atcctcgcca gtatgttctt gcaggtttaa cagaatgaaa
     6601 tgtataccag ttcccatagt aatagcctaa tcgttttttc atttccagat agcctaattg
     6661 taaatttaat tggttccttt ggctatcaaa aagcagtaag ctgcctagtg tccacaatgt
     6721 ttgacatttc caatggataa aaatgtctgg catacgaatt tttttcgctg ggcctggccc
     6781 ttgcacatct acgacaaatg cctctgttgc tcctttgtta atcgcaatat caataggtat
     6841 tttgttgcga tacccaccgt ctgcatattt attttttccg atctttcgat aagccatagc
     6901 gggataaaat gaagcagagg cgagtatcca atctggtatt tcttctgttt ttgtctgttg
     6961 gatatcagtc actacttccg ctagttctgg cagtttagta gacaccgtat ataaacgtat
     7021 tttgggatta tgtttgagta aggacaaatc caaattgtct ttgaccatct tttccaatgg
     7081 agcagaagaa accccgcctt caattagtgc tgttttcgtc atttggcgtc tttctcgata
     7141 gaagcgttca cgaaggtctt caactgcagc catttctggt aacgcaagca cttgtcttgt
     7201 cgacagcttt ttccataaat tcacagcttt tttcatatct ccttgtaaaa tcaatgcgcc
     7261 gttcaacgca cctaccgagg tacctgtgat aatctcaaag ttgatatcat gttccttcag
     7321 cgcctgccac acaccaatct gataagcacc gtgcgctcct cctccaccta aaacaagtgc
     7381 tgtatgatag accagctttt tatttaattg tgtggttcct tgatagccgt ttttatgaaa
     7441 aatacgcaac cattcttctg atagaggaga ttgaaataaa aaacaacagt tttctttaat
     7501 aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt ttccattcaa aagtttcacc
     7561 ttcaatcaac agattattaa aaataacatc tcctctactt ttagcaatag taaaatagac
     7621 ggtatatttt ttcgatactg ctttaaaagc acattgcttt tttgcagaac gccaaaaagc
     7681 gtctctactt tcttgatgac tttgaaaaaa tggaaggggt tgttttgctt gctggatagg
     7741 cgaatacagc gacattttct gtgaaaagta aacttttttt atctccatcg cgctctcctt
     7801 tttcttcaag tataccagta cgtcataaaa aggtcatgag tctcgtattc gactttgtag
     7861 attccataag aaaacaattc ataaaacctc ctttaaataa aaaaatacaa aaatcacaaa
     7921 aattaattga aaatgagagt gttttcaatg aaaacgtgat tttgtaatgg aattttaaaa
     7981 taaaagaaac aagctttttt aatgcaaatg ttgtaaaata aaagagatta agaggaaata
     8041 agaggaggaa catgatgact gagtcagttt atgtacatat tgataccaca agtaatgctg
     8101 ttttaacaaa agggctgact gctactgact ttgcaaacag tatcgtgcat tttcctcaaa
     8161 acttgctctt gcttgatcca tctgcttctg ctggagaata tgaatcccat acagggctga
     8221 aagtaatccg tggtacagaa aatattcagc gtttcttttc ctcttctcgt aacaggcgtg
     8281 gattcgatga attgaagtgg atcgacttta ctgatttaac gatgctgaaa gaattgacac
     8341 ctttagaaat ttcagaatta ttatattttg gtcatatgaa aacacatctt cattcgccgt
     8401 ttttttataa actacagaat aattttgtat acttcgatct taatgatcag ctgaatcgga
     8461 tttattatcg ctatttagat gaattttata ggatttttgc tagtaaatta agttcgatct
     8521 tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa
     8581 tcagtgtgga attattgaaa gaaatgcgta atttgatgca ggaagggatc attttttctt
     8641 ttgatcaagt tggtttgatc gatggtaaat atcgtatccc aatctatgtg attgaagatt
     8701 atatttggaa attaaaaggc acccggtatc gagaagagga aatcatcgct actttaatct
     8761 actctgtcac cgatcgacac tggcaattgg tagaagatgc cgatctttct tatctgccat
     8821 tgaagtagat ctatttctta tcaaaaaata aaaaggaaac aagaaactag gacatgattc
     8881 tgtctcaagt ttcttgcttc ttttttattt acagctcctg tcgtttatct ggcacaaaaa
     8941 tcgaaggagt cgtttgttgg atccctaata aaacgatgat cgttacaata gctgtactca
     9001 acccgctggc accattcatt acgaaagaaa agagccaagg attcatcccc catagtgcat
     9061 acgctcccca gaaaaccact cctgcaataa aatgccaaaa atatctggaa agtgcgccaa
     9121 tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt attatcgtct acatagcctt
     9181 tttggacatt tgaagccatg agccctgctg cgcctgcaaa agtataggca atcgggtact
     9241 caatcaacac ttgaacgaca cttaaataat aaacttgtcc caacggaaaa tgtaggatgc
     9301 cccaaatgaa acctgccagc atccctgcct ttgtccctct tcttaacgca aaaagagtca
     9361 atggaatctg ccctaatgaa atagaaaaac tgctgccgat ctggatcgga atcaacgaca
     9421 acaccatcgc taacgctgca acaatcgttc cttctaccca aactctattt tttcccataa
     9481 aaaaacttcc tcctttgaat aaaaaagtca caaaggagga agcagctttc gaaaatagtc
     9541 aaacagctgt ttattcacaa ttcctacgct cgcataaccg atacaggtac gaagggttta
     9601 gaaatagatt caatctcagc ccaattggac tcccctttgt gagtttattt attatttatt
     9661 ttttgtttca aacaatggac taactggttt gttttcatgg atacgtttga ttgcatctcc
     9721 cattagtccg ccaacactta cttcatcgat tttgtcgatt ttacgatctt ctggaagata
     9781 gatcgagtct gtaacaacta gacgctcgat agctgaatct tctattcttt gtaaagcagg
     9841 gccggataat actggatgtg tacatgaagc atacacacta gttgcaccag cttctttcaa
     9901 agcattggca gccaatgtga tcgtacctgc tgtatcgatc atatcatcga tcagtacaca
     9961 agttttgcct ttgacttgtc caatgatatt cattacttct gcaacatttg cttttggacg
    10021 gcgtttgtct atgatcgcaa tcggagattt caaaaattcc gctaatttac gtgcccgtgt
    10081 gacaccacca tggtctggtg aaacaacgac aacatcatcg cctttgattc ctttttctaa
    10141 gaaataattg gcaataagtg gcgcacccat caaatgatcg actggaatat caaagaaacc
    10201 ttggatttgg actgcatgaa ggtccaaagt cagcattctt gttgcaccag ctttttgaat
    10261 catgtttgct actaatttcg ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg
    10321 cgcatagcca taataaggca tgactacgtt gattgttttt gcacttgctc gtttcagtgc
    10381 gtcaatcatg atcagcaact ccatcaagtt atcattgact gggctgctcg ttgattgaat
    10441 aacatagaca tgcgatccac gaatactttc ttcaatgttt acttgaattt ctccatcact
    10501 aaattgagta acagatgatt ttcctaactc gacgccgact gctgctgcaa ttttctctgc
    10561 taatgggcga ttggaattta acgcaaaaat ttttaatctt gggtcaaagt aatgttttga
    10621 catggggacc tccactttct ttttcacaac tctagaattc tacctaataa atagtagtca
    10681 tattttttaa ataaatcaag tgattttgca aaagtcttag tttagataag ggagtttttt
    10741 tgcatatcct tctttattga cttgtcttgc tctcgcaatt gccagcgcat attctggaat
    10801 attgtctgta attgttgacc cggcagcaat cgaactgttt ttagctacct cgacaggtcc
    10861 gatgatattc gtgctagaac caataaagct gtggtcgccg acagtcgtat gatgtttgtt
    10921 ctttccatca tagttgacga agacaacacc acatccgaca ttgatttctt ctcccagcgt
    10981 agcatcacca acataagtca agtgaccgac tttagttcct ttgccgattt gagcattttt
    11041 cacttccaca aagtttccga tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg
    11101 tgcataaggt cccacatctg catgtttctt gacatggctg ctttcaatga ctgagttttc
    11161 aatgacgacg tgatcctcaa tcctactgtc tacgattttt gaatgtgacc cgatgacaca
    11221 atcagaacca atgactgtat ttccttggat ttgtacacct gcttcgatca atgtgtctgg
    11281 accgatttct acgcctgcat cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt
    11341 gaccatatgc atctggttaa ttcgctttct catgatctca tttgctttag ctaacgcgat
    11401 ccgatcattg actcccattg attcttcaaa atcatccgtt tgataagcag caactgtatg
    11461 gccttcttct tttaagattt cgatgatatc tgttagatag tattcacctt gagcattgtt
    11521 tgttccaact ttgcttaacg catcgaacaa agcttcgttg tcaaaacagt aagttcctgt
    11581 attgatttct tgtacaagag cttcttctgg tgttgcatct ttttgttcca cgattttttc
    11641 tacgatccca atatggtcac ggatgattcg tccatatcct gttgggtttt ctgcttgtgc
    11701 cgtcaagatc gttgcacttg cattttttcc ttggtgatat tcaaaaagat tgttcagcgt
    11761 ttcagtagtc aataatggtg tatcgccact gataactaac gttgttcctt tttttccttc
    11821 caagaaagaa gcagcttgca aaacagcatg tcctgttccc aattgttctg cttgtaacgc
    11881 atatttactg cgttctccta gttgtgcttt aacttgttct gctccgtgtc caacgatcgt
    11941 aatcacttca tctggtttcg tttcactgac ccgattaatg atatgttcta ccataggttt
    12001 accagaaacg ggatgtaaaa ctttatataa ttttgacttc atgcgggtac ctttccctgc
    12061 cgccaaaata attgcataac gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat
    12121 ttcagtttat cccagtatac ccattttttc aacaaaacaa gtgattttct tttatcccag
    12181 cgttttctgg ataaaaaaat agatagacca taacgggcct atctatttgg taaccggtgc
    12241 tctcctgcca actcctcggt cacaagtcac actactcata aaacatgaaa agctgttttt
    12301 tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt acaacctctt cattaaacgt
    12361 ttttcaatca gctgaccttc ggtattagct caataaacgg caaaatatga ggagcaattt
    12421 ttccgtttat tgagctaata ctcaggacag gacgctgatt tcacaacctc tagataaacg
    12481 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gaaaaaatgt ggaaagccat
    12541 tttcacaaaa tttttcttac tactcgaaac taagcggctt tttcacaacc tcttattctg
    12601 aaaaataatt tcctggcaca accgtaatat ttttcgtttg agtatctaca tctttgacat
    12661 aaagcagtga cgtataatca tcgatggcgc gatgaccgtt gaattttgat tcggcaaata
    12721 cagtgatgcc aacaagttct gattcgaatt cttcaatcaa gctcttcatt ccgttgactg
    12781 ttccgccgcc tttcatgaaa tcatccacta caaggacacg tgaaccacgt ttcaaacttc
    12841 tcttagacag ttccatcttt tcaattcttt cagaagatcc agacacatag ttgacactta
    12901 ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat aacgaatggc gcattcagat
    12961 aataggacac agcttgggca ataggtacgc cttttgtggc tacagtcatt acagcatcga
    13021 ttttttcacc aaggtattta gaagcaatga ttcttccaac ttgacgcagc agttcaggtt
    13081 ctcctaacaa atcagagaga taaacatatc ctcctggaag cagacggtct tgttctgata
    13141 gacgttctgc tagagattca atatattttt tcgcctcttc atatgaaatt tcagggatga
    13201 acaatacacc acctgcagca cccgggattg tttccaaggt tccataccct cgttctttaa
    13261 atgttttctt gatgattccc aaatcttcac tgatagaaga tttagcagat tcataacgtt
    13321 cggcaaagct tgttaaggaa atcaattcat gcgggtgatt caataaatac tgtgtcatgt
    13381 caactagacg ttcactgcga cgtactttca cctattccaa ctccttttaa gaaattttat
    13441 cgttttacat tatataagtt tttcttcaaa aattcgagca ttttatgaaa aaataagaaa
    13501 atagttcggt atttattaaa a
//
LOCUS       DASHXG010000065        13374 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.067, whole genome shotgun sequence.
ACCESSION   DASHXG010000065 DASHXG010000000
VERSION     DASHXG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.067"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            133..2922
                     /locus_tag="U2R59_002335"
     CDS             133..2922
                     /locus_tag="U2R59_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEM8966682.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            2969..3496
                     /locus_tag="U2R59_002336"
     CDS             2969..3496
                     /locus_tag="U2R59_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEM8966683.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3517..4707
                     /locus_tag="U2R59_002337"
     CDS             3517..4707
                     /locus_tag="U2R59_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8966684.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4747..6045
                     /gene="asnS"
                     /locus_tag="U2R59_002338"
     CDS             4747..6045
                     /gene="asnS"
                     /locus_tag="U2R59_002338"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEM8966685.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7221..7895
                     /locus_tag="U2R59_002339"
     CDS             7221..7895
                     /locus_tag="U2R59_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEM8966686.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            7892..8233
                     /locus_tag="U2R59_002340"
     CDS             7892..8233
                     /locus_tag="U2R59_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966687.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            8263..8622
                     /locus_tag="U2R59_002341"
     CDS             8263..8622
                     /locus_tag="U2R59_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEM8966688.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9147..11231
                     /gene="cadA"
                     /locus_tag="U2R59_002342"
     CDS             9147..11231
                     /gene="cadA"
                     /locus_tag="U2R59_002342"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEM8966689.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            11522..12988
                     /locus_tag="U2R59_002343"
     CDS             11522..12988
                     /locus_tag="U2R59_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8966690.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4423 a         2321 c         2891 g         3739 t
ORIGIN      
        1 aaaataaacg cccagacatt tgcgtgtctg ggcgtttttg tctattttct ttaaaaagcg
       61 atgagagtat ttttctgcac tttgtagtat aatttcaaaa gaacattaga ggcaggagaa
      121 gaggaagata ttttgaaacc aagaacttat gcagtcgttg atatcgaaac gactgggacg
      181 aatccaaaag aagatcggat catccaattt ggctgcgtca tgattgaatc aggtcggatc
      241 acttcacgtt tttcgatcga tattcatcca gggcggaaga tttcaaaaca aatccagcat
      301 ttaacaggga tcacgaatca acgcgtccaa aaagcgcctt atttcgaaga tgtcgcccaa
      361 acgatttaca atcttttggc agacaccata tttgtcgcgc ataatattta ttttgattat
      421 aattttttga accatgaact catgcgatgc ggacttccta gtttgaagat accaggcatc
      481 gatacagtag aacttgcaca aattttcttg ccgacggaac caagctttcg cttagctgat
      541 ttgtcagaaa gccttggatt tattcatgag aatcctcatc aggcagatag tgatgccgaa
      601 gtgacaggtc aacttctttt gctgatcgaa gaacggatga gaaaattgcc aatcatcacg
      661 ttagagcaga ttgcgcgatt aagtagacac acaggtatgg atacgagtcg tttcatttat
      721 catgtgattg aagaaatgaa agaaaaacca gagccacttg atccctcatt agaaatcgtc
      781 gatgggctag ctttgcagaa aaaagaagtg gaactattca catccgtcca ttatggcgag
      841 cggacatatc caagaaaaaa acaagcaaaa gaaaaaatgt ttggtaaaac actgatgtat
      901 cgaaaagaac agaacagact gatgaatgcg gtctacgacc atttcacaaa agatgaatca
      961 aaagatttga tgatcgaagc agctacagga atgggtaaaa caatcggtta tctgctgcca
     1021 ttgagttatt tggctacacc tgaaaaaccc gctgtcatca gtaccgtttc gctagttttg
     1081 cagcagcaga tcatagaaaa agacattcca ttgctgaatc aattgctaga tcagcccata
     1141 caacctgtaa ttatcaaaag ctatcgccac tatattgatt tgcagcgttt taaaggcaca
     1201 cttgtggaac cgccagaaca aaaacaatat gctttgtatc aaatggcggt cttagtttgg
     1261 ctgacgcaaa cgaagactgg tgatttggat gaattacatt taacaaattt gaaccattca
     1321 ttctttgcag atatcgcgca cagaggtatt ggatttttag caagaaatca gtcattttac
     1381 gaacaagact ttgttcgttt cttgcaaaag aaaatcaggc aaagtaattt tttgattgtc
     1441 aatcatgcgt ttttagtaca agaaacacag cgaaaagaac cattgcttcc agctagtcca
     1501 tttttgttga tcgatgaagt acatcatttg ccggaaatcg ctgaaaaagt aaatgacaaa
     1561 cgattaagta ttaactattt ccataaacaa atccagcaat tagaagaacc aaatcagctg
     1621 tttgaccgaa tacaaagcta tttaccgaaa gaacatgaag ccttacgctg gttatcgatt
     1681 tatcgagaag aactttctgc gctatgcgaa gcacagattt gtatggcaga aggattaatg
     1741 agtttagtga gcggcaagca acctaacgga cagtatccag aagaagtcat gatgacaaaa
     1801 gagatgttgg atcagctgcc actggaatct gggacagcca ttgatcacct gcagcttttt
     1861 tatcaggaga tccagcagct acagtcacaa atgcgtctga cttttgagat tatccaagaa
     1921 agctggacaa accagatgcg gatcgattta gcaagtttat atagcctatt tgatcaatta
     1981 gacaagcaat acttgctgat ggatcaatgg ctggaagact ggcgagatca tttgatccat
     2041 tggttcgttc ctgggaacac agcgcagcag atgatttttc atctccatga ttttcaagcg
     2101 gctatgttgc cgtcgactgt ttggtatcct cgatatgatc gtattcttta tattggagga
     2161 acgctgaaga tcggccctaa tcgacactat ctctctaaga ggcttggcat tgaagcagca
     2221 cctcttaaag tgattgcctc tccttatgat tatgagaaac aggcaaggat ctatgtgcca
     2281 aaagaggcac ctgccgtcca tcaagtcagc aatcaagcat atatcgatta tttagagaca
     2341 gcacttacag gtctgatcga acaagaagat cggccaatac ttgtgttatt cacttctcat
     2401 gatgttttgc agaaggtcta tcagaaaatg catctgtcta tgctagaaaa aggacgagaa
     2461 atactagctc aagggtttgg tggaagccgg gagaagcttt tgaaacgctt cattttgtca
     2521 gaaaaaagcg tattgtttgg cgctgacagc ttttgggaag gtgtagattt gcctggagat
     2581 gctttgcaga tcgttgtagt cacacgttta cccttcgata atccgcttcg cccgatggtc
     2641 aaagctagga acgcttattt agaatcagag gggatcaatc ctttttacca ggaatccgta
     2701 cctaaagcag ctttgaagtt acgccaagca ttaggtcgct tgataaggac ggagacagat
     2761 cgtggcgtat tgcttatttt ggatcgaaga ctagtcactg caaaatatgg cgcacggatc
     2821 atccatgcat taccgaaaaa agtaccgatc aaagagctag ctatggagga aatctatcag
     2881 gatatccatg aattcttaaa gaaaaatgaa gaaggaagtt agaggagctg tcttttttca
     2941 taattaaaat ctgctataat gaaaaggaat gaagataaag gagcgacgac ccttgaagaa
     3001 aaaacagaca aaggaaaaaa cgattaatcg cgtgttactt ggcttgatcg tatttttatt
     3061 agcggtcatc gtgatcagct cgatttttta cttgcgttcc agtcgtccgg cggtgcaggc
     3121 gaagaaagaa gcagtagaaa tcgcaaagaa atatgcaaat cttgaggaaa ccgatcattt
     3181 ttattggttt actcgaaaga agacatactt ttcactgaca ggtacaaatg ataaaggaaa
     3241 agaaatcgcc gttatcattc ctaaatctgg tgaaaaagta aaagtattgg atcaaacaaa
     3301 gggactgact gaaaacgaag caaaacagac aattgctgcg gcccatcctg aaatccaaat
     3361 cgaaaaagct gctttaggga tgtatgatga tcagcctgtg tgggaagtag taggaaaaga
     3421 aacaaatggg aaactgaatt attacctgat tggctttgaa tctggagatg aagtcaagac
     3481 aatcaaggga atttaaaagg taaaggaatg aatgggatgg agttatcaaa aagaacaaaa
     3541 cgattagaac cgtctgtcac tttggcagct gcggcaaagg ccaaggcatt aaaagcaaaa
     3601 ggcagagatg tgctgagttt gactgtggga gaaccggatt ttgcgacacc agaaaacatc
     3661 caagaagcag caatcgaagc aatccgcaat gggaaagcta gctattatac accaacagca
     3721 ggaatcccag agcttcgaca ggcaatcgtt gattatctga agaaaaacta tggacttgtc
     3781 tatgaacctt cacaaacagt cgtaacagac ggagcgaaat ttgctttgta tacccttttc
     3841 caaacgatcc ttgacccgca agatgaagtc atcattcctg tgccttactg ggtcagttac
     3901 ggtgagcaag taaaactggc agaaggactt cctgtctttg tgaaagggga agaatccaat
     3961 agctggaaag ttactgttga acagctagaa caagcacgtt cagaaaaaac aaaagccgta
     4021 atcatcaatt ctccatcgaa tccgactgga atgatttata gcaagaatga actgcaggca
     4081 atcggtgaat gggcagtaaa aaatgatatt ttgatagttg ctgatgatat ttatggccgt
     4141 ttagtttata atggcaatga gtttactcca attgcaacga tttcagaagc aatcaaaaat
     4201 cagaccatca tcatcaacgg cgtgtctaaa acatatgcga tgacaggctg gcgcattggt
     4261 tatgcggtgg gaaatcctgt gatcatcaat ggaatgatcg ctgttgcttc ccaatcaact
     4321 agcaatccga cagcagtcag tcaatatgca gctgttgaag cattgaaagg tgagcaagat
     4381 acagtagaag aaatgcggaa cgcctttgaa gaacgcctga atacgttata tccgcttgtg
     4441 gcagaactgc cgggtgtttc tcttgaaaag ccgcaaggag ctttctatct ttttcctaat
     4501 gtaaaagaaa cgctacgcat gtgtaagtat gaaaatgtca cacaatgggt agaagatctt
     4561 ttagaagaaa caggggtagc gcttgtgact ggcgaaggct ttggggcacc agaaaatgtc
     4621 cgcatgagtt atgccactga tcgcgctacg ttagaagaag cggtacgcag aatcaagcaa
     4681 tttattgaga gtaaaagtca aaattaatcc tgaagaaatt caaggaatat aaaaggagag
     4741 tcatacgtgg aacaaattca aatcatcgat tcgaaaaacc atgtgggaga aacagtaaca
     4801 atcggcgctt gggtcgcaaa taagcgatca agcggaaaaa tcgcattttt acaattaaga
     4861 gacggaacag cctttttcca aggtgtagtt gtaaaaagcg aagtgtcgga agaagttttc
     4921 caaacagcta aaaatctaca ccaagaaaca tccgtgttag taactggaga aatccgtgaa
     4981 gacagtcgtt caaaatttgg ttatgaaatc ggaattacaa atgtggaagt ggtaagcgag
     5041 agccacgatt atccgatcac accaaaagaa cacggaacag atttcttgat ggatcatcgt
     5101 catttatggc tgcgttcttc aagacaacat gcgattatgc agatcagaaa tgaaatcatt
     5161 cgtgcaacgt atgaattctt taatcaacat cattttgtca aaatcgatcc gccgatcttg
     5221 actggttctg caccagaagg cactacggat ctattcgaaa caaattactt tgatcaaaaa
     5281 gcttatttat ctcaaagtgg ccaattatac atggaagctg ctgctatggc tttcggaaaa
     5341 gtcttttcat tcggtccgac tttccgtgct gaaaaatcaa aaacacgacg tcatttgatc
     5401 gaattctgga tgatcgaacc agaaatggct ttcactcatc aagaagaaag tttagaagta
     5461 caggaacaat atgtagcatt cttagtacaa aatgttttag atcattgcga atatgcatta
     5521 gatgtactag gacgagacaa agaagtctta aaaacttata caaaattgcc attccctcgt
     5581 attacttacg atgatgcaat cgaattactg aagaaaaatg gatttgatga catcgaatgg
     5641 ggcgaagact ttggttcacc tcatgaaacg ttcattgcga attcattcga acagcctgtc
     5701 tttatcctaa actatccaaa agccatcaag ccattctaca tgaaaccaca tccaacaaga
     5761 gaagacgtgg taatttgtgc agatatgatc gcaccagaag gttacggtga aattattggc
     5821 ggaagcgaac gggcaacaga ctatgatttc ttgctagaac aaatccgtaa tcacggtttg
     5881 gatgaaaaag aatattcatg gtatcttgat ctacgtaaat acggttctgt tccgcactct
     5941 ggttttggtc taggccttga acgaacagtc acttggattg ctggtatcga ccatgtacgt
     6001 gaagctattc cattcccacg tttgttgaac cgaatttatc cataagaggt gatgaaaaag
     6061 ctgttctgca tcaagtaatt agaacagcca agcaaaaaca gctgttcatg tttttgaatt
     6121 ggcgggactt attaccgcag atgtaagctt ttgaataccg tttagtggag aggttgtgaa
     6181 aaagctgttt agtttcgagt attaagaaaa attttgtgga aatggctttc cacatttttg
     6241 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttaagg aagaggttgt
     6301 gaaatcagtg ccttgacctg agtattagag aaacaaaacg gaaaaatagc ttctcatatt
     6361 ttaccgtttt tttagctaat atcgagggtc agctgattga acaccgttta tatcaagagg
     6421 ttgtgcgcct gccgttcagc tccgagtcac aaggagtaat ttcaaaaaac agtttttcat
     6481 gtttgatgac tattgtgact tgtgaccgag gagttggccg gagagcaacg tttatttaaa
     6541 aaaaagaact gcgaactctc gcagttcttt ttttaaaata cgggataaag gaagtttcca
     6601 gcagacaaga gaagaaagca aaagaaattg ctatttgatt cacaaggttc tataacgaaa
     6661 tcgcaatcaa tcaaacatat acaaagaagg ttattcaaat ggaaatctga tttgatgatg
     6721 cttctgctgt tgaaataaag cagcatctag tacctgaaaa caaactaata gtaacattcg
     6781 aagatggagt aggtccgtat tttcagcatg caatgatcca tatgtaagtt taattcatcc
     6841 ttgaaatcat cggaccagat aaagttatga ccaatctatc ccaagcaatc tagaagagat
     6901 attagtaaaa gaacatttac tggaagtctt agatgagcct ataaatatat gttctgatgg
     6961 cgtcatcagt ggtctgattg acggaagctt aggtgtgatc gatttctctg gaccaaacaa
     7021 cgaaggaatc aaggggaatc cggcacgtta agaaaaaaag tataaaaaac tagacacttg
     7081 atgagcgttc attcaattga ttgaagggac taggctggtg tcatttttta tacatatatt
     7141 ttctctttcg tcttgatagg gcttatggga taatataagg aagaaaatca tcgttttatt
     7201 caaaaaggag tttttgacaa atgaaaaaac gtatattatt tatcggtgac agcattacag
     7261 acgcaggaag agaccgagca gaagcaactg atctaggtaa aggttatcca cttttgattg
     7321 ccggaaaact aatctcccaa tatccaacga tgaaatttga atgcatgaac cgtgggatag
     7381 gaggagacaa aattgcagat ctgcaagtac gctggcaaga agattgttta gctttacaac
     7441 ctgactatgt atcgattttg atcggaatca atgatacctg gcataatact agcgatcagg
     7501 ctatattcgg aactgagaaa tctgcgcagc aatttgaatc cgtttatcga aaattactaa
     7561 atgaacttca aacagcggaa atctgcaaca tcatcttgat ggagccgttt gtacttccta
     7621 taaccgacga ccgtcatggc tggcgtaaag acttagaccc taaaatccaa attgttcgta
     7681 aacttgctaa ggaatatggc gcattgctgg ttcctttaga tggcatattc aatgctttag
     7741 ggattgctta tggtttttcg aaatatacaa gagaagatgg ggtccaccca acgattggcg
     7801 gacatgagat cattgcacaa agctggatag atgcaattgc cgcagtcgat ttttttagtg
     7861 gagataaaaa tgagcgaaag aaaagtgaga aatgatggaa atacggtggg cagtaaaaga
     7921 agatttacct caaatcaatc agctgattac tgatcatcca gaatcattcg taaaagcaaa
     7981 aacggcagct gacctaaatg ataagaataa actattgctc gttgctgtaa caaaagaaaa
     8041 acggattatc ggatttgcgc aagcggacgt gcaacagtca gaagaacggg tggatcagcg
     8101 accatcagga aaactaatcc aacacacatt agtaacaaaa gaaaatacgg aagaaatcca
     8161 aaaaaaattt gcagaatact tgatgctgga agctaaaaaa agaagaataa aatcaatttt
     8221 tgcccagttt taatcaaaaa cagtaataga aggagaaata caatgagttg tttaggaaat
     8281 gtcatctggt ttatattcgg cggactaatc ggtggtctta gctggttagc agcggggata
     8341 ctttggtgta tcacgatcat aggtatccca atcggtatgc aatgttttaa gatcgcctcc
     8401 ctttcttttg cgccttttgg caaagaagta atttatcacc agtctggcat gtcattgatc
     8461 gttaatatca tctggctgat cgtttcaggc ctaccaattg ctctcgcaca tgtcgtcagc
     8521 ggcatccttc tatgtatcac gatcataggg ataccttttg ccaagcaatc tttcaaactt
     8581 gctcgattgg cgttgatgcc attcggtgca gaaattgtat aaaaagagaa taataaaggt
     8641 tagaaaacgc atagagtcag gtgggataca tgtatttcac ctgactctat gtgttttcct
     8701 gtataagttc tcccatgtga cttttacgtc ttttatttat atgggattac tgtttatgga
     8761 aagttgaaat aattttcatt aaagaactct ttctatattt ttgaaagcgt agtggagctt
     8821 cgaatatctg ggaaggacat tttgcaggga ttgaaaaaag atattgtcct atcgaaaaat
     8881 taatgaattt agacaaattg ccagcaacag gcttcaaact tagttgctat cctgtcaaga
     8941 tcaagaaggc aagtgcgggt tggataagag caggggcaat gatcgaagag aaaaagaaag
     9001 aataagccaa aacatctgta tggaagaaat tttccgatgc agatgttttt cattttttct
     9061 ttcggatacc ttgacatatg aataaccatt catttataat tagttatgaa gagatgttca
     9121 tatgttgagg cgaggaggtc attaaaatga aaagttacag attagaaggt ttagattgtg
     9181 cgaactgtgc aatgaaaatc gaaaaaggag ttcagaagat caatggagtc aaggaagcaa
     9241 cggtaaactt cacttctgga aaactaacga ttgacgcaga ggaagatcat ttggctacga
     9301 ttgaacaaga aacaaaaaaa gtagtgaagg aattagaacc agatgtcaaa gtaacagaaa
     9361 tagataagga aaaagtatct gaacatggaa atgaaaaaga gagaaatacg ctgttccgga
     9421 ttttattttc ccttgcaggt atcgctttat tgctattatt tgattttaat gaaccaattc
     9481 gcttgatagg gtatttattg atttatctgc tgataggata tgatgtagtg aagaaggcag
     9541 tgatgaatat cgtcaaagga aaaatctttg atgagaattt tcttatgtct gttgctacga
     9601 ttggcgctat gttgatcggt gaatatccag aagccgtagc agtgatgcta ttttatcaaa
     9661 tcggcgagta tttccaagga ttggcagtca gtcattcaag aaaatcgatt cgcgaattga
     9721 tggcgatccg tccagaaaca gctcacgtgc agacgacgga aggattgatg accgtgaacc
     9781 ctgaagacgt gcagatcggt cagtttgtac ttgtgaagcc tggtgaacgt gtaccgttag
     9841 atggaacgat catcgaagga gaatcattag tcgatacgtc agcacttaca ggagaatcag
     9901 tccctaaatc tgtatatgtt ggtgaaacag tattaagcgg atttatcaat aaaaataaac
     9961 catttttagt tcaagtagaa aaatcttatg aaaattctac tatcagcaaa ttattagaat
    10021 tagtagaaaa tgccagcagt aaaaaagcac cagctgaaaa tttcattact aaattcgcgc
    10081 gctattacac accagtcgtt gtaggattgg ccgttttatt agctgtttta cctccacttg
    10141 ttgtttctgg agcggcgttt tctgaatgga tctatcgagc attgacattt ttagtgatct
    10201 catgtccatg tgcattagtg atttccgtgc cacttagttt ctttggcggt atcggaggcg
    10261 caagtaaaat cggtgtatta gtaaaaggtt caaattactt ggagttgctt gcgcaaaccg
    10321 agacagtggt attcgataaa accggcacat taacgaaagg tgacttttcg atccagacga
    10381 tcgatacaaa aatcgatcca aagaaattca tgcaatatat tgcgagtgca gaacagtttt
    10441 ctacacatcc gattgctcaa tctgttttag aaggctacgc aggtccgctt ttaccaacaa
    10501 ctaatatcca ggaatttgca ggtgaaggga tcttagctga agttgatggc aaacaagtat
    10561 tagcaggtaa tcacaaattg atggaaagat ttgaaatctc ttttccttta agtcaagaaa
    10621 tcggtacatt gctttatcta gcgatcgatc aaagttacag tggttatctt gttattgcag
    10681 ataccttgaa agaagatgcc gtagacgcat tggttcaatt aaaacaggct ggtgtgaaga
    10741 acacagtcat gttgacgggc gactcgaaaa aaattgctga tcatatcggg aagcaagtag
    10801 gcgtggacaa gatatatagc gaattgcttc ctgaagataa agtgcagcgg ttagaggaaa
    10861 tcttacaaag aaacaataaa aagaccgcat ttgtcggaga tggaatcaac gatgcaccgg
    10921 tgctagcaag agcagatgta ggaatcgcaa tgggtggatt gggaagcgat gctgcaattg
    10981 aagcagcaga tgtagtcatc atgaatgatc aaccatcgaa gattgcagaa gcaatccatt
    11041 tagcaaagaa aacattgaaa atcgtcaaac aaaacattgt ctttgctatt gggataaaaa
    11101 ttttggtact tgccttaggt gcttttggtt ttgcatcaat gggagatgca gtatttgcag
    11161 atgttggggt gacagtatta gctgttttga atgccatgcg aagcttgcat gtaaaaaaag
    11221 aggacgaatg aacgtcctct tttttttata tccttttctt aatgaaaaat gtaaagaaaa
    11281 tagataggat tataaaataa ctaatgtttt taattttgca gaaaattcaa aatagcttga
    11341 aattcaataa ggtcaatgaa ataaaagaaa ataacttatt tttttgatgg aaaaaatatg
    11401 aaaaaacgat gtgtattaaa taaaagaata cacacataaa ataacactgt cttgtaagtt
    11461 tgttaaaaat tgaatatgat tacatctgga taacaaattt ttatcataaa ggagagaacg
    11521 aatgaacaac aaacaattac gctggtttac tgttgcgtta attgcattta acatggtttg
    11581 gggcatgggg aatgtagtta ataactatgc tcagcaagga gtatcagttg tcacctcttg
    11641 gctattgatt ttggccattt attttattcc atacgcattg atcgttggac aattaggatc
    11701 agccttcaag gatagtaaag gaggcgtcag ttcatgggtc gaaaatacga catctaataa
    11761 acgactggca tactatgccg cttggactta ctgggtcgtc catattcctt atttggcaca
    11821 aaagcctcaa gcaattctga ttgctggtgg ttgggcagtc caaggaaatg gaaatatcgt
    11881 aaatacgatg tcagtacaaa tggtagcagt tatttcactt attatatttc ttgccttttt
    11941 atatttatca acaaaaggac tttctacttt gaaagtgatt ggcggactgg ccggaacagc
    12001 gatgttcgtc atgtcgatct tatttattct tttagctgta acggcaccgt tcatcaatcc
    12061 aacgatggaa tttgccacac cacatatgaa tcaagtgaaa acatatattc caacatttga
    12121 tttcagttat ttcacaaccg tttcgatgct agtatttgca gttggagggg cggaaaaaat
    12181 atccccttat gtcaactcta caagaaatcc tgcaaaggaa tttcctaaag ggatgatctt
    12241 cttagcagca atggtaggga tttgtgctgt attaggctca gtcgcaatgg gtatgctgtt
    12301 tgctagtgat aatattccta aagacttgat ggcaaatggg gcatacagtg cttttcaaat
    12361 tttaggtaat tactatggta tcggtaactc attgatgatc atttacgcat tgacaaacat
    12421 gattggacaa atctccgcat tagccttttc aattgatgca ccactaaaaa tcttgttagc
    12481 agatgcggat ccagaatttg taccaaactg gctacgtaaa cgtaatcgta aaggtacatt
    12541 ggtgaatggt tatcttctga caggtatact agtaggaatc attattttgt tgccgatttt
    12601 tggtatcaaa gatatgaatg aattagtaaa atggttgacg aacttgaact cagttgtcat
    12661 gccaatgcgt tacctatggg tgttcttggc atatatgatg ttgaataaag cttataagaa
    12721 attcaattct gaatataaat ttgttaaaaa tccaaaaatc ggttttatct ttggtgcttg
    12781 gtgctttgcc ttcactgcgt ttgcatgtat cctaggaatg gtgccaaaag tagattatac
    12841 tgctgatcct aaagcatggt ggttccaatt atttacgaat atcatcacac caatcgtctt
    12901 gatcttatta ggtatgatct tgccagcaat tgctcgtcga gacaaaaaca aagaaatcac
    12961 tgaaccagaa acagtggttc agccttaaaa tagaaatact tgttacaaga ggttgtgaca
    13021 gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc aaatttttgt
    13081 gaagtttcgg cttgtttttc gaagaagcta cttctggaac accgtgaatc agaggttgtg
    13141 aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagccc ctcatatttt
    13201 tcgtttggct gggcttatta ccgcagatgc aagctttgga acaccgttta aggaagaggt
    13261 tgtaaaatca gcgatttgac ctgagtatta gagaaacaaa cggaaaaata gctcctcata
    13321 ttttgccgct ttttgagcta atgctgaagg tcagctgatt gaacaccatt tatt
//
LOCUS       DASHXG010000066        13145 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.069, whole genome shotgun sequence.
ACCESSION   DASHXG010000066 DASHXG010000000
VERSION     DASHXG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.069"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(77..149)
                     /locus_tag="U2R59_002344"
     tRNA            complement(77..149)
                     /locus_tag="U2R59_002344"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="U2R59_002345"
     CDS             530..1099
                     /locus_tag="U2R59_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEM8966691.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="U2R59_002346"
     CDS             1086..1946
                     /locus_tag="U2R59_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEM8966692.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="U2R59_002347"
     CDS             2136..2840
                     /locus_tag="U2R59_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8966693.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="U2R59_002348"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="U2R59_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HEM8966694.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="U2R59_002349"
     CDS             4677..5993
                     /locus_tag="U2R59_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966695.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="U2R59_002350"
     CDS             5994..6863
                     /locus_tag="U2R59_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HEM8966696.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="U2R59_002351"
     CDS             6918..7727
                     /locus_tag="U2R59_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8966697.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="U2R59_002352"
     CDS             complement(7830..8459)
                     /locus_tag="U2R59_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HEM8966698.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="U2R59_002353"
     CDS             8629..9921
                     /locus_tag="U2R59_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8966699.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="U2R59_002354"
     CDS             complement(9997..10659)
                     /locus_tag="U2R59_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEM8966700.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="U2R59_002355"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="U2R59_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEM8966701.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="U2R59_002356"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="U2R59_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEM8966702.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2264 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccatt
//
LOCUS       DASHXG010000067        13072 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.070, whole genome shotgun sequence.
ACCESSION   DASHXG010000067 DASHXG010000000
VERSION     DASHXG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.070"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..192)
                     /locus_tag="U2R59_002357"
     CDS             complement(<1..192)
                     /locus_tag="U2R59_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8966703.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKN"
     gene            431..874
                     /locus_tag="U2R59_002358"
     CDS             431..874
                     /locus_tag="U2R59_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8966704.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(880..2064)
                     /locus_tag="U2R59_002359"
     CDS             complement(880..2064)
                     /locus_tag="U2R59_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HEM8966705.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2332..3030
                     /locus_tag="U2R59_002360"
     CDS             2332..3030
                     /locus_tag="U2R59_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEM8966706.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            3037..3714
                     /gene="nth"
                     /locus_tag="U2R59_002361"
     CDS             3037..3714
                     /gene="nth"
                     /locus_tag="U2R59_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEM8966707.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3840..4373)
                     /locus_tag="U2R59_002362"
     CDS             complement(3840..4373)
                     /locus_tag="U2R59_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966708.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4670..7051)
                     /locus_tag="U2R59_002363"
     CDS             complement(4670..7051)
                     /locus_tag="U2R59_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEM8966709.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(7041..7688)
                     /gene="recU"
                     /locus_tag="U2R59_002364"
     CDS             complement(7041..7688)
                     /gene="recU"
                     /locus_tag="U2R59_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEM8966710.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7752..8291
                     /locus_tag="U2R59_002365"
     CDS             7752..8291
                     /locus_tag="U2R59_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEM8966711.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8381..8800
                     /gene="gpsB"
                     /locus_tag="U2R59_002366"
     CDS             8381..8800
                     /gene="gpsB"
                     /locus_tag="U2R59_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEM8966712.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8822..9189
                     /gene="rnpB"
                     /locus_tag="U2R59_002367"
     ncRNA           8822..9189
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="U2R59_002367"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9398..10564
                     /locus_tag="U2R59_002368"
     CDS             9398..10564
                     /locus_tag="U2R59_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEM8966713.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10610..12106
                     /locus_tag="U2R59_002369"
     CDS             10610..12106
                     /locus_tag="U2R59_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HEM8966714.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            12187..12870
                     /locus_tag="U2R59_002370"
     CDS             12187..12870
                     /locus_tag="U2R59_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8966715.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4374 a         2296 c         2680 g         3722 t
ORIGIN      
        1 atttttcact acaatcactt tcccgtttcc atctaccaca gtagaaccac aatttctaca
       61 ggtatgggga gcaggtgaga aaacagcatc gacgatcaac gtctttttct tctgaaaggt
      121 ctcgtaagag acctctgtaa tcatcaaatc tttctctatt aatcgcagca tttttttgat
      181 agaatcattc atatagcata tcgtcctctc agttgtttat tttgtcgtga tttaatcata
      241 ctagagaacg atatgttttt taatacctaa aataaaaatg gggctgaaga atcaattctg
      301 attcatcagt cccataaatt atagagcctt tttttcttgg tttcagattg ggttttccta
      361 caaaatattt ttatctttgt tgaataggaa acaaaaaaac aatataatga aagaaaaaga
      421 aggtgtagaa atggataaaa gacaactgct aatagaagaa tatctggatt tagctaatga
      481 gattattcat cgtaataaac cagaaatgga aaaagaattt gcaggattta ctctaaatga
      541 actagaagtg attgaacata tcgggaaaat ccctgatcct aacgtgacaa aattagcgaa
      601 tgctagttac atgactagag gagccatcag taagctaaca aaaaaactga tagctagagg
      661 gatcataaac acttatcaaa gcgaagagaa taaaaaagaa atctattttc aattgacgcc
      721 aatcggacaa aaaataagga atagacacga gcaactccat caaaaatggg tacagcgaga
      781 tgctactgta tttgaaaata tgtcaaaaga agaatttgac acagtatttc gttttatcgg
      841 tcgatacaga gaatttatac gaagtagcaa atgaagctac tattttttat tgtagtgata
      901 ataggcaaaa atcataagca aaaatccgaa taccgtcgga agaaatggtg ctgcagcata
      961 aagctgtcct gcgattagcg ggccgatgac gcgcgataga gattgtatac tttgggtacc
     1021 gcccattaca agaccttgct ggttatctga gacagaattg gatagttggc cattgaatac
     1081 aggagtaaaa atagaatcac cgaaaccata acagataatc ccaaataaaa acaaaatcgg
     1141 cagtagaaga attccagata atgtgatgaa tagataggcg aggatttcac tgaacatccc
     1201 tattcttgtg atctgctgtt ctgaaaattt tttgagcaat cgaggcataa tgaacaattg
     1261 cgagacagta tccaagattc caatcaaaga gaagcttaaa ccaaccaacc cagccttcca
     1321 ctgaaaggcg tcaatcgaaa attgagaaaa gatagattga agagagccag ctgccaacca
     1381 aacagcaaaa cctgctgtca ataaaggaat aacggatgaa atcttgaata attgttgtaa
     1441 ttggtgaaaa ggtcttacat gggagaaact taaatctact gaacgttttt ttattggaag
     1501 gctttctagc ataaatgtgt agccataaac ggcatttaag aaagtaaaga gtgctccaat
     1561 aaatatagga acagaattcc ccaactcagc taatagaccc cctataatag gacccagcgt
     1621 tgttcctata ccgactaaag cacccatcca tccaaaaact ttggttcttt cattaggttc
     1681 cgtgatgtcg gcaaagtaag catataaggt ggagatttct cctgccgtca atccttcaat
     1741 gatacgacca aggaacaaca tccatatcga atttcctaaa ccaaaaagca aatatccgat
     1801 acttgatcct aataaactga taataaggat cggatgacgc ccaaaatgat cacttaagct
     1861 accgagaatg ggggcagata agaaggcagc tagagcataa acagacatga gcaaagtgat
     1921 atagaaagct tgctgatgta tggagtgaga ataaggcagc gttaaaaacg gaagtacagg
     1981 actgacgata gtaaatccta atccagtgaa taagacagag acgtatccaa aaactttaga
     2041 atgtttattt gtgaaactgt acatgtaaaa actcctttat gcaataatgt taacttggaa
     2101 acaaaaatag tgtatagtaa ttttgtttcc ttgtcaacat tctaaggaac agcgaaatct
     2161 acttaattta tttattccga aaagtgaaga tacgcatcaa aaacatgaac aaacaaaaat
     2221 caagtagacg acattgtaaa tctgaccgat cagtgaagta aatagaaaag aaacctgttc
     2281 ttgcttccca tgtttttttt acgtatactg tgattgagcg gaggagaaat catgttgaat
     2341 ttagaaaatt acttaagcgc tggacaaaca gtcatatcta atcttttact taaaaattat
     2401 cataggatcg gtctacaatc tgaagaattt ttatttgttc tacagttgca tatggcacag
     2461 cttgaaggag atactttccc tgatttgcag atgattgcta tggatatggg aatcaaacaa
     2521 gatcagattt ttcaaatact ggatcgtctc gtaacaaatg gatttatcaa gatagaaacg
     2581 acgattgtca acggtaaaaa agcagatcga tataatcttt accccatcta tgatctatta
     2641 ggtgagtatt taaaaacaca agaaaaaaaa tacgaagaaa aaacacaaga aaaagaaatc
     2701 cagtcagtgt atcaattatt tgaacaagaa tttggacgcc cgctttcttc gatcgagttc
     2761 cagcggatcg gacaatggct agaagaagac cattatcagc cggaaatttt gaagctagca
     2821 ctgcgggaag ccgtattaaa tcaggcttat agttttaatt acgttgaccg cattttgcta
     2881 tcgtgggaaa gaaaaaatct acgtacaaaa caacaagtgg aagaagacca aaaacgaaga
     2941 aaacagcagc ttcttcaaag agaagtagaa cagtcagctc aacaagaaga attgccgaaa
     3001 gtctcactga aaaattggtt ggaggagtag cggaatatgt taagcaaaca aaaaacaatg
     3061 gaagctctag aaacgatgta tggaatgttt cccgaagcac atggagaact caagcacaat
     3121 aatccatttg agttattgat tgcagtgatc ttaagtgccc aggcgacaga tgtatcagtg
     3181 aataaagcaa cgccagattt gtttgcctct tttccgacac ccgatgcgtt agcagaagct
     3241 tcaatcgatg aaatcattct taaaataaaa acgattggtt tgtatcgaaa taaagcaaaa
     3301 aacatcaaag cgtgtgcaca gcagctgatt gaacgtttcg atgggcaagt gccaacgtca
     3361 agagaagaat tgatgtctct tcctggtgta ggcagaaaga cagcaaatgt cgtattgggg
     3421 gatgcattcg ggataccagc aatcgcagta gatacccacg tggaacgtgt ctcaaaacgc
     3481 ctgaggatct gcaaactaga tgctacggtc atggaagtag aagaaacact gatgcggaaa
     3541 gtaccacaag aattatgggt aaagacacat catacactga ttttttttgg tagatatcat
     3601 tgcacggcaa gaaatcccaa gtgcgaggta tgtcctttgc tatcaatatg tcaagatggg
     3661 aaaaatcgga tgcgtctaaa agaaaaggcg ctaaaaaaga aaccacgcct gtagacgtgg
     3721 tttctttaat tgcaaataaa tgtatgaatt atcttgttat tatggagaaa agctgtttcg
     3781 tttatctttt ttgcatgaaa aagtaaatgt acatactcag tagctaggat ggtaacttat
     3841 tacaatttat tgcgataaaa ataaaagttg ttatttttat tgggaaaata cccgatgtag
     3901 aaaataatgc cttccaatat acctataaaa taagtccagt attccaaagg attatataaa
     3961 taagtgacgt atctatctaa aggtgtaata aaaatgataa gtgataataa aaaaatacca
     4021 tttataacta aacataaact aatggatttg ggcggtttca ggctcatcag aaaaatatag
     4081 attctggtga acaacaacca taaaaaagtg agaatcattg catgagagct tctttccata
     4141 aattttcctt taagagtagt gcttaaaagt acagaaaaaa taataaatgc aaggatagga
     4201 gcaattaaag taaatttatt taataataaa caaaattttt cagctttttt attcttggaa
     4261 taacgaggta ttgttttcga taaaaaaaga tggtgcagac aaattatgat aattaagcat
     4321 actatcagat aactcaaaat gaagccttct ttcaaaaaat tattcaaaac catatattgt
     4381 attttttatt tgataataac aatgggatta ttaagaagtg gcactaaata aaagactagt
     4441 gtgtatttag ccgatttaat tataaacaag taaatggata aagtatatgt aatgataaaa
     4501 gaaaaatgga ttttctaatt tttaagctaa atgttagatc acacatgtat atgctggata
     4561 gtcttataaa aaatcatgta atacagcttg gtacatgatt tttatttgta gctgtttttt
     4621 acatagacac aaaaaagaaa ccacgcttgt agacgtggtt tcttttttac tatctgtttc
     4681 cagaagctga ggtgctgctg gatggtgtat ggtcatttgc agcatccgct ccgctagttg
     4741 ctggctcact ggaagaagca ggaggagcag atgaagacgg tgtcgagctt tcttcggatg
     4801 aagaagaagg aaccgttgtt gaagacgctg gctcgcttgt ttctgctgtc gtgctttctt
     4861 ttgaggactc agcagttgat tcgctttgac tagtagagct agagctttga gtcgttgtct
     4921 ctgttgttga gcttccagga gtctggacat agctggaaga tggaatagtt gttgatggtg
     4981 taattgcatt cgatctagct gtatattgat ctttgtagta cagttcaccg cccacacgaa
     5041 ttaatccgct tggcatctcc cagtctgtat ttgtcacgtt agctgaaaca tactgcataa
     5101 gctcgcgata aacatcagag gctacgtgtg acgattctga agtgacaggc gtcatttttt
     5161 tattgtaacc tgtccacacg gaaatcgaat aatttggcgt atagcccgca aataggatat
     5221 ctggatacac cccagaagaa ataccaagtt ttgcatactc gtcatctgtg taattggatg
     5281 ttccggtctt accggcttga tataacccag cgatttgcgc attcgtacca gttccttcag
     5341 tgatcgtatc ttttaaaatg tctgtgatca tataagctgt ttctggagac atggctgttt
     5401 ttccatctgg ctcataagtt tcttctgttc cgtcttggaa gacgatttta ttaacatatt
     5461 gaggtttgta ataagtccct ccattggcga aagccgcata ggctgctgcc atttttaagg
     5521 aagaagctcc gtattttgtc ccatcttgtt cttccgtatt actagagatc gcattcgatt
     5581 gatggatcgt actgtattcg atcccaagat tttttaagaa agaagccact ttatctgaac
     5641 cgacttcatt gaataatttg actgctggaa cattacggga taagtaaagt gcttggcgta
     5701 aagtaatggt gcccatatat tgattatccc agtttcctac aggagtcgaa gtcccttcat
     5761 agttatacgg tgcgtcagta atagtttttc cagtagaata tttcaaatat tcaaaagctg
     5821 gtccgtaatc tgtgacaggt ttcatcgtag aaccaaaatc acgggaagta ttcactgcta
     5881 agttgttgcc taaagttacg tcttctgcga tgtgacgtcc gccaatctgg gcttttactt
     5941 tcccggtatt ggtgtcgata agggtggagg caacttgcat ctcgtcgtct gggtaagaga
     6001 catactgatc cgtgttgacg atatcatata gtttcttttg ggcgtccaga tccaaattcg
     6061 tataaatctc taaaccgtct gtgtagacat tcttatctgt tttttcttgt acttcattga
     6121 tgacttcttt gacataatta tcgacgatct tagtattgtc atcggattga gttagttctt
     6181 gcagaccatc cgttaccggt acattaacag cttgatcata ttctgtttga gagatttttt
     6241 cgttttgaag catcgtatac aaaacagtat ctcgtctttt cttcgcctga tctggataaa
     6301 cataaggatc ataggcggaa ggggcttgag gcatcccagc aagcaatgct gtttgcggta
     6361 aagaaagttc tgataatttc ttaccaaagt acatctcaga agctgtctcc atcccgtaca
     6421 agccgtttga catatacact ttatttacgt agtaggtcaa gatctcttgt ttcgattttt
     6481 tttgttccaa tcttacagcc atccacgctt cttgggcctt gcgtttcaga gtctgatcct
     6541 cggcactggt ggagaagaag gaaagtttga tcaattgctg tgtcaaagta cttccgcctt
     6601 gcagtccgcc agaggtaaag ttagagaggg cagaaccgat gatccgaata gggtcaaccc
     6661 cgatgtgttt ataaaaacgg cgatcttcta ccgacacgat cgcatcttct aatgttttcg
     6721 gtaattcatt cgcagaaatt ttttcacgct tttctgcgcc taaatcttcg aatagttcgc
     6781 catcttgtgt atatagtttg gaagatacgg tagcgtctaa ttttttatcc gtcaattcgg
     6841 gcgcatcttt tgcgtaatac cagaaaagtc ctacacctgc taaaaagagg atacagaaaa
     6901 atgagagtat tcctaaaagg atcttgataa ataatccttt tttatgtgtt ccagaggact
     6961 ttccagaacc tttgccagaa ttcttcttca cactcttttt aggagtaggc tgtttctgtc
     7021 gtctagagct tctagtttgt tcatttgcca ttcttgcttt ctccttcaat agataatgtt
     7081 gataaataga agtcaaccgc gtccaaataa ggaatccgcg gagaaatacc agttttgatc
     7141 tctattccta gttcttcgat caaagataaa ggtagtgatt tgcgtccttt ttccttttgg
     7201 gcgtcccagt aagcaatcaa atgaacacta ttcaaataaa aacagcgctt caaagacgaa
     7261 aaccataaca agacaaagca gaccccattt tgttcgaggc atgctttcat atgttcgatt
     7321 tgatgggcat ggaagttttt aaagggaaaa gatgttttgt tcttggtttc ttttgcttca
     7381 aagtccaagt aaaagcctcg atagacgcca ttatagtctg tagttgaggc ttgggtaaag
     7441 taggcttcct tgatcacagc agcacttctc ttaggatagt ctactttcac gatttggata
     7501 ggggtaggct ttttatggat aaccgccaac ccgcgggaaa gataatattt attactttca
     7561 ttgattgctt cttcaaagcg catcccccga ttgccgaatt cagtgatctg atttcttttt
     7621 tcttgaattt tttcgacggg agaggcattc ttataataag gttggccatt tggatagcgc
     7681 aataccatct ttaatcacac tcctaggcca cattatagca aaaaagcgga tagaaagaaa
     7741 aggaatctga gatggataag tcaaaagtaa tctatgtgtc tgggtatcga agtttcgaac
     7801 tcggtgtttt taaagaaaat gatcctaaaa tccaagttgt taaaaatgtt ttaaaaaaag
     7861 aactccatca gttagcagaa gaagggctgg aatgggtact tgtcagtggg aatttgggcg
     7921 tcgaactatg ggctgtgcaa atagtagcgg aattgaaaga agaatatccg gaactatctc
     7981 ttggtatttt gtatcctttt tctgattttg gtaataactg gaatgaaggg aaccaagaaa
     8041 aaaaacaatt agcagaacaa ttagcagatt atgtcgaagc tgttagccat caaccctacc
     8101 aatcacctag tcagctaaag aatcacactc gttttatact tgagcataca gtgggctgtc
     8161 tgctgatcta tgatgaagaa ttccctggaa aaacgaagta tttttttgaa gatgcacaga
     8221 attaccaagc agatcatccc tacgaaattc ggctgatcag tatggacgat cttcaaaatt
     8281 ttagtgaata atcgatattg tgtttgattt atcaactttt ttcctataca atgaaaaagg
     8341 tagaaatgtt attacgtaaa tgaaaactag aggtgtaaat atggcgaatt tggtttatag
     8401 tcctaaagac attttacaac aagaattcaa aacaaaaatg cgcggctatg atcccgttga
     8461 agttgatgaa ttcttagaca atatcatcaa agattatgaa acttacagca aagaactcct
     8521 tgctttacaa gaagaaaacg atcgattgag tgcaaaagta gctcaattat ctaaaactca
     8581 aggagcagct caaacacgcg tgcaacaaac agaggcacca aagagcgcag cagtgaccaa
     8641 ttttgatatc ttaaaacgct tgtcaaatct tgaacgtgaa gtatttggta aaaagcttga
     8701 tcaacaagca agtgcagtca aaccagcaca acctaatcca aataactaca caaatgcaga
     8761 cacaagctta gatgataatg aaaaaacacg tcaattttaa tttttgatta atgaatttgc
     8821 ggttttcggg taatcgcggt ctgacttgat caggctgagg aaagtccatg ctcgcacagg
     8881 ctgtgatgcc tgtagtgttc gtgcttagcg aaaccataag ctaaggtact ctttggagta
     8941 acggcaggaa aacaagctaa ggcttcggct atgcttaagt atccttgaaa gtgccacagt
     9001 gacgaagcgg ctggggaaac ccatccggtg gaacgcggta aacccctcga gcgagcaacc
     9061 caaacaatgg taggggcgct ttttgtctgg aagaagaaca ggacaaaaag gcagtataac
     9121 tgcagataga tggttaccgc tttgtttttt ctccctggaa aagcaaagta cagaacatgg
     9181 cttatagaaa accgcaaaca tcagggaatt aggtcgtgac aaaagtaatg cgttataaga
     9241 aacaagaaaa acatttgaaa gctatttttc aatacttcag atgaatcgtt cttattacaa
     9301 aacaaacttt tgtatcaccg gttattcgga atttgagtaa aagtgtgggg taggactgat
     9361 gtcccacctc ctttttttat aaataaggag attgtgtatg gaaaaaaaca ggaagttcaa
     9421 cctcgtcgca actgcggcaa gcgggctaga agcactggtt ggtaaagaat taagagatct
     9481 tggaatcgaa tgccaagttg agaacggacg tgcacgtttt gaaggaacaa tggaaacgat
     9541 cgctacagct aatttatggt tacgtacagc agatcgagta aaaatcgtgg ttggggaatt
     9601 cgatgcgtat acgtttgatg aattgtttga aaacgtaaaa gcattgcctt gggaagattt
     9661 tcttccacta gatgcagctt ttcctgtagc tggaaaatcg atcaagtcga aactatatag
     9721 cacacctgat tgccaagcga tcacaaaaaa agcaatcgtt gaacgtctcc gtacctatta
     9781 tcaccgtcca gcttctgtac cactgacgga aactggcgca cattttcagt tggaagtagc
     9841 tttgctgaaa gaccatgtga tggtaactct ggatacgaca ggaccaagtt tattcaaacg
     9901 tggttatcgc ttagaaaaag gtggagcacc attgaaagaa aacatggcag cagcacttat
     9961 tatgttgaca aattggcgaa aagaccgtcc attttatgat cctgtatgtg gttcaggtac
    10021 gctttgtatt gaagcagcct taataggcca taatatcgca ccaggattca atcgtgagtt
    10081 tgcttgcgaa tcttgggatt ggttcagtca agaaatcatg gaaaatgttc gatcagcagc
    10141 cgaagaaaaa gcagattatg atattgaatt agatattact ggttcagata tcaatggacg
    10201 gatgattgaa attgccaaag ccaatgcaga agaaatcgga ttaggctctt cgattacctt
    10261 taagcaacaa gcagtcaaag acttcaaaac ggataaagaa tacggggtca tcgtggctaa
    10321 tccgccttac ggagaacgtc taggagaaga agaaactgtt cggaaattat ataaagaaat
    10381 gggcgatgta ttccgtccat taaaaacatg gagtaaatat atcttgacta gcgacttagc
    10441 gtttgaggaa ttttacggac aaaaagcaac caaaaaaaga aaattgtaca atggtgcatt
    10501 gcgtacggat ctattccagt attggggaac tcgtccgcct agaaaaaaag agaaagacga
    10561 ataatcttac taattgattc attcaattgg atgtttggag gaatagggaa tgaaagaaaa
    10621 agagttttta caagaagtaa aagaaatcaa tcttctacaa caagctttag gaatcctcga
    10681 ttgggataca caaacaggta tgcctgaaaa agctagtgca taccgaagtg aagtagacag
    10741 ctatctttac agcatttatt tttcaaaaaa aatcggtcca aaaatcaaag aagccattcg
    10801 ctatttttct gaacatccgg aagaattgtc ggaagttgga actgccgttt ttgccaaagt
    10861 aaaagaagag tatgatttgg aacatcgcgt accggaagat cttatgagaa aatatacagc
    10921 tgccgtttct tcagcacacg gacaatggca aaaagctaga gaaacacaac aattttctga
    10981 ttttcaacac gcattgaatc aaaatattga attaacaaaa cagttgatac cttactggag
    11041 aaaagatgaa aagacgaatt atgatgtttt gctgaatcaa tacgaacccg ggatgactgt
    11101 cgaaatcctt gataaggtat ttgatcagct taaagaagga attctttcga tccgccgtac
    11161 gctccaagaa aaagggactg aacctgaaac agacttttta aatcggagaa tgacgaaaaa
    11221 acaacagaag agatttgtag tgaaagtaat cgaacaactt ggttatgatt ttagtcgtgg
    11281 tcgtttagat gacactgtcc acccatttat gactggaatt aatccgaatg atgcacgaat
    11341 cacgacacga tggaacgaaa cagatttcaa aatggctgtt tttggagtga tccacgaggc
    11401 tggtcatggt atgtatgaac aagacatcga tgataaatat gcgtatacac cggtttatga
    11461 aggtacatca atgggtatcc atgaatcaca atcgttgttt aacgagatca ttattggaag
    11521 tagtcgcagc ttctggaaaa agcaatatcc tttctttcaa gaatgtgcag aaggaacatt
    11581 cgatgatatt ccttttgaca aattttatcg ttcattgaac catacaaaat caagtttggt
    11641 tcgtatcgag gcagacagtt tgacttaccc tctccatatc atcattcgtt atgaaatcga
    11701 aaaaatgatt ttcaatgaag gggtagatgt tgctgaacta cctgaaatat ggaatcaaaa
    11761 atatgaagag tatctgggaa tacgaccaac aaatgatgtg gaaggcatcc tacaagacgt
    11821 tcattggtca ggtgcaagct ttggttattt tccctcttat gcattagggt acatgtatgc
    11881 ggcacaatta cttcattctt tgcagcaaga aatagatgtg gaaaatgttc tagcgtcaga
    11941 cgattattct ccaatcaaaa actggatgtc agagcatatc catcaatatg gtgcatctag
    12001 aaaaccaaat caattaatca tggatgcaac acatgaaccg cttaatccgc aatacctgat
    12061 cgactatatg aaagacctgt attttaatgt atatcaggta aaataaaata caatttacaa
    12121 agatagctga aattcatcta atctatagat gttttcagct atttacttaa gaaagaagtg
    12181 gaacgaatgg ataaattaca agtgatcgct gattatagta tggaccaatt agcgcatgat
    12241 caaacaggac atgggagcga tcataccaaa agagttgtca agttagctga aaaaattttg
    12301 gagacggaac cgcaggcaga ccgctttgtg acgcttgcag cagcttacct acatgatacg
    12361 attgatgata aagtcgttaa aaatgagaac gaggcaaagc aacagcttcg tgtattcctt
    12421 cgctctttgc caatagtaga ggaacagatc tcgatgattt tttccattat cgaaaatatg
    12481 tccttttcta aaaatctctc tgaagcggcc gaactatctc tggaaggtaa gatcgttcaa
    12541 gacgctgatc gtatcgaagc attaggagca atcggcattt tgcgtactgc ttatttcggc
    12601 ggtggacatg ggcacccgat ttttgatcct gaactgtatc cgcaaacatt caaggacaaa
    12661 gaaaattacc gaaaaggcac gacagtgatc aatcattttt atgaaaaact gttcttgctg
    12721 tctgataaaa tgaatactga ttacggatat gaagaagcca aacgaagaga aaccttcatg
    12781 cgtgaattct tagaagaatt ttttctggaa tggtctattg acgatgaaaa ttttactcca
    12841 gacaattgga tcaaaaataa caaaaaatga tggaggttgt gacagaagtg gtcagctcca
    12901 agatatttcg gatcattttc cgtaaaagtt acttctggaa cactgtttac caagaggtcg
    12961 tgagcctgcc gttcagctcc gagtcacaag gaacaatttc aaaaaatagc ttctcgtgtt
    13021 tgatgaatat tgtaacttgt gattcggaat tggcaggaga acaccgttta tt
//
LOCUS       DASHXG010000068        12992 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.071, whole genome shotgun sequence.
ACCESSION   DASHXG010000068 DASHXG010000000
VERSION     DASHXG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.071"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(94..1242)
                     /locus_tag="U2R59_002371"
     CDS             complement(94..1242)
                     /locus_tag="U2R59_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEM8966716.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(1364..1960)
                     /locus_tag="U2R59_002372"
     CDS             complement(1364..1960)
                     /locus_tag="U2R59_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEM8966717.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(2160..4802)
                     /gene="alaS"
                     /locus_tag="U2R59_002373"
     CDS             complement(2160..4802)
                     /gene="alaS"
                     /locus_tag="U2R59_002373"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEM8966718.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            5190..5621
                     /locus_tag="U2R59_002374"
     CDS             5190..5621
                     /locus_tag="U2R59_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966719.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(5666..7015)
                     /locus_tag="U2R59_002375"
     CDS             complement(5666..7015)
                     /locus_tag="U2R59_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEM8966720.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(7085..8248)
                     /locus_tag="U2R59_002376"
     CDS             complement(7085..8248)
                     /locus_tag="U2R59_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HEM8966721.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            8377..8700
                     /locus_tag="U2R59_002377"
     CDS             8377..8700
                     /locus_tag="U2R59_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966722.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(8883..10232)
                     /locus_tag="U2R59_002378"
     CDS             complement(8883..10232)
                     /locus_tag="U2R59_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8966723.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(10301..11254)
                     /locus_tag="U2R59_002379"
     CDS             complement(10301..11254)
                     /locus_tag="U2R59_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HEM8966724.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(11356..12546)
                     /locus_tag="U2R59_002380"
     CDS             complement(11356..12546)
                     /locus_tag="U2R59_002380"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HEM8966725.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         3747 a         2729 c         2237 g         4279 t
ORIGIN      
        1 ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact ctttaaatta
       61 aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat tgtgatcaaa
      121 cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta agattctttc
      181 tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt gcagcgtttt
      241 tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt caagaagaat
      301 ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca ttggatccaa
      361 gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca gatcaataat
      421 cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg atgcaaagcg
      481 tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat catcgcaagc
      541 atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc ctaatagttc
      601 gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg ctaaagcaaa
      661 acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg aaagcaatac
      721 agccagtgta gtaaagacat cattataact atctgttgct gtagctctca atgtttcaga
      781 atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca aaaagatgga
      841 aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat ggatgatttt
      901 ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg aaacaaataa
      961 cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg ctggctttgc
     1021 agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata gactgttcac
     1081 tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct tagagacaaa
     1141 caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt ttgtccgctg
     1201 ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta ccccttctag
     1261 tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc ctctcttcct
     1321 ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct ggtttcaacg
     1381 gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca cctattgctt
     1441 ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga gcagagtcta
     1501 caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct aacactaaga
     1561 ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt attgatttat
     1621 ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt actctgggaa
     1681 ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt ggcatggcat
     1741 aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca tcttttgggc
     1801 ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta atgaatccta
     1861 atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct aacaagatcg
     1921 cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc ctttttattt
     1981 atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga atccgaccat
     2041 ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt tgtcttcgcc
     2101 cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac gtaaacgccc
     2161 tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc agcaggattt
     2221 ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac tttcggtgcg
     2281 attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt cgtcattgcc
     2341 gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc tgaaatattt
     2401 ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac ttttacttgt
     2461 gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc accagcttgt
     2521 tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct tacttgctgt
     2581 tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac aattgttgct
     2641 acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt acttgttaca
     2701 gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt gaagattccg
     2761 atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca gccgccaata
     2821 tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc acccatgttt
     2881 ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca gattttttcg
     2941 ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa gtgggtaaag
     3001 tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg ctcgccaagt
     3061 acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat gatccgattg
     3121 cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg tgcttttact
     3181 tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac aactgctacg
     3241 atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc catttctgca
     3301 tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc attcaaaaga
     3361 gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt gtatccaatg
     3421 aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat tgatttttca
     3481 gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc aaaaccagca
     3541 tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac cgggaagcca
     3601 tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt ttcgtttttt
     3661 acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc attgaaacgt
     3721 tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac ttcaggataa
     3781 taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc ttgttcaata
     3841 cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac ataccctctc
     3901 ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg aatatgatct
     3961 gcgattactt tgtaagaaat atctgttact gggttttcac catattttac ttgtttgctt
     4021 agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt cgttgacgca
     4081 tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt tttatgagga
     4141 agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa gttccagatt
     4201 tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc tgctaaatcg
     4261 ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg gcctgcaccg
     4321 atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc aacttcttca
     4381 tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag tttttctgga
     4441 tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat ggcttcattt
     4501 ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg gtgccgtgct
     4561 gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt tgtgattctt
     4621 ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac accagagttg
     4681 atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc aatcgtatgt
     4741 cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact taattgtttc
     4801 atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag ccaaggacga
     4861 aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta aactcgataa
     4921 cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg attagtgact
     4981 attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat catatccttt
     5041 tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat ttttattttc
     5101 atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga atcaatacat
     5161 ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg gatgaatgga
     5221 tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa gggattcctg
     5281 cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta tttcttgatc
     5341 aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc ttcaagccgg
     5401 aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag ttgcttgaag
     5461 ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta gctgaaatga
     5521 cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct tttattgaag
     5581 atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag attgtgacac
     5641 gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt ttacgagcag
     5701 tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct gcaattgccc
     5761 aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc acaagaccaa
     5821 tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta ttacgatcgt
     5881 atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg cccaattttt
     5941 ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc gttcctttta
     6001 agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct tctggaattt
     6061 ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct aaatcagtcg
     6121 ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt ctctctcttg
     6181 gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag taatcggcaa
     6241 tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga tgaccaattg
     6301 tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc agccaatttt
     6361 caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga ttttccatgt
     6421 attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact aaaaactgca
     6481 gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc atatccaatg
     6541 tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc gcttgttcat
     6601 tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt tggtgatgca
     6661 gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca cggatctccg
     6721 gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct agttccctac
     6781 ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt tcaaacaaag
     6841 gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg atattttttc
     6901 cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg aagccctttg
     6961 cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta ttcattcgtg
     7021 cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa gcgtttttgc
     7081 tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca gtatatgtgt
     7141 gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc aagatattta
     7201 aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca ctcatctgca
     7261 acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac cagcttaaac
     7321 cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa gaaattcgtt
     7381 cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc catccattgg
     7441 ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac cagatatgag
     7501 aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc aaattaataa
     7561 gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat gagacagtct
     7621 ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata aatgtaaata
     7681 acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa tcattcacat
     7741 caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc gtcaattcaa
     7801 aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc cggaaataat
     7861 atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt tccaaaaata
     7921 cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat accgtgttgt
     7981 ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct gtcatttggg
     8041 caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac aataaataaa
     8101 aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac tttcgatatt
     8161 cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca atcagcgcaa
     8221 aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg tatctctctt
     8281 atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct catttctttc
     8341 aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta ctttgttttt
     8401 ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag aaaaagaact
     8461 acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct agtcttcaat
     8521 cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca tgctttgtct
     8581 aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc tggttgcttg
     8641 gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa atcaaagtaa
     8701 aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca tcgtagacaa
     8761 aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca cgtactcctc
     8821 atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt cgaatgtttt
     8881 agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa tactatcccc
     8941 atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt ccctccaatg
     9001 attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa caaatcaggt
     9061 tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat ccaaatgaca
     9121 aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc aatagcgatg
     9181 actagctcta agatacctgc ggctacagga actttagttt tatcatgaag tttagcaaag
     9241 agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg cattccagta
     9301 agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt gaccagtctt
     9361 ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct gtttcctgcg
     9421 actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata aacgatcatg
     9481 attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt tttcaattct
     9541 cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc tagcaagccc
     9601 gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa cagttggaag
     9661 tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg aataagcttg
     9721 cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa attgatcaac
     9781 aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga aagaccaaat
     9841 agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc tggaaaataa
     9901 atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat ccgttcgata
     9961 tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc tgttagtcct
    10021 gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact ggcggatcct
    10081 gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac tgtgcccata
    10141 acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc tatttttact
    10201 tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata ccatagccaa
    10261 tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc tctaccaatt
    10321 tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat ttcggcgaaa
    10381 agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat tctgctattg
    10441 actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt ttttgaatag
    10501 atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca tttcgatgaa
    10561 ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca tctggcatat
    10621 acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct tctttgattg
    10681 ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag gttgcataag
    10741 aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca taataataat
    10801 cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga cgctgaagag
    10861 tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt gaacttggcg
    10921 taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc ccagtcacgt
    10981 tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga gcagccaaat
    11041 gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg taatccatta
    11101 catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt atatctgtcg
    11161 caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct gaaccaattt
    11221 gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat cttttttact
    11281 actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt aaatagacga
    11341 aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat aaactgctac
    11401 tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga tcctgcctgt
    11461 cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt cgatcagctt
    11521 cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa taggtgtttc
    11581 agacataccg atgttatagc ctactttttt caattcttct ttaaaataat tagcattttc
    11641 ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag ccaatgcagc
    11701 tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc tagctttcaa
    11761 ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta tagctttcga
    11821 taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga cggttcctgc
    11881 accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca gtccatattt
    11941 ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg agaaaacacc
    12001 atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct ttgctttttt
    12061 ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg ataagcggca
    12121 accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt cttttgtcat
    12181 tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga ttgctgcttc
    12241 tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca gcgaaccatt
    12301 gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa tacatgcttt
    12361 tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat tgatcatctt
    12421 ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga tcgtattgta
    12481 taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta gttctttgga
    12541 agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac atatatcgtg
    12601 tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg attatgagaa
    12661 ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact tatatagtat
    12721 gaacaattac cttttagata atgatctatt ttactctacc tgggcagata aatacaacac
    12781 aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt aatttattta
    12841 ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca atttttaatt
    12901 ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag gactgtgaca
    12961 aaagtcttgt cacagtccta ttcttccgaa ta
//
LOCUS       DASHXG010000069        12762 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.072, whole genome shotgun sequence.
ACCESSION   DASHXG010000069 DASHXG010000000
VERSION     DASHXG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.072"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="U2R59_002381"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="U2R59_002381"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEM8966726.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="U2R59_002382"
     CDS             complement(2260..2511)
                     /locus_tag="U2R59_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEM8966727.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="U2R59_002383"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="U2R59_002383"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HEM8966728.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="U2R59_002384"
     CDS             3461..3679
                     /locus_tag="U2R59_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966729.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="U2R59_002385"
     CDS             complement(3968..4480)
                     /locus_tag="U2R59_002385"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEM8966730.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="U2R59_002386"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="U2R59_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEM8966731.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="U2R59_002387"
     CDS             complement(6933..7376)
                     /locus_tag="U2R59_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HEM8966732.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="U2R59_002388"
     CDS             complement(7377..8165)
                     /locus_tag="U2R59_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8966733.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="U2R59_002389"
     CDS             complement(8162..9103)
                     /locus_tag="U2R59_002389"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEM8966734.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="U2R59_002390"
     CDS             complement(9280..9867)
                     /locus_tag="U2R59_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HEM8966735.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="U2R59_002391"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="U2R59_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEM8966736.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="U2R59_002392"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="U2R59_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEM8966737.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3528 a         2858 c         2269 g         4107 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tc
//
LOCUS       DASHXG010000070        12735 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.073, whole genome shotgun sequence.
ACCESSION   DASHXG010000070 DASHXG010000000
VERSION     DASHXG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.073"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="U2R59_002393"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="U2R59_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEM8966738.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="U2R59_002394"
     CDS             complement(323..892)
                     /locus_tag="U2R59_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEM8966739.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="U2R59_002395"
     CDS             1078..1980
                     /locus_tag="U2R59_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8966740.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="U2R59_002396"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="U2R59_002396"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEM8966741.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="U2R59_002397"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="U2R59_002397"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEM8966742.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="U2R59_002398"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="U2R59_002398"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEM8966743.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="U2R59_002399"
     CDS             8548..8733
                     /locus_tag="U2R59_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HEM8966744.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="U2R59_002400"
     CDS             complement(8795..9991)
                     /locus_tag="U2R59_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEM8966745.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="U2R59_002401"
     CDS             complement(10161..11597)
                     /locus_tag="U2R59_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEM8966746.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="U2R59_002402"
     CDS             11890..12699
                     /locus_tag="U2R59_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8966747.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgaca
//
LOCUS       DASHXG010000071        12614 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.074, whole genome shotgun sequence.
ACCESSION   DASHXG010000071 DASHXG010000000
VERSION     DASHXG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.074"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            157..729
                     /locus_tag="U2R59_002403"
     CDS             157..729
                     /locus_tag="U2R59_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEM8966748.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            874..1578
                     /locus_tag="U2R59_002404"
     CDS             874..1578
                     /locus_tag="U2R59_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEM8966749.1"
                     /translation="MTKHIHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1806..2144
                     /locus_tag="U2R59_002405"
     CDS             1806..2144
                     /locus_tag="U2R59_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966750.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2129..2983
                     /locus_tag="U2R59_002406"
     CDS             2129..2983
                     /locus_tag="U2R59_002406"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEM8966751.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3130..3363
                     /locus_tag="U2R59_002407"
     CDS             3130..3363
                     /locus_tag="U2R59_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEM8966752.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3561..5465
                     /locus_tag="U2R59_002408"
     CDS             3561..5465
                     /locus_tag="U2R59_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEM8966753.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5775..6137
                     /locus_tag="U2R59_002409"
     CDS             5775..6137
                     /locus_tag="U2R59_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966754.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6154..6765
                     /locus_tag="U2R59_002410"
     CDS             6154..6765
                     /locus_tag="U2R59_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEM8966755.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6867..7775)
                     /locus_tag="U2R59_002411"
     CDS             complement(6867..7775)
                     /locus_tag="U2R59_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEM8966756.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7817..8131)
                     /locus_tag="U2R59_002412"
     CDS             complement(7817..8131)
                     /locus_tag="U2R59_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEM8966757.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8430..10361
                     /locus_tag="U2R59_002413"
     CDS             8430..10361
                     /locus_tag="U2R59_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEM8966758.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTVMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10654..11205
                     /locus_tag="U2R59_002414"
     CDS             10654..11205
                     /locus_tag="U2R59_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8966759.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11518..12060
                     /locus_tag="U2R59_002415"
     CDS             11518..12060
                     /locus_tag="U2R59_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966760.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4098 a         2107 c         2634 g         3775 t
ORIGIN      
        1 atttaataga gaagcctggc gtctattaag aaataatttt cttgatgagc gtcaattttt
       61 ttaacggaaa tctatcctat actaaattca gtaaagaaaa aggaggaatc aaagaaagct
      121 attttaaaca aaccaaaatt ataggaggaa taaatcatga ctgaaaataa agctactcaa
      181 gaaagaacac cccaagaaag attgcaagaa gaacaagaac acaaggaaca tgttcatcat
      241 acgaaaatta atgcagcggc cattgcggat catcttttag gcaacatgca tacattacat
      301 gtgaaactgc accaatatca ctggtatgta aaaggagcca atttctttac gttgcatgaa
      361 aaatttgaag agttgtataa cgaaaatgaa aaatggttcg acaaacttgc ggagcgtcta
      421 attacttctg ggcataaacc tgcttcgaca acggttgaat ttgaaaaata ttcgatgctt
      481 tcggaagatg cagttaataa atacgctaaa gcagaagaca tggttgaaaa tattatcgag
      541 gacttcagaa gcactcgtga cctaactatt cgcgcgattc gtttagctca agacgagggt
      601 gacgatgctt tagaagatac attgattgct tttaaaaatg acttagacaa gaacatttgg
      661 atgctgcaag cgttcattgg taaagaagca ttagaagatg atgacgctct tgatgaggat
      721 gaagattaag gtaaaagtag aagctgattt agggattgga attctttcca gtcctttttc
      781 cattttcttg atgtgcatca atttttttgt agtaagagac ttatataata aaagcagcga
      841 atataaacaa aataaataaa gggggagaat gaattgacta aacatatcca tcatgaaatt
      901 ggcgaccacg cagcctgtat ccgcttggtt ccaatattca atcacttaga ggatagcgcg
      961 atgaattaca ttgctgaaaa agcccacacg aaacagtatc aaaaaggaga gtttctgttt
     1021 cgttcacaag aaaaagagga tactttatat attatcaatc gtgggaaaat ccgtatttat
     1081 cgattggcag actctggcaa agagcagcta gtgcggatct tgaaccctgg tgatttcacc
     1141 ggagaatgga ccttgttcaa cccggatgca gtacacgagg aatatgccga agcaacccga
     1201 gataccgttg tctgtatgat tcagcaaaaa gatgtccaag attttctgga acaataccca
     1261 gctatttctt taaaactatt ggcggaaatg tctaaacggt tagaaagttc agaacgtcaa
     1321 acgacacaag tagccgtgga gagtgtcatt acccgtttag ttttgttttt ggcagaaaat
     1381 gtggaacctg aaatgggcaa ctctcccacc atcaccctgc cgatggcaaa aaaggacatt
     1441 gcttcctatt taggaacgac acctgagacc atcagtcgca aatttggaga attggaggac
     1501 gaaggattga ttcaacagct gtctgggaaa aggatcaaga ttcaggattt agatgattta
     1561 ttgctttaca gcgaataatc ggacacactt ttttctacac gttggtgttc tgtcgctctt
     1621 cattaacaac gggacagaac tcagtgcttt tgcttccatc tgtccgtttt tggctttttt
     1681 aagacagaac gaccttcatt cattggaaaa ataaaagcac aaacatgata accctcaagt
     1741 ttttttgttt tatttttctt taagataggg ttgtcgaaca aaacgtaaaa ataagtaggg
     1801 tgaatgtgca ttgtttttgg gtgatagttg ccatcacgtt gtcagcagcg ggggcattct
     1861 ttgtcgtccc tttcaccaag aacacgattg gcggcgaagc aaaaacgtct aacgttgttg
     1921 aggcagatag gttagctatg gaaaaagaag aggaagttgt aaaaggagcc ggcgtaatcg
     1981 gacacggaaa agtggcgtat tacgaagcga gtgaccaggg agataaaagt gtattcactg
     2041 tttggtttcc atggagctta gccggaatct tgttcagcat caccatgact agaatgacgc
     2101 gaaaaattga agaaatggag caaatagaat gggattcgta ttaggcgttt tgaatcccca
     2161 tgtggtggag attggttctg ttgtgattca ttggtatgga gtcattattg cagcgggcat
     2221 attagcggct ctccagttga gcaccaagga agcaaagaaa aaaggactgg aagaggatac
     2281 cattatcgat atggccttat gggcaattcc gattggactc ctcggcgctc ggctttatta
     2341 tgtgttattt gaacttggtt attatctgca aaatccagga caaatccttg cgatttggaa
     2401 tggcggcatt gcgatttatg ggggattgat tgcaggaggg ggtacgctat attggtatgc
     2461 aaagaaaaaa ggtacttctt tggcactcgt tcttgatatt ttagcgccca atgtattgtt
     2521 agcccagtcc attggtcgtt ggggcaattt tatgaatcag gaagctcatg gtgggccggt
     2581 tactcgtcaa ttcttggaaa atctttattt acctgaattt atcattgaac aaatgaatat
     2641 gaatggtacc tactaccatc cgactttttt atacgagtca ttgtggagtt tgttgggctt
     2701 tgtcctcatc gtcactatac ggaaccgaaa acagcttttg cgtcaaggag aagtcgcttt
     2761 gagttacgtt ttgtggtact cagtgggtcg gttcttcatt gaaggtatgc gaacggacag
     2821 tttatggatt ggcgagtgga tccgcgtttc gcaagccttg tctctggccc tgtttattgg
     2881 cgcgattgta gtatggttta tacgcagaca agattatcca ccaatttctt attattctga
     2941 tggcaataag gggcagaaaa agactattaa gatggtgaat tgagcaaaaa gataaaaaga
     3001 agtgcaaaac ttgatatgcg tcaattttcg tttgctaaaa gtgagctata ctacagttgt
     3061 aaagaggaaa aggcagtgtt cattaatctg ctgccgataa aataaaaaca cataaaggag
     3121 ataggaatta tggaaaaagc tatattgcaa ttagaaacgt tgtcttgtcc aagttgtatg
     3181 caaaaaattg aaggtgccgt gaaatcagtt aacggtattg ataaagacag cattaaagta
     3241 ttattcaact ccagcaaagt caaaaccaat tttgattcag ctgtcacttc gattgaagag
     3301 attcaaaaag ctatcgaaaa cgtaggctat ccggttctta aagcaaaagt caaggccgtt
     3361 taacagatta aatgaactag gcaattctgg aagaaaagct atttttccag gattgctttt
     3421 tttgttgcaa tccgattcga ggtgcttaga aacgataaaa gagaactttc taaacttgat
     3481 gtcagtcaat taattactta ggcaattatc ttatactgtg tttatcaata aaagagaaat
     3541 taaatttgga gggaaaaagc atgcaacaat atatattaag caagaaaaat gttatcaccg
     3601 tcatcagtgg attgttaatc gtactcggtt tcttcagtca ctttgtttta gaaaacgtag
     3661 gactttcaga gtggtctttg atcatcgcct ctgtctttgg gattacgcca attgccattc
     3721 aagcgtttca agcaatgaaa gtcaaagtca tcagtattga tgtcttagtc agtattgcag
     3781 cgattggtgc gctttttatt caaaattatg aagaatcggc tattgtcacg ttcttattct
     3841 tattcggaca ctacttggaa caacgaacat tgaaccaaac gcgatctgct atcaaagaat
     3901 tgactgaaat ggcacccgaa agcgccttga aacaaatgga taatggcgaa tttgaagaag
     3961 tagaagtgga tgatatagat gaaggggata tcttgctcgt taaaacgggt gcgaaagttc
     4021 cagtagatgg catagtcctt acgggtgaag ggcatatcaa tgaagctagc attacaggtg
     4081 aagctattcc ggtcaacaag ctagctgatg cagaagtttt tgcaggaacc attttagaaa
     4141 acggaacgat tcaaatcaga gctgaccgag ttggtgagga caccacattt ggaaaaatta
     4201 ttgaactcgt ggaagaagca caagattcta aatccgaagc ggaacggttc attgatcgct
     4261 tttctaaata ctacacacca gctgtcttgg ttctggcaat tgttgtatgg gcgttcagtc
     4321 aaaatattga gttagcaatc accatcttgg ttctaggttg cccaggcgca ttagttatcg
     4381 gagtgcctgt ctcaaacgtt gccggtattg ggaatggtgc tcgtaacggt gttcttttaa
     4441 aagggagtga agtcattcaa gacttcagta atgtggatac aattgtattt gataagacag
     4501 gtactttaac tgtcggaaac ccaaccgttg cagcgactga actgtatgaa aaagatcctg
     4561 ctgaaacgct tggctatctg gccagtgtgg aacgggaatc agatcatcca ttagcaaaag
     4621 cggtcttaaa tcaaattgga gaaacaaact tttatcctgt tgaaggaact gaagttgtga
     4681 aaggcggcgg aatcgtttca agtgtagctg gacatagagt ggctgttggg aatgtggcct
     4741 tgatggaaaa agaaaatgtc actctcagca aaaaagtgca aaaagatgtc aaacggtttg
     4801 aacaacaagg gaactctctc gttttgacag cggtcgacgg tgaattaaaa gtactgatgg
     4861 gcattcgcga tcaagtccgt ccgggtgtga aagctaattt gcaggaatta aaagacttgg
     4921 gcgtgaaaaa tctagtcgtt ctttcaggag ataaccaagg aaccgttgat gtggtcgccg
     4981 gcgaacttgg tttgaccgaa gctcacggct acatgttgcc ggaagacaaa tcggcttata
     5041 tcggaaaact tcaacaacgt ggtcaaattg tagcctttgt tggagatggc gttaacgata
     5101 gtccgtcctt agctttagca gacattggaa tcgcaatggg aagcggaacg gacgtagcga
     5161 ttgaaacatc cgatgtcgtt ttaatgaact cgaacttcag caacttgcct cacgcattag
     5221 gattagtaaa agccaccgca aataatatga aacaaaatat cgtgatttca attggagtag
     5281 tgttggtctt gttgaccagc gtcttcttca gcgaatggat gaatatgtct atcggaatgt
     5341 tggttcatga aggtagtatc ttggtggtaa ttttcaatgg catgagatta atgaagtata
     5401 agttgaaagg tcgaaaagaa caaaaagaag tatcagcacc tgcagagaaa gtaaaaatat
     5461 cttaagaata aattagaaga ggctgagaca atagtccatc cttgaaatga caaaagcgga
     5521 aactcagatt tttaaatctg ggattttccg cttttttgag ttcttgaaaa aaaataagag
     5581 tatagagtat gttctttata aaattaattt tcgtgtaaat gattaaaaaa tttaataata
     5641 aaatttaaat tcctattaag ttgtaacaca tgaaattgct tataatagtg tattgaaatt
     5701 aaggtagatt gacaaacgag tgatcaaata gatatactac cttcaaacga ccgtttgaat
     5761 gtgaggtgag atgaatggaa aaagtttgcc aagtgactat cgtacataaa gaaaaagtaa
     5821 atgtaataaa aaaaaaattg gatcaaaaag atttttcaaa cttacttgtg ttagggaaat
     5881 gtttcagcga ttcttctagg attaaaattt tctatgcttt agaaacctat aaggaaatgt
     5941 gtgtctgtga tttagcagaa atacttactg ctagtgtcgc tacaacgtca caccatttac
     6001 gttttttaaa aaaacatgga atggcaaaat cacgtcaaga tggaaaagta gtttattatt
     6061 ctttagcgaa tgaagacatc ctttccgcta ttcgtgtttt tttaaagtta tcagaaaatc
     6121 tatctatgaa atcttagttt ggaggaagtt attttgttac aaagtatttt ttcagctatc
     6181 gctgtttata tttctaccag tattgattat ttgtttatct tgctgattat cttttctcaa
     6241 agccacacaa aaaaaggtat tcgtcacatt ttttggggtc aatatcttgg aacaggtatt
     6301 ttggtagccg taagtttgtt tgctgcttat gtgctaaatt ttattccgca agattggatc
     6361 attggtcttc tcggtctaat tccgattttc ttaggaatca gagtcgcttt tgttggcgaa
     6421 gaggaggaag aagaagagga agtcgttgaa aaactcgaat ctagaggaac taatcgctta
     6481 ttctggacag ttgccttaat aacgattgct tctggaggcg ataatttagg tatttatatt
     6541 ccatacttta cctcgttagc tttttcagaa atcattattg ctttaatcgt attcgctatc
     6601 tctgttgcgg ttctctgcta tatcagttac aaattagcca agatttcttt tgtttccgaa
     6661 acgttagaaa aatacgaacg aatcattgtc cctataatgt ttattgcgtt aggaattttt
     6721 attatgatag agaacgggac gatacaaacg ctactaggtt tttaaaaatc ataatcacga
     6781 aagataaaaa gagaggcagc gactaatcaa aatcgctgcc ttttttgctt ttcaaataat
     6841 gaagtatttt ttagcgtaga actatcttac gtgttgtggg agtatccctt ttcaagctct
     6901 tctttgcttg tagttatttc tattgtgata tgattctcta cgcttgattt gtgtgcgact
     6961 tctgcaattt cttcttttat ttccctagcc ttgtctatgt ctgaagggtc tataagaacc
     7021 gtgatgataa gggcgttttc ttccccgtcc agtgaccaaa tgtgaaaatg tgagaggtct
     7081 tttacagcag gaacattttt aatggagtcc gccaagctct ttacgtttac attttcaggc
     7141 gaaccattca ataaaatttt cattgtggtg aaaaattcag gaacggtttt gtagaggata
     7201 taaagtgcaa tcaaaatcga taagatagga tccagacgat atgcctcggt aaagttcatt
     7261 agaatactca caatcaagac tccaatccac cctaatacgt cttccagcat atggaggttc
     7321 aacatgctct cgtttttgga tgtgcctttg cttaaaatcc acgcagcata tccattcaat
     7381 gcaatagcta cgagagaaag ccagaacatg ccactataat ttacgggttg tgggtcaatc
     7441 aaacgtggca cactacgata gatcataaaa aacgagccac taattagcac aacgccagtt
     7501 atcagcgcgc ccagtaaaga aaagcggtta tagccaaaag tgaaccgttc atcttgtttt
     7561 ttctctgaat aaccttgaaa aaaccaagcg aatccaattg aaatagagtc ccctaaatca
     7621 tgaactgcgt cggacataat ggacacacta ttgaaaagaa agccaaagaa aaattcgctt
     7681 atagagaaaa taagatttat gaagaaagca attttaatat tctttttcgg ttgattctga
     7741 ttcgagtgat tatggtcttt atctgatttt gacatttaaa aacctcctaa gtttgtatgc
     7801 tacatactaa ttggttttat ttttctaatt cattaacatg agttaagact tgttcgagaa
     7861 tactaaaaac atgaaggtca tctaaactgt aaagcatact ttttccttct cttcttgatt
     7921 tcactaagcg tgcgtctttc aacgttttta attgatgaga aatagcggac tgttccatgt
     7981 ccagagaaat agcgatattt ccaacactac actctttttt ctgtaaaaga aagagaaccg
     8041 acaatcgtgt aggatcacta atcaccttaa atagtttgct tattgacaga atagatcctt
     8101 tatcgattgg agaagttgtt tttatatcca tagtgttttt attcctttca tatgaccttc
     8161 cgttcatatc tatattacca tatgagcgaa acaatgctaa tcttttgttt ataaaagaga
     8221 agtggcgttc tctttatctt gacaaaatgt atatagcgat ataaaatgag tatacaaaca
     8281 tatgattaat tagtcatatg taaggtggat tcattacgat ttacttttgg aataaacgaa
     8341 aggagtcaga aatagcagaa atttatgtga ttcaagaagt aaatgatgga aaacaaagga
     8401 attataaatt atatagggag gcaatagaag tggaaactat ccaagaacaa cagtctcaag
     8461 aaaagcataa tcataatcac aaccacgatc acgaccatga tcatgggaaa atgccagtcg
     8521 ttttgtactt tgttggttta gcattagcag tgattgctct atttttgaat gaagattatc
     8581 agttggtaca aaatgttttg ttctcaatcg ctacaatcag tgccgggtat cacgttattc
     8641 ttcttgaagg ccttggagaa acaattgaga attcaaaagc acaaaaaaag ttcataccta
     8701 attctcatat tttaatggga ttagcggcaa ttggagcttc tttgatgggg aatttttggg
     8761 aaggaacatt attgattctt attttttctg gcgcacattt tttggaagat tatgcagaag
     8821 gaagaagcaa acgagaaata acgaaattac tcgaaatgaa tccaacgact gcccggttaa
     8881 tcctgcctga tggtagtaca aaaaatgtgg atgtcagtga attaaaagtg ggagatcaac
     8941 ttcaagtgtt gaatggcgat caagtaccta ttgatggcgt cattttgtct ggatctacat
     9001 ccattgatga gtcgtctatt actggagaaa gtatcccgaa agagaaatcc aaaggagatg
     9061 gcgtcttcgg gagtacaatc aatggaacag gtaccttcac gatgaaagtc accaaagaaa
     9121 acaaagatac agtattttca aaaattttac aattagtgaa tcagaaccaa gataaccaaa
     9181 caaaagctgc gagtattatc caaaaatttg aaccgaaata tgtcacagtt gttttaattg
     9241 ccattcctct attcatgtta ttggctcctt ttctacttga ttggacatgg tcacaaagtg
     9301 tctatagagg attggtcctt ttagttgcag cttcaccgtg tgctttagca gcagctactg
     9361 tctcggcaac gctatcgacg acttctaatt tagccaaaaa aggagtcctt tcaaaaggta
     9421 gttcttacct gtctcaatta gccgatatta aagcaattgc atttgataag acgggcacct
     9481 tgaccaaagg aaaacctgaa gtaaccaatt attattttgc tgattccgtg aacgaagaaa
     9541 acatgattga tatcgtagta gctcttgaaa aagaatccaa tcacccctta gcagatgcta
     9601 ttctaagaaa gtttgagcaa aaaaacaaac taactattga agtagaaaac caaattggta
     9661 aaggattgac gggagattac aaagggagaa attatcgtat aggaaaaccg acttcgtttg
     9721 atgatgtttc agatgaatat agtcgtttaa ataatgaatg ggcgtcagaa ggtaagacag
     9781 tcgtatacgt agcagtagat gaagaggtta taggccttat tgcccttatg gacgttccga
     9841 gtgaatatgc taaagaaacc attgaatatt ttaggaaaca aggtatacac accacattaa
     9901 ttactggtga ctcagaaatg acgggaaaag cggttgctaa acaattagga atagatgaag
     9961 tgattgcgaa tgtcatgccg gaagacaaat ccagaattat agacgaacaa aaagaaaaat
    10021 acggcgtgac cgtcatggtt ggagacggtg taaatgatgc tcctgctctt gttaatgcag
    10081 atgtgggaat cgctatggga gatgggactg atgtggcagt agaggtatct gatttagttt
    10141 taatgcaaaa caatttatct aaattggtac aatctcataa tatttcttcg aaaatgaacc
    10201 gtgttatttg gcagaatatt attttttcaa tggccgttgt tgctttttta attgtcgtta
    10261 gtttcttagg cttaacggat attgcaatca gtgtcattat tcatgaagga agtactttgg
    10321 ttgttatttt gaatggactt cgattgctaa aggcagtcta aagaatgatt gcacaacttc
    10381 aaattaatcg agtaatagag ataattaagg attacactac attttttatc tctattactt
    10441 gtttatattt atctagatgt tcaaagtcaa aatgatatat caaccatact cttgtggcgc
    10501 gggttgaata taagatacat gaaattggat aaaatcatgt atcaagaatc ctatccttat
    10561 agggttcttt ttttttactc cccctaaaca cacgatttcg tgttgtaata actataatca
    10621 tgtattcgaa cagactaaaa aggagggatt gtcatgggct ataatgttca gccactacgg
    10681 tcgcaacagg agattaatga ttttttattt tgcctgcgac ggaataaaaa tgcggaacgt
    10741 gacgttttct tgtttctaat tggaattaac agcggtctgc gcatgtccga catcgttaaa
    10801 ctcaagaaaa aagacgtgat tacctcaaaa aacccgcgca tcgtggagca aaagacaggg
    10861 aaaacacgca ttttatactt aagcagctta caggacttga ttcacggcta taccgcaccc
    10921 ttagatccgg aggcttactt gtttcccagt actaagggcg gccatttaga agtcaatacg
    10981 gtctaccaga tgtttcaaaa ggtcgcgaag ctgttaggaa gggacgatat cggcacccac
    11041 accctacgaa aaacctttgg ttaccactat tacaagaaaa ccaaagacgt ggccacctta
    11101 atggaaatct ttggtcacag cagcgagaag attaccaaac gctacatcgg aattaatgaa
    11161 gatgaaatca gtgaaacgtt attaaatttt cggttaggtt tttgattgta ttatataata
    11221 gataagcaca gtaagacggt tataatcacc cacagtattg gacaaatcaa cctttttttg
    11281 gtatattata tatacaaatg agagcaggct catagtcaac ttgatataaa tccggaacat
    11341 aagggtccgg cgggtggcga gcaccaaaac taaactcgat acaaatccgg aacgtaaggg
    11401 tccggcgggt ggcaagcacc aaaactaaac ctgtacaaaa ggctgctctt ttgagcagct
    11461 ttttttattg ggaaaaagga gcattcttcg cacgcggcaa aaaaagaata caaacgcatg
    11521 tctataaaag agacaaccca aattaccaga cagttaaacg cgatttataa ggctgctcat
    11581 ctcttacaag aacattttgt agataaaaaa gtatcctttg tcggagaagt ctcaacggta
    11641 gcgattattt tttcgacaac taattttatg cacctctgtg gcattgatta tcgcagaggc
    11701 acacacttgt tttttcaaga tgccttagac aggaaaataa atttacagga tattcaaatc
    11761 aaaacggatg ggacgacctt tcagaaatta caagtaatag gtagccttga tttattattg
    11821 gggaagcata tttctattgt tggcagaggt gtttactctt ctcttcgcta tgatgcagct
    11881 attcgaacaa ggaaaaaaat attggctctg tctttgaaac aaaacggatt aatctatatc
    11941 cctatctctt tgttaaacct atcatcaaag gaaattggac ctggacaaaa agttactggc
    12001 atttttagcg aggatttaac atccggggaa cttaaaatga ttatggaagt catcgattaa
    12061 tcattaatag tgatatgcga cgtcattttg aagtaattat tctattttgg gttataaaat
    12121 aaagcatttt aagacgattt caaatcattc atgtgggtta tttatcacgg atgagcttga
    12181 aatcgtcttt tatacgtatc aaattgaaat gttcggcata caacctatcg ttgttactac
    12241 attactaatt gtcacttgtt aaggaacttg gatcctttct aaacattccc tagagataaa
    12301 ttttacttta tccctccgtt aatatccaat ttaagcacct ttccgattca gggttaattt
    12361 gcatatcaag tgcagcttgt gttctagtaa gattagccct tttagtccgg ctgagttgac
    12421 ttatggatat aagatatggt catagcaaat agatactacg tatagtctgt taatttagtg
    12481 tcattaatct taagttggat aggctacaat taactagaca gaaaaattaa ggtgtgtaga
    12541 ctagaagaaa acataccagg aggaattttt atgtctaaga gaacacgaag aactttttca
    12601 caagaattca agca
//
LOCUS       DASHXG010000072        12143 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.075, whole genome shotgun sequence.
ACCESSION   DASHXG010000072 DASHXG010000000
VERSION     DASHXG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.075"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..565
                     /locus_tag="U2R59_002416"
     CDS             <1..565
                     /locus_tag="U2R59_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEM8966761.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            966..1571
                     /locus_tag="U2R59_002417"
     CDS             966..1571
                     /locus_tag="U2R59_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HEM8966762.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1587..2159
                     /locus_tag="U2R59_002418"
     CDS             1587..2159
                     /locus_tag="U2R59_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966763.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2411..2668)
                     /locus_tag="U2R59_002419"
     CDS             complement(2411..2668)
                     /locus_tag="U2R59_002419"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966764.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2794..3609)
                     /locus_tag="U2R59_002420"
     CDS             complement(2794..3609)
                     /locus_tag="U2R59_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966765.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4126..5451
                     /locus_tag="U2R59_002421"
     CDS             4126..5451
                     /locus_tag="U2R59_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8966766.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5444..5794
                     /locus_tag="U2R59_002422"
     CDS             5444..5794
                     /locus_tag="U2R59_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966767.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5776..5961
                     /locus_tag="U2R59_002423"
     CDS             5776..5961
                     /locus_tag="U2R59_002423"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966768.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6865..7140)
                     /locus_tag="U2R59_002424"
     CDS             complement(6865..7140)
                     /locus_tag="U2R59_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HEM8966769.1"
                     /translation="MALLPTNKDKKKIGAKDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7112..8065)
                     /locus_tag="U2R59_002425"
     CDS             complement(7112..8065)
                     /locus_tag="U2R59_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8966770.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8677..10170
                     /locus_tag="U2R59_002426"
     CDS             8677..10170
                     /locus_tag="U2R59_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HEM8966771.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10305..10601
                     /locus_tag="U2R59_002427"
     CDS             10305..10601
                     /locus_tag="U2R59_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEM8966772.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10702..11553
                     /locus_tag="U2R59_002428"
     CDS             10702..11553
                     /locus_tag="U2R59_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966773.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11574..11857
                     /locus_tag="U2R59_002429"
                     /pseudo
     CDS             11574..11857
                     /locus_tag="U2R59_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4170 a         1863 c         2268 g         3842 t
ORIGIN      
        1 ttattttaag tctgaaaagg atacatcgtc tctaacgtta actttagagg aaggagttga
       61 acctgacaag gtgacctcta aagtgataaa ccaattgaaa gaaaaaggta gtttgaaaca
      121 tttgggggaa tatgaagtgt tagatacggc tatgttaacg aaaggaattg gtcaaatcct
      181 cagtacgatc acttatttta taacagctgt agcaggtata tctttattta tcgcaggggt
      241 aggtgtaatg aacatgatgt atatatctgt atctgaacga acaaaagaga tcggtataag
      301 aagagcccta ggagctactc gaaaatcgat tatgctgcag ttccttttag aaggtttgat
      361 tttaactctt tcaggagggt taattggcta tttattagga atggctcttg cttatagtgt
      421 tggttctttg ataaaggtaa acgtgtcact tgatctattt actattttac tagcggttgg
      481 ggtatcttcg gttattggac tggtcttttc tgtaatgccc gcttcagagg ctgcaaaaaa
      541 agatttaatt gatattctta gataaaatca gaatgacaag aatatttacg ttctagattc
      601 taaaataaaa cacaaagaga ccaaccaggc accctattgt ttctttgtag tatagagata
      661 ttctttggct tgtaagagat caatagagtt aggtgaccgg agttcgaaat aaaggaaatt
      721 tttgattgta taggagaatt ctttatccct aatatttaga attttgagta tgccatgttg
      781 atgttttaga ttctctataa atatagaggt gtatcaaagg tcaactagac tgtgcaaaat
      841 agagacactt gaaaaatcta tcgggggtca gaaacttaat agtttttgac acataaacaa
      901 aatcgcgata taatggggtt gagagtgttt cataaactta tgtcataaag ttaaggagat
      961 ttcgcatgat tttagagaat aaattgggat taaccaatca agttgagttg gctaaggttg
     1021 aagaaaaact cagtaaacaa aaagcgaaag aattgtacga ttgtggaaaa ataaatgaaa
     1081 tcgaagttgg tacatttaaa ggtttatctg aaattcatga atttctattt tcggatattt
     1141 acgattttgc cggaaaaatc cgatcggtca atattgcaaa aggaaatttt cgatttgcac
     1201 cagttatgta tttagaacat tcgttacagc atattgatca gatgccacaa acttcttttg
     1261 aagagattat caagaaatat gtggagatga atatcgctca cccatttcga gaaggaaatg
     1321 gccgaagtac tagaatttgg ctggatctca ttttaaagga agaattgcaa aaagttgtag
     1381 attggaactt aatcgataaa gcagactatc tttctgcaat ggagcgaagt cccataaacg
     1441 atttggaaat acgctatcta atttccaatg ctctgactga taaaattgac gatcgcgagt
     1501 tatatatgaa aggaatcgat gtcagctatt tctatgaagg gtattctgag tatacgatag
     1561 atgatttgta aaagtaggtg gaccaaatga cgaaatatgg atatgcacgt gtctcaaccg
     1621 cttctcaaag tacaaaagaa caaattcaac agttgcttga gaacggcgta gagaagaaga
     1681 atattttttc agaaaaattt acgggtacaa aacgggatcg gccaaaattc aatcagctgt
     1741 tggctggtct gaagcctgga gatgaaatag ttgttacgaa gcttgatcga tttgctcgta
     1801 acacgagaga agcattagag atcattgaac ctttactcga tgataacgta acgatcaagg
     1861 ttttgaatct aggaacgatt gaaaatacgt ccatggggcg aatggtgaca cggacgttgt
     1921 tgagtgtagc agaaatggaa cgtgatatga ttgtggaacg tacccaagaa ggaaaaatgt
     1981 ttgcaagaaa gaataatcct aatttcagag aaggacgtcc gaaagcaaca atcacaccga
     2041 agaagaggca cgcatatgaa ctgcttactt caggtaaatc gtataaggaa gttgaagcta
     2101 taaccggttt cagtcgcagt acgcttttta gaataaagaa gaaaattgaa gaaagttaaa
     2161 aaagaagtct cagcgaacca gacaggtaaa tacttaatgc gttctagata tgagtctatt
     2221 agcatgttgt gaaatataat atttttttat ttacttgatt tctgctcaaa aaatgtgtat
     2281 ggtaactgta aaaggtaaag taattaaagg tatgctagcc acgcttacta tattaggata
     2341 ccatcatata tttataatga acgatttgtt cgtctaccaa acaacacata tcgttcagcg
     2401 taagtcacgt ttaggaacgt ggctttttta gtgttattat cgataaataa tctattgact
     2461 ctattgattt tatctccata tccctacggt gttgattgtc tttagatctt tcatttaaga
     2521 accaaataac tatcataaaa atcagcactg ctgctaatat aataaacagc attcctattg
     2581 tgatattacc tattgatttt accataacta cgattaaagt aataatggca ttcaagtctc
     2641 ctttgttctc tatatataaa ttagccataa atcatcttcc tttcaaatta agatacttgt
     2701 ttgataccaa taaatagtaa gcgtggctag catacctttt tctgtaatag caagtgttct
     2761 aatagtccaa acttaatgat ggaccgatgc tagttatagt acagtaatgt tttctttctt
     2821 atctagattt ttagtaagct ctatcagcaa atctaacaaa tctgagtcct tttcagaaac
     2881 taaattaaat ctagtgttta caacaaagtt ttcatgttct atattgttta gattatttgc
     2941 ggaaaggagg gcttctagat cttgacattc aaatctatat gcatcgtcat aaatcttact
     3001 agaaggagtg cttaattcga aattacttat tttctcatct tggaccaaga taaatttata
     3061 gatagtatct ttttgtgttt ttcttttaaa aacacaacag agtgtgttat aaggaacgtt
     3121 ataattttca tcagcctcat tttttctcca ttcaaacaaa tgataaactg caaccaagtt
     3181 gccatcaatt tcatggacag tgctctcggt aacatccttt aaagaactat caagggctaa
     3241 tttatagtaa ctagagagag gaagtaaaat tgtcgattta ctgagatggt tatcgtctat
     3301 acgtgcaatc atacctaaat caactaaggt tttattccag gtgtttatag ttttagttgt
     3361 cactcctaga gactctgcta tggtattgac cgaatgccag gaatccccgc cttcattctt
     3421 tgccttaaaa cagtaataca gatataaatt aatagctttg ttattcggta aatatttttc
     3481 aagttctgtt ggtagaataa agtaagaatc cttaatgttt tttctgaact gtctccagtc
     3541 tctgtagttt tgtttataaa gttgtgaaac ggtttttcca cctttagaaa gtcctgctat
     3601 cttaaccaat cttattgctc ctttcttgaa tctgtcatga tcatacagta ttttttactt
     3661 gtagtccagc accttaatat attatcctat gtaattaatt tcgtactaga tagtaattat
     3721 tttttattta attctctagt cacttacaaa taagttatat aaactacgat taataaatta
     3781 ttacaaaaac tattaagaaa acttctacat acaactatta caaaactatt aagaaactga
     3841 atactcctat tttttgtttt taaggaaagt tttttctttt ttgaatttct tatttttttc
     3901 taatataact aagcaaaact ggataatacg acacttattt tcaaattttc acaagactaa
     3961 tagtaaatat ccatttaata aagtgataca atgtgttgat tttacaaatc aacagaagaa
     4021 gtagggaaat aacttaccta tgcttctttt tttgtacatt taatcgattc ttctttacaa
     4081 aaacgaacgt atgtttgtat aatgtggaag aatggagtgt tatttatgat ggattattca
     4141 aaagagccag taaatgatta ctttttgatc gatatgaaaa gcttttacgc aagtgtcgaa
     4201 tgtatagaaa ggaatttaga tccattaacg actgaattag tcgtcatgag tcgagcggat
     4261 aatacaggat cagggttgat tttagcttct tcaccagctg caaagaagaa gtacggtatt
     4321 tctaatgtca gtcgaccacg agatctaccg caaccttttc ctaaaacgtt acatgtcgtt
     4381 ccaccacgca tgaatctcta tattaagcga aatatgcagg taaacaatat tttcagaagg
     4441 tatgtagcag acgaagattt attgatttac tcgatcgatg aatcgatctt aaaagtgacc
     4501 agatcaatga atctttttac gactgaagga acaagaagtc aacggagaaa gaagctggct
     4561 caaatgatcc aggagaatat taaagaagag ctaggattgc ttgctacagt aggtgtcgga
     4621 gataatccct tattagctaa acttgcttta gacaatgaag caaaacataa tgatggattc
     4681 cttgctgaat ggacgtatca aaatgttcct gataaagtat ggaatattcc tgaaatgaca
     4741 gacctttggg gtattggatc tcgaatgaaa aaaagactca accaaattgg tatcatgagt
     4801 attaaagact tagctaattg gaatccatac actattaaga gccatttagg tgtgattggc
     4861 ttacagctgt attttcatgc gaacgggatc gatcgaacag atatagcgat cccaccagaa
     4921 ccgacaaagg aaaaatcata tggtaattca caagtgttac cacgagatta taccaggaga
     4981 aatgaaatcg aactggtggt aaaagaaatg gcggaacaag tagctattcg tatcaggcaa
     5041 cataactgta aaacaggttg tgtccattta tacattggca cgtcgatctt agaaacgaga
     5101 ccaggttttt cacaccagat gaagatccct ataacagata atacaaagga attgcagaat
     5161 tactgtcttt tcttgtttga taagtattat gaaggacaag aagtaaggca cgttggaata
     5221 acctatagca agcttgtgta cactgattcg cttcagctgg atttatttag tgatccacaa
     5281 aagcaaattg acgaagaaaa tttagataaa attattgaca agattcggca aaaatatggt
     5341 tttacgtcga ttgtacatgc ttcttctatg ttagaaggcg ctcgtagtat tactagaagt
     5401 acattggttg gtggccatgc aggcggcgca ggagggctta aaaatgattg attataatga
     5461 tcgtggacgt ttaaagtggg caggttttta tttatctgat catactgaaa aaattgatgc
     5521 cgacaatgaa caacgagcca atcaaaattt ggcaaaagaa caaatgacga ctgaagaggt
     5581 tgcggaagta ttgaacgctg cagtcataaa aaatagatca gtatgtattc aaaaagaaga
     5641 acgaaacgct gaaggatact atccagaaga tattgttagc aagatcttag gtagtgatga
     5701 gctggggatc tacgttggaa aaaacaaagt tcactacgac gaaatacgtc atatcgaatt
     5761 ttaccaggat aataaatggg gtcgattaga atgaacatta tccagcaata tgagctaaag
     5821 tatataacct ttgatcagct atcagaagag atttggggtt atggccagcg tttgataaat
     5881 gaggttggtg ttgaacgctt ctctttctat gtagaagctg cagcaggata ccataaatac
     5941 gaatactata ttggctatta aagtgcaata aaattatatt tcttttatgt tttacatttt
     6001 gtatcaattc tgataaaatt acctataggt aattaaaaaa tataaaaaaa ctagttacaa
     6061 ccttaggacg ttgtaactag cttgaagcat actagagcta actaaaatag cactagaaag
     6121 caatgttaaa cccgtccaac aaacttgatt taacattgag accagcttat tcagctaaat
     6181 atagttgaat aagcttcttt tgttttaaaa aaacaaaagg tgtactacga ataacgcaag
     6241 taaaagaaat actattacaa ccagtaggct acaagtaagt attactaaac attgcgtagt
     6301 tagaaccttt gctctattgt ctaaagccac aaaattagag atcagcttta tgatgctaag
     6361 agcgagctgc atccatgcgg acataggttc ttttgacact attaattctc ctttttagga
     6421 taagggaaat tgctagtagt tttttcatta gcaccatccc ccttcatttg attgagtcta
     6481 gtgctgctgt gatagtttgc tgtttaatat gcttacattc ttattataac ataaatgaaa
     6541 caaacacatg gttagaggtc gtatcaatca aaatagtgtc tcacaaacga tttattactt
     6601 actcctgctg actaacggac tgttcttcag taactgtaac tatatgtttg ttaaaaccac
     6661 cattacctgt agataaaaac caatatattt actatactca ctatattaaa tatatttagt
     6721 atagtaaaaa ctagaaacaa taaaatttgt gaatgttgta tacccccaaa caatacacat
     6781 attttgaagg attaggatta ataaagctaa aaatatagta agtatactaa atatatttac
     6841 tatatctagt atacttacta tattttaatc ttttgatcgt ctattatata taatccgttc
     6901 ctcgtcgttt aaagtatcaa cataggcgtc cattgcaagt ttgactattt catacatagg
     6961 aatatctttt gcataactaa gatcccgaat ggtttttagt acgggaggat ctacttgaac
     7021 tggttttctt tctttcgcag tgtactttcg ttcccctaac tcgacattaa tatcatcttt
     7081 aattgaaata tctttagcac caattttctt cttatctttg ttcgttggta ataatgccat
     7141 ttagtttaat ctcctttcca agaggtagga tatgattggc cattgagtca gcatatttag
     7201 gtgtataatc aaatccttca atatcaccat gttgttcata gtattcaatt ctttcttcta
     7261 attctgtaaa gatgtctgca aaaatagccc accatcttcg atctacataa tcatttaatt
     7321 ggataccatt ctcaccatac atttctaacc gatccgagcc tttaacaatg cttttaaaaa
     7381 tgtttgattc accatactta tcaattgttt tttgatagtt tgcgtgttga gaggaacgtc
     7441 gcactgagaa aagaacaggc aaaattccaa tgatttgaag atgagactct tcaaaattcg
     7501 tgacaatcgg aactaaaact ttattaataa aatcttctgt tccttccatt gcgtaccgtt
     7561 ttaattcttg cattgcaata atataatctg cagcagttaa gaatgcacga accacattat
     7621 ctgttgatgg tgggcagtcg ataaagatat aatcgaaatt ttttctcaat tcttctaaag
     7681 gtttaatgaa ggccaatgat ctcttacgac gatcaggata tttttcggac aagtattcat
     7741 taagttcttc agatccagga gagccagcca taatatataa atgtggactt acttgagtaa
     7801 tacctgaaac ccagtcccct tttttgattg ctgcagacat ggatcgatca aagctagtaa
     7861 tttgatacgt tgatccaatg ttggaagtag tatttctttg ttggtcataa tcaattagca
     7921 acacgtcttt ttcaaaaagt tgactagaaa caatcgctaa taaatcattg tctgtagtct
     7981 taccaatgcc gccttttcta cctgtaagca ttacaacttt tcctagttta tctgatgttt
     8041 taaatgcagt ccgtaagttt tccatagttc cctccaattt cctatactaa atatatttag
     8101 tatacttcat atacttaata tattcgatat atctaatata ctccaaattg ataagaattc
     8161 agactttata aggaatatag tggatatact aaatatattt gctatattca gtatatcaga
     8221 tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt gacaatttag agtgaaaaga
     8281 ggtaaactta attctataga aaccacagat aattcactat ttacaaagta gcaaaagcag
     8341 tggtactctt taaacagaaa aattacataa aaaaaagaga cggaaataat tgattttagc
     8401 agaatcaatt atttctgaat cacatggtta ggacatgtgt tcacgctcgt ctcaagaata
     8461 tgtaagtagc taccaactac ttatattaaa agttgatcgg ataccttttc cgattgcctt
     8521 tattctacca aaaaaaggcg agcaactcaa cagaagaacg tttatttagt gtacttaaat
     8581 taaatattct taaacactga agagagaaca catactatgg ctgagattaa agctaaactg
     8641 tgttctcttt ttgtttgaga aaggacgtta caatcgatgt tgagcgaaat ttattcagct
     8701 attcttaaaa acggcttacg tacatacaaa tatcgaaaca gcaccatgaa acctgcaggt
     8761 catattgatt ccagtaggag tggtgctatc tttgcgtacc gtagcaagca attaatgaat
     8821 gttgggcgtg gtatggtcat tacttcggaa gaagctattt tagagaacga aaagaaacta
     8881 acgcattgga cacctaatac ctatcgcttt ggtacttatg cggatgatta tcgaacagtg
     8941 gttaaaggtc attctgagaa aaacttaagt caaatcaaca catttgtagt tgatatcgat
     9001 tcaaaagaga accatcaagg cgaaattatt ttagcctgtt tagatcaagt gggctacatg
     9061 ccaacgctaa ttttagaatc agatcatggt tatcaagttt attttgtact aaagacacca
     9121 ggctatgtca caaagaaaag caatttcaag gtgatcgatg tagcaaaaaa aatttcaaaa
     9181 acaattcgtc tacagttggc tgaaaaattg tccggagtgg atctaggatg taaccacttc
     9241 ggaattgctc gattcccaca agaaaataat attgttttta aagaaatgaa ctatcagtat
     9301 tcttttgctg actggattca atggtcgatg aagcttgaat cagatcaaaa aacaaaagaa
     9361 gatcgagaac gaaaactaat tgtctttcct gagaaaaaag aaattcgtca agtagatgaa
     9421 ccgtggttcg atatgttact tcataaagca aacatcgtcg gcggagaagg acgtcttggt
     9481 cgaaataatg tgattttcac gctttcttta gcttattact cttcaggtta tgcattggat
     9541 acttgcgaat acaatatgtt cacattcaac gaacggttac aggaaccgct atctgaagca
     9601 gaattagtaa agattgtacg tagtgcttat tctggtaatt atcaagcagc aagcagagaa
     9661 ttcattattg aattgtgcca gcaatgggtt tcaccaacct taaaaaataa tgatctgttc
     9721 attcaacgac gtggctggtg gaaatttaaa aagccacgag atcaaagaaa atatagtcat
     9781 aaaaatgaat ggaaagaaga tctattggct tatctaagcg aaaaaagtct tgctagtgag
     9841 ccttatttga acctgtcaaa aaaagaattg gcttcacaac taacgatgcc caagcgaaca
     9901 cttgataaga tcttaaatga gttacgagag gagaataaag tcttctacaa ggtaacacga
     9961 ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt tgttcgcgag ggttattcaa
    10021 ctaagtaaag aaaagagact agattattca acaaggatca cagaggtatt tggactcaac
    10081 gagagcttag tagaagagac atttagacaa ttatcaaccc ccttgaaccc tcttaaagaa
    10141 gtgaatcttt ttgaagtaga tacaggttga aaaataaaag gtgcaaattg ccttatacaa
    10201 tatatctatg atacttctgt aggtgttgct ccctttgcct agctacgtgt aggtggtata
    10261 cttataactg cgtatgcagt cttatgtatc atggaggaag ttgtatgtcg ttaaaaaatt
    10321 atgtctattc acatcctgtt aatgtgttta tcattggtcg tttgggatta tctgtggaag
    10381 tgttctgtga gctttatggt tttaagcagg ggactttgtc ttcttgggtt accagggaaa
    10441 aaacagttgc ttctttgccg attgagtttc ttcatgggtt gtccttagct tctggggaga
    10501 ctatggatca ggtatatgat tgtttgtgtg tgttagagca ggagtatatt gagtataaaa
    10561 tagctaacga gttaagaaaa aggaagaagt atatccagta gtagttttta tttacttaaa
    10621 aaattggttc attgagcaac ctatcgctgc taaagtagca aaggaaaacg ttaaaggaaa
    10681 gaatttaggg aagaaatcga aatgaaatcg gacgactgga ttgaacacac ctggcttcct
    10741 ctgaaaagaa atagcaaacg aaagaaattt tgggtattgc aattatggcc attaggaaaa
    10801 ctttgtagtt acggggcacg acttattctt gatttaaccg tttactcgat tggagtattt
    10861 ggaacggctt attacttgat aaatgatccc aataggattg cagcatcaga catttttaca
    10921 gtgctaatga cgttgatttt tgtcatgcta ttgtctattt ttactcaatt agtcatgcaa
    10981 tttaccaggc aaaaattaac agcaggaaaa cttttcaaaa gcctattcga tttaattgtt
    11041 gtaaatgcaa ttctagcgac tttaataaaa caaattgaac aatctggaag aacaacaaaa
    11101 ggagtgaagg attttttatt gacgtttatt cactttgtaa atggacacat gtatttgttt
    11161 gaagtgggta ttattctctt ttttgtcggg tatgtatcca cgaaacttat taaacgttca
    11221 attgaaaaag aaattgaaat tgacctgatt ccgacacttc ttggttatga gtacaatgtt
    11281 gattttggaa gatatgacga attgatcaat acggatatcg ttcacacgag tatccatgaa
    11341 tctactgtta agggcatcag atctatttta aaaaatggcc aggaaatgaa agcaatagat
    11401 cgaagaaaag agatctacaa tttttatgaa gtcgaagcaa gcctacgata tggcatcgga
    11461 aaattgtggt tagatggaag taatattcgt caaaacaaac catacatttt ttggaacagt
    11521 agtgatttag aacttccaat gaaagataaa taattatgga gaatcgtttg aaaatgattc
    11581 ctctatacag gattgtgctt atagttggca tggagttaaa aaccttaaag aaggagcagt
    11641 tattcaaagt gaaagaacgt cataatcagt tactatgtag taaaacgggt acgatgaaca
    11701 ttgaataccg aacagaatat ttagaattaa cgaatcaaac tgattttttg ttgattcgaa
    11761 agcaacaaga gcaagaaaaa aattaatggc tacttatagc caattgattg atgaatggga
    11821 acaattcaag gaatctaaaa ttccagaacg tctctaaaag cctttatttg taaagagcat
    11881 aaggaaacgt gggaacactt tttaaaaaaa gtgttccaat aggctgtgcc tattacgttt
    11941 ctcaaaaata aatgtgggaa caaaatattt aaaaatagga tagtgaaagg atagtgaagg
    12001 atagtaaaag gagggtagta ggatagcaaa aaggataggc tccttttcgc tatccttttt
    12061 aaattggagg aattaatatg gaagtaagaa taagaaatgt ggatgagaaa atcgtaagag
    12121 aaattgatcg aagatgtgac gaa
//
LOCUS       DASHXG010000073        11741 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.077, whole genome shotgun sequence.
ACCESSION   DASHXG010000073 DASHXG010000000
VERSION     DASHXG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.077"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..936
                     /locus_tag="U2R59_002430"
     CDS             <1..936
                     /locus_tag="U2R59_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8966774.1"
                     /translation="GRWKETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESL
                     AIDILTFLTGISSRDGERFPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADH
                     IESFTDYDFAHLLFSDGYVEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVA
                     MLIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFV
                     TQNTDDLLDEKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQC
                     LISDLYGRVGVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            939..3122
                     /locus_tag="U2R59_002431"
     CDS             939..3122
                     /locus_tag="U2R59_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8966775.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            3119..4120
                     /locus_tag="U2R59_002432"
     CDS             3119..4120
                     /locus_tag="U2R59_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8966776.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            4135..5049
                     /locus_tag="U2R59_002433"
     CDS             4135..5049
                     /locus_tag="U2R59_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8966777.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5294..5410
                     /locus_tag="U2R59_002434"
     CDS             5294..5410
                     /locus_tag="U2R59_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEM8966778.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            5426..7345
                     /gene="tet(M)"
                     /locus_tag="U2R59_002435"
     CDS             5426..7345
                     /gene="tet(M)"
                     /locus_tag="U2R59_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEM8966779.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQREVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            7443..8816
                     /gene="tet(L)"
                     /locus_tag="U2R59_002436"
     CDS             7443..8816
                     /gene="tet(L)"
                     /locus_tag="U2R59_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HEM8966780.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            9380..10642
                     /locus_tag="U2R59_002437"
     CDS             9380..10642
                     /locus_tag="U2R59_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEM8966781.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            10887..>11741
                     /locus_tag="U2R59_002438"
     CDS             10887..>11741
                     /locus_tag="U2R59_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEM8966782.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKK"
BASE COUNT         3901 a         1945 c         2451 g         3444 t
ORIGIN      
        1 ggcagatgga aagaaacctt gccagagatt tcccatgaaa tcaatatcgt caatctgact
       61 tctgatgaga aaaacaaagg cttacttgac ccttatgtaa ttatgaaaaa taccaaagat
      121 tctgaatcac tggctattga tattttgaca ttccttacgg ggatttcctc tcgtgatggg
      181 gaacgcttcc caatccttag aaaagccatt cgtgcagtaa ccaatagtga agtgcgaggg
      241 ttgatgaaag tgattgaaga attacgggtt gagaatacgc cactaagtac cagcatagcc
      301 gaccatatcg aaagttttac agactatgac tttgcccatc tgctttttag tgatggttat
      361 gtagagcagt ctatcagcct tgaaaaacaa ctgaacatta tacaggttgc cgacttggta
      421 cttcctgaca aggaaacttc ctttgaggaa tataccacaa tggagttact atcggtagca
      481 atgctgattg tcattagtac ctttgcgttg gactttatcc atacagaccg aagtattttc
      541 aagattgtag acttagacga agcatggagc ttcttacagg tggcacaagg gaaaacacta
      601 tctatgaagc tggttcgtgc tggtcgtgct atgaacgctg gggtatattt cgtgacccaa
      661 aatacagatg acctcttaga tgaaaaactg aaaaataacc tcggcttaaa atttgccttt
      721 cgttccactg accttaacga gattaaaaaa acccttgcct tttttggtgt agacccagag
      781 gacgaaaaca atcagaagcg attgcgtgat ttggaaaacg ggcaatgcct tatcagtgat
      841 ttatatggtc gtgtcggtgt gatacagttc caccctgtat ttgaagaact gctccatgcc
      901 tttgatacca gaccacctgt gcgaaaagag gtgtaaatgt gaaaccatca atattaaaca
      961 gaataaaatc aaactggacg ctgaaacgtc taggtaaagt ggcaatgaca gtggctttca
     1021 cacttgtgat tgccattttt cttttagcca tgctgggaac ggtggttcaa gctgcgggct
     1081 tggtagatga tacggtcaat gtggcaaatg aatacagccg atacccactt gaaaactatc
     1141 aactggattt ttatgtggat aatagctggg gctggctacc gtggaactgg tcggacggaa
     1201 ttggaaaaca agtcatgtat ggactatatg ccattaccaa ttttatttgg acaatcagtc
     1261 tttatgtttc caatgcgacg ggttacttag tacaggaagc ctattcctta gacttcattt
     1321 ccgctacagc agattccatt ggcaagaata tgcagaccct tgcaggggtt acgcctagtg
     1381 gactatcaac agagggtttc tatgttggat tccttttact cttgattttg gttcttgggg
     1441 tttatgttgc ctatacagga ctgataaaga gagaaaccac aaaggcaatt catgccctca
     1501 tgaattttgt gctggttttt atcctatcgg cttcctttat tgcctacgct cccgactaca
     1561 ttaaaaaaat caatgacttt tcatcagaca tcagcaacgc tagtttgtca ctgggtacaa
     1621 aaattgtcat gccccattca gatagtcaag gcaaggacag tgtggacttg atacgtgaca
     1681 gcctattttc catacaggtt cagcaaccgt ggctactgct tcaatataac agttcagaca
     1741 ttgaaagtat tggtattgac cgtgtggaaa gcctgctctc aaccagtcca gattccaaca
     1801 atggggaaga cagagaaaaa attgttgcgg aagaaattga agatagaagc aataccaata
     1861 tgacgattac aaagacgatt aaccgtttag gtacagtctt cttcctattt gtcttcaata
     1921 ttgggatttc catatttgta ttcctattaa caggaatcat gattttctcg caggtacttt
     1981 ttatcatcta tgctatgttt ctgcctgtga gctttatttt aagcatgatt ccatcatttg
     2041 atggtatgtc aaaacgagcc ataacaaagc tctttaatac cattttgaca cgagctggaa
     2101 tcacattgat tattacgaca gcatttagta tttcaaccat gctctatacc ttatcggctg
     2161 gttatccgtt ctttttgatt gcttttctac agattgtgac ctttgcagga atctacttta
     2221 agctgggcga tttaatgagt atgttttctc tacagagtaa cgattctcaa agtgtgggaa
     2281 gtcgtatgat gagaaaacct cgtatgctta tgcacgctca catgcaccgt ctacagcgga
     2341 aacttggacg ctccgtgact gctttagggg ctgggtctgc cattgccagt gctacgggta
     2401 aaaaaggaca gtcgggttcg ggaagttctg cgagtacaca agcagatcac tctcgaccaa
     2461 acgggcagga aaaatcaaca ctaggaaagc gtatcggtca aaccatcggt acagtagctg
     2521 ataccaaaga cagaatggta gatactgctg gtaatttgaa agaacaggtt aaggatttgc
     2581 cgaccaatgc aagatatgca gtatatcaag gaaaatctaa agtgacggat aatgtccatg
     2641 atttaaccag aagtatttct caaaccaaag cggataaagc cagtggacgc aagaaacagc
     2701 aggaacaaag acggaaaacc attgcggagc gtcgctctga aatggaacag gtcaaacaga
     2761 aaaaacagcc agcttcttcc gttcatgaaa gaccagccac taagcaagaa caatctcatg
     2821 atggacagac ttcaaggcaa acaactgtac aggcttccta tagggaatct caacaagcca
     2881 aacaagagcg tccaacagtt aagtccgatt cttcaagttt aaaaacggaa cgtcaaagta
     2941 atacagttca agaaagaacg gttcaaaagc cagtaacttc aactgcacca acagatagag
     3001 cttcacaacg ttcaatcaca aaagaacgtc agtctactgt tcaaagagta ccactacaaa
     3061 atacaaaaag tagaccacca atcaaaaccg ccaccattaa gaaaggcagt aagaaaccat
     3121 gaagctgaaa actttagtga ttggtggttc gggattattc ttgatggtct tctcactgct
     3181 tctgtttgtc gccattttat tttcagatga acaagatggc ggtttttcca acattcacta
     3241 tggcggtgtg gatgtttccg cagaagtgct ggctcataag cctatggtag aaaaagttgc
     3301 caaagaatat ggaattgaag aatacgtcaa tatacttctt gcgattatac aggtggaatc
     3361 gggtggtaca gcagaagatg ttatgcagtc ctcggaatcc ctcggtcttc cacctaattc
     3421 attgagtaca gaagaatcca ttaagcaagg tgtgaagtat ttcagtgagt tattagccag
     3481 tagcgaaagg cttggtgtag atttagaatc ggttatccag tcctacaatt atggtggtgg
     3541 tttcttagga tatgtggcta atcgtgggaa taaatatacc tttgaactgg ctcaaagttt
     3601 ctcaaaagag tattcgggtg acgaaaaagt gtcttacccc aatcccatag ccatacctat
     3661 caatgggggc tggcgataca attacgggaa tatgttttat gtgcaactgg taacgcagta
     3721 tcttgtcaca acagagtttg atgatgatac agtacaagcc atcatggacg aagctctgaa
     3781 atttgaaggc tggaagtatg tctatggcgg agcttccccg actacctctt ttgattgtag
     3841 cggactgaca caatggacgt atggaaaagc tggaatcaac ttaccacgaa cagcacaaca
     3901 gcaatatgat gtaacccggc atatcccatt attggaagca aaagccggcg atttggtttt
     3961 ctttcattct acctataacg ctggctctta tattactcat atcgggattt atttaggcga
     4021 taaccgtatg tttcatgcag gcgaccctat cggttatgcc gacttaacaa gctcttactg
     4081 gcaacagcat ttagtgggag caggacgaat caaacaataa gaaaggacga ttcaatgatg
     4141 aaattcggaa aaaatcagaa tacagaaaaa cagacaccaa aggaaaagaa acctcgtgtc
     4201 tataaggtca atcctcgtaa aaaggttgtg attgtcctat gggtactttt aggacttagt
     4261 ttcagctttg cgatattcaa gcactttaca gccattgata cccataccat tcatgaaacc
     4321 accatcatag aaaaggaata tgtcgatact catcatgtgg aaaattttgt agagaacttt
     4381 gcgaaagtct actattcatg ggaactaaac gacaagtcca ttgataatcg catagaaaac
     4441 ctgaaagcat atctgacaga ggaacttcaa gctctgaatg tcgatacagt tcgtaaagat
     4501 attcctgtat cgtcttctgt aaaaggattt cagatatgga cggtagaagc agatggcgac
     4561 aatcaatttg atgtaaccta cagtgtagac caactcatta cagaggggga aaatacaaag
     4621 accgtccact ctgcttatat agtgagtgtc tatgtagaca gtactggaaa tatggtcctc
     4681 attaagaatc cgaccattac tagcatacca aagaaatcag actataaacc aaaagctatt
     4741 gaaagtgagg gtacggttga ttccattaca accaatgaaa tcaatgagtt tttaacgacg
     4801 ttcttcaagc tctatcctac agcgacagcc agtgaacttt cctactatgt gaatgacggg
     4861 atattaaaac caatcggaaa agagtacatc tttcaagaac tggtaaatcc tatttacaat
     4921 cgtaaggata atcaagtcac ggtatcgctg acagtggagt atatcgacca gcagaccaaa
     4981 gcaacgcagg tatctcaatt tgatttggta cttgaaaaga acgggagtaa ttggaagatt
     5041 atagaataac aaatattggt acattattac agctattttg taatcacgta ctctctttga
     5101 taaaaaattg gagattcctt tacaaatatg ctcttacgtg ctattattta agtatctatt
     5161 taaaaggagt taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagtg
     5221 ggaacaaata attggatgtc cttttttagg agggcttagt tttttgcacc cagtttaaga
     5281 atacctttat catgtgattc taaagtatcc ggagaatatc tgtatgcttt gtatgcctat
     5341 ggttatgcat aaaaatccca gtgataagag tatttatcac tgggattttt atgccctttt
     5401 gggcttttga atggaggaaa atcacatgaa aattattaat attggagttt tagctcatgt
     5461 tgatgcggga aaaactacct taacagaaag cttattatat aacagtggag cgattacaga
     5521 attaggaagc gtggacaaag gtacaacgag gacggataat acgcttttag aacgtcagag
     5581 aggaattaca attcagacag gaataacctc ttttcagtgg gaaaatacga aggtgaacat
     5641 catagacacg ccaggacata tggatttctt agcagaagta tatcgttcat tatcagtttt
     5701 agatggggca attctactga tttctgcaaa agatggcgta caagcacaaa ctcgtatatt
     5761 atttcatgca cttaggaaaa tggggattcc cacaatcttt tttatcaata agattgacca
     5821 aaatggaatt gatttatcaa cggtttatca ggatattaaa gagaaacttt ctgccgaaat
     5881 tgtaatcaaa cagaaggtag aactgtatcc taatatgtgt gtgacgaact ttaccgaatc
     5941 tgaacaatgg gatacggtaa tagagggaaa cgatgacctt ttagagaaat atatgtccgg
     6001 taaatcatta gaagcattgg aactcgaaca agaggaaagc ataagatttc agaattgctc
     6061 cttgtaccct gtttatcatg gaagcgcaaa aagcaacata gggattgagc agcttataga
     6121 agtgataacg aataaatttt attcatcaac atacagaaag aagtctgaac tttgcggaaa
     6181 tgtcttcaaa attgaatatt cggaagaaag acaacgtctt gcatatgtac gcctttatgg
     6241 cggaatcctg catttgcggg attcggttag aatatcggaa aaggaaaaaa taaaaattac
     6301 agaaatgtat acttcaataa atggtgaatt atgtaaaatt gataaggctt attccgggga
     6361 aattgttatt ttgcaaaatg agtttttgaa gctaaatagt gttcttggag atacaaagct
     6421 attgccacag agagagagaa ttgaaaatcc gctccctctg ctgcaaacaa ctgttgaacc
     6481 gagcaaacct caacaaaggg aaatgttact tgatgcactt ttagaaatct ccgacagtga
     6541 cccgcttcta caatattatg tggattctac gacacatgaa attatacttt ctttcttagg
     6601 gaaagtacaa agggaagtga ttagtgcact gttgcaagaa aagtatcatg tggagataga
     6661 actaaaagag cctacagtca tttatatgga gagaccgtta aaaaatgcag aatataccat
     6721 tcacatcgaa gtgccgccaa atcctttctg ggcttccatt ggtttatctg tatcaccgct
     6781 tccgttggga agtggaatgc agtatgagag ctcggtttct cttggatact taaatcaatc
     6841 atttcaaaat gcagttatgg aagggatacg ctatggttgc gaacaaggat tatatggttg
     6901 gaatgtgacg gattgtaaaa tctgttttaa gtatggctta tactatagcc ctgttagtac
     6961 cccagcagat tttcggatgc ttgctcctat tgtattggaa caagtcttaa aaaaagctgg
     7021 aacagaattg ttagagccat atcttagttt taaaatttat gcgccacagg aatatctttc
     7081 acgagcatac aacgatgctc ctaaatattg tgcgaacatc gtagacactc aattgaaaaa
     7141 taatgaggtc attcttagtg gagaaatccc tgctcggtgt attcaagaat atcgtagtga
     7201 tttaactttc tttacaaatg gacgtagtgt ttgtttaaca gagttaaaag ggtaccatgt
     7261 tactaccggt gaacctgttt gccagccccg tcgtccaaat agtcggatag ataaagtacg
     7321 atatatgttc aataaaataa cttagtgtat tttatgttgt tatataaata tggtttcttg
     7381 ttaaataaga tgaaatattt tttaataaag atttgaatta aagtgtaaag gaggaattaa
     7441 ttatgaagtg taatgaatgt aacagggtta aatacaacca aattttaatt tggctttgcg
     7501 ttttatcttt ttttagcgta ttaaatgaaa tggttttgaa cgtctcatta cctgatattg
     7561 caaatgattt taataaacca cctgcgagta caaactgggt gaacacagcc tttatgttaa
     7621 ccttttccat tggaacagct gtatatggaa agctatctga tcaattaggc atcaaaaggt
     7681 tactcctatt tggaattata ataaattgtt tcgggtcggt aattgggttt gttggccatt
     7741 ctttcttttc cttacttatt atggctcgtt ttattcaagg ggctggtgca gctgcatttc
     7801 cagcactcgt aatggttgta gttgcgcgct atattccaaa ggaaaatagg ggtaaagcat
     7861 ttggtcttat tggatcgata gtagccatgg gagaaggagt cggtccagcg attggtggaa
     7921 tgatagccca ttatattcat tggtcctatc ttctactcat tcctatgata acaattatca
     7981 ctgttccgtt tcttatgaaa ttattaaaga aagaagtaag gataaaaggt cattttgata
     8041 tcaaaggaat tatactaatg tctgtaggca ttgtattttt tatgttgttt acaacatcat
     8101 atagcatttc ttttcttatc gttagcgtgc tgtcattcct gatatttgta aaacatatca
     8161 ggaaagtaac agatcctttt gttgatcccg gattagggaa aaatatacct tttatgattg
     8221 gagttctttg tgggggaatt atatttggaa cagtagcagg gtttgtctct atggttcctt
     8281 atatgatgaa agatgttcac cagctaagta ctgccgaaat cggaagtgta attattttcc
     8341 ctggaacaat gagtgtcatt attttcggct acattggtgg gatacttgtt gatagaagag
     8401 gtcctttata cgtgttaaac atcggagtta catttctttc tgttagcttt ttaactgctt
     8461 cctttctttt agaaacaaca tcatggttca tgacaattat aatcgtattt gttttaggtg
     8521 ggctttcgtt caccaaaaca gttatatcaa caattgtttc aagtagcttg aaacagcagg
     8581 aagctggtgc tggaatgagt ttgcttaact ttaccagctt tttatcagag ggaacaggta
     8641 ttgcaattgt aggtggttta ttatccatac ccttacttga tcaaaggttg ttacctatgg
     8701 aagttgatca gtcaacttat ctgtatagta atttgttatt acttttttca ggaatcattg
     8761 tcattagttg gctggttacc ttgaatgtat ataaacattc tcaaagggat ttctaaatcg
     8821 ttaagggatc aactttggga gagagttcaa aattgatcct ttttttataa caggaattca
     8881 aatctttttg ttccattaaa gggcgcgatt gctgaataaa agatacgaga gacctctctt
     8941 gtatcttttt tattttgagt ggttttgtcc gttacactag aaaaccgaaa gacaataaaa
     9001 attttattct tgctgagtct ggctttcggt aagctagaca aaacggacaa aataaaaatt
     9061 ggcaagggtt taaaggtgga gattttttga gtgatcttct caaaaaatac tacctgtccc
     9121 ttgctgattt ttaaacgagc acgagagcaa aacccccctt tgctgaggtg gcagagggca
     9181 ggtttttttg tttctttttt ctcgtaaaaa aaagaaaggt cttaaaggtt ttatggtttt
     9241 ggtcggcact gccgacagcc tcgcagagca cacactttat gaatataaag tatagtgtgt
     9301 tatactttac ttggaagtgg ttgccggaaa gagcgaaaat gcctcacatt tgtgccacct
     9361 aaaaaggagc gatttacata tgagttatgc agtttgtaga atgcaaaaag tgaaatcagc
     9421 tggactaaaa ggcatgcaat ttcataatca aagagagcga aaaagtagaa cgaatgatga
     9481 tattgaccat gagcgaacac gtgaaaatta tgatttgaaa aatgataaaa atattgatta
     9541 caacgaacgt gtcaaagaaa ttattgaatc acaaaaaaca ggtacaagaa aaacgaggaa
     9601 agatgctgtt cttgtaaatg agttgctagt aacatctgac cgagattttt ttgagcaact
     9661 ggatccagga gaacaaaaac gattttttga ggaaagttat aaattatttt ccgaacgata
     9721 tggcaagcaa aatattgctt atgcaacagt tcataatgat gagcaaaccc ctcacatgca
     9781 tttaggtgtt gtgcctatgc gtgatggaaa actgcaagga aaaaatgtgt ttaatcgtca
     9841 agaactgtta tggctacaag ataaattccc cgagcatatg aaaaaacagg gttttgagtt
     9901 gaagcgtggt gaacgtggct ctgaccgtaa acatattgag acagctaaat ttaaaaaaca
     9961 aactttggaa aaagagattg attttctaga aaaaaattta gcagttaaaa aagatgaatg
    10021 gactgcttat agcgataaag ttaaatcaga tttagaagta ccagcgaaac gacacatgaa
    10081 aagtgttgaa gtgccaacgg gtgaaaagtc catgtttggt ttgggaaaag aaataatgaa
    10141 aacagaaaag aaaccaacca aaaatgttgt tatatcggag cgtgattata aaaacttagt
    10201 gactgctgcg agagataacg ataggttaaa acagcatgtt agaaatctca tgagtactga
    10261 tatggcgaga gaatataaaa aattaagtaa agaacatggg caagttaaag aaaaatatag
    10321 tggtcttgta gagcgattta atgaaaatgt aaatgattat aatgagttgc ttgaagaaaa
    10381 caagtcttta aagtctaaaa taagcgattt aaagcgtgat gtgagtttaa tctatgaaag
    10441 cactaaggaa ttccttaagg aacgtacaga cggcttaaaa gcctttaaaa acgtttttaa
    10501 ggggtttgta gacaaggtaa aggataaaac agcacaattc caagaaaaac acgatttaga
    10561 acctaaaaag aacgaatttg aactaactca taaccgagag gtaaaaaaag aacgaagtcg
    10621 agatcaggga atgagtttat aaaataaaaa aagcacctga aaaggtgtct ttttttgatg
    10681 gttttgaact tgttctttct tatcttgata tatatagaaa taacgtcatt tttattttag
    10741 ttgctgaaag gtgcgttgaa gtgttggtat gtatgtgttt taaagtattg aaaaccctta
    10801 aaattggttg cacagaaaaa ccccatctgt taaagttata agtgaccaaa caaataacta
    10861 aatagatggg ggtttctttt aatattatgt gtcctaatag tagcatttat tcagatgaaa
    10921 aatcaagggt tttagtggac aagacaaaaa gtggaaaagt gagaccatgg agagaaaaga
    10981 aaatcgctaa tgttgattac tttgaacttc tgcatattct tgaatttaaa aaggctgaaa
    11041 gagtaaaaga ttgtgctgaa atattagagt ataaacaaaa tcgtgaaaca ggcgaaagaa
    11101 agttgtatcg agtgtggttt tgtaaatcca ggctttgtcc aatgtgcaac tggaggagag
    11161 caatgaaaca tggcattcag tcacaaaagg ttgttgctga agttattaaa caaaagccaa
    11221 cagttcgttg gttgtttctc acattaacag ttaaaaatgt ttatgatggc gaagaattaa
    11281 ataagagttt gtcagatatg gctcaaagat ttcgccgaat gatgcaatat aaaaaaatta
    11341 ataaaaatct tgttggtttt atgcgtgcaa cggaagtgac aataaataat aaagataatt
    11401 cttataatca gcacatgcat gtattggtat gtgtggaacc aacttatttt aagaatacag
    11461 aaaactacgt gaatcaaaaa caatggattc aattttggaa aaaggcaatg aaattagact
    11521 atgatccaaa tgtaaaagtt caaatgattc gaccgaaaaa taaatataaa tcggatatac
    11581 aatcggcaat tgacgaaact gcaaaatatc ctgtaaagga tacggatttt atgaccgatg
    11641 atgaagaaaa gaatttgaaa cgtttgtctg atttggagga aggtttacac cgtaaaaggt
    11701 taatctccta tggtggtttg ttaaaagaaa tacataaaaa a
//
LOCUS       DASHXG010000074        11352 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.078, whole genome shotgun sequence.
ACCESSION   DASHXG010000074 DASHXG010000000
VERSION     DASHXG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.078"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            287..694
                     /locus_tag="U2R59_002439"
     CDS             287..694
                     /locus_tag="U2R59_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966783.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="U2R59_002440"
     CDS             708..1109
                     /locus_tag="U2R59_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966784.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="U2R59_002441"
     CDS             1111..1482
                     /locus_tag="U2R59_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966785.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1817)
                     /locus_tag="U2R59_002442"
     CDS             complement(1518..1817)
                     /locus_tag="U2R59_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966786.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1823..2053)
                     /locus_tag="U2R59_002443"
     CDS             complement(1823..2053)
                     /locus_tag="U2R59_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966787.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            2670..3332
                     /locus_tag="U2R59_002444"
     CDS             2670..3332
                     /locus_tag="U2R59_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966788.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            3411..6638
                     /gene="fss3"
                     /locus_tag="U2R59_002445"
     CDS             3411..6638
                     /gene="fss3"
                     /locus_tag="U2R59_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HEM8966789.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            6752..7066
                     /locus_tag="U2R59_002446"
     CDS             6752..7066
                     /locus_tag="U2R59_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8966790.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            7079..7453
                     /locus_tag="U2R59_002447"
     CDS             7079..7453
                     /locus_tag="U2R59_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEM8966791.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            7463..7807
                     /locus_tag="U2R59_002448"
     CDS             7463..7807
                     /locus_tag="U2R59_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEM8966792.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            7878..9230
                     /locus_tag="U2R59_002449"
     CDS             7878..9230
                     /locus_tag="U2R59_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEM8966793.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            9290..10432
                     /locus_tag="U2R59_002450"
     CDS             9290..10432
                     /locus_tag="U2R59_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEM8966794.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            10457..10711
                     /locus_tag="U2R59_002451"
     CDS             10457..10711
                     /locus_tag="U2R59_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966795.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            10967..>11352
                     /locus_tag="U2R59_002452"
     CDS             10967..>11352
                     /locus_tag="U2R59_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966796.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGV"
BASE COUNT         3867 a         1871 c         2408 g         3206 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc
     1741 cacaccttat aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgc
     1801 gtctcattaa aaagcataac cattactccg atctattttt aaacttagtc tctacctcta
     1861 atatatatcg agtttttatt ttgccttcag agaatactgt ttcttttttt gcagttacag
     1921 gttgtttatt ttcggaaaaa gctaatatag ctaaaattga aacatccatc tggaatttat
     1981 cttttttact gctttgatca taaaagtctg catattcatc actgatattt tttctaataa
     2041 attcttccat cataaaaatc acctcaaaac gattatacga acttacgttc ttgttgtaaa
     2101 gcgatatttg aggggcaaaa agggggcaaa aatgcgttta cctttgatat atctcagatt
     2161 gaacatagtg tttattttat gtcggtattg ttgatttata gctgttttga gggtgttaga
     2221 tacataatag aatatagtgg ttttgtttac gtgcattaca cggaaaagct gctcgtatca
     2281 aagaaatcag aagataaaca cggaaaactt ccttggaaat ctgaaatttg tgaaaagtcc
     2341 ttgtatatca agggcttttt cttttttctc tatcacagtt ttaagccatt tttggctgtt
     2401 ttggaccatt tttcaatcat attcccttaa aaattgtcct agattgtccg acattgacta
     2461 tcagtgtcgt caaaataggg caaaatttag tagtcagctt gacgacaaat ataatacgaa
     2521 aaataccaaa acatttaccg aatttagcaa cttttgaacc caagtttctc aaagggtcag
     2581 ctattagcaa aaaagacaaa acatgtactt ttctactaaa aagttgatgt gataggcttc
     2641 tatctaaata actattagga gtttttatcg tgaagcaaaa tgatggacgt atcatttgga
     2701 aaaatcaaag tgagttaaaa ctgattttaa caattaatga attcatcgaa aaacacggaa
     2761 ttacatctag ccgtcaatac cagaaaaagc tatcagaaaa tccaaattct gcaccaagta
     2821 tgtggttcat taacaaaaaa tatggatcat gggagaattt attgattagt ataggacgag
     2881 aaaatactgg gtatggaaaa tgggctagaa tgtcagaaca agaattattg gaaatagtag
     2941 aagcctttat taagtgcgag aagataacct ctcaacgaat gtacgaacaa aaatcagtag
     3001 ggaagaatat tccttcactt agtaccatta aaaagatgtt aggagatata cgtccacttt
     3061 ttaaagaaaa aaatgatgga tctcgattta ctgatttcga actgctgtta gaactaaaaa
     3121 atgaaataat ccgattaaaa ctacaggatg atttatcaat gacaaagttt cgaaaactag
     3181 ttcaatcccc aaaactacca tcagttgata caattatgaa aagaacgaac aaaaattggg
     3241 aggaattgat ggcagagatt ggatttgatt atcgaagaat caaaatttat aagcagagaa
     3301 acaacctatc caagacaaag aaaactaaat agtatcactc taaatcagac gttcaaaatt
     3361 aaaatttgga cgtctttttt attacccaaa aacgaaagga gatttatttt atgaaaaagc
     3421 caagatttaa gaattggcgt ttgctcgcaa cactgagtct attatgccaa acaattggtg
     3481 gatcgcttgg cccaacgatt gcctttgctg atgaaattac tcatccacaa acggtaactg
     3541 tggaattgga tttggctcac cagtatgctg tcgaaggtac atttagcgat ggtcgtccca
     3601 tgtcagaagt taccgttccg cactatgcag tttacaatgg tgtgaagcaa gatattttct
     3661 gtattgagcc aggggtgccg atttacaatg agttcactcc tggttatgag aaaaatccat
     3721 tgcctgatat gtcggagaaa gcgaaattag tttccgtttt atggaaggaa gctggtacgg
     3781 atgtggatac acatattgtg gcccagaaga tgatttggca agaagttaat ggctacacgc
     3841 ttcactcaat taaacgttct gatggtagtg cagtaaatat cgcagccatt gagtcaaaaa
     3901 tcaatcaagc cattgcggat tatcaaaaga aaccaagctt ccataactcc acagtgaaaa
     3961 ccgtgttagg tcaatcgact actgtgacag atacgaacgg cttgaattta tcggagtttg
     4021 atgaagttgt cgagaatatc gcaaatattg attatcgtgt gaacggcaat caactagtga
     4081 ttactccaaa tgccaattca aaagagagtg gtgaattaac cctaaagaag tcagctaata
     4141 caggaacacc ggtagcttat aaaatggctg gtcaacaaac tttgatggcg ggggcaattg
     4201 ataagcccaa tacctacaca atcaaaattg atgtggaaac tgagggttct ttgaagatta
     4261 aaaaagtcga taaagaaaca ggaaatgttg taccgggaac cgttttccat ttagactttg
     4321 gaaaaacatt acctgcaaaa gacgtgacca ccgataaaga aggcattgcg acattggatg
     4381 agattcctca tggcgcgaaa gtaaccatta ctgaaaaatc agtgccagct ccttatacga
     4441 ttgacactac accaatcacc gcaaccatta aatctggtga gactatttct gtgacttcaa
     4501 aaaatactcg cgaaaaaggt caaatcattt tgaataaaat gggggtggaa acaggaactg
     4561 atctttggaa cgacaaatac tcattagccg gaaatacgtt tgccattcgc aaagacagtc
     4621 caaccggtga aattgtccaa gaaatgacca cggatgaaaa aggtcatgcg gaaacaccaa
     4681 aagagattgc caatgcgttg gaattgggaa cctattatgt gaccgaaacc aaagctagta
     4741 atggctttgt gaataccttt aaaccagtaa aagtcgaatt gaactatgtc aatcaaaccg
     4801 tggctcttgt taccagtaac gtaaaagggc aaaaccaaga aatcactggt gaaaccactt
     4861 tgacaaaaga agacaaagat accggtaatg aaactcaagg taaagctgag tttaaaggag
     4921 ctgaatatac tctctttact gcaaaagatg gtcaagcggt caaatggagt gaggctttta
     4981 aaccagagtt agtgaaggga acgaaagctt ctgatgaaac ggtgactttg actttagatg
     5041 aaaagaatca agttgctgtt aaacacttag cgattaatga gtattactgg caagaaacca
     5101 aagcacctga aggatatacc ttggatgaaa caaagtaccc tgtttccatc aaaaaggtgg
     5161 atgataacga aaaaaatgcc gtgattaccc gagatgttac ggcaaaagaa caagtcattc
     5221 gctttggctt tgatttcttt aaatttgctg gatcagctgc tgggactgcc gaaactggct
     5281 tcaatgatct gacctttaaa gtatcgccat tggaaggaac cagtgagatt acaggtgccg
     5341 aagatgaagc aattacagct tataacgagc aactaggttt tgatggctat ggcaagtttg
     5401 aaaatcttcc ttatggggat tatttacttg aagaagtaga ggctccagaa ggatttcaaa
     5461 aaattacgcc attagaaatc cgttctactt ttaaagaaaa taaagcggat tacactaaga
     5521 gtgaatacat ttttacgatt accgaaaaag gacaaaaaca accaattaaa acggtgaccg
     5581 ttccttacga gaaactgacg aataaagcat tttctgttag cttgaatcgt ttgatgctct
     5641 atgatttacc tgaagaagaa gatagcttaa cttctcttgg gacttggaaa gacggaggca
     5701 aagaattgac agaccttgat tctaccgagc tagttgataa attgagctat aacttgcatg
     5761 aaatcaaaga agactggtat gtggtagcgc aagccattga tgtggaagcg acaaaagctg
     5821 cccaagaaaa agatgaaaaa gccaaaccag tggtaattgc cgaaacaacc gcaacgttgg
     5881 cgaataaaga gaaaacagga acttggaaaa ttttgcataa attaaccgca gaacaagttt
     5941 tggataaaac catcgtctta ttcaactatg tgtatgaaaa caagaaaccc tatgaagcag
     6001 gtgatgatcc agtagcgaaa gatgctagct tgaacaatca agcccaaact gtcaattgta
     6061 cggtggaacg ccatgtttcc atccaaacaa aagcccacct agaagatggt tcgcaaacct
     6121 ttactcatgg ggatgtggtg gatatgttcg atgatgtgtc gattacccat gatgtactgg
     6181 atggctcaaa agaagctttt gaaacaattc tgtatgcatt acttccggat aatacgacca
     6241 aagaaatttg gaaatctggc aaaattgatt atgaagtgaa tgacaaagaa ttcactaaaa
     6301 ccgtacttgc ggaaaaagtg gacacaagta aatatccaga aggtacaagt tttaccttca
     6361 aagaaattaa ctatggcaaa gacggaaaca tcaatgggaa acacaatgag gatctaaaag
     6421 aaaaaactca aactttaaca cctaaaaaag ttccgacaac accaagtgca ccagaacaac
     6481 cggaaatacc aactgttcca agtgactctc aagaatctag tcctacagta aagacattcc
     6541 cacaaacagg ggagaaaaat tctaatgttc tgctgtttat tgggtttacc ttgatctttg
     6601 cgactgctgg gtattatttc tggaatcgcc gaaactaagg tgatgtgatg aaacaactaa
     6661 ataggaaaaa ccaacgtgcg cgaccgcctc ctaaaaaaag tggtcgcgct atttttgtat
     6721 ccaaaactaa aaatgaaaag aggaaaagaa gatggaattg aaatttgttg tgccagatat
     6781 ggccgaaacc tttggaaaga taaggtatgc cggcgaaggc gaagttttaa ctgaaggata
     6841 tgggcggaat actacagtaa ttggtcgtag ttatcatttg tattccagta agcaacgagc
     6901 cgatgatatt gaagtggtgg tagctgcgga agccggcgaa aaggattttg atcaagatca
     6961 accactaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg agaatcgtgg
     7021 gtttaccgac tacgtgttgt atgtcgatga tttagtgaaa gcataggagg aaaagaagat
     7081 gagattaaca gaaggtattg ttgtagattc aggactaacg tttgggaaat tacgattttc
     7141 cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acggttagta acgaggtaaa
     7201 agaacggact tataatttga aatcctctgc gcaaggtcga atgatccaag ttagtatccc
     7261 agcaaatgta cccttacgcg agtttgccta tgacgcagag gtagagttgg tcaatccaat
     7321 catggatacg gtcgccaatt atgttttccg agaaggaact actgtcaatt ggttcattaa
     7381 ggccgatgat ttagtcttga aacgacaacc agatcaggga aattctacaa accaaaatga
     7441 aggaaagaaa taggtgaagc gtatggaaat taatgttgaa catattttag attgtctcga
     7501 tcaatatgga aaaggtgagc taacggagga acaactcact aaagcattaa cctatgatga
     7561 aaaaatgttt ctgattatgc atcaagggtt actggaagta ggtaacgatg tcgaagaaga
     7621 ttttgatgta ctgaattggt taggggaaga agagtccttc tttatggtta tcgaagtaaa
     7681 tgaaagtcta tgtcgagaag ccgaaaccgt attggaagaa attggtgtgg aaatgccgga
     7741 tgccattgaa gtttttttaa agcaactagt ggaaacgaaa caactcccta tagcagtaaa
     7801 tgactagcat aactgcttga aattggatca atgaaatcct atgaagcttt tttcgattgg
     7861 aggtggaaac cataaaaatg tacaaagggc atcgtatacg ggcaggagat cagcacttgg
     7921 tttatcactt tgttcttggc tggctactcg ctctgttcat cggttggatg agcgtctttt
     7981 attttcaaga gcttagacaa tttgatattt ctaagctatc actttctact atagaaatcg
     8041 ttcgttctat aaaagattta atctatttgc taggaagtct cgttctttca ggaagcacga
     8101 tgttgcttta tatacacttt tttcaggatc attggcgcag tttgtggcat cgacaaaagc
     8161 tagcccggat gattctagaa aatcattggt acgaagtaaa acaaactcag agtgaaggat
     8221 ttttcaaaga cctcaatagt agtcgaacca aagagacaat cagttacttc cccaaaatct
     8281 attaccgtat gaaggatggt ttactttcta ttcgcgttca aatttcactg ggaaaatatc
     8341 aagatcagct tttaaagctg gaaaagaagt tagaaagtgg tctatattgt gaactagtag
     8401 aaaaggaact caaagactcc tatgtggagt acactttact gtatgatata attgccaatc
     8461 gaattgggat agacgaagta gtggcagaaa gtggggcttt gcgattgatg aaaaatcaag
     8521 tatgggctta tgattcttta cctcatatgt taatcgctgg cggcacaggt ggtgggaaga
     8581 cttacttttt actcactatc atcgaggctt tattaaaatc tgatgccgag ctttttgttc
     8641 ttgatcccaa aaatgcggac ttagccgatt taggtacggt aatgcctcat gtctattccc
     8701 aaaaggagga aatttctgct tgtgtggaag atttctatga gcgcatgatg actcgtagca
     8761 aggcaatgaa agaaatgccc aactacaaaa caggagagaa ttatgcgttt cttggacttc
     8821 caccaaactt tttaatcttt gatgaatacg tggtttatat ggaaatgtta acgacgaagg
     8881 aaagtgcggt gattttgaat aagctcaaac aaatcgtgat gttaggtcgt caatctggtt
     8941 tctttctgat tctagcttgt caaagaccgg atgcgaaata tttaggagac gggattcgcg
     9001 atcaatttaa tttccgggtg gctttgggtc gtatgagtga actgggatat tccatgatgt
     9061 ttggcgaggt tgataaaaaa ttctttatga agcgtatcaa aggtcgaggc tatgtagata
     9121 cgggagggag tgtgattagt gagttttata cgccacttgt accaaaagga tatgatttct
     9181 taagggaaat tagcgacatt ggtggattaa acgttaatac ggaaggataa aataatagta
     9241 tgtagcctag gagtgtcaag aatcctgggc tttttttacg aggtgattta tgacattttt
     9301 agatttattc gctgggattg gtggcttttg cttaggtatg gaacaagcgg gtcaccagtg
     9361 tatcggcttt tgtgaaattg atgattttgc tcgccagagt tataaggcaa tccatgatac
     9421 aagtaaggag gtggaaatgc atgacatcac aagtgtatca gacgagttta ttcaatctct
     9481 cggaccagtg gatatccttt gcggtggatt tccgtgccaa gctttttcaa ttgcgggaaa
     9541 gcggcaagga ttttccgata ctcgaggtac tttattcttt gaaatcgctc ggttcgccgc
     9601 tattctccaa cctaagtttt tattccttga gaacgtccgg ggattactca atcacgaagg
     9661 aggggctacg ttcgagacga tcctccgaac gctggatgga ttggggtatg atgtggaatg
     9721 gcaagtgctt aactcaaagg cctacgttcc ccaaaaccgt gagcggatct tccttatcgg
     9781 acattctcga gacgcatgta ccgaacaagt atttcctatc attggatcgt ctccaacatc
     9841 tgatcaaaac atcagaaact tattaaatat caacccttcc aatcgaggaa tggggggaca
     9901 agtctatggg tcagatgacg tagcgcctac cttgaccggt gatgaaggaa tcaaaatcgc
     9961 attgccggta gatgatggaa tttctgtagc gggtatgtta ctgggaaatt ttgaacaagg
    10021 caatcgggtt tatgagataa ctggaacagc gcctactttg tcaacgaaac aaggcggaac
    10081 gaagatcatg cttcggaaaa acgaaacaga atatcaagag gtgaagccag ggaacagtgt
    10141 gaacctggct tttcctaatt ccacaagtcg tcgaggccgt ctgggaaaac aaagtgtgca
    10201 taccttatta acaggagacc aacaagcagt cgtcacggat cagtatcaaa ttcgaaagtt
    10261 aacacctagg gagtgctggc ggcttcaggg ctttccggac tgggcttttg atcgagcttc
    10321 tcaagtcaat tcagatagtc agttgtataa gcaggctgga aattctgtaa cagttccggt
    10381 catttttgat attgctagaa gattaaagga ggtaaaaaca gatgatttat gatgagttga
    10441 ttggggaatc tactgggtga ttggcaagat tcagtcagat ccggaattgg aagaagaact
    10501 gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccctgatg atccgtatgt
    10561 aattgatgag gaaacggatg ctcgaatgga gctgaatcaa gtcatcagtg aattggaacg
    10621 aattgcggac tttgctaaag aacctgatat ccgccaatac ttgtttgaga taaaagcaga
    10681 gttggaaatt gagggtatta ccgcggagta acggccaaat aaaccactga taggcactga
    10741 ccgcggggga tttgcgaagc agaaatcctc cgtggtgctg tgcctgttta tggacggcgt
    10801 tagccggcca tgatgtctca ccccccgtat ctaacagggg ggtacaaaaa cacaaaaaat
    10861 aagcaagcaa cgataaggaa tggctgtcct atcaaggata ataagcaatt tgtgtagatg
    10921 ttaactgatt tgaaaaagtt aacaccttaa atttggaggt gagaacttgg cacaaaggaa
    10981 tttagattat cggctattaa aagaccggcg taatgaatat ggcgtttcac aaaataaatt
    11041 agctacgact tgtggactta gtcgcccgta cttaaatcag atagaaaatg gtggcgtaac
    11101 cgcatcgaca aaaaccatga ggaaaatttt tgaccaactg gaaagtttca atcccgagtt
    11161 acctttaacg ttactgtttg actatgtaag gattcgcttt cccacaacgg atgcgaggaa
    11221 aatcattcaa gagattctcc atttgaaatt tgattatatg ctccacgaag attacgcctt
    11281 ttactcctat caagaacaat atgttatggg agatattgtg gtgatgttgt cacatgaaga
    11341 agataaaggc gt
//
LOCUS       DASHXG010000075        11194 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.079, whole genome shotgun sequence.
ACCESSION   DASHXG010000075 DASHXG010000000
VERSION     DASHXG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.079"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            149..1552
                     /locus_tag="U2R59_002453"
     CDS             149..1552
                     /locus_tag="U2R59_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HEM8966797.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            1901..2533
                     /locus_tag="U2R59_002454"
     CDS             1901..2533
                     /locus_tag="U2R59_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HEM8966798.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3121..4560
                     /locus_tag="U2R59_002455"
     CDS             3121..4560
                     /locus_tag="U2R59_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8966799.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4855..5073
                     /locus_tag="U2R59_002456"
                     /pseudo
     CDS             4855..5073
                     /locus_tag="U2R59_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5322..5537
                     /locus_tag="U2R59_002457"
     CDS             5322..5537
                     /locus_tag="U2R59_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966800.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5754..6010)
                     /locus_tag="U2R59_002458"
                     /pseudo
     CDS             complement(5754..6010)
                     /locus_tag="U2R59_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6197..7108)
                     /locus_tag="U2R59_002459"
     CDS             complement(6197..7108)
                     /locus_tag="U2R59_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8966801.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7127..8131)
                     /locus_tag="U2R59_002460"
     CDS             complement(7127..8131)
                     /locus_tag="U2R59_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8966802.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8128..10251)
                     /locus_tag="U2R59_002461"
     CDS             complement(8128..10251)
                     /locus_tag="U2R59_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8966803.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10256..11176)
                     /locus_tag="U2R59_002462"
     CDS             complement(10256..11176)
                     /locus_tag="U2R59_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8966804.1"
                     /translation="MPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLY
                     GRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         3471 a         2104 c         2083 g         3536 t
ORIGIN      
        1 tttaaaggca gtaacaggat taaacattga aacataatcg ttactaaatg aaatcaagaa
       61 atatactgta ttactcaatt cattgaaaat atttatcata atttttaata gaaaacacta
      121 ttaaagagaa aaaagagagg taaatcaaat gaaaaaatct ttaaaacttg catcagcagt
      181 tatattaatg tcccaactcc ttatagcaac acctttccat gtgttggcaa gcgaaaattc
      241 aacatacaaa attgcaaaag aaagaaccga gacgactgaa atgagtaatt ccgatgtaac
      301 agcagagagt agtgaacttt tgacaacttc atcaagtgaa agtagtacga cttcaaatgc
      361 cgagtcttca acaacttcat caagtgaaag tagtacgact tcaaatgccg agtcttcaac
      421 aacttcgtca agtgaaagta gtacgatttc aagtaccgaa tcttcaacaa cttcaagtag
      481 tacaagtgaa ataacttctt cgaaagtgac aaaaccaaac catatagaat cttcaaaaaa
      541 ggaagcgcca aaaacggaag gacaaacaaa aactttttcg acaccacagc aaatagaatc
      601 aacagaatct ttccaatcac aaccaatact atctggtaat gaagaaattc attttgacaa
      661 aaatgaatct gtagaaaatt ttattatgaa aattggtgag tctgcgagaa aaattggtca
      721 gaaatatgat ttatatgctt ctgttatgat tgcacaagcg atcttagaat ctgccagtgg
      781 tcaaagccag ttagctcagg caccgaatta caatttattt gggataaaag gaacttataa
      841 tggaaacttt gtcattatgg taacaaacga agatttgggt aatggaacgc tttatacgac
      901 ccaatcaaaa tttagagtgt atgaaaacta tgaggaaagc tttgaagatt atgccaaatt
      961 attaactaag ggaattagtg gaaataaaga tttttatgca ggagcattaa aagctaatag
     1021 taaaacatat cgagaagcaa ctaaattcct tacaggacgg tatgcaacag atacacaata
     1081 ctatttgaag ctaaatgaat taattaaaac ctacgattta accaactatg ataaagaagt
     1141 taaaggtcca caaatgagta agactggata ccaagtgcct attcataatt attcaataac
     1201 cagtttgttt ggaaatcgtg gaaatgaatt tcaccgagga cttgatatgg cagctacaca
     1261 gggtgagccg attcatgcag ttaaagctgg taaggttgtt aaagcagagt ttcactactc
     1321 ttggggaaat tacgtggtga tacaacacga agatggatca accgcgttat atgctcacca
     1381 gcaacaatac ctagtaaaaa ctggagataa tgttttgcaa ggacaaataa ttggctatgt
     1441 aggaagtact gggaatagta ctggcccaca ccttcatttg gaaatttgca aagatagtag
     1501 tctttctcag agcatgttag ttgatccgaa aaccttatta ttcggagact aaaaaaggta
     1561 atcaatctga caaagtaaca agaaaatggt tggattctta gacctttgat caggatattg
     1621 agactggaat tgatatctcg attacgatgg gtttgacaaa taaaacaagt ccattatcga
     1681 atatcgagtg tattattgcc gtctttatgc tcatattttg agcaggtttc actagatgaa
     1741 aacaatttat ctatcttgag gatttcgtgt acgtatcgtt cagtcttgta ttgtaaatta
     1801 gtcataaaat cagactaaga aaaattggaa atattttttt ctgatttatt aaaagttaat
     1861 tgaaattata tggtacttct ttcttgggag ggtaggtgca gtgaaggaaa gatatggtca
     1921 ccttactgtt gttgaggaga ttactcataa tggatataaa aaatatcgtt gcctatgtga
     1981 ctgtgggaat gaaacgattg tatatcgatc aaacttacta acaggtagaa ccaaaagttg
     2041 tggatgtgga aattataaaa ataggcataa atataaaaat ttgacaaata aaacttttgg
     2101 taagttagtt gcaatcaagc caactaaact gcgaagtgaa ggaactgttg tttgggaatg
     2161 tcaatgtctg tgtgggagaa aaaagttagt atcggcaaag cgacttctaa aaggtgatgt
     2221 aaaaagctgt ggatgtttga aatcaaaaaa gcatcacatt gaaaataaaa aattcggatt
     2281 acttactgca aagtatcctt tggacaataa ctgttcatgg aaaacaaaat gggtttgtca
     2341 ttgtgagtgt ggcagtatgt gtgagataag ttatagtaac ttattttttg gacatactca
     2401 aagttgtgga tgtttaaaaa ggcaagaaac aaggacatgt gttgaaggga cagtaataga
     2461 gtgtctaacg tcaaaattac cgaaaaataa tacaagtggt gttaagggag tttatcgttc
     2521 taaagagaaa tagattgcgt atataacttt aaaaaaaaag aggtactatt taggatcgta
     2581 tgattctatt aagagtgcag ctcaagctag aaaagatgct gaaaataaat tgtttcaacc
     2641 tttgattgac aaatatcgag gtaatcatta attattgtgg ataataatta acagtgatat
     2701 ataaacatct ataatatatt attcatacta ttgatattta gtataatcct atggaattga
     2761 atatcatagc aatgtatttg aaaagcaaat tggaaaacaa ataggtgcaa caccataaat
     2821 atgaaaaaat tgggaaaaag tagaatggaa atttgcttac gtctcacgag atagctcaca
     2881 ctattaatct gaagaacaat gaagtcgact tttagaaatt gctagaagaa agtaaagcga
     2941 attatcacta gttactatag agtaagttca aataaagcat ctccaactta catggttaca
     3001 tgaggatatc aaatcgaaat tactcaagct tcctatggct agagtcgcga gaagttgttg
     3061 ggcagtagac ataggttata ttgttcttag ctacacgatc attagaaagg aaatcctatt
     3121 atgtatagtt atcaagaaga tgcaaaagtc caaaaaaatc gctggtggat tttgattgct
     3181 atatctatgt ttaccttcat gtccacattg gatggcagta ttgtcaatat tgcactacct
     3241 accatctcag atgatatggg cataccaatg aatcaagcgg aatgggtagt gtccgtttat
     3301 ctgatgattg tctgttcttg tttgttgctg tttggtaaaa ttggcgatag ccgtgggaaa
     3361 atcaaagtat ttcggattgg tacgctgatc tttgtcttgg gatcgctgtt gtgtgggttc
     3421 aatcattcgc taggtatttt attgttcgca cgggtggtac aagccattgg tgctagtatg
     3481 actatggcta caaatgccgg aatcatcacg gaagtctttc ccatacatga acgtggtcgg
     3541 gcattgggag caataggtgc gtttgtttca ttaggctcga ttgctggacc aggtcttggc
     3601 ggcttgattt tgtcccaatt ttcttgggcg tacatttttt ggatcaatgt accggtggga
     3661 atcgtaacga tgttgattgc tgaaaaattc ttaccaaaag atatcaccat gagcggccat
     3721 acaatcgatg gagggggctt tgctgccatt gcggctacga ttatcagctt ttttggagca
     3781 atctttttgg ggcaagaaag tggctttttc catccagtcc cccttgtact gttcgtaatt
     3841 tcagtgattg cctttgtcag ctttttaaaa gttgaaaaga aagcagcctc tccattgatt
     3901 tctttcggta tttttaagaa caagattttt accatgagct tgattacagc cttgttgatt
     3961 ttttcttcca acttctttgt caatgtagtg attccttttt atctgcaaaa tgctcgcggg
     4021 ttgagtccta gctatgctgg gctgttgatg atggtctttc ctttgatgat ggtcgtcggg
     4081 gcgcctttaa gcggctacct gaccgaccgg gttggcccgg agattttggt attagtaggc
     4141 ttgggcttat tgtcggtaac ccaggtcatg tatatgtttt tgtcagtgga ctctcctttg
     4201 tggctataca ttgtcgctac tgccatcatg ggtgccggca atgccttgtt ccagtccccc
     4261 aataatacga tggttatgag ctcggtcact atcgaaaact tgggactggc aggctcgatg
     4321 aattcctttg cccgaaattt ggggatggtc agcgggattt cgctttctac gacggtctta
     4381 tatcaagcga tgtctgctaa gatgggccag caagtaacta actatatcgc aaatcggccg
     4441 gatgtctttt tatatggaat gaagattacc tttttaggca gctttgtttt gtgttttgtt
     4501 gcctttttcc tgactatctg gcgtatcaaa aaacaaggag gtattcagaa aaatgtctga
     4561 aaaaaccact gttgaagaat ttttggaggc ctgcgtatgg gtgagtggga tttccatgga
     4621 tgatggaaga tgaagtgaac ttctaaaagc cgaaaaactc aagtattatc ttcaaaatac
     4681 tagtgctcaa tgagatgctt gatttgatca caagaagact gcgaaagccg ctggcaaccg
     4741 caagctaggt atcccaccga tggactacgt tttagaggct actggttatg aatacggagc
     4801 caacgctctc atctgcataa gaatacatca cccagattat gtaaagattt tcgatacttc
     4861 tgtcaaaaaa tcattaagat agataaatga tttccgtcta gtcaaattgg ttcagaatgt
     4921 agacacacag atggtaagaa gtcactcaca attcgagaat ggacttgtcc tatttgccgt
     4981 atacatcata atcgaaacgt caacgatagt atcaatattt tgaccaaggg ctatgaatac
     5041 aagcattgcc ttagaaaaca tcaagaacct taggaacaac ggggatagct tggttaataa
     5101 gagataccgc tgtttaggct tgcaagtata ctcttttatc aagaattccg tggctttagt
     5161 catgagaggc ttaatactat gaaaattttc tttagcattt ttgatttagg ttccttttct
     5221 aattataata agatgaccac tacagtaacc tactgaaata tataaacagc cactgtagta
     5281 ccattttcaa agtagtctat gagaggagaa tcttcattct tatgaacgct ggaattgcgg
     5341 atatgaattt aataaaaaaa acccttaatg attttacttc caattcaata tcaaaaggta
     5401 ctggtatcaa tttaagcaca ataaaaaagc tgaaaagtgg tgaaagatca gtggaaaagc
     5461 tgaatctttt agatgctata aaaataacgg aatttgctat gaaaaatgga aaagctgaga
     5521 ttgaaatatg gagataatta tcgtctagtg aattacttgc cacttagctg aatttaacga
     5581 tccttggtgc ttgaaggggg agattcttgg gaatagagca tacttgcaag cctatgtctt
     5641 tactaacaac gatatctctt attaaccaag ctatccccgt agttctaagg cttttacttt
     5701 tatctaagca ataatcgtat tcaaaggaaa tttttgaccc ttagaaagtc tcattttatc
     5761 agacgtgagc ttaggcattg ctgaattttg ttaattcggt tttaggttgt gctttgagca
     5821 taatatgaaa gtattcttta tcacgatttc attcatctaa ggtaatgtga tgtgattctg
     5881 aaattctttc aaaggcagtt tttgcataag ctgacattac atcatcaatg acatgtttac
     5941 aatgtttcac tactaaaata agggggtaac caagaagaaa aactgaatga ttatttgtat
     6001 ctaattccat ggtatatcaa ccatttccta tatagactga ttatgacatg gattaaaata
     6061 aaaaggcact atgtcttaat tgtcggtttt cgagttaccg aatggcattc atcacccacc
     6121 tatagaggat gggcgacttc tgcctgaaat aagttacact acttataact tctaataaaa
     6181 ttagattgag tcattattat ttaacatcaa cgattttcca gtttccattt ttttgtaata
     6241 ctaatttgta ctgaaagtag ctagtggttt ttgatacatt atcaaggtat tttatctttg
     6301 tactcactag aaaatttttt ccgttttgta gataaactgg attctctaac tccgaaaact
     6361 ttaagtcaat attgattggt cgcatcgcac cattttcaac ataatactcc aattcttttt
     6421 cagaagctga tggataaagt ttaaaaaatg tttctaaaaa atcggtgatt tcttccgttg
     6481 ttttggcatc aatttctgaa tcgttttcta cttgttttgc ttcatatttt gccttgtctg
     6541 gctttccaat cattgttggc aaactagtta ctaaatgatt cctgttttca tcttcaaaga
     6601 ttgtcactcg atatgcagaa gaaattgatt gcgtcttttt tccctctgta atatgttgct
     6661 ccactaaaaa tgaaacgaca aattcttccg agtgtttttc aacatctaga atttttacag
     6721 attgaacttc ggaactcgtg ggaatatctg ctcgaaccat atcttggatt aaagcgagac
     6781 cgttttctgt aaggtactgt tcgagattac tcattctctt ttcaattgct tctttgttat
     6841 ttttccatga aaaatattct ttcgcaaaat cctctgtaaa actttcaacg ccagaagtat
     6901 tcactacctt ctcttttata accacttttt catgagttgt atgttgatca atggcggtga
     6961 aatttttata aacgccaaaa gcaagactac aagacaataa aagccaaagg gcaagcacca
     7021 tttttcgatg cttacccacg gatacaactc gttctttttt cttttttggg ctcttttcct
     7081 tttgattccg ttcaattttt atcttcattc tttttcctct tttctcttat ttgtatcggc
     7141 cagctccgat aagatgctgc cgccaatagt tttccgttag attcgtccac cccactggat
     7201 ctcctgcatg aaacatgcga ttctcccctg cgtaaatgcc cacatgggtc acataagtac
     7261 cggcatcata ggttgaatga aagaaaacta aatcacctgg tttggcatct tttagatcaa
     7321 tatgagtcat ggcatcatat tgatcctgag ccacccgagg aagtttcagg tcaactttgg
     7381 cataacacca ttgggtcaag ccactacaat caaaccccgt ttctggactt gagccaccaa
     7441 acacataggc cgttccttca tacttaaatg cctcatcaaa aatttcttgg actattttgt
     7501 catcaaactg agttgtagtt aggtattgct tcactaataa acagtaaaac atattgccat
     7561 aattataccg ccacccacca ttttccttaa tcgcgattgg gttggggtaa tcgacttttt
     7621 gaccacctga tttttccttt gaaaaagatt cagctaaagc aaaactatgc ttcttcccgt
     7681 ttttcccgac atgatctaga tacccgccac catagttata ggcctgaata atactatctt
     7741 gatcacaccc tagttctttg gaacgcttaa ccaaagacgc aaaatagaga cagccttgtt
     7801 tgatggatgc ctcggtactt aatgaattag gtggtaatcc ggctgactca gaactttgca
     7861 taacgtcttc cattgtgcca ccagattcca cttgaataat cgccaaaaga attggaatat
     7921 actctgttat atccgattct ttggcatact tttccaccat tgcacggtgt ttcaatactt
     7981 cttctgagac actagttccg ccaggagaag tgccagaact accatttccc tcactgtctt
     8041 caccaaacaa caaacccaca cacatcaaaa tacccataaa agagatggtc agaaaagtta
     8101 atgaaataac acccactttc ttcaagttca ttttttctca cctgaccttg attttggacg
     8161 atggttcatt cttttttgta ctttttgatt ggtctgcttt ggcagagtgg acctctgttt
     8221 cacttgttgg aaagaatttt tcttacttgc tgattggctt ttcccttttg aaatgatttc
     8281 ttgactagtt agttttcgtt tgatttcggg attcagattt gctctcacaa tccgctttgg
     8341 tgcttctttt ttcagcatca tatctttctg aggttgagct gctttatcta ttggaatatt
     8401 cgcccttctt tttccctgac gatttgttgc ttcactcagt atcttgcgtt tttcgtccat
     8461 tttcgcattt cttcgttgtc gttgtttttc tcgcaaatcc actcgatccg ctttttcttg
     8521 gaacagtccg cgcttgaatt cttctggtgc ttttttcgac ttttcgattc ctttatggag
     8581 attgtatttc aaattcgttg gcgtattcct tacctgatcc tttacttgtt tagtcttatc
     8641 tttcaccaaa gcttgggtat ccaaaacttt gccgattttt ctcccagcca aattcattcg
     8701 ggattgtttc ttattatttg aaactggatt ctccttagtt aagtcagata gtatttcgtg
     8761 atcgttcggt aatcgtgaat tctttcgtag agaagaaccg gatggcttaa atttggattt
     8821 tgattgttcc tttgccaact tatttccgac tgctgcacca ccaccaaaag ccaaagctcg
     8881 tcccacattt cgattgagtt gccgcaattt tcgattcatt aacatttgcg gttttcgcat
     8941 gacgcgtctt cccattgact ggctatcatt actctggagg ttgaacatac tcataatgtc
     9001 gcccaatttg aaatagatac cggcaaaggt cacaatttgc agaaaagcaa ccatgaaaaa
     9061 tggataggtt gccgaaatat tgaaaaacat cgtggagatg ctaaatgcag tcgtaatcac
     9121 caaagtaaca cccgctcgca tcataatcgt attgaataaa cgaataatcg ccttctttcc
     9181 taaactttca taagtcggca acatggacaa taagaaacta attggcagaa acatcgcaaa
     9241 gataatgaag agaatttgcg agaacaacat aatccctgtt agaagaaaaa caaagaagga
     9301 aatgccaata ttgaacaata ccaaaaagac cacggtccct aaacggttca tggtcttggt
     9361 aatactgaga ttcgcattgt cattgtcttc aatctctgcc ttgaccgctt cttcccgatc
     9421 tttgcctttg ttttcatctg gactcacaga tagaatcttg ttgacccggt cttcaccaat
     9481 ttcttctatg ttggaatcat caaattgcag tagtaaccaa ggttgttgga cttgaatcga
     9541 aaacaaacta tcccgaatca aatccacact atcttttcct tggctttctg aattgggtac
     9601 aacgatctcg gttccaaggg taagggccgc ttcactaaca tctgagctaa agtcattgat
     9661 ttttgtgata taggtaggcg cataagcaat gaacgaaccc gatagtagaa aaatcatcac
     9721 aaaattaatc acggctcgaa ctgctttcgt ggtttctcgt tttaataatc cggtatacgc
     9781 cacatacacc cccagagcta aaatcatcaa taatagaaac ccaaaataaa atccggaggt
     9841 ctggagtcca ttttcagtaa taccagccaa tgtttggata ttctttccaa tactttcagc
     9901 cgtatccgaa atgaaatcta atttgtaagc ctcttgaacc acataacccg tggcgttcga
     9961 caaatacaaa ctcaccgtcc aaatgaaatt agtaatggca taaagaccat acatcacgct
    10021 tttccctaag ccatcacccc aattccaagg caaccaatcc caagagctat ccacaaagaa
    10081 atctagttga tagttgttca gtgaatattt ggaatataga tttcctgctt caactgtatc
    10141 atcaactagc cctgtcgcct cggctaccgt accaactaaa ctcaatagaa ctatcagagt
    10201 gagtatgcta ataaaaacga ttcccacaat ccgaaaaagt ttctttttca tcccctcact
    10261 ccattctctc ttgaacaggt ggacgggtat caaaggcatg gaagagttct tcaaagactg
    10321 gatgtacctg aaccacgcct acccgaccat acaaatcctg catcaagcat tggccatttt
    10381 ccaaatctcg taggcgtttt tgattgcttt catcttctcg atccaagcca aagaattcca
    10441 aggttttctt gatttcatga atatcggtac tgcgaaacgc aaacttcaac ccgatattat
    10501 tcttcaagcg ttcatccagt aaatcatcac tattttgcgt gacaaagtaa accccggcat
    10561 tcatagcccg cccagcacga acgagcttat tcgataatgt tttcccttgc gctacttgaa
    10621 gaaaactcca cgcctcatct aagtctacaa ttttgaagat ttctcgatta ctatggataa
    10681 agtccaaggc aaaagtggaa atgacgatta gcatggaaac actaagcaat tccatggtgg
    10741 tatattcttc aaaagtggtt tctgcatctg gtaaaaccaa atccgctact tgaatgatat
    10801 ttaactgcct atctaaacta atcgactggg taatcgaacc atctgagaaa agcaaatggg
    10861 caaaatcata atcggtaaag gactcgatgt gatccgcgat attttccgca actggtgagc
    10921 cttcttttcg aagctcatta attacttgta ataatccccg ttgattgctt tgggtaaccg
    10981 tccgaatggc cttacgcaac actggaaact tctccccatc tcgactagaa attcctgtta
    11041 aaaaggtcag aatatcaatt gctagacttt cagaatcctt ctttttctcc ataatcacat
    11101 aaggatcaag taatccttga ttttttggct tactagttaa gttgagaata ttgatttcat
    11161 ccgcaatttc tggcaaggtt tctttccagc cacc
//
LOCUS       DASHXG010000076        10525 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.080, whole genome shotgun sequence.
ACCESSION   DASHXG010000076 DASHXG010000000
VERSION     DASHXG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.080"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..190)
                     /locus_tag="U2R59_002463"
     CDS             complement(<1..190)
                     /locus_tag="U2R59_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966805.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="U2R59_002464"
     CDS             complement(200..1015)
                     /locus_tag="U2R59_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEM8966806.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="U2R59_002465"
     CDS             complement(1277..1720)
                     /locus_tag="U2R59_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HEM8966807.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="U2R59_002466"
     CDS             complement(1854..2192)
                     /locus_tag="U2R59_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8966808.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="U2R59_002467"
     CDS             complement(2180..2557)
                     /locus_tag="U2R59_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEM8966809.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="U2R59_002468"
     CDS             2781..3974
                     /locus_tag="U2R59_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8966810.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="U2R59_002469"
     CDS             complement(4140..4562)
                     /locus_tag="U2R59_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966811.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="U2R59_002470"
     CDS             4957..5151
                     /locus_tag="U2R59_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966812.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="U2R59_002471"
     CDS             5148..5594
                     /locus_tag="U2R59_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966813.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="U2R59_002472"
     CDS             complement(5804..6976)
                     /locus_tag="U2R59_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEM8966814.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="U2R59_002473"
     CDS             complement(7182..7997)
                     /locus_tag="U2R59_002473"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEM8966815.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="U2R59_002474"
     CDS             complement(8147..8593)
                     /locus_tag="U2R59_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEM8966816.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="U2R59_002475"
     CDS             complement(8590..9594)
                     /locus_tag="U2R59_002475"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEM8966817.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="U2R59_002476"
     CDS             complement(9634..9963)
                     /locus_tag="U2R59_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HEM8966818.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..10349)
                     /locus_tag="U2R59_002477"
     CDS             complement(10089..10349)
                     /locus_tag="U2R59_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8966819.1"
                     /translation="MDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTIN
                     PTLLLPSTGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(10327..10525)
                     /locus_tag="U2R59_002478"
                     /pseudo
     CDS             complement(10327..10525)
                     /locus_tag="U2R59_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302976.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3024 a         2052 c         1897 g         3552 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctt
//
LOCUS       DASHXG010000077        10493 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.081, whole genome shotgun sequence.
ACCESSION   DASHXG010000077 DASHXG010000000
VERSION     DASHXG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.081"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..357)
                     /locus_tag="U2R59_002479"
     CDS             complement(<1..357)
                     /locus_tag="U2R59_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEM8966820.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLG"
     gene            complement(709..1068)
                     /gene="rplT"
                     /locus_tag="U2R59_002480"
     CDS             complement(709..1068)
                     /gene="rplT"
                     /locus_tag="U2R59_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEM8966821.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1121..1321)
                     /gene="rpmI"
                     /locus_tag="U2R59_002481"
     CDS             complement(1121..1321)
                     /gene="rpmI"
                     /locus_tag="U2R59_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEM8966822.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1393..1917)
                     /gene="infC"
                     /locus_tag="U2R59_002482"
     CDS             complement(1393..1917)
                     /gene="infC"
                     /locus_tag="U2R59_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEM8966823.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1961..2086)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2237..2869
                     /locus_tag="U2R59_002483"
     CDS             2237..2869
                     /locus_tag="U2R59_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HEM8966824.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2871..3776)
                     /locus_tag="U2R59_002484"
     CDS             complement(2871..3776)
                     /locus_tag="U2R59_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEM8966825.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3861..4520)
                     /locus_tag="U2R59_002485"
     CDS             complement(3861..4520)
                     /locus_tag="U2R59_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEM8966826.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4836..5780
                     /gene="mvk"
                     /locus_tag="U2R59_002486"
     CDS             4836..5780
                     /gene="mvk"
                     /locus_tag="U2R59_002486"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEM8966827.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5773..6750
                     /gene="mvaD"
                     /locus_tag="U2R59_002487"
     CDS             5773..6750
                     /gene="mvaD"
                     /locus_tag="U2R59_002487"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEM8966828.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6763..7848
                     /locus_tag="U2R59_002488"
     CDS             6763..7848
                     /locus_tag="U2R59_002488"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEM8966829.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7845..8909
                     /locus_tag="U2R59_002489"
     CDS             7845..8909
                     /locus_tag="U2R59_002489"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEM8966830.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9158..9961)
                     /locus_tag="U2R59_002490"
     CDS             complement(9158..9961)
                     /locus_tag="U2R59_002490"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEM8966831.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9981..10286)
                     /gene="kduI"
                     /locus_tag="U2R59_002491"
                     /pseudo
     CDS             complement(9981..10286)
                     /gene="kduI"
                     /locus_tag="U2R59_002491"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10268..>10493)
                     /locus_tag="U2R59_002492"
     CDS             complement(10268..>10493)
                     /locus_tag="U2R59_002492"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HEM8966832.1"
                     /translation="LWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLI
                     VIIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3104 a         2219 c         2008 g         3162 t
ORIGIN      
        1 acctaatgac atcaagatcg gcaacacaat aactgcaata gaaatcactg gtccgattcc
       61 tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg tgattcttgg
      121 cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc cgctatctac
      181 tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt tggcgtactc
      241 agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc cttccatcgc
      301 cgagtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag tagccatgat
      361 gacaaaagcc gaccatcaag ttgtagcctt ttacacagta ccagaccatg aaaaagaatg
      421 agataactaa caaaatacca ataataatat cactcatgtt attcctccgt ccattttgtt
      481 tttctgataa gcaaactaat atatcagtca aactcattct aacttatgta gttagcgctt
      541 tcattaaagg atgaccataa atgttcagtt ttcaattaaa aaaccttaat tatgttattt
      601 tagacttata cgttattgtc ctgtttcatt tgatggagga ttgtaaataa aaaaagagga
      661 aagaacataa cttttcgtta tcttctttcc tctttataat tgtttagctt atttagccaa
      721 agcttctttt gcttggtcag ccaatgcagt aaatgctgct gcatcgttaa cagccaagtc
      781 agctaacatt ttacggttga tgtcgatttc agcaactttc aaaccgtgca ttaattttga
      841 gtagctcaag ccattcatac gagctgctgc gttgatacga gcaatccaca atttacggaa
      901 gtcgcgtttc ttttgacgac gatcgcgata tgcgtagttg tatgaattca ttacttgttc
      961 ttttgctgtt ttaaataaag tgtgttttga accgtagtaa ccttttgcta attttagcac
     1021 tcttttacga cgtttacgag ttactgttcc acctttaaca cgtgccatgt ataattcctc
     1081 ctaataaaaa taaatcttca gattctgtta tttgtacttc ttatttcatt tttgctagtt
     1141 gttggcgaat acgtttgaag tcgccactag aaaccatgct tgctttacgc aattgacggc
     1201 gttgtttttt tgttttgccg tggaaacggt gacttgtaaa cgcgcggaag cgtttcaatc
     1261 cgcctttacc agtacgtttg aaacgttttg ctgatccgcg gtgtgttttt tgttttggca
     1321 tgactatatt tcctcctcaa aatctttcgt tatccgacta tcggctgtcc aacagccagt
     1381 tagtcattca aattacttac tgtcgttttt cggtgccagc gtcaagaaca tgctgcgtcc
     1441 gtccattttc gctttttgtt ccactgttgc aatatccgca gtttcttcag ctaagcgatt
     1501 caagactttt tgaccaattt ctttatgggt aatggcacgg cctttgaaac ggatagaagc
     1561 tttcacttta tcgccctttt ccaagaactt acgtgcatta cgaagttttg tattgaagtc
     1621 attcaagtcg atcgtaggac ttaagcgaac ttcttttaca ttgatcactt tttgtttttt
     1681 acgcgcttcg cggtctttct tttgttgttc gaaacggtat ttaccgtagt ccatgattcg
     1741 cgcaactggt ggtttcgcac caggggcaac taacacaaga tccaagtttg cttgttctgc
     1801 aatattcaat gcttctgctt ttgtcttaac tcctaattgc tcaccatctg aaccgatcaa
     1861 tcgtaactct cgtgcacgaa tgccgtcgtt aaccatcata tcctttgcta tggtcattca
     1921 cctccaaata ttatgagaga aagaaaagct taccgaataa acggcaataa aaaaacgagt
     1981 tctcttacag aacccgcgcg tacttcacct aatagaacca gtgaaaacta tctagcccag
     2041 tgacattatc aactaaggcg agaagcgggt gcttctgctt ttatttctca accattatag
     2101 tatagcaaaa actaatcttt ttgtcaatgt ttttcataca gtttgtcttc cttttctgaa
     2161 aatgattaga ttagcaggct ttctagcagt gattcccgct tctttgctat actaaagaaa
     2221 aacgaggtga acccacatga aaaaaatcga acctattcca ccttctcttc ctcttcttac
     2281 aaagggagag ttttatttag aagatgagga gatcttctct ggtcttctga tcaacggagg
     2341 taaccaaagc tatctcgatg ccaaaaatat ggtattaaga gagagtcata tccaaaaact
     2401 tacgatgcaa aaaacaggtt tacgtcattt tgaatgcagt aatgtcattt ttgaaaaatg
     2461 tgatttttcc aatctggagt ggattggtgg cagtttccac caagtcgtgt ttcatcaatg
     2521 taaattaaca ggtacgaatt ttgccgaaag ttatcttcga gactgtactt tcactgattg
     2581 tattgcttcg atggcttcct ttagtagtac aaacttgaaa gctgtctcct tcgatcattg
     2641 tcaattagaa gacagcgaat tttatgaggt cacttggaaa aacctttttt tgtctgacaa
     2701 tcagttaacc ggttcgaact ggtttcgaac ttctctgaag ggattagact ttacgactaa
     2761 tttcttcaca acaatcgctt tatctcaaga ttctttggcg ggactaatcg tcaatcaaga
     2821 gcaagcactt gtgatcgccc aagcccttgg tttgcagatc aaagactaga tcaacgaatc
     2881 cgccgccaca gtgcaataag catccaaata gataagacca aactgatgat caaggcgatt
     2941 tcccatccga aaacggaatg ggtaaagggt aactggagat tcattccgaa gaatcctgtc
     3001 acaatagttg gaacggtcaa gatcagcgac cagaccgtca aaaatttcat cgtgtcattc
     3061 aagttgttat tcagcaaatt attataagtg ccagagagct ggtctaaaat ctgcgaagct
     3121 aagttcgtca tttcaactgc ttgtcgtgct tcgatcagtg catcgtccaa ctcttctttt
     3181 tccttttctg acaacttgcg ataaatagcc agtgccttga tttgttctaa aagtactaca
     3241 ttttgttttg ttcctgtaac taagtaaacc aaaccgatct ctaaatctga aagttgcagc
     3301 agattcttgt tcgttgtttt ttctcttaat ttcagattaa gccgctgacg ttcactattc
     3361 acttcctcga ttaaaggaaa aaaggaatca gaaatcaaaa acaatgtacg aaacaataaa
     3421 ctgtatacac tcatgtctgg catccgttcc aaaagcgatc gaattagtcg aatcacgtac
     3481 tcggtattcg gcgtggtaaa tgtaaacaaa ccgtcttctt ttaaaataaa agcgatagga
     3541 ctagtttcat aatgattatc gactttttgc tggtgcggaa catttgatac aagcagtaac
     3601 gcttcatcaa aagaatcgta ctctacgcgc gcccgttcat ttttatctag agaataagtc
     3661 agcatctcgt cactaatgcc atattcttct tttaagtttt taacagctag cacatcgttt
     3721 tgctgtacat tgatccaaaa attacggtct tgattaaaat agtgtttttc ccgcatactc
     3781 tatcctcctg acatttgttt ccagtataaa gaaaaaagtc gctcaaataa aggtttaccc
     3841 tttatttgag caactgtaaa tcaaatggat actttggttt ggcgaatctc tgctaatttt
     3901 tcttcgatca ttttcaagac ttcttctttt gcttgaggat cttccacaaa attatagcgg
     3961 tctccatcga tttggatttt tggactttct ttgtattctt cataccattg atcataacgt
     4021 ctgttcaatt ctttgtaata atcgtataga cttgggtcaa aggacaattg ttcatacgaa
     4081 cgaccacgtt tttcgatacg ctctaacatc gtatcaaaag atacacgaat atgaactaat
     4141 aaatccggat gttttttatg ggcagcatag ggaagttctt ccatcatgtt ttccagcagt
     4201 tcatcataca cacaaacttc tgtttctgtt gctcttccta gatctgcatt tagatggaaa
     4261 agcagtgaat cttcataaat cgaacggtcc aatacattat tgtcatcttt cattgcttgt
     4321 ttgatgcttg caaaacgttt attcaaaaaa taaatttgca gcaaaaaagc atactgttca
     4381 gggtttgcat aaaataaggg caagacttca ttatcatcaa tcgattcata aaatgcctga
     4441 ctatcaaagt gttcagccat catttctgtt aaacttgatt ttccggcacc aattgtacct
     4501 gctaaaacga tcacgctcat ttacctccag ctcacttcat cactaaatat tgtgtttaac
     4561 tccaaccttt tttaaatata cccccaatat ctagtagtgt caattgtatt ttttctagtc
     4621 aaagaagaaa aaaagtcaaa aaattcttaa gaaaaaagtg ttttttcttt agaaaacgta
     4681 ttcttagttt tacttctgag atggttttag taaaataaag gaggaatgtt ttttgagacc
     4741 cttagtggac aaaaaaattc gtgaagcagc gcaactcgtt ttgggcgctt tattttttgc
     4801 ttaaaaatca cttttacgtg agaaggagtt agattatggc aaactatggt caaggagaat
     4861 caagcggaaa gatcatattg atgggcgagc acgcggttgt ttatggagaa ccagcgattg
     4921 cctttccttt ctatgcaaca aaagtcaccg cattccttga agagctggat gcaatggacg
     4981 atcaactggt ttcttcctac tattcaggaa atttagccga agctcctcat gcattaaaaa
     5041 atatcaaaaa attattcatt cacttaaaaa aacagcatga catccaaaaa aacttgcaac
     5101 tgaccattga aagcacgatt cctgctgaac gtggaatggg atcaagcgct gcagtcgcca
     5161 cagcagtcac tcgtgctttt tatgattact tagcatttcc tttgtctcgt gaaatactat
     5221 tagaaaatgt ccagctttcg gaaaaaatcg cccacggtaa tcctagtgga atcgatgcag
     5281 ccgctactag cagcttgcag ccgatttatt ttacaaaagg gcatcctttt gactactttt
     5341 ctttgaacat cgatgctttt ttgattgtcg ctgatacagg aatcaaagga caaacaagag
     5401 aagccgtcaa agatgtcgct cacctctttg aaacccagcc tcatgaaact ggacaaatga
     5461 tccaaaaatt aggatacttg acgaagcaag caaaacaagc aatcattgag aattcaccag
     5521 aaacgttggc acagacaatg gatgaatcac agtcacttct ggaaaagctg acaatcagca
     5581 atgattttct taatctattg atccaaacag caaaagatac cggggcattg ggtgccaaat
     5641 taactggcgg tggacgcggt ggctgtatga ttgcattagc acaaacaaaa acaaaagccc
     5701 aagaaatcag tcaagcactt gaagatgcgg gtgctgctga aacttggata caaggattag
     5761 gagtacatac ctatgtttaa aggcaaagca cgcgcatata ccaacattgc tctaatcaaa
     5821 tattggggta agaaaaatga agaactcatc cttccaatga acaacagcct ttcgttaaca
     5881 ttggatgcat tttatacaga gacagaagtc atcttttctg atagctatat ggtagatgaa
     5941 ttttatctag atggcacctt acaagacgaa aaagcaacaa aaaaagtcag tcagtttctt
     6001 gacctttttc gtaaagaagc cggcctctca ctaaaagctt cagtaatcag tcagaatttc
     6061 gttcctaccg cagctggatt agcctcctct gccagcgggc tagctgcttt agcaggagct
     6121 tgcaatactg ctcttaagct tggattagac gatctctctc tttcaagatt tgctcgacgc
     6181 gggtctggtt cagcttgccg aagtattttc ggtggtttcg ttgaatggga aaaaggccat
     6241 gacgacttaa gttcttacgc taagccagtc ccttccgatt ctttcgaaga cgatttagca
     6301 atggttttcg ttttgatcaa cgaccagaaa aaagaagtgt ccagcagaaa tgggatgcgt
     6361 cgaacagtcg aaacatccag tttttatcaa ggctggttag attccgttga aggggatcta
     6421 tatcaattga aacaagcaat caaaacaaaa gatttccaac ttctcggaga aacgatggaa
     6481 agaaacggac taaaaatgca tggaacgact ttagctgccc agcctccatt cacttactgg
     6541 tctcctgaca gcttaaaagc gatggatgcg gtgcggcaat tgagaaaaaa aggcattcca
     6601 tgctacttta cgatggatgc tggccctaat gtcaaagttt tagtggaaaa cagccattta
     6661 tctgaggtac aagaaacatt taccaaatta tttagcaaag aacaagtaat tactgcccat
     6721 gctggtccag gaattgcgat tattgaataa agggagattt ttatgattga agtatctgca
     6781 ccaggcaaac tctatattgc cggagaatat gcagttgttg aaacaggaca tccagcagtt
     6841 atcgctgcag tcgatcaatt cgtaacagtc actgtagaat ccgcacgaaa agtcggaagt
     6901 atccaatctg cacaatatag tgggatgcct gtacgttgga caagacgcaa cggagaatta
     6961 gttttagata ttcgggaaaa tccttttcat tatatccttg ctgctattcg tttgactgaa
     7021 aagtatgcac aagaaaaaaa cattctttta tccttttatg atctgaaagt aacaagtgag
     7081 ttagacagtt caaatggccg gaaatatgga ttgggttcta gcggtgccgt gaccgttgca
     7141 acggtcaaag ccttgaatgt tttttacgcg ttgaatttat ctcaattgga gattttcaag
     7201 attgcagcac tagccaattt agcagttcaa gataatggtt cctgcggcga catcgctgct
     7261 agctgttatg gtggctggat cgctttctca accttcgacc atccttggct ccaagaacaa
     7321 gaaactcagc attctatcag tgagttactt gccctggatt ggccaggtct atccattgag
     7381 ccattgattg ctcctgaaga tttacgttta ttgattggtt ggacgggtag ccctgcctct
     7441 acttctgatt tggtcgatca agttcaccgt tcgagagaag acaaaatggt ggcttatcag
     7501 cttttcttaa aaaacagtac agaatgtgtc aacgaaatga tcaaagggtt taaagaaaat
     7561 aatgtaacgt tgatccaaca gatgattcga aaaaaccgac aattactgca tgatttatct
     7621 gcaatcactg gggtcgtcat cgaaacgcct gctttgaaca aattgtgtaa tttagctgaa
     7681 cagtatgaag gagccgcaaa atcttctggt gcaggtggtg gcgattgcgg aatcgtaatt
     7741 gttgaccaga aatctggcat ccttccttta atgagtgcat gggaaaaagc agaaatcact
     7801 ccactgccgt tacatgtcta tagcgatcaa agaaaggaaa accgatgaat cgaaaagacg
     7861 aacatgtttc actagctaaa gcctttcatg ataaacaaaa aaacgaattt gacttcgtac
     7921 ggatcatcca taaccctttg ccgcaaatag cagtttctga tgtcgatcta agtacacagg
     7981 cagttgggtt tacactaagc agcccatttt atatcaatgc gatgactggc ggaagcgaaa
     8041 aaacaaaaaa aatcaaccaa gatcttgcaa tcgtcgcaag agaagcagat ttgatgattg
     8101 ccactggttc agtcagcgct gccttgaaag acccttcttt agccgatact tatacgatta
     8161 tgcgacaaga atatcctcac gggaaaatca ttgccaacat cggtgcaggg acttctgtcg
     8221 aaagagccca agaagctatc cgattgtttc acgcagatgc cttacagatt catttgaatg
     8281 cacctcaaga gttggttatg cctgagggag accgtgattt taccaattgg aaagtactta
     8341 ttcaagagac tcaaacagcc attgacgtcc ccctcatcgt aaaagaagtc ggttttggca
     8401 tgacaagaga aacgctcaat gatctagctg ctttaggagt tcatacagtt gatatcagcg
     8461 gtcgaagcgg aacaagcttc acccagatcg aaaacgcccg tcgctccaag cgggaactga
     8521 gttatttagc tgactggggg caatcgacag tctcttcatt gcttgaagca aatgaagcag
     8581 acacttctat ggaaatccta gcctccggag gtatccgcaa tgcctatgac atatttaaag
     8641 ccctttgtct cggcgcaaat gcagtgggta cttcaggaac cgtactgacg catctgatga
     8701 atcacggcgt agaagaaact attatactga tgaagcaatg gcaagaagag cttcgtctgc
     8761 tttatactat ggtcggcgca acgaataccg cggccctaca ccaacaatca ctgatctttt
     8821 ccggaccagt gaaggattgg tgcgaagcaa gagggatcga cttagtgaag tatggaagac
     8881 gcacagaaaa gagcgtggga caaaagtaaa gaacactttt atcccacgct ctaaacacgt
     8941 ataaacggcg gaagcaaaag caactccttc ggaaataagc tgaaattcac aaaaatttga
     9001 aaagcaattt tcgtgaattc cttcttattt cttggagtta aacgcttctg tcccagcctc
     9061 ttttttcgaa taaatgatgt ttaatcagct gtccttcggt attcgttcaa gccgctgatt
     9121 tcacaacctc tccactaaac ggtgtactaa agctctttta aggttgtttt ccgatatagg
     9181 caagtatgcc tccgtccaca tacaagacat ggccgttaac gaaatcagat gcgctagaag
     9241 ccaagaagac agatggtcca gccaaatcga ttggctcgcc ccagcgtgct gctggcgtac
     9301 gtccaacgat aaattgatcg aatggatgac gttcaccgtt ttcttgtgtt tcgcgtaatg
     9361 gagcagtttg cggtgtagca atataacctg gtccaattcc attacattgg atattgtatt
     9421 gaccgtattc agaagcgatg tttttcgtca gcatttttaa tccgcctttt gccgcagcat
     9481 aagcactgac cgtttcgcgt cctaattcac tcatcatgga gcagatattg atgattttac
     9541 cgccgccttt ttcgatcata tcccgaataa ctgcttttga aacgatgaat ggggcattta
     9601 aatccacgtc gattacttgg cggaagtctg ccgcatccat ttcgatcatc ggtgtccgtt
     9661 tgatgatccc tgcattgttg actagaatat caactgaacc tacatcttct ttgatctgtt
     9721 gaaccatcgc ttgaaccgct tcttcatcgg tcacatcgca gacataacct tttgcatcga
     9781 tgcctgcttc tttataatgc gctatacctt catcaactga ttcttgattc aagttattaa
     9841 atacgatttt tgctcctgct gtagctaaag agcgtgcaat ctcaaatcca ataccataga
     9901 cagcaccggt gactaatgct acttttccat ctaaacgaaa catatccata ctaaattcca
     9961 tcattttctc tcccttatgc ttattttaat tgatccattt gcaccatatc catgtctgta
    10021 taggtgatat tttctccgca cattgcccag atgaatgagt aattgcttgt acctacacct
    10081 gaatggatcg accagcttgg cgaaataatg gcttgttcat tgtctacgac taaatgtttt
    10141 gtttcatctg gtttgcccat catatggaac acacgtgtat cttcattggc ataatcaaaa
    10201 tagacataag cttccatacg acgttcatgt gtatgacaag gcatcgtatt ccaagcactt
    10261 cctggttcta aaatcgtata acccatttat aaatgacagc tatcgctgaa gcttctactg
    10321 ctgtaaatat ccccgtcaag ataccaccga taatgatgac aatcaataga aggctaggaa
    10381 tcgcctcttt tattattttt ccagcatgag ccatctgtcc tttttcgaca acagggtatt
    10441 tattcttttt agcaacgatg aatgctacta gcatgattcc tagcgcccac aaa
//
LOCUS       DASHXG010000078        10409 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.082, whole genome shotgun sequence.
ACCESSION   DASHXG010000078 DASHXG010000000
VERSION     DASHXG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.082"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(45..1364)
                     /locus_tag="U2R59_002493"
     CDS             complement(45..1364)
                     /locus_tag="U2R59_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8966833.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="U2R59_002494"
     CDS             complement(1361..2014)
                     /locus_tag="U2R59_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8966834.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..2822
                     /locus_tag="U2R59_002495"
                     /pseudo
     CDS             2302..2822
                     /locus_tag="U2R59_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..3440)
                     /locus_tag="U2R59_002496"
     CDS             complement(2724..3440)
                     /locus_tag="U2R59_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HEM8966835.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3490..3699)
                     /locus_tag="U2R59_002497"
     CDS             complement(3490..3699)
                     /locus_tag="U2R59_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966836.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            3976..5249
                     /locus_tag="U2R59_002498"
                     /pseudo
     CDS             3976..5249
                     /locus_tag="U2R59_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5356..6387)
                     /locus_tag="U2R59_002499"
     CDS             complement(5356..6387)
                     /locus_tag="U2R59_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966837.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6394..7224)
                     /locus_tag="U2R59_002500"
     CDS             complement(6394..7224)
                     /locus_tag="U2R59_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966838.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7221..8036)
                     /locus_tag="U2R59_002501"
     CDS             complement(7221..8036)
                     /locus_tag="U2R59_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8966839.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8033..8857)
                     /locus_tag="U2R59_002502"
     CDS             complement(8033..8857)
                     /locus_tag="U2R59_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HEM8966840.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSENMQDIQELMRG"
     gene            complement(8847..9947)
                     /locus_tag="U2R59_002503"
     CDS             complement(8847..9947)
                     /locus_tag="U2R59_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEM8966841.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10125..>10409
                     /locus_tag="U2R59_002504"
     CDS             10125..>10409
                     /locus_tag="U2R59_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HEM8966842.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPY"
BASE COUNT         3194 a         2298 c         1695 g         3222 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaaacaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag aagtaccgtc
     2701 ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag ccgctcaaac
     2761 ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc gatgaaccgt
     2821 tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc agtcgccaca
     2881 tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg ttcaggatct
     2941 tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac gtaggcaacc
     3001 agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta atcgattgct
     3061 cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca tgaactatcg
     3121 taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat ttgttctaac
     3181 aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt atgcccgcta
     3241 aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg tgctgcttgg
     3301 gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg tttcaagcac
     3361 aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt cacaaaggaa
     3421 tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc ccgcagttca
     3481 gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat gttcagcatc
     3541 cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg ctgccgtccc
     3601 aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca gtaaataggc
     3661 ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat catcgtccca
     3721 tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa acaagcaaaa
     3781 gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa agtcaaaggt
     3841 gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat cagtcctttt
     3901 gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca caacacaatc
     3961 aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg aatcaaagat
     4021 ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa cagtatcgtt
     4081 gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca ggtgaatcaa
     4141 catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa taagtgtgcg
     4201 aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg ctgtcacacc
     4261 tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa acaagtacat
     4321 tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc taaacattgc
     4381 ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat gacaaacgtg
     4441 aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt gaaaaatcaa
     4501 gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact ggatattctt
     4561 ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg acgtgcacgt
     4621 ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct gataaaagag
     4681 tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca cctcattcgc
     4741 agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga tccaatacaa
     4801 gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg acaggacacg
     4861 cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt aaccgaaagt
     4921 gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta tgcttactat
     4981 caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca gcttgtaaaa
     5041 acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt tataaactat
     5101 gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat agaaaatctg
     5161 catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga accagaattt
     5221 tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc agaaaatcaa
     5281 ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga gccagaaatg
     5341 tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt ccacagggat
     5401 tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt cccgatcgtt
     5461 caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc gttgaatgtt
     5521 gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag gaaccggttc
     5581 aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag cggaaaactc
     5641 gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga taaattccgc
     5701 aacaaatcgg ctctgaggat tctgatacaa ttctttcgag gtggaaacct gagccacccg
     5761 cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt ggtcatgagt
     5821 cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc gctgcagctg
     5881 ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga ctttcggttc
     5941 agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa gaaactggac
     6001 atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa ccttttcctg
     6061 aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt caaaaacagt
     6121 catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat ccttcgtagg
     6181 cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt gttccaatcc
     6241 cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta aagtaaccag
     6301 ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat caaaaaacag
     6361 attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg gcttcttttt
     6421 cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc gataagtcag
     6481 cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca tcacagcgct
     6541 agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg tctgaaatcg
     6601 accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa aaatcatcag
     6661 agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa taatcgtaga
     6721 catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa ttaagcgcat
     6781 ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg cacctaccaa
     6841 cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg ttaccaaaat
     6901 cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat tcaaacgagg
     6961 gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg tcaccaagac
     7021 cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt ccgtcagcag
     7081 ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc atttagtgga
     7141 gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa agcagaacaa
     7201 aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg aataatcaac
     7261 attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa attaggcttg
     7321 gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt tacattactg
     7381 ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa gatgacaaag
     7441 gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc atacgctgat
     7501 gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt catgctggga
     7561 tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt caatccccac
     7621 caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac acctacattc
     7681 cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc tgccaaattg
     7741 gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca taaacataaa
     7801 ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac gctgttaaca
     7861 aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa tgtccactgg
     7921 ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag cagtaaaaat
     7981 gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc tttcatcccc
     8041 tcatcaattc ttgaatgtcc tgcatattct ctgacggtgc aattcctaat aaccagcaaa
     8101 acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg cgtttatttg
     8161 aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc agtccgtgcg
     8221 catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc cattcaggaa
     8281 ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca tgagaatcgg
     8341 cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa aagtctggct
     8401 gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg taagtgtcct
     8461 cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg cgatcaacca
     8521 aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg gcggctcctg
     8581 tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat cgctgagcat
     8641 ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt acttcgtata
     8701 acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct tgctggtgct
     8761 caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga cagccgtcta
     8821 gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc cgcctgccaa
     8881 agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac tggcaccgcc
     8941 gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag ctctaccttg
     9001 cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga taaaatatat
     9061 tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa ggttgtatac
     9121 ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga gtcaatttgg
     9181 tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc acctttttca
     9241 agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat ttttttgtag
     9301 taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc cgcagccaat
     9361 acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg atagtcaccc
     9421 tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc ggtgataaag
     9481 gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc ccaatccgga
     9541 atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc agccaacgga
     9601 ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc tgattcaaac
     9661 ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc gtattctttt
     9721 tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc caagctggca
     9781 atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc tgccgcagcc
     9841 gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac tgttgctgca
     9901 caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca ttcttctccc
     9961 ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc ttgaaaaggt
    10021 ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc ccgttaacct
    10081 tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag tattatgatc
    10141 agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac tatttagcct
    10201 atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca tctaccggaa
    10261 aagatgacat tccggattat ccagcctata taaacaaact ggactcttta aaagaaacct
    10321 attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa gaagagcgga
    10381 tcgtggatta cctcgctcag catccttat
//
LOCUS       DASHXG010000079        10248 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.083, whole genome shotgun sequence.
ACCESSION   DASHXG010000079 DASHXG010000000
VERSION     DASHXG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.083"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="U2R59_002505"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="U2R59_002505"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEM8966843.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="U2R59_002506"
     CDS             complement(1173..1868)
                     /locus_tag="U2R59_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEM8966844.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="U2R59_002507"
     CDS             complement(1881..2597)
                     /locus_tag="U2R59_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEM8966845.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="U2R59_002508"
     CDS             2927..3532
                     /locus_tag="U2R59_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HEM8966846.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="U2R59_002509"
     CDS             3857..4180
                     /locus_tag="U2R59_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEM8966847.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="U2R59_002510"
     CDS             4362..5732
                     /locus_tag="U2R59_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEM8966848.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="U2R59_002511"
     CDS             complement(5862..7163)
                     /locus_tag="U2R59_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEM8966849.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9351)
                     /locus_tag="U2R59_002512"
     CDS             complement(7393..9351)
                     /locus_tag="U2R59_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEM8966850.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="U2R59_002513"
     CDS             complement(9528..9794)
                     /locus_tag="U2R59_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEM8966851.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
BASE COUNT         3007 a         2120 c         1867 g         3254 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataa
//
LOCUS       DASHXG010000080         9894 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.084, whole genome shotgun sequence.
ACCESSION   DASHXG010000080 DASHXG010000000
VERSION     DASHXG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.084"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(115..2235)
                     /locus_tag="U2R59_002514"
     CDS             complement(115..2235)
                     /locus_tag="U2R59_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEM8966852.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2465..3643
                     /locus_tag="U2R59_002515"
     CDS             2465..3643
                     /locus_tag="U2R59_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEM8966853.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3659..4417
                     /gene="aroD"
                     /locus_tag="U2R59_002516"
     CDS             3659..4417
                     /gene="aroD"
                     /locus_tag="U2R59_002516"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEM8966854.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4440..4925
                     /gene="ybaK"
                     /locus_tag="U2R59_002517"
     CDS             4440..4925
                     /gene="ybaK"
                     /locus_tag="U2R59_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HEM8966855.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4996..6249)
                     /locus_tag="U2R59_002518"
     CDS             complement(4996..6249)
                     /locus_tag="U2R59_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEM8966856.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6366..7715
                     /gene="gdhA"
                     /locus_tag="U2R59_002519"
     CDS             6366..7715
                     /gene="gdhA"
                     /locus_tag="U2R59_002519"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEM8966857.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7827..9173
                     /locus_tag="U2R59_002520"
     CDS             7827..9173
                     /locus_tag="U2R59_002520"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEM8966858.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9481..9867)
                     /locus_tag="U2R59_002521"
     CDS             complement(9481..9867)
                     /locus_tag="U2R59_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HEM8966859.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3154 a         1800 c         2025 g         2915 t
ORIGIN      
        1 aaaaatctga gccagaatga ggttcattct gacccagatt tgattttgta caacccatca
       61 gtccttattg acaaagagcc taattttgtc gctgctcctt ttaaatttat tttatcattc
      121 ggaagaactt gtggtcgttc cgtgaagttc ttggtacgtt tgcgttttat aaagatcaac
      181 agttgattgt ccgttgtgtt cactaaagac actagttgac ttgtcaccaa gagatttttc
      241 agcttctttt aatttctcta agccattctt gtagtcataa tcactggtat caattgggtc
      301 taatccacta ttcgtataga accgaagaag atcaccatta ttgatttggt cagaaacagc
      361 taactgttta tcaacttttt ctttcagtga atcaatttca ttctgtactt cctcagtagg
      421 ttcagtaata gcttcaccag tttcgttact atagatcgta ccaccgtagt aagtatattt
      481 tggtgtaaca aaatcaccat cacggaaaga aacaagctgt tcatgatctt tcgagaatag
      541 atcttgtcct aactgaatat aattttttgt atctacacct agtaagtgaa gtaatgtagg
      601 caaggcatca acttgtccgc cgtaagtgtg attgattccg ccctgtgttt gtccagggat
      661 atggatcata taagggacac gctgcatttg tgcattgtcg tagtttgtcc aagtagaact
      721 tgtttttcca actaattcag ctagattttt atttcttgaa ttcgagacac cgtaatggtc
      781 accgtaaagg acgatgactg aattatcata caagccgctt tctttcaaat aattgaagaa
      841 ttcttgtacg gcggtatcta aataattggc tgtcgcaaag taaccgttga tcgtttcatc
      901 atttgtattg gctaacggga atcctgcttc gtcattggtg aattttgaat aaggataatg
      961 gttagataca gcaatgaatt ttgaataaaa tggttgttgc agacgttcca agtattgtac
     1021 ggattgttgg aaaaatggtt tatcatgcaa cccgtattgg aacgaattgt catcattaac
     1081 atcataataa gaagaatcaa agaaataatc atatcctaaa ttcttgtatg tctcgtttcg
     1141 attccagaat gtaccagcgt tcccatggaa taccgcacta gtgtaacctt gtgtttgact
     1201 taaaatatca ggtgcagctt ggaaagtatt ttttccgcct aattgtgtga acaaggagcc
     1261 ttgattcaag ccaaacaatg aattttccat cagcgtttcc gcatcgcttg tttttcctgc
     1321 ttttacttga tggaaaaagt tgtcaaaact gaacgtgctg ttgctgtggt aaagactatt
     1381 gatgaaaggt gtaacttcat gctggagacc attctcatct gtcaatttat aatcgatcag
     1441 gaattgctgg aagctttcta aatggatata aatcacattt tttcctctag cgagcccgaa
     1501 caaatcgtca tttggtgctg cataatgttc ttttacataa ttttctactt ctttcatatc
     1561 attgggactt gcttctgccc gcacttggtt tgtctggtaa gtttgaacac cgtcataaac
     1621 catgaaagca ttcaagccaa gatatttgac caaataatca cgagagaatg ttcgagtcag
     1681 caattctgga cgatcagctt ccgccataaa aagatttcct gagaaaatca taactgctaa
     1741 tgtagagatc gcaaaagcca ttcttgctcg gatcgggcga gggtccaact tgattttttt
     1801 tgcaatcagc agaacagtca agataataaa atcgatccaa tagatcacat catatgggcg
     1861 aaacagtcga atggcacttt ctcccagacc actcgctact ttcccagcac ctaaaatcgt
     1921 gttgatcgta atgaagtccg tgaattctcg ataataagtg acattcgaaa aaacaagcaa
     1981 tgtcaaaaga aaataaatga ccatcatcgt gatataagca actctagggc gtctgatata
     2041 aagagcaatt ccaagtaata acaatgtagt tgcaataggg ttgataaaca agataaagta
     2101 ttgaatgcca ctttcgattc cgagatggaa atcaactaaa taggcaaaaa tcgttttcaa
     2161 ccaaagtaaa acgactagta aagaaaaaaa tccgagcctc ttattcaaaa aggcaggtgt
     2221 ttttatacat ttcaagataa tcttcctttc tgcacttctt aatcacagaa gtgtcctgaa
     2281 accatgttac acagctcact tattctcatt tattttacta gtatgacaat atagtgtcaa
     2341 ttgaaaccag aagtttatgc tgtttcatta aggttttctt taagcttcat gaaaaaatga
     2401 gcagtaagac aagtcctatg ttttttgtta tacttgggaa gagaaagcta aagcaggtga
     2461 aggaatgaaa gtaaaagtaa aaaaaagagc aagcaatcga ttgaaaaaag gatatccact
     2521 gatccaaaaa gaagaccttg ctcatcccca aaaagaaacc acgcaatggg tggaattagt
     2581 tgattcgcaa aaccaattta tcgcaaaagg atatctagga aagcagaata agggaatcgg
     2641 ttgggtattg agccagcaga acatcccatt tgatcaatct ttttttgaag aattttttgt
     2701 gaagtcaaaa gaaaaaagaa ctttcttttt ttcagatgat tctactaccg cttttcgtat
     2761 attcaatgga gaaggagacg ggatcggcgg tctgattgtt gattattatg caggttatgc
     2821 tgttttttct tggtataacg aaacgttata tgcacatcgt gaattattga ttcaagcttt
     2881 tcgtgaaatc tacccggaaa tcataggagg ctatgagaaa attcgatttg aatcagtaaa
     2941 tctgcctgag agccagttca tttacggaaa agaggcaccg gaacccttga tcgtaaaaga
     3001 aaacggagta aaatttgccg tttatttaaa tgaaggatta atgactggga tctttttaga
     3061 ccaaaaagaa gtacggggat cattagcaga aggtttcgct tctgggaaaa cagttttgaa
     3121 catgtttagt tataccggcg ccttttctgt tgctgccgca atgggagggg caatcgaaac
     3181 aacaagtgtc gatctagcaa aacgcagttt aaaaaaaaca caggaacagt ttgaagtgaa
     3241 tggtttggat gtcgatcagc aaaaaatcat tgttatggac gtattcgagt atttcaaata
     3301 cgccaaaaga aaacaatttt tatatgacat gattgtattg gatccaccaa gttttgccag
     3361 aaataagaaa aaagtctttc gcgtagcaaa agattatggg gaactggtca aggatagtct
     3421 ggatatttta gcagaagacg ggatacttat tgcgtctaca aatgctgcga atgtctcgat
     3481 agaacaattc caaacaatga ttgaagagga attccatgcc aaaaatgttt cttttgaaca
     3541 acttgcttta tatcgtctgc caaaagattt ccagacgacg gatacctttt tagaaggcaa
     3601 ttatctgaaa gtgtttgttt atcaaattaa aaataaccat tagaaggagc gatgcagaat
     3661 ggttcgggta aagggattga atataggaag cggtagacca aagatttgtg cgcctcttat
     3721 cggggccgtc cgagaggaag tattacgtga agcagttctt gcacgtgaag caggggccga
     3781 tttagtcgaa tggcgagtcg atcattatcg tgaagttttt tcttttgatg aagtagcaga
     3841 aacattggtt cttatccatg agatgcttga tggactgccg ttattattta cgtttcgtac
     3901 cttagctgaa ggcggagaac aagacatatc gatccgtcag tatcgcgacc tttatgaaca
     3961 tgtgatacac acaggattag tagatatggt cgatatcgag ttgttcaaag tagaaagtct
     4021 aggaaaaaga ctgatagagg aaatcaagtc tttaaacatt cctttaatta tcagtagtca
     4081 tgattttaaa gaaacaccag cagaccctgt cttgctttac cgattgaatg ttatggaaca
     4141 ttttggagcc gatatcggaa aactggcagt aactcccaat aatgaacgag atgttttgcg
     4201 gttgatggag ttgactagac gggcaaatgc ttttgtctcc atgcctatta ttacgatgtc
     4261 catgggaaat cttggtaaaa tttctcgtct ggttggcgga acgacgggtt ccgttatgac
     4321 atttggttcc ttaagcagcg attctacttc tgctccagga caattaccgg tcaaagcatt
     4381 gaagcaaatt attcaattat taaatgaacc gttgtagaac aagtttgagg tgatattttt
     4441 tggcaaagaa aaaaatagta aaaacgaatg caatccgtat ggtcgaacaa aaaaagattc
     4501 cctatacaga gcacgaatat gagtgggacg aaagccacct aagtgcgtca tcggtcgctg
     4561 aacagcttcc agaaagccaa tctcgtatat ttaaaacact ggttgctgtg ggcaatgtga
     4621 cggggcctct tgttgctgtg ataccgggag aagccgaatt gaatctaaaa aaattagcaa
     4681 aagtttcagg gaataaaaaa gtagaaatgc tccatttaaa agatttggaa gcaacgaccg
     4741 gatacatacg tggtggctgc tcgcctatag gtatgaaaaa actatttcct acttatttag
     4801 atcaaattgc agaaagctat gaacaaatca ttgtctcggc tggcagaaga gggctacaga
     4861 tggagttagc acctcaagat atctgtgcat taacgagcgg acaatttgca gatataaaac
     4921 aataaatcat acgtataaaa gaaagaagga ggccgggatg ttgtttgtcc agtctccttc
     4981 tttctttttt atacattatg ctctttgccc ggcattcatt cctgctacat gccctgtagc
     5041 gaaagccgct gtgatattaa agccgccagt ataaccattg acatccagta attctcccgc
     5101 aaaatacaga ccatcaatga ttttactctc caatgtttta ggataaattt cctttagaga
     5161 aacccctccg ccagttacaa atgatttctc aataggaaaa gttttgttga ttgatagctt
     5221 aaactctttg catagttgaa caaaatcttg aatttgtttt tgagaggctt gttgtcctgt
     5281 cagatgatcc atttcaagcc gctcaagaaa gaaaactaac aatcgctcag gcaatatacc
     5341 atgccaagca ttgaccaagt tctttttggt tgctttactt ttttctgtca atatatgaat
     5401 aagctcttgt ttggtttgtg tagggaaaca atccagagaa agtgtcactg gttctcccgt
     5461 tttctctaat tctttattga caaaacttga acaacgcagt gcagccggac cagaaatacc
     5521 gaaatgggtg aaaagtaaat ccatcgtatg ttcagtcaat acacgacctt ttttatttaa
     5581 aacgcgtaaa gtgatgtctt gtaaagaaag cccttgaagt gttttctcct gaatatacgg
     5641 ttcatccgat atcaaggggg actctgtcgc ataaagaggc gtcaccgtgt gacccactcg
     5701 cttcacgatc ttgtacccat ctccagtaga accagtagat ggataagtcc gtccaccagt
     5761 tgttaagata atggcaggag catggaactc ttcgaattcc gtgcgtatac cgtaaatttt
     5821 atgttctttg tggatcaatt tctctactcg agtagagaat agaagcgtca catctagttc
     5881 tttcagacga ttgagcaatg cttcgataat cgtttttgat ttatttgtta caggaaacat
     5941 ccgtccatga tcctcttctt ttaaatgtac gccttgtgat tcaaagaagt tcatgatatc
     6001 gaaattattc cattgcgcaa acgtactata taaaaacttt ccatttccag gaatatgtgc
     6061 aatcaaatca tcaacaggac gattgttcgt aacattgcac cgaccaccac ctgtcatcag
     6121 tagttttttt cctgcttttt tgtttttttc gatcaagagt acgcgtgcgc cttgttcagc
     6181 tgcactgatc gctgccatca tcccgcttgt tccagcgccg actacgatca catcatacag
     6241 tttttccatt ccctcacctc aaggaaagtg tagcatatct gaagaaagaa aacagaaaaa
     6301 aatgttttga gccaaaagag aaaatgagct aaaatgaggg aagataagca aaggagcgtg
     6361 gaacgatgac aaacgcaaca gaatatgttc aagcaattca agaaaagcta catcaaaagg
     6421 atcaagggca agaagaattt ttacaagcaa tcgatgaatt catgcccacg gttatgtctt
     6481 ttttggacac tcatcccgaa tatatcgaaa agaatatctt agaactttta acggaaccag
     6541 aaagagttat tcaatttcga gtgccttggc aagatgatga aggaaactgg cgagtaaata
     6601 gagggtaccg tatccaatac aactcagcta tcggccctta taaaggtgga ttgcgcttcc
     6661 atcctagtgt caatctaagt atcttgaaat ttttggcttt tgaacagatt ttcaagaata
     6721 gtttaaccgg tctgccaatc ggtggaggaa aaggcggaag tgacttcgat cctaaaggaa
     6781 aatctgataa tgagatcatg cgtttttgtc aaagtttcat gctggaattg tcaaaacata
     6841 tcggcccatc gattgatgtt cctgcgggag atatcggtgt aggagctaga gaaatcggct
     6901 atttgttcgg cgaatataaa cgattgaaaa aatatgatac tggtgtgttg acaggtaaac
     6961 ctttggattt ttggggaagt aagatacgta cggaagctac tggttatgga ttagtgtatt
     7021 atgtcaaaca tctattgaac gaagaaaaag attcatttaa tcaaaaaaca gtttttgttt
     7081 ccggaagcgg gaatgtagcc atttatgcaa tcgaaaaagt gcaagagcta ggcgggaaag
     7141 ttgttacatg ttcagattct agcgggtaca tctatgatcc agaaggaata gatgtgaaac
     7201 tattgaaaga agtcaaagaa atcaatagac aacgtttgac ggaatacgca aaccaacgtc
     7261 cttctgctat ttatcatgct ggagaatctg tttggacatt gaaagaaaaa gcggatatcg
     7321 ctttgccatg tgctactcaa aatgaaatag acgaaagctt ggccgaaatc ttagtagaaa
     7381 atgggatcaa aatcgtagca gaaggcgcta atatgccatg tacagtaaaa gctgtttctg
     7441 ttcttcatga agcaggcgtg tggtattgtc caggaaaagc tgctaatgct ggaggagtag
     7501 cagtatctgc tttagaaatg agtcagaacg tccagcgatt gacttgggaa agagagcaag
     7561 tggatgagca gctggatcaa atcatggaaa cgatttacca tacgtgtcgc caaacagcag
     7621 ccgagtacgg cgacgaaaaa aatctgcttc ttggagcaaa tgttgctgga tttgaaaaag
     7681 ttgccaaagc aatggcagca gaaggtttag tttgaaaaat gaaactttct tggaaatatt
     7741 gtcagcattt tgtttatttg cttgaaaaat aataaaaaaa aacgtaaagt attacctgta
     7801 gagtaaacct ataaggagga gaacaaatgg cacacattca ttttgactat tcaaaagtag
     7861 caccgtttgt caacgaacaa gagttagggt acatgcaaag ccaagtaaca gcagcccaca
     7921 acgaattacg ggaaggtact ggcgcaggaa gcgacttccg cggctggatc gatttaccaa
     7981 cgaactatga caaagaagaa tttgcacgta tcaaagaagc agctaaaaaa atccaatctg
     8041 attctgaagt attagttgtt atcggtatcg gtggttctta tttaggcgct cgtgcagcga
     8101 tcgacttctt gaatcacaca ttcttcaatt tattagatag caacacaaga aaagcaccac
     8161 aaatcttctt tgccggaaat tcaatcagct caacatatat tgctgacttg atcgaagtaa
     8221 tcggtgatcg cgacttttca gtaaacgtta tttcaaaatc tggaacaact actgaaccag
     8281 cgattgcgtt ccgtgtattc aaagagcttc ttgttaagaa atatggacaa gaagaagcaa
     8341 acaaacgtat ctacgctaca acagataaag caaaaggtgc agttaaagta gaagcagatg
     8401 cagaaggttg ggaaactttc gtgattcctg atgacatcgg cggacgtttc tctgtattaa
     8461 ctgctgttgg tttgttacca atcgctgtta gtggtgcaga tatcgatgca ttgatgcaag
     8521 gtgccgctga tgcaagcaaa gcatactcaa gcgacaaact agaagaaaac gaagcttacc
     8581 aatacgcagc aatgcgcaac attctttacc gtaaaggcaa agtaactgag ttgttgatca
     8641 actatgaacc aggaatgcaa tacttctcag aatggtggaa acaattgtat ggtgaatctg
     8701 aaggaaaaga ccaaaaaggc atctatcctt caagcgcaaa cttctcaact gatttgcact
     8761 ctttaggaca attcatccaa gaaggacgtc gcaatatttt tgaaacagtt gtgaaggttg
     8821 aaaaacctcg taaatcaatc acaattcctg aacaagcaga agatttagac ggtctaggct
     8881 acttgcaagg aaaagaagtg gacttcgtaa atacaaaagc atttgaagga acattgcttg
     8941 ctcatacaga cggtgacgtg cctaacttgc tagtcaaaat tccagaaatg gatgcttata
     9001 cattgggtta tacaatgtac ttctttgaaa ttgctgtagg tatttcaggt tacttgaatg
     9061 gaatcaaccc attcgaccaa ccaggtgtag aagcttacaa gaaaaacatg ttcgcacttc
     9121 taggcaaacc aggctttgaa gatcttgcta aagaattgaa cgaacgcctg taagataagg
     9181 gtttttcgct agatttaaat aatcagtgat agaaacatgt tcgctttaaa atgaaaactg
     9241 gtacccattt aggtactcaa acatactgca tcgtttattc agaataaggg gctgtgacaa
     9301 gacgtttgtc acagtccctt gtttgtatag aaatcgattg attgccttgc tctttagttt
     9361 gttttaggac tttaagaaca gtgaggctga cttcgaaggt taattctgtt tttttgtttt
     9421 ctagaatcag taagcaaaaa agcactcact tcgagtgctt ttttgcgata tattcttagc
     9481 ttaagatagg cctaattttt cttttacaga tgagggtacc ttatcgctgg taattacttt
     9541 tttctctatg atccgctttt cgcttgcttt caactgcaag atcgttcctt cggggtaagc
     9601 agaaccattg gcagagtcac cagaagtaat gacatcgaaa tctaactgtc ttttttcacc
     9661 gttttcagca taagcatcta cgttgtattt aaaacctctt ccaattactt ccccattatc
     9721 tgctttgata tcagtttctg caggcattgg agctttgact accgcataat aatctttacc
     9781 tacataagta gactgatagt agtcccaacc tttccatcct ataaaagcaa tcaatatgat
     9841 aacgatcaac cctaaaattt ttttcatgaa agatctcctt ttttattttt atta
//
LOCUS       DASHXG010000081         9665 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.085, whole genome shotgun sequence.
ACCESSION   DASHXG010000081 DASHXG010000000
VERSION     DASHXG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.085"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..650)
                     /locus_tag="U2R59_002522"
     CDS             complement(<1..650)
                     /locus_tag="U2R59_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEM8966860.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="U2R59_002523"
     CDS             975..1391
                     /locus_tag="U2R59_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEM8966861.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="U2R59_002524"
     CDS             1388..1858
                     /locus_tag="U2R59_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEM8966862.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="U2R59_002525"
     CDS             1872..2645
                     /locus_tag="U2R59_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8966863.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="U2R59_002526"
     CDS             2659..3471
                     /locus_tag="U2R59_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEM8966864.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="U2R59_002527"
     CDS             3525..4490
                     /locus_tag="U2R59_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8966865.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="U2R59_002528"
     CDS             4606..7329
                     /locus_tag="U2R59_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HEM8966866.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="U2R59_002529"
     CDS             7342..7974
                     /locus_tag="U2R59_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEM8966867.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9665
                     /locus_tag="U2R59_002530"
     CDS             8873..>9665
                     /locus_tag="U2R59_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966868.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3260 a         1477 c         1884 g         3044 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtatt
//
LOCUS       DASHXG010000082         9444 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.086, whole genome shotgun sequence.
ACCESSION   DASHXG010000082 DASHXG010000000
VERSION     DASHXG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.086"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            59..205
                     /locus_tag="U2R59_002531"
                     /pseudo
     CDS             59..205
                     /locus_tag="U2R59_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="U2R59_002532"
     CDS             282..611
                     /locus_tag="U2R59_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8966869.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="U2R59_002533"
     CDS             601..888
                     /locus_tag="U2R59_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8966870.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="U2R59_002534"
     CDS             1174..2031
                     /locus_tag="U2R59_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8966871.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="U2R59_002535"
     CDS             2032..2580
                     /locus_tag="U2R59_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966872.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3473
                     /locus_tag="U2R59_002536"
                     /pseudo
     CDS             2840..3473
                     /locus_tag="U2R59_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3518..4467)
                     /locus_tag="U2R59_002537"
                     /pseudo
     CDS             complement(3518..4467)
                     /locus_tag="U2R59_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            5069..6913
                     /locus_tag="U2R59_002538"
     CDS             5069..6913
                     /locus_tag="U2R59_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8966873.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="U2R59_002539"
     CDS             6969..8435
                     /locus_tag="U2R59_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEM8966874.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="U2R59_002540"
     CDS             8472..9314
                     /locus_tag="U2R59_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8966875.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1443 c         1906 g         2849 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa atct
//
LOCUS       DASHXG010000083         9229 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.087, whole genome shotgun sequence.
ACCESSION   DASHXG010000083 DASHXG010000000
VERSION     DASHXG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.087"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(58..2184)
                     /gene="pnp"
                     /locus_tag="U2R59_002541"
     CDS             complement(58..2184)
                     /gene="pnp"
                     /locus_tag="U2R59_002541"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEM8966876.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(2372..2641)
                     /gene="rpsO"
                     /locus_tag="U2R59_002542"
     CDS             complement(2372..2641)
                     /gene="rpsO"
                     /locus_tag="U2R59_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEM8966877.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            2892..3455
                     /locus_tag="U2R59_002543"
     CDS             2892..3455
                     /locus_tag="U2R59_002543"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEM8966878.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(3708..4229)
                     /locus_tag="U2R59_002544"
     CDS             complement(3708..4229)
                     /locus_tag="U2R59_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEM8966879.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(4232..5074)
                     /locus_tag="U2R59_002545"
     CDS             complement(4232..5074)
                     /locus_tag="U2R59_002545"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEM8966880.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(5067..5792)
                     /locus_tag="U2R59_002546"
     CDS             complement(5067..5792)
                     /locus_tag="U2R59_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HEM8966881.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            5968..6264
                     /locus_tag="U2R59_002547"
     CDS             5968..6264
                     /locus_tag="U2R59_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966882.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            6832..8424
                     /locus_tag="U2R59_002548"
     CDS             6832..8424
                     /locus_tag="U2R59_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8966883.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            8437..9177
                     /locus_tag="U2R59_002549"
     CDS             8437..9177
                     /locus_tag="U2R59_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEM8966884.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         2561 a         1879 c         1831 g         2958 t
ORIGIN      
        1 aattattgtc cccctgtcac cttcacgatc acaagtacat tattcctatg aattaaatta
       61 tttttcttca tttttcgttg aaccatcttc gttcaacatt gcttttcttg acagatttac
      121 gcgtccttgt ttatcgattt cagttacttt cacaaggatc tcatcaccta gtttaacaac
      181 atcttcgact ttattgacac gatcgtttgc taattgggaa atatggacaa gtccatcttt
      241 tcctttgatc aagttgacga atgcaccgaa tttttcgata cggacaactt tccctagata
      301 aacttcacca actttgactt ctttggtcaa atcttcgatg atcttgatag cttttttgat
      361 catttctgca tcagctgaag caatacttac ttttccatct tgatcgatat cgattttcac
      421 accagtttca tcgatgattc cgttgatcgt atcgccgcct ttaccgataa catctttgat
      481 tttagcaggt tcgatctgga tcatttcgat ttttggtgca tattggctta attcttcacg
      541 tggagcagca atcgttgaag tcaattcttc taagatttcc atacgtgctt gttttgcttg
      601 agttaatgct tcagttagga tttgttctgt gattccttga atcttgatat ccatctgtaa
      661 agcagtgata ccatcttttg taccggcaac tttaaagtcc atatcgccaa gatgatcttc
      721 cagcccttgg atatcagtta ggatcgtata gttttcacca tcagaaacaa gtcccatcgc
      781 aataccggcg actggcgctt tgattggtac acctgcatcc atcaatgcta atgtgccagc
      841 acagatactt gcttgggaag aagaaccatt tgattccaat acttctgcta ctaaacggat
      901 cgtataagga aattcttctt ctgaagggat tacttgtgct aacgcacgtt cacctaatgc
      961 gccatgtccg atttcccgac gccctggaga gcctgcacgt cctgtagaac caacagaaaa
     1021 ttgagggaaa ttgtagtggt ggatgaatcg tttgctgact tccaccccta aaccatcaat
     1081 gatttggtgc tctcctagag gtgcgagtgt acaagctgat aaagcttgtg tttgtcctcg
     1141 tgtgaacaaa cctgatccat gtacacgtgg caataagctg acctctgatg acaatggacg
     1201 gatttcatcc aatttacgcc cgtcaggacg gatcttatcg atggtgatca attcacgtac
     1261 gacatctttt tcaagatctt ctgtgatttg tttaacttct ttcaacaagt gatcttcatc
     1321 ttcatgacct gcaaatttct cagcataagc ttcgcggata tcgatcttca cctgctcgat
     1381 attatcttcg cgagcaagtt tttcttcagt cattactgct gctttcattg tagcgtaaga
     1441 agcatcaaag atttcttttt tcaatacttc atcaacttgc agtaaagtca cttccatttt
     1501 ttctttccct actgcttgaa cgatttcttc ttggaaagca actaactctt tgatagcgtc
     1561 aaaaccaaac agcaatgcac caagcatgtc ttcttctgaa acttctttcg cgccgctttc
     1621 aaccatattg atggcttgtt tcgttccggc aacagtcaat tcgatatctg tttgttctgc
     1681 ttgttctact gttggattca agacgtactc gccatttaca cgaccaactt ctacgcctgc
     1741 gattgggccg tcaaatggga tatctgagat tgatagtgct aaagaagaac ctagcattgc
     1801 tgccatagct ggcgagcagt ctgtttctac actcatcacg atgttcgtta cttggacttc
     1861 attacggaag ccttctgcaa acatcgggcg aattggacgg tcgatcaaac gggcagtcaa
     1921 tgttgcttcc gtacttggac ggccttctcg tttgatgaaa cctccaggga ttttccctgc
     1981 tgcatacatt ttttcttcat aattgatcgt taatgggaaa aagtctgtat cttttgcttc
     2041 tttagaggcc acagctgcac ttaagactac tgtatctcca taacggacta aaacggctcc
     2101 gtttgcttgt tttgctagct gaccgacttc gatttgtaag ggacggccgc cccatgtcgt
     2161 tttgaatact tgtttttctg acataacttc tccttttcct tctcgtgaaa gcaagacgct
     2221 actaaacaaa tgaaaactgc cgaaagccgt cttttgagca gctttcattt ggttagtagg
     2281 agtccatcta gcttgatcac ggaattttac ttaattgata tacgagtaaa aaaagtgaga
     2341 ttcatgtgaa tcccactctt tttgactaaa attaacgacg caagcctaaa cgtttgatca
     2401 attcgcggta acgttgaacg tcagttttac gtaagtaagc taacaagtta cggcggtgac
     2461 caactttttt cattaggccg cggtatgaat gatggtcttt tttgtgcacg cgtgcatgtt
     2521 cattcaagtg gttgatttct tcagttaata cagcgatttg tacttctgga gaaccagtat
     2581 ccccttcatg gcgagcgtat tcgttgatga tttcattctt gcgttctttt gaaattgcca
     2641 tttctttcac ctctttcgat tattcccctg cgactgagta aaacgttggt gattcgctta
     2701 accaagtggc aggtcatgtg cctagagcac acagctatac tttacctgaa accgggttga
     2761 aaatcaagta gttaatcatt aagaaaaggt agttttcaaa caatcttact actacttttc
     2821 catttttgtg gtaaactata atgcgaaaat agacttgaaa cacagtcttt taagaaaggg
     2881 gtacatattc catgattaca atggatgata tcattcgtga aggaaatccg accttacgcg
     2941 aagttgcaaa agaagtttct cttccattaa gcgaagaaga tatctcttta ggaaaagaga
     3001 tgcttgagtt cttaaaaaac agccaagatc caatcaaagc tgaagaacta cacttacgag
     3061 gcggtgttgg cttagctgct cctcaattag atatttctaa aagaatcatt gctgttcacg
     3121 taccaagtcc tgacccagag gcagatggac cttctctaag tactgttatg tataatccta
     3181 aaattttgag ccattctgtt caagatgctt gtttagggga aggtgaaggc tgtttatctg
     3241 ttgatcgaga agtaccagga tatgttgttc gccatgccaa aatcactgtg tcttattatg
     3301 atatgaatgg tgaaaaacac aagattcgtt tgaagaatta tgaatcgatc gtcgttcaac
     3361 atgaaatcga ccatatcaac ggtgtgatgt tctatgacca catcaacgat caaaatccat
     3421 ttgcactaaa agaaggcgta ttggtgatcg agtagagaat tggcaggttc cttcgatact
     3481 atgctacaag aaagctttat aaaaaagggg agtgctcaaa agctgcactt ccctttttta
     3541 tgtttctcca ctaatcgaaa tttagataga catctagaaa tcgcaattcc aaaaaattct
     3601 gtgtattgga tacgcatctt ttcttatttt ttcttatttc ttccatatgg gtgtttatct
     3661 cagagatgat agaatagttt ctaggataaa aagtagcagc tacgatgtta tccttcgtag
     3721 aggattcctg cttcagctag tttttgtttg atgtttttca gcatatgctt ttctgggtag
     3781 cggatcgtat gcagatggat gccgcctgtt aattcggata acaaagtagc attacttttt
     3841 tgataacgtc tcataaagga atcgatatct tgtggcgttt tgatgtgcaa agttcctgct
     3901 aactcaccgt aaaggggatg ttccacaatt acatcaatga tttcaccacc attttcaacg
     3961 attagtctca gttcttcttc tgtttgatct tttccatgct ggacagcgat tttactgatg
     4021 tgcccagtat tggtttcttc tgtttcgagg atataacctc ttgctgttgc cacgatactt
     4081 ttacctgcag ctcgtagtaa agcaatatcg cctacaatga tctgacggct gactccaaaa
     4141 gttttcgcaa acttgctagc actcactggt ttttctgtat ttgccaaggt ttgcatgatt
     4201 tgttttcgcc gtgtctctcc ttcgatcaca cttattcctc cttcattttg ttttggtatt
     4261 cgcgcgagtg tttcatcaaa tcaacatacg tgtctgttat tgtttcctta tatcccttat
     4321 ttttcagcag actaacaact ttatccaata cttgctgctc tctttttgca tcataaactg
     4381 cttggttttc ttcttttttc acttgtccta ttttagttac cgtatccatt cttttttcta
     4441 ataaagcaac caactctcga tcgatcatat cgatcttatg acgtaatgtt tcaagagact
     4501 cttctgttag ttcttcctct actgtcttga tgatacgagc aggatttcct gcaatcacta
     4561 cattgtcggg aaaagatttg gtcacaaccg aacctgcgcc gactactacg ttgtccccta
     4621 gagtgacacc cggcgtgacg ataactcctc cgcctaacca aacattatta ccgattttaa
     4681 tgggttttgc gtactccaga ccgctgttac gtttcactgg atgtagtgga tgcgtcgccg
     4741 tgtaaagctg gacattcgga gcgaacatgc agttatcacc gatttcaatc gtgctgacat
     4801 ctaaaaatgt acaattgaaa tttgcataaa aattctcccc aacaaatata ttatatccgt
     4861 aatcaaaatt gataactggc tccatataga tttttttccc tgtacggcca aaagtctctt
     4921 tcaacaattg ggatcgcagt tccgctgatt ctgcttggtt gatgatttgg ctttgacttc
     4981 ttgcaaacat acggtcggca accagctcag gatcattggc aaaataaagc tcgcctgcaa
     5041 tcattttttc tttttcggtt ttgaattcag tcataatctg ctcctaattc ttgtattttt
     5101 ttgaaaacaa ccgctccgtc ttcttgaata aacgtataag gctccgctaa ataaacaggc
     5161 gtttgattga ttactaagat tttggctgac ggctggcgaa actgtaccag atcacaaaac
     5221 ggatgaactt gaaaactcgt tccaacaatg acgatcagct ctgcttggct gacggcataa
     5281 gccgcctgct ccatgactcc atcttgaaac ccttcaccat ataacacgat gtctgggcgt
     5341 atttgtcctc cgcatgcttg atgtttgtcg ctgtgaagat attctttcca gtctaccgtt
     5401 tgttgacatt ttcgacaatg acattgatac agactcccat gaaaattgac gagttgcggg
     5461 cttttagcct ttgcgtgcaa accgtcgatg ttttgggaaa caacccaaac atttttttct
     5521 ttcgctagat gtgctatttc caaatgaatg atattgggtt ttgcttcagg atgataaatc
     5581 tttttgacaa attgatagaa tttatccggt tcattcacca ttgcttgatg actcagcaag
     5641 tattccggct gctccatccc gtggtagatt cctgacaaag atcgatagtc tggcactcca
     5701 gaaggtgtgg atacccctgc accggtcaaa aatgtaattt gctgataagc taatatctct
     5761 tttgctgctt cgtctactgt taattgtttc atgttttgtc acctcacttt ccattatagc
     5821 ccatactcga acaaatttat tgttgaaaag tcagaaaaat gggaataaaa aagtgttatg
     5881 ggcatttgag caatttatca caatgttcac tgacaaaaga atgaaaacgt gttacaatac
     5941 tgctgtataa aagtgaggtg aatcgatatg ttaccattct ttatttattg gggcgttatt
     6001 ctggcttgta tcgcctggtt agcgttaagc gtttatttct ctgtttttta tcttgtacgc
     6061 aaagaaaatg gaaatctttg ggcttttgct ttattcaacg tgattgccgc aattgtttta
     6121 gccattacat tagccgtata tcgaacatgg ggctggggaa tcacccaata ctcaagtttg
     6181 atttatctaa tattagccat ttatggcgtc gttgttcttt tgcaagcgat cctaggacgt
     6241 gagccaaaga aagcggcagc ttaaatgatc gagatggaac tggacacagg aaattttctg
     6301 ttctagttct ttttttattg tattacatac atttttgtgt ataattatac tatcgtttgc
     6361 aatggataga tgattcacat tttgattgtt ttttcggtaa aagtaaagat ttctatattt
     6421 atcagtattt tttcaaaaac cagcagttat agattgacaa agcctctcga gtatcgtaaa
     6481 ctttttttgt ataaataact gaatacgaga tgcctcaatc aatgaggtag aggtcgcgag
     6541 aatcattaac cctgtggagt gaagcaaaca tggagaagca ggaataggga ggatcgccga
     6601 aatgtgcact tttttgcttg gagtgtatgt tgggacgcaa gttaagagct tgcggactgt
     6661 cttagcagtg atgctaagtt gcgctatgtt ttgtgagagg tttatcacct tatggaattt
     6721 tagcggcctt tttatatcta taaatcggtc gctttttatt ttttcagata aagctttacc
     6781 gcatttcatc tagaccgctc gtgtatcata taatcagaaa gggagaaaaa aatgaaaaaa
     6841 aatatggttt cagttgccgt actatttgct tttgtcttct cactattcag tgtgggatct
     6901 ctggcaaatg cagatgaaaa aacaccgagc gatgagtttc gcgtaggtat ggaggctggg
     6961 tatgcaccct tcaactggtc tcaacaaaca gatgagaata atgccttgcc aattcaaggc
     7021 caaaatagtt acgccggcgg ttatgatgtt caaatcgcta aaaaagtagc agatggttta
     7081 gggaaaaaat tagtcatcgt ccaaacgaaa tgggatggtc tggctcctgc ccttcaatca
     7141 ggcaagatcg acgcgatcat cgccggaatg agccctactg ctgaacgacg aaaagaaatt
     7201 gattttaccg atccttatta cgaatcacaa ttagtagtag tagttcaaaa agatagcaaa
     7261 tatgcaaaag caaaaagttt agcagatctt tctggagcaa agatcactgc tcagttaaat
     7321 acattccact atactgtgat cgatcagata ccagatgtgc agaaacaaca agcaatggat
     7381 aatttctcag caatgagaac agctttagct tctggaatga tcgatggtta tgtcagcgaa
     7441 cgtccggaag gtgtaacggc aactagtgtg aacaaagact tggaaatgct tgaattcagc
     7501 ggtgcagatg gcttccagac aaacccggaa gatgttcaga tttctgttgg tatgcgtaaa
     7561 ggcgacccgg atatccaaaa agtaaaccag attctttctg gcatctctaa cgatgaacga
     7621 accaaaatta tggaccaagc agtcaaagat cagcctgctg caactgatag tgaagaaaaa
     7681 cctggcatca tttctgattt cactacgatt tggaaacaat acggcaatat gttcttacga
     7741 ggtgctggac ttaccttgtt catcgcattg atcgggacag ttgtcggtac tacacttgga
     7801 ttactgattg gtgtcttccg ttcggtacct gaatcaggaa atgcactgac tcgcttcttc
     7861 caaaaaatcg gaaatgcact tctttctatc tatgtcgaag tattccgcgg aacaccgatg
     7921 atggtacaag caatggtcat cttctacggt ctggcactcg cttttggcat ttcattgaac
     7981 cgaacgattg ccgctttgtt tattgtctct ctcaatactg gagcttacat gacagagatc
     8041 gttcgtgggg ggatttttgc agtagatgaa gggcagttcg aagctgcgca agccattggt
     8101 atgacccatg gccaaacgat gagaaaagtt gttattccac aagttttacg gaatatcttg
     8161 ccagcaacag gaaatgagtt tgttatcaat atcaaagata cagcagtttt aagtgtaatc
     8221 ggcgtagctg atttgttctt ccaaggaaac tctgcttccg gtgcgaattt ccaattcttc
     8281 caaacattta cgatcgtcgg gatcatctac ttagtcatga cctttacgat caccagaatc
     8341 ctgcgggcgg tagaaaagaa aatcgatggt ccttcagctt ataccaagct tgaagaaatc
     8401 gacaattcaa atttgcagga ataaggagga agaatcatga atgaaaaaat tattgaaatc
     8461 aaacatctaa gaaaaagctt cggtgaaaat gaagtattga aagatatcag cgtaacagtc
     8521 aataaaggtg aagttgtgac gatcatcggt tcttccggtt ctggtaaatc tactttcttg
     8581 cgctgtatca atttactgga aaaaccaaca ggcggcgaga tcatttataa tggagaaaat
     8641 gtattagctc ctaaatataa tttacctaaa tatcgaacga atctaggtat ggttttccaa
     8701 tccttcaacc tgttcaacaa tatgaatgtc ttggaaaact gtatgtctgg tcaaacaact
     8761 gtcctgaaac gagataaaga aactgccaaa aaagtagcaa tcgaaaatct ggaaaaagtt
     8821 ggtatggatc gttatatcga agccaaacca gcacaattat ctggtggaca gaaacagcgt
     8881 gtcgcaattg ctcgggcatt atcaatgaat ccagatgtat tgctattcga cgaacctact
     8941 tcggcgttag accctgaaat ggttggcgaa gtgcttaata cgatcaaaga cttagcacat
     9001 actggcttga caatgcttat cgtgacgcat gagatggaat ttgcaaaaga tgtatctgac
     9061 cgtgtcattt ttatggataa aggtgtgatt gcagaagaag gtacaccaga agatatcttt
     9121 gtccatccga aagaagaacg tacaaaagaa ttcctttcac gtattttaaa tgcttaggat
     9181 caatagctga ttgggacaaa gagctgcggt gtttaccgca gttcttttt
//
LOCUS       DASHXG010000084         8863 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.088, whole genome shotgun sequence.
ACCESSION   DASHXG010000084 DASHXG010000000
VERSION     DASHXG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.088"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            90..1424
                     /gene="dnaA"
                     /locus_tag="U2R59_002550"
     CDS             90..1424
                     /gene="dnaA"
                     /locus_tag="U2R59_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEM8966885.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            1622..2752
                     /gene="dnaN"
                     /locus_tag="U2R59_002551"
     CDS             1622..2752
                     /gene="dnaN"
                     /locus_tag="U2R59_002551"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEM8966886.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            2981..3223
                     /gene="yaaA"
                     /locus_tag="U2R59_002552"
     CDS             2981..3223
                     /gene="yaaA"
                     /locus_tag="U2R59_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEM8966887.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            3210..4334
                     /gene="recF"
                     /locus_tag="U2R59_002553"
     CDS             3210..4334
                     /gene="recF"
                     /locus_tag="U2R59_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEM8966888.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            4331..6277
                     /gene="gyrB"
                     /locus_tag="U2R59_002554"
     CDS             4331..6277
                     /gene="gyrB"
                     /locus_tag="U2R59_002554"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEM8966889.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            6297..8768
                     /gene="gyrA"
                     /locus_tag="U2R59_002555"
     CDS             6297..8768
                     /gene="gyrA"
                     /locus_tag="U2R59_002555"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEM8966890.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
BASE COUNT         2953 a         1606 c         1923 g         2381 t
ORIGIN      
        1 tttttttctt cggtttctgt ggaaaactat tgaaaaaaat gctaaattag tactagttat
       61 tcacttttta atgaaggagg aggccttata tggtatccct cgatgcttta tggaatgaat
      121 taaaagcaac ataccaaaag gatttatcgc ctgctagcta taatacatgg atcgaaacag
      181 cgaaccctcg aacccttgat caaaaccagc tcgttgttga ggttcctagc aagattcata
      241 aagaatattg ggaaaaaaac ctggcgacaa aaatcgttga agtcggttat atgttatcag
      301 gaaatgagat tatccctcgc tttattactg gcgaagaagc agagcaagaa gaagttatag
      361 aagaaaaaaa tccaaaagtt gtggcaccta gtccgctaaa aaaagccatg ctgaacccta
      421 aatatacctt tgatacgttt gtcattggta aaggaaacca gatggctcat gcagcagcgc
      481 tcgttgtagc agaagatcca ggttctattt ataacccgct cttcttttat ggaggcgtgg
      541 gacttggtaa gactcacttg atgcatgcaa ttggtcatca aatgctgcaa agtcagccta
      601 atgccaaagt aaaatatgta agcagtgaaa cttttgctaa tgatttcatc aattcgatcc
      661 aaaacaaaac agcagaagag ttccgtcaag aatatcgaaa tgttgattta ctgctagtgg
      721 atgacattca attttttgca gaaaaagaag ctacgcaaga agagtttttc catactttca
      781 atgccttgta caatgaaggg aaacaaatcg tactaaccag tgatcggttg ccaaacgaga
      841 ttccgaaact gcaagaacgc ctcgtttctc gctttgcatg ggggctgtct gttgatatta
      901 caccgccgga tcttgaaaca agaacagcga ttttacgtaa aaaagcggcg gctgaacgtc
      961 tagagatccc agatgacaca ctaagctaca tcgcaggaca aattgattct aacattcgtg
     1021 aattagaagg tgcgcttgtt cgagtgcaag cttttgctgc gatgaatagt gaagatattt
     1081 cgactagtct agctgcagac gcactgaaaa cgttaaaatc aggaaaagga catcctcaat
     1141 tgtcaatcct gcagatccaa gaagaagtgg caaagtatta tcacatccaa ttgaaagata
     1201 tcaaaggaaa gaaacgcgtc aaatctattg ttgttcctag acaaatcgct atgtatttgg
     1261 cacgtgagct cacagataat tctttaccga aaatcggagc tgaattcggt ggcaaggatc
     1321 atacaacggt tatccatgct catgaaaaaa tccagcagct gatggattct agtgtcagta
     1381 tgcaaaatga agtatcagaa atcaaaaact ttttactaaa ttaatttgtc gattctatca
     1441 actgaaaata gcatgtggat aaaagaaaaa aacgttcaaa agttatgcac actttttcca
     1501 cagctgtttt ttcgtttctc tcttacgttt tttgagtttt ccacagaatc aacatgccct
     1561 attactttta ttattctttt taactaataa taaataaaca aacattcaaa ggagatacat
     1621 catgaaagtt actttaaacc gagctagctt tatgcaggaa ttgcaaactg ttcaacgagc
     1681 tatttcaagc aaaaccacga tccctatttt gacaggtgta aaaatcacac tgacacaaga
     1741 aggtttgact ttgacgggga gcaacgctga tatatcaatt gaaacttttt tgtctgttga
     1801 aaacgaaaaa gcaaatatgc aaatcgaatc tactggttcc attgttttac aagcacgttt
     1861 ctttagcgaa atcattcgga gacttcctga agaaacattt actttagaag ttttagaaaa
     1921 taaacaagta gcgattactt ctggaaaagc gaattttatc gtaaatggat tagatgcaga
     1981 taactatcct catcttcctg ttgtcgaaag ccataaccag atgaaattac ctgtacacgt
     2041 attgactaaa ctaatcaacg aaacagtttt tgctgtctca caacatgaga gtcgtccaat
     2101 cttgacaggt gtgcatttca ttttatctga taattcttta ttggctgtag ctactgattc
     2161 tcaccgtcta agtcaacgcg tgattccagt agaacaagcg gctgatcatt ttgatattgt
     2221 tattcctgga aaaagtttga tcgaattatc tcgctcatta acaaatgaag aagaaatcgt
     2281 cgaaatcagc attatggaaa accaagtgtt gttcaaaaca gaaacgatgt atttctattc
     2341 ccgtttgcta gaaggaaact atcctgatac caatcgtttg attccttcaa gttttaatac
     2401 agaggttgaa ttttctgttc ctagcttttt agcggcgatc gaacgggctt ctttactttc
     2461 tcatgaaggc cgtaacaaca tcgttcgttt atctattcgt ccagatgcgg ttgttttata
     2521 cggaaattcg ccagaaatcg ggaaagtaga agaaagcttg agttatacag caagcagtgg
     2581 cgatccatta gatatttctt tcaatccgga ttatatgaaa gcagcgttgc gtgcatttgg
     2641 agatatgagc atcaaagtga aatttatctc tgctattcgt ccatttacat tggaaccaac
     2701 ggaagatggc gttcaattta ttcagctgat tactcctgta cgtacaaatt aacaatgatt
     2761 ttcattgttc ttgaaaattt aattgaaaag aaatagaaaa aataaaattt taaacagaag
     2821 gccctaaaat ctcttttaag gctttctgtt tatttttgtt taaatcacct tttttagatt
     2881 aaatcgtctt atatggaaaa atatatggat aaatttgttt tattgcgaaa aaaaaggtat
     2941 aatagagtat acttttaata atgaaaatga gggatgggca ttgaaacaac aagtcattct
     3001 aaatacggaa ttcatgacgt tgggccaaat gttgaaagaa gtcacagtta tcggtagtgg
     3061 cggacaagca aaatggtatt tggcagaaaa cactgtgtta gtcgatggcg aaccagaaaa
     3121 tcgtcgtgga cgcaaacttt atcccggcat gatggttgaa gttccagaag taggaacttt
     3181 ttttatggta aaaaaaggaa acgacgataa tgaggctgaa taagctgtat ttaaaaaatt
     3241 atcgaaatta cgaagagctg aacatcgaat tttccaagaa cctcgtcatc tttttaggag
     3301 aaaatgcgca aggaaaaacg aatcttttgg aaagtatcta cgtattagct atgacgcgaa
     3361 gtcatcggac aagtagtgag caggaattga ttggctggac tgacgatcag gcgatgattc
     3421 aaggagagat cacaaaaggt tcatccactc ttccattaga aatcttatta tctaaaaaag
     3481 gccgaaaaac caagatcaac catatcgaac aaaaaaagtt aagtacttac gtgggacaaa
     3541 tgaatgtcat tttatttgca ccagaagatc tttctttagt aaaaggcagc ccgcagatca
     3601 ggcggaagtt tttagatatg gaattaggcc agatcaatcc aatctatctt tatgatcttg
     3661 tccaatacca agcaattttg aaacaaagaa accagtattt aaagcaattg aatgaaaaaa
     3721 aacaaactga tttgctttat ttggatattt tgtccgaaca actagcagcg tttggcagca
     3781 aagtattgaa agcaagagca cagttcgtca agcgattgga gttttgggct aattctttgc
     3841 atcagcaaat cacccatcaa aaagagcagc tggaaatcga gtatctcacc gcagtcgatt
     3901 ctttagaaac acatacgcaa gagcaaatcc aagaacaatt tctcgcactt ttgaaccaaa
     3961 ataaaaagaa agaccttttt cggggaacaa cgacagttgg tcctcatcgt gacgatcttt
     4021 ccttttttat taatcagaaa aatgtgcaga cttatggatc gcaaggacag caaagaacaa
     4081 ctgcactaag tgtcaaatta gcagaaatcg atttgattaa agaagagacg ggggaatatc
     4141 caatcctttt gttagatgat gtgatgagcg agctggatga tagtcgtcaa ctccatctgc
     4201 tagaaacaat cgaaggaaaa gttcaaacgt tcttaacaac aacgacactt gaccatgtaa
     4261 aaaataaaat gactgttgaa cctgagattt tttatgttca acaagggaaa ctaaaaggag
     4321 aagaaactga atgacagaag aaagaagttt agtagaacgc gctaaagagt atgatgccag
     4381 tcagattcaa gtacttgaag gacttgaagc cgttcgtaaa cgacctggca tgtatatcgg
     4441 ttcgactagt tctgagggtc tgcatcacct tgtttgggaa attgtcgata attcgatcga
     4501 tgaagtatta gcaggttttg caacgaaaat ccatgtgatt attgaaaaag acaacagtat
     4561 caccgttatt gacgacggtc gggggatacc tgtagatatc caggcaaaaa ctggacgtcc
     4621 tgcagttgaa acggtcttta ctgttttaca tgctggagga aaattcggcg gtggtgggta
     4681 caaagtttct ggtggacttc acggagtagg atcttctgtt gttaacgcgc tttctacaca
     4741 gcttgatgtc aaagtataca aagaaggaaa tgtgtactat caagaatatc gtcgtggagc
     4801 tgtagtggac gacttaaaga ttatcgaaca aacggatcgc catggaacaa cggttcactt
     4861 tacgccagac cctgaaattt ttacagagac aactgagttt gatttttcaa aattggctac
     4921 ccggatccgt gaacttgctt tcttgaaccg cgggatgcgt atatcgattg aagacaaacg
     4981 agaagaagaa ccagtcatca atgaatacca ttatgacggc gggattaaaa gttatgtcga
     5041 atacttgaat gcaaacaaaa ccgtgatttt tccagaacct gtatatttgg aaggtgaaca
     5101 gcaagatatc gcagttgaag tctctatgca atatacagac ggctaccatt ccaatatcat
     5161 gagttttgcc aacaatatcc atacgtatga aggcggaaca catgaatcag gattcaagac
     5221 tgctttaact cgtgtgataa atgattatgc ccgaaaacaa aagctgatga aagaaaatga
     5281 cgacaacttg accggtgaag acgtgcgaga aggattgaca gctgttattt ctatcaagca
     5341 tcctgaccct caattcgaag gacaaacaaa aacaaaattg ggcaattccg aagtacggac
     5401 agtcactgat cggttattta gcgaacattt catgaaattc ttgctggaaa acccaagtgt
     5461 gggccgtcaa attgttgaaa aaggattact agcttccaga gctcgtctag cagcgaaacg
     5521 tgcgcgtgaa gtaacgagac gtaaaggtgc tttagagatt agtaatctgc caggaaaatt
     5581 agcggactgc tctagcaacg atcctgaaaa atgcgaattg ttcatcgtcg aaggagattc
     5641 ggccggcgga tcagctaagc aaggtcgtaa tcgagagttt caagccatct tgcctattcg
     5701 tgggaaaatc ttgaatgttg aaaaagcaag catggacaag atcttggcaa atgaagagat
     5761 ccggtcttta tttactgcta tgggtacagg gtttggagaa gattttgatg tatcgaaagc
     5821 tcgctaccac aaattagtta tcatgactga tgccgatgtc gacggcgcgc atatccgtac
     5881 attgctgctg actctttttt atcgttacat gcgtcctatt gttgaagctg gatacgtcta
     5941 tattgctcag ccacctttat acggggtaaa acaagggaag aatattacgt atgtacaacc
     6001 aggaaaaaat gcagaagaag agttgaaaca agtcgttgct tcacttcctg cctcaccaaa
     6061 accaagcgtt cagcgttata aaggacttgg agaaatggat gatcatcaac tatgggaaac
     6121 aactatggac ccaagcaatc ggatgatggc ccgcgtcagt gtggacgatg ctattgcagc
     6181 agatcagata tttgaaatgt tgatggggga tcgagtagaa ccccgtcgtg cattcatcga
     6241 ggaaaatgca cactatgtga agaacttaga tatttaatca tgaaggagga aaaagaatga
     6301 gtgaagaaat cagagaaaac atccatgatg tcaatctaac cagcgaaatg aaagactcct
     6361 tcatcgatta tgcgatgagt gttattgtcg cacgtgcact tcctgatgtc agagatggtc
     6421 tgaaacccgt tcatcgccgt attttatacg gcatgaacga attaggtgta acaccggata
     6481 aagcccataa aaaatctgcc agaatcgtcg gagatgtcat gggtaaatac catcctcatg
     6541 gagactatgc gatctatgag tcaatggtac ggatggcaca gccattcagc taccgttata
     6601 tgctagtgga tggtcatgga aactttggtt ctgttgacgg tgacggtgcc gccgctatgc
     6661 gttataccga agcacggatg agcaaaatcg ctacagaaat gctgcgtgat atcaataaga
     6721 acactgttga tttccaaagc aactatgatg atacagaaaa agaaccagtt gtactacctg
     6781 ctcgcttccc gaatctttta gtgaacggaa caacggggat cgccgtaggt atggccacga
     6841 atatcccacc tcataacttg tctgaggtag tagcggctat cgatttgctg atggataatc
     6901 ctgatgtgac gaccaatgaa ttgatggaag tattacctgg accagatttt ccaacaggtg
     6961 gtttggttat gggaaaatca ggaatccgaa gagcgtatga aacaggtaag ggttctatta
     7021 ccgtacgtgc aaaagttgag attactgaga tgccaaatgg taaagaacgg atcatcgtga
     7081 cagaattgcc ttatatggtc aataaagcaa aattgatcga acggatttct gaactgcaca
     7141 gagacaagcg tatcgaaggg atcacagatt tgcgggacga atcttcccgt gaaggtatgc
     7201 ggatcgtcat tgacatccgt cgtgacgcca gcgcatctgt tatcttgaat aacttatata
     7261 aattgacatc cttgcaaaat tcatttggat tcaatatgtt ggcgatcgaa aaaggtgtgc
     7321 cgaaagtttt gagcttgaaa caaattcttg aaaactatat cgaacatcag cgcgaagtca
     7381 tcacaagacg gacagtcttt gaaaaagaaa aagcagaagc aagggcacac attttagaag
     7441 gtttgcgtat tgctttggat catatcgatg aaatcattgc gattatccgc gggtctaaat
     7501 cagatgacga agcaaaagcg acgatgatcg aacggttcga tttatccgat cgccagtctc
     7561 aagctatttt agatatgcgt ttacgccgat tgaccggttt ggaacgggaa aaaatcgaaa
     7621 atgaatacca agaactctta aaactgattg aagatttaac tgacattctg gcaagaccag
     7681 aacgtgttac agaaatcatc aagaatgaat tagcagactt gaatcaacga tttggtgata
     7741 aacgacgcac agaattacta gtcggtgagg tcttaagtct ggaagatgaa gatttaatcg
     7801 aagaagaaga aatcgttatt acattgacaa acaatggtta catcaaacgt ttggcaaata
     7861 atgaattcag agctcaacga aggggtggac gtggtgtcca aggaatgggt atccacaatg
     7921 acgacttcgt caaaaatctg gtttcttgtt ctacccatga tacattgtta ttctttacga
     7981 ataacggaaa agtgtatcgg gcaaaaggat acgaaattcc agaatacggg cgcacagcca
     8041 aaggaatacc aattatcaat ttactaggta tcgattcgag tgaaagcatc caggcaatca
     8101 ttgcggtgac gggagaagca gaagaaggcc actatctctt ctttacgacg cgtcaaggta
     8161 cagtaaaacg tacttctgtc actgcttttg ctaacatccg aagtaatggt ctgatcgcaa
     8221 ttggtttgaa agaagacgat gagctcgtca atgtgctact gacagatggt caatctaata
     8281 tcattattgg aacacataac ggctactctg tcactttcaa agaagaagca gtccgcgata
     8341 tgggacgtac agcttccggg gttagaggaa tacgcctgcg tgaggaagat tatgtcgttg
     8401 gggcagcctt aatgaaggaa gatcaagaag tattagtgat cacagaaaaa ggttacggaa
     8461 aacggacaaa agtatcggaa tatccagtga aaggccgcgg aggtaaaggg atcaaaacgg
     8521 cgaacatcac tgaaaaaaat ggtccactag ctggattgac cactgtttct ggagatgaag
     8581 acatcatgct gattacagat aaaggtgtca ttatccgttt caacgtatcg actgtttctc
     8641 aaactggacg ttcaacatta ggcgtacgtt tgatgaagat ggaagctgat acgaaagttg
     8701 tcacgatggc agcagtcgaa ccagaagctg cagaacaaac agttgaagaa caaggatcag
     8761 aagaatagcc atcaagacta attgtgtaag ctagcaagaa tgaccgatta aaaaatctgg
     8821 ttattccggc tctttgtcaa atgatgttgg taaagagaaa tct
//
LOCUS       DASHXG010000085         8614 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.089, whole genome shotgun sequence.
ACCESSION   DASHXG010000085 DASHXG010000000
VERSION     DASHXG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.089"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(83..967)
                     /locus_tag="U2R59_002556"
     CDS             complement(83..967)
                     /locus_tag="U2R59_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEM8966891.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1062..1499)
                     /locus_tag="U2R59_002557"
     CDS             complement(1062..1499)
                     /locus_tag="U2R59_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966892.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(1716..2627)
                     /locus_tag="U2R59_002558"
     CDS             complement(1716..2627)
                     /locus_tag="U2R59_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HEM8966893.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3084..3512)
                     /locus_tag="U2R59_002559"
     CDS             complement(3084..3512)
                     /locus_tag="U2R59_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966894.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(3540..4178)
                     /locus_tag="U2R59_002560"
     CDS             complement(3540..4178)
                     /locus_tag="U2R59_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8966895.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(4182..6164)
                     /locus_tag="U2R59_002561"
     CDS             complement(4182..6164)
                     /locus_tag="U2R59_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEM8966896.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6344..7009
                     /locus_tag="U2R59_002562"
     CDS             6344..7009
                     /locus_tag="U2R59_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8966897.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            8340..>8614
                     /locus_tag="U2R59_002563"
     CDS             8340..>8614
                     /locus_tag="U2R59_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HEM8966898.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRW"
BASE COUNT         2748 a         1621 c         1321 g         2924 t
ORIGIN      
        1 ggctgtgaca aaagtcttgt cacagtccct tatcccgaac aagcggtgtt ctcccgccaa
       61 ctcctcggtc acaacctcca ttttaacaat aaacctgtaa atgtgagggc aatactttga
      121 ttgtcacagg taatttatcc ccttcatctc catcaacatt cgtcgtcaat tcttcctcat
      181 cagctaatga cacaactaat tgctcacaag taaggtaggc tagatttttc gtagattcat
      241 ctactccttt taataggtct ggcaatgttt taagcgtatc gatcaaagaa gaatctttta
      301 aataaaccaa atggagctta ccatcatcca cttttgcatt tggaagtaat gtttcaaaac
      361 cgccgactga gttagttagt cctatcagca aggtactgct ctcaatttct tccttctttc
      421 catcaacttc tacgtgaaac gagtaggatt gtgtggaagc taactgtttg attcctgaca
      481 tgaaataagc tagttttcca aatttcgtct tcttctccgc atctacatca ttgattgatt
      541 cagggataga gccaattgcg acgacattca taaaatagtc gtcatttatt tttccaatat
      601 ccaatggctt gactgattca atcgaaaaat gattgatcgc ttcctcaggt tctagcggta
      661 tccctaatgc tcgagccaag tcattcaccg tacccaatgg gaaaaatccg aaatttggcc
      721 gatgttcttg ttcagcgatt ccactgattc cttcgttgac tgttccatct ccgcccatga
      781 caaacacact atgataccct tccgtagccg cttcgcgagt aaagtttttt gcatcccctg
      841 ctttttttgt atgcaagacg accacttcat caaacaccga ttccaatttt gctatcgcta
      901 attgctcaaa ttcctttgct tgttcaccgc ctgaactggg gtttaccact aataaaactt
      961 ttttcatcac tttctttccc ttctgattga tttctttaat ataacgatag cataaagaaa
     1021 aaaattaggc tgtgatgaag tactgttcat gaaacattca tttatttttt gacaagataa
     1081 aacatccata ctatgaaact gaggaaaatt aaaacaatga tataggaaat aaaagaaaat
     1141 gataggcatt gtatacctaa taaagtaaaa atcttaggtg gcagataaaa acacaaaaat
     1201 agcaagagaa tgtaatagcg tttcttccac tttttgttat cagaccttat agcgatcaga
     1261 ggaataccaa atgcataact gaaaaactct tgatgtactg ttaatatgtc acggccttga
     1321 ataataaatg cgacaatccc cgctataatt agtgtgccta acaccaaaac ggaaaattga
     1381 tgaatatatt ttatatacaa atgatccatt gtacttcctg cctttttatt tgtgagaaaa
     1441 acaaatccgt atacgtgaat aacttctaga aataaaagaa atttgcaaaa ccactccatt
     1501 tatctacttc tacgtgcatt ttttgatatt gttttcttta tttaagatta tacagaaaaa
     1561 tatctagggt cgctggattc taagtaaaaa aaatttttaa aataaaaaga actaaatcaa
     1621 gtagtaatta aactactgtt gatttagttc taataaaaag atttagatga acagttttat
     1681 tgatttaaat agttcatatt ttttatttat accgcttatt tactacttgc tgtactagaa
     1741 tctgaagtga atgtactcaa aacattttca aagtctttgt ctttgatttt tacattagcg
     1801 tctttcaata cttcgccaat tactttattc tggaaggtac tgtcacttaa ttttgtgtct
     1861 gttgcaattt ctttcaattc ttttttgtat ttatccatgt cgttgccttt gttttggttt
     1921 ttcaccattt taaccacata atattccgta gtataagttg aagcattggt agaagtgatc
     1981 acatcagaaa cttgaccatc tttcaactta aaggctgctt ctttgacttc tgccggaacc
     2041 gttgtagtag tggaatcaaa tttcactttt ccgccatctt cttttgtcgt agtatcagtt
     2101 gacttgtctt tggctaattt agagaaatcg tctcccttat cagcagcttt cttcacatct
     2161 tttgcatcat cttcacttgc tacttggata atttgagctt ccacttctgg atggaaagat
     2221 tcccaagccg tttttaaatc ttcatcggtc aatttgatat gtttctttag accttcttga
     2281 aaggctagac tttgtttgat actgtctttg aatgtttgtt ctgtgtaacc tgcagatttc
     2341 aattgtgaat caaatgaatc acccaattgt ttctttgttt gatcatattg agaatcgatt
     2401 tctttggttg atacgtcatc tccatattta tcttcaaata cttgataaac gatcaactgt
     2461 tgcacagcgg aatctgctcc ttgcattttt ttcaagctat ccattacttc ttgttcgctg
     2521 attgtaccgc ctttataact aacggctgtt ttttcaccgg cattcgtaca gcctgacaat
     2581 aagccagtgc ctagtacgat ggcaagtgct aaaaatcttt ttttcattta tcaattctcc
     2641 tacttttcgt tttttgcgaa ttgctaaaaa caaaggtgtt caagatgaaa atcatcaaga
     2701 acacctttac taatctgctc gatacgtcct gaatagatat aaggctacac aatccagaaa
     2761 gttcgctcag cagaataaat gtcaagtagc acatcacacc ttaatatact acttcttttg
     2821 ttaccgtttt tcaagtctat cttgcgttcc gtatttaacg taactaattc ttagaacaaa
     2881 tgttatcgat tttgtttttc ttcttccgct gctgggatat tcaaatcaga cacttttatg
     2941 ttcgattttc cagacatttt tttgttgttt ttattatgat atatttttat acaactaaaa
     3001 atgaatatat taaaactacc aaaaataact tttaacgctg tttcattata tgttttttct
     3061 attttatata aacttttgga tacttaatac caaccggttg gattgtacca acatgagaat
     3121 gtgtcagttc tatttcctgt cgcacttgca taggcccata ctccttttgt tgcatttgct
     3181 gatcgaatag agtttccaac tttcgctttt gcaccgtgac gattatagac acgactatag
     3241 tggttagaat gacctgtttt tctcgtacaa gttgtatcac tataataaac ccatcttcca
     3301 gagctatgat taattgctgt tctagaaatt tcccggtcta ctggtaaatt tgacttaata
     3361 atattacctt tagcatcaaa atgaatctct cctggcttta aagatttgta atagatttca
     3421 ccgtgaactg aatttgcttc cacttcagat gacatagcgt ttcctccaac aaaacctatc
     3481 cctagtgcac aaataataac tgcttttttc ataaaacgac atcctttcct ttttgatttt
     3541 taaagcatga tcttcttgtt tcctattttg gtcagatatg gatcatgcgt gactacgata
     3601 actaacgtac cttgggaagc ttgttgcgat aagatttcaa ctactttatc cttatttctt
     3661 ttatccaatg acccagtcgg ttcatcggct aaaatgattt tgctattctt caataagact
     3721 ctcgcacagg cgattctttg cttctcacca ccagataatg tgtagatagg cgtacttagc
     3781 ttcttgttta tatttacttt tttcaatgcc tcatactttg ctgttcgctt atctgaaaca
     3841 tttaaattcg aaaacttcaa tccaatatct aaattaaaat cgattgtttc atattcaatc
     3901 aacccaaaat cttgaaaaag aaaagatatg gtatttcttt ttatcaagcg cttctctctc
     3961 ccagttaatt gtttcgtctc ttgatcgaac aaatagaatt gtcctgaact gaactgatca
     4021 ttcaatccta atatattcaa taacgtactt ttacctgctc cactttctcc aacaacagtc
     4081 acaagatccc cagcatccgc agtgaaacga tccaaatgaa gaatcgtttt gtttcgaatg
     4141 atttttttcg caccttttat cactatcaac ggctccaatt gttaacctcc attcatcagc
     4201 aataactgac ttttcttttc tgtagacaaa ataaaaacaa ctgaaagaat aaaatcaatg
     4261 aagctaaaga aaaaaatatt aaaaagatat ttaggctctc tttctataag aaaaaggaag
     4321 attacacttg tcgttcccca tttgatgagg ttcatcatga agaaatcttt atacgtttca
     4381 aagagcgaat aaccacttga acgaaagata gcgattttcc gacaattgta gacaaaatat
     4441 atgcataaca tgacatagct caacaagaag aaagaaaaga aagtgagtaa aaatatctgt
     4501 atcaagtaat gaaatgatct gcttaacact ttgacagcta tctcttcagt ctgagtatac
     4561 ggaaatgata actgcaagtt atcacgtaac tgactttctt caatcagctc aaataacctt
     4621 tctttcgaca aagagcctat cttgatcttt aacggtggat agatttctcc gctgagaata
     4681 tttctttcca aatacatact gtttttcaat gtcagtattt caacaaccgg ataatgttcg
     4741 atccagggga tagaaggaat aaatgtataa atgggttgat tgttttttat aaatagaaat
     4801 ttcggttctt tttcactgat ttcttgataa tattctgtta tttgcgccag gtcatttttt
     4861 aaatctgtat gtctatatcg ttcagggatc aatataacag ggtgcgtttc tttttcggtt
     4921 atttggatca accttccaga gacatcaatc aaaggaaatt tcttaagata attcagattt
     4981 atttttatcc ctctgccaaa ctgttcattt tcttcattca agtaatctga tacattgact
     5041 aatatacttc cgtttttatt caaagtttca tataattcct gatctgctgc tgatgcaaaa
     5101 cgattggaat aaataaaatc cacgtggttt ttcccgatgg ttactggata aaatacatga
     5161 tagtcctcac cagcgatttc ttttggtggt tcatgggaaa cagctaactg tgaagaagaa
     5221 aaaacgatag ttgctaattc gacattggca acggtcaaaa gaagagaaaa caacaatcca
     5281 aatgtaaaaa gaatgtattg gatatagttg aacgcttctc ttaacgaagc gattttttca
     5341 actaataaaa gagaaatcaa agagatacca tatattccgc tgaacaagaa aacgtacatc
     5401 tggaacaaat aaagaaattg ctccttataa tacataaaaa taaaaccacc aatgattcct
     5461 gcaattatga atgtaataat gattttcttt ttccccaata aacaccacaa tacttgatgt
     5521 aatgaaaagt cattattcaa caataaactg atttctttat tcatcaataa gaaaaaggat
     5581 gataacaaaa ggaataaaag aatcaatcca atagttaaat acactcgata attatatacg
     5641 tctgtatttg aaataaccga atacgaatag ctattttcaa agtcttcaaa aatattagtg
     5701 gcataatcag tgtgaaatgc ttgattgaat cgatcagtga atagtgaaat gaaccgttca
     5761 taggcttctt tttctctcgt catcaagaaa aattcacctt caaaatcttt tattttgatc
     5821 gattcttcaa tggacgttac gcgaaaggag gtattagaat agggtacctt ctcgtgagaa
     5881 gatttgacat ccccttgata atacaatgtc atttcaagct ttggctgtat cttgaagttc
     5941 caagatgtat ctacttcatt ggattcattt actgtttttt tcatataaga aagctcagtt
     6001 tctgatgaga cattttcaaa taccatgatt agctgctcat attcttcttg cccaataaaa
     6061 tgttgtggca atcgaatcgg agtataagta tctgtttgat ggaaaaattc atttgtccga
     6121 tagagtacct gtttatttat actaaccaag gcaaaaccac tcatgatacc ggtcactatg
     6181 attgtgagta aaactgtgaa cttttttttg attatcacca ctctccctta cttaaatgat
     6241 tctttgataa aatcataccg tttttcatca aaaaaacgta tctatcaagt gtataggtca
     6301 tgtagaataa atctatatac tgtagaatcg aaaggagaag aagatgaaca ccggagaaaa
     6361 aatacgaact taccgcagaa attgtaagct tacgcaaaaa gaattaggcg aaaaaattgg
     6421 tgtttccgat aaaacgattt ctagttggga aaattctcgt acaatgccag accttgaaat
     6481 gctgtcactt ttacatcata ctttaggtct gccgattgat tttccttcta ttgaatcagc
     6541 taccgaatca atagaaccaa cattgccaga tgaacctctt gttaacaaga aatcttattc
     6601 atcaaaacaa cccttctcac tcaaaaagac actatctttc tttctgctcg tcttttgttt
     6661 ggtctatctt tttcttatca attatcaata caaaaatgaa acgatcgatc gattcaatcc
     6721 ttttttgaaa ccacaaatcg gctataccac actccctgta ggatacgtgg acaattccat
     6781 cgaacgttgg gtatgtaatg atatctttgg ccatggtaca tggctgtctt ttcacgctgg
     6841 agaggtagaa aaagagaaaa accatgctgt aatcaaacac aaaggaaaac acgtcatgaa
     6901 cgttcgcctg ctcacttggg aagccattcc ctcagattac caagaaatcc tcagccaaga
     6961 ctatgacgac gccttaaaaa gaagccctca ggagccagat aggcattaag taggagatga
     7021 acgtagagat agaaaaaatc aatgcacatg atcttatcca aaaaacaggg gtacaaatta
     7081 attgaaaaag ccttgagatg aaagttccta aataaaaaag ttcagaatga taggtatttc
     7141 tggcttatag tataatattt acgccacagc ctcccaatga ttctttttgg aatcataatc
     7201 aaggatggac attcacaaaa atattttgct cattcgatcc gaatagatta acgaccaatc
     7261 tagtaagtaa tatagattgg tacgtagtca agctgcacat aatttagatc aattttagtt
     7321 cttttttata tttctatgat ctgctcattt acttttatat gatggcttac agtaacataa
     7381 ataaatatga taatcgctgg tagtttatcc aagagtactc aataaaatac aaaatggatt
     7441 gttcaagcgc ctatcataat gataaaatga aacaaataaa cgatacaagg aggaagagac
     7501 tttgagtaat ggcagaacaa ttttttcatt gtaaaaattg ttcagttgtt aatctatggg
     7561 atttcggtag catgggcatt tttttataga ggaatcacac caacctggcc gttttatctc
     7621 ttgttagtgg gaatattagt aggaaatttt gcccctcttc actatcgtac gaactttttt
     7681 ccaactgatt ctggcctttt tcttaaaaca aagacgcgaa aattagaaaa cattattgaa
     7741 atgacaatta cctgtataat cattttctta gttatattcc taaacgtctt ctaataagaa
     7801 tctcttaaaa ttagcttgtt acagttagtt acctagttta tataacacag ttatcttatc
     7861 ttccttatca acatcttttg ccaactcttt gtcttaaatt cgaaacatat aagcagagct
     7921 acgaacacca agactgtttc ggctctgttt tttgcatcaa attcactctt atatagctga
     7981 taatctcggc tctttaaaag aaattatttt cgcttcattt tattataaaa aggctaggaa
     8041 ccttgatgtt atcaggttcc tagcctttat ttaagtatta ccccacagac ccttccatat
     8101 agatttttaa attacacact agtttaaact aaaacaaaca aggaaacact taccatttaa
     8161 tcataaaatt agctcatatg aatatattag aatgtaaaat agactggtca aaatctggtc
     8221 aaaaaagagg actaatacag gtagtcctca gactgtagac aaagtccatt ttatggatga
     8281 tatctacagt cttttctttt ataatagatt tatgaaaacg aatgcaagga gtgatagcta
     8341 tgatgtctaa aaacaatacg aatggtagaa atcaatttgc gatgcttacg attgatgatc
     8401 tagttcctca agatcatctc gttcgaaaga ttgatgccgc gcttgatttt gaatttattt
     8461 atccaatcgt cgaagccact tactccgatt taggtcgccc aagtatcgat ccagtgattc
     8521 tgatcaaatt ggtgtttatt cagtatttat tcggtatccg ttccatgcga caaaccatta
     8581 aggaagtcga taccaatgtc gcttaccgct ggtt
//
LOCUS       DASHXG010000086         8490 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.090, whole genome shotgun sequence.
ACCESSION   DASHXG010000086 DASHXG010000000
VERSION     DASHXG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.090"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..173)
                     /locus_tag="U2R59_002564"
     CDS             complement(<1..173)
                     /locus_tag="U2R59_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8966899.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="U2R59_002565"
     CDS             complement(593..1714)
                     /locus_tag="U2R59_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HEM8966900.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="U2R59_002566"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="U2R59_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HEM8966901.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="U2R59_002567"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="U2R59_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HEM8966902.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="U2R59_002568"
     CDS             complement(4304..5215)
                     /locus_tag="U2R59_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8966903.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="U2R59_002569"
     CDS             complement(5232..6239)
                     /locus_tag="U2R59_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HEM8966904.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="U2R59_002570"
     CDS             complement(6236..8365)
                     /locus_tag="U2R59_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HEM8966905.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8490)
                     /locus_tag="U2R59_002571"
     CDS             complement(8370..>8490)
                     /locus_tag="U2R59_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8966906.1"
                     /translation="GQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2677 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg
//
LOCUS       DASHXG010000087         8067 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.091, whole genome shotgun sequence.
ACCESSION   DASHXG010000087 DASHXG010000000
VERSION     DASHXG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.091"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..883
                     /locus_tag="U2R59_002572"
     CDS             <1..883
                     /locus_tag="U2R59_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HEM8966907.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            931..3060
                     /locus_tag="U2R59_002573"
     CDS             931..3060
                     /locus_tag="U2R59_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HEM8966908.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3035..3724
                     /locus_tag="U2R59_002574"
     CDS             3035..3724
                     /locus_tag="U2R59_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966909.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4132..4818)
                     /locus_tag="U2R59_002575"
     CDS             complement(4132..4818)
                     /locus_tag="U2R59_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966910.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4954..5148)
                     /locus_tag="U2R59_002576"
     CDS             complement(4954..5148)
                     /locus_tag="U2R59_002576"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966911.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="U2R59_002577"
     CDS             complement(5198..5638)
                     /locus_tag="U2R59_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HEM8966912.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="U2R59_002578"
     CDS             complement(5642..6487)
                     /locus_tag="U2R59_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEM8966913.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="U2R59_002579"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="U2R59_002579"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEM8966914.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2481 a         1515 c         1713 g         2358 t
ORIGIN      
        1 tatttcagta ccggttgcac tgttctcatt tatgggctcg attatggctg gaatctttgc
       61 taatatcgtc aatttcaaac aatatcaaac gatttatgct ggtttcaatc cagcggctga
      121 aagctatact tataatgact atttccaaat tggtatgatt gggatgattg taagcttagt
      181 tgtggtacta acggtcgcta atatatcaat gaacaaaaag aaacgctatg caatggcagc
      241 aaacgtacca gctgaaggtg gcgacgcacc aatgatctca tggttagccg tattattacc
      301 agttttaggg gtcgttcttt tagatcttca aatcatctta ggttttattc tagcaggtat
      361 ctgggcattg ctgtttactg gaaaattgcg cggaggttat aaagaaatct gtcgtcagtt
      421 tgcgaaatta tttacagatg gcgcagtcga tgttgcacca atggttggtt tcttgatgac
      481 cttagcgatg ttcaataatt cagctgcgta tgcttctcct tatttttcag ctatttttgg
      541 agattggata ccgcaatcac cattagtctt ggcaatcgta tttgctatat tgacaccact
      601 aggatttttc cgcggtccaa tgaatctagt cggttcaggc tcagctattt tagctgtcgt
      661 gttagctgtt aatccaacga tgtcgccagc ctttttgttc ccgttatttg caattacaac
      721 gattgctcct cagcatttag atattacaca atcttgggtt gcttggggat taggttatac
      781 aaaagtaact tctcgagaat atatgaagaa atccatccca actggttgga tcatcggtgc
      841 gatcttatgc ctgatcacgt tcttattgta cgggaacgcc tagtaaacaa aacgtcgata
      901 aaaacgatta gataaatgga ggaaaagaaa atgaaacgtt ttgtgcgaat gggaattgat
      961 gttggcggta cacatacgaa agcagtcgca atcgataatg cgacgcacga aatcatcgga
     1021 aaatcttcag tgaaaacaac ccacgatgat gtccgtggag tagctgcagg tgtcgttcag
     1081 tcttttcaaa attgtttgcg ggaaaataat atcagtccag aagatgttgt gtttgttgca
     1141 cattctacca cacaagcgac taatgcactg attgaaggag acgtagcaaa agtcggcgta
     1201 atcgggatgg caaaaggtgg attagaaggt tttttagcaa aacgacaaac tagattgaac
     1261 gatatcgatt tagggaataa gaaaaaaata gagattgtca atgcattctt acctgtcaaa
     1321 aacttaaatg tagaccgtgt ttcagaaacg atttcttctt tagaaagaga aagagcggag
     1381 gtcttggttt cttctatggc atttggagta gataatgggg aaccagaacg agttgtttat
     1441 gaagcagcat ctgtgaaagc gatccctaca acgatggctt ctgacatcac aaaattatat
     1501 ggattgacaa gaagaactcg gacagcagca atcaacgcat ctattttacc aaaaatgcta
     1561 gatacggcaa cctcgacaga agactccgta cgagaagcag gggtcaatgt ttctttgatg
     1621 attatgcgcg gagacggcgg agtaatggaa atcaatgaaa tgaaaaaacg acctgtttta
     1681 accatgcttt ccggtcctgc tgcatcagtc atgggctctt tgatgtactt gagagcgtct
     1741 aatggtgttt attttgaagt aggcggaaca acaaccaata tcggggtcat taaaaatgga
     1801 cgtccagcaa tcgattattc aattgtaggt ggccacccaa catatatctc ttcattagat
     1861 gttcgggttc taggtgtggc aggcggttcg atggtacggg ctaatcagtc aggaatcatc
     1921 gatgtcggtc cacgttctgc acatattgcc ggtctagatt atgcagtatt tacggagaca
     1981 gaaaaaatca aaggtcctaa ggttgaattt ttctctccta aagaaggaga ccctgctgat
     2041 tacgtcaagg tagtgatgga agacggagaa gaagtgacta ttacaaatac atgtgcagcc
     2101 aatgttcttg gattagtgca agaagaacat ttttcttatg gaaatgtccc atctgcacga
     2161 aaagccatac aggcattagc agactattgt catacgacgg ttgaagacat cgcagagcag
     2221 atcatggaaa aatcctatgc taagattgaa ccggtgattt tagaattggc agacaagtat
     2281 cacttggaga aagatcagat ttctcttgta ggtgtagggg gcggcgctgc ctcattgatt
     2341 acttacttta gtaataaaat gggtgtgaaa tattcgattc ctgaaaacgc cgaagtgatt
     2401 tcttctattg gtgtagcact tgcaatggtc cgagatgttg tagaacgtat catcccttcg
     2461 ccaagtaaag aagatatacg atcgttgaaa aatgaagcga tgaataaagc gattgaatca
     2521 ggcgctacac cagaatcgat cgaagtccac gtagaaatcg atccacatac ttcaaaagta
     2581 acggctatcg ctactggttc tacggaagtg aaagcaaccg atctaaccaa ggagatcaca
     2641 acagaagaag cactagagct tgctgcagag gatatgcgat taaataaaaa tgaagtttgc
     2701 ttattggaaa atacaccttt cttttatgta tgcggcgaac agaatcgttc aaaaaatgct
     2761 ggaagtcttc ggatcatcga tcaaaaagga tttatcaagg tccaacgtgg acatgcttca
     2821 tgtatgaaaa caactgcagc caattatatg acagctgtcg aacaactttg ggaagatatg
     2881 gcagtttatc aaactgaatt gattgcccga ccagaatttt atctctgctt aggagcaaga
     2941 gtctctgatt ttacagcgac ggatctggaa caactacagc ttttgatgga tctggaagta
     3001 tctactatgg aaccggagga agaagtgatc gtcgttgccg gaaatatcaa acaaacataa
     3061 gttagaagag ttactaaacg aattacaaca gatccccgaa gaaatttggg gattctacca
     3121 gtttcggcga gatttatttt ggaaaaagat tcctttgtcc aagcagaaaa ttcttataca
     3181 acaatcaatc gattgtggta tcgaaacggc atgtagcatc aaaaaaaagt acccttttgc
     3241 cgatgtagga gaaatctgtg aacaaatggc tgttccaatc gtttcctgtg aatcagagca
     3301 aataaacgaa cgaatcactt ttgcaactta tgcagaagat gaagggatcc gattgatgac
     3361 ggagccgtta gaaaaattaa aatgttcagg actagcttcg atctctaaag aaacagcgca
     3421 agctttgatt attggacatg aactatttca ccacatcgaa gcttctgtta agggaattta
     3481 tacgcaaagc gaaaaaattg tgctgtggcg gttgcctttt tatacacatc aatcaaacat
     3541 tcgtgcattg agcgagatag cagcgatgag tttttcaaaa gagatgaatc aaagcgattt
     3601 ttcgccttat gtattagagg cagtcttact ttggccatat aatgaaattc gtagccaagg
     3661 gatcttagaa gaaataaaag aaatagaaaa aagatgtacg gagtatgatt tagattacaa
     3721 ataaagagac tgtgacaaaa gtcgtgtcac agtccttttt ttccgaataa acggtgttct
     3781 cctgtcaact cctcggtcac aagtcaaaat attcaacaaa catgagaagc tgttttttga
     3841 aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttgga aaaaggtgtt
     3901 caaaagcttg catctgcggt aataagaaca gccaagttaa aaacataaga agctattttt
     3961 acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctc aataaacggt
     4021 gtgcaatcag ctgaccctcg gtattagctc aaaaaaaacg gcaaaatatg aggaactatt
     4081 ttgccgttta tttctctaat actcaggtca aaacgctgat tccaaaacct cttatttgat
     4141 gggtctgtcc tgaatatctt caaaataatc ggggtaatta tgaatcacgt attcttgctc
     4201 ctcgataatc atatgtaaat gcatcgtgca aagaaatccg acttcatcaa agttatgatc
     4261 aatcattgat tgaagcattg tctgatgttc atctaatact cgaccccagt ctaattctga
     4321 aatcgtcaaa cgtaaccatc tgaaacggtt caagtgcgta ctataacttt ctagccaatc
     4381 ccaaatttct cgttttccag caatttcata acaagttcgg tgaaaatcag tatccaaatc
     4441 aaaaaaagct tttttatttt gagcgatcac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccgggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgttctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt tcccgtatac ttttggatag
     5401 ttgggtggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccacttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aacagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcctgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcaacaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaatctaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccact gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaatcttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcga aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ttcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataaaaatac taaaaaa
//
LOCUS       DASHXG010000088         7785 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.095, whole genome shotgun sequence.
ACCESSION   DASHXG010000088 DASHXG010000000
VERSION     DASHXG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.095"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(192..1484)
                     /locus_tag="U2R59_002580"
     CDS             complement(192..1484)
                     /locus_tag="U2R59_002580"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEM8966915.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            complement(2264..3631)
                     /gene="dnaB"
                     /locus_tag="U2R59_002581"
     CDS             complement(2264..3631)
                     /gene="dnaB"
                     /locus_tag="U2R59_002581"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEM8966916.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            complement(3905..4357)
                     /gene="rplI"
                     /locus_tag="U2R59_002582"
     CDS             complement(3905..4357)
                     /gene="rplI"
                     /locus_tag="U2R59_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEM8966917.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            complement(4363..6336)
                     /locus_tag="U2R59_002583"
     CDS             complement(4363..6336)
                     /locus_tag="U2R59_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEM8966918.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            complement(6479..6715)
                     /locus_tag="U2R59_002584"
     CDS             complement(6479..6715)
                     /locus_tag="U2R59_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEM8966919.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            complement(6741..7253)
                     /gene="ssb"
                     /locus_tag="U2R59_002585"
     CDS             complement(6741..7253)
                     /gene="ssb"
                     /locus_tag="U2R59_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEM8966920.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            complement(7303..7602)
                     /locus_tag="U2R59_002586"
     CDS             complement(7303..7602)
                     /locus_tag="U2R59_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEM8966921.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
BASE COUNT         2151 a         1650 c         1400 g         2584 t
ORIGIN      
        1 ttcggaaaaa gggactgtga cacggttttt gtcacagtcc cttattctga ataaacagtg
       61 ttcaagagac agcctatcgg caataaggct aaacgtctct ttcactacct cttcaagtta
      121 ttattatcgt atagataaac acttcgactc gctctggtaa gaacgtcctg attcagtcgt
      181 cgtttttatc cttagatttg cgcccagacg ctttctaaga tgtttgtttg tgttctatca
      241 ggtccgacag aaaatgttga gatacgtaca ccaacaagct ctgagatacg acgtacatag
      301 ttacgtgcgt tttctggcag ttctgcaagt gttttgcatc ctgtaatgtc ttctgaccag
      361 cctggcaatt cttcatagat tggtttgcag cggttcaact ctttcaagct tgctggatag
      421 tggtagatta gttcgccatc taattcataa gccgtacaaa tttttactgt ttccaatcca
      481 cttaatacat cgatcgagtt taaagatagg ttggtaatac ctgaaactcg tttagaatgg
      541 cgcataacta cagaatcaaa ccagcctaca cgacgcggac gaccagttgt cgtaccgtat
      601 tctcgtccta cttcgcggat ttgttctcct gtttcatcaa ataattcagt tggaaatggt
      661 ccatcaccga cacgtgacgt ataggctttg cagacgccga caactttatt gatttttgaa
      721 ggccctacac cgcttccgat tgttacccca ccggctactg ggttagaaga agtaacaaaa
      781 ggataagttc cctggtcgat atccagcatt acaccttgtg cgccttcaaa caacacgcgt
      841 ttgcctgcat ccaaagcatc attcaagata acggaagtat ctgtgacgta ttgtttgatt
      901 tgttgtccgt attcataata ttcttcaaaa atatcgtcaa aatcaagtgg ttctgaatca
      961 aacattttta caaattgacg gtttttgtca tctagattca aacgaagacg ttcttcaaaa
     1021 atttctttat ctaataagtc tgcaatacgg atacctacac gagctgcttt atccatatag
     1081 gcaggtccga ttcctttaat cgttgtacca atcttatttt cgcccttagc atcttcttgt
     1141 aattggtcca atttgatatg ataaggcaag attacgtgcg cgcggtcaga aatacgcaaa
     1201 ttacttgttt ctacaccttt ttcatgtaaa taagctaatt ctttaaccaa tgatttagga
     1261 ttgactacaa cgccgtttcc gatcacactg atcttgtctt tataaaaaat cccagaagga
     1321 atcaaatgca gtttataagt cacaccgtta aacttaattg tgtgccctgc attgtcgcca
     1381 ccttggtacc gtgcaatcac ttcagcattt tcactgagaa agtctgtgat ttttcctttc
     1441 ccttcatcgc cccattgcgt acctactact actacagatg acatgtgaac acctcgttct
     1501 atattattta atcctgaacc attgtatcaa taatagatac atatttcaaa taaaatcgaa
     1561 tgatttttat ttttatttta taaaaacgct taaaaaacga actttatctt tttagaatgg
     1621 ttattaaaaa agaggttgta acagaagtgg tcagcttcaa gaaataagaa ggaatgtacg
     1681 aaaattgctt ctcaaatttt tgtgaaattt cgacttattt ttcgaagaag ctacttttgg
     1741 aacaccgtga atcagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa
     1801 acaaaaatag cttctcatat ttttcgtttg attgggcgta ttaccgcaga tgcaagcttt
     1861 tgaacaccgt ttaagaaaga ggttgtgagc ctgccgttta actctgagtc acaaggagca
     1921 atttcaaaaa actgcttctc atgtttgatg atattgtgac ttgtgaccga ggagttggca
     1981 ggagaacacc gtttaaggaa aagaggtcgt aagatcagcg ttttgacctg agtattagag
     2041 aaacaaacgt caaaatagtt cctcatattt tgacgtttgc tgagctaata ccaagggtca
     2101 gctgattgaa caccgtttat tcggaaaaag ggactgtgac aagacttttg tcacaatccc
     2161 tttggagatc tgtttaaatt aagtactcta gtcgttcctg cggttactcc ttgcatcttc
     2221 ttacgagagc tctcgggatt gctcaaggct cacaacctct tctttaaaat tcttctcttg
     2281 gcgaaagcga cgaaaactta ttgtattctt tgataaacag tagttcaact gttcctcgtg
     2341 caccgcttcg gttcttctcg atgatgactt cgatgacgtt gtcatttttt ggctcgtttc
     2401 catcatcgtc atctccgcct tctctttcat aataatcatc tcgatacaag aaggctacga
     2461 tgtccgcatc ttgttcaatt gatccggatt cacgaatatc acttagcact ggtcgtttgt
     2521 cttgtcgctg ttctactcca cgagataact gtgaaagagc aatgacaggt actttcagct
     2581 ctttcgccag ttttttcagt tggcgagaga tatctgatac ttcttgttga cggttctctt
     2641 taccgttacc ttcaatcaac tgcaaataat cgatcaatat caagcctaga ttgccttttt
     2701 cttgcgctag tttccgacat ttcgcacgga tttcagagat tttgatccct ggtgtatcat
     2761 cgataaaaat atttgctcga gaaagactcc ccatcgcaac gatcagattc gaccattctt
     2821 cttccgaaag ctgacctgta cgtaaatggc tggcctcaat cgaaccttct gcacaaagca
     2881 tccgatttac aagagattct gcccccattt ccaaactaaa tatcgcaaca gaacgatctg
     2941 tttttgttcc tacattttga gcaatattca atgcaaacgc tgttttacct accgctggac
     3001 gtgcagcaag aatgattagt tcttcgggct ggaaacctgc tgtcatttta tccagacctt
     3061 gatagccagt tggtagacct gtgatttctt cattgttttg agctagtcga tcgatatttt
     3121 caatcgtgga gttcagtact tcagcaatag ataaaaagcc gcttcgattt cttttttccg
     3181 aaacctccaa gatactgcgt tcggcatcat ctaaaattgt ttgaacttct tctccttgct
     3241 cgaatccttt cgtaacgatt cctgttgctg tctggatcaa tgtacgcagc aatgattttt
     3301 cttcaacgat tttcgcatag tagacgatat ttgctgctgt cggaactgct aatgccaagt
     3361 ctgagagata acttaaacca ccggcatctt ctaacaaatt ggcttgttcc agccggtctt
     3421 tgacagtaac cacgtcaatc gcttcattac gatcatttaa ctcgatcatt gtctcaaaaa
     3481 taatttgatg gccacgacga taaaagtctt ttggctctat gtactccatg gcatcaatga
     3541 tcgtttctgc gtcaagaaaa acagagccta aaaccgcttg ttcagcttca atattttgcg
     3601 gtgggattcg atcctgccac acttcattca tacgtatcgc tccttgtctt caattgcttc
     3661 attttacaag aaaatgagag aaaagtcatc attcgtaccg aaagtgtaat aaaaaaatag
     3721 ttctctttta ttatactcgt tttctttatg ctattttgct gttcccaaaa aagaaaccga
     3781 aatcaatctg aaatcgattt gcagcttttg ctttcattgc tgcagctgtt ttctcagata
     3841 aatttcggtt tgtctttttt ccttctggtt atacttacca gctgaacatc gctatcaaga
     3901 tttgttattc ttgtacgaca tgaactttga tcgtagccgt cacctcatga tgaagcttaa
     3961 caggtacgtt tgtgtagcct agtgaacgga tcggattttc taattcgatt tttcgtttat
     4021 ctaatttgat tttgtattgt ttgtttaacc cttcagcaat ttgttttgaa gggatcgaac
     4081 caaacaaacg gctgtcttcc cctgctttcg ccttcaattc gactacagta tcttcttttt
     4141 ccaagaattc ttttaacttt ttagcttctt ccaagatttc agcttcgtgt ttttcttgtg
     4201 ctttcttttg tcctgctaac tgactgatac tgcttttcgt tgcttctttt gccaagttat
     4261 ttttgattag ataattttgt gcataacctg ctggaacttc tttgatgtcc ccttttttac
     4321 cttttccttt tacatcttgt aaaaaaatta ctttcatttg gattactcct tatcatatat
     4381 ttgattcata ttttctttga ttgcagcaaa tagcttctgt tttgtttcct caactgtcgt
     4441 attttccagt tgagtagctg cgtttgtgaa gtgtcctccg ccacctaagg attccatgat
     4501 gatttggacg ttgatcgtgc cggtacttct ggcactgatc ccaatcaagc cgtctgtccg
     4561 ctttgtaatg acgaaagctg cattgatatt gatcatcgaa agcaatgtat ctgctgtttt
     4621 tgctgctata acactattat actctttttc gtctgtccct gccgccacaa caatatcaga
     4681 agtcacatag tcgcttccag caatcaaatt gctgatctcc aagtatgtcg ctaaatccga
     4741 gctcaataaa tattgtacta aggatgcgtc tgctccacaa gaccttaaat agctggcaac
     4801 gtcaaaagtt cgtgcagttg tacggacatt gaaactattt gtatctacaa ccatccctgc
     4861 aagcaataat gtggcctcaa aacgatctaa gcgatttgtt ttgctgcttt ggtattggat
     4921 cagctcagaa actagctctg aagctgaaga agctgaagat tcgatataag tcagcagagg
     4981 tttacttgga aactcttccc cacgacgatg gtgatcaatg atcacaatct tatcaaattg
     5041 ctcatatagg ccctgagaga tcgatagaga aggtttatgg taatccacca tcacgaggag
     5101 gtcctcttct tttttcagct ctatggcacg ttctggagag attagttgca tttctaattc
     5161 aggatgctta tggatttctt caagacaccg ttctacatct ggaatgatct cgttctcgtt
     5221 gataacgatg taagcttttt tctggttgaa gcgtgccaga caactgacac caaaagcaga
     5281 gcctaaagca tccatatccg gaaacttgtg ccccatgata aacacatcgc ctgtttcatc
     5341 aaaaatccga cgcaaagcgg tactcatcgc tcgagaacga acacgcgtgc gtttgacatt
     5401 cttagcagat ttccccccat aataaacagg ttttgctcct tcttttacct ctttcacgac
     5461 aacttggtcg cctccacgga ctaaagcaac atctaaatta ttctgagctt ctccaccgat
     5521 ttcatcgagg gttcttgagc cataagcaat ccccatacta agggtgatag gcgagctctg
     5581 tttttcagct tctgctcgaa agcgatccag caaatcaaat tttttatcca tcatcttttt
     5641 cagatcgatc atctgtgcta cgaagaaaaa ccgttctgcg ttgattcttt tgaaaaagac
     5701 atggtattca ttcatccagt cagaaactag tgtagtgacg aaagagttca aataagaaat
     5761 ctctttgtca tccaatttat caatggcatc tgcatagtta tcaatagata aaataccaat
     5821 caccggctga ctgttcgtct gatggagttt taacaactgg ttttgggtaa tatcattaaa
     5881 ataaacaaca ccctttactg tatccatatc aaactgaaat gttttatctg ctagatagac
     5941 ttggtttttc tttttttctt ttgcagtaaa aaaagtatct agcaattctt cctctgttaa
     6001 tccactttga tctttgattt tcaatgctaa tggattgagc cattcgattt tttggcttga
     6061 tggctgataa gcaatcactc ctacaggcat gacttctgag acataagcta gattggtttc
     6121 agctacagtc gaagcctgct ggattttttc acgtttattt aaaataagcc aacgtttcat
     6181 tttcaaccaa tagcgaacac cccataaatt catcaataga atgaccgaag cgctaacaaa
     6241 acgaaatggt aaaattaaga ctaccaatac ttcgattaat ataaacagga taaggaagag
     6301 aggtttcggg gataaatgat tgtttttatt ttccataatt ttcctcccat atatgactaa
     6361 tttgatttta ccataacttt cgtcattcga gcgactaaac gaatagaggt tatttttaca
     6421 gaaaaaaagg aattgaatag ctgatcaaaa ggatcagtca ttcaattcct aggatttatt
     6481 agtcttcgct aacgaaaggt agcaagccca tgatacgagc gcgtttgatt gcaacagtaa
     6541 ttttacgttg gtttttagcg cctgtaccag ttacacgacg tggcaagatt ttaccgcgtt
     6601 ctgaaataaa tctttttagt aattcgatat ctttataatc gatatattca atatggttag
     6661 cagcaatgta gtctacttta cgacgtttac gtccgcctct tctttgttgt gccattctat
     6721 ttccctccta tcaaattcgt ttagaatggt aaatcatcgt ctgaaatgtc gatcgttgaa
     6781 cttgagccga atgggtcaga agtatcacgg tcgaaatcag gcataccgtt ggatgattga
     6841 gatgtttgat tagagttatt gtttccgcca aatccgccag ctgattgacc agaactttgg
     6901 aatccgccgc tttgttggcg attttcagat gcagaacgac tttccagcaa ttggaagttg
     6961 tcagctacta cttctgtcac gtatacacgt tgtccttgct gattatcata agaacgagtt
     7021 tggatacgtc cagtaacacc taaaagtgtt cctttacgag catagtttgc taaagtttct
     7081 gctgatttgc gccaaatcac acagttgata aaatcagcct cgcgattgcc gctttggttt
     7141 gtaaaattac gattcacagc caaagtaaat gttgcgactg ccgtaccact tgctgtgtaa
     7201 cgcaaatctg gatctttcgt cagacgtcca actaatacaa cattattaat caaaatagtc
     7261 atctcctctc atcgttttct attgtttcac atgaaacaac aattaagctt cttctttaac
     7321 aatcatgtga cgaatgatat cgtcgttgat tttagcaaga cggtcaaatt cattgacagc
     7381 atttgctgat gatggagaag atactttaac gatgtgatag ataccttcac ggtaaccgtt
     7441 catttcataa gcgaaacggc gtttttccca atcttttgat tcgataactt ctgctccgtt
     7501 atctttcaag attgcatcga aacgttcgat taaagcagtt tttgcttctt catcaatgtt
     7561 tggacgaata atgtacatga tttcatattt cgtgttttcc attgatattc acctccctgt
     7621 ggactttcgg ctcttaggtt cctaagagca aggagagtta tctaattaat tagactactc
     7681 acaagctctg attatacact ctattttggt caaaagcaat acagaatgaa cagtttcgaa
     7741 tattttaaga gaaattcaac taatcaaaaa agccagcagg aataa
//
LOCUS       DASHXG010000089         7598 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.096, whole genome shotgun sequence.
ACCESSION   DASHXG010000089 DASHXG010000000
VERSION     DASHXG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.096"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(941..1354)
                     /locus_tag="U2R59_002587"
     CDS             complement(941..1354)
                     /locus_tag="U2R59_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HEM8966922.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="U2R59_002588"
     CDS             complement(1810..2295)
                     /locus_tag="U2R59_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966923.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="U2R59_002589"
     CDS             complement(2434..2649)
                     /locus_tag="U2R59_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HEM8966924.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="U2R59_002590"
     CDS             2873..3673
                     /locus_tag="U2R59_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8966925.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="U2R59_002591"
     CDS             3692..5560
                     /locus_tag="U2R59_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8966926.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELCDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="U2R59_002592"
     CDS             5553..6044
                     /locus_tag="U2R59_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HEM8966927.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /gene="srlA"
                     /locus_tag="U2R59_002593"
     CDS             6032..6586
                     /gene="srlA"
                     /locus_tag="U2R59_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEM8966928.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="U2R59_002594"
     CDS             6604..>7598
                     /locus_tag="U2R59_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEM8966929.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1213 c         1444 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatgcgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DASHXG010000090         7537 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.097, whole genome shotgun sequence.
ACCESSION   DASHXG010000090 DASHXG010000000
VERSION     DASHXG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.097"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            107..1248
                     /locus_tag="U2R59_002595"
     CDS             join(107..335,335..1248)
                     /locus_tag="U2R59_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8966930.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="U2R59_002596"
     CDS             1483..1935
                     /locus_tag="U2R59_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966931.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="U2R59_002597"
     CDS             1949..2638
                     /locus_tag="U2R59_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966932.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="U2R59_002598"
     CDS             2763..5114
                     /locus_tag="U2R59_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HEM8966933.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="U2R59_002599"
     CDS             5194..5589
                     /locus_tag="U2R59_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966934.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="U2R59_002600"
     CDS             5914..6531
                     /locus_tag="U2R59_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966935.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="U2R59_002601"
     CDS             6572..6871
                     /locus_tag="U2R59_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HEM8966936.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="U2R59_002602"
     CDS             6905..7072
                     /locus_tag="U2R59_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEM8966937.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="U2R59_002603"
     CDS             complement(7117..>7537)
                     /locus_tag="U2R59_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8966938.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DASHXG010000091         7390 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.098, whole genome shotgun sequence.
ACCESSION   DASHXG010000091 DASHXG010000000
VERSION     DASHXG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.098"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="U2R59_002604"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="U2R59_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEM8966939.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="U2R59_002605"
     CDS             complement(1804..2697)
                     /locus_tag="U2R59_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8966940.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="U2R59_002606"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="U2R59_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEM8966941.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="U2R59_002607"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="U2R59_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEM8966942.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="U2R59_002608"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="U2R59_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEM8966943.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1975 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc
//
LOCUS       DASHXG010000092         7147 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.099, whole genome shotgun sequence.
ACCESSION   DASHXG010000092 DASHXG010000000
VERSION     DASHXG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.099"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..227
                     /locus_tag="U2R59_002609"
     CDS             <1..227
                     /locus_tag="U2R59_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEM8966944.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="U2R59_002610"
     CDS             227..574
                     /locus_tag="U2R59_002610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966945.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="U2R59_002611"
     CDS             571..1620
                     /locus_tag="U2R59_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8966946.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="U2R59_002612"
     CDS             1635..1841
                     /locus_tag="U2R59_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966947.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="U2R59_002613"
     CDS             1862..2458
                     /locus_tag="U2R59_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HEM8966948.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="U2R59_002614"
     CDS             3410..4009
                     /locus_tag="U2R59_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8966949.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="U2R59_002615"
     CDS             4058..4774
                     /locus_tag="U2R59_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEM8966950.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="U2R59_002616"
     CDS             4788..5567
                     /locus_tag="U2R59_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HEM8966951.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="U2R59_002617"
     CDS             5650..6006
                     /locus_tag="U2R59_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8966952.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="U2R59_002618"
     CDS             5996..6262
                     /locus_tag="U2R59_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8966953.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="U2R59_002619"
     CDS             6421..6699
                     /locus_tag="U2R59_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966954.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>7147)
                     /locus_tag="U2R59_002620"
     CDS             complement(6696..>7147)
                     /locus_tag="U2R59_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8966955.1"
                     /translation="TYIKIKGHWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLH
                     KQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKYLNNLIEQDHRSIKRRHKL
                     YQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFSVCTEIRILLGIPA"
BASE COUNT         2602 a         1014 c         1386 g         2145 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatga tcttgttcta ttaaattgtt aagatacttc
     6901 acagttcggt gctctgtctt agtatataaa cccacactct gtaactttct aaaggcggag
     6961 ccaagagaag gtgctttatc ggtcacaatt gctttcggct caccaaactg tttatggagt
     7021 cgttttaaga aagcataggc tgcttgcgta tcccgtttct ttcgtaacca gatatctaag
     7081 gttaagccgt ccgcatcaat tgcacgataa agataatgcc aatgtccctt aattttgata
     7141 taggttt
//
LOCUS       DASHXG010000093         6410 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.100, whole genome shotgun sequence.
ACCESSION   DASHXG010000093 DASHXG010000000
VERSION     DASHXG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.100"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            76..1380
                     /locus_tag="U2R59_002621"
     CDS             76..1380
                     /locus_tag="U2R59_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEM8966956.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1472..1837)
                     /locus_tag="U2R59_002622"
     CDS             complement(1472..1837)
                     /locus_tag="U2R59_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEM8966957.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1834..2199)
                     /locus_tag="U2R59_002623"
     CDS             complement(1834..2199)
                     /locus_tag="U2R59_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HEM8966958.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2391..2639)
                     /locus_tag="U2R59_002624"
     CDS             complement(2391..2639)
                     /locus_tag="U2R59_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966959.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2638..2766
                     /locus_tag="U2R59_002625"
     CDS             2638..2766
                     /locus_tag="U2R59_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HEM8966960.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2823..4517
                     /locus_tag="U2R59_002626"
     CDS             2823..4517
                     /locus_tag="U2R59_002626"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEM8966961.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4521..4640
                     /locus_tag="U2R59_002627"
                     /pseudo
     CDS             4521..4640
                     /locus_tag="U2R59_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4617..4790
                     /locus_tag="U2R59_002628"
     CDS             4617..4790
                     /locus_tag="U2R59_002628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966962.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5168..6301
                     /locus_tag="U2R59_002629"
     CDS             5168..6301
                     /locus_tag="U2R59_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEM8966963.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
BASE COUNT         2121 a         1222 c         1168 g         1899 t
ORIGIN      
        1 tgtgggcaat tctatgtaaa taaagaagtc aatctagaaa agctctccaa tctcctgcat
       61 gtttgcaaaa ccactttgct caatgatatc aataacataa aaaaagaatt tgaagaacag
      121 atcgcttata cacatcggga aaaggaccgt tacactttat atttttcaga acatatacct
      181 cgatgcaaga tcatgcagca attgtctcaa aattcgttgt ttttaaaaac ttgtctgctt
      241 tatttggaag aagatgaacc tgattatctt caattaactg aatgtgaatt catctctgtc
      301 agcaaagctt attcattaaa aaaacaagta ttagcttatt ttaatgactg cgggatcgaa
      361 atcgaccgct actcccctcg attcactgaa atggaaagac gtctgctgct tcttaatgtg
      421 tcgtatcgtt taggcggttt taattcttgg gagctacctg aatcgttttt tgaacgtgcc
      481 gatcgtttca ttgaatccgt aacggaaaat agtggcagat tttatgataa agaaaataaa
      541 gaaatcttat tgattggttt tgctatcagt ttcctacgcc agcaagtgtg tgctgtgaca
      601 atagattcaa aatttatcga agaaatcaaa aaacgtccta tttacaatta tgtcgaatca
      661 gcatgggaaa acactgattt ccaaacctat tataaaaaag aagaattcgc ctttattttg
      721 acactattca atctttgtaa ttatggtttc cattcttatc agttgattgc ggaagacttt
      781 caacagctac accaagtgtt tattgacaat actcccgaaa taaaagaact agttgctacc
      841 tttgaatctc acttcaatca agaattattc ggaaaccaac cattcgaacg tgcgctgatt
      901 catctgatgc gttcggcttg ggataactat caattattca tgccagaaaa attttatctt
      961 ctaaatgagg aacagacaaa tttatataaa gaagtccaga caattttttc cagctggtcc
     1021 agccagttac cttatgatct acggttgaat cctaattgca tgcgggcttt tgtgatcgaa
     1081 ttgagcggaa ttctccgtct gacaaaagaa catctgacta tctatatcgt cacaaattcg
     1141 gatgttcatt atctgattta tcgggaagcc ttggaagctg taactacttt cgattttcaa
     1201 gttgcaccaa caatttattc aagtatatct gatataaaga agtatgcgca gcagtcctca
     1261 aaccgggtat tatgtgaacg tacattatat acaccagatg cggtccaata tgaaaatatt
     1321 attcctattt cgatcaatac gatcgatcga gctatcattt cagctgtgca aaacaaataa
     1381 gggactgtga caaaaatcat gtcacagcct cttatttgtt gaagatgccc atttctgtaa
     1441 caatctcttg atacacatca ggctcacaac ctcacttatt ttggacatct acgggtccga
     1501 tctctttatt taaaaaataa gaaatgatgg ttcggataac taccaacgcc gctagttgga
     1561 aaatatcctg caaggtaggt ttgataatcg attcgatgat cccagctgaa acaagaattt
     1621 ccaaacttag aagtatatag cctcccaaca tctttttaat agcattgttc tcgctgactc
     1681 ggtcgctttg cacttttgta tggacaaata aatatttcaa aaaatccttg attgatagac
     1741 aaacacccca aaccaataaa cagatagcaa agatatcaag tcccagtaca agtttttcaa
     1801 aatatggaag aagaaactgc atcaactctg tcgtcatcct acctctcctc ttctttgttt
     1861 ttctttgtct tctatttcct gattcaagaa ataagaaatg actgttcgaa tgataataat
     1921 aagtgcaagc ttcaaaatat ctgtccaagt cggcttgata actgactcga tgatatcagc
     1981 aacgactagt acttccaagc ttaacaaaat ataacttgct agcagttttc ttgtatctgc
     2041 attacgagta ttacgttctg catagttttt cttgacatga gaccaatcaa aaagtttgaa
     2101 tagaacaaga acgatcccga caattaagat accgatagaa caaatattta aaatagcaat
     2161 gatccattct agaaattcaa ttaaatttga gcgaaacata tacgctacct actttctttt
     2221 aatttgttcc tattctttta ttgtaaaaga aagttacctt gttcgtctat ttaaaagttg
     2281 ttctaatgat aacggttcgc ttaaattttt ctttttcact ctcccctttt tctccctcca
     2341 tccataaatc gtggaagtat ccaaaacaac gtagcaagtt aaaataaggc ttagtccgtc
     2401 atcagctttt caaagaagca ctgtctcggt gctttttttg tacccaaatt tctaaaaata
     2461 gaaccataca cctcctcaaa tcttttcttc ttacctaccc tatttttatt tacaggaaaa
     2521 tcagacactt cttctttttt gtcaaaattt cctttttctt ctcgtcctat catttggcat
     2581 tctaataaaa acgaactatc cttggatata gaaagagaaa acaaggaggc gtttttcatg
     2641 agtaaaaaat taatcaaagt cggcatcggt ttaggtttgc ttgcccttgg cgctgcatat
     2701 ctaggaaaaa agacaggact attcgaagat gacagtcatt tatatgatga attcgaatca
     2761 atctagcatc ctatttagtt gaatcactac ggacatactt ggaagacatt ggaggaatca
     2821 caatgagaaa aagtaaagca ataatgattg gtgccggtat tgccaatatg gcagcggctg
     2881 tttatttgat tcaagaaggc aaatggaaag gggatcagat caccttttat tcattggatg
     2941 atcacggttc aaatgatggt gcaccgaccg acactgtagt ggatgaatat tggaataaaa
     3001 accatccatt agaaaaccaa aaaggctata ttgctcgagg cggtcgcatg cttaattacc
     3061 gtacctatgt agatttgatg gatctgttaa gtcgaatacc ttctgttact gagccaggga
     3121 tgactgctga agaagatacg agagattttg atgcaaaaca ccgaaccttt gacaaagcac
     3181 gtttgatgga aggtggcaaa ggaatcattg atggcggaaa actgggattc aataataaag
     3241 accgtattct tctgactaaa ctgattgcta tgcctgattc agaagaagaa aaactagaca
     3301 atatcactat cgaagaatat ttcaaagatg atccacactt ttttgaaaca aacttctggt
     3361 ttatgtggga aacaacattt gctttcagaa cacgtagttc tgctcaagaa ttgcgtcgct
     3421 atatgcatca aatgatttat gaattcactc aaatcgaaca tctagtgggc gtcaatcgaa
     3481 cacgttacaa tcaatacgaa agtattatgc ttcctttgat cgagtacttg aaagaacaag
     3541 gatgcaaaat cattttgaac cgccgtgtca ctgactggga attcaaagaa acaccgatgc
     3601 aagatgaaat cactgtgact ggtttgaaaa tgaccaatac actgactcaa gaagaagaac
     3661 acgttgtggt cgatgaagat acagcagtta ttttcactaa tgggtccatt acagattcag
     3721 ctactttagg agattacgaa acaccagctg tagaaaatat ggattatggt gcagcttcta
     3781 gtctctggaa aaaagccagt gaacgtttct acaacttggg aaatcctgac aaattctttg
     3841 ctgatcgaga tgcaagcgaa tgggtcagct ttaccctgac gacgaaaaac catttgttgt
     3901 tgaatgaaat cacccgtatc acgactcaag aaccaggaaa tgccttgaat tcatttattt
     3961 caaccacacc gatcacgccg ttaggccaaa aagatgtcaa tatgtctatc gtcgtgcatc
     4021 atcaaccgca ttttacgtct cagaaaccaa atgaaacagt tatttggggt tatttccttt
     4081 atccaagacg acgtggcgaa tttgtggata aacagtatat taaaatgaat ggaaaagaaa
     4141 tgctagaaga actgattgga caactttcaa aagtagatcc tggaccagtg aatattcgtg
     4201 aaaaagaaac agaaattttc gacagcgtaa taaataatat ccctgtctat atgccttatg
     4261 cttccgcgtt gttcaataat cgtgccaaaa gcgatcgacc aaaagtcatt cctaaacatt
     4321 cgaccaatct ggcctttaca ggagaatttg tcgagcagcc ttatcagatg atctttactg
     4381 aacaaagtgc tgtacgttct ggagaaatcg ctgctttcca ttttgcgggt atccctatgt
     4441 cacgtcttgt caaaacaccg cgttacgaca aagatattcc tactctagct cgtgccgcaa
     4501 aaaaaatgtt tgaataatca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
     4561 caaccaggct aaaacagctt cttatgtttt tgatttggtt ggacttatta ccgcagatgc
     4621 aagcttttga acaccgttta ccaagaggtt gtgaaaaagc tgccctgcat caagtaataa
     4681 gagcagccaa gctaaaacag cttcttatgt ttttgacttg gttggactta ttaccgcaga
     4741 tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa agtcgtttag tttcgagtat
     4801 gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga
     4861 gaaactgatc ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa
     4921 ccattttttc aacgtttact ctcttgccaa tccaacatca tctaacagat acaactattt
     4981 caatgattac cattacacta aaaaatcgga aactcacctc tccgaacaca aatacataag
     5041 actatagaat gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct
     5101 ttaaaatgaa attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc
     5161 atctccaatg aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga
     5221 tgatccaaaa atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg
     5281 cggctccgat ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt
     5341 aggacacgaa ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa
     5401 agggcaacgt gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa
     5461 tcacatggaa agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg
     5521 atttggcaag ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta
     5581 tgcagactct acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt
     5641 tctatcagat attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg
     5701 cgatacagtt gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt
     5761 tatggctgga gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc
     5821 ggctaattac aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga
     5881 attgtatgaa ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg
     5941 attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaaacg gcacaatctc
     6001 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
     6061 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
     6121 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgaaa tgattgcaga
     6181 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
     6241 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
     6301 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
     6361 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc
//
LOCUS       DASHXG010000094         6387 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.101, whole genome shotgun sequence.
ACCESSION   DASHXG010000094 DASHXG010000000
VERSION     DASHXG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.101"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            330..1175
                     /locus_tag="U2R59_002630"
     CDS             330..1175
                     /locus_tag="U2R59_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8966964.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="U2R59_002631"
     CDS             1456..2676
                     /locus_tag="U2R59_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HEM8966965.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="U2R59_002632"
     CDS             2673..5393
                     /locus_tag="U2R59_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8966966.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="U2R59_002633"
     CDS             5377..6321
                     /locus_tag="U2R59_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEM8966967.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DASHXG010000095         6287 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.102, whole genome shotgun sequence.
ACCESSION   DASHXG010000095 DASHXG010000000
VERSION     DASHXG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.102"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..177
                     /locus_tag="U2R59_002634"
     CDS             <1..177
                     /locus_tag="U2R59_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966968.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="U2R59_002635"
     CDS             190..690
                     /locus_tag="U2R59_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8966969.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="U2R59_002636"
     CDS             787..2634
                     /locus_tag="U2R59_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HEM8966970.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="U2R59_002637"
     CDS             2637..3533
                     /locus_tag="U2R59_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8966971.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="U2R59_002638"
     CDS             3583..3972
                     /locus_tag="U2R59_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8966972.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6287
                     /locus_tag="U2R59_002639"
     CDS             3959..>6287
                     /locus_tag="U2R59_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8966973.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITSRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2119 a          933 c         1347 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccag
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaacg
//
LOCUS       DASHXG010000096         6224 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.103, whole genome shotgun sequence.
ACCESSION   DASHXG010000096 DASHXG010000000
VERSION     DASHXG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.103"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(207..1169)
                     /locus_tag="U2R59_002640"
     CDS             complement(207..1169)
                     /locus_tag="U2R59_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEM8966974.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="U2R59_002641"
     CDS             complement(1171..2610)
                     /locus_tag="U2R59_002641"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEM8966975.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="U2R59_002642"
     CDS             2795..4741
                     /locus_tag="U2R59_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEM8966976.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="U2R59_002643"
     CDS             5005..5877
                     /locus_tag="U2R59_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEM8966977.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1988 a         1060 c         1106 g         2070 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatgtatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggaa ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa acgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 aggttctgtt gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata
     6181 gcaggaggaa tgacgatgag tcattttaaa ggaaagcaat ttca
//
LOCUS       DASHXG010000097         6210 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.104, whole genome shotgun sequence.
ACCESSION   DASHXG010000097 DASHXG010000000
VERSION     DASHXG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.104"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(1..520)
                     /locus_tag="U2R59_002644"
                     /pseudo
     CDS             complement(1..520)
                     /locus_tag="U2R59_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            541..1743
                     /locus_tag="U2R59_002645"
     CDS             541..1743
                     /locus_tag="U2R59_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HEM8966978.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2476..3444
                     /locus_tag="U2R59_002646"
     CDS             2476..3444
                     /locus_tag="U2R59_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8966979.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3455..4270
                     /locus_tag="U2R59_002647"
     CDS             3455..4270
                     /locus_tag="U2R59_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HEM8966980.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4338..5048
                     /locus_tag="U2R59_002648"
     CDS             4338..5048
                     /locus_tag="U2R59_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8966981.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5084..>6210
                     /locus_tag="U2R59_002649"
     CDS             5084..>6210
                     /locus_tag="U2R59_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEM8966982.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2110 a          943 c         1262 g         1895 t
ORIGIN      
        1 ctcgtttaac gaaataatag cgtaataatt gacaaaaatg atacgcagtt cgcaattctt
       61 cgttgtagct taacagctca ttaacgattt ctgtttgact aattggtcgt ttaaacagtc
      121 gatgataatg ccgtttgagt gcctcccatg tcgtggaatc tttgagtaag agtttccaat
      181 atcgcttgag ccgacggtac ttcttctgat tttcagagtg tgaggttcga aaacgattca
      241 tgatctggac acgtaattga ttgaagctgc gattgatgtg ttggacaata tgaaagcggt
      301 cagttacgat ctccgcattt ggaaagaccg ttttaagcaa ctgacaatag ctggcattca
      361 tgtccatcac taggtacttg acctttaaac gggcctttct aggaaagcgc aggaagtatt
      421 gagttagttt gtaaagtctg cgatcttcaa gggtcgtaaa tagctgattg gttgtcccat
      481 caacacaaat aaaactcatg gaaccagaag tggcaacatt gtgtactttt ctttgcaatc
      541 ttgtgtacaa aactattgca aaacacagcg cataagaatc cttacaaaac agtagatgaa
      601 gcaacccaat tagatcttgt tatagttgtt aatcagctct taacgggtta cgattcaaaa
      661 tgggtcaaca ccctatactt agataagtca cttgaatatc agaacataat tcaggctttt
      721 tcacgcacaa atcgtcttaa tggtcctgaa aaaccgttcg gaaccattcg ttattatcgt
      781 aaagcacata cgatggaaca gaacattgaa gaggctattg agttatactc aggcaaacaa
      841 gcaaaagggt tatttgttga aaaattatat aataacttag aaaagttgaa cgatatattc
      901 gaagaaatta agtccgtatt taatatttct ggcatagaaa acttcagtca tttaccggag
      961 gttccagggg aaattaagca atttgtaaat ctttataatc aactaatcca ttgttatgaa
     1021 tcagcgatga tacagggatt cacatgggca aaatcgactt atgaaatcca ggattatgaa
     1081 cctataacag tagtaatcac agaatatgaa tttaatatct tggcacaacg ttacagcgag
     1141 atagagagag aacctagaga cggaaatgat agtatagcgt atgacattga ttaccaatta
     1201 cctgaaggta gtcgtagtcg tattaattat gagtatttaa acacaaactt caaaaaatac
     1261 atgaatataa aagaagaacg tgattcgaat ttaattcaat cattgttaaa cgacttacat
     1321 cgcacatttg cgcaattacc agtggagtta cagccatatg ctgagatgat tctaaatgat
     1381 gtaaataatg gggaattagt tatcaaagaa ggatgggaat ttactgatta cctcaatgaa
     1441 tatcagctta gtgaagagga cgattttatc caagatttag tggattcaac caatattaat
     1501 gaggcattat tacgtgagat gttggattta cgcttaaccg aggtaaacat taatgaatat
     1561 agtcgatttg ataaattaaa atcaagtgtt aacgtaggtc atttcagtgg atatatcgag
     1621 aaaaatttag gtaaaatggt aataccaatc aaggtaaata tgctaattga cagattattg
     1681 cgtgcatttt tattagaaga tgtattcgat gttacagagt acataaagaa ttactttaac
     1741 tagagtacac ctacatctta tagtacataa aaaaattcat cttttttagt ttaataattc
     1801 accaaaaagg tgagtaatgc catttttgaa aattgagctt gttttatgtc tacatctgta
     1861 tccgtatata atccaaagga ttataaactc agaagagtct ttattttttc tgaatataac
     1921 tactgtatca aaaacaatcg attatgagac aaaacaaaat gacctctttt atttaagaaa
     1981 ggaggtcatt ttttgtatca taaattgtat taaaatcaat gtatcacttt ttaatcaatt
     2041 ttaagaccat aaattgcgta ctaaaagaaa ttctgcaatt caaaataaag cattttaagc
     2101 cattttcaaa tttaagtgca cccatctacc cgtcaaatca ctttattttc cactccagta
     2161 gtttcctaat tcaactgtgt gcaaaacgat ttcttctaaa caaatcaaga caaacttata
     2221 aaccttcatc ccagcaccat aattatttaa atcataggca tttttcgaaa ttagtatatg
     2281 tactcaagtt tcactgcaga ttatttatat tttttagaga aataaatttt tcctattgac
     2341 aaacacaaag aaagcggata caatacaatt atgtcacatg acgttatatg acgttatgta
     2401 atatctttac atttaatcag ttacttttat tttggataaa attaacattt ttaaaatttt
     2461 aaggaggaaa tgttgatgga tgtagcaaaa acggttaacg caattgtaga aaaaaatgat
     2521 ggagagattt ctggaattta tttggtggct tgtggcggtt cgctggtaga tatgtatgtc
     2581 tcagattatt ttcttaaagc cgaagcatcg aagtgtatta caggcttata tacagcgaac
     2641 gaatttaacc atgtaacccc aaagcaatta gatgataaat ctgttgtcat tctatgttct
     2701 catggaggaa atacagcaga aacggtaaaa gcaggagaag tcgctcaagc tagaggagct
     2761 gtgactgttg gtctgactca taataaaact gcggatttat taaaggtttc tgatcatagt
     2821 ttcctttacg aatggggaga tgatgcaaaa atagtcaata atcctatggc catcattctt
     2881 gatttaactg tatctttggt caatgttacc gaaacatttg aacattacgg taaattcaga
     2941 gaaggcatga aggttatcga taccgtaatt gaaaatggca ttaagcaggt gcaggatcgt
     3001 attaaagtgt ttgctgataa gtacaaagat gaaacaatgt tttatatctt aggtagtgga
     3061 ccatcatatg gacatgctta tggtttttca atttgctctt tgatggaaat gcaatggctt
     3121 gattcaactt ctgttcattc tggagaattc ttccatggac cttttgaagt aacagacaaa
     3181 gatacgaatt ttattctctt gatgagcatt ggacgcactc gtgctttaga tgaacgggca
     3241 aaacgattcc ttgataaata tgcagaaaga gtagaaatcg ttgatgcaaa ggaactagga
     3301 ttggatatga tatcagatga agtttctgaa ttcttcaatc ccattttatt ctacagtatt
     3361 ctttcagaat atcgttcagc tttagcagat gcacgcaatc atgatttaga tgttcgtcgc
     3421 tatatgggga aagtggagta ctaggaggat taaaatgaag gtattaggct taggtgataa
     3481 cgtcgtcgat aaatatgaaa atctgggaat tatgtatcct ggaggaaatt cattgaattt
     3541 tgcagttttt gcaaaaaaac tgggacatga aagtagcttt atgggagttt ttggctcaga
     3601 tgaggaggca gctcatgttt tatcagcaat aaaaaaaata ggactggaca acagtcactc
     3661 tcgctttgaa aaaggcgaga atggctgtgc cagagtgaag attgatgagg gcgaccggat
     3721 tttccttggc agcaattcgg gaggtgttac tcgtgaatac ccgattcagc ttactgaaga
     3781 agacagagaa tatttaaacc agtttgaatt gattcatatg ggattatata gccatgtcaa
     3841 tcatctatta gaagagttac aaaatgtttc tggaaagatt tcttatgatt tttctgacga
     3901 ctttacggaa gaagaggttc agcgggcaat tgataaagtt gattttggct tcttttctat
     3961 agaagacttt tccgatgaag aagtaaagca gtttttgatg aagcattttt gtgagcgaaa
     4021 tgatgtattg attgcaaccc gaggagaaaa aacggctatt ggttatgatg gagcaaagtt
     4081 ttatgaagtg aaccccgtgc tagaagaacc agttgataca atggcagcgg gagattcttt
     4141 cttaacagct ttcctacttt attttctcga aggggacgat atagtcaccg cgatgaaaaa
     4201 ggggaatgaa tttgctggga agtcttgtct ggttgacggt tcgttcggct ttggtattca
     4261 ttacgattga gcttgtttta aattcctgca tttgataacc taaagaaaga aatcccggta
     4321 aagtggaggt taaaaaaatg ctggatacaa atgcacaatt accattgtac ttacaattaa
     4381 aagaaatatt aaaaaataaa atcaatacag gggagtatcc cgagaatacg aaaattcccg
     4441 ctgaatcaga gctgatagaa agttatgagg tcagccgaat cacagtgaga aaagcagtag
     4501 aagaactggt agaagaaggg tacctactta aaaaacaagg gaaaggaact tttgtcaacc
     4561 ggcataaagt ttttcgtaaa attgaatatg ttatgggttt cagtgagagt tgtaaatcta
     4621 atggttttac accgactagc attgttttgg aacgcaagat cattccagca actgaaggga
     4681 tggcaaaaaa actcgatatc gctcaaggtg atgatgtttt atatatccag agaaagcgaa
     4741 tggcggataa catccccatt atgttagaaa acaattattt ttcttatgaa agatatagtt
     4801 tcttaatgga ggaagagctg actgattctt tgtatgaagt acttaaagtc caaggtacct
     4861 tagccatcaa tcctggggaa actgcacttg aaattgtcac agctgatgac caaattgcca
     4921 aaataatgga agtagctgtt gggacgccct ttttctttat ggatacttta atcaacgatc
     4981 aaaacaacat accaattcat gtaggtaatc aatattacct gggagaagta tatcgttttt
     5041 acttatgatt tcctgttttg atttcaagga gtagatttta tttatgaagc aagtattgcg
     5101 gtcaaaaatg atttttgatg gagagcagcc acctttcaaa ggttatattg taatcaatga
     5161 agggatcatt gaaaaggtgg aaaacaactg gaattacagt gatctattaa atgaaaacac
     5221 ggaattaatt gcttatgatg atcaattcgt tatgccagca attcatgata atcatgtatt
     5281 tttcagtggt tatttggcta tgaatgctgg catagattta agcgatacat cttcagctaa
     5341 cgaggctgta gagcgtatta aagctgtaat gaaccataaa aaagcagatg aaccaattta
     5401 tgctcatggc tgggatgctg ccctgtggaa aactgaccca tcagaagagc tattgaatga
     5461 aataaaccac tttggtccaa tcacagcgat cgacaaaaat cgcagccatt gttggatgaa
     5521 tgctattgct aagcagactt atggttttac agaaaaagaa accagtgctg aaagtcgagt
     5581 attattaatt aaggaaatgc tagcaaacaa aaagctttta gcagaggttt acgctgaatt
     5641 tgaagcatta ctgctttcaa aaggtgttat atcaatgaaa gaaatcgttt ttgatgacgc
     5701 agaatttctt tctaatatac ctcagaggaa aatacttagt aacctatatg tgcaggcagt
     5761 ccaagaacct ctacagcatg aacttctata tgagtataag gaaaaagttt tccctgaaaa
     5821 ggtccgcttt ggtggagtga agatcatggt agatggtgtt gttgcggata gaagtggaga
     5881 tatttacggt gtttatcagt caggagtagc ttcacccgag attgactatg aggcaattaa
     5941 agcagaagtt gctgcattca atgaagtaga gattccttgc tgtttgacaa cggaaggaga
     6001 taaagcgggt tataaagctg cgtcaattct tgtcgaattt ggaaagcggt tacctgaagg
     6061 cgtttttaat tcgattagtg atttggaaat ggttactcaa aagacagcag aaaaaatgaa
     6121 cgaaggacaa gtagtagcag aggtatatcc acaaattctc ggcttgaatc aaacgttaga
     6181 agaggcttac atgtcaactg ttataaaaaa
//
LOCUS       DASHXG010000098         6178 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.105, whole genome shotgun sequence.
ACCESSION   DASHXG010000098 DASHXG010000000
VERSION     DASHXG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.105"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(75..245)
                     /locus_tag="U2R59_002650"
     CDS             complement(75..245)
                     /locus_tag="U2R59_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966983.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(260..793)
                     /locus_tag="U2R59_002651"
     CDS             complement(260..793)
                     /locus_tag="U2R59_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEM8966984.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(814..1758)
                     /locus_tag="U2R59_002652"
     CDS             complement(814..1758)
                     /locus_tag="U2R59_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HEM8966985.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2395..2481
                     /locus_tag="U2R59_002653"
     CDS             2395..2481
                     /locus_tag="U2R59_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEM8966986.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(2602..3291)
                     /locus_tag="U2R59_002654"
     CDS             complement(2602..3291)
                     /locus_tag="U2R59_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966987.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3298..3576)
                     /locus_tag="U2R59_002655"
     CDS             complement(3298..3576)
                     /locus_tag="U2R59_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966988.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(3536..4450)
                     /locus_tag="U2R59_002656"
     CDS             complement(3536..4450)
                     /locus_tag="U2R59_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEM8966989.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(4432..4812)
                     /locus_tag="U2R59_002657"
     CDS             complement(4432..4812)
                     /locus_tag="U2R59_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEM8966990.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(5262..5549)
                     /locus_tag="U2R59_002658"
     CDS             complement(5262..5549)
                     /locus_tag="U2R59_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8966991.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(5569..5793)
                     /locus_tag="U2R59_002659"
     CDS             complement(5569..5793)
                     /locus_tag="U2R59_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HEM8966992.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
BASE COUNT         1635 a         1151 c         1042 g         2350 t
ORIGIN      
        1 atttattatt cttttctaag gttaataata ggataatctc tttcagaaag actgctcgta
       61 cgagcagtct tttcttattt atcaagtttt tctacaaata cttcctcatt ttgactgttg
      121 tagtaattag gattgagttt tagttcccct tttttatttc ctttgttggc cactgataat
      181 aacattgggc taaagcttaa tattcctagt aggatagaac cgaatagcaa gtgttttttt
      241 gtcataagta tttccttctt catttccata gctgccacca ttttttccaa ttctttgttt
      301 gttcgtccat tgtttctgtt gcttcagaaa gagtcgttga actattctct gaagactctt
      361 ccgtataagt caactgcagt tgctcctgaa gtttttcgat ttgttggttg gcttgcaggg
      421 tgagttgttg ttgctggtcg agtagttttt gtatatgaga attattttgc tctttgaggg
      481 caagttgttc tcgtaaaaat tcattttctt cacgcaactg atctagcaac ttgtttgcaa
      541 ccacgttttt gtttggtata taagcatttt tatcgttgtt ttgttcatgt ttatgcaact
      601 tatctagcaa cctttgattg tctaagttgc gagcaagttg caatactcca gaacgcaata
      661 caaccttata accacgctca tttttagcta tcatggaaga atctaatttt tggatatgtt
      721 tcgatattgc ttgcctactc atcttaaaaa gatctgacaa ttcctttatt gtaaaggttt
      781 cttgtggttg catactggtt gcctcctagg ttgctactgg aataaattat ctaaatcaga
      841 taataaactt tttttctctt tttccgaaag tgcggactct gtttgttttt caagagcttt
      901 tttctctttt tctagttgtt tgatttgttg gaggagttca agttctcgtt tcttctgttt
      961 gattttttcg ttaattgttg tagcgggttc ttcgtattct ttttgtttat cagctaaagc
     1021 caatgcttta ttttggtctt ctttggttgg tgcatgtttg ttaaagtcgt ctgctttttt
     1081 gatctcaggt ttgaacgtaa attgatagcc aataacaggt tttccccgtc cttttccgta
     1141 tttctttttg attgttagtc ctttgaagat tgcagttagt tcttgacgta taggttttat
     1201 aactcgttta tctatatcag gttgcttata acttttagga atatctaata attcaagaaa
     1261 gtcttctttg gagaaatatg cgaaaccttt ggttctgtat tgctttaaca gacgaaacat
     1321 agtctttgca tagccacttt gtagctcgtt gaattgttgt aaagaatagc gtacccactc
     1381 gtctaaatta tttaacaaag gcagtgcttt ttcgtaaatt cgtatatcta cgtaaggatt
     1441 ttctacgtcc ccgttgattt taaattctgt aaacattaca aacatatcgt aagaaagccc
     1501 agactcactt ctacgaccaa agcgtaaaga taagattttt tcataagttg cttttaaatc
     1561 ttctacaaat cgtacatttg cagttgcttt gtagttactt aaatctttta gttggtcaaa
     1621 cgtaaaacga actgtcttat cccctttttc acgcattcta gacacgatgg aaaaaaacaa
     1681 attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat ggtggtattt
     1741 tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt ttttaaatgt
     1801 caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca gacaaaatgt
     1861 ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca taacattctg
     1921 tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag aggtttaaaa
     1981 agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt ttttctttaa
     2041 acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac ggtcgccaaa
     2101 aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc tcctttgcta
     2161 aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag ccgttttaag
     2221 acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg tcagggcaag
     2281 ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa ttttttaaga
     2341 tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta tctaatgttt
     2401 gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag ttattggttg
     2461 aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa aaagccccag
     2521 agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc atgtttagtt
     2581 taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt ccttgacact
     2641 ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg ttgcttgctg
     2701 aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc gttcctgttc
     2761 actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt ctgtctgcgt
     2821 atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa cctctttttg
     2881 ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt tatccgtcaa
     2941 acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg taaactcttc
     3001 cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt catacttttg
     3061 agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta aaacgccgaa
     3121 taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa acctcttaaa
     3181 tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc taagccaaat
     3241 aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca tttctattta
     3301 ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata agggggcaag
     3361 aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct ggtttaatag
     3421 cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt ctttggtata
     3481 aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta acgttttaga
     3541 acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg tttcttcgag
     3601 tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt acttcttttg
     3661 cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt tgattgtagg
     3721 ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc tttcctagtt
     3781 tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt ttcccacgat
     3841 tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac gttcgagttt
     3901 ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa acaggttcat
     3961 ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc cctcgttcag
     4021 tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat ttgtttaaaa
     4081 atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag ttaatgacaa
     4141 tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg tggtcagggg
     4201 ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta atttctcctg
     4261 gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca tacagcatgc
     4321 gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct gttttgacgg
     4381 ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg cttactttaa
     4441 ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg ataagcgttg
     4501 ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa tttgattgat
     4561 attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg gcgccacttt
     4621 cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca cactcatttg
     4681 caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc gaaaactgat
     4741 ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca aatattgatt
     4801 ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt tcgcaatacc
     4861 attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag ggcttggcaa
     4921 gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct tgtcaaaggg
     4981 gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa aaagactagc
     5041 aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa ttgttgcaaa
     5101 tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg ccatttacta
     5161 ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac tgatgaatca
     5221 gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca aataccaata
     5281 gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa ttctattaaa
     5341 gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact acttaatttc
     5401 atactaactt caccaacact ttttccctca ctgatttctt tagaataaag aaagagcttt
     5461 tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact aattgcattt
     5521 aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact accttctagg
     5581 tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt ctcctttagc
     5641 ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc catagtaagt
     5701 agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta atattcctag
     5761 aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc gtttttttaa
     5821 aattgcttgt tatattaaat aatcttagta attttattat ataacatttt attatataac
     5881 aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa aattataaga
     5941 tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg cctgtaccaa
     6001 gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct ctttttaagg
     6061 cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg tcatttttta
     6121 aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata ttcattta
//
LOCUS       DASHXG010000099         6110 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.106, whole genome shotgun sequence.
ACCESSION   DASHXG010000099 DASHXG010000000
VERSION     DASHXG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.106"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(559..1599)
                     /locus_tag="U2R59_002660"
     CDS             complement(559..1599)
                     /locus_tag="U2R59_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8966993.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="U2R59_002661"
     CDS             complement(1948..2274)
                     /locus_tag="U2R59_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966994.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3064)
                     /locus_tag="U2R59_002662"
     CDS             complement(2261..3064)
                     /locus_tag="U2R59_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEM8966995.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3417..3707)
                     /locus_tag="U2R59_002663"
     CDS             complement(3417..3707)
                     /locus_tag="U2R59_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HEM8966996.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3843..4022)
                     /locus_tag="U2R59_002664"
     CDS             complement(3843..4022)
                     /locus_tag="U2R59_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966997.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4019..4369)
                     /locus_tag="U2R59_002665"
     CDS             complement(4019..4369)
                     /locus_tag="U2R59_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8966998.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4362..5687)
                     /locus_tag="U2R59_002666"
     CDS             complement(4362..5687)
                     /locus_tag="U2R59_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HEM8966999.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            complement(5856..>6110)
                     /locus_tag="U2R59_002667"
     CDS             complement(5856..>6110)
                     /locus_tag="U2R59_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8967000.1"
                     /translation="AAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLK
                     TLVDSGTPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         1822 a         1126 c          891 g         2271 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
     3181 ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta ctttaaaatt
     3241 ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt aaacattact
     3301 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
     3361 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
     3421 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
     3481 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
     3541 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
     3601 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
     3661 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
     3721 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
     3781 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
     3841 ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc tgcagcttct
     3901 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
     3961 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
     4021 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
     4081 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaatga
     4141 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
     4201 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
     4261 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
     4321 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
     4381 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgccttct
     4441 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
     4501 attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa atccagctga
     4561 agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac ttcttgtcct
     4621 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
     4681 atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg
     4741 tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc
     4801 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
     4861 tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat atctgttcga
     4921 tcgatcccat tagcatggaa gtacagctgt aatccaatca cacctaatct attcttaatc
     4981 gtataaggat tccagttagc aaggtctcta atgctcaaaa ttcccatttg gttgagcctt
     5041 tttttcattc gcgaaccaat tccccaaaag tccgtcattt cgggaatatt ccatactttc
     5101 tcaggaacgt tttcgtacgt ccattccgca ataaatcctt cattatgctt tgcttcattg
     5161 tctaaggcta atttagccaa aaggggatta tcgccgacgc ctaccgtagc aatcaaacct
     5221 aactcttctt taatacgttc ttggatcatt tgagcgagct tcttccttcg ctgacttcgt
     5281 gtttcttcag tcgtaaaaag attcagtgat tttgtcactt ttaaaatcga ttcatcgatc
     5341 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     5401 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     5461 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     5521 gaagaagcta atatcaatcc tgaaccagta ttatcagatc gactcataac aacaagttct
     5581 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     5641 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     5701 ttcttccaca ttatacaaac atatgttcga tgttgtaaag aagaaatagc taaatatttg
     5761 agaataagtt atcagtagac acttacaaaa aattctcata ctattgtcac ttttctagat
     5821 aaatggcaaa aattttcagc attaaatgac aaaaactaat gagaatttgt ctttccattt
     5881 ttctcctcca tttttgccaa ataacgataa atggtggttc ttgagacgtt ccaccgttcc
     5941 gcaatagtct taataggtgt accgctatcc actaaagtct tcagtaattc caaatcttgt
     6001 tcagacaatt tttcaggacg accaccaaac cgtcctcttg cacgagcagc tgctcgtcct
     6061 gctgcggatc gttccaggat caaattacgc tcaaattctg caaatgccgc
//
LOCUS       DASHXG010000100         6055 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.107, whole genome shotgun sequence.
ACCESSION   DASHXG010000100 DASHXG010000000
VERSION     DASHXG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.107"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            822..1556
                     /locus_tag="U2R59_002668"
     CDS             822..1556
                     /locus_tag="U2R59_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEM8967001.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1572..2741
                     /locus_tag="U2R59_002669"
     CDS             1572..2741
                     /locus_tag="U2R59_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEM8967002.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2757..3752
                     /gene="lacD"
                     /locus_tag="U2R59_002670"
     CDS             2757..3752
                     /gene="lacD"
                     /locus_tag="U2R59_002670"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEM8967003.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3831..4757
                     /locus_tag="U2R59_002671"
     CDS             3831..4757
                     /locus_tag="U2R59_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEM8967004.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4776..6026
                     /locus_tag="U2R59_002672"
     CDS             4776..6026
                     /locus_tag="U2R59_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEM8967005.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2023 a          995 c         1242 g         1795 t
ORIGIN      
        1 cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta actttaactg
       61 ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac aatcggaata
      121 gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt gccattccaa
      181 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
      241 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      301 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      361 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      421 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      481 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      541 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      601 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      661 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      721 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      781 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      841 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      901 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      961 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
     1021 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
     1081 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
     1141 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1201 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1261 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1321 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1381 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1441 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1501 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1561 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1621 ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1681 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1741 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1801 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1861 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1921 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1981 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     2041 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     2101 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     2161 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2221 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2281 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2341 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2401 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2461 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2521 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2581 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2641 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2701 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2761 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2821 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2881 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2941 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     3001 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     3061 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     3121 atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc aatcggcaaa
     3181 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3241 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3301 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3361 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3421 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3481 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3541 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3601 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3661 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3721 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3781 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3841 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3901 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3961 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     4021 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     4081 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     4141 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4201 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4261 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4321 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4381 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4441 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4501 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4561 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4621 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4681 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4741 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4801 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4861 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4921 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4981 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     5041 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     5101 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     5161 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5221 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5281 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5341 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5401 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5461 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5521 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5581 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5641 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5701 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5761 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5821 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5881 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5941 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     6001 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agtta
//
LOCUS       DASHXG010000101         6029 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.108, whole genome shotgun sequence.
ACCESSION   DASHXG010000101 DASHXG010000000
VERSION     DASHXG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.108"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(68..370)
                     /locus_tag="U2R59_002673"
     CDS             complement(68..370)
                     /locus_tag="U2R59_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967006.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="U2R59_002674"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="U2R59_002674"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="U2R59_002675"
     CDS             complement(1127..1900)
                     /locus_tag="U2R59_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEM8967007.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="U2R59_002676"
     CDS             2044..2394
                     /locus_tag="U2R59_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEM8967008.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="U2R59_002677"
     CDS             2375..3091
                     /locus_tag="U2R59_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8967009.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="U2R59_002678"
     CDS             3091..4539
                     /locus_tag="U2R59_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8967010.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="U2R59_002679"
     CDS             complement(4610..5119)
                     /locus_tag="U2R59_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967011.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="U2R59_002680"
     CDS             complement(5109..5834)
                     /locus_tag="U2R59_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967012.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DASHXG010000102         5709 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.110, whole genome shotgun sequence.
ACCESSION   DASHXG010000102 DASHXG010000000
VERSION     DASHXG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5709)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5709)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5709
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.110"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..193)
                     /locus_tag="U2R59_002681"
     CDS             complement(<1..193)
                     /locus_tag="U2R59_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967013.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFE"
     gene            complement(736..2886)
                     /locus_tag="U2R59_002682"
                     /pseudo
     CDS             complement(736..2886)
                     /locus_tag="U2R59_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            3032..3607
                     /locus_tag="U2R59_002683"
     CDS             3032..3607
                     /locus_tag="U2R59_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967014.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3821..4516
                     /gene="vanR"
                     /locus_tag="U2R59_002684"
     CDS             3821..4516
                     /gene="vanR"
                     /locus_tag="U2R59_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEM8967015.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4494..5648
                     /locus_tag="U2R59_002685"
     CDS             4494..5648
                     /locus_tag="U2R59_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEM8967016.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1786 a         1096 c         1083 g         1744 t
ORIGIN      
        1 gttcaaaatc taaaatcaac acatcatggg gagtgtgata ataaatattt tcccttaatg
       61 taccaacaat ggtaattcgg tcaattgacc attgcatttt taagggggtg cacatagttt
      121 gtgcatttaa ccgcctgtta gaaatacggt taagtttttc ccactcattt acgattatgc
      181 cttttttact caaaaatagc tcctcctcaa cgaaaaaaga gattcttgga aagaatttcc
      241 agagttcacg taactctaaa aatccacatc caaaaatctc tagcttgaag aaacctaaaa
      301 atattcgtat aatgaacttg agttacggaa ctaggtgaag tagtttccgt aaaggtcgag
      361 agtgcgtcaa cactgctcga ctattttttt actctttttt ctcattttct ttgattatag
      421 cactcctcta gaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc
      481 tcctcctgcc gaaatagaat ggcgctgcca gcatttattt cgttcagcta tcggctacac
      541 aatctaacac gaccgttccg ctaccagtcg ccttacaggc tccattttcg ctcctctaac
      601 gtgtttcacc gattgtgccg ataactaaac gaaataaacg ctaaaaccgc tcagaacgca
      661 aaatatgcca ttttagagct attgtagaaa atatagtttg aaatgcaatt ttcttctttc
      721 agctttttat ttcccacttg taaatcggta gatggtggct ccttttccag ttccataatg
      781 tggatttgca tctgcatgta gtgatgaaac acctagctgc attctcatac catctgacga
      841 agatgttgta ccgtcgcccc aatagaaagg caattgtaat ttatgatgaa agtttactaa
      901 tatggcttgg gctttattca tggcatcttc atacatgcgc cattgagata cattggctag
      961 ttgcttatat gtaagtccgg gtgtggcttc ggccatcttg ctcaagccaa tattcattcc
     1021 cattcctaaa agggcagcca tgataatgat tgtttcttcc ttatctggtt ttcgattatt
     1081 ggaagcatga gtgaattgct catgaaatcc tgttatatgg gccacatcca tgagtaaatc
     1141 agttaatttt attcttggta gcatctgata aaggcttgca ctaaattttt ttgcttcttc
     1201 tggaacatct ttttctaagc gtgcaagtga tagctttcct ttttcaagag aaaccccatc
     1261 taacttattg gaattggcag ctaaccactt taacctttca ttaaagctgc tggttctctc
     1321 cgttatataa tcttcgaatg ataaactaac tgataatctc gtattcccct tcgattgatt
     1381 ccatgtatct tccgaaaaca aatattcctc aaaatcccta tattgtctgc tgccaacaat
     1441 ggaaacatct cctgcccgaa catgctcccg aagttctgtt aaaacagcca tttcatagta
     1501 atgacgatta attgttgtac catcatcctc gtataaatgt cttttccatc gttttgaaat
     1561 aaaatccaca ggtgagtcat caggcacttt tcgctttcca gattcgttca ttcctcggat
     1621 aatctcaaca gcttgtaaaa gtggctcatt tgcctttgta gaatgaaatt ccaatactct
     1681 taatagcgtt ggcgtatatt ttcttagtga ataaaaccgt ttttgcagta agtctaaata
     1741 atcatagtcg gcaggacgtg caagttcctg agcctcttct actgaagaga caaaggtatt
     1801 ccattcaata accgattcta aaaccttaaa aacgtctaat ttttcctctc ttgctttaat
     1861 taatgcttgt ccgatgttcg taaagtgtat aactttctca tttagctttt taccgttttg
     1921 tttctggatt tcctcttgag ccttacgacc ttttgataac aaactaagta tttgcctatc
     1981 atgaatttca aacgctttat ccgttagctc ctgagtaagt tgtaataaat agatggttaa
     2041 tatcgaataa cgtttatttt cttgaaagtc acggaatgca tacggctcgt atcttgagcc
     2101 taagcgagac agctgcaaca ggcggttacg gtgcaaatga ctaatttgca ctgtttctaa
     2161 atccattcct cgtatgtatt cgagtcgttc tattattttt agaaaagttt cgggtgaagg
     2221 atgacccggt ggctctttta accaacccaa tatcgtttta ttggattcgg atggatgctg
     2281 cgaggtaata atcccttcaa gcttttcttt ttgctcattt gttagagatt tactaaccgt
     2341 attaaatagc ttcttttcag ccattgccct tgcttcccac accattcttt caagtgtagt
     2401 gatagcaggc agtataattt tgttttttct tagaaaatct atgcattcat gcagtagatg
     2461 aatggcatca ccattttcca aagctaattg atgaaggtac ttaaatgtca ttcgatattc
     2521 actcagggta aaagttacaa agtcgtattc acttcgaatt tctttcaaat gatcccaaag
     2581 tgtattttcc ctttgaggat aatgatcaag cgaggatgga ctaacaccaa tctgtttcga
     2641 tatatattgt atgaccgaat ctgggatgct tttgatatga gtgtatggcc aaccgggata
     2701 ccgaagaaca gctaattgaa cagcaaatcc taaacggttt tcttccctcc ttcgcttatt
     2761 aactatttct aaatcccgtt tggaaaaagt gaagtaggtc cccagtatcc attcatcttc
     2821 agggatttgc ataaaagcct gtctctgttc cggtgtaagc aattctctac ctctcgcaat
     2881 tttcattcag tatcattcca tttctgtatt ttcaatttat tagttcaatt atatatcaat
     2941 agagtgtact ctattgatac aaatgtagta gactgataaa atcatagtta agagcgtctc
     3001 ataagacttg tctcaaaaat gaggtgatat tttgcggaaa atcggttata ttcgtgtcag
     3061 ttcgactaac cagaatcctt caagacaatt tcagcagttg aacgagatcg gaatggatat
     3121 tatatatgaa gagaaagttt caggagcaac aaaggatcgc gagcaacttc aaaaagtgtt
     3181 agacgattta caggaagatg acatcattta tgttacagac ttaactcgaa tcactcgtag
     3241 tacacaagat ctatttgaat taatcgataa catacgagat aaaaaggcaa gtttaaaatc
     3301 actaaaagat acatggcttg atttatcaga agataatcca tacagccaat tcttaattac
     3361 tgtaatggct ggtgttaacc aattagagcg agatcttatt cggatgagac aacgtgaagg
     3421 gattgaattg gctaagaaag aaggaaagtt taaaggtcga ttaaagaagt atcataaaaa
     3481 tcacgcagga atgaattatg cggtaaagct atataaagaa ggaaatatga ctgtaaatca
     3541 aatttgtgaa attactaatg tatctagggc ttcattatac aggaaattat cagaagtgaa
     3601 taattagcca ttctgtattc cgctaatggg caatattttt aaagaagaaa aggaaactat
     3661 aaaatattaa cagcctccta gcgatgccga aaagcccttt gataaaaaaa gaatcatcat
     3721 cttaagaaat tcttagtcat ttattatgta aatgcttata aattcggccc tataatctga
     3781 taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata aaatacttat
     3841 tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa acgagaatta
     3901 tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca agtctgagat
     3961 tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta tctgtcaaaa
     4021 aataagggac aagcacacct atccgattat catgctgacc gggaaagata cagaggtaga
     4081 taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct ttcgcccact
     4141 ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca gtggagtaaa
     4201 ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta acacccatga
     4261 gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa tactgcgaat
     4321 cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg agatatgggg
     4381 cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc atttgcgcga
     4441 aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg gggttggtta
     4501 taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt tacatgtata
     4561 tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca atgatccgag
     4621 ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta aatcacctgg
     4681 acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt atttatgtgg
     4741 cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc gcaaaatact
     4801 ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa caaattgagc
     4861 tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg actctggaaa
     4921 agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt atgtacttgg
     4981 cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg cttgacgagg
     5041 ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg gacaaagcgt
     5101 atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac ctacaaacga
     5161 taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg accgatgaat
     5221 tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc gaggatctga
     5281 ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg aaaaacgccg
     5341 ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc ggggatgtgg
     5401 tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct gccatatttg
     5461 aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg ggacttggat
     5521 tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg gaaagcaatg
     5581 ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt gataaaagga
     5641 ggtcctaaga gatgtatata attttggctc tttgtcaaat gatgttggta aagagaaatc
     5701 ttagaataa
//
LOCUS       DASHXG010000103         5491 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.111, whole genome shotgun sequence.
ACCESSION   DASHXG010000103 DASHXG010000000
VERSION     DASHXG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.111"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..78)
                     /locus_tag="U2R59_002686"
     CDS             complement(<1..78)
                     /locus_tag="U2R59_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8967017.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNL"
     gene            complement(171..566)
                     /locus_tag="U2R59_002687"
     CDS             complement(171..566)
                     /locus_tag="U2R59_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967018.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(556..768)
                     /locus_tag="U2R59_002688"
     CDS             complement(556..768)
                     /locus_tag="U2R59_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967019.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1840..2442
                     /locus_tag="U2R59_002689"
     CDS             1840..2442
                     /locus_tag="U2R59_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967020.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2797..3033
                     /locus_tag="U2R59_002690"
     CDS             2797..3033
                     /locus_tag="U2R59_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HEM8967021.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            3030..3443
                     /locus_tag="U2R59_002691"
     CDS             3030..3443
                     /locus_tag="U2R59_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEM8967022.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3962..4912
                     /locus_tag="U2R59_002692"
     CDS             3962..4912
                     /locus_tag="U2R59_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HEM8967023.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4909..>5491)
                     /locus_tag="U2R59_002693"
     CDS             complement(4909..>5491)
                     /locus_tag="U2R59_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967024.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1953 a          788 c          923 g         1827 t
ORIGIN      
        1 tagattgtaa cgcaggtagt aaccaacagc gacaataatg acgtcttttt tgaattgttt
       61 gcctttaaaa tgattcatta ctctgtcctc tctgtctttt ttctcaattt tacactaaaa
      121 tagatttttt ggaaaacttt gcaacagaac ctttgtatga acctttattt ctacattttt
      181 ttctcaagca cactactgat aatgattaaa ataatcggct ggattgcaat gatacttccg
      241 acaataatag ctggaatgat gtagtctaaa caaataaata taactgttgc cacccctaac
      301 agtattgtgt taaacatatt tgttatattt cccgcttttt ctttgattat gatattccgt
      361 tcgtccataa cattgatttt gtagtctgca tcatttttaa tcattttatc atgcaaaatt
      421 tgaacatgag aaacgccaaa aacggcactg aataaaatag caagtccaat atctaccatt
      481 ttaggaaaat ctgtaaccaa aattgtcaca atcaaaaaca acgaaacaat ataaccgata
      541 taccaaatct gacccttatt tttcatcttc actttcctcc tcatagataa aaatttcttc
      601 aatgctcatt tgaaagtacc ttgcaatttt aaatgccaat ataatagagg gattataacg
      661 tccattttct aaagaaccta ttgtttgacg agatacttca agagcagaag ctaaatcttc
      721 ttgtttaatt cctctttgtt ttcgtaattc ttccaaacga tttttcacaa catgctcctt
      781 tctaaaaaat ggaaagttta ctttcctttc gtgcttttat aatactcctg cgagcacaaa
      841 atgtcaagga agctttccat ataaattttg attttaatgt tttagttact gtttttatga
      901 cacatgaaca cacttattct tatttcctct tatctgctat caacagaaaa gaaaaagccc
      961 tgtcaagagc cgattagatc aagccagtcg agaaacgatg ttagaccaaa ttgattttgg
     1021 gtaatgaatg tttagaactt agtagtcatc caaaaacgac tacttttttt gttgaatcgt
     1081 ccaaggacga ttcgatgctt ttgacttgta agaacaggat tgaatgaaac catactgttc
     1141 gcatattttt agtggatgaa caaacaaaat acgagagatt ttttgttcgt tcatccatgg
     1201 ttttagaaaa aagagggacg attttggaag aagaaaatcg tctctttttt ttcttctttt
     1261 tgtatgacaa aaagaaagat cttttgccca ttttattttt ataaaatggg taggtggcgt
     1321 tcgcgtaaag caaatcgata caatccaatg gttttggcga atcagattta ccattctagg
     1381 cttgtttaat acagacatcg attgttattt tgagaattta tatccttatt ggcaatgaaa
     1441 tggatattct ccataccaat agaaatcttc aagataattt tcggaaatat ataagagtta
     1501 atcaattatg atcatatagt aggtaaaaat taggacagcc ttcaattata tgggaaacca
     1561 atataatcaa gtaattattc gggtaacaca aatactagag tactcatttc ttataactgt
     1621 tttacaccta ttagggatca gtattattaa tagatctaga taaattaata cgtaattata
     1681 taataattta tgtttgtgcc attaaacaat cttaacagat atttcatttt atttatgtaa
     1741 aacaacacga ataattattg cttcgtaaag ttatatgagt ataagttaat ttactggagg
     1801 tagtgcaatg cttttttctg aaagatttgg ttttaaaaaa tggaggatat catactgaga
     1861 gatagattga cagaccctct taaaaatagt ttagcaaatg tgatttatga tatattacga
     1921 gaggctgata aagtttatag taattataat ggaaaagtct catgggtaat atattctttt
     1981 ttaattaaag agttttttaa agaacagata aataatagct atgagttggg ttatcatttt
     2041 actgtttatt atgaagatat tatcaagagg ttagaagact tggagtggta tgcttattat
     2101 gatttattag aggtttttgc aagtgctaaa atcttggata aaaagaaaag agaggaagta
     2161 aataaaattc tggagtcgga aaattctggt tacagattaa gcgaaagcaa tgaatttatt
     2221 ccaatcacag atgatatttc tattaagtct ataaatgctg tatctgaatc accatttaat
     2281 tacgcaaaaa atcatatcca taaatctctt acatatataa gcgagaagga aaatcaagat
     2341 tataatactg tagtgagaga agcaattagt gctgtcgaaa gttgtcttat cgaattttca
     2401 ggattaccag ctaataaaaa aatactttgg gaactgctat aaaagcaatt aaagacaaat
     2461 cgaataacaa tgtcgatctt acatttttaa aaccatttga gacaatgtat ggtttggcga
     2521 gtaataatgg aatacgacat gcagaaaatg aaaaaacaat tgtctcagat ttacctgatg
     2581 cagttttggt gttaacaaca tgttcagccg taattaatta tttgggagta aaaatagcat
     2641 atgactccaa taaatcatga aaagttaaaa ttcatccaag agctacatta taactattaa
     2701 tttccaactc tttaaaagtt tagtaattga aggaagtaat aagggtgatt gaacaatacg
     2761 gatatacggt gtatacttat cgtaggagtt gatgatatga atattaaaaa acgcaaaatc
     2821 agagaagtag gtaattcaat agttgtaact ttgtcaaaag agagtttatt gcaaaaaggt
     2881 ttgaaacctg gagatactat ttttattgat gaagataaaa tgatggaagc tattgtaaaa
     2941 gaggaaagca agatagatct tgaaattgat atgtatgtta accaagcttt atctgagtat
     3001 gatgcagctt tcaaggaatt agttgaaaaa tgatctatct aagtgaaaaa gatattgtaa
     3061 aattgaatgt tattcaaata aagaaatatt caccgcgaga aacaatcgga gtcattgaca
     3121 aaaatgcgct gagtatggct gtaaatcaac ctaaacagca tatttttgga aaagatctgt
     3181 atcctgataa atttagcaaa gcagctgttc tgctaataaa tctgatcaaa aagcatccat
     3241 ttcataatgc taacaaacgt acagcatttt tagccgcgta tgtttttctc aagctaaatg
     3301 gctattcact aaaaatgaaa aatcaggaag tagtagaatt tgtagttgaa attgctacgt
     3361 atcagggtga ttttgatgac ttaaaagagg caacaacaga tatactaaaa aagaattcaa
     3421 caaagaccga ttcaaaaaag tagaagcaaa ctagggattc agttaaatct gaagatttag
     3481 tttgttcttt attttagttt acataagata cattatgcga agttcattat tttaaaagct
     3541 taaataataa acttttttat aataccaatt tatttatgta aaccaatgac cttaatcgct
     3601 taagcaagca tgttatgtaa tactctactc tctccaaaac taatgactat ctattttcaa
     3661 agaagctaga atgattatct gatcaaatga taatttatat ttaattcctg gtctactgct
     3721 cttcttttaa tcaattaatg tctaacgtac tgtacacgat aaagtaggaa gacttatttt
     3781 caacttcgga ttcatttttt taattcggtg aaaatcacta aattaagagt ttatccaagt
     3841 tcattttagc tgagaatacg cttgaaaata attttgatga attttcctga attaaaattt
     3901 attaacttgt tgagtgatat aattgtaatg tattaccaaa tagttagcac ttagattagt
     3961 gatggaaagg aatagtgaga acaagatgac tggtagaaat cccaaagtat ttatatcata
     4021 ttcatgggag aataaggaaa ataaagaatg ggctagagaa ctagcagaca aattacttga
     4081 aaacggtatt gatgcatata tagatcagta tgatttaagt ttaggtgata gattacctca
     4141 gtttatggag cagcaaatat ccgattcaga ttatgttcta attatatgta caccagagta
     4201 taaaaaaaag gcaaataatc gtacaagtgg tgttgggtat gaaggtcata ttatctcagc
     4261 agaattgctt tctggaaaaa atgaacgtaa atttatccca ataattaaag aaggacgtgc
     4321 aagcgaagta cttcctactt ttcttgctgg aaagcttgga attgatttat cagatagcca
     4381 gcattatgat gaaaacttag atgatttaat tacaactata tttggtgtta agagaaaacc
     4441 agcattaggt gatataccta ggcatattaa aggcagtcct ttactaccta tagaacataa
     4501 tgaaaataaa gatattgaaa tcttaggaat tatcactgat aaagtaactg tacctaaaat
     4561 ggatggctca aggggttctg cattatataa aattccattt agattaaata gagtaccaag
     4621 tcagctttgg aaagagttgt ttgttagaaa ttggaattca ccaccacgat atacaacaat
     4681 gcatagacca ggaattgctt ctgttgtaga cgatgaaatt ttacttaatg gaacaactat
     4741 tgaggaagtc cgggaatatc atcgggaaac tttaaaactt tgcattgaaa aaagtaatac
     4801 tcaagaaaaa aaaatattgc tagaggagga acaaaaaaaa gagagagaga atgagcgagt
     4861 cagatcacat aaagaaagtg ttcagaaatt agcagatgaa ttagagttct agttgatagt
     4921 cagttctttc ttaattcgat acacagtttg tctagttaca ttatagtctg ttgctatttt
     4981 tgaaatagca acaccattct cctggtcctg aacgatgctt ctataaacaa ggcgacgttg
     5041 aggatctttt gtgttcgcac tgtataactt aggacgtcct ttatagacgc cgtttgcttt
     5101 agcaatcttt atcccttgtg cctggcgtcg ttttgattca gtacgctctt gttcagcaat
     5161 catggccaag atttgaatga ttaggtcttt gataaattta tccaggagag gatttccgat
     5221 tgcttcagcc atgatcggta aattagtgat aataagtcgc acatttttct tctttagata
     5281 atttactgaa tcgataatct cgtcataatt acgtccaagt cgatcgatag cctctacaat
     5341 aaaaatatct tggtctctaa caaaatctag aacttcctga aaaatcggtc gatgagtaat
     5401 agtcgctcca gattgtttct cgatgaaaat tttttcagca ccaaattttc tcatttcctc
     5461 gatttgacgt tgttcatttt gatcgatcga t
//
LOCUS       DASHXG010000104         5463 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.112, whole genome shotgun sequence.
ACCESSION   DASHXG010000104 DASHXG010000000
VERSION     DASHXG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.112"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..921
                     /locus_tag="U2R59_002694"
     CDS             <1..921
                     /locus_tag="U2R59_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967025.1"
                     /translation="DDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQANMEEEFVLGQ
                     TYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTPQKVGVNYPKRL
                     TIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYT
                     EKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYAT
                     FIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPSGTSSVSKAMYV
                     RKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            924..1370
                     /locus_tag="U2R59_002695"
     CDS             924..1370
                     /locus_tag="U2R59_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967026.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            1372..1509
                     /locus_tag="U2R59_002696"
     CDS             1372..1509
                     /locus_tag="U2R59_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8967027.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            1546..1839
                     /locus_tag="U2R59_002697"
     CDS             1546..1839
                     /locus_tag="U2R59_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967028.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            1862..2059
                     /locus_tag="U2R59_002698"
     CDS             1862..2059
                     /locus_tag="U2R59_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEM8967029.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            2070..3089
                     /locus_tag="U2R59_002699"
     CDS             2070..3089
                     /locus_tag="U2R59_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HEM8967030.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            3346..3993
                     /locus_tag="U2R59_002700"
     CDS             3346..3993
                     /locus_tag="U2R59_002700"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEM8967031.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            4276..4349
                     /locus_tag="U2R59_002701"
     tRNA            4276..4349
                     /locus_tag="U2R59_002701"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4310..4312,aa:Ile,seq:cat)
     gene            4895..>5463
                     /locus_tag="U2R59_002702"
     CDS             4895..>5463
                     /locus_tag="U2R59_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HEM8967032.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1934 a          853 c         1083 g         1593 t
ORIGIN      
        1 gatgaccctt actggctagg taaagcgcct ttgggtgaga atattgctaa taagtctgtt
       61 acgtttccaa tcaaatctag cgcctacagc ctataccaag ctaacatgga agaagaattt
      121 gttttaggtc aaacctatac aattaccatg aaggcaacca aaccacctat ccaaacgttc
      181 attgtttaca acgaggatag tggagattat agatatggta acttagagcc agtagaaggg
      241 ttagttgata catggggtct gacttttaca ccgcagaagg ttggagttaa ctaccccaaa
      301 cggttaacta ttatccagta tccccaatca acaacaggtg catgtcaaat tgactggctc
      361 aagatcgaaa aaggcgacac acgaaccccg aatattagtc agtttaaata ctttggtgaa
      421 ggcttgaaag acagtaacaa tcccaatgat tacagttggg atgtcacacc tgaatatact
      481 gaaaaaggct tgaatgatgc tgttaatgtg tatgatcctc agagagttga aggtttgaaa
      541 aactttgccg atggtattca aatagcagga gataaagtga tcagtgaaaa tgattgcact
      601 gtttatacat taactaaaga caacagtcaa tcgtttatcg atgggtatgc aacatttatt
      661 aaacacggaa aagaagttat tgtaaatggt acagtaaagt tcaaaaaagc ttatgctttt
      721 ggtgtaccac ttgatgatga agtcccagat gaatttgtcg caaaaattgt tcatggcatg
      781 cttacaggtc cgtcaggaac aagtagtgta tcaaaagcga tgtacgtgcg aaaagactta
      841 ggaacaatta ttacgaatag cgaatttgct gcaaatgaat ggtttacatt ccatggtaat
      901 tattgggtag gggaggaata aaaatgaaaa atatttggaa atacggacga acaggtggag
      961 agtatgctgg acaagtgctt gatgatatgg ttatgactgt tccatttacc gatgttccac
     1021 cactcgaagg aattcgtgct gatggggaac cactaacgat tgctgatcag atgtttgatc
     1081 ctaaactgaa ccaatggatt gttttagtga atgtactaga tcacaacgat ttaaacaatc
     1141 tcaaagcgat gtatgagtcg ttagaaaatg agaacggcga tttaaaacag ctcaacgcca
     1201 aactcatgct aagcgatgta gcgattaaac aggaaaatac tgcattgaaa gaaaaagcgg
     1261 atggtttagc acaaatcaat tcaaaaacga tgcttgcttc gttccaaaat agcaaagaca
     1321 ttgcagaaat taaagagcaa ctaaatccag cttcaaaggg aggtgagtag tatgtttagt
     1381 tttagcgatg tgaaaatgat gtatgattgg ggctgtttta ctgacgatca agttcgacta
     1441 ttcgttccac tatgcattac agacgaagaa gcagaaaaaa tcattaataa agataagagc
     1501 gcatcttaag tgatgcgttt ttatttaagg taaaggagtt gtcacatgat taatttagga
     1561 gaatggggaa caatcgcagg atcaatcact gcgattgttt ctttgatttt attagtaata
     1621 agaccagtca ctgcatcttt ctcgaagatt actgaaactc tttcaaaagt aagtcacaat
     1681 ttagatttgc tgactaaaga tttagaatcg agcaaatcag atcgattgat gattcatgaa
     1741 gaactaaaga aacacgatga aagattagat acacatacag aaaaattggt agaacacaca
     1801 caacaaatca aaactttatt tagagaaaga tctcggtaaa aaagaaagga gttaagaaga
     1861 aatgatttta cccgataagt attatcaagt cattaaatgg acagttttaa cagtattgcc
     1921 agctgcatct gtattagttg caacactagg caaagcgtat ggatggaatg gaacagatat
     1981 gacagtactc actatcaatg cagtagcaac atttttaggc gttatcactg gcgtgtcggc
     2041 ttataatttg aaaaaatagg aggaaacaaa tgaaaaagaa aattactatt actgcgatga
     2101 gcctattaac ggctcttttt ttattgccaa ttaatgggtt tgcctatacg attaacaatg
     2161 aatttaattt aggcccaaac gaaggtagct cacaagtagc aaataatcag tacattttac
     2221 tgcatgaaac ggctaatgaa acagcaacag gacgcaatga agcgcagtat atgcaacgtt
     2281 catggactag cgcttatact gcttatattg tgggagacgg cggaattgtt tatcaagtcg
     2341 gtcaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgcaaat agtcctgtgc
     2401 agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac aaggcatacg
     2461 ttgaattagc tagagattca gcaatgaaat atggtattcc acttacacta gacacaccgt
     2521 ataatcaacc agggatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata
     2581 cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta gcctatgatt
     2641 tggctcatgg atttaccgat gaaaatccga caacttcaga tgataaacca gtcattgatc
     2701 caactcgagc aggtgctgca aatcctaccc tgacagatgg aacaaattac gcccacattg
     2761 atcagttcgg agaaatcgaa aacgcaaact tacatgtggc tggttggcac atcgctaact
     2821 ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta gctcgagtaa
     2881 aagctgatgg aatatataga ccagatgtaa atcaagctta taatacttta ggaaatgttg
     2941 gctatcatgt atcttttaac atgcgcaact tccctaataa gaaagtctat gtaatgatgc
     3001 gggcaacgaa tgatccagaa gggaacacta aaggcggagc acaagatttt catgataaac
     3061 gctggtattt aaatattccg caacgataaa aatagcccct cgtttttgag gggaagtaca
     3121 taatgcaaat ttgtccataa cttattgatt atcttgtaaa aatgcggtaa tttaatagtt
     3181 agtgagaaga ggtgcttaat tatagttaaa aaagaggaaa tagaagcagc atgtaaccaa
     3241 gcaaatgtta ggtttattgg agaagcttta tctggatatc ctaagtataa atacttacac
     3301 aactggttac aaagtaaaag tttttatctt aataaagaaa gatgcatgcc taataaaaat
     3361 tatagggttt ataaaagagg aactattgta tatgttgatt ttggggtgaa cgtgggttat
     3421 gagttatctg gtaatcattt tgctattgtt ttaaataata aagataattc gaaaaatggt
     3481 gttgtatgtg tagtaccaat ctcttcaaaa aagaaaagta attatgtatc tgtaggaaaa
     3541 atattagaag ttgctagtat taaacaattt ataagccaag ctgataaatt aaaagagaaa
     3601 cttaggataa ttattttact ttcattaaat agaggcatca ttgatgaaag cgatttgaat
     3661 agttttatta aagatattga agctaaaggt gaaaagcttt cagtggaaga agtagaaaaa
     3721 cgagctgtaa aacataattt ggtttgcgag acaagggaac aagtaattaa agaaataaaa
     3781 tcattatctg aagatatggt aaaatatcag aaggtgttta attgctacaa gaaatataca
     3841 caagaatcct atgtaatgcc acttaatatc caaacgatta gtaaaaatag aattagaaga
     3901 attaacaagt ttgatccttc tggaaatatg aaggcacctg gaaatgtcct caatgaagta
     3961 gatgaaagtt taaaaaaata ttttacaaag taaacgatat ttttgttgac atttttctgt
     4021 tcgttagtta ccatgtagtt atagaaggac gtaagcgcct atttttaatg tacacatcgg
     4081 gacgtatgcg cccacataga aacatagttg agagacatct atatggtgtc tcttttttta
     4141 ttaatatgca aaaaagtcta gttttttcaa taatatttat gtaataataa attagccacc
     4201 acaacaaaga atgaaaccca ttattatcta gtctatgtcc attctttttg tttgcagtag
     4261 ttgtgatggc tttccgtact cttagctcag ttggttagag cagacggctc ataaccgtcc
     4321 ggtcgtaggc tcgagtccta cagggtacat actctaagtg atttaaattg cgaataaaat
     4381 ataaaaatga ctcccctttt gactccccca agcagtatat ggatgtctct aaaagttgtt
     4441 tttttagata ataaaaagct gataataagc gaaaaacact taaaatcagc tttaaaccct
     4501 attctcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc tgtaccttcc
     4561 ttatatcaac gattagaggt tgtgaagaag ctgtcctgca tcaagtaata agaacggcca
     4621 aacaaaaata gcttttccta ttttttcgtt tgattgggct tattaccgca gatgcaagct
     4681 tttgaacacc gtttgttcgg aataaggggc tgtgacaaga cttttgtcac agccccttat
     4741 tgttgtactt ttaacctaca atattttttg attccccctg agtactattt tttataaatg
     4801 ctagtaaatc aatcttcttt ggcctttttt tgataaaaaa aatactagat gtaagataaa
     4861 agtgtaaaaa cgatttgttt taggagggga aacgatgtgt accgcaatca cttatgcaac
     4921 gaaagaccat tattttggaa ggaattttga ttatgagatg tcttataatg aagtggtcac
     4981 tattactcca agaaattatc gtttcgattt tagaaaggta aaaaatttag ataaacatta
     5041 tgcaatgata ggaatagcag ctggggtatc caactatcca ctctattatg aggctacaaa
     5101 tgaaaaaggg ttgagtatgg caggactgaa ttttcctggc aatgctgatt ataaagaatt
     5161 acaagaagga aaagataacg ttgcaccatt tgagtttatt ccatggatac tagggcaatg
     5221 ctcaaccata gacgaagcta aagaattatt ggctactatc aatctagtca atatcgattt
     5281 tagtgaaaaa ctacccttgt cacctttaca ctggttatta gctgataaag aaaaatcgat
     5341 agtaattgaa agtatgaaag atggacttca tttatatgat aatcctgtcg gtgtgttgac
     5401 aaataatccg ccatttgatt atcaattatt taatctgaac aattatcgct cgctatcaaa
     5461 tgg
//
LOCUS       DASHXG010000105         5309 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.113, whole genome shotgun sequence.
ACCESSION   DASHXG010000105 DASHXG010000000
VERSION     DASHXG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.113"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(71..1219)
                     /gene="nagA"
                     /locus_tag="U2R59_002703"
     CDS             complement(71..1219)
                     /gene="nagA"
                     /locus_tag="U2R59_002703"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEM8967033.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1295..2131)
                     /locus_tag="U2R59_002704"
     CDS             complement(1295..2131)
                     /locus_tag="U2R59_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967034.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2315..3532)
                     /locus_tag="U2R59_002705"
     CDS             complement(2315..3532)
                     /locus_tag="U2R59_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8967035.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3681..3860)
                     /locus_tag="U2R59_002706"
     CDS             complement(3681..3860)
                     /locus_tag="U2R59_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967036.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3915..3998
                     /locus_tag="U2R59_002707"
     tRNA            3915..3998
                     /locus_tag="U2R59_002707"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3949..3951,aa:Leu,seq:gag)
     gene            complement(4238..4816)
                     /locus_tag="U2R59_002708"
     CDS             complement(4238..4816)
                     /locus_tag="U2R59_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967037.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4822..5205)
                     /locus_tag="U2R59_002709"
                     /pseudo
     CDS             complement(4822..5205)
                     /locus_tag="U2R59_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1736 t
ORIGIN      
        1 ttactagaac acaaaaaaaa ccttaaaacc aaacttaaga agtttagttt taaggttaac
       61 ttaaattata ttatgcgtgg aaacgttcca cgccatctag ataagttgct tccaatgtca
      121 tatcagggtt caatacgata aagtctgcat cgcgtccttg agcgattttt ccacatgtat
      181 catcgatttt acagctgatt gctggaatca gactagccat catgactgct tgttctggtg
      241 ttgctaatcc ccagtctaca acatttttaa ttgcttcttt caatttcaat atacttccag
      301 ctaagttgcc agattctaga cgtgctgttc cttcttttac tactactgga aattcgccta
      361 aattgtaatt tccatcaggc atcccaccgg ccatcataca gtctgtaatt aatgcgacat
      421 gatcatgtcc tgctttttcc attaggattc ccgcagcatt tggatgtaca tgatggccat
      481 cacaaatcaa ttcagaaaag acatgttcta aagataataa cgcacccacc atacctggtt
      541 cgcgatgatt caatccacgc ataccattga aagcatggac aaatacactt gcgcctgctt
      601 caacagcttt ttgcgcttct tctagtgtag cattactgtg tcctagagaa acaactactc
      661 cttcttcagt cacttgtttg acaaactctt ctacaccttg acgttccggt gctaaagcaa
      721 tttttttgat taaaccacct gaagcttctt gccattcatg gaaagtatcc aaatcaggat
      781 ccccgaaata acttgggttt tgtgcccctt tgtgttcttc tgtgaagaaa ggaccttcaa
      841 aatagattcc tttgatttta gctcctggtg cttcctgata cattttgccg attgtctcag
      901 ctacatcttt taaacgttct ttgcttgacg tcaatgttgt tggtaaaaat gaagtcactc
      961 cacaagataa cagaccttca gacatcactt tgatgccttc tgcatcatta tccattacat
     1021 catgattcat atagccgtga atatgtgtat ctaccaaacc aggagcaatc catttgccgc
     1081 tttggtcaat gatgttgact tctccctcag gtagttcttt ggtgtattca ccaaaaagtc
     1141 catcggtaat ttcaagatag cctgcatgtt tgacacctga cgctaaaaag aatttgtcag
     1201 catagataaa agttctcatt ctattctctc cctttgtttt tctacctcta aagtactctt
     1261 atttagagaa gaagtcaaga atggtctaca ccatttacaa attttttgaa atttgtttca
     1321 cagcttgtgc taagccttca tagaatgctg ctctttctgg ttcttcttta cgcttgtata
     1381 ttaagctttt aagcacaaat aaatcattga ggtaatagta gctattcttc tcttgagccc
     1441 aatagattcc ttgattcacc tgttctaacg cttcgtcgat ttcattttga tggaataaga
     1501 aatttccata attataaaaa atttgcgaaa attcactttt tgatcgttca tcagctgatt
     1561 gatgcagcag ttggatgctt cgactcaaat agtagcgtgc ttcagccgtt tttcctgcca
     1621 caccatatat ttttccgata caactaatca gttgtatttc tgtgtcagaa acatggattc
     1681 tttctttttg gctagagtag cttaatgctt ctttcaaata ataaagggac tgagagatat
     1741 tttgacgcaa cgtgaattcg caaacaccga gataataata atagcgttga aagtcagttg
     1801 cttgatacag attttcagaa atatcagaag attttagtac ttgttctaac ttccgataat
     1861 cacgtttttg gaaacaacta tccaacagtt caaataattt atcgtttgtc cgagtagttt
     1921 ttcgagagag attcatcaca tgatcaatcg ttacccctag ccgttgacaa atctgcatca
     1981 tcaccaatac attcggcagt tcctcattat tttcgatccg acttaataca ctttgtgaac
     2041 aaatatcatg cgaaagcatt ttttgcgtca ttttttgttc ttttcgaatc tctttaatga
     2101 tcgttccaaa ggactcgatt aacgtttcca taagtatcct ccccaaaata tgcgtattcg
     2161 cattctattc gtattttact ttaggaagtc gcaaacttca agaaaagact tgcaactaaa
     2221 taatatactt tagttattta agaaaactcc actagaaaga gagcctcagt gtgtttgtct
     2281 gtggccctcc tactgaaaaa tttggttttt aaaatcattt ttggcgatag gttgctagga
     2341 attctctcat tttcttagct gtttgtttca aatcatccat tttaggaaga taaacgattc
     2401 gaaaatgatc tggctggttc caattaaatc caccaccatg tacaagtaga atatgatgtt
     2461 catgtaaaaa gtccaaaacg aatttttcat catccaaaat attgaatcgc tttgtatcaa
     2521 tttttgggaa tatataaaaa gcagcttttg gttttacggc tgaaagacca ggaatatcat
     2581 tgattgcatt atagatatat tctctttgtt catagatcct tccgcctggc aggagcagct
     2641 catcgacact ttgataaccg cctagcgcgg tttggataat ttgctgagac aatacattgg
     2701 aacacaaacg catggaggac aacatattca gcccttctat atagcctttg acgtgtgact
     2761 tatctccact taggaccatc cagcctactc gaaatcctgc tacacgatga gatttggata
     2821 gaccgttcag cgtaacaacg aacaaatcag gcgctaatgt agcaatcgga atatgttcta
     2881 gaccatccat cactaagcga tcatagattt cgtcggaata aataatcagg ttattttgtc
     2941 gagctacttc aacgatttct tctaataatt cttttggata aagtgcccca gtaggattat
     3001 taggattaat gataacaata gcttttgtcc gactcgttat ttttgatttg atatcatcaa
     3061 tatcaggata ccattctgcc tcttcatcgc aaatataatg aacaggtgtg cctccagcta
     3121 atgcaataga agccgtccac aacggatagt ccggcattgg aaccagtact tcatctccat
     3181 tgtccagcaa cccctgcata cacatcgtga tcaattcgct cactccgttg ccggtgtaga
     3241 tatcattgat cgtcacattc ggaaaatgtt tcagttggca atattgctca attgcttttc
     3301 tagcagaaaa gatccccttg gaatctgagt agccttctga gtcacgggca ttcatgatca
     3361 aatcacgaat gacttcgttt ggtgcttcaa atccaaaagg tgcgggattt cccgtgttca
     3421 attttaaaat actaatgccc tcttcttgca tccgctccgc ttcttctaga acgggaccgc
     3481 gaacatcgta actgacacct tctaatttgt tggatttttc aaattctctc atcacttagc
     3541 caatccctca tttcaaaaag ttagaacttt ccaaattttt tgttatttac tatttcaata
     3601 tcatactcca tcctagaaaa ttttgccact tatttaggaa aaacgtaagt attaaaaaaa
     3661 cacaaacaag cgttgagaac ttaattgtca tgatagtcat tccatagatt cgctgcccaa
     3721 tccattgcaa ttccacaaat gattcctagc ataaaaccaa gcaaaaaacg tccgaatgca
     3781 agtccaatca atacacctaa gatcattccc agtcctgaaa attctccgtc atatttctcc
     3841 atcttaataa gtcctcccat ttttgagctt gacaactatg taaaacctcg ctatcattag
     3901 tgtgttatta ttacgcagat gtgttggaat tggcagacaa gcatgattga gggtcatgtg
     3961 agcgttagct cgtgtgggtt cgagtcccat catctgcact acaactcgtg aagttaattt
     4021 tgcttcacga gtttttttgt ttgaacgttt ctttatgcca ttatatacat atcactgtat
     4081 cctttacaaa aagaacgtac aatcatgtaa acagcctgag gtgagtatat gaaggtcgga
     4141 aacaagctac tcgtagaaac ttgcaagtgt taaaacaatt aatcgaaaaa cgagtaaaat
     4201 ccctcaccta atactaaagc gagggatttt ttgtatatta tctgtttatc accgttatta
     4261 taaaggtaca aataccaagc acggttaatc caaattgcat aaattcattt ttttgtacac
     4321 tcatgctttt cattagctct ttaactgcca ttagtactaa gatggcgata acaacataaa
     4381 gtatatagta cgtccgcatt ccggaagccc atactgtggg agaaaatccc ataattaacc
     4441 ttgaacaaaa tcccattatc atcaaaataa ctaaaaaaat agaagttttc ttattgtcaa
     4501 aacttaaata aattccaaca attaaacata gtaataatgc caagactact aaagtagcta
     4561 tccaagtacc tggataaaaa agtgacagtt tcgttcctaa ctctgtaaag agattattca
     4621 ggttactact actccaaatc attgcccttt tatttccatt gacgtaagta aagctttgac
     4681 ccattgtatt accaaaataa ataatcaggt ttaagaaaaa cggtaatgca gtcaatatac
     4741 gcacataata gttttgacat ttcctatatg ttagaaggaa aattaagaaa aatagcaata
     4801 aaaataagat attcatgtct aaaaaaacgg ctttccaaat gatgaaatac ctaaatctaa
     4861 cttattaaga aagttgaaat ttttatattc aggaaaccat ttattaattt catgtgcagc
     4921 acgtaatgca ttccctggag ttgtcaaaga gaaaattaat tctgctaagc ttattattga
     4981 aaatactgat aacttataat tatatcgtcc attgacaatc aaatataaac taactatact
     5041 tgttagaaca aaaaaacagg cgttgacttg ttcttgatta gttaaaaata tcaataaagg
     5101 aatacttacc caatatattt ttctatttat ttcttctcct cttaagagtt gaaaaaacgg
     5161 ataaaaagtt agtaaactaa atgctactgg ccactgatag ttcaaggtgg ttgctctcca
     5221 accggtttcc cccattactg tcaatggtat taaacagtat atagagcaaa ccaataataa
     5281 atttttaaca tttattttct caaaaacat
//
LOCUS       DASHXG010000106         5256 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.114, whole genome shotgun sequence.
ACCESSION   DASHXG010000106 DASHXG010000000
VERSION     DASHXG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.114"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..371)
                     /locus_tag="U2R59_002710"
     CDS             complement(<1..371)
                     /locus_tag="U2R59_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967038.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSISTLYRRFKTGEFNVLHLP"
     gene            1014..1577
                     /locus_tag="U2R59_002711"
     CDS             1014..1577
                     /locus_tag="U2R59_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967039.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1856..2143)
                     /locus_tag="U2R59_002712"
     CDS             complement(1856..2143)
                     /locus_tag="U2R59_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8967040.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(2133..2462)
                     /locus_tag="U2R59_002713"
     CDS             complement(2133..2462)
                     /locus_tag="U2R59_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8967041.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2767..3096
                     /locus_tag="U2R59_002714"
     CDS             2767..3096
                     /locus_tag="U2R59_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967042.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(3383..3868)
                     /gene="vanZ"
                     /locus_tag="U2R59_002715"
     CDS             complement(3383..3868)
                     /gene="vanZ"
                     /locus_tag="U2R59_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEM8967043.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(4021..4932)
                     /locus_tag="U2R59_002716"
     CDS             complement(4021..4932)
                     /locus_tag="U2R59_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HEM8967044.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         1690 a          913 c          815 g         1838 t
ORIGIN      
        1 atcggtaaat gtaaaacatt gaattctccc gtcttaaacc ggcgatagag ggtacttatt
       61 gaacaagaga aggttcgctc tgcacggcca ataatgacgt ctggggtcca accttcagtt
      121 gatctttttt caatgtattc tttttcctca gcaggaaaaa tgatttcggt tctcccacaa
      181 cgtcgcttat tttctttgta ttgttcaaag tattcaagtg ctgttccacc acatttgaga
      241 aagttataga cattgtaaat tgtttggcgt ccacgtttaa gctgcttcgc aacgatagca
      301 accggagttt cttgatgaaa atatgcttct atcattacaa gctcgtttgg tgtaagatgg
      361 gtataagtca tttatgttca ctctccttgt atgctttagc gggtattaca atttgagtgt
      421 aacataaatg gcttttttat ttgtctcgct taattataca aacggcgaag ttaaaacttt
      481 tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag cattcaaata
      541 gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta ataaagttat
      601 tcttttttta tccaatacat tcagctcaat tccttataat attctattcc ttagtatctc
      661 aacattattt actttataaa acgaataaat tttgtagttc taattcaaat attgcatgtt
      721 atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat taactttagg
      781 atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt tttgtttatt
      841 tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat gacctctttt
      901 attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat gtatctataa
      961 ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa agcatgagtg
     1021 gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat cgtcaattag
     1081 acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg ggaaccaaag
     1141 cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat acggtaattg
     1201 tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt gttacctatt
     1261 ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc agcacgcctc
     1321 acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt gatttaattg
     1381 ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa ggtggccgtc
     1441 cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt caggtttata
     1501 gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac cgctacttaa
     1561 aagacaatag ggaataatct attttaatct ttaggaatct ataatattta tgggagaatt
     1621 agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt aagccctctt
     1681 tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt aattttttct
     1741 atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa ctctcagctg
     1801 ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg ggttcttacc
     1861 taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag ataggtatca
     1921 ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac ttgaatccaa
     1981 tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga cgaactgcta
     2041 tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt aattttttta
     2101 gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc tgccaactcc
     2161 tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt aaatgcagaa
     2221 gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct ataaccttct
     2281 gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt aggctctaca
     2341 aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc attgggcaca
     2401 tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt ttttgtaatc
     2461 atattatttc ctccattatt ttacatttcg taattactta gtaattacat tgtacgctat
     2521 ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag gagttttatt
     2581 tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa aacgcacttg
     2641 caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa ttaaggtaga
     2701 ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga atgtgaggtg
     2761 agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt aaatggaata
     2821 aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa atgtttcagc
     2881 gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat gtgcgtctgt
     2941 gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt acgtttttta
     3001 aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta ctctttagcg
     3061 aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat ctatctatga
     3121 aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag gaaatttatt
     3181 aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt actatagtgt
     3241 taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac gggcgagttt
     3301 ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg tatgaaagat
     3361 cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta cggtaaacga
     3421 gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat tttttttgat
     3481 tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca acagtatttg
     3541 taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt atttcaaaag
     3601 taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct ttaaaattga
     3661 cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc tctctgaaat
     3721 tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta aatactgata
     3781 aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa tataaagcta
     3841 gcaatcctct agataatatt tttcccaata taatttcctc taattctttt gtttaagttg
     3901 tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag ctaacgttac
     3961 cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat tccgccatcc
     4021 ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta caccgtctat
     4081 attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg tatttttagt
     4141 aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa tggttttttc
     4201 ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca taatcgcact
     4261 atgtggtaaa ccaacatagc gaatatgcca tggttcatat tgaattcctg ttaactctgt
     4321 tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt ctatccactt
     4381 tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg ataaacctga
     4441 attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt ggtaaagcac
     4501 actttgctca tcaaagtctc gatagccact attaataata aaatgactaa cgccaccctt
     4561 tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca tataaatatt
     4621 actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat tcacgatatc
     4681 tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca gatttccttg
     4741 ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc cactattttc
     4801 taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct gagaaaacag
     4861 tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca ataaaaaaaa
     4921 caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga aatatttcta
     4981 gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc cccgtaaatt
     5041 acagtcaatt atttcgccct actggattta ctattatcac caatgtagat gaattttcat
     5101 aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg ggcggtgtga
     5161 aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca gcgcacgcag
     5221 ataatgaccg caatatcgct ctgccttaca tcttca
//
LOCUS       DASHXG010000107         5024 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.115, whole genome shotgun sequence.
ACCESSION   DASHXG010000107 DASHXG010000000
VERSION     DASHXG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.115"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            282..521
                     /locus_tag="U2R59_002717"
     CDS             282..521
                     /locus_tag="U2R59_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967045.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="U2R59_002718"
     CDS             complement(883..1143)
                     /locus_tag="U2R59_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967046.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="U2R59_002719"
     CDS             complement(1328..1825)
                     /locus_tag="U2R59_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEM8967047.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="U2R59_002720"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="U2R59_002720"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEM8967048.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="U2R59_002721"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="U2R59_002721"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HEM8967049.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5014)
                     /locus_tag="U2R59_002722"
     CDS             complement(4547..5014)
                     /locus_tag="U2R59_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967050.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1042 c          771 g         1682 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gcaa
//
LOCUS       DASHXG010000108         4932 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.117, whole genome shotgun sequence.
ACCESSION   DASHXG010000108 DASHXG010000000
VERSION     DASHXG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.117"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            84..971
                     /locus_tag="U2R59_002723"
     CDS             84..971
                     /locus_tag="U2R59_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEM8967051.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1111..2037
                     /gene="cysK"
                     /locus_tag="U2R59_002724"
     CDS             1111..2037
                     /gene="cysK"
                     /locus_tag="U2R59_002724"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEM8967052.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2273..2719
                     /locus_tag="U2R59_002725"
     CDS             2273..2719
                     /locus_tag="U2R59_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HEM8967053.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2992..4344
                     /locus_tag="U2R59_002726"
     CDS             2992..4344
                     /locus_tag="U2R59_002726"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HEM8967054.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4515..4802
                     /locus_tag="U2R59_002727"
     CDS             4515..4802
                     /locus_tag="U2R59_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967055.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1694 a          813 c         1030 g         1395 t
ORIGIN      
        1 attaaaagta taatttaatt aattaagttt gttttaagaa gagaactttt tattaagttt
       61 ttttattttg aggaggaatt tgaatgcaag agctgaagac ccgcagtgcc cggcaccata
      121 gacctaaaag aaaaatggtg atcaataaaa aagcgattgc tcctttaatt ggaacgagtc
      181 ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca gatgaacaag
      241 gatctcaaac agtcgctgat cctcaagcgt ttatcgatca aatcggctgg tctgcgtcag
      301 aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg ttgttggaaa
      361 gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc ggtgtgaaag
      421 gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaaac ggacaatggg
      481 taacgatgaa tgagccattc cgaaaatatt cttcttattg ggaatccttc caagaccatg
      541 cgaatgttct tcgttcaacc agtttttcca cgggcgatta tcattatgct ggcgtgtgga
      601 aaagcaatac aacaagtttt tatgatgcaa cagcgtactt gacaggtcgt tatgctaccg
      661 atccaaatta tggggccaaa ttgaactcat tgattaatac ttataattta acccgttttg
      721 atacgccatc aacaggttcg gctacaacaa ccacaagtac aacaacaacg actactacga
      781 cgacttcaac gtcatcatct tcaacaacag atgtaaatac aaataatggt cagacatata
      841 cagtcgtgtc aggtgatacg ctatgggata ttgcacaaaa atttggcatg tctgttgatg
      901 atctaatggc gaaaaatggc atgtctatgt ccagttattc tttattagtt ggtcaagaac
      961 taaacgtttg atttagataa aaaggcaaag aaattaccat atatggtata tctttgtctt
     1021 ttttttgcta gtcaaagacg aatcactcgc cataaatgaa cagattgtat tatgataagt
     1081 aagaagagca aagacaagga ggaattgaag atgacagcta tctataactc agtcaccgaa
     1141 ttgattggca aaacgccaat cgtcaaatta aataaaatcg taccagaaga ttcagcagat
     1201 gtttttgtaa agcttgagtt ttttaatcca ggaggaagtg taaaagatcg tattgcttta
     1261 agtatgatag aaaaagcaga acacgatggt ctactgaaac caggtgatac tatcattgaa
     1321 cctacttctg gaaatacagg aatcggattg tcgatggtag gagttgcaaa aggatataaa
     1381 gtaatcatcg tgatgcctga gacgatgagt atcgaaagac gtttattgat gaaagggtac
     1441 ggcgcagagt tgattttgac tcctggtgcg gatggtattt ctggatcaat cagagaagca
     1501 gaacgtttgg caaaagaaaa cggctacttt ttaccattac aatttgaaaa tgaagcaaat
     1561 cctcttgtgc atgagaagac gactggtcct gagatacatc aagcatttgg agtaaatggc
     1621 ttggacgcgt ttgttgcagg tatcggtaca ggaggaacga tcactggcgc tggccgagaa
     1681 ttaaaacgtg tgtatccgaa aatcgaatta atcggggtag aaccagcaga atctgctatt
     1741 ttagaaggga aagaagcggg acctcacaaa atccaaggaa tcggtacagg ttttgttcct
     1801 aaaacactgg atacttctgt gtatgataaa gtcctttcta ttagtggaga cgaagcgatg
     1861 gaaacagcta gagaagttgg gcgaaaagaa gggattttag taggcatctc atctggcgct
     1921 gcaattgctg ccgcgctaaa agtcgcaaaa gaattaggaa aaggcaagaa ggtattagct
     1981 gtggttcccg acaatggtga acgttattta tctacagccc tttaccaaga gatataaggc
     2041 acttggtttt tctccagata ggtttatgta aaaaactttt aaagatgaaa agaacacaca
     2101 aaaatttatg atgagaaaaa ttatttgaat agagacgtag aatagtgaac gcgactgttt
     2161 tacgtctttt ttcattaaaa tacaataaaa ttgaattttc ttttcatgtt aagtggattt
     2221 taaaatgtaa aaatagtatg ataagacgag aataacaacg tggggtgttt acatggaaaa
     2281 taagttagtc gaagaggtta tcgaaaagtt aaaaaaagag aacattcgaa tcacacctca
     2341 acggtacgcg gttttagaat atttgattga acatcattcc catccaacgg ctgatgagat
     2401 ttataaagca cttgaacatc ggtttccaaa tatgagtgtt gcgactgttt acaataacct
     2461 tcgcttattt acttcgattg gatttgttca agaaatgaag tacggcgatg cttctagccg
     2521 atttgatttc agttcaaagc gtcattatca tgtaatttgt gaaaactgcg gtaagattgt
     2581 tgattttcat tacccagggc ttgaagatat agaaatggct gcaagcagac tgactgattt
     2641 tgagattaat gaacatcggt tggaattgta tggactctgt ccggattgta aagagtcagc
     2701 aaaaaaggcg caaatgtaaa aacagtttct acaagtgtta tacctaaaaa aagctagctg
     2761 tgtaaaaaaa acgctagctt ttttattttt ttgtctttta ttcacaatct tagatataaa
     2821 agtgaatatt attaaaataa gaatcttgta gatattgggt tcttatgctt gaaaaggaat
     2881 gaaactacaa acaaaccttt gtgaattcac aagcattaaa ctgttgtatc cgttttattt
     2941 ctgttatagt agttttgtcg aaggacaaaa tgttaatcgg agggaccata aatgaaagta
     3001 gtagtaattg gctgtactca tgcaggtact gcagctgtaa aaagtatttt aaaaaatcat
     3061 ccagaagcag aagtgacagt atatgaaaga aatgacaata tttctttctt atcttgcggt
     3121 atcgcacttt atgtcggcgg agtagtaaag gacccagcag gcttgttcta ctcaaatcct
     3181 gaagaattat cttcattagg agcaacagtt aaaatggaac acgatgtaac agacgtcgat
     3241 acagaaaata aaacagtaac ggcaaaagat ctgaaaacag gagaaacaga aacggtttct
     3301 tatgataaat tagtgatgac aactggttca tggcctatta tcccaccgat tagtggaatc
     3361 gatgcgaaaa atgtactcct atgcaaaaac tacaatcaag caaatgaaat tattgcacaa
     3421 gcgaaagaag caaaacgtgt agtaattgtt ggtggtggat atatcggtat tgaattagta
     3481 gaagcttttg tcgaatctgg aaaacaagtg acattgattg atggattaga tcgcatcttg
     3541 aataaatatc tagataaacc attcacagat atcttagaaa aagaattgac agaccgcggt
     3601 gttactcttg cgctaggcga aaatgttact gaatttatca cagatgaaga aggaaaagtg
     3661 aaacaagtag ctacaccaac agatacattt gatacagata tggtcatttt atgtgtgggc
     3721 ttccgtccaa atacaaaact gatcgaagga aaagtagata cactgccaaa cggggcaatc
     3781 aaagtgaatg aatacatgca gacaagtaat ccagacattt ttgcagctgg agactctgca
     3841 gtagtcaact acaatccaag tggcacgcaa aactatattc ctttggcaac aaatgccgtt
     3901 cgtcaaggtt tgcttgtggg aaataacttg acagatcata aaatggcgta tcgtggtact
     3961 caaggaactt caggacttta cctatttggc tggacgatcg gttcgacagg tgtgaccaaa
     4021 gaaagcgcaa ctttgaacga tctagaagtc caagcgactg tatttgaaga taattatcgt
     4081 ccagagttca tgccaactac tgaaaaagta atgatggagc tagtctatga aaaaggaacg
     4141 aatcgtatcg taggtgctca gttcatgtcc aaatacgaca ttacacaatc agcaaatacc
     4201 atgtctttag ctgttcaaaa taaaatgact gtagaagatc tcgcactttc agatttcttc
     4261 ttccaaccac attttgaccg cccatggaat tacttgaacc tacttgcaca agcagcgcta
     4321 ggcgaaatcg aaactgcaca ataaagaaaa agggttgtga cacaattttg tcacgaccct
     4381 ctgtcttttt ttgtgaaaag tacaattagt tgtctttctt cgaatttttt gtcacaataa
     4441 gcagcaaaga taaagctgtt acataaaaga acaagcagct ttatttgatt ttgaaaagaa
     4501 aggtgagaaa gaagatgaat aaagaatatt ttgtccaaca agatgcattt ttagaagatt
     4561 ataaaagtgc ttcgaagaaa ttaacgatca atattgatga gttggcagat caagtactct
     4621 ctcagttgaa tgaaacgcaa gaggaatatt acacgatgcc agcaaatgac gccaaagata
     4681 atgtttctca tcgttttcct ttcagtagac gcatctactc agatgaaaat gacggcacat
     4741 tgaatacaga gtacacatat gaaggtcagc catatgtgct agaaactgat gatgatcttt
     4801 aaagacagtt tttgaaaagg ccgctcatcc ttaagtgatg acaaaaaatc atcacaatta
     4861 ccgatgactg tctctttact atcttttaat cagaaaaagg ggttatgaca agctttgtca
     4921 accccttttt tt
//
LOCUS       DASHXG010000109         4810 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.118, whole genome shotgun sequence.
ACCESSION   DASHXG010000109 DASHXG010000000
VERSION     DASHXG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.118"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(92..1177)
                     /gene="xerS"
                     /locus_tag="U2R59_002728"
     CDS             complement(92..1177)
                     /gene="xerS"
                     /locus_tag="U2R59_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEM8967056.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3253..3771)
                     /locus_tag="U2R59_002729"
     CDS             complement(3253..3771)
                     /locus_tag="U2R59_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEM8967057.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1581 a          786 c          729 g         1714 t
ORIGIN      
        1 atataaaaat gataatgaag cttgccttta aagttgggct tttatctaat tttagagaca
       61 ggcttcatta ttatactatt ttttactaca tttacaaagc gttcaaagca tcaattgtag
      121 ctgcattgtc tatatgagta tataaagttg ttgtatttgt acttgtatgt cccaattgtt
      181 gggcagttaa taccaatgaa tttgtctgtt gatagagtct agtagccaaa gtatgacgta
      241 atttatgtgg actgacttgg actctgaatc cttttgaata ttttgctacc atccgttcga
      301 ttgcaatacc ggatatacgc ttggcttctc cttgataaat tgctagaaat aaagcttttt
      361 cgttttctgt tactttgtat cgttctttcc gaatagctag ataattagct aaatattcca
      421 ttgcaaatgc tgctatattt actgcgtctc tcttatttcc ttttctagtt actaccacat
      481 tattcttttc taaagatagg tcctctaaat taatatttac aacctcggag agtcttaatc
      541 cagatcctaa aatcaatgca ttgatcgcca ggtctctttc tacatctcgt tgataataga
      601 tcaaagctcg tttgctcaaa gtttttttat attcattggc aatataatct agataatttt
      661 gtgtatcttc gtctagaaat aattttttct cgattgcgtt tgcacgggca gctaacgtag
      721 ttttatctgt gatagttgct acttgatcca taggattatt ttctaagtat ggttttccta
      781 aaggattatt ggaacttttc gaaagatatt taaatagaac ctttaatgct gtgatatttc
      841 tattgatagt agaagtagat agacctaagt tattattatc tttgagctta gtttttgttg
      901 tctctttttt tacattttcc tttgtgcgac gtttcaaatg agatttgtac aagtttagat
      961 cataggcagt taactgtctt atcgaggtga ttgaagtatc gggaacgata gactcactca
     1021 gaagccattc ataaaagagc ttataatttt ttagatattc taaagtagtt cgaggtgatt
     1081 gatctttatc ctcacgatct tgaacaaaat cttttatata atcgggcata tgaagtatga
     1141 ttgtatctat tttttgatat atttctgtat ttttcatgtt attcatcctt tcgataagta
     1201 ggggagagga gtatctctat aattggacta taccaattat agagtgtttt gtcaattggt
     1261 atactctgaa atttattaat ttatttcaaa aaagcagata aataggtata gatttaataa
     1321 tttaaaataa atggtataca tgaataggaa aggaaacaga aggaggcaat cttaattttt
     1381 taaattgtct aaattatata gaaagaacaa tctttctata taattagaca taagagagac
     1441 tacggttgat ttgatattaa caagcgtata tgaatgtata tacaaataaa aaaggggagg
     1501 gagaagttaa agaaaattca gagaagtggg gcactcagta gtattaacaa tttaaaagga
     1561 atttcttaaa gaaaatgggt tgcatcctgg agatacaatt tttttagata aagaaaaaat
     1621 tcaagcaaca attcaaaaaa atcttaactg ctgagattga tgtagcaata tctcaatcat
     1681 caacaaagta cgatcctgcc tttcaaaagc ttattgataa atgtttattc attataaaaa
     1741 taaaagaaaa atttatgtca gcttttttca tcaaagtggt aatgataatt cgtctattaa
     1801 ttgtattttt taggaaatat ggtataattg ttttaacgaa aaggtaattc atgatacacc
     1861 aaaaaccact agctggcggg ctagtggttt tcttttacgt tctattcaga ttaacgggta
     1921 ggcttactgt cttttttggc aataattttg caatcaagcc atttacagat gtaatgcgcg
     1981 gatacttctg ctaagattgc aaaaaacata tcgaaaaggt aattcataat acaacctcct
     2041 ccccttgcca taataggccg gggtagcaga cagcataaat attataccat aactgaaaat
     2101 ttcattttag tacatttcaa tatattgatg aaccagcaca ataaaacatg ccatgactaa
     2161 cagaaaaaaa cttattaaac cagatataac ttgtaaacat ccaactatat agaaaacgta
     2221 aattttctat atagttggat taagataacg actatttatt ttatcatatt tttactatac
     2281 cctatacttt tacttggtat atttatgaat aatcgcaaat ttacccctat actactagtt
     2341 tgtaagttag attaataaaa atactaaagt tatttgttct tttattaaat acacctacaa
     2401 cttataaatt gatggtattt agataacacg aaagaataaa aataacagct gatagtaaag
     2461 tttgttgacg attgctactc aatcgaaagt gagttagtgc gtatgaactt gcttctgaaa
     2521 acttatgaaa tgaaagacct tttacatctt gcagaaatcg ttactgggat taaactaagc
     2581 aataaaaact aatgttcccc tcattctttg aacttctact atttgattta tttattctga
     2641 taaatgacga tttcaccttc aggatcttca aatcccgtat agaatttatt taagatctct
     2701 tcagtatcag taataggata ggcgataggc cacataccct ttgatggtta gaataaactg
     2761 ctcaaaatct gtatcgtatg ttggctttag catattaaca aaggctatct ccaaattata
     2821 aaccataagc gttgaatcgt tcttaacaat ttcaattctt cctaacccaa agtcagaaga
     2881 tataattacc ggacttgcct tacccttcat gtgggttgtt gagattccat atttaaaggg
     2941 aattgtcggt actatcggcg gtctgaaaaa catcccaaaa ataaaaaaat ctttcccctg
     3001 ctagtctcct aagtcccttt gtagcggata tggcaccata atctcatttt atcgaagtga
     3061 gtcatggttt atctgttggc caaccaaaat tgatacaatc taacgatgca ccctctacgg
     3121 cattctaggg gagtgcactt gcattcaccc aataaaaacc ggcagttagc aaagaactta
     3181 tgtagtcgta tgttcttact gttaacatac aagaggtctc ctttccacaa ttgcttagca
     3241 gtaaacggga atttacaaag ctaatctctt ccattttctt atctttgttc taaaagtccc
     3301 aaatggagca actgtattta catgaataaa tttatatact tcccatacag ccgttttggt
     3361 tgcctcgtct gcccattttc ttttgtgtgc agtgaataga tcttcatcac tcattgaatc
     3421 aatcatcatg ttaatatcat caatattacg attgagaatt tcctctaatt ctttcaatgg
     3481 tagatgtgca taggtatttg taaaccactt atataactct cctaactgat tccatttaaa
     3541 ttgatcagaa ggcgttttaa cagataatcc atttctttca tcattttccc attttagaat
     3601 taaattcgtc caaccaactt gatatgctaa attttcagca ggtgttctat ccacttcctc
     3661 aactctttta tccttcaatt cttcaggaat agtttcaaat tctaaaatat atttagtata
     3721 agtcctattt atttcttttt ttaattcttc tttattttta tatgttctca ttatattacc
     3781 tccataaatt cctaattgtc tcctttaatt catctataat ttcatccacg atattttaat
     3841 ccgttctaca atgcatatct gatatgcatt gactgtctaa ctcatatgtg aatgatttat
     3901 aaaatatccc aacgtctcat ctaaagaaat gttgatcgtc agcaaggagc taaaaaatac
     3961 gaatatattt cttttgtagt aaaatcggac tggtttgcat atcattttct tcgtaaatat
     4021 caaaatcatg ttaactacta tcaattacta ataaaaacta ccactttaag cgttaagaac
     4081 tgttaagttt agttaagtga ggatagttca caaaatccat tgttaaactt cacgaaagtg
     4141 gtaaaactca aaatgcttta tataggatta cagcatcgct ctttcttcga ttgcgcgttg
     4201 ggtaaaaaat attatgaagt aaaaattgac gatgacacgt tccttacggc tcatcagatg
     4261 aaacagctac aaaaacgaaa tgatcaactc gaagaaaatt taattctaaa aaagcgattg
     4321 ccatattcac gcctcgctcg acgaactatt aaaggtcaag atttacctga agatcatcct
     4381 ttttaggaaa ttgaagcttt ttatgttgca caatgcattt ataatactac aatgatgttt
     4441 tcaccagata ttcttctagg gtgcggtgta atgaaacaga tacacttgca aaagaaaatt
     4501 caccgcgaat ttactaaaat tatgaataat tatgttaatc ttccgaaatt tttttccaaa
     4561 attaagggat caagctggtg ttatagattg tttaaggttg gcaaaaaaat aacttctttt
     4621 taaacaatta tagaaaaccg atactctgtt aagttggttg acacggtgtc gatttttatg
     4681 actttcttat tctgaaactt cactaacgga cagtacctaa aaagtctata gtatggacgt
     4741 ttacgagtac tattttatca aaaatgctgc tcatttcaac ttatatgttt tagtgaacta
     4801 cccccactta
//
LOCUS       DASHXG010000110         4783 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.119, whole genome shotgun sequence.
ACCESSION   DASHXG010000110 DASHXG010000000
VERSION     DASHXG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.119"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(522..878)
                     /locus_tag="U2R59_002730"
     CDS             complement(522..878)
                     /locus_tag="U2R59_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HEM8967058.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(892..1302)
                     /gene="spx"
                     /locus_tag="U2R59_002731"
     CDS             complement(892..1302)
                     /gene="spx"
                     /locus_tag="U2R59_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEM8967059.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            complement(1649..3835)
                     /locus_tag="U2R59_002732"
     CDS             complement(1649..3835)
                     /locus_tag="U2R59_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HEM8967060.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            4053..4736
                     /locus_tag="U2R59_002733"
     CDS             4053..4736
                     /locus_tag="U2R59_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEM8967061.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
BASE COUNT         1323 a          898 c          767 g         1795 t
ORIGIN      
        1 gagtgtttcc cgattcgttt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacaact cagttatctt atcatgtcat
      241 ttctaacatg tcaacaacta ttttatatgt tttttaaaat actattttat tgctttgcta
      301 cttaaaacaa cagaaatgaa tatatcatgt aaatttacac atgtcaatat atttttaact
      361 ctatatcccc acctagattt gaattttgac cacataaatt gagcatgtct ctatagtaga
      421 aaaataaagt caaaaaaaga acacataaca cgcttgatgc taagtgttcg actgttacaa
      481 ctgtatgaaa tgctcagtga cttgattaaa acagttaaag tctatttatt taagataagc
      541 tgttccatca actgctcatt gtatccaata aatagaactt catcgataat aatcaaagga
      601 cgtctgagga gattggtatg ttgtgtgcat aaaaaaatca gttgtttttt tcctacacag
      661 gaaaggtcaa tcgcaatgtt gtgaaaagcc tcagaccaag tcgcaaatag ctgttctgct
      721 tgcacttctt caaaactgca taattcttct gcttcttctg tacttagatc gcgttcttct
      781 aagtcaacaa attgataagg caattgatgg tgttctaacc attgtttcgc cttcagactt
      841 gttacacagt gcgctgatcc atagactttc acttccacga aggctccctc cctatgaatt
      901 taagatgtta ttgttttgta aatagatcag atttctggca acacatcgaa tttcacgagg
      961 gacaaatgac cggatctcat cttcattaaa tccgattagt attctttttt catcaatcaa
     1021 aataggtcgt ctcaataatg aaggatattc tttgaataag acgatcattt gctttaaagt
     1081 taattcgtta aaatctatgc ccagcttttc gtaaattttc gaccgagtgg aaataatatc
     1141 ttgaactcct ccttcagtcg ctgccaagat ctttttgatc tcactttctg ttaacggttc
     1201 ggcaaaaata ttcttctctt caaattcaag ttgatttgct tgcaaccatg ctcttgcttt
     1261 tctacaggaa gtacagctag gcgaagtata tacttttatc attttctcac tcatttttaa
     1321 ttataatcca attctacagt aatttctttt aaaataccaa ttattagcta ataatatata
     1381 aaaaaaaatc aaaataactg attatttacg tttgaataat gagaattttt ctatatattc
     1441 tctattttga taatagtatt ctcattttca aaataaataa gggaggtgtg acaaaattct
     1501 tgtcacacct cccttttccg aataaactgt gttccagaaa tagcttcttc gaaaataagc
     1561 tgaaatttca caaaaatttg agaagcaatt ttcgtacatt ccttcttctt tcttgaaact
     1621 gaccacttct gtcacaccct ctcttctatc actttccttt tttcacacga ctcccggttt
     1681 ctttgataaa tctcgatact ttcaattttc ttgaattttt catttgaggt acacatagat
     1741 acagacgatt tcttgctcta gtcatcgcaa cataaaatag tcttcgttct tcttctatcg
     1801 tcgtcactgg ttctgctttt atttcattaa agtcgattac tttcttttct gtcgctccgt
     1861 tataaggcaa acttccttcg ttacaaccaa tcaaaaagac atttcggtaa ctaagacctt
     1921 tacttttgtg aatgctctgg atacatagtg catcaagttt tccttgtctg taagcaatca
     1981 agcgggtttt taattcttta gctgtcgctt gggtttcttg cgataaggct tggagtcttc
     2041 tgaaagtagc atgctgcttt acttcttctc gtatccattc ttgatcactc tggtcgattt
     2101 ccttagctat acgtggcaga tgaagatagc tttgaacaag cgaatagatt tcttgatgct
     2161 ggtctgtttt acgcaacgct tcctcaaact ctcggatttc tgcagatttc gattttaaat
     2221 tggggcttat cgacaaaata taatctgcaa cggctatatt ttgatattta ggagaaaagt
     2281 attgatcgca ttcacttttt ttcaggtagc agtctgccat cagctgccgg agcaattgct
     2341 ggtaggcctg atttttcttt tgcagattca gtgctgtttg ccaatgaaca attttttgat
     2401 agaaatgttg gaaagacttg ataccaaaga taccttcata tggactatct gcttccagta
     2461 caaaaggaat attcgttttc agcagagatt ggacaagctg ctgcgtttgt gaagctgatc
     2521 ggtataatat gattgattcc ttatatttcc catttttttg aataaatgtc tgaatttgtt
     2581 tgattagcca ctgactttct gctttagtat cagaaaacaa ataggcttcc ataacacctg
     2641 cttctttttg tgctggaatc atcgcctttg gtatccgatc atttttatta tagctgatca
     2701 atctatttgc tccttggaca atagctgccc gagaacgata attagtcaat aagaaaagag
     2761 ttttggtagg atattctttt tcaaagttct tgatgtatgc tggctctgat cctctgaatc
     2821 catagatact ctgatcatca tctccaacaa caatcaactt gatcctgttt tcctttgtca
     2881 tccgtttcac gatttcccat tgaagtggat tagtatcttg aaattcatca atgaatagat
     2941 aatcatattt ttggccgata taatgctgga tctcctcatt ctccaaagcg cttttcagat
     3001 tttggagtac atcattgaac tctagcaatt gctggcttct tttttgttct tggagttccg
     3061 tgagcaatcc atacagtcgt tctgatatcg gctgtcgtgc attcttatca atggaatcat
     3121 atttttcttt aactaactga accatttctt ctactgaaag gttcatattc tgccaatagt
     3181 ctaaccgaga agcaatcgtt ttttctccat attgatcaaa tatataaaga ttatatttac
     3241 gtatcagctg ttgcaaaaca gcattcactt tttgtgcagt atcctttgaa aagtctcctt
     3301 gtattccttg cattgctact tcaggaaatt ttcgacaaat ttcattgtat atcctaaaaa
     3361 agatactatg gaatgttccg atatggacag cggtttttct ctggctgaaa ttatctactc
     3421 gtttttttag ttcatttgca gcgttccttg taaaagtgat cattagtatg cgttcttcgt
     3481 ctacttgttt ttgcgtcatc agataaacag cttttgcaca gattgtttgc gttttgccgc
     3541 tcccagctcc tgctatgatt cgaagatgtt tcttcatatc atatgtgata gctgcttttt
     3601 gttcttgatt gaagcgatta taggaacgtt tctccatcat tttaaagaaa gagctgtttc
     3661 cttcactttc ttttacttgt acttcttcct caataagtcc gggtgcttcg ccataagccg
     3721 cttcataggt agcaatgatt tcttcttgta gccgaaagac ttgttgaagc tttttatact
     3781 tgttctccca gcgtttcaat tctttttgta atcggagaat ttctttttca ttcaactgat
     3841 tgatttcctt cccatctttc ttctttgaat ttgtttattt caagttggtt atttaaagtt
     3901 tcgttgtcta ttttttcttt atactaacag acctttctaa aaatgaaaat gggaagcgat
     3961 atgattttag ttttctgaaa atttttcctt tttttcaatc gtttatgcta agataaggaa
     4021 gacaaaaata ttcataaaag gtgatgaaaa aaatgcagac ttcctttcac gaggggcgta
     4081 caataggact tttgctgaca tttatcggag gagccatgga cagttatact tatatccaat
     4141 atggtgcttt tgcctctgct caaactggca atatcattct atcgatcatc caagcatttg
     4201 acggagaatg gctaagtgtt ggtaaaaaag tattgtctac ccttttcttt ttcttaggga
     4261 ttcttctaac aaagtatcta attgattatt ttagaaaaaa agaaaaacat ttctggcgct
     4321 tgtttgttct atattatgaa gcagtgattt ttttctttgt tagtttgaca cccgtccatg
     4381 agcatcccgc attagtaacg attttgattg cttttactgc atcgatccag tgggtagctt
     4441 ttgataaaat caacgggcgt gcctacacta atttatttac aactggaaat ttaaaagggg
     4501 tagcaacgaa cttatatgat tattgtattt ctaaagaaaa agcagatttt gatcgatttt
     4561 tccactatct aagtgtcgtt cttgccttta tcgcaggagc tattgtcctt gttttctgtc
     4621 atcatctgtt tggcgcccat tcgattttga tcgtttccat tttatttttg atcatggccc
     4681 tcactcagac atttcattta tggcaatttt atcatacgaa tcggttcact atttgatctc
     4741 aatgaatcaa aaaaactaag caagatgctg ctcacagaga aat
//
LOCUS       DASHXG010000111         4623 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.120, whole genome shotgun sequence.
ACCESSION   DASHXG010000111 DASHXG010000000
VERSION     DASHXG010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.120"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(584..1402)
                     /locus_tag="U2R59_002734"
     CDS             complement(584..1402)
                     /locus_tag="U2R59_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEM8967062.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1563..2252
                     /locus_tag="U2R59_002735"
     CDS             1563..2252
                     /locus_tag="U2R59_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEM8967063.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2266..3768
                     /locus_tag="U2R59_002736"
     CDS             2266..3768
                     /locus_tag="U2R59_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8967064.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3781..4257
                     /locus_tag="U2R59_002737"
     CDS             3781..4257
                     /locus_tag="U2R59_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8967065.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1546 a          665 c          817 g         1595 t
ORIGIN      
        1 aatataaaaa tcaaaaggat cataaacttt taacaagtga tgaaatgggt ggaaattgat
       61 tcttatagac agtttgtctc ataacattga agtattttgc aattttagca ttgaaacact
      121 tttttaatct tcaacgttgt tcttataaac aagatgattg ggaatctttt gaattaacac
      181 tgtatagctt agaacaccct ttatagaaaa cattcgctta gcaatcttaa taattccttg
      241 tgcccgatgt cgtttagatt cagtaggttc ctgctcatcg atcatggaaa aaatttgaag
      301 gatcagatcc ttaataaatt tatttaagag aggatgatcc attgcttcat ccatactcga
      361 taaactagtg ataatgagct acacgttttt ctttcaagtt gatcaatagc ttccacgata
      421 aaaatatctt tagataaaat caagaaccgt aggaactaca gggatatttg gtcaataaga
      481 gccaccgcta ttagtaaaaa ataagctatc aagtatgctc tcatcccaag aattgcctac
      541 ttcaatcgtt aaaaaccgtt aggtttagct aagtgggggt agttcactca atacttttat
      601 caataataga gcgcaaaact ttttctctta attcaactga atcaatatta ttgttttgtt
      661 cataaccatg aactaataga tcacaaatat aaagttgtga tatttttcca gctaaagatc
      721 caccattaag aaattcttca atggctgttt gtaaaactaa gtctgcagac tttcctatag
      781 gtgaatgaat atagttagtt atagcaataa tttttgcgcc atttttttta gctattttca
      841 atgaatcata agtatctttc gttttcccag ataaagaaaa aatgattact aaatcattaa
      901 ctgttaataa agaagcgact tgggcttgaa aatgagggtc tagtacagct tttgcttgaa
      961 ctcctacgcg aagaaacata ttttctaaat caagactagt atttccacta gatcccactc
     1021 caaatatata tatgtttttt gattgagtga tcattttaat ggcttcattc aatttttctt
     1081 cgtctaaaag cctaatagtg gaatagagag cttctgttaa actattagca atttcatcat
     1141 agtactttac actagtcgga tgttcttttt tttgactaaa gtcttccttt gcaatttcaa
     1201 tttttaaatc agaaaaacca gaaaaaccaa ttttttgaca aaagcgaata atagtagcat
     1261 cgccaacttt tgtgtttttc ttaatatcac tcatcgtact ataaataata gttttcccag
     1321 aatttaaaat aaaatcagcg actttttttt cagacttcgt taaaaatgga taattttctt
     1381 taattaaata gatataactc atacaaactc ctctacaatt tcaacttttc tccattatac
     1441 tccaaaataa taaaaaaaac tcctaaatac tccattttta tctttacttt tatgaaagcg
     1501 gatgctatat tgtttttgga gttgttatcc aaaaataata aaaaattgga gtgtttagga
     1561 taatggataa aaagaggttt ttagatctta tttcaaaagg tttgattgtt tcctgtcaag
     1621 cattacctgg tgaaccattt tacaaagagg aagaaagttt aatgccttat tttgctttgg
     1681 ctgctcaaag ggctggagca gttggtatac gtgcaaattc tgttcgagat attattgaaa
     1741 ttagaaagtg tgtatcatta ccaatgattg gaattattaa aagagattat ccaccagaat
     1801 ctccattcat tactgccact atgagagaag tagatgaatt agtagaaacc ggtgttgagg
     1861 taatcgctct tgattgcact cttagaaatc gacatgatgg actatctata aattctttta
     1921 ttactaaaat aaaagaaaaa tatcctcatc agttatttat ggcagatatt tctacatttg
     1981 aagaaggcaa aaatgcatat aaagcaggaa tagattttgt aggaactact ttaagtggat
     2041 atactgagga aagtaaaaaa caagatgggc cagatataga tttgattaaa aaattggtag
     2101 aagaagggat ttgtgtaatt gctgagggaa ggattcatac tccagaacaa gcaaaagaga
     2161 taaaaaaaat aggagttgca ggtattgttg tgggtggtgc tattactcga ccacaggaaa
     2221 ttgcatcaag atttgttaaa gcattaagtt agggggagaa ataaaatgtt taaaaaattt
     2281 tcacaattag gacgcgcttt catgttacca attgctatat taccagtagc cggattacta
     2341 ttgggactgg gaggagcgtt aacaaatgag agtgctataa atgcttatcc atttttagat
     2401 caaccgtggt tgcatacaat tttaagtatt atgagttatg ctggaaatgc agtttttgca
     2461 aacctagcac taatttttgc aattggtatt gctgtaggac ttgcaaatgg agataaagga
     2521 acagctggtt tagctggtgg agtagcttat ctagtatata ctgcaactat tagtgggttt
     2581 cttgaacttt tttcagcaaa agatgcaaca ctagatacag gtgtagtggg atcaattgtt
     2641 gttggtggta ctgttgcatt tttacacaat cgttatagaa aaattgaatt accacaattc
     2701 ttaggttttt ttggaggatc aagatttatt ccgattgttt ctagtttagc tgcaatcatt
     2761 attggttctt tcttttattt aatttggcca ccaattcaaa atggtttagt agttgctggt
     2821 gaacaaattg cccaaatggg tagtttagga acttttttat atggtttttt attgcgttta
     2881 acaggtgctg ttggactaca ccacaccatt taccctttgt tctggtatac atctttaggt
     2941 ggtaccgaaa ctgtagctgg atcaacaatt gctggagccc aaaatatttt ctttgcccaa
     3001 ctagctgatc caaaccacac tggtctgttt acttatggta ctagattttt tgcaggaaga
     3061 tttgcaacaa tgatgtttgg attaccagca gcatgttatg caatgtatcg tgcaattcct
     3121 aagaaaaatc gtaaaaagaa tggtgggctt tattttagcg gggcccttac atcattttta
     3181 actggaatta ctgaaccagt tgaatatatg tttttatttg ttgctccttg gctttatgtg
     3241 attcatgcat tcttagatgg attatctttt tattttgctg atatcttaaa tattcgtgta
     3301 gggaattcct tttcaggtgg tttgatcgac tttttattat tcggtgtact tcaagggaat
     3361 gacaaaacta attggttaaa attaattcct tttggtattg catgggcatt tatatatttc
     3421 tttgttttta cattctttat caaaaaattt aaggtagcta ttcctggaat ggaagaagaa
     3481 tcagaagttc attctgaaaa agtaataaac aaaaatacat cattacatga agagtctctt
     3541 atcattattg aagctcttgg tggaaaagaa aatattgagt ctgttgaagc ttgtgcaact
     3601 cgtttgcgtg ttgctgttac gaatggggag attattcaaa aacaaacaat aaaagacact
     3661 ggtgcaactg ctgtcttcga agtgaagggt ggcatccaag ctgtttttgg agggaaagct
     3721 gacttattaa gtcaagaaat caatcaaata ttaggaaaag ataattagga ggtttttaat
     3781 atgtttgaaa ttttcaaaaa gaaaaaacaa gaaacttttt atgcaccttg ttccggaaaa
     3841 atcatttcca tcacagaagt aaatgatcct gtcttttcac aaaaattact aggtgatggt
     3901 tttgccgtca tacctgatgg ttcaaaaatt tatgctccat tggctggtcg agtaacaaat
     3961 atatttccta ctaaacatgc tattaatata aaaagcaact caggcattga ttatttgatt
     4021 catattggaa ttgatacagt tgaattacaa ggagagcctt tttcgatttg tgttcaagaa
     4081 aatgatgagg ttactcctga aacctcgttg gttgatgtgg attttgacaa aataataaaa
     4141 tctggtaaag atacttctgt tatagttgtt tttccggaga aaaatcagtt caatgattta
     4201 ataatagata atggtcgaat tgctcatggg aattcatgtg gaaaaatcac tttttaaaaa
     4261 agtgtatata aaaagctata aaataagcta aataggatat ttgtcaaatg aagttggtga
     4321 acagaaagaa ctgttttctt tctgttcatt tttttatttt attagtaatg attccccatg
     4381 ccaaatcatg atccgtaatt taaagttata aaagcttcga aatccattgg catttccttg
     4441 gaataccttg atatgattat tcaaatataa aatatagaga gaagagagag agggaagata
     4501 tttataaagg gcaaagttat gtttactcaa cttaggaaat agaaatagat caatttatat
     4561 tctcttgtca atcgaatatg aaccttagca ctatatacca aatatagtaa aatgctgaaa
     4621 gat
//
LOCUS       DASHXG010000112         4587 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.121, whole genome shotgun sequence.
ACCESSION   DASHXG010000112 DASHXG010000000
VERSION     DASHXG010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.121"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            186..2855
                     /locus_tag="U2R59_002738"
     CDS             186..2855
                     /locus_tag="U2R59_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEM8967066.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="U2R59_002739"
     CDS             complement(2946..3566)
                     /locus_tag="U2R59_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEM8967067.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="U2R59_002740"
     CDS             3680..4219
                     /locus_tag="U2R59_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967068.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="U2R59_002741"
     CDS             4216..4554
                     /locus_tag="U2R59_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HEM8967069.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DASHXG010000113         4433 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.122, whole genome shotgun sequence.
ACCESSION   DASHXG010000113 DASHXG010000000
VERSION     DASHXG010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.122"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(21..221)
                     /locus_tag="U2R59_002742"
     CDS             complement(21..221)
                     /locus_tag="U2R59_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEM8967070.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(674..994)
                     /locus_tag="U2R59_002743"
     CDS             complement(674..994)
                     /locus_tag="U2R59_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967071.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1497..2615)
                     /locus_tag="U2R59_002744"
     CDS             complement(1497..2615)
                     /locus_tag="U2R59_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967072.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            3086..4393
                     /locus_tag="U2R59_002745"
     CDS             3086..4393
                     /locus_tag="U2R59_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEM8967073.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1393 a          891 c          773 g         1376 t
ORIGIN      
        1 tattttttag tataggttaa ttaagcttta gtaacgtttg ttgcttgagg tccgcgttgg
       61 ccttcttcaa catcgaaagt tactgcttgg ccttcttcta aagttttgaa tccgtcgcct
      121 tggatagctg agaaatgaac gaatacatcg tttccgtttt ctgcagtgat gaatccaaat
      181 cctttttctg agttaaacca ttttactgta cctgtttcca taataaaaat cctccttgtg
      241 tatcaacaca tattttgcaa ttacttgaat ggtgtatatc tggaagatgt ttatttgaaa
      301 caagctacca cagattaccg aacaaaaact actcctatag tatatcatac cgtttacaaa
      361 aaagctagag tttttcgact ttttttatta aaaaaagttt tctcagcgat tacataaagt
      421 gaaaaaccga actttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc
      481 tgatgttctt ttttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca
      541 acggtcgagg ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag
      601 cctatgacag ttaccagaag aacaaggcaa accaatacga ccaacgagat tagtttttct
      661 tttttgctca tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat
      721 gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac
      781 aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag
      841 gaatcgcaga atcaagatct ggtgtctgta cataaacatt tttgtacaga cgtgtgcctg
      901 taataggaaa ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata
      961 gagacagcaa acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt
     1021 cccaattaaa atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt
     1081 ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt ttttaaacgg
     1141 tgttccagaa gtagcttctt cggaaataag ccgaaatttc acaaaaattt gagaaataat
     1201 ttttgtcaat ctcttcttat ttcttgaagc tgaccacttc tgtcacaacc tcttccttaa
     1261 acggtgttca aaagcttgca tctgcggtaa taagcccacc aaacaaaaaa tatgaagagc
     1321 tatttttgct tgctgttctt attacttgat gcagaacagc tttttcacaa cctctcatac
     1381 acggtgttta atcagctgac cttcggtatt agctcaaaaa acggcaaaat atgtgaaact
     1441 atttttccgt ttgtttctct aatactcagg tcaaaacact gatttcacaa cctcttttaa
     1501 taacgaagaa tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac
     1561 acttttccgc cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca
     1621 tattctgttt caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa
     1681 tgtgacactt ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc
     1741 ttatctaaga gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc
     1801 ttcgcccctt cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg
     1861 tctgcacaat aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaga
     1921 gcaaataaat aaatcggcca ttgttctgga ttttcgaaag aatccttcaa gtacgtatca
     1981 actgcttggt aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca
     2041 tggaaagtta ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca
     2101 cctgtcagtt cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat
     2161 acttctttta cttgtttgtt gctgacttca tacaatttca tggagtcgcg gttcaatccc
     2221 aataaataat aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga
     2281 tcacttacat agtattgatc gtctaccggg atactcaaac gatggatata ggtttggtca
     2341 gcagttataa tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac
     2401 aaattttcaa ttttttcttg gaacggggac cagtcatgtt cggaatattt tttctcaaaa
     2461 cgtttctttg cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga
     2521 tgggcgacat gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc
     2581 aattgtgaca ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca
     2641 ttcctttgtt tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc
     2701 taaaaaaata aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat
     2761 aatttcctca attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta
     2821 agaaaaagaa taaaagaggt ggatcttatg catttgatta tgattttcag tttattaagt
     2881 attatcagtt tatttgcttt cagcgcttcc cgcttattag atgcggaaac acagcctatt
     2941 cctgtaaaag tacgtaaaaa cgaccgctaa ccttccataa cgtgcgttct tatcctaaag
     3001 ttttttcaga aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa
     3061 caaattaatt acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt
     3121 ggctagtctc attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga
     3181 tactttcaaa gtaaatgcaa aagcagcctt tgctgtagat gcgcaaagcg gtaagattct
     3241 ttatgatcaa gatggagaaa aaaccatggg gatcgcttca atcacaaaaa tcatcggtct
     3301 ttacatcgtc cttgatcaag taaaagaagg gaaactatca tgggatgata aagtttcaat
     3361 ttcagattat gcagaaaatt tgagtgtcac cccagattta tcaaatgttc ctttgcataa
     3421 agaaaacacc tacaccgtta aagaattatt cgactctgca atcatccagt cagccaacgc
     3481 ttcaatggtt gccttggcag aaaaaatctc tggcagcgaa gcaaaattca ctgaacgaat
     3541 gaaagaacaa ttgaaagatt ggggtatcaa agatgcaacg atcgttaatg catcaggact
     3601 gaataactct tatcttggcg aaaaccgacc agaaggtact ggagaaaacg acgaaaatca
     3661 aatgtctgct caagatgtgg ctatcgttgc ccgtcatttg atcttggatt ttccagaaat
     3721 actggatgta tctagcacta cgacacaaat gtttggcgaa aacacgcaat caccagtaga
     3781 aatggtcaac tggaactgga tgctcccagg attcgtgaat tataaagaag gcgtggacgg
     3841 attaaaaact ggtacgactg aacttgcagg agcctgtttc gtcggtacga tcactaaaaa
     3901 cgatcaacga atcatcactg tcgtattgaa tgcagacggc catgcggaaa acccaagtgc
     3961 ccgtttcaat gaaacagctc gcttaatgga ttattgctac gacaattggt cagaaaaaga
     4021 gcttggaaaa gccaatgcaa gtatccctag tctaaaaacc attgatgtaa aagacggaaa
     4081 agaatcaaca gtgcccgttg tgcttaaaag tcctgtaaaa gtatgggtac ggaacgatat
     4141 ggatactgga aaattaacaa tcacaccaac tcttgacaaa aaacaagtca ctgacaatga
     4201 gatccaagca cctatggata aaggaacaaa aatcggtacc gcaacgatca ccttggcaga
     4261 agataaatta ggttatcttg aagacaacaa cgcgccatcc acagaaatca tcacggataa
     4321 aaccgtagaa aaagcaaata ttttcgttat tggctggcga cgcgtcgcag aatttttcgg
     4381 taacttgttt taattgaaca aaaagaaaaa agcatctttc catgtggaag atg
//
LOCUS       DASHXG010000114         4433 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.123, whole genome shotgun sequence.
ACCESSION   DASHXG010000114 DASHXG010000000
VERSION     DASHXG010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.123"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(543..2048)
                     /locus_tag="U2R59_002746"
     CDS             complement(543..2048)
                     /locus_tag="U2R59_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEM8967074.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="U2R59_002747"
     CDS             complement(2045..2731)
                     /locus_tag="U2R59_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEM8967075.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="U2R59_002748"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="U2R59_002748"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEM8967076.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DASHXG010000115         4305 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.124, whole genome shotgun sequence.
ACCESSION   DASHXG010000115 DASHXG010000000
VERSION     DASHXG010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.124"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            148..1137
                     /locus_tag="U2R59_002749"
     CDS             148..1137
                     /locus_tag="U2R59_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEM8967077.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="U2R59_002750"
     CDS             1134..1553
                     /locus_tag="U2R59_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967078.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="U2R59_002751"
     CDS             1532..1870
                     /locus_tag="U2R59_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967079.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="U2R59_002752"
     CDS             1874..2236
                     /locus_tag="U2R59_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967080.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="U2R59_002753"
     CDS             2458..3864
                     /locus_tag="U2R59_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEM8967081.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1497 a          602 c          996 g         1210 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DASHXG010000116         4284 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.125, whole genome shotgun sequence.
ACCESSION   DASHXG010000116 DASHXG010000000
VERSION     DASHXG010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.125"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..237
                     /locus_tag="U2R59_002754"
     CDS             <1..237
                     /locus_tag="U2R59_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967082.1"
                     /translation="IYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSA
                     ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(490..639)
                     /locus_tag="U2R59_002755"
     CDS             complement(490..639)
                     /locus_tag="U2R59_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967083.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1101..1313
                     /locus_tag="U2R59_002756"
     CDS             1101..1313
                     /locus_tag="U2R59_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967084.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1591..3390)
                     /locus_tag="U2R59_002757"
     CDS             complement(1591..3390)
                     /locus_tag="U2R59_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEM8967085.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3514..4110)
                     /locus_tag="U2R59_002758"
     CDS             complement(3514..4110)
                     /locus_tag="U2R59_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEM8967086.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1529 a          749 c          733 g         1273 t
ORIGIN      
        1 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
       61 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      121 attcaatctg ccgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaaca
      181 cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaactt aatttgacaa
      241 ttaagattat attaaatatt atacagataa taacggaata ttatcatcga aacagctaac
      301 aaaattgtca taaaaaacga gatggttgat attagaactt gtgtttttgt ttaggtctag
      361 agataaagag agacaatttc caaatatatg taatgaatac aaaaagacgt ttgtcgcgga
      421 ttaccgttac aaacgtcttt tattgatttt ccgagatctc atcagtcgcc atttggaatg
      481 gttcactcct tatctagatt cgtttaatgc tcggactgct tgttcgattg taataccaaa
      541 cgcaacgtta ttttcgtttt gtgcatcaat cgccataaaa cggttagaag ttgtatcaaa
      601 agctacgcgg tattgcatat ttgtttttgt aaacgtcata aaattcatct cctttgtaat
      661 gtaatttagt tcttgaaagt ttcctttaaa ctttcgaact tataccaagt ttagcatcgt
      721 acgttttttg atgcaattaa aaagcattta tcattttcct tatttatttt ttcttaaatg
      781 gtttagctat tttcttttaa tccgataagt agcccaatca tcaaggttac aaatactatt
      841 gcttgaatat aaatcatatg ctcacctctt tataaataac ttagcaatat aaagaaaaaa
      901 acgcacgaac aacataggaa tataaacaaa cgtttttgtc acaacgtcta agatcgtgtt
      961 aaaaaatagt tatctaaaaa gcagaaagat actcaaaata aaaaataaaa aaatggataa
     1021 aaacgttttc aaatacaagg taatttgtta ttataaaata aagaaaaaac aaaataaaaa
     1081 taaagaaaag agggaatgaa atggtaaaag cagaagtagg aagatcttat atatgcaaac
     1141 cgatcggagt atctcatgaa ctaatcggct gtattgaacg tacatatatc aacacggctg
     1201 tcgtgtatgt tgaaagttat gaccaacgag actatcaact tatcaatgaa agcaagtatc
     1261 gcatgctcgt aaaattctgt gatattagcg cacctgctga attggtttct taaacagtat
     1321 ttttgagaat tcgcaagaac tcccttataa tataaataaa gacagaaggg agcgagaaga
     1381 tatgccaaaa agaaaaagtt cagggaaaat gggaattatt cttgcagtga tctctgcaat
     1441 tcctgctatt ttagctattg ttcgtgcgat gaaggaatca agagaaagtt aagcacacat
     1501 tatgagcgtc aaacaaaaaa cgcatatacc tgcggtggca ggttatgcgt tttttgttgt
     1561 ataaagactt ttttcattaa cgatttttga ttagccgact cccaaaacaa aatttagcag
     1621 tttatctgaa taagtgattt cttcatctgt ttgtttcaca ctttcattta gtagtcccat
     1681 ctcatcggtt atgataccat ccacaccata aaacatcatg cgactcatag catctgaatc
     1741 gttgattgtc catacatata cttcttttcc gtcttggtgg gcagaattaa tgaagttacg
     1801 gttgatcgta ctatattcca ttgtcagaaa atcagcaggc gtcacagggg gcccaacaat
     1861 attgaaaggt aagatgtagc ccacataaaa gtttggttct gcttctttta aatctgaaac
     1921 ggtttggtac gtcaaacttt gcaaaatatg atggttctct aagataactt tgcggtattt
     1981 atggacaaat cgttcgacaa ggtcatccga atctttttta gaggtcttga tctcaataag
     2041 taatttttgg tttagcttat gtgctttttc caaataagaa tcaaaagaac aaacaggggc
     2101 ttgcactccg ttttcagtaa ctgtaagatt tgtcaattct ttcaatgtaa gatcctgtgg
     2161 tgttccattt acccctgtta agtgacgaag atttgcatca tgcatcacta cgaaatgacc
     2221 atcttttgtt tcctgaacat ccatctctac ataatcagga tgatagtctc tgcttgtttt
     2281 ttcaagtgct tctaaagtat tttgcgcccc attttgggta ctcacacctc tgtgagagac
     2341 agtcactggt tttgtctgaa cagctgaagt cagataatcc atattgtaaa gacagacgcc
     2401 aataccgaaa aaaactgcaa aaagagtcaa accagtgttt ttcagcgcag agaaacgcaa
     2461 gttgggggct tgtgggataa accacttagg gatctcaggc aagaagcctt cgtcatccat
     2521 gaaatcaaca atgatataaa aaatccctac ggtagacatc acgatattga ataataaaat
     2581 cccttgtaaa agcgtcatag caaacacagc gctgatcaat gcatagtctg ggaaaaattg
     2641 ttcaaccata ctttgtgcca aaataacaac gatatatcct aaagaagaaa ggagtaaaat
     2701 cgtaccgcca atcacaataa attggcccgt gatggccaaa agacgcgatt tggtcaatga
     2761 ccagctttcc cgaatggctg ctcgaaaagg acgatctcgt agaatcattt ccggtaaagc
     2821 aaaaatcagt cgaatcccaa tatagccaag gaaaatataa acgagtaaaa aggaactgac
     2881 gatgatccaa cgattagcaa aaataaaatc cataatgaaa gcggggattt ttatttttga
     2941 cagtagatca gaattaaaac ttaatccgct gatcggtaga atcaataaaa aataagcaag
     3001 gaaaaacaaa aaagtaatgg gtctcacttt cttcagctga agtatcgtca agtgtaagag
     3061 ttgcttcaaa gagattggtt ctttcttttt aataaaaaaa acactcatca aaagaaaagt
     3121 aaattcgaaa taaactaaca gtaaaatcgt catcaaaact acgattaacg agagtagaac
     3181 cccaggatgt tgagaaaaaa ttgaaggaat attgtcataa gacaaatagt caattgcccc
     3241 tcggtgtaaa ataaaacggg tcgtactgct caataagggt aaacaaataa ataaaataaa
     3301 gccatgcatc agcaagacat cacggaaata agcttgtgtt ccttttaaaa agtcccaagc
     3361 attacctaag ctacgtttca aataattcat cctatcacct gctcttcaca ttgtagcgca
     3421 aatctaatga aaaaggaaag ggtgcagtgt gttttgcaga ccctttccca gatttaacat
     3481 tgtcaatcaa tgactaattt tacaaaataa atattatcca agaagaccac ttagatattg
     3541 acctccataa atcaaggcca tactatataa gaaaatcgac agtggtttag caatcaaaat
     3601 gattagtgta tatcgtttca ctgacatgtt tgtcaatcca gccatcaaac ataacgcatc
     3661 gtcaggagca actggaagaa aaatagctag agcaaacagc ttctcaaaac ggttttgatt
     3721 atccagccag ccaatatatt tgttatatgt cttatcgcta atcatggaaa gtatgaatgg
     3781 ctttccataa cgacgcccta gcagaaaaat gataatcgaa ccaatgcaga ttccaatata
     3841 gttatagata aatccagcat aagggccaaa tatcaggaca ccagctgcag tactgatccc
     3901 tccaggaatg attggaataa ctacttgcag gatttggatg aagacaaaaa taatcggtcc
     3961 taaaatgatg gaatcaccta ctaatcctct taacgcattc aaatctttga aaacacctaa
     4021 attaataaaa taaatcgtca gcgcgattga taggcctaat ccgataatgg atatgaaatt
     4081 tatcagtttt cgagaggcag caatattcat tattcatcaa ctccttagag gttctttgtt
     4141 aactatactt tactagaaaa gcaactaact gcgccatttt ttgatatgac agaaaacaaa
     4201 caattttgta agttcatcat aagtataaaa gattgatctc aaaaaaacat ccaactaaag
     4261 acttatttaa taacttgttt tttt
//
LOCUS       DASHXG010000117         4178 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.126, whole genome shotgun sequence.
ACCESSION   DASHXG010000117 DASHXG010000000
VERSION     DASHXG010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.126"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..993
                     /locus_tag="U2R59_002759"
     CDS             <1..993
                     /locus_tag="U2R59_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967087.1"
                     /translation="DGPYWLGKVPLGENIADHTVKFPIESGDHQIYQGYTEEELMIGQ
                     TYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVASSPKLFRV
                     YQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVED
                     NLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANATAIDEL
                     DNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSSGGNDSTILTIP
                     EGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            1010..1159
                     /locus_tag="U2R59_002760"
     CDS             1010..1159
                     /locus_tag="U2R59_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967088.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            1156..1602
                     /locus_tag="U2R59_002761"
     CDS             1156..1602
                     /locus_tag="U2R59_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967089.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            1604..1741
                     /locus_tag="U2R59_002762"
     CDS             1604..1741
                     /locus_tag="U2R59_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HEM8967090.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            1779..2072
                     /locus_tag="U2R59_002763"
     CDS             1779..2072
                     /locus_tag="U2R59_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967091.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            2069..2293
                     /locus_tag="U2R59_002764"
     CDS             2069..2293
                     /locus_tag="U2R59_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEM8967092.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            2290..3315
                     /locus_tag="U2R59_002765"
     CDS             2290..3315
                     /locus_tag="U2R59_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HEM8967093.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            3505..3578
                     /locus_tag="U2R59_002766"
     tRNA            3505..3578
                     /locus_tag="U2R59_002766"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3539..3541,aa:Ile,seq:cat)
BASE COUNT         1428 a          713 c          844 g         1193 t
ORIGIN      
        1 gatggccctt actggttagg taaagttcct ttaggcgaga atattgccga tcatacagtt
       61 aagttcccaa tcgaatctgg cgaccaccaa atatatcaag gttacacaga agaagagctt
      121 atgataggtc aaacgtatac tatcacgctt aaaggaacaa aacccgcaag tcaaaccttt
      181 gtagcgtata atcattggac tgctcgttta ggagaactaa agccagttga tgggttgaca
      241 gacgtatggt ctctaacatt cacaccaacg aatgttgtgg cgagttcacc taaacttttt
      301 cgtgtttatc agtatccaca atcaacagta ggcgcatgcc ggatcgactg gctcaagatt
      361 gaaaaaggcg acacacgaac cccgaatatt agtgagtata aatatcgtgg tactggtatg
      421 cgtgattcaa acaatccaaa agattatgtt tgggatctag caccagaata tgtcgaagat
      481 aacttggcca cagatattaa aatttctgaa attactggta aagcaaacaa ttataccgat
      541 gggaaagtat cggagattaa ttcgcagttg actgcttcaa ttaatgaagt agacaccaca
      601 gctaaggatg ctcaaacaaa agcgaatgct aatgcgactg ctatagatga attagacaat
      661 aagatcgatg aacgcattaa tgatacagct actaccacat taacagttac aaacgggaat
      721 accggatcag caaagcttta tcgtgaagga aaaacagttt ctatatattt tgtggcttta
      781 aacggaaaaa gcagtggtgg aaatgattca acgatactaa caattccaga aggctatcgg
      841 ccaccaatta gttttgagca actggttggc tcgatagacc gttctacttt gaacagtgct
      901 cagttatcta ttggtgcaga tggagccatt aaatggcgaa gaaactcaag ttatggatcg
      961 gattatacct ttgcaattac ttacacgatt tagaaaagcg tgaatcgata tgaaggcagc
     1021 atatagacca attgaacctt acggattcga gcaaatcatt gtgaatgatg aagaacattt
     1081 accggaagaa tgcacagaag tcgaaccacc gattccaaat tggaaaccga aattcaatta
     1141 ctgggaggga aataaatgaa aaacatttgg aaatatggac gtactggcgg agagtacgca
     1201 ggaaaagtat tggacgacat gcttgtatcc gttccttaca cagatcagcc accgcttgaa
     1261 ggaattcgtg ctgatggcga accgttaaca atcgctgatc aaatgtttga tcctaaattg
     1321 aatcaatgga ttattttagc gaacgcacta gatcacaacg atttaaacaa tctcaaagca
     1381 atgtatgagt cgttagaaaa tgagaacggc gatttaaaac agatcaatgc caaactcatg
     1441 ctaagcgatg tagcaattaa acaggaaaat actgcattga aagaaaaagc ggatagttta
     1501 gcacaaatca attcaaaaat gatgcttgct tcgttacaaa atagcaaaga catttcagaa
     1561 attaaagagc aactaaatcc agcttcaaag ggaggtgagt agtatgttta gttttagcga
     1621 tgtgaaaatg atgtatgatt ggggctgttt cactaacgaa caagtaatgg ttttcgttcc
     1681 gttgtgcatt actgaagaaa aagcagataa aatcattagc aaagaagaga gcgcatctta
     1741 attgatgtgc tttttatttt gattcaagga gttgtcacat gattaattta ggggaatggg
     1801 gagcgatagc aggatcaata accgctatcg tttctttgat tttattagta ataaaaccaa
     1861 ttactgcatc tttctcgaag attactgaga ctctttcaaa agtaagtcac aatttagatt
     1921 tgctgactaa agatttagaa tcgagcaaat cagatcgatt gatgattcat gaagaactaa
     1981 agaaacacga tgaaagatta gatacacatg cagaaaaatt ggtagaacac acgcaacaaa
     2041 ttaaaacttt atttagggag agaagaaaat gaataataaa acgttcgaag tactaaaatg
     2101 gttcgcactg gtaattattc ccgcactagc tactttcgtg gggttagttg gtaaagcgct
     2161 caattggcag tacacagata tctgtgttgt catcattact ggttttggcg cgtttttagg
     2221 gagtgtgttg ggtgtatcaa atcgaaccta caaaatgttc tcggctgaaa gcgaagaagg
     2281 aggaaacaaa tgaaaaagaa aattactatt actgcgatga gcctgttaac ggctcttttt
     2341 ttattaccca ttaatacgtt tgcttatact attaatgacg agtataattt agcgccgaat
     2401 caaggagact ccagattagc aattcctaac aaaattattt tgcacgaaac tggaatagat
     2461 gcaccagcaa gaaacgtagc cgccaacatg aaaaataatt ataacggaag caattcttat
     2521 actacagatg ttattggtga cggtgggatt gtttaccgtg tgggtgagca aggatatgtt
     2581 tcgtggggag ctggtaacgc taatccttat gcgcctgtac agattgaatt acagcgcaca
     2641 tatgataaag cattgtttga aaaaaactat cgagcttata ttgaatatac aagagatagt
     2701 gcaaaaaaat atggaattcc attgactctt gatcaaggaa cttctttatt tacaaaagga
     2761 atcatttctc atttgtgggt gacaaattat gtttggggga accacacaga tccatatggt
     2821 tacttatcgc aaatgggagt tagcaaagaa aagcttgctt atgatttagc tcatggattt
     2881 accgatgaaa atccaacaac ttctgaaaac aagcctgtca ttgatccaac acgagctggt
     2941 gcagctaatc ctacgctgac agatggaaca aatcacgccc acattgatca gtttggggaa
     3001 atcgaaaacg caaacttgca tgtggctgga tggcacattg ctaactataa atacgagtat
     3061 attttcatta tggactacaa tactgggaaa gaattagctc gagtaagagc tgatggaatt
     3121 tatagaccag atgtaaacca agcttataat acttctggaa atgttggtta tcatgtatct
     3181 ttcaatatgc gtaattttcc tagtaagaaa gtctatgtaa tgatgcgggc aacgaatgat
     3241 ccagagggaa acactaaagg cggtgcgcaa gatttccatg acaaacgttg gtatttaaat
     3301 attcctaaac gataaaaata gctcctcgtt gaggagcagt acataactat attgacaact
     3361 ataaaaatta ttcgataaaa tagtgatgtt atcgcatatc ttcactatca cccataaata
     3421 gtcacactcc aagctatgcg ataacaggtt tgttgccaca cattctactg gttgattgtt
     3481 tatggcttta tgtggcaaca accagtaccc ttagctcagt tggtcagagc agacggctca
     3541 taaccgtccg gtcgtaggtt cgagtcctac agggtacatt aacgtagcca tttgaatcgt
     3601 tctgtgttag aatttttttg aagagtatta tacaagctaa agcttttctt cattgccact
     3661 caaatgagtg gcttttttat gtatcctttt atggattaat gaaaggatgt ttcacatagt
     3721 tatacttctg tatatttgaa aagttttact ttgattttta aatagaaaga catttgggtt
     3781 aaattgtgag ataataataa agaagagttt aaagcgcacc ccaaaccact tccccataag
     3841 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
     3901 aaaaaagtga gaaaaaaggc ttacaattgg agtggtagtt aattagtgac ttatttttga
     3961 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
     4021 cttaaaaaat atctcctttc acaagtatgg tgataaaatt cgttccgggc taccttttta
     4081 ggtagcctac tttaatcttt atacctttct ggatcaacga aagtatactt tatatagtca
     4141 taacgccgat gatcgctacg tgcgtccggc acgtcagt
//
LOCUS       DASHXG010000118         4116 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.127, whole genome shotgun sequence.
ACCESSION   DASHXG010000118 DASHXG010000000
VERSION     DASHXG010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.127"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..85)
                     /locus_tag="U2R59_002767"
     CDS             complement(<1..85)
                     /locus_tag="U2R59_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8967094.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
     gene            155..316
                     /locus_tag="U2R59_002768"
     CDS             155..316
                     /locus_tag="U2R59_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HEM8967095.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="U2R59_002769"
     CDS             335..1612
                     /locus_tag="U2R59_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8967096.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="U2R59_002770"
     CDS             1622..2278
                     /locus_tag="U2R59_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEM8967097.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="U2R59_002771"
     CDS             2278..3654
                     /locus_tag="U2R59_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEM8967098.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3784..>4116
                     /locus_tag="U2R59_002772"
     CDS             3784..>4116
                     /locus_tag="U2R59_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8967099.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1629 a          455 c          727 g         1305 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg gagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DASHXG010000119         4063 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.128, whole genome shotgun sequence.
ACCESSION   DASHXG010000119 DASHXG010000000
VERSION     DASHXG010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.128"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            82..1431
                     /locus_tag="U2R59_002773"
     CDS             82..1431
                     /locus_tag="U2R59_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8967100.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1559..2149)
                     /locus_tag="U2R59_002774"
     CDS             complement(1559..2149)
                     /locus_tag="U2R59_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEM8967101.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2296..3648
                     /gene="brnQ"
                     /locus_tag="U2R59_002775"
     CDS             2296..3648
                     /gene="brnQ"
                     /locus_tag="U2R59_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEM8967102.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1169 a          744 c          789 g         1361 t
ORIGIN      
        1 ttttggaatc ttagttgtgt ttttcagaaa actctcttaa tatggaagta attaaacttt
       61 tttagttagg atgatttaaa aatgaatgaa gagcaagaac tgcagcgtgg actgaaaaat
      121 agacatgtcc aactgatttc tattggcgga gcgattggaa cggggttgtt tttaggttcc
      181 ggaaagtcta tccagctagc tggcccttcg atattgctcg cctatcttat tactggatgc
      241 atctgttttt tcattatgcg tgcgttaggc gaacttctgt tatcaaacac caataaccat
      301 tcttttctgg attttgttgc agaatatctt ggcaaaaaag cggctttcat cactggctgg
      361 acgtattggt tctgctgggt atcgattgca atggccgatt taacagccat cggaatgtat
      421 gtacgctact gggcgcctgg tgttcctcag tggcttcctg aactgattgc attaggtctt
      481 cttctttgct tgaatatggt ggctgtctca ttgtttggtg agttagagtt ttggtttgca
      541 ttgatcaaag ttgtagcgat cattgccttt atcctcgtag gagcttatat gatcctcacc
      601 cactatacga cagatattgg cacagccagt atcacgaatc tatggtctca tggcggattc
      661 tttccaactg gtgcaaaagg atttatctta gctttccaaa tggtaacctt tgcttttgct
      721 gggatagaat tagttggatt agtcgctgga gaaacagaaa atcctgaaaa agtgttgccg
      781 gaagctatca ataatattcc tatcaggatc atcttatttt acttaggatc tctttttgtc
      841 attatggcaa tctatccatg gaacagcttg aatccagata acagtccatt tgtagaagta
      901 ttttcggaaa ttgggatcac gattgctgct tccttgatca atttagtcgt attaagtgca
      961 gcagcttctg cctgcaacag tgcaatatat agtacaggac gtatgcttcg ttctttagcg
     1021 caagaaggca gtgcccctaa aaaattcaaa aagttaacaa cacatcatgt gccagggaat
     1081 gctttgacat tttctactat cgtcattttc atttctgtta tcttgaatta cgtgatgcct
     1141 agtgaagtat tcacactagt aagcagtatt gccactactt gtttcttgtt tatctggagt
     1201 atgcttgtct acacgcacat gaaatatcgt aaaagtatcc tcggcaaaaa agctcattca
     1261 tttaaaatgc cgttgtaccc atttagtaat tatctggtat ttctttacat ggcctttgtg
     1321 tgtgtcgtct tgttcctagg aaaagatacg agaatcgctt tattactaac acctgtgtgg
     1381 ttcttgcttc tattactaat ctatcatatg aaatatgaac gtaagaagta agaaagtagt
     1441 tgtgacagaa gtggtcagct tcgagaaata agaaggaatt tacgaaaatt gcttcttaaa
     1501 tttttgtgaa atttcggctt atttcttgga gataaaagct tctgtcccag cctcttttct
     1561 atttccccgg aaacaaccgc tgataatagg catctgcttt tttataggaa aaaatccaaa
     1621 taccagatac aaaaaaacgt ccgaataacc cgatcaacgg tacaaaaaag acaccggcaa
     1681 tcaagcataa gttaatcatc atggagataa gacttcgacg gtcctttgac aaaactctca
     1741 cgacatggga atctggttta tttgctttca tgatttgcct catcaagata ccaaaagaaa
     1801 aactccacat cgtgtatact aagacataag ccatctcagg ccaaaaagct tcagggttac
     1861 gcccgaccca actagtaaca gaaggacata aagtcagcca aaagagcaaa aagatattcg
     1921 accagaccac tcggtaatta attcgttctg ccatctgaaa tatacgatga tggttcaccc
     1981 agatcaccgc aacaaatata aagctgatgg tataagctaa taatgtattt cggatgaccc
     2041 ataaagaatg aaagctagat gtattaggga tcttgatctc taatacaaga actctcaaaa
     2101 caatggctac cactccatca gtaaatgctt ctaatctcga ctttgtcacg atgattcctc
     2161 ctcagatgat tcagcgcttt tattttatca cttacgttat taaataacca tcgttttata
     2221 tagggaattt tctgaaaatt gttgcatatt tttcgaaatt ttgttacttt taaaaaaacc
     2281 gtaaaggagt tatgtatgac aaaaaaatta tcatttaaag actatctttt tataggctcc
     2341 atgcttttcg gtctattttt tggtgctgga aatcttatct ttcccgttca tttgggtcaa
     2401 gaagcaggcg ctgctacctt ttgggcgaat ctaggtttct tggttaccgg tatcggtctt
     2461 cccttcttag gggtgattgc cattggtgta tcgaaaagct caggtgtata tgaattagca
     2521 aaacggataa atcaaacata tgcgatggtt tttaccatct tgctttactt agttatcgga
     2581 ccgttttttg ctttacctcg ccttgcaacc acatctttcg agattggttt agcaccattt
     2641 atcgatccta gcagacagac gctatatcta gcaattttca gtattgtatt ttttgtgctg
     2701 gcttggtggt tttcaagaaa accgacaaag atattagatt atgttggaaa gttcctgaat
     2761 cctgcatttt tggttttatt aggtgctttg cttctccttg cttttttgaa tccactaggt
     2821 tctgtaaatc aagcgcctat tcagccaaat tatcaagagc atgctttttt cacagggttt
     2881 actcaaggat ataacacatt agatgcgctt gctgctttag catttgggat catcattgtc
     2941 acaacaatcc aaaacatggg tgtaacaaaa cctgctgaaa tcgctaaaga cacgatcaaa
     3001 tctggtgcga tcagcattat attgatggga atcatttata ctttgctcgc ttatttaggt
     3061 gctatgagct taggtagctt tgctctaagt gaaaatggcg ggatcacgct ggctcagatt
     3121 gctgatcatt atttaggtac ttatggcagt atcttattag catttatcgt tatattagct
     3181 tgcttgaaga ccggtattgg tttgattaca gcttttgcag aaacattcac agatttgttt
     3241 ccgcaaagaa attacgcatt ctttgttgca cttgctagta tccttccttg tttagcggca
     3301 aacgtaggct tgacgaatat cattcaattt tcgttgcctg ttttgatgtt catctatcca
     3361 ttagcaatga cactgatttt actagtgtta gttggtcctt tgtttaagca gcgtacggct
     3421 gtttatcgaa tgactactta ttttacattg attgcttcga tttttgatgg gttgaacgct
     3481 tgcccagaaa ctatcaaaca aacacctatt gttcaaaatc ttttatatgt tgcggaaagc
     3541 tacttgccgt ttttcaaatt ggggatgggg tggatcgtac cagcagttat cggttttgtt
     3601 atcggactga tttggagttt cgctaagaaa gaagaagtag cagattgata aaagaggttg
     3661 tgaaagagac gttcagcctt gagcaataaa aagtaatttt gaaaaatggc ttctcacatt
     3721 tttgcataaa tttgacttaa taccgagaaa ctgacttttg aacaccgttt attgagaggt
     3781 cgtgaaaaag ccgcttagtt tcaagtatta agaaatattt tgtgaaaatg gcttctcaca
     3841 tttttgcata aatttgactt aataccgaga aactggcttt tgaacaccgt ttattgagcg
     3901 tctataaact gacctgagta ttagagaaac aaaacggcaa agtagctcca tatactttgc
     3961 cgttttgttt tgaactaata ccgaagagaa gctgatcaaa caacatttct tttataatat
     4021 agattttaga catatatatg atataaaaat agttttcgca aaa
//
LOCUS       DASHXG010000120         3887 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.129, whole genome shotgun sequence.
ACCESSION   DASHXG010000120 DASHXG010000000
VERSION     DASHXG010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.129"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(112..342)
                     /locus_tag="U2R59_002776"
                     /pseudo
     CDS             complement(112..342)
                     /locus_tag="U2R59_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
     gene            complement(961..1293)
                     /locus_tag="U2R59_002777"
     CDS             complement(961..1293)
                     /locus_tag="U2R59_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEM8967103.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2140..3180)
                     /locus_tag="U2R59_002778"
     CDS             complement(2140..3180)
                     /locus_tag="U2R59_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEM8967104.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
BASE COUNT         1270 a          696 c          519 g         1402 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaaccattca ttaccttcat catcttcagg tagcaagccg aatccaattg gattatcagt
      181 caatttttga tagtataaat catcctcgtc taatgctaaa acatctaatc ctttacaatt
      241 tccgcctctt ctaaacgtca caaatccttt gtaatcccaa cgttggaaag aaaccttaat
      301 agtatgtgtg cccaatcgta tattcggatc ataatttttc atttgtcatt cctccattac
      361 gtaaatttca ttttctctat gttttatatc aattttttca ctttattcag gactcgttca
      421 tattttatcg tttttcgttt acttaaaaat acataaaaaa tatcgactcg tttatggcgt
      481 ccgaaacgag aaaccctagt agaaatcggt aaatgctcga ttgatccaat gaccaacgtc
      541 ctcgcaagta tctacatgta ctgcagcaca cgacacaatt tcttgtgcgt cctccccatt
      601 acgagaagac ctactcctta ttccatgagt ttgcgtcaaa gcctagatcc cttagtagct
      661 gctcatgatt aatctaggcg ctattctaac ttgtctaact tctaaattcc ctcttgttta
      721 ctctgtgcat attatttaca caaattcatt tcaccactat ccaaacaagg gcatttactc
      781 gattgaccaa ttttttacgt taccaatcgt aaaaacctac cccgtcaccc cccgaaagga
      841 attgttgata gatcaagtct actccttatt tttctagtaa ttctaagttc ttttagaagt
      901 ctcgacaata ttttcaagca agcgaaaaac gataaaatac aagttatgag aatgatcaat
      961 tcagctgatt aaacgcccca tcccttttgc ggtacaacgc aagactccat tttttcttcg
     1021 accaatcagt acaccgtttt ggtcataaac atgtttgatt gttggatata gttcttttaa
     1081 agggatagga tcttttaaaa ttatttgctt ttgtttacca gcgtaataaa tcatttcctc
     1141 tgagactttg tctttctgga ttatatattt cttacactgc acaacggttt tactttggcc
     1201 agttgatagt ttcttcgtga ttttctctgt agcggtacac cgtttaccgt agtgacaaat
     1261 atcttcgaga ctcaaaattc ctgtatatga cataaaataa tccacccact tactttaaat
     1321 atttttaata agtttttctt gttatttttc aaaaatagag aattgatttt cgttcatgac
     1381 aaacaaaaaa gagggaacgc atccaaacat gcgttccctc taatttcagc gttcgtcata
     1441 cggcaaagag ccacacggac atttttataa cattatgctt aggcatagat tcatcgtaat
     1501 atcacgtatt tttaacctta acacagccaa aaaaagtggt atcacttttg aatatctgtt
     1561 atactaaatc cgttgcgggt aataccgtaa cactgaaagg taaacgcatt aagggattaa
     1621 aggttgtctt aatgccacct gtggacgtcg acgaaggtta ccagccttcc gagtctcaca
     1681 gggcctttct tttttttgta ttttcaattg tccaaattta tcgtccaaaa gtgcagaacg
     1741 aaaattaatt catcacaagc gtagcagaca attaaattta aaacaactaa atttatacaa
     1801 aaaaatgtaa gcgaataata ttcgtattgc ctgaaaagaa gtaatatcaa ggtttttagc
     1861 ttttttaaaa aatgaaatta cctctcttcg cgtattatta taactaaaaa acagcaacat
     1921 gcaaacgttt gttctctttt ttgtgttgga aattaattat taactattaa cacttatgac
     1981 gtaaaaagct acgtttgtga tttttatcat aatattttaa ctcataaatt ctattaaaat
     2041 agctatttct ttgtaacatt tgtaatataa ttagaataat aaaaaatttt taattttaat
     2101 gctactccat gaagcaacaa tcaatttgtc agtgaaattt cactctaacc agtctttcgt
     2161 aatagttttt gggaagcttt cagaattcaa acgtttttca cttgatactt tagcagctat
     2221 tggtttttcg ataaaccaat tttttacata gacaaaaatc aggttctgga tattttcaac
     2281 tttttcggtt tttaattttt gataggcttt taacagtgtc gtgtataatt cttgttctgc
     2341 attgacataa taactatcga gttcttcaaa aattattgaa ataccacttt ctgtttcggc
     2401 ttttttcttt gcattatgaa tagtctggac agttttttga gcttcactgt aacttgaaga
     2461 aaatgttttt attaaattta atactcgttc agggataaac gtagcaatgc tgtcgtttgt
     2521 cataattgtc tcaaaattgt ctaacaacaa ttgatcttgt aggcggtctt tttcagtgtc
     2581 tatattgtgt ctattagtgt ctaatatatt attattaagt tctggtatga ttttcatacc
     2641 ctctgattta tcaacgtttt ggcacggtat gattttcata ccctcttgag ccccaaggga
     2701 ttcagcgtct gatttttcgt cgagggtggg tatgattttc ataccctctg atttatcaac
     2761 gttttcccta ttctctctat caaatttttc gagtaagtag atatcatttt ctgagacttt
     2821 taattctgct agatatagtc tattaggatt atttttccct aactgtttgt taaatcccat
     2881 ctgcttttgt aataataaac caaaggattc caactctttt ttgattgcta tcgctttttg
     2941 tttttggcag tttaatacgc tacatagttc atttgtcgta taagtaaaat aaacattacc
     3001 ttcttcatcg atttgccgtt tgctgattgc gatctctaat cttgctttta aaagcatata
     3061 ggcaatctta gttgaatctt tcattttttt gtattcgtca gaaacaataa agacttttgg
     3121 aaattgataa aataattcgt tgtaaactct atccgcctta aaaaaattaa aatcagtcat
     3181 tgtagatcct ctactttcac gttgttttat ttatgtaaaa ttacctactc ttttcgaaaa
     3241 tagcaaagat aaataaaaaa tgcaaacgca ttaaaactgt tttttaatta aatactacct
     3301 aaaatcagaa ataaaatgaa ttatgtacta cctttaaagt cattaagaac tactttaaat
     3361 aaatattatt tataattaaa tactaccaga agaacgtatg aataaaattt agttttaaaa
     3421 ttaaagataa ttaagtacta ccagtgtcaa aacaaaaaat aaattaagaa ctaccttatg
     3481 catataaaac atactaccat tactagtaat atatactacc ttatttcagt agtatatatt
     3541 atattcttct tataagacaa ggctttaggc tagaaaacaa tagattatat actactaaaa
     3601 aatacaataa gtactaccaa tgtcagatat atataataat tatgtactac cattaaaatt
     3661 aacttattta ataagatact actgtgttaa tctgaaaaaa attactttaa agtagttaca
     3721 tactacctgt taaattagat actaccatta atacttaaat tagatactac ctatatttat
     3781 attaagtact accgttctag gaataagata ataaaaaaaa actaccaaat tgcaattaaa
     3841 tactacttaa aatgtaaaaa ataagaacta cccaaattag gtagttc
//
LOCUS       DASHXG010000121         3632 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.130, whole genome shotgun sequence.
ACCESSION   DASHXG010000121 DASHXG010000000
VERSION     DASHXG010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.130"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            5..589
                     /locus_tag="U2R59_002779"
     CDS             5..589
                     /locus_tag="U2R59_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8967105.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(666..1859)
                     /locus_tag="U2R59_002780"
     CDS             complement(666..1859)
                     /locus_tag="U2R59_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEM8967106.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1923..2303
                     /locus_tag="U2R59_002781"
     CDS             1923..2303
                     /locus_tag="U2R59_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEM8967107.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2377..2739
                     /locus_tag="U2R59_002782"
     CDS             2377..2739
                     /locus_tag="U2R59_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967108.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            3437..>3632
                     /locus_tag="U2R59_002783"
     rRNA            3437..>3632
                     /locus_tag="U2R59_002783"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         1232 a          611 c          702 g         1087 t
ORIGIN      
        1 caatatggca ttcccacaac tagatttaaa aagtgaaaaa ggaccaaaag ctgttatcaa
       61 aacaaaccgt ggtgacatta ctgttcaatt attccctgaa ctagcaccga agacggttca
      121 aaatttcatt gaactttcca aaaaaggtta ttatgatggc gtgatttttc accgcgttat
      181 tcctgatttc atgatccaag gcggcgatcc aactggaaca ggaatgggtg gcgaaagtat
      241 ttatggcgaa agttttgaag atgaattcag tcgtgaactg ttcaaccttc gcggagcttt
      301 atctatggca aattcaggtc caaacacaaa cggaagccaa ttctttattg taaataacac
      361 aaatgtgcca gctaatatgc ttggacaact agaaggtgct ggattcccat cagaaatcat
      421 tgaagcgtat aaaggtggcg gaactccttg gctagatttc cgacatacag tctttggaca
      481 tgtactagaa gggatggaca cagtagatga aatcgcaaat gtacaacgtg gtccacaaga
      541 ccgacctgta catgatgtag tgattgaaac aattgaaatt tcagaatagt ttggtatggt
      601 acggagtaat tatgaaaaag gacgaaacct agtaaggtct cgtcctttta ttttgaataa
      661 atgatttaat cgattgtctc taaagcatac ttgattcgat taagtccttc cagtaaagtt
      721 tcttctggac aagcaatatt caagcgcata tgcccatgac cggaaggacc aaacgtgatg
      781 ccaggattta atacgacttt tcctttccga acaagagtgt tctccaattc ttggtcgtct
      841 gaaatatagg cggtaaaatc taaccacatt aagtaagttc cttcagggtt cattattctc
      901 actttcggaa gatactgttc aaaaaactga ttaactgttt gaacattttt ttctagataa
      961 ggaatcagtt ggcttaacca ttctccaccc gtctcataag ccgcttgggt tccaatcagt
     1021 ccaaaagtgt tgatttcgtg ctgttggttc atcactaaat gtttttcaaa atcagctttc
     1081 atctctggat ttttgataaa taccattgaa tttttgattg cagctagatt gaaagtcttg
     1141 gttgcggaag taaaagcaac tagtagatca tctaaattag gatcaatcgt tagcatggaa
     1201 gtaaatgtat gatcgaataa agttaaatct tgatggatct cgtcactaaa cagaatcact
     1261 tgatgtttta aacacaattc gcttaactgt ttcaattctt ctttgctcca aacacgccct
     1321 ccaggattgt gaggattgca taaaatcatt gcttttacat tgttttcttc gatttttttc
     1381 tccatgtcag acaagtccat gatgaaatga ttattttttt ctagcaaaga gcttcgaacg
     1441 atgtgacgtt gatttgtttc tataatagag gaaaatggag gataaactgg gtcatgaatc
     1501 aaaatagaat cgcctggttt tgtaaaagtt tgtactgctg cagctaaact ggttaacaca
     1561 ccacttgtaa aaacgatatt ttctttcgtc aactccacag catggtgttg gcgttcccaa
     1621 tgaatgatag cctgatatag tttatcagac agagtggcat aaccaaagat tccatgtttg
     1681 atgtattcac taaacgcttt agctacccca ccgggagaca agaagtccat atctgctacc
     1741 cacaaaggaa gtaagtcatc catttgatat gtctcagcaa ttgcgtccca ttttacactt
     1801 tctgtatctt ttcttgaaat ctgtttatca aattcgatca tcttaagacc tccagtcatt
     1861 ttcgtcgctt ctttttttga gctatttaca gtataatgat aaatgcgaag agagggaagt
     1921 agatgactta taaaattgga caaataattg aaggaaaagt gacagggata cagccttatg
     1981 gcgcattcgt ttctcttgat aacgagacgc aaggacttat tcatgtttca gaagtacaat
     2041 ccggttatac gaaaaatatc cattcattgt taaaagtcgg acagccagta acagttcaga
     2101 tcatcgacat tgatgaatat tccaaaaaaa tcagtttatc tttaagaacg ttagaaaaaa
     2161 caaatccagc tgttccatat cgcagaaaaa ggtatttcac gaataaaaat cgtaagatcg
     2221 gatttaccac tattgcggag cagttaccta tttggataga agaagcatta tctgaactag
     2281 aacggaaaga aaataagaaa taaaaagtgt attttttctg aaaatgtgct agaattttta
     2341 tgtaagccat agaacaagtt gatcgaggtg gaaattttgg caagcaaaag agttgctggt
     2401 acaattatgt tgcatttgga ggatggtact aaaaaatttt tggtccattc aattgatgac
     2461 aagttggaat ttgcgttagc ggaactttct gaaggaaaga ctggtttagc gaatatactt
     2521 aatttcttaa aagaaatagt tcatatcgat gttagcaaga ttagtttgat ggaattgaca
     2581 aatacacata ttaaagagga aaatgttccg ttgtttgtct ttgaaactga acaaaagaat
     2641 caaagagaag aattaggcga aggatatatt tgggaagaac caggtcaaat gcgctctgtt
     2701 cttggaactt acgaagtaga gggagtgcct ttcttctaaa atacagatta agcgaacaaa
     2761 gaagtttgaa tttttttcaa acttcttttt ttattgtttg gtccaaaaaa tacaatgaaa
     2821 tgttctgcta aagatagttt tttagtgcat tttattttca aaatatgttg aaaacggttg
     2881 tataacgaat aataataatt gatcgaaaaa tcatttcaca aagtaatgct taatttatag
     2941 ttgaccaagg aagaaataca tgataaattt aacagcgttg attctgaagt ggatgttata
     3001 tcacatttct aaaaaattta aaaaatagtt attgacatgt tactaacgac atgataagat
     3061 aactgagtcg ttaaaaaaga accacttgcg aagcttgatt ctatcgaaaa aaacttcaaa
     3121 aaagttcttg acaaataaca aacgataagt tatgataaat gagttgctga aagatttcga
     3181 aaaacgaaat cgaaaaaaac ttttaaaaaa gagttgacaa tcgcttgtct ctctgatatg
     3241 atataaaagt tgctacggca gccaaaaacg aatcgggaaa cactctcgat gaagtagacc
     3301 tttgaaaact gaacaaagta agacaaacca aatgtgtagg gcgtcttgat tcaattcaag
     3361 acaacaaaca tttttaacaa gcaagcaata tgctagcaaa caaattgagc ttaacaatcg
     3421 caagattgtt cgaacttttt atgagagttt gatcctggct caggacgaac gctggcggcg
     3481 tgcctaatac atgcaagtcg aacgcttctt tttccaccgg agcttgctcc accggaaaaa
     3541 gaggagtggc gaacgggtga gtaacacgtg ggtaacctgc ccatcagaag gggataacac
     3601 ttggaaacag gtgctaatac cgtataacaa tc
//
LOCUS       DASHXG010000122         3600 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.131, whole genome shotgun sequence.
ACCESSION   DASHXG010000122 DASHXG010000000
VERSION     DASHXG010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.131"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            578..886
                     /locus_tag="U2R59_002784"
     CDS             578..886
                     /locus_tag="U2R59_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967109.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            888..1310
                     /locus_tag="U2R59_002785"
     CDS             888..1310
                     /locus_tag="U2R59_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967110.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            1330..2919
                     /locus_tag="U2R59_002786"
     CDS             1330..2919
                     /locus_tag="U2R59_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967111.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            2931..3266
                     /locus_tag="U2R59_002787"
     CDS             2931..3266
                     /locus_tag="U2R59_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967112.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            3412..>3600
                     /locus_tag="U2R59_002788"
     CDS             3412..>3600
                     /locus_tag="U2R59_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967113.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYPF"
BASE COUNT         1438 a          523 c          704 g          935 t
ORIGIN      
        1 attcagatca tttgaagctc tatatgtagc tgctaaaaaa tattttacag ctgataacaa
       61 ataaaaaaca ggagtatttt atgtgaaaaa agtatataaa aaatgcttat gaatcagcta
      121 tatcacctta accatttgtt aatgagatgg gagaaaacat taaccacgat tctaacgcaa
      181 acatcaagca cataaaacat ttaacactcc tcctttctgg ctgaagattt caaccaaaca
      241 ggaagacagc gtatcaatta tagcatacac tttttcttaa attcattttt catatgacaa
      301 aatatttcct tctaatcgac aaagttagaa ggatttttta ttgtctaaat acacaaataa
      361 ccttaattta taaagagcat aaggaaacgt gggaacactt tttaaaaaaa gtgttccaat
      421 aggctgtgcc tattacgttt ctcaaaaata attgtgggaa caaaatattt aaaaatagga
      481 tagtgaaagg atagcaaagg atagtaaaag gatagaagca ggatagcgaa aaggataggc
      541 tccttttcgc tatccttttt aaattggagg aattaatatg gaagtaagaa taagaaatgt
      601 agatgagaaa atcgtaagag aaattgatcg aagatgtgac gaactaagta accgaacggg
      661 taataaatgg agtcgtaacg attatttaaa gctactcgtt gaaaatgatt ttgatcgtcc
      721 tttgatggaa tataaacaag ataaatttga tcaattatta aatcagttaa tagataaatt
      781 ttcttttgtt caaagtcata atacaaaagt attagaagaa tatatttgtc agaataatca
      841 aattatcgaa cttttaattg aacaaagtag aggaggagaa gtttaacatg gccaaagtta
      901 tagacaagca tatttatttt tatgaaacac atatagatgt tctagatgaa attattgcaa
      961 ctcatgcaga ggttaaaaac tatagtgaag ccgttcggtt tctatgtatg aattatgatt
     1021 cagaagtgga gaaaaaagta aattccaatc aagcaaagtt gaatgcaatg ggaaaagaaa
     1081 tttctatttt aaccgaaatg gtttcagagt ttgcggatct ccatttgaaa gatacaggga
     1141 ttttaattgg tacaaattca actgtttacc aagaagcaaa agagcgtgtg gaaggcaaga
     1201 taaaagcaaa tcaaacgaag aaatattctc ctaagataaa gaaaacaata agcgaatcag
     1261 tgactacaaa aagtgaagta tttgatccaa caaggttctt aaaacgataa aaattagaag
     1321 gagaatgtga tgagtaaatc acctgcagtc attctcactt gtcaatttac cttgcccaat
     1381 aaaaaatctt tttcaacata cattgattat atgacaagag aaaaagcgct ggaagaaaag
     1441 gaacgacgta cgcccgagga agaacaggaa ctgcgtctaa tcaagaatgc tttagaggat
     1501 ttttatattc ctgaaggaga aactttttcg gagagtaaga cgggtaaaga attcagcgaa
     1561 acgtcgaatg aagcgcaatc gttgatgaaa catggaatca attttgacaa gttagaagaa
     1621 caagatttta ccaaatatct ttcttatatg acacgtcact atgcgttaga acaaaagaaa
     1681 gtactgacgc atagtgaaca aaaagaatac caacgcttga accaagcaat aaaaaaatat
     1741 caaacagagc cacacaaaaa agcttcagga aatcttcctg gagttttttc tatggcttca
     1801 gacgaagtga aaggaagtga tctgaaggag atcaagcaaa ccttccaaag aggacaacaa
     1861 aaaggctcaa tcatttatca agatgttgtc tctcatgatc attcgtatct tgaaaaaata
     1921 ggattgtacg atcccaaaac agatacttta gatgaagaag gtttaaaagc agctggaaga
     1981 aaaatgatgg agacattgtt cgagaaagag caactgaatg aaacaggcta ctggatggca
     2041 acgattcacc gaaataccaa acatatccat attcattttg cagttgttga aaaaaaaaat
     2101 acgcgtaaac catacactga gattgaaaat ggtgtgagtt atatcgtacc gaaagggaag
     2161 agaaggcaag caacattaga cgaaatgaag actaattatg tacatgagtt agaacgtttt
     2221 tcttatgaaa aaaatcgaat gggtatggag aaacgaaatt tattgacacg gaaaagtgat
     2281 ttgcgtaaca ccttaaccaa agtagtgaaa gagccagtac gttatgatcg acacgcaatg
     2341 agcttattaa ctgaagtata taaaaactta cctaaaaagc gttcggaatg gcattacggg
     2401 gatgaaaatc gaaccaaact ttcaccatac acaagagaga aactcgatga gttaacccaa
     2461 tatgtgttaa caaaagaacc tggatatcaa gaatatatac agatttcaaa agcattgaaa
     2521 gaagaagcaa aaagtcttta tggggaaagc aagagagaat caaaggatgc agaaaaaaat
     2581 gctctctttg atttaaaaaa gcgcacagga aatgccattc taacagaact gaagaaacag
     2641 gatagtcaaa taaaaccttt aatagaaagg atggatcaga tgcaatctat ttacaatgaa
     2701 cgatcctttc gaacacttaa acagttgcca acgaatgaat acaaatatag ttacgaagaa
     2761 ttcatgaagc gcaggaaaca attccaacaa agagttgtca cgcaacggag tttgcgtcaa
     2821 ttaaatcgaa cgattaatgc ccatgaagaa aaataccacg caagtaaagc atacgaagag
     2881 caacaacgaa gaattcaaat ggaacaagaa agacagtagg aggaatagca atgaaacaat
     2941 atttagatca atggaaagtt atagaaggat cattaagaga agaacgaatc gaacaacttc
     3001 ccgattgttt agaaaaagag catttgtttc agataagaga aatgttgaga aacgaacagt
     3061 ttgatccaaa tcaattttta gtcgttgagt actcagctac tggtgtgtac tgttgtaatc
     3121 atgtgaaggg tgaaaaatat tttatcattc aagaatatga gggcaagtta gcgccttatt
     3181 atactacttg ggaaatgaat gaagagggga tcaataactt cccgtgtaaa agcattgaag
     3241 agtctatttc actcacagaa tgttagttgt taagtgaata aaagaagtaa aagagtcctg
     3301 aacgtaattg tccaggactc tttttttcaa tgaattgttt tccgccaatt caatgagtgg
     3361 tgcgatttgc gactacatta tatcaaaaga aagagaaggg aggaagaaga aatggcttat
     3421 tcaacgattg gagttgttgt tgaaaaaagc agagacaatc tcgtttttgt gacagaaatt
     3481 caaacgggca gagcttttgt cgtcacagac aaagcggcaa aagcgtatca aagtggcgat
     3541 attttaacgt taaatctgac tacgaagacg ttcgtcgatg cggcagaaga ttatccattt
//
LOCUS       DASHXG010000123         3205 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.132, whole genome shotgun sequence.
ACCESSION   DASHXG010000123 DASHXG010000000
VERSION     DASHXG010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.132"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            406..501
                     /locus_tag="U2R59_002789"
     CDS             406..501
                     /locus_tag="U2R59_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEM8967114.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(803..1048)
                     /locus_tag="U2R59_002790"
     CDS             complement(803..1048)
                     /locus_tag="U2R59_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967115.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1394..1678
                     /locus_tag="U2R59_002791"
     CDS             1394..1678
                     /locus_tag="U2R59_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967116.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1681..2097
                     /locus_tag="U2R59_002792"
     CDS             1681..2097
                     /locus_tag="U2R59_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967117.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(2234..2953)
                     /locus_tag="U2R59_002793"
     CDS             complement(2234..2953)
                     /locus_tag="U2R59_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEM8967118.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
BASE COUNT         1070 a          597 c          499 g         1039 t
ORIGIN      
        1 ataaataaaa taaacgcgcg cgcgcgagca aaatttcccg ccaaaaaatc acccactttt
       61 taaaataaac aggttcgcgc atgatattaa actgccaatc tagctcccta tggtcgctgt
      121 aagaaggagt gatcgctacg ctctcacatt ttacttgcag cagtcgcctt taggctcctt
      181 cgccaaaaat aattcattag ggactccttt gtggcgtcct gagagctcgt ctaagccgtt
      241 ctaagacaag attcgataaa aactatgtcc ttcgttctaa agcgccttac aggcggtcag
      301 ggcaagccct aacaacccca aggcaataaa aaacttaggc ttatttttgc ttttttattg
      361 tataattgat tgtcgcctat ccgacagtct tgcgactgga aggaggtgtg tttcgtgttc
      421 actaacttta tttgctccct tcttgttggg cttttaagcg ctttgttcag ttactggttg
      481 aataaccgaa acaagaagta aaacttaatt aaggcgactc agcccacaaa aaaagcccca
      541 gagaatccga cctctctggg gctttcgtgt gtttcgtgtt cacttatttg caatcaaatt
      601 ataacagaaa taaatattta tttcaaaaat atcctacaaa agtctaaaat ccgtaattat
      661 ttcttatatg caacatttac aaataaagtc gctctgagag ctcgtatttt tcgatttaag
      721 acgttttatt tagtttttgg tgtatttcat tggtccaagc taaaaaactc ttagaagcga
      781 ttttagagcc atttaaaccc acttaattat attctccatg aaattcgctc catgcgtcaa
      841 aagctgcgtc tgaaattccg ccgtcttcgt tcactagttg cattaatttt tccaacgatc
      901 gttttctttc gggtgtcata tttttatatt ccaacaattt ttcgtctgtt aaatcgaact
      961 tgattgcttg aattgcttgc tctaattttt ctaagttttg aaaatattcg taaggaaatt
     1021 tttccatttt ttctttctcc agtctcacaa tttttctaga aataaaatca cttctttgcc
     1081 gtctatactc tcaaaaaaaa atgtcgtttg aaaaactaaa taaatttttg atcgtgcatt
     1141 tttaaatttg gttatcgatt acacgtgcag cactcccccc cgaattttaa agagcataag
     1201 gaaacgtgta cccactttct aaaaaaagtg ggtagatagg ctgtgcctat cacgtttctc
     1261 agaaaaaaat ttgatatcac tttttcgcca tcgtgggtag cttatgtata gcattttggc
     1321 aaaaaacagc tatacaaata tagtatttgt atggtataca taaattatac ataattgcaa
     1381 aaggagattt tttatggaca ttttagttcg gaatattgat ccaaagtttg ttgcaacaat
     1441 agacaaacgt tgccaagaac tcacgaataa aacaggagaa aaatggagtc gaaataaata
     1501 tctaaaagtt ttaatcgaaa gtgattttga ccgtcaactt acgacttaca aaaaagacca
     1561 attcgattta ttgctcgata aatttattgc tatccaaaca gaaaatactc aaatattaag
     1621 cgagtatgtc tacacaaata atcaaatcat tgaaatgctt atcggaggaa tgatataacc
     1681 atgagaaaaa cttctgtcca aaaacatgtt actttgtacc ctagtcatgt tgacgtttta
     1741 gattccatca tcgaaaaaaa tccagatatc aataactact cggaagccat tcgcttttta
     1801 tgtatgagtt atgaacccga taccaacacg accactacca gcaatcaggc aaaactaaat
     1861 gctatgggaa aagaaatttc catcatgact gaaatcatcg cagaatttgc tgatttatat
     1921 ctaaaagata caggcgttct tattggcaca aattctaaag tatatcaaga agtgaaagaa
     1981 aaaatcgaag ctaaactaaa tccatcaaat cgaaatcgac caaagaatca tcaaaaagaa
     2041 accagtcaaa cagtcacttc tagaaatttc gacccaacaa attttctaaa acgataaaaa
     2101 acagatagga gttattccta tctgtttttt atttagaagc cccatacaat atgctagaat
     2161 gtactagcaa tcttagtcgg ttgtaaggga cttgtctact tgcttaatgt aaggggggcg
     2221 agttcttttt tatttattct tctaaccagt tacgcagaga aatctttggc aaatctgacg
     2281 ttaggcttga aaaagtaaat tctaatttgg cgattttatt gccctttttt gcttttattt
     2341 ttgtgacttt aagatcattg aagtattttt ttagttctcg taatgcagga tttaatactt
     2401 tttgatcaat gttacccatt tgatagtatt ctgggatatc cattaagctc ctaaactctt
     2461 caatacgaac tacataataa ccagtagaac ggtactgcat aagcagtcgg aatagagttt
     2521 ttgcatacgt agaacgcaac gacgtgaaag cagataattc aaatctacta aattcagctg
     2581 ttaaaccatt aataatatat tctaggtccg gattaacact gacttcaaca aacttttttg
     2641 ttttattgat ttcaaaacca gtaaacaaaa caaagtagcg aatagaatcc tcatcttcag
     2701 tacggtaagt aagattaagc atatctttat agagcttttc taaatcaccg acaaaggctt
     2761 ttgtagcagt catcttataa tcacttaact cttttaattc ctcgaaagaa aatctaactt
     2821 ttttcaaacc acgatctttc atacgagcgc ataatgcaaa aaataaatcc atctgcttag
     2881 cattgaaatt tttcagcggt actaaattca attcattttg atatttgact gttaattccg
     2941 ttttttcatc cattcctttc ttcccccctt acaaataaat aataaccttt aacaaccaac
     3001 tcgtaaatag gttggttgtt attatacaaa aggatattag tactcagata aaaagttgtt
     3061 agtactcaga taaaaagttg ttagtactca gataaaaagt tgttagtact cagataaaaa
     3121 gttgttagta cccttctgta tccgttggga gagtaaggct caactgcccc ctaaaaaggg
     3181 ttctaaaaaa tctttaaaaa ataaa
//
LOCUS       DASHXG010000124         3166 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.133, whole genome shotgun sequence.
ACCESSION   DASHXG010000124 DASHXG010000000
VERSION     DASHXG010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.133"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..433)
                     /locus_tag="U2R59_002794"
     CDS             complement(<1..433)
                     /locus_tag="U2R59_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967119.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
     gene            complement(992..1309)
                     /locus_tag="U2R59_002795"
     CDS             complement(992..1309)
                     /locus_tag="U2R59_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEM8967120.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(1310..1564)
                     /locus_tag="U2R59_002796"
     CDS             complement(1310..1564)
                     /locus_tag="U2R59_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEM8967121.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1824..2042)
                     /locus_tag="U2R59_002797"
                     /pseudo
     CDS             complement(1824..2042)
                     /locus_tag="U2R59_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2602..2688)
                     /locus_tag="U2R59_002798"
                     /pseudo
     CDS             complement(2602..2688)
                     /locus_tag="U2R59_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT         1060 a          549 c          437 g         1120 t
ORIGIN      
        1 tcatatttcc ttgattacct gaggcaatga aagacttatc tacttgaatt agggtgaaat
       61 tctcattcaa atatggtagt aaaattaata tatgtgaaaa tcgaatcttg agatagctat
      121 tccccttgag atattcactg atacttctac tcaaatcatt taaattttta taattatttg
      181 tacggaacgt atatatatca acatcagttt tctttacatg agaacttatt ctaaaatgaa
      241 aaagcctact ctcagaaaga attgaaaaat agatactttc agtagatact gaagattgaa
      301 caaaattaaa cttgtatcct tcaggcatag cacttttaac agtctgctgc attaactcgg
      361 ataatctttt gaaagtagta atatattttt taccagcaaa ccatacatat cttttttcat
      421 taagtatgtt cactatctct cctccattaa ttatatttag catcaaatag ttattgtacc
      481 tatattttat cccattcctt ttaaaacaag aatacgtaca aagtaaaatg ttgtaaatag
      541 tctagcaggg atgtatattt tcatgtacca acataatatt taagaagttt cccatagata
      601 tattggactt cctcttttaa aacacaaaaa taaatactac cttatttagg tagtatttat
      661 taaaagttac gtcaattttg attaaaaata tactacttga acctctcatg agtaaagtca
      721 cgaaattttt gggaatagag cgtacttgat atcttatttt ttcactaata gcagtgtctc
      781 ttattcacca agcgatcccc gtagttccta cggttcttaa tttttctcta gactaatgat
      841 tgtatcttta gaccttcggc cataacatgg agcaaaataa aaaggtacta agtcttatat
      901 atcaatcttc gagtaaccga cggttaacaa ccatatcgag cggcattaat cacccacctg
      961 tagaggatga gcgacttttg cctaattatt gttaaaagcc tagtttcatt tgtttagatt
     1021 ggaaaatacg tcctacaagt atctcttttt tttcatggtc gatccgataa aataaggcat
     1081 agcttttgcc gatcacgatc cgatatgttg ggatatccat tccatagatt tcggaaactt
     1141 cctcatgcat agttggaaaa tttttggtta gttctaaagc cttctggatc gcacctacaa
     1201 atctttttat gctggctgga gaaagagcaa gctcattttc ccattcttct attatcgttt
     1261 caaggctggt ctggaaactt ttagaataaa ctagcgtgta ctctttcatc tattcactcc
     1321 agccgtattt tccgaaagct tttaccattt caatttctga aactgttaaa cctttctcaa
     1381 agtcttggaa actttcttca atcaatttgc gatcgtgttc ttttgctatt tgagtagtat
     1441 ctaatatgaa taagttgcct tcttgtttgg cttggatagt gtctccgctt tttaatccaa
     1501 gagagcttgg aaggatcact cccacgctat tgccgatctt tctaaccttt agttcttttc
     1561 ccatgttatc acacttcttt tagtttttga taaataaatt ataacatgtt ataacgacaa
     1621 ttgccaacgg tgtttcttaa gggattccac tccatattat tattggacaa aataagccac
     1681 ttagaacgct gaaaacatat acaaacgata tcaaaatacg agtgaactac tcaccataca
     1741 cttccgttaa catccattta agtaggtatt tttattatat atagatttaa catatgtcgg
     1801 tcggttgatt gatatagcta aagttataac tcaaccgaag ccgattcatc tacacgaata
     1861 aagttgcgag tgttctcggc taattcataa aaattgttat gtgttccata tagcaatact
     1921 ggaataactt tattttcttg aatctcataa gcaactctat acacggtgac cgcatactta
     1981 aatccattag accaattacc tgataaacct ccagtttttt gctcttactt aaatggatca
     2041 atagcaattt catcacaaac ctatagagga tgagtgactt ctgcctaatt acgttaaaaa
     2101 atattgaaag taactctatg tagcaaaaaa tatctagaat ttcatttcct caaaactgat
     2161 cgatattgta tctaaaaata tatactacct aaaataggta gtatatatta aaatatgtgc
     2221 ttttgttaga aaaatcaata cataaattat catatctgta tatgtcattt aggtatttca
     2281 gttatgttat aatagttttg ctgtctgcta ccccggccta atctggcaag gggaggagga
     2341 gatataatga aatacctttt tgattttgtt tttgcaatca agccatttgc agaggtaact
     2401 gcacactaca tctgcaagtg gcttgattgc aaaattgcca aaaaagacag taagcctacc
     2461 agttaattct ataatataga aacgtaaaaa aaaccccatc agcctacacg ctgatggggt
     2521 ttgatgatat aatgaaatac ctctttgtta ctcataatta taccataatt agtcacgaat
     2581 gcaaccaata gaaaaaacta cttagaacgg tagatcatcg ctaataacaa tgcattgtcc
     2641 accaaatgga ttttgtgaag cattaaatac attgttatta attgtcgctg tttttaacta
     2701 ggcctctccc cttctattat aaaagaagat atatattatt tcttaattac ctactacctt
     2761 aaaccaaaat ttaagtacta cctaatttaa gtagtactta aataatctaa aaaatagtta
     2821 tcccaattgt tatgctttta taatacgatt atttgtaaca aaatgaatat tatataatta
     2881 aacactacca tatttaggta gtgtttaatt attagcaaaa caaaaaatat ttattctatt
     2941 ctcttaactt caactaagtt atgctgcaca cctttatata aatcatatgc aactcattag
     3001 ctagacaaac tacaagcatg tagttttatc tgttaattat gtactaccta aataaagtag
     3061 tttataatta acaggtatat atatttaaaa atttaagatt aattttttta tgacttgtac
     3121 aaatttatct gatattctct tattaagaac tacctaattt gggtag
//
LOCUS       DASHXG010000125         3048 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.134, whole genome shotgun sequence.
ACCESSION   DASHXG010000125 DASHXG010000000
VERSION     DASHXG010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.134"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            14..175
                     /locus_tag="U2R59_002799"
     CDS             14..175
                     /locus_tag="U2R59_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967122.1"
                     /translation="MKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            172..1476
                     /locus_tag="U2R59_002800"
     CDS             172..1476
                     /locus_tag="U2R59_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8967123.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            1572..2441
                     /locus_tag="U2R59_002801"
     CDS             1572..2441
                     /locus_tag="U2R59_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8967124.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(2553..2873)
                     /locus_tag="U2R59_002802"
     CDS             complement(2553..2873)
                     /locus_tag="U2R59_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HEM8967125.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
BASE COUNT         1015 a          574 c          614 g          845 t
ORIGIN      
        1 tgaagatgaa aaattgaaaa aaagacaaga attacttgaa gaagtgtata cggaacgttt
       61 tggaacaaaa gaagagagag aaacggtccg tttttattct gtctccgaag agaaaaatct
      121 agatacgaca ttcattgcag atttgtataa agaaaatggg gtggaactga aatgatctca
      181 atcacccata caggtaattt attcttagat acttgtttgt ctattatgta tttttttctc
      241 gtttcttatc cgattttagg cggatttgta tggtttattg gtgtctggtg ttatgtgttt
      301 ttatacaaac ataagcaaaa agaatgggta gatgttccct tgagtgtcga accgttcatc
      361 acgatcatgg tgccagccca taatgaagaa attgtgatcg aagatacaat cgagtatttg
      421 atgacgaaat tgaattatca caactatgag gtattagtga cagacgatgg ttcaacggac
      481 caaacaccag aaatattagc tagactgatg aaaaaatacg ctaatcttcg tgtggttcgg
      541 atcgaaaaaa ataaaggaaa agcccacgcg tttaatatcg gacttgcctt tgcaaaaggg
      601 aaattgattt taagcaatga tgcagacacg gtaccggagc cagatgcact gattaggtat
      661 gtgaattatt tcattcgccc tggtgcaaga catattgctg cggtcactgc aaatatggat
      721 gtccaaaatc gtaccaaatt gattgcaaaa tctcaaacgg ttgaattctc aagtatcgtg
      781 ggcatcatta aacgaacaca gtcagctgtt ttcggtggtc tttatgcgta cagtggagca
      841 aatacgatgt atcgaaaaga agccttgatc gatgtgggcg gattcagaca agatcgagcg
      901 acagaagaca tcagtattgc ttgggatcat cagttaaatg actggttatc tgtttttgct
      961 cctgagatta tctttttcat ggaagtacct gtgacgttga agatgctata tcgacacaga
     1021 aaacgttggg caaaaggtgg aacagaagtc tggctgacga atttcaaaaa agtgatgctc
     1081 catcctttta aacatattgg aagaacgatc atcttcattg atcaaacatt gagtattgtc
     1141 tggtcaatat tcttttgtat ttccgtagtt ctttttgctg gattaatcgg gcattatgta
     1201 tatcaaggaa actacgaaca gatttatatt acttttacat tcagttttgt gttcatctgc
     1261 tttgaaatgg tcgcaggatt tttccagttg ctagcttcgc tgattgtaga tgatcgacga
     1321 agaaaattga aataccttct tttcgcacca ctatatatgc ttttgttctg gatagtgaac
     1381 gcgataacga tcgtgacgac tttcattcca gcagtcaaaa cgattttagg ttatggaagc
     1441 gggacatgga aaagcccgga acgtacaaaa aaataaaaga tgcaccgttt tttagacaaa
     1501 cagcctgttg tgtttatggt tcttccaaac atttttgctt ataataagaa attagttaaa
     1561 aagtagtaag gatgggaaaa gtgatgaaaa aaagaatgaa gccgttaatc tggccaattg
     1621 ctgtttccag tattttctta ttgggacaga cagcttttgc ggaaacttct gaacctgctc
     1681 aaacagaacc ttcaacaacc ataagctctt ctggtgctga aaacggtgcc tcggaaacag
     1741 aaatgacttc caatgtaccg acagataatt caggagaaac gatttcatct tcagaagata
     1801 catcaataaa tagttctacc tcttctgacc aaatcgatca tttgcaagac ttggaaaata
     1861 aaagaaaaga actcgaagaa gcattagaag ctgcaaaaaa caaattgaaa gaagaccaag
     1921 cagcaatcga tcaagattta gctgatctta aaaataaagt gggaaatgac cgtgcacaac
     1981 ttgagaaaaa gcttgccgaa gcgaaagcaa aagcggaagc tgtccaaaca gatcttgacg
     2041 ggaagatcca acaagcaaaa gaattcaatc agcaattaaa tcaggttgct caaacagctt
     2101 ctggaaagct aagtcaaact caagcggata tcacagcggc cagtcaagca atccacggaa
     2161 agatcagcga agcacaaaca gttgctaatg attttgaagc aaaaaaagct gacttagcag
     2221 ctagtttcca acgaataaaa gatattttgc attcggcagg agaaaaatca gtgacctctg
     2281 gaagcacgac agaaacagtt cagcaaacga cagagccatc caaatcaaca agtcagactt
     2341 tgccaaaaac aaatgaaaaa acagcttctg tcagttattc cttagcaggg gcgggtgtgt
     2401 tagtcgcagc agcttacgga atcatccgca aaaagaaata aaaaagagag gatgggaagg
     2461 tagagtacct cgaagttaga ctgaaaaatc taattcttga gtgccactac atgtcccatc
     2521 tctctttagt tattaaaaca gatgtcccct acttatctcg tggagacagc tgttccacta
     2581 catgtgacca tcagcatgcc attgtcgctg cctaatactt catagtccat ttttacgcca
     2641 atgatcgcat cagctcctaa tgcttttgca cgttcggcca tttcggcaag tgcttcttct
     2701 cttgcaccca ttagttcgtt ttcatagctt tttgagcggc cgccaaagat atttcgcaac
     2761 cccgcctcca agtctttaaa tgcatggatc ccagtaatga cctcaccaaa aacgatccct
     2821 ttataagcta ctacggcttt tccctctaca ctgttcgttg ttgttgtaat cattcgatca
     2881 ctcctctctt ttaattaaag tataacaaac ttcaagaagc actacacata ttttcccaaa
     2941 attagaaatc gccgattgta aaattaagct agacaactaa aaaagtcatt tgtgctacac
     3001 tcaaaatagt tccgtcgaaa gaattataag gagtgagtac aaatgacc
//
LOCUS       DASHXG010000126         2975 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.138, whole genome shotgun sequence.
ACCESSION   DASHXG010000126 DASHXG010000000
VERSION     DASHXG010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.138"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            50..1438
                     /locus_tag="U2R59_002803"
     CDS             50..1438
                     /locus_tag="U2R59_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HEM8967126.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>2975
                     /locus_tag="U2R59_002804"
     CDS             1776..>2975
                     /locus_tag="U2R59_002804"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEM8967127.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMMARMNMILH
                     GVPIANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVL
                     APKSKADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGL
                     PANIFFNT"
BASE COUNT         1090 a          462 c          541 g          882 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgatgg
     2581 cgcgtatgaa catgattttg catggggttc ccattgccaa ccaacacttg cataatgcgg
     2641 ataccttgga tcaagactgg ccaacagaag agccaacgaa cttcgatggg gtgctcatga
     2701 acccaccgta ttctgcaaaa tggtcggctg ataaaggctt cttagatgac ccacgcttct
     2761 ctgcctatgg cgtattagcc cctaaatcaa aagcggactt tgctttctta ttacatggct
     2821 actatcattt gaaagatacg ggcgtcatgg ccattgtttt gccacatggg gtgctcttta
     2881 gagggggcgc agaagggaag atacgcaaag ccttgttaga aaatggtgcc attgacaccg
     2941 tcattggctt acctgctaac atcttcttta atacg
//
LOCUS       DASHXG010000127         2929 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.139, whole genome shotgun sequence.
ACCESSION   DASHXG010000127 DASHXG010000000
VERSION     DASHXG010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.139"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..493
                     /locus_tag="U2R59_002805"
     CDS             <1..493
                     /locus_tag="U2R59_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HEM8967128.1"
                     /translation="LVSIHQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGD
                     ILTHFDYGLRRFTFTAEEFAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYR
                     YAVPLYQSVGGKLFTLGSDAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPL
                     PIL"
     gene            526..909
                     /locus_tag="U2R59_002806"
     CDS             526..909
                     /locus_tag="U2R59_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEM8967129.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            985..1116
                     /locus_tag="U2R59_002807"
     CDS             985..1116
                     /locus_tag="U2R59_002807"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8967130.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            1085..1321
                     /locus_tag="U2R59_002808"
     CDS             1085..1321
                     /locus_tag="U2R59_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEM8967131.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1399..2370)
                     /locus_tag="U2R59_002809"
     CDS             complement(1399..2370)
                     /locus_tag="U2R59_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEM8967132.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT          859 a          613 c          609 g          848 t
ORIGIN      
        1 gctggtaagt attcatcaaa atggccgctt tgattatatg gacgatgtgg ttttaaccaa
       61 agatcccatt caaactacca aggaatattt tgatcagatg ttgcaggtct tgacggattt
      121 tccagaagga gatattttga ctcactttga ttatggatta cgccgcttca ccttcacagc
      181 ggaagaattc gcggagcatt ttgaggctca gctgctaacg attttcaaaa aggttgttga
      241 acgagaattg gcgatggagt taaatgccaa gagcttcttg aaatacggca acgaagacct
      301 ttaccgttat gccgttcctt tgtatcaaag tgtcggcgga aagctcttta ccttaggctc
      361 ggatgctcat gttgccgaag attatcagct gggctttaaa aaaatgagtc agctgttggc
      421 agactgtcag gtagaaaagt tgctagtcat tcaaggaaaa gaacgccgcc tgacgccgct
      481 gccgattttg tgattcctat ataatagaag aaagtggtga aaaaaatgag caacctgtgg
      541 gactacaatc aagaggcacc catccattat ttaattgcgc gacattggga tgcgttgaaa
      601 attgaggcgg tttgccgatc cttgttagca gccgttccaa aacaacaact ggaaaatttt
      661 ttggtggctg acagcttgca gcgggaaaaa gttcaggctt attttgcagc ctttaaagat
      721 cagcctttgg aatatttgca tgcgcagttt catctttttt atcaagtagc cgccccagat
      781 gactacaacg atttacgagg acagctgcaa ttgacctttc aagcggatga aaccgcctat
      841 accgttttat tgggaatggc tcgccttggt gatcaggcga aggtcgagtg gcggattttc
      901 gatatttgat ggcaggatca aggcgtttca gttgcaaacc ttcctctctt tcaattagaa
      961 aaaccgcagc aggaagaagt ttgtgtgctg gtcaccgatg ctggtgaaat tcgtctccgc
     1021 ttatttcctg accaagctcc cctggctgta gccaactggc gctccctagc tgagcaaggc
     1081 gtttatgaca acacaccttt cggctcgtgt cattaaggaa tttgttattc aaggtggcgc
     1141 tttggatggt tctggtgatg aagctgtttc cagctatgag ggctttttcg ctgatgaagt
     1201 gcatcgcgga ctttatcatt ttaatggcgc cttggcctta ggggaccacg gcccccacac
     1261 caacggcaac cagtttttta ttgtgcaaaa cacaaaggcg caggctgacc tgctaatgta
     1321 aagcaagcat acttggagct tggaggacta ccggagctgg atggtcgtta tactgttttt
     1381 ggacaggtat accaagggtt agaaatcgta gcagcgatcg cagctcagcc gacaaacagt
     1441 gaagatgtac cgattgagcc agtgttcatt cgacaaatta acttcgaaaa aacatcgtaa
     1501 aaagacactc actgacttca gcaaaagctc tattcttgag ctggctgcag ctagtgagtg
     1561 tctttcattt atccataaga taaagcttgg attcaataaa taaataaatg ttttggttaa
     1621 agctgtgacc agcaaatgag gaaccgtgcg agccagttga tctgccaatg caaacatttc
     1681 tttaggtgaa ggcgctggcg tgtctgccaa cggatactcc agtcccaatg cttggtaacc
     1741 gtgcatacca tagcagtggt acggtagtaa ttctaacggt acgaaccgat caagatctgc
     1801 cacaaaacaa gcaatcgtca gcagctcggt caggttcata ttgatacctg gaaccacagg
     1861 aactcgaatt cgcacttcgc agttaggata ctcaattaaa aagcgacgaa tattcttcaa
     1921 aatttgttgg ttatctaagc cggtccattg tttgtggagc ttgctggtaa acatttttac
     1981 atccacaaac aatgtatcca catagggagc taccttttgg atttcattat aagcaccaca
     2041 aaagctggtt tccagtacgg tattgattcc aatgtatttc gatttttgca aaatttcttt
     2101 agcaaaatcc gcctgaacca gtgcctcgcc tccgctaatg gtcactccgc catccgagtg
     2161 aaagtaaaaa acagcatcct tctcaatctc atccattacc tcttcagcgg tcatggtctg
     2221 gccaaatcct ttttcaatct gcttgctttg tgattcggga atcgaacacc aggcacagcg
     2281 taatgggcag ccctttaaat aaacaacggt ccgtaaacca gcaccatcat gtagagaacc
     2341 ctgttctatt cttaatactg ttccttccat atagattttt gaattacaca ctagtttaaa
     2401 ctaaaacaca caaggaaaaa cttaccattt aatcataaaa ttagctcata taaatatact
     2461 aggatgtaaa atagactggt caaaatctgg tcaaaaaaga ggactaatac aggtagtcct
     2521 cttttttgtt attttaatat tctaaatcat tttttattgg tttattccct tattcgatgt
     2581 agactcaaat cactatatca ctagatatca aacggcgtca tacggaatca aaaacatcaa
     2641 atttgacctg ttaaatggtc attgaataac attcaaaatc aataaaacgg agtcagacac
     2701 ggagtcaaaa acgctgagag taaaaaatat atacagcctt gtaggtaaag taccacaggg
     2761 ctgtatattt tttatttcag attaccttaa atgattccat ttacttttta tctcattttt
     2821 tcctactagt tagtatcaaa tactctccta ttttctcaat aaactatttt tggatacatg
     2881 gtatctgaaa cagctaaaac cttgtcatta cagcaaaaaa tcacgttat
//
LOCUS       DASHXG010000128         2918 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.140, whole genome shotgun sequence.
ACCESSION   DASHXG010000128 DASHXG010000000
VERSION     DASHXG010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.140"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            205..1173
                     /locus_tag="U2R59_002810"
     CDS             205..1173
                     /locus_tag="U2R59_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEM8967133.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1166..2197
                     /gene="vanA"
                     /locus_tag="U2R59_002811"
     CDS             1166..2197
                     /gene="vanA"
                     /locus_tag="U2R59_002811"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEM8967134.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2203..2811
                     /locus_tag="U2R59_002812"
     CDS             2203..2811
                     /locus_tag="U2R59_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEM8967135.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          863 a          559 c          708 g          788 t
ORIGIN      
        1 taatttttta ggaaaatctc aaggttatct ttactttttc ttaggaaatt aacaatttaa
       61 tattaagaaa cggctcgttc ttacacggta gacttaatac cgtaagaacg agccgttttc
      121 gttcttcaga gaaagatttg acaagattac cattggcatc cccgttttat ttggtgcctt
      181 tcacagaaag ggttggtctt aattatgaat aacatcggca ttactgttta tggatgtgag
      241 caggatgagg cagatgcatt ccatgctctt tcgcctcgct ttggcgttat ggcaacgata
      301 attaacgcca acgtgtcgga atccaacgcc aaatccgcgc ctttcaatca atgtatcagt
      361 gtgggacata aatcagagat ttccgcctct attcttcttg cgctgaagag agccggtgtg
      421 aaatatattt ctacccgaag catcggctgc aatcatatag atacaactgc tgctaagaga
      481 atgggcatca ctgtcgacaa tgtggcgtac tcgccggata gcgttgccga ttatactatg
      541 atgctaattc ttatggcagt acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat
      601 gatttcaggt tggacagcga ccgtggcaag gtactcagcg acatgacagt tggtgtggtg
      661 ggaacgggcc agataggcaa agcggttatt gagcggctgc gaggatttgg atgtaaagtg
      721 ttggcttata gtcgcagccg aagtatagag gtaaactatg taccgtttga tgagttgctg
      781 caaaatagcg atatcgttac gcttcatgtg ccgctcaata cggatacgca ctatattatc
      841 agccacgaac aaatacagag aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt
      901 ccacttgtag atacctatga gttggttaaa gcattagaaa acgggaaact gggcggtgcc
      961 gcattggatg tattggaagg agaggaagag tttttctact ctgattgcac ccaaaaacca
     1021 attgataatc aatttttact taaacttcaa agaatgccta acgtgataat cacaccgcat
     1081 acggcctatt ataccgagca agcgttgcgt gataccgttg aaaaaaccat taaaaactgt
     1141 ttggattttg aaaggagaca ggagcatgaa tagaataaaa gttgcaatac tgtttggggg
     1201 ttgctcagag gagcatgacg tatcggtaaa atctgcaata gagatagccg ctaacattaa
     1261 taaagaaaaa tacgagccgt tatacattgg aattacgaaa tctggtgtat ggaaaatgtg
     1321 cgaaaaacct tgcgcggaat gggaaaacga caattgctat tcagctgtac tctcgccgga
     1381 taaaaaaatg cacggattac ttgttaaaaa gaaccatgaa tatgaaatca accatgttga
     1441 tgtagcattt tcagctttgc atggcaagtc aggtgaagat ggatccatac aaggtctgtt
     1501 tgaattgtcc ggtatccctt ttgtaggctg cgatattcaa agctcagcaa tttgtatgga
     1561 caaatcgttg acatacatcg ttgcgaaaaa tgctgggata gctactcccg ccttttgggt
     1621 tattaataaa gatgataggc cggtggcagc tacgtttacc tatcctgttt ttgttaagcc
     1681 ggcgcgttca ggctcatcct tcggtgtgaa aaaagtcaat agcgcggacg aattggacta
     1741 cgcaattgaa tcggcaagac aatatgacag caaaatctta attgagcagg ctgtttcggg
     1801 ctgtgaggtc ggttgtgcgg tattgggaaa cagtgccgcg ttagctgttg gcgaggtgga
     1861 ccaaatcagg ctgcagtacg gaatctttcg tattcatcag gaagtcgagc cggaaaaagg
     1921 ctctgaaaac gcagttataa ccgttcccgc agacctttca gcagaggagc gaggacggat
     1981 acaggaaacg gcaaaaaaaa tatataaagc gctcggctgt agaggtctag cccgtgtgga
     2041 tatgttttta caagataacg gccgcattgt actgaacgaa gtcaatactc tgcccggttt
     2101 cacgtcatac agtcgttatc cccgtatgat ggccgctgca ggtattgcac ttcccgaact
     2161 gattgaccgc ttgatcgtat tagcgttaaa ggggtgataa gcatggaaat aggatttact
     2221 tttttagatg aaatagtaca cggtgttcgt tgggacgcta aatatgccac ttgggataat
     2281 ttcaccggaa aaccggttga cggttatgaa gtaaatcgca ttgtagggac atacgagttg
     2341 gctgaatcgc ttttgaaggc aaaagaactg gctgctaccc aagggtacgg attgcttcta
     2401 tgggacggtt accgtcctaa tcgtgctgta aactgtttta tgcaatgggc tgcacagccg
     2461 gaaaataacc tgacaaagga aagttattat cccaatattg accgaactga gatgatttca
     2521 aaaggatacg tggcttcaaa atcaagccat agccgcggca gtgccattga tcttacgctt
     2581 tatcgattag acacgggtga gcttgtacca atggggagcc gatttgattt tatggatgaa
     2641 cgctctcatc atgcggcaaa tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg
     2701 cgctccatca tggaaaacag tgggtttgaa gcatatagcc tcgaatggtg gcactatgta
     2761 ttaagagacg aaccataccc caatagctat tttgatttcc ccgttaaata aacttttaac
     2821 cgttgcacgg acaaactata taagctaact ctttcggcag gaaacccgac gtatgtaact
     2881 ggttcttagg gaatttatat atagtagata gtattgaa
//
LOCUS       DASHXG010000129         2888 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.141, whole genome shotgun sequence.
ACCESSION   DASHXG010000129 DASHXG010000000
VERSION     DASHXG010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.141"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            89..406
                     /locus_tag="U2R59_002813"
     CDS             89..406
                     /locus_tag="U2R59_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HEM8967136.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="U2R59_002814"
     CDS             complement(497..862)
                     /locus_tag="U2R59_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967137.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1070..1552
                     /locus_tag="U2R59_002815"
     CDS             1070..1552
                     /locus_tag="U2R59_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967138.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1749..2639
                     /locus_tag="U2R59_002816"
     CDS             1749..2639
                     /locus_tag="U2R59_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEM8967139.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          996 a          446 c          551 g          895 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat
     1021 agaaaattgt atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa
     1081 agcagtaatc gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt
     1141 tacatgggta aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg
     1201 atttgtggtt tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg
     1261 tctcttatta ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg
     1321 cttattagta tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg
     1381 tttgagcgag agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa
     1441 accatggttc tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac
     1501 agaaatcagg ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat
     1561 catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt
     1621 attatgtaaa gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta
     1681 cagcaaccat acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga
     1741 gcaataaaat gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat
     1801 gcggctcagg atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa
     1861 atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag
     1921 cacaagaaag ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa
     1981 gcggaactgg tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat
     2041 ttgcagaaga aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg
     2101 tcgggatggc accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat
     2161 tgattgatat ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa
     2221 aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg
     2281 gactggatgg tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc
     2341 agctggtaag tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt
     2401 ccacacaagc actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca
     2461 gctggggaat ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc
     2521 aaaaattctt agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg
     2581 gctatttacc aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac
     2641 tagcagataa acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc
     2701 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     2761 ctaataccga gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag
     2821 aactgtcgta actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata
     2881 aaacttag
//
LOCUS       DASHXG010000130         2779 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.142, whole genome shotgun sequence.
ACCESSION   DASHXG010000130 DASHXG010000000
VERSION     DASHXG010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.142"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1340
                     /locus_tag="U2R59_002817"
     CDS             <1..1340
                     /locus_tag="U2R59_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEM8967140.1"
                     /translation="ALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVP
                     VEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGI
                     KNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKY
                     NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDG
                     SKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADK
                     NGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGS
                     NSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1474..>2779
                     /locus_tag="U2R59_002818"
     CDS             1474..>2779
                     /locus_tag="U2R59_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEM8967141.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNF"
BASE COUNT         1089 a          380 c          541 g          769 t
ORIGIN      
        1 cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca attgatacca
       61 acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt acgaaagata
      121 cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa tatgaaccaa
      181 cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat aatgttacta
      241 acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc ggtacaattg
      301 ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca gacggtacga
      361 aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca gataaataca
      421 atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca tctgagggaa
      481 ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag aaagtagatg
      541 ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat ggatcatctg
      601 atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat aaatataatc
      661 ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct gagggaatta
      721 agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa gtagatgtta
      781 gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga tctaaagaag
      841 aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct caagttgatc
      901 ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca gaggtgacag
      961 ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt aattttacag
     1021 ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact gatgaatctg
     1081 gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac agtggaaaaa
     1141 acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa gacaaaaata
     1201 gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac agtaatatct
     1261 ttactattag cggtggttta atactgttag gaacgttagg attattaggg tataaaaatc
     1321 gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa gaggaagaat
     1381 ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta aagatgaata
     1441 tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat tattggttca
     1501 aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa ttatgaagtt
     1561 attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc gttatttata
     1621 aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac actaaattct
     1681 gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca aaataaaaag
     1741 attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa agttatatta
     1801 gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc taatattttt
     1861 tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga tagtactatt
     1921 aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga agccataaga
     1981 aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc gacttattac
     2041 gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat acatctttgt
     2101 ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat agtcactaca
     2161 agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct atctaatagt
     2221 ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac taatgaatac
     2281 cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac tttttttacg
     2341 tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac agcttatatt
     2401 gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt tacaaatggc
     2461 ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac agcacgatta
     2521 ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc ttttttgaga
     2581 aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag aatagtaggt
     2641 gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc tcttgctata
     2701 gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca tcctagtttt
     2761 agccaaccct ataatttta
//
LOCUS       DASHXG010000131         2778 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.143, whole genome shotgun sequence.
ACCESSION   DASHXG010000131 DASHXG010000000
VERSION     DASHXG010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.143"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..197
                     /locus_tag="U2R59_002819"
     CDS             <1..197
                     /locus_tag="U2R59_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967142.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="U2R59_002820"
     CDS             314..811
                     /locus_tag="U2R59_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8967143.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="U2R59_002821"
     CDS             898..1290
                     /locus_tag="U2R59_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8967144.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..>2778
                     /locus_tag="U2R59_002822"
     CDS             1274..>2778
                     /locus_tag="U2R59_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8967145.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKA"
BASE COUNT          839 a          518 c          596 g          825 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagc
//
LOCUS       DASHXG010000132         2676 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.144, whole genome shotgun sequence.
ACCESSION   DASHXG010000132 DASHXG010000000
VERSION     DASHXG010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.144"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..750
                     /locus_tag="U2R59_002823"
     CDS             <1..750
                     /locus_tag="U2R59_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967146.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTIIEHLWKYF"
     gene            2301..>2676
                     /locus_tag="U2R59_002824"
     CDS             2301..>2676
                     /locus_tag="U2R59_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967147.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMR"
BASE COUNT          973 a          369 c          535 g          799 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      661 attcaatctg tcgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaacg
      721 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
      781 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      841 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      901 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      961 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
     1021 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
     1081 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
     1141 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
     1201 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
     1261 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
     1321 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
     1381 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
     1441 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
     1501 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
     1561 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
     1621 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
     1681 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1741 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1801 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1861 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1921 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1981 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     2041 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     2101 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     2161 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     2221 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     2281 caaaggagtg taacccataa atgacctaca aacatcttac catagacgaa ctgacaatga
     2341 tagaatcata ttatcttcaa cataataagc cggttgaaat cgctaaccga atgggacgtg
     2401 ctatacaaac tatttataat gtagtcaata agttcaagca aggcaagact gctcttgatt
     2461 attggcacca gtataaagaa aataagaaaa aatgtggtag aaaagtcatt caattacctg
     2521 ctcatgaagt agattacatt aaagagaaag tcactcttgg ttggacgcct gacgtcatta
     2581 tcgggcgaaa agaaaggcct gtttcatgcg gtatgagaac actttatcgt ttattttcta
     2641 aaggaatatt tgatattgac acactaccga tgagag
//
LOCUS       DASHXG010000133         2630 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.145, whole genome shotgun sequence.
ACCESSION   DASHXG010000133 DASHXG010000000
VERSION     DASHXG010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.145"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            16..177
                     /locus_tag="U2R59_002825"
     CDS             16..177
                     /locus_tag="U2R59_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967148.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
     gene            190..693
                     /locus_tag="U2R59_002826"
     CDS             190..693
                     /locus_tag="U2R59_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEM8967149.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            753..1142
                     /locus_tag="U2R59_002827"
     CDS             753..1142
                     /locus_tag="U2R59_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8967150.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            1129..>2630
                     /locus_tag="U2R59_002828"
     CDS             1129..>2630
                     /locus_tag="U2R59_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEM8967151.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKG"
BASE COUNT          783 a          435 c          606 g          806 t
ORIGIN      
        1 caatccttag tcttactggc aattgtggtc attggtttgt ttttaggatt taagcgggag
       61 ttttccaaac tgattggctt tttggtgatt gctttgattg cggtcggatt ggtctttaat
      121 gcttctgggg tgaaggatgt cttactcagt ttgtttaacc gaattgtcgg tgcgtaaggg
      181 ggaagcacga tggaacagat gcgtgtttat attgcgaacc tcgggaaata taacgaaggt
      241 gaattggtgg gggcgtggtt taccccacct gtcgattttg atgaagtgaa agaacgaatt
      301 gggttaaatg acgaatacga ggaatatgca attcatgatt atgaacttcc ctttgagatt
      361 gatgagtata cgccaattga ggaaattaat cggttgtgtg gcttagcgga ggaacttgaa
      421 ggaacgccag ttggtgaagt tgcttctgag attcaacatg ctttcttcaa ttcttttgag
      481 gagatggtag agcatgtgga tgatattatc tattatccag attgcgatga tatgagtgat
      541 gtagcatatt tcttgattgt agaagctggt gattttggag aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtaga gacttggaga ttggaggcaa ttatttggta
      661 acgagtcgag gtgtttttga gtatccatat taacaaaatt attgaagggt agttgatttc
      721 taaactatcc ttctttttaa aggaatgatt tgatgaagaa aataaaaagc tacaccagta
      781 tttgggcagt tgaaaaggtc atttatgcaa ttaatgactt tcaactgcct tttcctgtga
      841 cttttaacca gatggcttgg tttgttttat ccttgctgtt tgtcatcgta tttgcccatg
      901 tgcctccact atctatgata gagggggcct ttttaaaata cttaggtata ccggtggcag
      961 ttacttggtt catgtcgcaa aaaacgtttg acggtaagaa accattggga tttttacgat
     1021 cttttattag ctatcactta cgatttaagg tcactttcgc aggaaagaaa gtcaaagaac
     1081 agaagaaacg atgggacgaa cccattactc tggtaaggag tgtgaactat gtacccgatt
     1141 aagtatattg aaaataatct tgtctttaat caagagggag aatgttttgc ctactatgag
     1201 ttaatacctt acaattactc ctttttgtca cctgaacaga aatatcaagt ccacgataac
     1261 tttcgtcaat tgattgcgca aaatcgtgaa ggcaagattc atgccttaca aattgccaca
     1321 gaaagtagta ttcgtgccac gcaagaacga tcaaaaaagg aaattaccgg gcgattaaca
     1381 gaagtagcga aacaacgaat tgatttacag acagaggcat tagtatccat gattggcgat
     1441 agtcagattg attatcgctt ttttattggc ttcaaactga ttgcgacaga tgaagaggtc
     1501 aatctaaaga atctcaagaa atctttcttc tccggctttc aagaatttgt ctatggagtg
     1561 aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg ccgatatacc
     1621 aagcttgaaa aactaatgga aagtaaattg gctcgaagat ttaaagtcag acgagtcaca
     1681 ccgagtgatc tgatgtattt gattgaacat atctatggcg aaaagggtac accatttgaa
     1741 gaatatgaat ttcagctacc aaagaaaaag ctgaagtcgg aaactttggt gaaacgttac
     1801 gacttattac gtcccagtcg ttgtttgatt gaagaaaagc cccggtactt atgcatggaa
     1861 catgagaatc atgaatcata tgtagcgtac ttaacaatta atacaattgt gggggaaatg
     1921 gagtttccct cctcagaact tttctattac cagcaacaac aatttacatt cccaattgac
     1981 actagtatga atgtggagat tgtgacgaac aaaaaggcac ttgctaccgt tcgcaataag
     2041 aaaaaggaat taaaagactt ggacaaccat gcctatcaat ctgacaatga aacaaattcc
     2101 aatgtcttag atgcattgga ttccgtagat gaattggaaa ctaccttgga tcagtccaaa
     2161 gaatccatgt acaaactgag ctatgtggtt cgagtaagtg ccgaatcagt agatgaacta
     2221 aagcgccggt gtgatgaagt gctagatttt tatgatgata ccaatgtaaa actagtccgg
     2281 ccttttggcg atatgatggg gctacatgaa gaattcttac cttctagtaa gcgatacatg
     2341 aatgattata tccagtatgt tacgtctgat tttctcgccg gacttggttt tggcgccact
     2401 cagatgttag gggagttgga aggcatttac tttggttata acgtagatac ggggcgcaat
     2461 gtttacctga aaccggcatt ggcctcacaa ggggtcaagg attcagttac caatgcgcta
     2521 gcagcggcat tcctcggttc actcggtggc ggaaagtcct ttagtaacaa tctcttagtt
     2581 tattacgccg tcctttttgg tggacaagct gtgattgtcg atccaaaagg
//
LOCUS       DASHXG010000134         2492 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.146, whole genome shotgun sequence.
ACCESSION   DASHXG010000134 DASHXG010000000
VERSION     DASHXG010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.146"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(367..1659)
                     /locus_tag="U2R59_002829"
     CDS             complement(367..1659)
                     /locus_tag="U2R59_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8967152.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1933..2193)
                     /locus_tag="U2R59_002830"
     CDS             complement(1933..2193)
                     /locus_tag="U2R59_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967153.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          382 g          801 t
ORIGIN      
        1 tgtatgggct actctgtgat acttattagc cattaaacta ttttacccac atagcatata
       61 ttttgaaatc gttcattccg taaattcaac taaatatgcc taaaaaaata aaaaatctaa
      121 gatagaataa gatttattca gtcttagatg gatttatagc aactttttcg taacaacttt
      181 aaaaaatacg aaaagaaaga gctgttttac tctgactacg ttgctaaatt gtcgtttaat
      241 cattcattta aaccaaatct ttttttatag aattcgtttt aatcctcctg aatccaaaaa
      301 ctatgaaaac cgtaattaaa tagttaagag tttttaacca ccataattct ctcggctatt
      361 ttgaaatcag ataaattttg atcggacaca tagttgaata aacctaccgt tgttacggaa
      421 ggtaaatcgc atacttttca ttctagagga gaaggtctcg ttgatcatta actgattaag
      481 caccatagcc cagttttgaa ttcgaccacc tgaccacttc gcgtgtaatt ctttcgtgcg
      541 taaataaagt agttttagga gtgcattctc attagagaac gctccttttt ttgtgacttt
      601 tctgaagctg gagtggacac tttcaaccgc attggtagtg tacataattt ttcgaatggc
      661 actaccataa tcaaatagtt gttcaacatg tgcaaagttc cgtttccaga catctacagc
      721 accagaataa tgagaccacc gattttgaaa actgtcaaaa gcagcatgtg cagcgtttag
      781 agaagaagca ccgtagaact ttttcatatc tcggcagact tccttatagt ccttacttgg
      841 aatatagcgc aatgcatttc gaacaagatg aacaatacag cgctgaacaa ttaccgatgg
      901 aaagatcgct tttgcgcctt cttcgaggcc agaaacaccg tccatcgaaa tgaaaaagac
      961 atcttcgaca ccacgtgctt tcagttcatc aaatacttgc atccagcgat ttttagattc
     1021 tgtttgattt aaccataatc ctaaaatctc cttatttcct ttgagatcat agccaagaat
     1081 ggtgtataca gcatattctt tggcttcata attttctcgt aaagtaacat acatacaatc
     1141 aacgaataga aaggcataac actttgctag ggggcgggct tgccattctt ccaattcagg
     1201 aaggacagcg tcagtgatat ctgaaatcat ttcatgggaa atatcaaagc cataaatagc
     1261 ttcgacggtt gcggcaatat ctcgttgact cattcctcgt gcatacatgg aaagaacctt
     1321 cccttcgatg tcggagacat ctcgttttct cttaggaatt aactctggtt caaaggaagc
     1381 ttcccggtct ctaggaacat caatagctac ttcaccaaaa ctggttttaa gcgttttagt
     1441 tccatagcca tttcgacggt tatcgtgttc cttaggctct ttagaatggg catcataacc
     1501 taaatgatta ttcaattctc cttgaagcat tttttcaaaa aggggcccaa acacatcttt
     1561 caaagcatct tgcatgtcat cgacagattc aggttgatag gcattcagaa tggattcagc
     1621 taacttttcg gcatcaggat ttcttttctt tctagccatc gtgtaatcac ctcttgatct
     1681 tattgtagaa aaagaaaaac cgcgaagcaa ccacctgcct aggattaatg gttacttaca
     1741 cggtttatat tacactctca tcattaaaaa agtatctttc gatattacta aacaatgaaa
     1801 ttatctattt gaaatttaaa tctgataata tattgagtgt tccaatgagg gctttgatcc
     1861 tattatccat atctttttca gttttaatat tgatacacat tataagaaaa agaaactttt
     1921 ggttaattta tttcatccca gtgcaaaata taaaaaagta aaatagacca taggcaatag
     1981 attaacaatt aatataatac aagcaaatat tctattcatt gtatttctgc tttcaaaaag
     2041 ttctaatatt gaaagtataa ttccacaaat gcctataata agtatgggaa taagattaga
     2101 aaataacacc ccgagccaat ctgtgaaaat tactatattt actaatatcc ctattaacat
     2161 acctatcata tttattaaat caattttttt cattagatat ttctccttta ttaaatctga
     2221 agtacttata ttaaaataat tctaaactat ttacctcaaa aagtgcaata aattatttct
     2281 gaacaataaa atgatagtca aaacaaaaaa atattgttaa tcgttcagag ccatccgaga
     2341 gtgtaaaata ttttgtgtaa atgaaaaaat ccatacaaaa aaggaaggcg cttctgtaga
     2401 ataaagttaa cgacaaccaa ttcacagaaa agaggacttc cctatgaatg attttactac
     2461 agaaattgtg caaactctag tcactaaagg cg
//
LOCUS       DASHXG010000135         2398 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.147, whole genome shotgun sequence.
ACCESSION   DASHXG010000135 DASHXG010000000
VERSION     DASHXG010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.147"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            207..2069
                     /locus_tag="U2R59_002831"
     CDS             207..2069
                     /locus_tag="U2R59_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8967154.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="U2R59_002832"
     CDS             2069..>2398
                     /locus_tag="U2R59_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8967155.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DASHXG010000136         2016 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.149, whole genome shotgun sequence.
ACCESSION   DASHXG010000136 DASHXG010000000
VERSION     DASHXG010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.149"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(97..195)
                     /locus_tag="U2R59_002833"
                     /pseudo
     CDS             complement(97..195)
                     /locus_tag="U2R59_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(460..915)
                     /gene="tnpA"
                     /locus_tag="U2R59_002834"
     CDS             complement(460..915)
                     /gene="tnpA"
                     /locus_tag="U2R59_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEM8967156.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1158..2016
                     /locus_tag="U2R59_002835"
                     /pseudo
     CDS             1158..2016
                     /locus_tag="U2R59_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          638 a          385 c          368 g          625 t
ORIGIN      
        1 ttatctgtat ttaatacaga ttttatttat tagttcatct gcctattgta ttttattttg
       61 ttgccttacc atctgaagta aatatactct taattgtcaa attaagttag acagatcatc
      121 aatacttacg taactcaaaa atacttccaa aggtgttcga taatccagtg attttctagg
      181 aagattattt ctgcgccagc attttctaat gtttgaattt gtgttttgta atcttggttg
      241 cttgtgctaa ttcttgaata gccgtaaatt gccaaaattt catcaccctt tctggacata
      301 agtttctgac accagttaaa atcaagtcta tcagtaaccc atacacccgt gaggacgggt
      361 gtatttttaa tccccctaga aggggtcgac actcgctgcc ccttaaaagg ggatttttaa
      421 aagaccgcca actgctcatc ttcactcact tacttctctt tattttttaa atggttctac
      481 gtactctctt ttacttataa tatatcgaat gcgatcatca gcttcttgtt cacggatgta
      541 tttttcattt gtcttttgat tcaatccgac tgtactcaca tagtatctct tcgaccaaaa
      601 ggatttgttt ccgtatttat atttgagatt tgcgtgctgc tcgtggatta gtaccgcact
      661 acgacctttc agatacccca taaaactgga tatacatatt tttggtggta ctcgaacaag
      721 catgtgaata tgatctagca ttgcatgtgc ttctatgatt tccacatctt tcatttcgca
      781 caacttccta agtatttttc caagatcttt tcgtaattgc ccatagatta cttttcgttg
      841 atattttggt gtaaaaataa tatgatactt acaattccaa cgagtatatg ctaaactttt
      901 atcgtcattt gacatgaaaa aactcctttc gatctgatga gcggttggta gccactcact
      961 agtatatcga aaggagtttt tatcgctaaa gatacttctt ccacgcgtag aaacgcgcgg
     1021 ttttcttgtt tcgcacgctt tacgcacaaa actgactgaa gtcattaaga aaataaaagg
     1081 gtctaaaact tttaagtttt gtaccgaccc ccaaaagtta gaccaaaaaa tctaactttt
     1141 ggaggtcggt attttttatg gctaagtata cttttgaact taaattaaag atcgttcatg
     1201 attacttgga tggtaaaggc ggaagtgatt atctggcaaa gaaatattcc attaaggctc
     1261 catcacaagt gaagcgctgg atcaatgcct atcaagaatt tggtgaagag ggtctagtaa
     1321 gaaagcgaca aaagaaaaaa tattctgttc aatttaagct ggatgcgata gagttatatc
     1381 taacaagtga gctgtcctat cgtgaagttg ccaacacact taacatgaac aaccctaatt
     1441 tgatcgctag ttggatgcgt caattccgtg agggtgggat cgatggactc tcaaaaacga
     1501 aaggatgtcc acctatcttg tctaagaaaa atgaacccaa aaataagaaa aaatctacaa
     1561 ctaaagcaac gtctaaagaa cgtgaacgca tcgaggagtt ggagaaacga gtccgttccc
     1621 ttcaaattga aaatgccttt ttaaaagaat tgaggaagct gcgaaaacag gaagcccaac
     1681 aacgacgaat gaagcaatcg cacgaatcat cgcaagcctc cgaggaccgt ttaaattagt
     1741 tgagcttcta gaaactttaa agttccctaa ggcaatcttt atgtactggc aaaaacgatt
     1801 ggaccgtaaa aatccagatc aagagattga agcggaaatg cttaaagttc gggagaagca
     1861 caaggattat ggctgtttac ggatgaccaa tgaactaaga aaccgcggtt tctctatcaa
     1921 taaaaagaaa gttcagcgcc tgatcaagaa gctaggaata aaagtaacga catacacacg
     1981 taaatcacgg cgctacaatt cttatcgagg acaagt
//
LOCUS       DASHXG010000137         1979 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.150, whole genome shotgun sequence.
ACCESSION   DASHXG010000137 DASHXG010000000
VERSION     DASHXG010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.150"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(325..528)
                     /locus_tag="U2R59_002836"
     CDS             complement(325..528)
                     /locus_tag="U2R59_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967157.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="U2R59_002837"
     CDS             complement(728..1744)
                     /locus_tag="U2R59_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEM8967158.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          557 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DASHXG010000138         1926 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.151, whole genome shotgun sequence.
ACCESSION   DASHXG010000138 DASHXG010000000
VERSION     DASHXG010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.151"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..159
                     /locus_tag="U2R59_002838"
     CDS             <1..159
                     /locus_tag="U2R59_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8967159.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="U2R59_002839"
     CDS             242..859
                     /locus_tag="U2R59_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967160.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1023..1355
                     /locus_tag="U2R59_002840"
     CDS             1023..1355
                     /locus_tag="U2R59_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967161.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1679..1840
                     /locus_tag="U2R59_002841"
     CDS             1679..1840
                     /locus_tag="U2R59_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEM8967162.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
BASE COUNT          689 a          241 c          389 g          607 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc cttattttta ggaggaatca
     1021 aaatgaacaa tagagaaata ttggcaaaag aaatggcgga tttgaaagca aaagaagcga
     1081 agattagagc gaaacgaaaa cagattagac agaaagaaat gatttcttta gcgaaattat
     1141 attgtaaaaa ggaaggcttt aagacacctg ctgaagcatt agattttttg gaatcaaata
     1201 aaagaaatca ttcagtaaat gatgaggttt tagtatcgct aagaaaattt gcagatggat
     1261 tagtttggca agaaaatggt gcatattggc gtacgaatga tgttaagggt ttgactcaat
     1321 ttatggcaca atttcgttca gaaaatgtga actaaattga ggaggggttg aagtgaaaag
     1381 caatactttt cacttttggt tttttgcgga ataaaaattg tgaaaacaat gacgcaaaaa
     1441 gccaatggtt ttgaacgaaa aaaggacgta aaaaaggaat gcgaaggcag tcgtttttcg
     1501 ttcgcttttt cgtttgagag aaacggagtt tctcatcggc tgttaagccg atatagccct
     1561 cggcagagct tacagacttt acgcagtata agtctagtaa gttatacctt acatggaggt
     1621 ttttccgaat ttagcttgtg attctcgcaa taattttaac gaaaggaagt acacagttat
     1681 ggcctatatg gtggcacgaa cacaaaagca taaagttggg tcgttaaatg gacttcaaaa
     1741 tcatgtagat cgtaaaacga aaaatcatac gaataaagac attgatatta cgaaaagtgg
     1801 ttctgttgca aagttttcca aaaaatctat tttagtgtaa aattgagaaa aaagacagag
     1861 aggatagagt aatgaatcat tttaaaggca aacaattcaa aaaatgacgt cattattgtc
     1921 gctgtt
//
LOCUS       DASHXG010000139         1864 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.152, whole genome shotgun sequence.
ACCESSION   DASHXG010000139 DASHXG010000000
VERSION     DASHXG010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.152"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            17..>1864
                     /locus_tag="U2R59_002842"
     CDS             17..>1864
                     /locus_tag="U2R59_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HEM8967163.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAG"
BASE COUNT          644 a          368 c          371 g          481 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggc
//
LOCUS       DASHXG010000140         1854 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.153, whole genome shotgun sequence.
ACCESSION   DASHXG010000140 DASHXG010000000
VERSION     DASHXG010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.153"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            15..284
                     /locus_tag="U2R59_002843"
     CDS             15..284
                     /locus_tag="U2R59_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967164.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            289..453
                     /locus_tag="U2R59_002844"
     CDS             289..453
                     /locus_tag="U2R59_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967165.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            446..763
                     /locus_tag="U2R59_002845"
     CDS             446..763
                     /locus_tag="U2R59_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967166.1"
                     /translation="MDKKAAMKRIIELTHSESWQEDEEVVAEVQRLGKIANGRIRKKP
                     DKRKQRKRKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYKYL
                     EEE"
     gene            763..1578
                     /locus_tag="U2R59_002846"
     CDS             763..1578
                     /locus_tag="U2R59_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HEM8967167.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            1717..>1854
                     /locus_tag="U2R59_002847"
     CDS             1717..>1854
                     /locus_tag="U2R59_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HEM8967168.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGAGVR
                     SS"
BASE COUNT          704 a          285 c          428 g          437 t
ORIGIN      
        1 taagaggtgg aaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
       61 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
      121 tcgaaggaat taataatgat cgttcgagtt ggagtaaact cagatactat ttcgcactct
      181 atatcgatac aacacaatta agaaatttag cttatacaaa attactattt gttgattgcg
      241 ttaaaggatt gcaaaaacat cttagtgaac ttgagcaggt gtaatcagat ggatctaaaa
      301 acatttacag cacagatcga actaatgcat caagaagctt taagacaaag cgcctcgtac
      361 gaagacaagt ggctcaacac gttccatggt ggacgtgaga gcgcacttga tcaagtactc
      421 aaattattga aaggggaacg tcgggatgga taagaaagcg gcaatgaaac gaatcattga
      481 actgacgcat tctgaaagtt ggcaggaaga tgaagaagtg gttgctgaag ttcagcgact
      541 aggaaagatc gctaatggac gtatacgaaa aaagccagac aaaagaaaac agcgcaaaag
      601 gaaaatcgtc gttgttttac acgaaggcaa aattttgatg caaggaacag ctagtgagct
      661 gtctgcagaa actggatata cgcgtgggac tattcgaacg tacgcttggc gaaatcacac
      721 cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa taatgaacga aaacaaatta
      781 atcaaattgg gtgtagcagg agcagtaatc gtaggtattg gagttatcgg aggatttaag
      841 ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa cggcggtatc
      901 aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt gatccaatat
      961 ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag cgacggcaaa
     1021 aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc agcaaaaatg
     1081 tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt aaaatctaag
     1141 cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt cctttcagga
     1201 gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt tgaatctaaa
     1261 gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga aacacaaaaa
     1321 tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct agatgcagaa
     1381 actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc agaagcagag
     1441 gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg ttatgaagaa
     1501 gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac tgtagttacg
     1561 gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt tcttaggttt
     1621 agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca aagaagatga
     1681 caacaacgat gaaatgaaat tttaggagga gaaataatgg atctcattac acaatacagt
     1741 gatatcatcc tcaagaaaat catggcaaag attcagaaag ataaaaaagc aaaagaacga
     1801 gctgaattag ttaagttaga aatggctgaa acaggagcag gagtgcgaag tagc
//
LOCUS       DASHXG010000141         1847 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.154, whole genome shotgun sequence.
ACCESSION   DASHXG010000141 DASHXG010000000
VERSION     DASHXG010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.154"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            700..>1847
                     /gene="ltrA"
                     /locus_tag="U2R59_002848"
     CDS             700..>1847
                     /gene="ltrA"
                     /locus_tag="U2R59_002848"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8967169.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
BASE COUNT          730 a          281 c          384 g          452 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaaga
//
LOCUS       DASHXG010000142         1674 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.155, whole genome shotgun sequence.
ACCESSION   DASHXG010000142 DASHXG010000000
VERSION     DASHXG010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.155"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(333..>1674)
                     /locus_tag="U2R59_002849"
     rRNA            complement(333..>1674)
                     /locus_tag="U2R59_002849"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          394 a          478 c          365 g          437 t
ORIGIN      
        1 cggttgggtt ttgatccttc ttctagcgat agaagttaga tcaagaaaat aagcaattga
       61 acttattaaa aaactctatc cagctcacaa atcagcctgt acggcaaaaa gatcgatcgt
      121 ctcataaaat caaagatttt atggccgtcc gcctattttg cttcaggcta aacaatttgt
      181 tcagctttca aattcaacgc ggtgttctcg gtttgtatta cttacattta cttcaaatat
      241 ccagttttca atgaacaaaa gtgtttgaga gtaaacctct caaaactgaa caaagtaaaa
      301 acaaattgtg tagcctccgt aatattcctt agaaaggagg tgatccagcc gcaccttccg
      361 atacggctac cttgttacga cttcacccca atcatctatc ccaccttagg cggctggctc
      421 caaaaggtta cctcaccgac ttcgggtgtt acaaactctc gtggtgtgac gggcggtgtg
      481 tacaaggccc gggaacgtat tcaccgcggc gtgctgatcc gcgattacta gcgattccgg
      541 cttcatgcag gcgagttgca gcctgcaatc cgaactgaga gaagctttaa gagattagct
      601 tagcctcgcg acttcgcaac tcgttgtact tcccattgta gcacgtgtgt agcccaggtc
      661 ataaggggca tgatgatttg acgtcatccc caccttcctc cggtttgtca ccggcagtct
      721 tgctagagtg cccaactgaa tgatggcaac taacaataag ggttgcgctc gttgcgggac
      781 ttaacccaac atctcacgac acgagctgac gacaaccatg caccacctgt cactttgccc
      841 ccgaagggga agctctatct ctagagtggt caaaggatgt caagacctgg taaggttctt
      901 cgcgttgctt cgaattaaac cacatgctcc accgcttgtg cgggcccccg tcaattcctt
      961 tgagtttcaa ccttgcggtc gtactcccca ggcggagtgc ttaatgcgtt agctgcagca
     1021 ctgaagggcg gaaaccctcc aacacttagc actcatcgtt tacggcgtgg actaccaggg
     1081 tatctaatcc tgtttgctcc ccacgctttc gagcctcagc gtcagttaca gaccagagag
     1141 ccgccttcgc cactggtgtt cctccatata tctacgcatt tcaccgctac acatggaatt
     1201 ccactctcct cttctgcact caagtctccc agtttccaat gaccctcccc ggttgagccg
     1261 ggggctttca catcagactt aagaaaccgc ctgcgctcgc tttacgccca ataaatccgg
     1321 acaacgcttg ccacctacgt attaccgcgg ctgctggcac gtagttagcc gtggctttct
     1381 ggttagatac cgtcaaggga tgaacagtta ctctcatcct tgttcttctc taacaacaga
     1441 gttttacgat ccgaaaacct tcttcactca cgcggcgttg ctcggtcaga ctttcgtcca
     1501 ttgccgaaga ttccctactg ctgcctcccg taggagtttg ggccgtgtct cagtcccaat
     1561 gtggccgatc accctctcag gtcggctatg catcgtggcc ttggtgagcc gttacctcac
     1621 caactagcta atgcaccgcg ggtccatcca tcagcgacac ccgaaagcgc cttt
//
LOCUS       DASHXG010000143         1576 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.156, whole genome shotgun sequence.
ACCESSION   DASHXG010000143 DASHXG010000000
VERSION     DASHXG010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.156"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            123..1292
                     /locus_tag="U2R59_002850"
     CDS             123..1292
                     /locus_tag="U2R59_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HEM8967170.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          560 a          255 c          258 g          503 t
ORIGIN      
        1 ttttacactc tctattatga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
      841 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
      901 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
      961 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1021 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1081 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1141 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1201 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1261 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1321 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1381 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1441 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1501 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1561 ccatggataa taataa
//
LOCUS       DASHXG010000144         1540 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.157, whole genome shotgun sequence.
ACCESSION   DASHXG010000144 DASHXG010000000
VERSION     DASHXG010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.157"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..152)
                     /locus_tag="U2R59_002851"
     CDS             complement(<1..152)
                     /locus_tag="U2R59_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8967171.1"
                     /translation="MSRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQST"
     gene            427..969
                     /locus_tag="U2R59_002852"
     CDS             427..969
                     /locus_tag="U2R59_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967172.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1125..1499
                     /locus_tag="U2R59_002853"
     CDS             1125..1499
                     /locus_tag="U2R59_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEM8967173.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          587 a          190 c          301 g          462 t
ORIGIN      
        1 gttgattgtg cttgcttcat ccatttatcg aaagaagaag gcgtaagctc atactctcga
       61 ataatttctg cgcgaggctt accagcgaga tagagatcga cgatttgttg tttgaattct
      121 tttgaatagg ttcttcgttg acgtcttgac atgaaaaatc ctccagtgtg ttttttatta
      181 ttctacacac cttatttttt ctgtctagtc tagtgtagcc gattcaaatt gatgaagcag
      241 atcccaaagg gctgcttcat caattttttc gtaagtgtcc gtacacttac tgtgcttgct
      301 catatattaa tcgatcatat actaatcgtg taagaacaac tttaagcata atacttatat
      361 tgttatacca tagtttggaa aaataaaaaa ttatatttca tcaacgtttc ataaaaggtg
      421 tgtagaatgt tattgaaagt agctataaaa tgctattgtg taaaaaataa aggaggaata
      481 atttatgaaa aaatagtacc aagaggagca tgcctattac ttgcattatg tttgagctta
      541 agcgcagttg ggtgtcaaaa aagtaatgaa aacaataaaa taaaagaagg acaatccata
      601 agttctgaag aggaaggcat gtcaattaat gcaaatggca aaaatgaaac ttttaagcca
      661 tcagattata cattggaggc aaagaaagaa tatgtttatg aatatttagg gcttaaattt
      721 aaactctcag acaaatttag aaattatata gctgataaaa agatagcgat gttagatgat
      781 caaagtccta tagataaaga actaaagtat gctattttga catttgagaa aatgacagaa
      841 gaacaaaaga atgcagttat agaaaagatg ggcgatggat ataaaaattg gcaaaatgag
      901 cttgaaagaa ttgggactat tggtatattt gaaaaaaata catcagaaga aaaaaatcta
      961 aaattataaa atgtgatact catactaaaa taggagtttc aagtgatgga aaatacgatt
     1021 gctatttaag cacaaatagc ggagctgaaa gtaatcttct ggatgaatta aaaagaactg
     1081 agattcaaat tatagataaa aaagaacgtc ctaaaaatgg ttttgtgcta tcagaaaaaa
     1141 ctgatttaga aaatacagaa gcatttaaca aagaatcggt taaagattta cgtaaactac
     1201 caacaaagga cataaatggc aaggatttta caagtaaaga ttttgagaag tatgatctta
     1261 ctatggtaaa tgtatttgca acttggtgta cagcttgtgt aaaggaaatt cctgatttgg
     1321 ttgaggttca gaatgaaatg aaaagcaagg gtgtaaatat cgttggagtt gttacagatc
     1381 ctgttgatga taacggtgaa aacaaggaag caattgaaaa gtcaaagtta atacatgaaa
     1441 agacaaaggc ttcatatcct ttcttaatgc cagatgtgga atggcaacac tttttttgac
     1501 aaaaattata aggtgttgtg aatgctgcgg tgttatggct
//
LOCUS       DASHXG010000145         1444 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.159, whole genome shotgun sequence.
ACCESSION   DASHXG010000145 DASHXG010000000
VERSION     DASHXG010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.159"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..297)
                     /locus_tag="U2R59_002854"
     CDS             complement(<1..297)
                     /locus_tag="U2R59_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8967174.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
     gene            483..1418
                     /locus_tag="U2R59_002855"
     CDS             483..1418
                     /locus_tag="U2R59_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEM8967175.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          464 a          240 c          302 g          438 t
ORIGIN      
        1 cctttctttt cgcccgataa tgacgtcagg cgtccaacca agagtgactt tctctttaat
       61 gtaatctact tcatgagcag gtaattgaat gacttttcta ccacattttt tcttattttc
      121 tttatactgg tgccaataat caagagcagt cttgccttgc ttgaacttat tgactacatt
      181 ataaatagtt tgtatagcac gtcccattcg gttagcgatt tcaaccggct tattatgttg
      241 aagataatat gattctatca ttgtcagttc gtctatggta agatgtttgt aggtcattta
      301 tggttacact cctttgtttt ctttcgtcgg aaatacaatt tgagtgtacc ataaatgcct
      361 ttttattttt ctaacttaat tttacaattc gcgggttata aaaatgaaca ttgcatagta
      421 gagattcttt gattatacta attcaaggtt atatgaaaaa agagaaatga gatggatgat
      481 ttatgaaact ttggatgaaa atccttttag gcgtcgcttt agctctgatt gttgcgttag
      541 tgtttgcagg gaattatttt tataattatg ctgttgtgcc ttctgagaaa gactttttag
      601 acgaagatac acctggtaca acacagacat ccaaagaaac ggatgcacat aaatggttta
      661 gttcaaaaga aaaccgaagc gattggacca tcacttcaaa agacggtctg aaattatcag
      721 cgatttatct tcctgctgaa acgaaaagtg aaaaaacagc tcttgtggct catggctata
      781 tgggaaacgc tgaaacgatg accaattacg caaagatgtt tcatgatatg ggttacaatg
      841 tccttgttcc tgatgcaaga ggacatggaa aaagcgaagg ggattacatt ggatttggat
      901 ggccagagcg taaagactat gtacagtgga taaacaaagt gctagaaaac aatggaaaat
      961 cgcaagaaat cgttctatac ggtgtcagca tgggagcagc aacagttatg atgactagcg
     1021 gagaaaaact accagataat gtgaaagcaa tcattgaaga ttgcggttat tcttccgttc
     1081 atgatgagct tgcttatcag ctagacgata tgtttagtct tccagcattt ccgcttatgc
     1141 aagtaacgag tctagtgaca aaagtccgtg ctggctactt tttcggtgaa gcaaatgcag
     1201 tggaacaatt gaagaaaaac cagcgcccaa tgctctttat acatggagac gaagatacat
     1261 ttgtaccatt tgaaatgtta gataaggtct atcgtgcaac gaagggacca aaagaaaagt
     1321 atgttgtaaa aggagccgag catgcggaag catacaagac agatcctgaa aaatatcagc
     1381 aagtagtcca acaattttta agccaatatg ttcattgaac gagtttaaaa gtaggggatg
     1441 aaaa
//
LOCUS       DASHXG010000146         1424 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.160, whole genome shotgun sequence.
ACCESSION   DASHXG010000146 DASHXG010000000
VERSION     DASHXG010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.160"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(150..1337)
                     /locus_tag="U2R59_002856"
     CDS             complement(150..1337)
                     /locus_tag="U2R59_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HEM8967176.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DASHXG010000147         1412 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.161, whole genome shotgun sequence.
ACCESSION   DASHXG010000147 DASHXG010000000
VERSION     DASHXG010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.161"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            98..1390
                     /locus_tag="U2R59_002857"
     CDS             98..1390
                     /locus_tag="U2R59_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8967177.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          461 a          288 c          256 g          407 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tc
//
LOCUS       DASHXG010000148         1406 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.162, whole genome shotgun sequence.
ACCESSION   DASHXG010000148 DASHXG010000000
VERSION     DASHXG010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.162"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..693
                     /locus_tag="U2R59_002858"
     CDS             <1..693
                     /locus_tag="U2R59_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967178.1"
                     /translation="PDVLIGRAEFPIACSVRTLYRMFKDKTFDPHDLPMKGKRKPNGH
                     KEKRGKQAFRRSIQDRTTDYIQFNHEFGHLEGDTIVGGKHKSAVITLVERLSKVIITL
                     KPAGRQAIDIENRLNQWFQSVPKHLFKSITFDCGKEFSNWKKISNTNDISIYFADPGT
                     PSQRGLNEHSNGLLRKDGLYKAMDFNKVSETFIQSVASKRNHIPRKSLHYRTPLEVFL
                     SYVGKDDLSSLI"
     gene            complement(680..1285)
                     /locus_tag="U2R59_002859"
     CDS             complement(680..1285)
                     /locus_tag="U2R59_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967179.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
BASE COUNT          473 a          242 c          208 g          483 t
ORIGIN      
        1 ccagatgtcc ttattggtcg agcagagttt cctattgctt gttcggtacg tacactatat
       61 cggatgttta aagataaaac ctttgaccct cacgatttac caatgaaagg gaaaagaaaa
      121 ccaaacggac ataaagaaaa aagaggaaaa caagcttttc gccgttcgat tcaggataga
      181 acaactgatt atatacagtt caatcatgag tttggtcacc tagaaggtga caccattgtc
      241 ggtggaaaac ataaaagtgc ggtgatcacg ttagttgagc gattatctaa agtgatcatc
      301 accttgaaac ccgctggtag gcaagctata gatattgaga atagactgaa tcaatggttt
      361 caatctgtac cgaaacactt gtttaaatcc atcacatttg attgtggaaa agagttctcg
      421 aattggaaaa agattagtaa taccaatgat atttcgattt atttcgctga tccaggaaca
      481 ccttctcaac gaggactaaa tgaacattcg aatggcttat tacgtaaaga tggcttatat
      541 aaagctatgg attttaataa ggtatccgaa acctttatcc aatcggtggc atcaaaacga
      601 aatcatattc ctagaaaatc attacactat cgcacaccat tggaagtatt tttgagttac
      661 gtaggtaaag atgatttgtc tagcttaatt tgacaaacga aactttgtaa aaatattcga
      721 ttgaatattc tatttggcac gactcacttg gcagtatatg tatgtcaata tttttcatct
      781 gtttcatagg tatttcaaaa tctaaactat taaaaacata taattccctg taattattta
      841 catctaactc tactaaattt atctttggaa caatagatcc tccacccatt ccaccataat
      901 aaaaaaaatc ttgttctcta tcaaaatagc acatattaag ctcagtttgt ttatcatcct
      961 caataatttt ataaatcaaa cctatataat catgaatgct ggcaaaaatt ttttttaagt
     1021 caagttctaa atcttcttcg aaaacacatt taatttctcc tactgataat tgatactcta
     1081 tattacatga cttaattagt tttttagatc ccccctccag ataggcatat gtttcaataa
     1141 ttatgttctt tttattgctt ggcaaatttc cgttatttat tgcataaatt aaaaatgact
     1201 gtctatttag cccataatct aatacaactt cttcatactc atatttcttt aaatatttaa
     1261 tatgaaaata tgctgaatta atcaaaactc gagtgttact gttgttattt attgttgttc
     1321 tattgtgtat aaaattgtat aggttgtcat attttcttgg tttagtgaac tactcaccac
     1381 ttagctaaac ctaacggttt cttacg
//
LOCUS       DASHXG010000149         1404 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.163, whole genome shotgun sequence.
ACCESSION   DASHXG010000149 DASHXG010000000
VERSION     DASHXG010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.163"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            724..>1404
                     /locus_tag="U2R59_002860"
     CDS             724..>1404
                     /locus_tag="U2R59_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8967180.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGL"
BASE COUNT          474 a          243 c          336 g          351 t
ORIGIN      
        1 aaaagagtag gcacagcact tcattaaatc aatatttaat gtgtgttgga gaactaaaca
       61 cacgaatagt cgaatgacgg ggtaacgccc tgaaaggcta ctttaatact ctgactggca
      121 gaaacttgag taaacaaggc tctgtcagaa gctcggtgaa gtcggcagac agacaccgta
      181 acagataatg ctgacgaaag attcccagag gtgggcgttg tgtcctatat gccggaagtc
      241 tataaaatat ctatggttag aatgtagatg agaggtctac tgacgaatcc ttgaatgtac
      301 aggtctatat cggggctgga tagaaatgtc cagtgacaca aacagtgtcg ctactgtggg
      361 tgagtaagac tccgcattta tgaaaatcca tataacgtta aaggcgttat caaggtagca
      421 ggcttataga ggaaacctaa ggatatatgt acagatagtg tgtttggaac gttgaaagct
      481 gacaacatgg agattttact gtctgtgaag tgttcacatc agaaagttat tgtgagatta
      541 gcaatgatat aaggtgtgtt aatgtcagtg agagtggtgg cacagtacct atgaaaccgt
      601 gataacaagc ggtggaggga tagccactag tcatatgaag aatagaatta ctaagaaaaa
      661 tggtatgggt tcgagtaaga ctaagagatg tacttgctcc tgcaaacaag gagggtacag
      721 accatgctaa agaaaaacaa gctccgctat aacgagtatt atgatatgca acatatttat
      781 gacgagttat acgcacagag caagaacggt aataactttt ataagttact tgaaattatt
      841 ggttcggaac aaaatatttg tttagcttac cgtaatctga aatcaaacag tggcagtaaa
      901 acggctggaa cggatggaat gacgatagac gatataaaac aactcagcaa tgctgagatt
      961 gttgctaccg ttcgggaaag ccttagcaac taccgcccca aatcagtcag acgtgttttc
     1021 attccaaaag ctgggagcga taaaatgcgt ccattgggga ttccgtgtat ctgggacagg
     1081 ctggtacaac aatgtatcct gcaagtccta gagccgatat gcgaaccaaa gttccataat
     1141 cattcctatg gattccgtgc gaatcgaagt gcccaccatg cagtcagcag agtaacgaca
     1201 ctgataaatt tatcaaaata tcattactgt gttgacgtag acattaaagg atttttcgat
     1261 aatgtcaatc atggaaaact attaaaacaa atctggacac ttggtattcg ggataaaaga
     1321 ttgatttgca ttatcagcaa aatgctgaaa gccgaaattg acggcgaggg tgtcccagaa
     1381 aaaggaacgc cacaaggcgg tctg
//
LOCUS       DASHXG010000150         1381 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.164, whole genome shotgun sequence.
ACCESSION   DASHXG010000150 DASHXG010000000
VERSION     DASHXG010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.164"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            48..1343
                     /locus_tag="U2R59_002861"
     CDS             48..1343
                     /locus_tag="U2R59_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8967181.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          430 a          274 c          263 g          414 t
ORIGIN      
        1 aaatccttta gaattaattt ggctaccaat tcataggagg attcaagatg tctcatactc
       61 agcttatcaa agatacccta aatattctag acctaaatat ctatttcgag gaaaattgtt
      121 taactaaaga aaaatacaaa gggcaaattt gcttgattta caaaggaact cttctgtaca
      181 agccagaaga gtgttcccat tgtctttgtg tcgtcccctc taggatcatt cgttggggga
      241 cgacaaccgt tcggttgtta ctgaatgatg tgtctgagta tcgcacttat ctggagctga
      301 agaaacaacg atttaaatgt aagtcttgcc aaagaacatt cgtagcggat acctctgttg
      361 ctgaaaaaca ctgtttcatt agtcaaaaag ttcgttggtc tgtcattgct cgcttaaaag
      421 agaatacttc catgacggaa atcgctcgtc agaaaaatat ttccacttct tcggtctatc
      481 gtgtcatgaa gcgattctac cgcccattga atcctttcaa acagactttg ccaaaggtct
      541 tatgctttga tgaattcaaa tcggttcgaa gtgttgccag tgcaatgagt tttatcatga
      601 tggacggaca aagccatgca ttattggata ttgtcgaaaa tcgacgcttg ccttatttag
      661 aacgctattt ttctcggttt tcattagcga ctcgtgaagc cgttcaattg attgttattg
      721 atatgtatgc gccttatgtt tcgttggtga aaaagctttt cccgaatgct cagttgatca
      781 tcgatcgttt ccacatcgtc caacatattg gcagaacttt cttgaatcat cgagtgaaag
      841 aaaccacggt acgacttaaa ggaaattccc actctcaacg agggttaggg aaaaaattga
      901 agcgctattg gaaactccta caaaaagaag aagcaaagtt aaactatgaa aaacgggttt
      961 ggcgtgccag ttttaaagat tatttgactg aaagtgagat tgccgatcga ctgttagctg
     1021 cttgtcccaa cttacgccaa ggctatcagt tataccaaga cattctttat gcggtaaaga
     1081 aaagagatca gtcactattt gaggattgtt taactagaga cattagcggt ctgccagaaa
     1141 cctatacaac cactttacga acgtttaaaa agtttctgcc acagatccaa aatgcgcttc
     1201 actacagcta ttcaaacgga ccattggaat gcttaaacaa ccacatcaaa gtattaaaac
     1261 gcaatgcgta cggctttcgc aacttttaca atttcaaact acgaattatg attcgtcatg
     1321 gcaaaacatt tttaaccaaa taaacagaac agaaagaggt tttcttcttt ctgttctgtc
     1381 c
//
LOCUS       DASHXG010000151         1381 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.165, whole genome shotgun sequence.
ACCESSION   DASHXG010000151 DASHXG010000000
VERSION     DASHXG010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.165"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>1381)
                     /locus_tag="U2R59_002862"
     rRNA            complement(<1..>1381)
                     /locus_tag="U2R59_002862"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          286 a          415 c          271 g          409 t
ORIGIN      
        1 actcctcttc agacttactg cttggacaga catttccgat cgtctgcatt ccttagcctc
       61 ctgcgtccct ccattgctca aacaaaaaca acgggtacag gaatatcaac ctgttatcca
      121 tcgcctacgc ctgtcggcct cggcttaggt cccgactaac cctgggcgga cgagccttcc
      181 ccaggaaacc ttagtcattc ggtggacagg attctcacct gtctttcgct actcataccg
      241 gcattctcac ttctaagcgc tccagcagtc ctcacgatct gccttcaacg cccttagaac
      301 gctctcctac caatacacct aaaggtgtac tccacagctt cggtaatatg tttagccccg
      361 gtacattttc ggcgcagggt cactcgacta gtgagctatt acgcactctt taaatggtgg
      421 ctgcttctaa gccaacatcc tagttgtctg tgcaacccca catccttttc cacttaacat
      481 atattttggg accttagctg gtggtctggg ctgtttccct ttcgactatg gatcttatca
      541 ctcacagtct gactcccgga tatgaatgaa tggcattcgg agtttatctg aattcggtaa
      601 cccgagatgg gcccctagtc caaacagtgc tctacctcca tcattctcaa ttccgaggct
      661 agccctaaag ctatttcgga gagaaccagc tatctccaag ttcgtttgga atttctccgc
      721 tacccacacc tcatccccgc acttttcaac gtacgtgggt tcggtcctcc agtgcgtttt
      781 accgcacctt caacctggac atgggtagat cacatggttt cgggtctacg actacatact
      841 caaacgccct attcagactc gctttcgctg cggctccgtc tcttcaactt aacctcgcat
      901 gcaatcgtaa ctcgccggtt cattctacaa aaggcacgcc atcacccatt aacgggcttt
      961 gacttgttgt aggcacacgg tttcaggttc tatttcactc cccttccggg gtgcttttca
     1021 cctttccctc acggtactgg ttcactatcg gtcactaggg agtatttagc cttgggagat
     1081 ggtcctcccg gattccgacg gaatttctcg tgttccgccg tactcaggat cctcctaggt
     1141 gtcttccaca tttcgtctac ggggttttta ccctctttga ctgacttttc caagtcattc
     1201 gactatctga aagaactacc atattggagt cctacaaccc caacaagcaa gcttgctggt
     1261 ttgggctttt cccgtttcgc tcgccgctac tcagggaatc gaattttctt tctcttcctg
     1321 caggtactta gatgtttcag ttctctgcgt ctacctcgaa tgtgctatgt attcacacaa
     1381 t
//
LOCUS       DASHXG010000152         1366 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.167, whole genome shotgun sequence.
ACCESSION   DASHXG010000152 DASHXG010000000
VERSION     DASHXG010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.167"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            31..1332
                     /locus_tag="U2R59_002863"
     CDS             31..1332
                     /locus_tag="U2R59_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8967182.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          444 a          275 c          252 g          395 t
ORIGIN      
        1 caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcatat caaactacta
       61 cttggaatca aagataaaaa cattttcatc acaaatgtgg aatcgaagag cattaagaat
      121 atcaagagtc ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg tcctttgtgt
      181 aaacagatga atcatgaagg catgatcgtt aagaacggaa agaaaaaatc gctcattcaa
      241 cttaataaat gtgcgaacca actgacttat cttgctttag cgaaacaacg ctaccactgt
      301 cgtggctgcc acacctattt tacggcgaat acctacattg tcgatagaaa ctgctttatc
      361 gctaaacaag tgcgctataa aattttagaa gagctaactg aaaaacaagc aatgacgaca
      421 attgctaagc attgcggcgt ttcttggtcg accgtttctc ggacactcgc ttctctgatc
      481 cccatgacaa aagtaaaaag aaattggtta ccgcgttgtt tattaatgga tgaatttcgt
      541 tcactgaaaa atcaagtcgg tccctactcc ttttcttgta tggatggcga tactggaaaa
      601 ttactggata ttcttccttc acggaagaaa aaggctctcg tttcttattt tatgcaattt
      661 gaacgacgcg cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt ttcttatgcc
      721 tctctgataa aggaatgttt tccaaaggca aaactcgttg tggatcgttt tcacattgtc
      781 aaacatctca ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag ctttgatcga
      841 aacgatccaa cacaagccaa atattatcga caattaaagg cgttgtctcg gcttctgatc
      901 aaacgacagg acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt tggttgggcg
      961 tatctcaccg aaagtgaagt ggtggatcgt ctgctttcga tctctgacga attacgaatc
     1021 gcctattttt actatcaaga aattcttcaa gcgtttcacg acaaagaggc ggacactttc
     1081 tttaaacttg taagaacgat gcccaattcc gttccaaaag aactgcattc tataaaaaaa
     1141 gcttttataa actatgaatc cggcattcgt ttagccctcg aattgcctta ttcaaatgcc
     1201 aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gagtcgctta tggctttcga
     1261 agctttcgga aaatgaagac cagaattttc ttactaaata atctgattac ctatgaatca
     1321 aaaaacatct aaagtagaaa aggaattcta ccttagatgt tcttat
//
LOCUS       DASHXG010000153         1364 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.168, whole genome shotgun sequence.
ACCESSION   DASHXG010000153 DASHXG010000000
VERSION     DASHXG010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.168"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            82..>1364
                     /locus_tag="U2R59_002864"
     CDS             82..>1364
                     /locus_tag="U2R59_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HEM8967183.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DASHXG010000154         1355 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.169, whole genome shotgun sequence.
ACCESSION   DASHXG010000154 DASHXG010000000
VERSION     DASHXG010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.169"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1355
                     /locus_tag="U2R59_002865"
     rRNA            <1..1355
                     /locus_tag="U2R59_002865"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DASHXG010000155         1321 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.170, whole genome shotgun sequence.
ACCESSION   DASHXG010000155 DASHXG010000000
VERSION     DASHXG010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.170"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(372..445)
                     /locus_tag="U2R59_002866"
     tRNA            complement(372..445)
                     /locus_tag="U2R59_002866"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(409..411),aa:Ile,seq:cat)
     gene            complement(1000..1314)
                     /locus_tag="U2R59_002867"
     CDS             complement(1000..1314)
                     /locus_tag="U2R59_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967184.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          488 a          209 c          195 g          429 t
ORIGIN      
        1 actaattaac taccactcca attataagtc tttttcccat tattttttac agttatatgg
       61 tatgcttttt aatggcttca aatataaaag agtttaaagc gtaacacact tatggggaag
      121 tggtttttgg ggaacgcttt aaactcttct ttattattat ctcacaatat aacccaaatg
      181 tctttccatt taaaaatcaa agtaaaactt ttcaaatata cagaagtata actatgtgaa
      241 acatcctttc attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg
      301 aagaaaagct ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaatt
      361 ggctacatta atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg
      421 ctctgaccaa ctgagctaag ggtagtggtt gttgccacat aaagccataa acaatcaacc
      481 agtagaatgc gtggcaacaa acctgttatc gcatatcttg gagtgtgact atttatgagt
      541 gatagtgaag atatgcgtct ccatatatgt atggttgaga cagataaaca tgtatgaaaa
      601 acgttgttaa atcaacgttt ttttattttg gtcaaggaga gaaaagtaga gaaatacaaa
      661 attttttgca ttgattttgc attcaaaaaa acattcaaac atttagaaat ccccaatacg
      721 tattcaggaa aatctatttt aaggtttaca aaaagaactt ttgttcgtac actctttttg
      781 aggtgaactt ttatgctgat ggaaggaaaa acacaattat ggtttaagca tgttccttca
      841 aataagtttt ttaattataa actctagaga aattaattca tcctaacata aaataattgt
      901 tcactcaaaa gtttttctag aacaattaaa acagcaggct tcacattcgc tatacatttg
      961 taagaagtaa taattcctgt actaaaaggc ataattgctt taattatttt ttgacttctc
     1021 ttcaaacaca agaagtagtt gtgtaataat tgcagaaata aggattccaa taatagatat
     1081 aaaatttgac atggaaacgt ctataacatt aaaagaataa agtgttgaag aaagtaaact
     1141 gattgaaata acccctccgt aaaaaatagt ctgtgaatat acccactttt tttcagaaga
     1201 cgtacttcgt ttggttctaa aacctatccc tgcatttcta ctcttatcaa aaaaccaaat
     1261 atttagaagt aataatattg ctattattaa gataaaatta ctgtaaaaat ccaaaagcta
     1321 t
//
LOCUS       DASHXG010000156         1291 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.171, whole genome shotgun sequence.
ACCESSION   DASHXG010000156 DASHXG010000000
VERSION     DASHXG010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.171"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            225..1100
                     /locus_tag="U2R59_002868"
                     /note="aph(2'')-Ia"
     CDS             225..1100
                     /locus_tag="U2R59_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HEM8967185.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          550 a          105 c          207 g          429 t
ORIGIN      
        1 caagatatat taaattgatt tttgaatttt tgaaaaaaga aagaaatgct aatgcagtta
       61 ttttagaccc tcataaaaat aatccaagag caataagggc ataccaaaaa tctggtttta
      121 gaattattga agatttgcca gaacatgaat tacacgaggg caaaaaagaa gattgttatt
      181 taatggaata tagatatgat gataatgcca caaatgttaa ggcaatgaaa tatttaattg
      241 agcattactt tgataatttc aaagtagata gtattgaaat aatcggtagt ggttatgata
      301 gtgtggcata tttagttaat aatgaataca tttttaaaac aaaatttagt actaataaga
      361 aaaaaggtta tgcaaaagaa aaagcaatat ataatttttt aaatacaaat ttagaaacta
      421 atgtaaaaat tcctaatatt gaatattcgt atattagtga tgaattatct atactaggtt
      481 ataaagaaat taaaggaact tttttaacac cagaaattta ttctactatg tcagaagaag
      541 aacaaaattt gttaaaacga gatattgcca gttttttaag acaaatgcac ggtttagatt
      601 atacagatat tagtgaatgt actattgata ataaacaaaa tgtattagaa gagtatatat
      661 tgttgcgtga aactatttat aatgatttaa ctgatataga aaaagattat atagaaagtt
      721 ttatggaaag actaaatgca acaacagttt ttgagggtaa aaagtgttta tgccataatg
      781 attttagttg taatcatcta ttgttagatg gcaataatag attaactgga ataattgatt
      841 ttggagattc tggaattata gatgaatatt gtgattttat atacttactt gaagatagtg
      901 aagaagaaat aggaacaaat tttggagaag atatattaag aatgtatgga aatatagata
      961 ttgagaaagc aaaagaatat caagatatag ttgaagaata ttatcctatt gaaactattg
     1021 tttatggaat taaaaatatt aaacaggaat ttatcgaaaa tggtagaaaa gaaatttata
     1081 aaaggactta taaagattga ttatataata tatgaaaagc tattataaaa gacattagta
     1141 ttaaatagtt taaaaaaatg aaaaataata aaggaagtga gtcaattcca gactcctgtg
     1201 taaaatgcta tacaatgttt ttaccatttc tacttatcaa aattgatgta ttttcttgaa
     1261 gaataaatcc attcatcatg taggtccata a
//
LOCUS       DASHXG010000157         1279 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.172, whole genome shotgun sequence.
ACCESSION   DASHXG010000157 DASHXG010000000
VERSION     DASHXG010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.172"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            15..284
                     /locus_tag="U2R59_002869"
     CDS             15..284
                     /locus_tag="U2R59_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967186.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            289..453
                     /locus_tag="U2R59_002870"
     CDS             289..453
                     /locus_tag="U2R59_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967187.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            446..748
                     /locus_tag="U2R59_002871"
     CDS             446..748
                     /locus_tag="U2R59_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967188.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            745..906
                     /locus_tag="U2R59_002872"
     CDS             745..906
                     /locus_tag="U2R59_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEM8967189.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            903..1208
                     /locus_tag="U2R59_002873"
     CDS             903..1208
                     /locus_tag="U2R59_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967190.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
BASE COUNT          491 a          197 c          312 g          279 t
ORIGIN      
        1 taagaggtgg gaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
       61 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
      121 tcgaaggaat taagaatgat cgttcgagtt ggagtaagct cagatactat ttcgcacttt
      181 atatcgatac aacacaatta agaaatttag catataccaa attactattt gttgattgtg
      241 ttaaaggctt gcaaaaacat cttaatgaac ttgagcaggt gtaatcagat ggacctaaag
      301 acatttacag cacagattga actaatgcat caagaagctt taagacaaag tgtatcgtac
      361 gaagacaagt ggctcaacac gttccacggc ggacgtgaga gcgcacttga tcaagtactc
      421 aaattactga aaggagaatg tcgggatgga taagaaagcg gcaatgcagc gaattatcga
      481 attgacttat tcagaagatt ggcaaaatga caaagaagct gcttcagaag tgatgaggct
      541 tggaagagcg atgtgggcag acaagagcaa caagccaaga ccacgaaaaa tcgcaatttg
      601 gcacggtgac aaacttctag tgatagggac agctgaacag ttagcaagtc tcacaggctt
      661 gcacgagaaa atcgtgagga aaagagcaag gtgtggctac acagacgcta agaagagaac
      721 gtttagatac gtggaggaat catcatgaca acagaagaag tgattcaaat gcgtattcga
      781 agccttcagc gtgagattga cgatctggaa cgaacaaagg cagtgatggt caatgaaacg
      841 gcgagaaagg caatcgattt gcacatagag aatttaagaa gggaaatcca tcgattggag
      901 gaatgagcgt ggataagaaa gcagcaatga aaagaattgc tgaattaacc aagtcagaat
      961 cttggcaaga agacaaagaa atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga
     1021 ctgaaaagcc caaacggaga acgccgagaa aaattgcaat ctggcatgat gaccgaattt
     1081 tagtaacagg tactgctgaa cagttatctg aaattactgg attaagcaaa aacattatct
     1141 gggatagagc taggagctta tggattgatt caaaaggacg acagtttagg tatgtggagg
     1201 agagataatg gatctcatta cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa
     1261 gattcagaaa gataaaaaa
//
LOCUS       DASHXG010000158         1196 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.173, whole genome shotgun sequence.
ACCESSION   DASHXG010000158 DASHXG010000000
VERSION     DASHXG010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.173"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1103
                     /locus_tag="U2R59_002874"
     CDS             <1..1103
                     /locus_tag="U2R59_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEM8967191.1"
                     /translation="WVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFIVRYADDFKIM
                     CSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKIKVIPKGRTKH
                     GYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQNYYCIATNVYN
                     NLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVMIADNPLLPIQ
                     GVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPADSVEFNDNRIS
                     AYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAKAILTESADEA
                     KSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
BASE COUNT          466 a          206 c          243 g          281 t
ORIGIN      
        1 ggtgggtaag cagtcagtgg gaaacattcc agccgaagaa ccgcagtaaa aatgggtggc
       61 ttcaatacgc aaagaaatat accaaactga aaagcggttt tattgtacgt tacgctgatg
      121 attttaaaat catgtgttca acctatggag aagcacaaag attttaccac agtaccgtag
      181 attttcttaa taaaaggctg aaattagaaa tcagtccaga gaaatcaaag gtagtaaatc
      241 tgaagaaaaa ttcatcagat tttctggggt tcaaaatcaa agtcattcca aaaggaagaa
      301 cgaaacacgg ttatgttgcc aaaacagata tgaaccaaaa agcattaaag aaagcgaaaa
      361 caaatctaaa gttaaaggta aaagatatag ccagacatac gactggcttc aatatcagca
      421 gatataatct gacagttatc ggtatgcaga attactactg catagcaact aacgtatata
      481 acaacctgac agaagtaagt tacgctctct taccgaccat acgaatccgt ttaaggaaca
      541 ttgcaaaatc agttccattt gaaagtacaa gttcagaatt tcagagcagg acaaaaggaa
      601 tcagaccaaa aacaaaaata gtgatgattg cggataatcc gctattgccg attcaaggag
      661 tacaacacaa aaatcctatg aatttctcgc aagatatttg taattttaca aagcaaggga
      721 gaaacaaggt gcatgaggac gttgtagttg taacaaaaga agaaatccga gcgttgttgg
      781 aaaatgaaaa ccctgccgat agcgtagagt ttaacgacaa tcgtatttcg gcatatatcg
      841 cacaacaagg caactgctat gtaatgaatc gtcgaggaac tccgtccact ctgatatgta
      901 ttcacaaatc agacaaagga gataaccttg acagatattc taatctggca tttgtggaaa
      961 ttcccattgc aaaggcaatc ctaacagaat cagcagacga agcaaaatca ctgttaaaag
     1021 gttatgttct taatagtcag cagaagaaaa aactgaacag aatacggacg aattacggat
     1081 accagacaat aactgggaaa taacttataa atctatttgg atatgatgga acgccgtatg
     1141 aagcgaaagt ttcatgtacg gtgtgaagcg ggggaaaact tggagataac atcaaa
//
LOCUS       DASHXG010000159         1196 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.174, whole genome shotgun sequence.
ACCESSION   DASHXG010000159 DASHXG010000000
VERSION     DASHXG010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.174"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(105..629)
                     /locus_tag="U2R59_002875"
     CDS             complement(105..629)
                     /locus_tag="U2R59_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEM8967192.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="U2R59_002876"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="U2R59_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEM8967193.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
BASE COUNT          313 a          301 c          173 g          409 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttt
//
LOCUS       DASHXG010000160         1194 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.175, whole genome shotgun sequence.
ACCESSION   DASHXG010000160 DASHXG010000000
VERSION     DASHXG010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.175"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..1076
                     /locus_tag="U2R59_002877"
     CDS             <1..1076
                     /locus_tag="U2R59_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEM8967194.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tctt
//
LOCUS       DASHXG010000161         1160 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.176, whole genome shotgun sequence.
ACCESSION   DASHXG010000161 DASHXG010000000
VERSION     DASHXG010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.176"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            14..1141
                     /locus_tag="U2R59_002878"
     CDS             14..1141
                     /locus_tag="U2R59_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8967195.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          419 a          200 c          224 g          317 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa
//
LOCUS       DASHXG010000162         1127 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.177, whole genome shotgun sequence.
ACCESSION   DASHXG010000162 DASHXG010000000
VERSION     DASHXG010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.177"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>1127)
                     /locus_tag="U2R59_002879"
     CDS             complement(<1..>1127)
                     /locus_tag="U2R59_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HEM8967196.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSVHTSCDDNGFILSTIITPRNIHDSQVAFQLV
                     KQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDE
                     YFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLNQCTISKNHQRVITRHVWG
                     DLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVF
                     AAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSL"
BASE COUNT          304 a          233 c          202 g          388 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc ggacaaatat aacaatcaaa atactcgtca
      481 tagagaaact cattttttga taatagctcc tttttccctt tgggccttga ataaggcaaa
      541 caaggtcgaa ggttcaaatg agtcaaaaag tgaacaaact taggtgtctt atacccagca
      601 tcagcgacaa cacaattgat ttcaggaaaa agtctcttcg attgtttgac gagctgaaag
      661 gcgacttgac tgtcatgaat atttctagga gtgatgattg tgctaagaat aaatccattg
      721 tcgtcgcatg aagtatggac agaataagca aattgttttt ctcgttcgcc tttgacgtag
      781 tagccgcttt ccggatcagc tttacttatt tttctttctt tcagcttcac ttccttttct
      841 aagtccaaag taaaagggcg ttttccagcc tctattcgtt gacgattgat ctcatcttct
      901 aattcatcct gataggcttt cgcttcatca tgggtcattt ctttcgtaaa cttatgttta
      961 ttggcgttag ctttgatgtg ggtagaatcc agatacaaat tatcctctgt tacaaaacct
     1021 gctttaactg cttgttctaa aatataggca aaaatatcct caaacaccgt cgtttctcta
     1081 aatcggcgaa cataattctt tccaaaagtt gagaaatggg ggatttt
//
LOCUS       DASHXG010000163         1061 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.178, whole genome shotgun sequence.
ACCESSION   DASHXG010000163 DASHXG010000000
VERSION     DASHXG010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.178"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(36..992)
                     /locus_tag="U2R59_002880"
     CDS             complement(36..992)
                     /locus_tag="U2R59_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967197.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DASHXG010000164         1045 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.179, whole genome shotgun sequence.
ACCESSION   DASHXG010000164 DASHXG010000000
VERSION     DASHXG010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.179"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="U2R59_002881"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="U2R59_002881"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HEM8967198.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DASHXG010000165         1016 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.180, whole genome shotgun sequence.
ACCESSION   DASHXG010000165 DASHXG010000000
VERSION     DASHXG010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.180"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..149
                     /locus_tag="U2R59_002882"
     CDS             <1..149
                     /locus_tag="U2R59_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HEM8967199.1"
                     /translation="FYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKVLM
                     GITA"
BASE COUNT          376 a          135 c          150 g          355 t
ORIGIN      
        1 aattttatca aagtctccgt acagcctctt ccacgattaa gggcatggag accattcgag
       61 gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg tctactgaaa
      121 tcaaggtatt aatgggaata acagcctaag atatttggag ttcagagagg gcgcgtttga
      181 ttttcaaact tcgcaacaga acccattagc aatatataaa agaaggtatc aagagtcaca
      241 gtgaatttat tccgaaaagt gaaaagagca aatataaaat ttaataaaaa taagaactaa
      301 ataggaaaac gtagacgtaa ttttctacgt tttccttttc atatatatta aatattacgg
      361 aaaattatat aaactaattt agtgttttgt ttgtaattcc taattttgct ccacttttag
      421 ataattttta ggtctattta actcattaga cattctatgc tcatttttct ccaaatttgt
      481 ttcaactctt tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga gtacttttat
      541 tacgatacta gtatgatata tatctacagc aaacagttaa aatcttccta aaataagcga
      601 atagcattcc taaaacctat aaaattttta gatgaagcga caagtggaca attaataaac
      661 tacttgaaca tgaaattatg gatcaccttt caaatttaga aaatggaatt cttatactta
      721 ttgcgcaaca tttattgatt gcaaaattat gtgacaaaaa gaactagtag aagaaggaat
      781 aatggcttga taataaagta ctacctatta aaggtagtac tttatttaat ttagtataaa
      841 ttaacatact actatatttt aggtttcata ttatataaat taataatata ctaccatttg
      901 ttggtagtat aatttaaagg taataagtta ttcttttatt actatgtttg ggttttatag
      961 caaagaaagt ttaataagag tttggaccta gcaaacaata ttaatgaggt cattaa
//
LOCUS       DASHXG010000166         1007 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.181, whole genome shotgun sequence.
ACCESSION   DASHXG010000166 DASHXG010000000
VERSION     DASHXG010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.181"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..144)
                     /locus_tag="U2R59_002883"
     CDS             complement(<1..144)
                     /locus_tag="U2R59_002883"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967200.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
     gene            complement(177..>1007)
                     /locus_tag="U2R59_002884"
     CDS             complement(177..>1007)
                     /locus_tag="U2R59_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEM8967201.1"
                     /translation="QGVAGVYGNPLLWFRMLSWIVITGISIVFTMLYASRVKKNPLSS
                     IVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIWGIISKGWYMVEISALF
                     LGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGVLVILEGGMIIDTILNS
                     LANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVMAPLGDLMNVSRDVVVL
                     SNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFAILTLVSAVLLYIATLF
                     "
BASE COUNT          369 a          206 c          170 g          262 t
ORIGIN      
        1 aaaagcatct atgaaaaaat gcggagcacc tccccaaagt tcaacagaag aaataccaat
       61 tttctgttga taagcgaaaa attctttgag agaataaaat aaatagtgga tattcattcc
      121 tgctaattga tttattttaa tcataactat tgcctcctat taatggatga ttaagactaa
      181 aagagtgtag caatgtataa caaaacagca gaaacaaggg ttaagatggc aaatattttg
      241 aagccaacct taaaccattt agagaaatta atctctgcga tggctaatcc tgccagtaat
      301 acaccactag ttggggagat aatattcatt aaaccatttc caaactggtt acttagaaca
      361 acaacatcac gacttacatt cattagatca cccaatggtg ccataaccgg catcgttaat
      421 gccgcagctc ctgaggagga tggaacaaaa aaggaaacaa ttacttgaga aatgagtaga
      481 atcgtagtga acaggaattt tggaagacca cctaaaaggt tagccaagct gtttagaata
      541 gtgtcaataa tcattccacc ttccaagatt accaagactc ctctagctag cccaatgatt
      601 acagcagcat aggcgaaatc tgaacagcct tcgacaaaag cttcagcaat ttccttttga
      661 gaaaatctag cgatgccccc agcaaaaaga cctaatccta agaatagtgc agaaatttca
      721 accatatacc atcccttgga aatgataccc caaatcatga ttcctaaacc tacgataaaa
      781 ccggcgataa ttagtttatc ttgtgttgaa aactcttttt cagtgtcaaa attttgaaac
      841 ttatgcttaa cctttaaatc actctcataa acaatagagg acagtggatt ctttttgact
      901 ctgctagcat aaagcatggt gaaaacaatt gaaatcccag taatgacaat ccaggatagc
      961 atccgaaacc aaagcagggg atttccgtaa acgccagcta ctccctg
//
LOCUS       DASHXG010000167         1003 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.182, whole genome shotgun sequence.
ACCESSION   DASHXG010000167 DASHXG010000000
VERSION     DASHXG010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.182"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>1003
                     /locus_tag="U2R59_002885"
     CDS             <1..>1003
                     /locus_tag="U2R59_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEM8967202.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          301 a          209 c          191 g          302 t
ORIGIN      
        1 ggcaagaaga tctctatgat tctcctgaat cgtagcggta ataaacggac ctatcttcgg
       61 ttgaagaaac agcgatacct ctgccgagca tgtaaaaaat attttaccgc tcggacgtat
      121 ctcgttaccc cattctgctt tatttctaag cagattcatt acaagatctt agaagaattg
      181 acagagcgtc aatctataaa agcaattggt aaacattgcg atgtttctgt gacaactgtt
      241 cagcggacat tgtccgcctt gtcatcagat atccgtcaga atcttgagta tttacctcgg
      301 tgtctattat tcgatgagtt tcgttctctt tctacatggc acggtaaatt ttctttttct
      361 tgtatggacg gtgagaccgg gaaactgttt gagatcttac ctagccgccg taaaaaagat
      421 ctcgttgctt ttttcatgcg tttttctctc aaagcgaggt tgggtgtaca ttacatcgta
      481 acggatatga acgctcctta tttctcacta gttaaagagt gttttccaaa tgcacaagtg
      541 atcgtcgatc ggtttcacat tgttcaacat ctgaaccgct tcttcgatgc ggttcgaaaa
      601 cgtgtgatga aaacacttga tcaaaaagac ccaatacaag ctaaacagta tcgccaattg
      661 aaatccttat tcaaattact tttaaaatca gaggatcgtt tagattacaa tacactaacg
      721 aaaagacgca atttcaattg gagactattg actgaaacag aagtagttga ccgccttcta
      781 aagatttctc ctgaacttaa aacagcttat cgttactacc aagacctgct tactgcgtat
      841 caggaaaaag atccagatac ttttttccag ctgcttcgag caatgcctgg agaagttcca
      901 ttggaactgc accatatcaa aaaagccttt ttcaaatacg agaaagggat tcggctggca
      961 ttactgaaga agtattcgaa tgcacgactg gaaaatctcc ata
//
LOCUS       DASHXG010000168         1000 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.183, whole genome shotgun sequence.
ACCESSION   DASHXG010000168 DASHXG010000000
VERSION     DASHXG010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.183"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(82..636)
                     /locus_tag="U2R59_002886"
     CDS             complement(82..636)
                     /locus_tag="U2R59_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEM8967203.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          186 c          107 g          383 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataatcatg aacttatata tatactctgt
      721 taaaagtgaa gaaaatcaag gggtttagtt tatgatttta tatcatttca gtaactcaga
      781 atattccgac ttttttgtac aaaaaaatta accttactta tatgaagatt ctaagctctt
      841 atttaaattt tagacgggca gttatccgta gaagttctta gaatagctaa tttacataat
      901 taaattatat gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga
      961 aataaattag catatgaata accgtgctac caaacttttc
//
LOCUS       DASHXG010000169         1000 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.184, whole genome shotgun sequence.
ACCESSION   DASHXG010000169 DASHXG010000000
VERSION     DASHXG010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.184"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            369..1000
                     /locus_tag="U2R59_002887"
                     /pseudo
     CDS             369..1000
                     /locus_tag="U2R59_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DASHXG010000170          991 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.185, whole genome shotgun sequence.
ACCESSION   DASHXG010000170 DASHXG010000000
VERSION     DASHXG010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.185"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(21..94)
                     /locus_tag="U2R59_002888"
     tRNA            complement(21..94)
                     /locus_tag="U2R59_002888"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="U2R59_002889"
     tRNA            complement(108..181)
                     /locus_tag="U2R59_002889"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="U2R59_002890"
     tRNA            complement(209..281)
                     /locus_tag="U2R59_002890"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="U2R59_002891"
     tRNA            complement(301..374)
                     /locus_tag="U2R59_002891"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="U2R59_002892"
     tRNA            complement(384..457)
                     /locus_tag="U2R59_002892"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="U2R59_002893"
     tRNA            complement(468..553)
                     /locus_tag="U2R59_002893"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="U2R59_002894"
     tRNA            complement(570..641)
                     /locus_tag="U2R59_002894"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="U2R59_002895"
     tRNA            complement(653..725)
                     /locus_tag="U2R59_002895"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="U2R59_002896"
     tRNA            complement(743..824)
                     /locus_tag="U2R59_002896"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="U2R59_002897"
     tRNA            complement(832..904)
                     /locus_tag="U2R59_002897"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="U2R59_002898"
     tRNA            complement(908..980)
                     /locus_tag="U2R59_002898"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DASHXG010000171          983 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.186, whole genome shotgun sequence.
ACCESSION   DASHXG010000171 DASHXG010000000
VERSION     DASHXG010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.186"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..378
                     /locus_tag="U2R59_002899"
     CDS             <1..378
                     /locus_tag="U2R59_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HEM8967204.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..>983
                     /locus_tag="U2R59_002900"
     CDS             426..>983
                     /locus_tag="U2R59_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEM8967205.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFN"
BASE COUNT          289 a          167 c          224 g          303 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aac
//
LOCUS       DASHXG010000172          959 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.187, whole genome shotgun sequence.
ACCESSION   DASHXG010000172 DASHXG010000000
VERSION     DASHXG010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.187"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            38..>959
                     /locus_tag="U2R59_002901"
     CDS             38..>959
                     /locus_tag="U2R59_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEM8967206.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFL"
BASE COUNT          343 a          173 c          184 g          259 t
ORIGIN      
        1 atagttccga cgaaagaatt ataaggagtg agtacaaatg acctataacc atcttacacc
       61 aactgaactc gtaatgatag aagcttattt caatcaatca caacctgttt caaaagtagc
      121 caatctgtta caacgttctc gacaaactat ttataaggtc tatcgttttc ttaaatctgg
      181 tggaagcgca atgagctact ataaacaata taagaaaaac aaacgtaact gcggaagaca
      241 tccgattgtt ttacctgatg agcaacagga atacattcaa aaaaaggttg ttcaagggtg
      301 ggctcctgat gtccttattg gtcgagcaga gtttcctatt gcttgttcgg tacgcacact
      361 gtatcgaatg tttaaagata aaacctttga cactcacgat ttaccaatga agggaaaaag
      421 aaaaccaaac ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt caatccgaga
      481 cagaaagaca gactataccc agtttgatca tgaatttggt cacctggaag gtgacactat
      541 cgtgggtgga aaacataaaa gcgcggtcat cacattagtt gaacggctat ctaaagtcat
      601 cattaccttg aaacccgaag gcagacaggc taaagacatt gaaaataggc tgaatcaatg
      661 gtttcgttgt gtcccaaaaa acttatttaa atccatcaca tttgattgtg gaaaagaatt
      721 ctcaaattgg aaaaagatta gtaataccaa cgatatttca atttattttg cggatccagg
      781 aacaccttct caacgaggat tgaatgaaca ttcaaatggc ttattacgta aagatggttt
      841 gtataaagct atggatttta atggtgtatc tgaaaccttt atccaatcgg tggcatcgaa
      901 acgaaatcat attcctagaa aatcattaca ctatcggaca ccaatggaag tatttttga
//
LOCUS       DASHXG010000173          935 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.188, whole genome shotgun sequence.
ACCESSION   DASHXG010000173 DASHXG010000000
VERSION     DASHXG010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.188"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(25..162)
                     /locus_tag="U2R59_002902"
     CDS             complement(25..162)
                     /locus_tag="U2R59_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HEM8967207.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(159..848)
                     /locus_tag="U2R59_002903"
     CDS             complement(159..848)
                     /locus_tag="U2R59_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEM8967208.1"
                     /translation="MKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGEL
                     LKADEKDGMGNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDR
                     AFHAIQDLLKGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQ
                     LTSEPKPYTIERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILE
                     QQSMAIENLII"
BASE COUNT          256 a          231 c          149 g          299 t
ORIGIN      
        1 aaattttgtc cgaaattcat cttgtcactt tcctttcttt tccattgctc gatccgctgc
       61 tgcacttgca ttcatcaagc acatcacagt aacaccaagc atactgccac caaataccaa
      121 aaaaatatct tttacaattc ccatgacgat tcctcttttc atataatcaa attttcaatt
      181 gccatacttt gttgctccaa aatcttttta tgtcggtctg ataagcgtgc attctgtacc
      241 atatcctgga tataggttgt ccgattcaat cgatccaact ccttagccat tttccacgta
      301 ggggcgactt gtcggcctag ccaattcaag gttcgttcaa tggtatacgg ttttggctcg
      361 gaagttaatt gaatctcttt ccgattccgt ccaataaaac gcccccattg ttcattcaag
      421 ggccagttgg ttcgcctttt accttctact ttatccgcaa atcgcaagta acgattgata
      481 atggaaaacg tggtgctctc aatgctacga ccttttaaca aatcttgaat cgcatgaaaa
      541 gcacggtcat ttttcagtcg aatctcaaaa cgatttttcg tctcagtttg gtctaatgga
      601 atccctaact tgatatattg ttcatagtct ttttcataca aacagaaata aacctcactc
      661 ttgagactgc cgatatataa ggtattgccc atgccgtcct tttcatcagc ctttaaaagt
      721 tccccggaac gataactttt aaaggtacga aacaaggaga tacattcttc cttctgacat
      781 tttttcgtta gctcaggtat atccaatagc cccactcgat cattgattgc caagtccaag
      841 cgtttcatca cgccaccggc ctttagacaa tcctcgaaaa agtcgtacca gctacgcttt
      901 tgagcgagta aaaaagtttc aaattgtcgg caacc
//
LOCUS       DASHXG010000174          876 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.189, whole genome shotgun sequence.
ACCESSION   DASHXG010000174 DASHXG010000000
VERSION     DASHXG010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.189"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..434)
                     /locus_tag="U2R59_002904"
     CDS             complement(<1..434)
                     /locus_tag="U2R59_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8967209.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="U2R59_002905"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="U2R59_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HEM8967210.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          263 a          143 c          137 g          333 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat atcaactcat ttcttg
//
LOCUS       DASHXG010000175          829 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.190, whole genome shotgun sequence.
ACCESSION   DASHXG010000175 DASHXG010000000
VERSION     DASHXG010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.190"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..720
                     /locus_tag="U2R59_002906"
     CDS             <1..720
                     /locus_tag="U2R59_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEM8967211.1"
                     /translation="GKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFT
                     NRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVY
                     LANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITL
                     EEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNK
                     VQLIRLNKYRVLAGNQELNLI"
BASE COUNT          319 a          128 c          165 g          217 t
ORIGIN      
        1 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
       61 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
      121 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
      181 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
      241 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
      301 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
      361 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
      421 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
      481 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
      541 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
      601 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
      661 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
      721 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
      781 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatca
//
LOCUS       DASHXG010000176          771 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.191, whole genome shotgun sequence.
ACCESSION   DASHXG010000176 DASHXG010000000
VERSION     DASHXG010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.191"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..660
                     /locus_tag="U2R59_002907"
     CDS             <1..660
                     /locus_tag="U2R59_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8967212.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          285 a          118 c          143 g          225 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc a
//
LOCUS       DASHXG010000177          761 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.192, whole genome shotgun sequence.
ACCESSION   DASHXG010000177 DASHXG010000000
VERSION     DASHXG010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.192"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            51..731
                     /locus_tag="U2R59_002908"
     CDS             51..731
                     /locus_tag="U2R59_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HEM8967213.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          270 a          127 c          152 g          212 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      661 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
      721 tcccagctta aatcatagat accgtaaggg attttattct t
//
LOCUS       DASHXG010000178          744 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.193, whole genome shotgun sequence.
ACCESSION   DASHXG010000178 DASHXG010000000
VERSION     DASHXG010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.193"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            178..381
                     /locus_tag="U2R59_002909"
     CDS             178..381
                     /locus_tag="U2R59_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HEM8967214.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            381..731
                     /locus_tag="U2R59_002910"
     CDS             381..731
                     /locus_tag="U2R59_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEM8967215.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          300 a           80 c          120 g          244 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgtcaatc
       61 attgttatat aataaaatgt tatataataa aattactaat gatatttaat attacaagca
      121 atcttaagaa attcgaaaag gaaaaaatga ttatgaaaaa gaaagaaaaa gaaagtattg
      181 aaacattgtg ttattctagg aatattagga acttgtctag ctggcattgg tacaggaata
      241 gacgttgacg cagctactta ctatggaaat ggtctttatt gtaacaaaga aaaatgttgg
      301 gtaaattggg gacaatcatg gtcagaaggg ttaaaacgtt ggggagataa tctttttggt
      361 agttttagtg gaggacgata atgacttcaa taaacattga tcacacaaaa aaagtcatac
      421 atgaattata caatagttta atgacacgac ctaatcagac gaaagcatta ttagatatta
      481 ctgatgtttt atttcaggta tataaaaaaa ttgatacagc aaaatatcct gaaattcttg
      541 taaataaatt agttaattat atttacatcg tgggttttga taataaaata cgctttattg
      601 ataatgatga aaaattatta atagaattag gggatatttc taaaaaagct ggaattaata
      661 gtaaatacaa agcaaacttt acagataaat cgcaatttta tagttattca gaaacaatgc
      721 ctcaacgata aaatatagta tact
//
LOCUS       DASHXG010000179          720 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.194, whole genome shotgun sequence.
ACCESSION   DASHXG010000179 DASHXG010000000
VERSION     DASHXG010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.194"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            145..402
                     /locus_tag="U2R59_002911"
     CDS             145..402
                     /locus_tag="U2R59_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967216.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(634..>720)
                     /locus_tag="U2R59_002912"
     CDS             complement(634..>720)
                     /locus_tag="U2R59_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEM8967217.1"
                     /translation="DEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          289 a           86 c           97 g          248 t
ORIGIN      
        1 atttttctgt ccacgttcat tttactccaa agttttcctc atttcaaaag aaaatcacag
       61 aatacacgaa gaagcgtttc tatttgtata aactatatca aagttctata cttaaattat
      121 caaataaaaa ggacgtgaag ataaatgtca aatttagaaa acaaagaaga aaaagttgta
      181 aacaaaattg tttctgttgt caataaactg gataaagagt tagacgaact tgatacgtta
      241 tctgaaaatc cagaaaaaaa acataaccta aaaaaatggt tagttgaacg aaaggctatt
      301 catgaaatta aaaaagttct tcatgaagct gataaatatg aaaaatatga tgaaaaagaa
      361 cttgataaag aatttaaaga aatcaatgac ttattactat aattgattta tacgactcat
      421 ttttgagtcg tcagactgca aacaacactc taaatttagg agtttgtcta cagtctgaat
      481 agattttaaa tttattgtcc ataatgttat tatgaattta tagcattaag aaaagagata
      541 agactttaca tttttttagg aatgtaaagt cttatctctt ttcttaattg tacaattagt
      601 attatctgca ctactttcta attaaataaa tttttagtta ttaacttgat taaaatcaga
      661 gataatatca tttaattcag tttgaagggt tgtaacgatt aaatggaaat tttcttcatc
//
LOCUS       DASHXG010000180          614 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.195, whole genome shotgun sequence.
ACCESSION   DASHXG010000180 DASHXG010000000
VERSION     DASHXG010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.195"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(175..>614)
                     /locus_tag="U2R59_002913"
     CDS             complement(175..>614)
                     /locus_tag="U2R59_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEM8967218.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT          177 a          121 c          136 g          180 t
ORIGIN      
        1 ttcttggagt taaacgcttc tgtcccagcc tcttttccta cgattagtca agtaaaaggt
       61 gcaagaaaaa tagctcgtaa acgaaagcga caaaatcaaa gcacaccaaa taaagccccg
      121 ttcgtaaaaa attttcgatc tgggcaaaga agtggtatac tgtaagtggt ttagttaatg
      181 gtccactgag accgcgtacg catagtcgta ctctgtatgt gccctaacca tagcgtgcat
      241 acatttcaga agcttgttca tacaagcaac tgtggcaacc ttatctttct tagggatagg
      301 ttgctttttt aatttgtagt aataatcgac aatatgatta ggagctgcgc gttgctggcg
      361 aatcatattt cgaatggtga agaaaataat tttccgtgct ttgggattac cacgcttatt
      421 gatgcggtct tggccagtat acttacctga atgataccgt cggatgtcga ttccgacaaa
      481 ggcattcaat tgtttatggg ttttaaatcg tgtgatatct cctaattcac cgagcaataa
      541 agcggctgtg agtgcgccaa tcccagggaa cgtttggtac aacaaaaagc aaggagagcc
      601 ttcggctttt ttga
//
LOCUS       DASHXG010000181          594 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.196, whole genome shotgun sequence.
ACCESSION   DASHXG010000181 DASHXG010000000
VERSION     DASHXG010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.196"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          239 a           80 c           70 g          205 t
ORIGIN      
        1 tgggtatagg tcatttgtac tcactcctta taattctttc gacggaacta ttttgagtgt
       61 agcacaaatg acttttttag ttgtctagct taattttaca atcggcgaag gtaaaaaaat
      121 aaaaaaatgt gacaagtgtt ttgaatcagc tgtggtaaag tttcctcaat ttaaactaaa
      181 tccagctgcc tcgatacaat ttcaaggaca tgtatttgat gttttagcta aagataacat
      241 aaaaaaatac aaaaaaggta atatattcca tattgatata caaatatctt ctaatttaga
      301 agatataaaa aaagccttta aaattaaaac aattggcact gctcctaatt ttaaataaca
      361 aaaaaattac tagataatct aaaaacagga tggcattatg agaacaataa ctaaacttcc
      421 tatatcacat attttgtaat tagtgaaaag caaattgact actatcataa gttaatgact
      481 ctcatcttaa tatttaaaat atattcatat ttttctattt tatctaaatg cgattttcat
      541 atctaataat agaaaaataa acaattaaca ataaaaaagt cttcatttat tgtt
//
LOCUS       DASHXG010000182          573 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.197, whole genome shotgun sequence.
ACCESSION   DASHXG010000182 DASHXG010000000
VERSION     DASHXG010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.197"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
BASE COUNT          185 a           81 c           81 g          226 t
ORIGIN      
        1 tttttcttga tgtgatatcc ttgtcttttt tgtaatgttt ttaacttatt gcttttgcaa
       61 aatttattta cctgttttct ggatcaacga tagtgtacat tatgctatcc ttgtttggat
      121 tttaggacgt ttaaagaggc acttttttac ataacttaat ccatagacct tttaagcatg
      181 ctgtgagata ataataaaga agagtttaaa gcgcacccca aaccacttcc ccataagtgt
      241 attacgcttt aaactctttt atatttgaat tcactaagaa gcataccata tttttgaaaa
      301 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      361 aggactgata ctatagatta caaatagtat cgtatttcgc aatcttaaaa ttatcttctt
      421 actgtgaata agataataaa atttgtattt gtccttttta ggtaacttat tttaatctat
      481 atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat ggtaactatg
      541 cactgtaacg ataatgctgc taaaatatct ttt
//
LOCUS       DASHXG010000183          531 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.198, whole genome shotgun sequence.
ACCESSION   DASHXG010000183 DASHXG010000000
VERSION     DASHXG010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.198"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            313..429
                     /locus_tag="U2R59_002914"
     CDS             313..429
                     /locus_tag="U2R59_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEM8967219.1"
                     /translation="MIGLNAISAKYCKFKAFVEKFTERQTDKIIQYHITYTD"
BASE COUNT          225 a           50 c           69 g          187 t
ORIGIN      
        1 ataataaaga attgaacttc tgagaaaaca aagaatcttt tttctttttt tgaattgact
       61 catggattgg cgttaaaatt ttattttgaa aaagttattt ctggtttaac tcaaaaaaag
      121 agatatgaat ctaatagtga tagaaaggat gttatttttc atgaaatggt tgttttagat
      181 ttaatacata taactaataa atgctattga atgtatttaa actaattaac aaaagaattt
      241 gaattgttaa taaaatccaa taaaatatat taataaagta gatagaaata aaaaaacaaa
      301 gactaaacat atataattgg attaaacgca atatctgcaa aatattgtaa atttaaagcc
      361 tttgtagaaa aatttactga aagacaaact gataagatta ttcagtatca tattacctat
      421 actgattaaa attttttgaa acgggatact aaataaaaaa tttatttata acagaactaa
      481 ttatttaatg cggatgcgcc aatacttggt cctgcaagag ctatttattt t
//
LOCUS       DASHXG010000184          529 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.199, whole genome shotgun sequence.
ACCESSION   DASHXG010000184 DASHXG010000000
VERSION     DASHXG010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.199"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            33..>529
                     /locus_tag="U2R59_002915"
     CDS             33..>529
                     /locus_tag="U2R59_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HEM8967220.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          194 a           98 c           87 g          150 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat
      481 ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DASHXG010000185          526 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.200, whole genome shotgun sequence.
ACCESSION   DASHXG010000185 DASHXG010000000
VERSION     DASHXG010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.200"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>526
                     /locus_tag="U2R59_002916"
     CDS             <1..>526
                     /locus_tag="U2R59_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEM8967221.1"
                     /translation="IRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIK
                     GRKIYLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQY
                     QMPQYQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLN
                     EYIRWYNNKRIKLK"
BASE COUNT          229 a           63 c           86 g          148 t
ORIGIN      
        1 aaatccgaat aaagcgatat aaatcttata aaggaacagt aggaaaaatt gccaagaatg
       61 tgttaaaacg aaatttttca gtagatacac ccaataaaaa atgggtgaca gacgtcactg
      121 aattcaagat aaaaggaaga aaaatctatc tatctcctat acttgattta tttaacggag
      181 aaataattag ttatagtata tcaactagtc caacatataa actgattgaa gaaatgcttc
      241 aacaagcaat taaaaaaaag ggaactgagg gttcactgat tctacattca gatcaaggat
      301 ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga gaataacatt attcaaagca
      361 tgtctagaaa aggaaattgc ttagataatt ctgtaataga aaattttttt ggtgtgctta
      421 aatcagagtt tttttatcga gaaaaattcc gatcaattga gatatttcaa agtaaattaa
      481 atgagtatat taggtggtat aataacaaaa ggataaaact aaagtt
//
LOCUS       DASHXG010000186          516 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.201, whole genome shotgun sequence.
ACCESSION   DASHXG010000186 DASHXG010000000
VERSION     DASHXG010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.201"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>516
                     /locus_tag="U2R59_002917"
     CDS             <1..>516
                     /locus_tag="U2R59_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEM8967222.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSN"
BASE COUNT          192 a           80 c           89 g          155 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttcta ccggtcaaaa atttgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaat
//
LOCUS       DASHXG010000187          514 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.202, whole genome shotgun sequence.
ACCESSION   DASHXG010000187 DASHXG010000000
VERSION     DASHXG010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.202"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(107..>514)
                     /locus_tag="U2R59_002918"
     CDS             complement(107..>514)
                     /locus_tag="U2R59_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HEM8967223.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          103 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttcc
//
LOCUS       DASHXG010000188          511 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.203, whole genome shotgun sequence.
ACCESSION   DASHXG010000188 DASHXG010000000
VERSION     DASHXG010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.203"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..>511
                     /locus_tag="U2R59_002919"
     CDS             <1..>511
                     /locus_tag="U2R59_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HEM8967224.1"
                     /translation="IRSRKAYGSRKIKKALSKRGIQISRRKISRIMKNRGLKSSYTVA
                     YFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREI
                     LGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLS
                     HKGCPFDNAV"
BASE COUNT          185 a           88 c           96 g          142 t
ORIGIN      
        1 tatccgcagc cgaaaggcct acggctcaag aaaaataaaa aaagccttat caaaacgagg
       61 cattcagatc agccgacgaa aaattagtag aatcatgaaa aatagaggat taaaatcgag
      121 ctatactgtt gcttatttta aagtacatca ttctacttgc aatgaagcca aaacgacaaa
      181 cgtattgaat cgtaaattct taagagacaa cccattagaa gcgatcgtaa cagacttgac
      241 ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc attttggatc tgttcaatcg
      301 agaaattctc ggctattctt gtggagaaca taaagatgcc gttctagtaa aaaaagcatt
      361 tagccgtatc aaacaacctc tgacagaggt tgagattttt catactgatc gtggaaaaga
      421 gtttgataac caagctattg atgaattatt aacaactttt gacatcaatc gatcattgag
      481 tcataaaggc tgtccttttg ataatgccgt a
//
LOCUS       DASHXG010000189          487 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.204, whole genome shotgun sequence.
ACCESSION   DASHXG010000189 DASHXG010000000
VERSION     DASHXG010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.204"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..>487)
                     /locus_tag="U2R59_002920"
     CDS             complement(<1..>487)
                     /locus_tag="U2R59_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEM8967225.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DASHXG010000190          480 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.denovo.205, whole genome shotgun sequence.
ACCESSION   DASHXG010000190 DASHXG010000000
VERSION     DASHXG010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.denovo.205"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..448)
                     /locus_tag="U2R59_002921"
     CDS             complement(<1..448)
                     /locus_tag="U2R59_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8967226.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
BASE COUNT          136 a           94 c           61 g          189 t
ORIGIN      
        1 tttttaaata tgcgttctct gctcttaaac gaataacttc ttcttcaaga gactcatctt
       61 taagtttttt aggaatgttt agcttggaat tcatactaat ttttctgccc cttttttggc
      121 tctcaagtga agaagcaccg ccttcttcat attgctctat ccatttactt agagttctat
      181 ttgaaccgat attaaatttt ttagcagttt cttggataga aagaccattt gtttccatat
      241 attctataac atcaagttta aattttgtag tgtagctttt gccacctcca accaagcctt
      301 cccaaccatg atagttataa atccttaccc aatgtctaac cagtgtacga tttatttgat
      361 atttatgtgc aagatatttg tagccgcctt cgttatttaa atagtctgaa actacttttt
      421 tcttaaaaac aaatgtatat ttccgcaaaa aaagcacccc ttttaattag atttctagtc
//
LOCUS       DASHXG010000191        20985 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.045, whole genome shotgun sequence.
ACCESSION   DASHXG010000191 DASHXG010000000
VERSION     DASHXG010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.045"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(134..577)
                     /locus_tag="U2R59_002922"
     CDS             complement(134..577)
                     /locus_tag="U2R59_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HEM8967227.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="U2R59_002923"
     CDS             complement(795..2135)
                     /locus_tag="U2R59_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8967228.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="U2R59_002924"
     CDS             2404..3300
                     /locus_tag="U2R59_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HEM8967229.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="U2R59_002925"
     CDS             complement(3450..4391)
                     /locus_tag="U2R59_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEM8967230.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="U2R59_002926"
     CDS             4517..5638
                     /locus_tag="U2R59_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEM8967231.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="U2R59_002927"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="U2R59_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HEM8967232.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="U2R59_002928"
     CDS             7426..7992
                     /locus_tag="U2R59_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEM8967233.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="U2R59_002929"
     CDS             8203..9264
                     /locus_tag="U2R59_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEM8967234.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="U2R59_002930"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="U2R59_002930"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HEM8967235.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="U2R59_002931"
     CDS             10177..12159
                     /locus_tag="U2R59_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEM8967236.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="U2R59_002932"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="U2R59_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEM8967237.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="U2R59_002933"
     CDS             12881..14305
                     /locus_tag="U2R59_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEM8967238.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="U2R59_002934"
     CDS             complement(14486..15259)
                     /locus_tag="U2R59_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEM8967239.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="U2R59_002935"
     CDS             complement(15256..16161)
                     /locus_tag="U2R59_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEM8967240.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="U2R59_002936"
     CDS             complement(16315..16635)
                     /locus_tag="U2R59_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HEM8967241.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="U2R59_002937"
     CDS             17109..17795
                     /locus_tag="U2R59_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEM8967242.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="U2R59_002938"
     CDS             17797..18741
                     /locus_tag="U2R59_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEM8967243.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="U2R59_002939"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="U2R59_002939"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEM8967244.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="U2R59_002940"
     CDS             19663..20940
                     /locus_tag="U2R59_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967245.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6778 a         3784 c         4362 g         6061 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DASHXG010000192        13610 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.064, whole genome shotgun sequence.
ACCESSION   DASHXG010000192 DASHXG010000000
VERSION     DASHXG010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.064"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(<1..456)
                     /locus_tag="U2R59_002941"
     CDS             complement(<1..456)
                     /locus_tag="U2R59_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEM8967246.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPF"
     gene            complement(449..1588)
                     /locus_tag="U2R59_002942"
     CDS             complement(449..1588)
                     /locus_tag="U2R59_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEM8967247.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            complement(1793..2986)
                     /locus_tag="U2R59_002943"
     CDS             complement(1793..2986)
                     /locus_tag="U2R59_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEM8967248.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(3065..3271)
                     /locus_tag="U2R59_002944"
     CDS             complement(3065..3271)
                     /locus_tag="U2R59_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEM8967249.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(3264..4406)
                     /locus_tag="U2R59_002945"
     CDS             complement(3264..4406)
                     /locus_tag="U2R59_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEM8967250.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            4918..5553
                     /locus_tag="U2R59_002946"
     CDS             4918..5553
                     /locus_tag="U2R59_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967251.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            5895..6530
                     /locus_tag="U2R59_002947"
     CDS             5895..6530
                     /locus_tag="U2R59_002947"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8967252.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            6637..7875
                     /locus_tag="U2R59_002948"
     CDS             6637..7875
                     /locus_tag="U2R59_002948"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8967253.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            8102..8521
                     /locus_tag="U2R59_002949"
     CDS             8102..8521
                     /locus_tag="U2R59_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEM8967254.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            8526..8765
                     /locus_tag="U2R59_002950"
     CDS             8526..8765
                     /locus_tag="U2R59_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEM8967255.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(8990..9913)
                     /locus_tag="U2R59_002951"
     CDS             complement(8990..9913)
                     /locus_tag="U2R59_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEM8967256.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(9945..10709)
                     /gene="map"
                     /locus_tag="U2R59_002952"
     CDS             complement(9945..10709)
                     /gene="map"
                     /locus_tag="U2R59_002952"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HEM8967257.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            10867..11307
                     /locus_tag="U2R59_002953"
     CDS             10867..11307
                     /locus_tag="U2R59_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEM8967258.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            complement(11485..12054)
                     /locus_tag="U2R59_002954"
     CDS             complement(11485..12054)
                     /locus_tag="U2R59_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEM8967259.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            12309..13541
                     /locus_tag="U2R59_002955"
     CDS             12309..13541
                     /locus_tag="U2R59_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEM8967260.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
BASE COUNT         4220 a         2502 c         2532 g         4356 t
ORIGIN      
        1 gaaaggcaca aagcgcaaaa cgtaatcaaa aacagccagc tgctcacgga tgaggtgctg
       61 agttgttcca tcttcattaa gaatcttagg tgctaacatc gcacattccg gatgttcttt
      121 caataacaag accaatgctg taactgtctc ttcatccact aaaatatctg ggttacaaat
      181 aatgccatag cgagaatcgc tagctatcag attgtgatta tgtccataac caaatccgga
      241 attttcatca tgaaaataga tatcgatgta gggatatttc ctatactctg ttagtctttt
      301 tttgtactcg ggaagtgaat tgttgtcaaa aattcggatt tttactgctg tttcatcttt
      361 tacagttgaa ataaaattat ctagtgtccg aaaaatttta tcactgtttg ccgtcacaat
      421 actaataagg atcggctggt ttaatttgtt attcatctat atgacggttc catttcttca
      481 aatatttctg ttttacttgc gtacggtact ctttattccc taaaaatcgc aatgttttta
      541 aaataaactg atgtttctca ttgatcagac caatcaattc aaataataaa attgcagcaa
      601 acaacatggc aataatcaat atgatcgttc cgattcttcc agtataattc atgaccatag
      661 ctgtgaaaga aaacatcaaa gccatcgcat aaatcgtcag gacagcacct ttatgagtaa
      721 agcctaaact gattagtcgg tgatgaagat gttttttatc tgctgtagaa aaagaaacac
      781 ggtttgcttt tctcctaatg atagcaaaaa acgtgtctgt taccggcact cccatgacga
      841 tcagcaaaga aatcgatgaa acaaaagtca cgttcttcag cccttgtagt gaaaggacgg
      901 ccatcataaa ccctaggaat agagctcctg tatcgcctaa ataaatcttt gccggataaa
      961 aattgtaagg aaaaaaaccg ataatacttg ctacaagaca gaaaataaca actggaatat
     1021 acactgtaga agcatggagg aaaaaatatc caatgattcc tatcgtaatt aaaccgatca
     1081 atgaaatccc tgccgccagc ccatccaaac cgtcaatcag attgaccgca ttcgtgatac
     1141 cgaagatcca aaaaatcgtt acgggaaaac taagccagcc tagttggata tatccaataa
     1201 aaggaagcgt gaaggaatca atacgtatat ctgctacaaa ataaataata agagaagcaa
     1261 tcaagatccc tatacttttt tgtttaggtg tcagctcata tttatcatcg agcactcctg
     1321 tgactatgat tactaaagaa gcaatcaaga tcggtacaat atacgattga gggataattt
     1381 tacggaataa gaataaagtc gatataacaa atgaaataaa gataggcagt ccgcccgctg
     1441 aaggcattgg aactttattt attcttcttt catttggttt gtcgaccata cctgtttgta
     1501 ctgaaatgat tttgaataca ggtgttaata tcagtgataa taaaattgtc agaaaaaatc
     1561 ttataaccat actaaaagaa acaagcatat gggcacctac tttaattaag agtcataatt
     1621 attataaatt atatatgtct ttttgactat ctttttatat cttctcaaat gtccgcaaag
     1681 ccttatttta tcggctctac gggcattttg cttttgtggt aaacctcgca tatctaggtc
     1741 tatcttctta tattttccct gtcaatcgtg gttaaaatcg tggtaaatac ttctatgcga
     1801 ttagacgctg aacctctgat tttgcggtat ctatggacgc atgagcgtac cagttcattg
     1861 tgatactgat gtttgaatgc cccatgatat actgtaaatc tttcgggttc atgttcttgc
     1921 ttgccagcct tgtgcagaat gtatggcgta gcgtatgcgg tgtaatatgt ggcaagggat
     1981 tgtccttgtg gtgcttgttg tatttcttta ccatacggat aaataaggcg ttataatcaa
     2041 tggcaacttt tggattacct ttcggattga taaacacaaa accgctgtgt ccgtctacct
     2101 ctatcgactt tatctttggt cggctgttga taacccgttg aaatgcctgt atcgtttctt
     2161 tgcttaatgg cacttgcctt atcccgcttt tcgtcttagg cgtttcaata taatagccct
     2221 gttccttact ctttagtaac tggtggtcga taatcacaac ttcattcttg aaatcaatgt
     2281 cggctactgt cagtccgcac agttccgaga tacgaagtcc tgtctttaac agtatcagca
     2341 catcatcata atgcttgtga tacacgttgt ccgtcttaat aaatgacaat aaggcttgct
     2401 cctgttcctc tgtcaatgcg actttctctt tggtatcatt ttctatgact tcacttagct
     2461 tgaaatcaaa agggtttttc ctcacataat catcttgtat ggctatgtag aatgacgctt
     2521 ttaacgagcg tttatggttg ttaatggtat tgtaggaaaa gcctttgtct ttcatgcgta
     2581 acgcccattc tttagcgtca gagggtttta tcgtatcaat gctcctagca cctaacttgt
     2641 cctcttttaa taaccgcatg agttgttccc gttgtttctg tgtgcttttc ttcacatttg
     2701 tcctctgtgc gttctgtttg gcatagagtt ggcaaagcgt cattttcttg cctgtgctgt
     2761 cgataccgtc ctcaatatcc cgtcttatct gctgttccag ttctcgaagt gagggttttt
     2821 cccgttttcc ctttggtgtc gggtctgtgg gtgtcaatct ccaagcatac acatattttg
     2881 tgtttcccaa tgcgtctaca tatttatata agtattttcc gtctgttcgt tggctctctc
     2941 cagtatgcag gatacgacct ttgttatccc gtcttttttc tttcatggtg tctgctcctt
     3001 tccttgttgg aaagagcctt gatatgactt gtgttcatca taacacatac aaggctcatt
     3061 tgcattagat tgcgtccaat ttatcaataa ccttttcaaa ctgtcggcgt ttaatctgta
     3121 tgcggttgcc attcataatg agccagccag cgtccttgtt ttcctctgcc aatcgtctta
     3181 acttgttttc tccaatgcgg aaatactttg acgcttcttc aatggtaagg gtgtattttt
     3241 cccatacggg aatatcctgt gtattactca taaaacaccc cctcactttc gattacgtct
     3301 gatatgtccg tacacatctg ttccacaagc atttcctgtt tttcagaaag gtgggtacat
     3361 tcatcaatca ttttcatgta gtttgaacct gtcagcctgt cgatttcctc tatcatcacg
     3421 attgacggca tgacctgtct ttccagccat tgcagagtgc gttccatatt gacaggtaca
     3481 gggttcattt caaaaggtaa actgtcatgg gaaatgaata tctcccacaa tggatagtca
     3541 ggaaattcca caaaatcggt aatgagataa aacaccagcc catgagggtt atacgtcaat
     3601 aacagttctt caactgcctg taccgccttt ttgtcacgca gacgaatttc aaaacggttg
     3661 ataatatcgg tatgtttctt tttcgttgcc tgttcctttt gtttttcata caggcagaaa
     3721 tattttgtgc ttgcctttga gccgatataa agggtacttg ctaaattacg gttttttccg
     3781 cttaattttc caccttgtac attttcatag tttttacagc gacattccgc accaccattt
     3841 ctgtattttt cagatagcac aggaatatcc agcagaccgc acatatcatt gattgccaag
     3901 tcaaaacgtc ggataacacc gccacagtca agacagcggt ttaagaatga ataccagtcc
     3961 ctgttctgtg cctgtaagac atattccatg ttgcgtgagc ctgccccttt taattctaaa
     4021 aatacgccca tgtgttcatc atcagaagcc atgaccttga tttccccgta agcataatgc
     4081 tccttatagc cataataccc atagtcataa tggataaaat aatctgcttt catgccaagc
     4141 acctttcgga taacttccaa tgcgtcagtc gttggaaaac ggacagacag ataatcaacg
     4201 agcagataaa aaggcttatc gcagatatag taattcagac aacgcaggat aatgttctgt
     4261 gtttccttgc tggcgttagc ttttccgttc tcaaagcggt tgatactata tcttgataca
     4321 tgggtaagac ttgcaagttc tccttgtgaa agaccgctgg caagacgttt gttcttcatt
     4381 tcaagtgcaa attctaaatt gttcattgta ttcctccaat cccacaatag ccttgaaata
     4441 cctgtaaacc acctttcaaa aagtgtgata tgtactatct tcttaaaacc tctcattact
     4501 actcacaggt ttgggggtgt atggtttttg acttgtcttt tgtgaaatag tgcccccctg
     4561 ttagataacg ggggcacaga caaggctcgc aggctcgcca gccgacaaag catttcttcc
     4621 ccttgacaca aggtgtcatg gcggtaagcc tgagaggctt ccgccaccgt gtcagaaata
     4681 ctttgtcagc aagttctgtt ttgccttttc taacaagttc catttcaacc gatattcata
     4741 tctacggatt taatcagata ggtatttctt tttgaatgtt tttatatttc attctattgt
     4801 gcttattcga ttacaagaac atagtaattc ttatatgctt atttgtcaat atcttttttt
     4861 gcctttacaa atcatattaa gcatgataga cttataatag cgaagatata acgagatatg
     4921 gagggttatg caatgaaaat aagccattta ggaaataata tacagaccat aagaaaattt
     4981 aggggaatga aacaacagga acttgcggac aaaatcggta tcaatatgca gagcctttcc
     5041 aagattgaaa gagggttgaa ctatcctgcc tatgaaacgc tggaaaagat aatggaagtg
     5101 ctggacgtta cgcccaatga attgttgtcg ggagaatgga agtatgtcaa tcaatctgaa
     5161 aaggaagtct gtcagttttt aagagccgaa gaacgtctaa atgcagaact gaaacatgga
     5221 cactatgata acttctttga cagcgaggaa gaatggctgg aatatgagtt agaaaagtta
     5281 cgggaatata ttacagacta tatcaacggg aaaagcattg aagcgtccga cctttaccca
     5341 atcaaagaat ttatccagca tttgaagttt caaaaattat tagaccgcta tgatgattta
     5401 tacagtatgg atatgtttgg ggaaagcata gagggacata agtataagac accttatcaa
     5461 gtcgtgaaaa tgataaaccc gaactcaaaa gaagatatgg aactgttacg agaagtatta
     5521 aggaataaca attttgatga tgaggacgag taactttttt cctcttgcga gaagatacag
     5581 caaacaaaaa gcccgatcaa gagtgcaaag caccaccaat ggtggcaaag ctcttgacag
     5641 ggctttttct tttctgttgt gggcaatcaa gaggaagaaa gggataaaat ctgatttgtg
     5701 gtaaatcagg caaaggcaac gcaggtatca cagtatgaat tgacaccgca taaggaaagc
     5761 aactggaaga ttgtagaata aatgaaaaag gcttgcattc tgcattttta taaaattgca
     5821 agtctttata ttgacaagca taaaatacta agatatactt taatcagacc aacggtttgt
     5881 attggaggta agttatggca cgaaataaat atccagaaga aacagtaaaa ctcattttag
     5941 atgtttctac aaaaatgttt tgtgaaaaag gatatgataa cacatcattg caagatatta
     6001 tcaatgaaac aaaactttct aaaggtgcta tttatcatca tttcgattca aaggaagata
     6061 ttttaaaagc aatttttcaa agaattggaa atgaaaatgc agtaatattt gctaaaatta
     6121 gagataacga tagtttaaac ggtttagaaa agttaagaga aatatttaag acagcggtat
     6181 tcaattctaa ccaaagcgtt ttattgacag tttctcctca actattaaac aatcctcgtt
     6241 ttcttgctat gcaaatagaa caaatgtatg aaattgtagt acctgaattt gttgaacccg
     6301 ttttagaaca aggtatcaag gataagtctt tggagattga aaattcacat gaaattgcag
     6361 aagttatcat ggtattaagt aatgtatggc tcaacccatt agttgaaatg acggataaag
     6421 agggtatgga aaaacgttgc aatacattca atgccctttt aaatggaata ggcatagaca
     6481 cattattaga cgaagaaaca atttctgcat ttatacagtt ttgtaaataa ctgtatttgt
     6541 tatccctata cgatagactg ctctataaaa gagcagttta tttaaaccat tatataaacc
     6601 gacggtctgt ttgattaaat aaaaaggaga gattttatgc aagcagaaaa aaaacttttt
     6661 aatcgtgatt ttatacttgt tgttatagga cagataattt ctttatttgg aaacgctatc
     6721 ctacgatttg cattaccgta ctatttgtta aaagaaactg gttcatcagc tttgtttggt
     6781 attgctacag cctgctcttt tttacctatg gttattttgt cgctggtagg tggtattatt
     6841 gctgacagga caaataaaag aaacattatg gtcatactag attttgtaac agcaatcata
     6901 attttagtat tttatttgtc attgggaaaa attcctatca tacctttgtt tattgttgct
     6961 ttgatgttac tttatggtat ttctggtgca tatcaaccag cggtacaagc aagtattcct
     7021 ctattggtat catcagataa acttaccgtc ggtaatgcta taataaatca agtaaatact
     7081 ttagcaaact ttatcggacc agctataagc ggagtagttt ttcaatttta tggtatcaat
     7141 cccattttaa ttgttagtat tatatgtttt actttttcag ccattatgga aatttttatc
     7201 catattccac accaaaaaag acctcgtgaa gtaggtgtaa ttgcagttgc taaaaacgat
     7261 ttaaaagata gttatacctt tttgaaaaag gagaaaccca tttttatatc cgtaatcttt
     7321 ttggtttgca ttttcaattt ggttttaagt gctgttttaa ttgttggtct gcctatctta
     7381 atttctgaag ttttaaaaat gccagataca ctatatggtt tttcacaatc agcattatca
     7441 ttaggtggtt tatgtggtgg tattttaaca gctcttgttg cttcaaagtt aaaactaaaa
     7501 aacctttata ccttgttact tatttgttct gtttctgttt tacttatggg aatttcgcta
     7561 tttttagaat tgcctgcaat agtttcctac tgggtagtta cagtgatgtg ctttgtggct
     7621 atgggtgtat ctactatgtt tgttgttcaa atttacactc ttgttcagac acaaacacca
     7681 ccgcaattag taggaaagat aatggctacg ctggtagcag ttgctatgtg cggtcaacct
     7741 attggacaaa tggtttacgg tattttattc gatgtattta tacaagaaac atgggttgtt
     7801 atgtttgtag cttctattgc ttcaatcatg atttcaatat attcaaaaag aatttttcaa
     7861 aagttagaga tataatacaa ggggttaaat agtatgttag gctaaaaaca atatataaaa
     7921 gaaaatttga aatctgctaa aaggatagtg ttataaaaga aagagtaata ttgcagtatt
     7981 taaggctcgc acaaatatat gttttgtgtg ggcttttttc ttaccatttt tctgtatttc
     8041 taaagggtat aaacggtatt ccgtttatat atttcagcat tagcagaaag ggggtgagat
     8101 tatgaggaca tcttctttcg agcatatcgt cagattacag ttcaattctt taatgctgat
     8161 tgtcattaag aacaaagtga aaagtcgaaa cagacagctt gcaagacatt ctaaacgtga
     8221 agtattgttt tgtgaaatag ccgaaacgaa acaagttgaa cgtggaacga ttgatacctg
     8281 tttttatgat tgtgtatcat ttaaagtctt gcactttaca atttatgtat ctgatgaaac
     8341 acttggtaca gttttacata gactgtcaga aaaacagcgt agtgcgattt tattacgtta
     8401 ttttcaagga atgaacgaca gagaaatttc agaactgtac catgtatcac gttctgctat
     8461 ttgcagtaga agaactagag gactaaggaa gttaaaaatg cttttgagcg aaaggaagta
     8521 aagaaatgag taaagattat ggctatccct cttttgaatt gatttgcaaa gcgtcaagcg
     8581 gagatgaaat ggcagttaaa gagattttga agttttatga cggttatatt tctaaattat
     8641 gcttgcgtcc tttttaccac tctgaaagtg gtaaaatcat tatgcaggtt gatgaagaac
     8701 taaaaggaga aattcataca gacatgatga aagcaatatt gaaatttgaa atcggagtga
     8761 agtaatcaac tgtataaaaa aatcgggaga tacacagttt cgtgctatct cccttagtag
     8821 ttttacggtc atatcaaggc tcattcaatc gtggtaaatt cgtggtaaga tgagtgtttt
     8881 tctatacttc aaaatgcttg aatgtatagt gtttatgcgg ataattgaaa attagatata
     8941 aaatttcaaa taaattactg atataaattt acaataagaa ctcttgtttc tacttttttt
     9001 tatgagaaaa tttagttttc aatttattga accattttcg gcttggatct cgacgttttt
     9061 tgatttgatg acccgtcacg tattcttgaa caactgcatt gatgattccg cccaaaatga
     9121 tgatcgtagc agcaaaatta agccaaagca tgagtacaat aaaacttcct atgatctgat
     9181 aaccgctgat cctcgttgca aaatacctag catagatact aaacacttgt gataacagca
     9241 tccagccgac agtagcgaag atcgtgcccg gaatgatcgt cttcaacttc aactgagcat
     9301 tagggacaat taaataaatc aagaacatga tgacaaataa agctaccaat gtgattggcc
     9361 acttcaaagt ttggaactga tcgataaagt tcacgggtat ttgtacgatt ggctgaatag
     9421 catccaaaat cagctgtccc aacccaagaa cgatagttac cccactaata gcaatcatga
     9481 acaagacaat gacaattagt gagaagaaac ggacgatcaa aaaatttttt ctattttcta
     9541 cgccatacgc tttattcatc gcaatttgca aagcattgat actttgactt gcagaccata
     9601 aagccgctaa tgcagaaacg gataacaagc ctcctgaact ttgtgtcaaa aggtctttga
     9661 ttgcaggacc gataaactgg taaacggtct caggaatcac ttctcgtaaa taggtcagta
     9721 cagtctcttg atcgatgtgg agaaacggta aaatattacc aaaagcaata atcaatggaa
     9781 ataaagacaa gagtaaataa taagcaacga cgacagaggt cgtactcatt tctgaatcag
     9841 tgatgcgctt ttgagtcgtc tcaataaagc gcatcagatt ttcattttgt tttattttgt
     9901 tccaaacttt catgtacctc tcccgtacct attgactgga tagatcaata agtgccttct
     9961 tctccttgtg atgtcaaaat tcttggacca tctttagtaa tagccaatgt atgttcatat
    10021 tggcaagaaa gtccgccgtc tcttgtatac gcagtccagc cgttaggatc cattttcatt
    10081 ttccaagttc cggtattaac cataggttcg atcgtgataa ccatgccttc tttcaaccgc
    10141 aacccttttc cagcttctcc gtaatgagga actgctggtt cttcatgaat cgtaggacca
    10201 acgccatgac caataaaatc acgaacgatc gctagatttt cgccttctac ataagtttgg
    10261 atagcatgac cgatgtcacc aatccgattc cctacttgtg cttgctcaat accgatgtac
    10321 aaagctttct tcgttacttc catcaatcgg tcgatctcag gtgtagattc tccaactaca
    10381 taggcccaac aagaatcaga aatgccgcct ttcaaatcga tacacatatc gacttttacc
    10441 aaatcaccgt ttttcaaagg ctttttacga gggaatccat gacaaatttc atcatttata
    10501 ctgatacaag tcgcatattc atacccttca aagccaattt gcgcagcaat tccgccatga
    10561 ctctcgatat agtttctgac aaatacctca atatcccaac ttgtgattcc tggttttata
    10621 aaatcacgca gatttttatg tacatctgct aataaagctc cagattctgc catcatttca
    10681 atttcacgtg ctgattttaa agtaatcata ttttcgtctc ctttttacaa atccctctca
    10741 ttttaacata gcggcataca tttagccaaa tgacattccc caggtgtctc taggttttat
    10801 tttcttttca atgatgtttt ggtataattc ataattgtta aataattata aacgaggagg
    10861 cacatcatgg ctttagcaaa aatcgtatat gctagcatga caggaaacac tgaagaaatc
    10921 gccgatattg ttgcagaagc atttgaaaat ctggatatcg aagtcgaaat caacgaatgt
    10981 acccaagtag atgcagatga attcgaggag gcagatattt gcgtagtagc tacttataca
    11041 tacgatgatg gcgatctgcc tgatgagatc gtagactttt atgaagactt gcaagaattg
    11101 gatctattgg gaaaaattta cggtgtctgc ggatctggtg atacttttta cgatgaattc
    11161 tgcaaatcgg tggatgattt cgatgctgct tttgcaaaaa caggcgcatc aaaaggagcc
    11221 gaaaatgtta aagtggatct gaatgctgaa gaagaagata tcgaaaattt agaagctttc
    11281 gctaaagaac tagtcgcaaa aatttaatat acttgcaata aaagagccat ccagatttat
    11341 tcaatctgta tggctctttt attcattgca ttcatggaag agttcttcgg gagttaaaaa
    11401 tgcatacgct gtaagaaaaa cgaacttttc cttattttga cacatctctt gttacctact
    11461 gatttgtgga acttttgagt atattcaatc gatttcgatt ggttctttga atttcaagat
    11521 agcatctata ctgtcttgga tcatcttttc aatctgttca tcagttggat ggatgatgct
    11581 tgaagacatc aaagctgcga tcccagtagc tatgatccat gtcccattat acaaagattc
    11641 gatctgctct tctgaaagat tcacataagc tggatcgcgt ttcactgtat tcacaaagta
    11701 agtataagag aaattctgca tctcttttcc tccaccatat tcttctaagt acagtgaacg
    11761 atacaacttc ttctctcttc ttgcaaaatg gatataatta aaagcaagat cgataatcgt
    11821 attccctgta tgctcaacag tgaacacttc atattgtaaa tgatcataga tctgctcaaa
    11881 aagagcttgt ctcaagtcat ccatattttt aaactcaaga taaatcggtt gcgtggaaca
    11941 attcattttg ttcgcgatgt ttctcgcagt aaatcgtgta aatccatcgg tggcagctac
    12001 ttcataagca gctgccaaaa tctgttctct agtaatcgtc ttttttcttg ccatattttt
    12061 taatctcctt aattttttta taacgcttcc accattgatt aatttcattg taacatgttt
    12121 tttttgatat gcaaaattag tttttgattt tcttcacaag ctgaaatagc aagtagtaac
    12181 atatatcatg aaacttaacc ttaaaaaaat aacctccttt ttttatttaa agcctcattg
    12241 tttgaatcat aattaaatgg tatcatgcta atagttacca gaaaaaatgg tgaggaggaa
    12301 tttttattat gttatctgat tttaatgaac ttctaaaaaa atatgcacgc ttaattgcag
    12361 aaactggcgt agccacagaa aaaggacaca cagttgtttt acagatcagc gtggaacagg
    12421 caccccttgc tcgattgatc acacaagaag cttataaact aggagccgct gaggttatcg
    12481 ttcaatggac tgacgaccag atccaaagag aatttctttt acatgctgca acggatcgta
    12541 ttgagaatgt accacaatct aaaatcgatc aagcggatga atggcttgaa aaaggagcaa
    12601 gcaggatcag cgttgtttct gccgatcccg atgcatttgc tggtgtagat agccatcgag
    12661 tagcgtctta tcaatcagcg aatggcaaag cactaatgaa tttacgcaag gcaactcaag
    12721 caaataaagt cagttggact gtcgtggctg cggctggtaa acaatgggca gcaaaagtct
    12781 tcccagaact gccagaagaa aaacaagttg aggcattatg ggatcagatt ttcaaaacga
    12841 ctcgtgtcta tgaagaagac cctgtcttag catggaagaa gcatgatgaa aaattagcaa
    12901 aaaaagcaga agaattgaat cgagaacaat tttctgccct tcactatact gctcccggta
    12961 cagatatcat tatcggattg cctaaaaacc atctttggga aggcgctgga agctataatg
    13021 ctcgtggaga aaaattcatg gcaaatatgc cgacggaaga agtgttcaca gcacctgaca
    13081 gtcatcgagt agatggttac atttcaagta caaagccact gagttatgct ggcaccatca
    13141 tctcgggtat gaaatttact tttaaagatg gaaaagttgt tgatttttct gccgaacaag
    13201 gagaagatgt cttagcaaaa ctgcttgata cagatgaagg tgcgcgtcgt ttaggagaag
    13261 tcgcacttgt acctgaccct tcacctattt ctcaatctgg catcatcttt ttcaatacat
    13321 tatttgatga aaacgcatcg aatcacttag cactaggttc tgcttatgcc ttcagtgtga
    13381 aaggcggtac agaaatgtcc gatgaagaat tagcagaagc tggattgaat agaagtcaaa
    13441 cccacgtaga tttcatggta ggatctgaca agatggatat cgacggaatc cgtgaagatg
    13501 gctctacagt accgattttc cgaaatggcg attgggcttg agtatacttt cgcacacatg
    13561 caaaaaataa tggctctttg tcaataagga ctgatgagtt gtgcaaaatc
//
LOCUS       DASHXG010000193        13213 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.068, whole genome shotgun sequence.
ACCESSION   DASHXG010000193 DASHXG010000000
VERSION     DASHXG010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.068"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(204..2162)
                     /locus_tag="U2R59_002956"
     CDS             complement(204..2162)
                     /locus_tag="U2R59_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEM8967261.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="U2R59_002957"
     CDS             complement(2159..3031)
                     /locus_tag="U2R59_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEM8967262.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="U2R59_002958"
     CDS             complement(3373..4245)
                     /locus_tag="U2R59_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEM8967263.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="U2R59_002959"
     CDS             4373..4942
                     /locus_tag="U2R59_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEM8967264.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="U2R59_002960"
     CDS             5009..5746
                     /locus_tag="U2R59_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEM8967265.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="U2R59_002961"
     CDS             5977..7245
                     /locus_tag="U2R59_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEM8967266.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="U2R59_002962"
     CDS             7732..8196
                     /locus_tag="U2R59_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEM8967267.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="U2R59_002963"
     CDS             8180..8809
                     /locus_tag="U2R59_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEM8967268.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="U2R59_002964"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="U2R59_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HEM8967269.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="U2R59_002965"
     CDS             10688..11134
                     /locus_tag="U2R59_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HEM8967270.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="U2R59_002966"
     CDS             complement(11333..11848)
                     /locus_tag="U2R59_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEM8967271.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="U2R59_002967"
     CDS             11965..13167
                     /locus_tag="U2R59_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEM8967272.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DASHXG010000194        11819 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.076, whole genome shotgun sequence.
ACCESSION   DASHXG010000194 DASHXG010000000
VERSION     DASHXG010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.076"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            39..977
                     /locus_tag="U2R59_002968"
                     /pseudo
     CDS             39..977
                     /locus_tag="U2R59_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            980..3163
                     /locus_tag="U2R59_002969"
     CDS             980..3163
                     /locus_tag="U2R59_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEM8967273.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            3160..4161
                     /locus_tag="U2R59_002970"
     CDS             3160..4161
                     /locus_tag="U2R59_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEM8967274.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            4176..5090
                     /locus_tag="U2R59_002971"
     CDS             4176..5090
                     /locus_tag="U2R59_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEM8967275.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5335..5451
                     /locus_tag="U2R59_002972"
     CDS             5335..5451
                     /locus_tag="U2R59_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEM8967276.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            5467..7386
                     /gene="tet(M)"
                     /locus_tag="U2R59_002973"
     CDS             5467..7386
                     /gene="tet(M)"
                     /locus_tag="U2R59_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEM8967277.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQREVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            7484..8857
                     /gene="tet(L)"
                     /locus_tag="U2R59_002974"
     CDS             7484..8857
                     /gene="tet(L)"
                     /locus_tag="U2R59_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HEM8967278.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            9421..10683
                     /locus_tag="U2R59_002975"
     CDS             9421..10683
                     /locus_tag="U2R59_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HEM8967279.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            10928..11815
                     /locus_tag="U2R59_002976"
     CDS             10928..11815
                     /locus_tag="U2R59_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HEM8967280.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKKWFCCKVLNKE"
BASE COUNT         3932 a         1956 c         2463 g         3468 t
ORIGIN      
        1 acttggagat aacatcaaaa agttacctat cgctataacg tggcagatgg aaagaaacct
       61 tgccagagat ttcccatgaa atcaatatcg tcaatctgac ttctgatgag aaaaacaaag
      121 gcttacttga cccttatgta attatgaaaa ataccaaaga ttctgaatca ctggctattg
      181 atattttgac attccttacg gggatttcct ctcgtgatgg ggaacgcttc ccaatcctta
      241 gaaaagccat tcgtgcagta accaatagtg aagtgcgagg gttgatgaaa gtgattgaag
      301 aattacgggt tgagaatacg ccactaagta ccagcatagc cgaccatatc gaaagtttta
      361 cagactatga ctttgcccat ctgcttttta gtgatggtta tgtagagcag tctatcagcc
      421 ttgaaaaaca actgaacatt atacaggttg ccgacttggt acttcctgac aaggaaactt
      481 cctttgagga atataccaca atggagttac tatcggtagc aatgctgatt gtcattagta
      541 cctttgcgtt ggactttatc catacagacc gaagtatttt caagattgta gacttagacg
      601 aagcatggag cttcttacag gtggcacaag ggaaaacact atctatgaag ctggttcgtg
      661 ctggtcgtgc tatgaacgct ggggtatatt tcgtgaccca aaatacagat gacctcttag
      721 atgaaaaact gaaaaataac ctcggcttaa aatttgcctt tcgttccact gaccttaacg
      781 agattaaaaa aacccttgcc ttttttggtg tagacccaga ggacgaaaac aatcagaagc
      841 gattgcgtga tttggaaaac gggcaatgcc ttatcagtga tttatatggt cgtgtcggtg
      901 tgatacagtt ccaccctgta tttgaagaac tgctccatgc ctttgatacc agaccacctg
      961 tgcgaaaaga ggtgtaaatg tgaaaccatc aatattaaac agaataaaat caaactggac
     1021 gctgaaacgt ctaggtaaag tggcaatgac agtggctttc acacttgtga ttgccatttt
     1081 tcttttagcc atgctgggaa cggtggttca agctgcgggc ttggtagatg atacggtcaa
     1141 tgtggcaaat gaatacagcc gatacccact tgaaaactat caactggatt tttatgtgga
     1201 taatagctgg ggctggctac cgtggaactg gtcggacgga attggaaaac aagtcatgta
     1261 tggactatat gccattacca attttatttg gacaatcagt ctttatgttt ccaatgcgac
     1321 gggttactta gtacaggaag cctattcctt agacttcatt tccgctacag cagattccat
     1381 tggcaagaat atgcagaccc ttgcaggggt tacgcctagt ggactatcaa cagagggttt
     1441 ctatgttgga ttccttttac tcttgatttt ggttcttggg gtttatgttg cctatacagg
     1501 actgataaag agagaaacca caaaggcaat tcatgccctc atgaattttg tgctggtttt
     1561 tatcctatcg gcttccttta ttgcctacgc tcccgactac attaaaaaaa tcaatgactt
     1621 ttcatcagac atcagcaacg ctagtttgtc actgggtaca aaaattgtca tgccccattc
     1681 agatagtcaa ggcaaggaca gtgtggactt gatacgtgac agcctatttt ccatacaggt
     1741 tcagcaaccg tggctactgc ttcaatataa cagttcagac attgaaagta ttggtattga
     1801 ccgtgtggaa agcctgctct caaccagtcc agattccaac aatggggaag acagagaaaa
     1861 aattgttgcg gaagaaattg aagatagaag caataccaat atgacgatta caaagacgat
     1921 taaccgttta ggtacagtct tcttcctatt tgtcttcaat attgggattt ccatatttgt
     1981 attcctatta acaggaatca tgattttctc gcaggtactt tttatcatct atgctatgtt
     2041 tctgcctgtg agctttattt taagcatgat tccatcattt gatggtatgt caaaacgagc
     2101 cataacaaag ctctttaata ccattttgac acgagctgga atcacattga ttattacgac
     2161 agcatttagt atttcaacca tgctctatac cttatcggct ggttatccgt tctttttgat
     2221 tgcttttcta cagattgtga cctttgcagg aatctacttt aagctgggcg atttaatgag
     2281 tatgttttct ctacagagta acgattctca aagtgtggga agtcgtatga tgagaaaacc
     2341 tcgtatgctt atgcacgctc acatgcaccg tctacagcgg aaacttggac gctccgtgac
     2401 tgctttaggg gctgggtctg ccattgccag tgctacgggt aaaaaaggac agtcgggttc
     2461 gggaagttct gcgagtacac aagcagatca ctctcgacca aacgggcagg aaaaatcaac
     2521 actaggaaag cgtatcggtc aaaccatcgg tacagtagct gataccaaag acagaatggt
     2581 agatactgct ggtaatttga aagaacaggt taaggatttg ccgaccaatg caagatatgc
     2641 agtatatcaa ggaaaatcta aagtgacgga taatgtccat gatttaacca gaagtatttc
     2701 tcaaaccaaa gcggataaag ccagtggacg caagaaacag caggaacaaa gacggaaaac
     2761 cattgcggag cgtcgctctg aaatggaaca ggtcaaacag aaaaaacagc cagcttcttc
     2821 cgttcatgaa agaccagcca ctaagcaaga acaatctcat gatggacaga cttcaaggca
     2881 aacaactgta caggcttcct atagggaatc tcaacaagcc aaacaagagc gtccaacagt
     2941 taagtccgat tcttcaagtt taaaaacgga acgtcaaagt aatacagttc aagaaagaac
     3001 ggttcaaaag ccagtaactt caactgcacc aacagataga gcttcacaac gttcaatcac
     3061 aaaagaacgt cagtctactg ttcaaagagt accactacaa aatacaaaaa gtagaccacc
     3121 aatcaaaacc gccaccatta agaaaggcag taagaaacca tgaagctgaa aactttagtg
     3181 attggtggtt cgggattatt cttgatggtc ttctcactgc ttctgtttgt cgccatttta
     3241 ttttcagatg aacaagatgg cggtttttcc aacattcact atggcggtgt ggatgtttcc
     3301 gcagaagtgc tggctcataa gcctatggta gaaaaagttg ccaaagaata tggaattgaa
     3361 gaatacgtca atatacttct tgcgattata caggtggaat cgggtggtac agcagaagat
     3421 gttatgcagt cctcggaatc cctcggtctt ccacctaatt cattgagtac agaagaatcc
     3481 attaagcaag gtgtgaagta tttcagtgag ttattagcca gtagcgaaag gcttggtgta
     3541 gatttagaat cggttatcca gtcctacaat tatggtggtg gtttcttagg atatgtggct
     3601 aatcgtggga ataaatatac ctttgaactg gctcaaagtt tctcaaaaga gtattcgggt
     3661 gacgaaaaag tgtcttaccc caatcccata gccataccta tcaatggggg ctggcgatac
     3721 aattacggga atatgtttta tgtgcaactg gtaacgcagt atcttgtcac aacagagttt
     3781 gatgatgata cagtacaagc catcatggac gaagctctga aatttgaagg ctggaagtat
     3841 gtctatggcg gagcttcccc gactacctct tttgattgta gcggactgac acaatggacg
     3901 tatggaaaag ctggaatcaa cttaccacga acagcacaac agcaatatga tgtaacccgg
     3961 catatcccat tattggaagc aaaagccggc gatttggttt tctttcattc tacctataac
     4021 gctggctctt atattactca tatcgggatt tatttaggcg ataaccgtat gtttcatgca
     4081 ggcgacccta tcggttatgc cgacttaaca agctcttact ggcaacagca tttagtggga
     4141 gcaggacgaa tcaaacaata agaaaggacg attcaatgat gaaattcgga aaaaatcaga
     4201 atacagaaaa acagacacca aaggaaaaga aacctcgtgt ctataaggtc aatcctcgta
     4261 aaaaggttgt gattgtccta tgggtacttt taggacttag tttcagcttt gcgatattca
     4321 agcactttac agccattgat acccatacca ttcatgaaac caccatcata gaaaaggaat
     4381 atgtcgatac tcatcatgtg gaaaattttg tagagaactt tgcgaaagtc tactattcat
     4441 gggaactaaa cgacaagtcc attgataatc gcatagaaaa cctgaaagca tatctgacag
     4501 aggaacttca agctctgaat gtcgatacag ttcgtaaaga tattcctgta tcgtcttctg
     4561 taaaaggatt tcagatatgg acggtagaag cagatggcga caatcaattt gatgtaacct
     4621 acagtgtaga ccaactcatt acagaggggg aaaatacaaa gaccgtccac tctgcttata
     4681 tagtgagtgt ctatgtagac agtactggaa atatggtcct cattaagaat ccgaccatta
     4741 ctagcatacc aaagaaatca gactataaac caaaagctat tgaaagtgag ggtacggttg
     4801 attccattac aaccaatgaa atcaatgagt ttttaacgac gttcttcaag ctctatccta
     4861 cagcgacagc cagtgaactt tcctactatg tgaatgacgg gatattaaaa ccaatcggaa
     4921 aagagtacat ctttcaagaa ctggtaaatc ctatttacaa tcgtaaggat aatcaagtca
     4981 cggtatcgct gacagtggag tatatcgacc agcagaccaa agcaacgcag gtatctcaat
     5041 ttgatttggt acttgaaaag aacgggagta attggaagat tatagaataa caaatattgg
     5101 tacattatta cagctatttt gtaatcacgt actctctttg ataaaaaatt ggagattcct
     5161 ttacaaatat gctcttacgt gctattattt aagtatctat ttaaaaggag ttaataaata
     5221 tgcggcaagg tattcttaaa taaactgtca atttgatagt gggaacaaat aattggatgt
     5281 ccttttttag gagggcttag ttttttgcac ccagtttaag aataccttta tcatgtgatt
     5341 ctaaagtatc cggagaatat ctgtatgctt tgtatgccta tggttatgca taaaaatccc
     5401 agtgataaga gtatttatca ctgggatttt tatgcccttt tgggcttttg aatggaggaa
     5461 aatcacatga aaattattaa tattggagtt ttagctcatg ttgatgcggg aaaaactacc
     5521 ttaacagaaa gcttattata taacagtgga gcgattacag aattaggaag cgtggacaaa
     5581 ggtacaacga ggacggataa tacgctttta gaacgtcaga gaggaattac aattcagaca
     5641 ggaataacct cttttcagtg ggaaaatacg aaggtgaaca tcatagacac gccaggacat
     5701 atggatttct tagcagaagt atatcgttca ttatcagttt tagatggggc aattctactg
     5761 atttctgcaa aagatggcgt acaagcacaa actcgtatat tatttcatgc acttaggaaa
     5821 atggggattc ccacaatctt ttttatcaat aagattgacc aaaatggaat tgatttatca
     5881 acggtttatc aggatattaa agagaaactt tctgccgaaa ttgtaatcaa acagaaggta
     5941 gaactgtatc ctaatatgtg tgtgacgaac tttaccgaat ctgaacaatg ggatacggta
     6001 atagagggaa acgatgacct tttagagaaa tatatgtccg gtaaatcatt agaagcattg
     6061 gaactcgaac aagaggaaag cataagattt cagaattgct ccttgtaccc tgtttatcat
     6121 ggaagcgcaa aaagcaacat agggattgag cagcttatag aagtgataac gaataaattt
     6181 tattcatcaa catacagaaa gaagtctgaa ctttgcggaa atgtcttcaa aattgaatat
     6241 tcggaagaaa gacaacgtct tgcatatgta cgcctttatg gcggaatcct gcatttgcgg
     6301 gattcggtta gaatatcgga aaaggaaaaa ataaaaatta cagaaatgta tacttcaata
     6361 aatggtgaat tatgtaaaat tgataaggct tattccgggg aaattgttat tttgcaaaat
     6421 gagtttttga agctaaatag tgttcttgga gatacaaagc tattgccaca gagagagaga
     6481 attgaaaatc cgctccctct gctgcaaaca actgttgaac cgagcaaacc tcaacaaagg
     6541 gaaatgttac ttgatgcact tttagaaatc tccgacagtg acccgcttct acaatattat
     6601 gtggattcta cgacacatga aattatactt tctttcttag ggaaagtaca aagggaagtg
     6661 attagtgcac tgttgcaaga aaagtatcat gtggagatag aactaaaaga gcctacagtc
     6721 atttatatgg agagaccgtt aaaaaatgca gaatatacca ttcacatcga agtgccgcca
     6781 aatcctttct gggcttccat tggtttatct gtatcaccgc ttccgttggg aagtggaatg
     6841 cagtatgaga gctcggtttc tcttggatac ttaaatcaat catttcaaaa tgcagttatg
     6901 gaagggatac gctatggttg cgaacaagga ttatatggtt ggaatgtgac ggattgtaaa
     6961 atctgtttta agtatggctt atactatagc cctgttagta ccccagcaga ttttcggatg
     7021 cttgctccta ttgtattgga acaagtctta aaaaaagctg gaacagaatt gttagagcca
     7081 tatcttagtt ttaaaattta tgcgccacag gaatatcttt cacgagcata caacgatgct
     7141 cctaaatatt gtgcgaacat cgtagacact caattgaaaa ataatgaggt cattcttagt
     7201 ggagaaatcc ctgctcggtg tattcaagaa tatcgtagtg atttaacttt ctttacaaat
     7261 ggacgtagtg tttgtttaac agagttaaaa gggtaccatg ttactaccgg tgaacctgtt
     7321 tgccagcccc gtcgtccaaa tagtcggata gataaagtac gatatatgtt caataaaata
     7381 acttagtgta ttttatgttg ttatataaat atggtttctt gttaaataag atgaaatatt
     7441 ttttaataaa gatttgaatt aaagtgtaaa ggaggaatta attatgaagt gtaatgaatg
     7501 taacagggtt aaatacaacc aaattttaat ttggctttgc gttttatctt tttttagcgt
     7561 attaaatgaa atggttttga acgtctcatt acctgatatt gcaaatgatt ttaataaacc
     7621 acctgcgagt acaaactggg tgaacacagc ctttatgtta accttttcca ttggaacagc
     7681 tgtatatgga aagctatctg atcaattagg catcaaaagg ttactcctat ttggaattat
     7741 aataaattgt ttcgggtcgg taattgggtt tgttggccat tctttctttt ccttacttat
     7801 tatggctcgt tttattcaag gggctggtgc agctgcattt ccagcactcg taatggttgt
     7861 agttgcgcgc tatattccaa aggaaaatag gggtaaagca tttggtctta ttggatcgat
     7921 agtagccatg ggagaaggag tcggtccagc gattggtgga atgatagccc attatattca
     7981 ttggtcctat cttctactca ttcctatgat aacaattatc actgttccgt ttcttatgaa
     8041 attattaaag aaagaagtaa ggataaaagg tcattttgat atcaaaggaa ttatactaat
     8101 gtctgtaggc attgtatttt ttatgttgtt tacaacatca tatagcattt cttttcttat
     8161 cgttagcgtg ctgtcattcc tgatatttgt aaaacatatc aggaaagtaa cagatccttt
     8221 tgttgatccc ggattaggga aaaatatacc ttttatgatt ggagttcttt gtgggggaat
     8281 tatatttgga acagtagcag ggtttgtctc tatggttcct tatatgatga aagatgttca
     8341 ccagctaagt actgccgaaa tcggaagtgt aattattttc cctggaacaa tgagtgtcat
     8401 tattttcggc tacattggtg ggatacttgt tgatagaaga ggtcctttat acgtgttaaa
     8461 catcggagtt acatttcttt ctgttagctt tttaactgct tcctttcttt tagaaacaac
     8521 atcatggttc atgacaatta taatcgtatt tgttttaggt gggctttcgt tcaccaaaac
     8581 agttatatca acaattgttt caagtagctt gaaacagcag gaagctggtg ctggaatgag
     8641 tttgcttaac tttaccagct ttttatcaga gggaacaggt attgcaattg taggtggttt
     8701 attatccata cccttacttg atcaaaggtt gttacctatg gaagttgatc agtcaactta
     8761 tctgtatagt aatttgttat tacttttttc aggaatcatt gtcattagtt ggctggttac
     8821 cttgaatgta tataaacatt ctcaaaggga tttctaaatc gttaagggat caactttggg
     8881 agagagttca aaattgatcc tttttttata acaggaattc aaatcttttt gttccattaa
     8941 agggcgcgat tgctgaataa aagatacgag agacctctct tgtatctttt ttattttgag
     9001 tggttttgtc cgttacacta gaaaaccgaa agacaataaa aattttattc ttgctgagtc
     9061 tggctttcgg taagctagac aaaacggaca aaataaaaat tggcaagggt ttaaaggtgg
     9121 agattttttg agtgatcttc tcaaaaaata ctacctgtcc cttgctgatt tttaaacgag
     9181 cacgagagca aaacccccct ttgctgaggt ggcagagggc aggttttttt gtttcttttt
     9241 tctcgtaaaa aaaagaaagg tcttaaaggt tttatggttt tggtcggcac tgccgacagc
     9301 ctcgcagagc acacacttta tgaatataaa gtatagtgtg ttatacttta cttggaagtg
     9361 gttgccggaa agagcgaaaa tgcctcacat ttgtgccacc taaaaaggag cgatttacat
     9421 atgagttatg cagtttgtag aatgcaaaaa gtgaaatcag ctggactaaa aggcatgcaa
     9481 tttcataatc aaagagagcg aaaaagtaga acgaatgatg atattgacca tgagcgaaca
     9541 cgtgaaaatt atgatttgaa aaatgataaa aatattgatt acaacgaacg tgtcaaagaa
     9601 attattgaat cacaaaaaac aggtacaaga aaaacgagga aagatgctgt tcttgtaaat
     9661 gagttgctag taacatctga ccgagatttt tttgagcaac tggatccagg agaacaaaaa
     9721 cgattttttg aggaaagtta taaattattt tccgaacgat atggcaagca aaatattgct
     9781 tatgcaacag ttcataatga tgagcaaacc cctcacatgc atttaggtgt tgtgcctatg
     9841 cgtgatggaa aactgcaagg aaaaaatgtg tttaatcgtc aagaactgtt atggctacaa
     9901 gataaattcc ccgagcatat gaaaaaacag ggttttgagt tgaagcgtgg tgaacgtggc
     9961 tctgaccgta aacatattga gacagctaaa tttaaaaaac aaactttgga aaaagagatt
    10021 gattttctag aaaaaaattt agcagttaaa aaagatgaat ggactgctta tagcgataaa
    10081 gttaaatcag atttagaagt accagcgaaa cgacacatga aaagtgttga agtgccaacg
    10141 ggtgaaaagt ccatgtttgg tttgggaaaa gaaataatga aaacagaaaa gaaaccaacc
    10201 aaaaatgttg ttatatcgga gcgtgattat aaaaacttag tgactgctgc gagagataac
    10261 gataggttaa aacagcatgt tagaaatctc atgagtactg atatggcgag agaatataaa
    10321 aaattaagta aagaacatgg gcaagttaaa gaaaaatata gtggtcttgt agagcgattt
    10381 aatgaaaatg taaatgatta taatgagttg cttgaagaaa acaagtcttt aaagtctaaa
    10441 ataagcgatt taaagcgtga tgtgagttta atctatgaaa gcactaagga attccttaag
    10501 gaacgtacag acggcttaaa agcctttaaa aacgttttta aggggtttgt agacaaggta
    10561 aaggataaaa cagcacaatt ccaagaaaaa cacgatttag aacctaaaaa gaacgaattt
    10621 gaactaactc ataaccgaga ggtaaaaaaa gaacgaagtc gagatcaggg aatgagttta
    10681 taaaataaaa aaagcacctg aaaaggtgtc tttttttgat ggttttgaac ttgttctttc
    10741 ttatcttgat atatatagaa ataacgtcat ttttatttta gttgctgaaa ggtgcgttga
    10801 agtgttggta tgtatgtgtt ttaaagtatt gaaaaccctt aaaattggtt gcacagaaaa
    10861 accccatctg ttaaagttat aagtgaccaa acaaataact aaatagatgg gggtttcttt
    10921 taatattatg tgtcctaata gtagcattta ttcagatgaa aaatcaaggg ttttagtgga
    10981 caagacaaaa agtggaaaag tgagaccatg gagagaaaag aaaatcgcta atgttgatta
    11041 ctttgaactt ctgcatattc ttgaatttaa aaaggctgaa agagtaaaag attgtgctga
    11101 aatattagag tataaacaaa atcgtgaaac aggcgaaaga aagttgtatc gagtgtggtt
    11161 ttgtaaatcc aggctttgtc caatgtgcaa ctggaggaga gcaatgaaac atggcattca
    11221 gtcacaaaag gttgttgctg aagttattaa acaaaagcca acagttcgtt ggttgtttct
    11281 cacattaaca gttaaaaatg tttatgatgg cgaagaatta aataagagtt tgtcagatat
    11341 ggctcaaaga tttcgccgaa tgatgcaata taaaaaaatt aataaaaatc ttgttggttt
    11401 tatgcgtgca acggaagtga caataaataa taaagataat tcttataatc agcacatgca
    11461 tgtattggta tgtgtggaac caacttattt taagaataca gaaaactacg tgaatcaaaa
    11521 acaatggatt caattttgga aaaaggcaat gaaattagac tatgatccaa atgtaaaagt
    11581 tcaaatgatt cgaccgaaaa ataaatataa atcggatata caatcggcaa ttgacgaaac
    11641 tgcaaaatat cctgtaaagg atacggattt tatgaccgat gatgaagaaa agaatttgaa
    11701 acgtttgtct gatttggagg aaggtttaca ccgtaaaagg ttaatctcct atggtggttt
    11761 gttaaaagaa atacataaaa aatggttctg ttgcaaagtt ttaaataaag aataaaatc
//
LOCUS       DASHXG010000195         7958 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.092, whole genome shotgun sequence.
ACCESSION   DASHXG010000195 DASHXG010000000
VERSION     DASHXG010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.092"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            128..1564
                     /locus_tag="U2R59_002977"
                     /pseudo
     CDS             128..1564
                     /locus_tag="U2R59_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            1753..4200
                     /locus_tag="U2R59_002978"
     CDS             1753..4200
                     /locus_tag="U2R59_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEM8967281.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="U2R59_002979"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="U2R59_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEM8967282.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="U2R59_002980"
     CDS             complement(5690..6793)
                     /locus_tag="U2R59_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEM8967283.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="U2R59_002981"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="U2R59_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HEM8967284.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1358 c         1729 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatta agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DASHXG010000196         7848 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.093, whole genome shotgun sequence.
ACCESSION   DASHXG010000196 DASHXG010000000
VERSION     DASHXG010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.093"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            352..522
                     /locus_tag="U2R59_002982"
     CDS             352..522
                     /locus_tag="U2R59_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967285.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            536..1138
                     /locus_tag="U2R59_002983"
     CDS             536..1138
                     /locus_tag="U2R59_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967286.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1154..1831
                     /locus_tag="U2R59_002984"
                     /pseudo
     CDS             1154..1831
                     /locus_tag="U2R59_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2142..2306
                     /locus_tag="U2R59_002985"
                     /pseudo
     CDS             2142..2306
                     /locus_tag="U2R59_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
     gene            2343..2639
                     /locus_tag="U2R59_002986"
     CDS             2343..2639
                     /locus_tag="U2R59_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HEM8967287.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2640..3056
                     /locus_tag="U2R59_002987"
     CDS             2640..3056
                     /locus_tag="U2R59_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEM8967288.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3076..4620
                     /locus_tag="U2R59_002988"
     CDS             3076..4620
                     /locus_tag="U2R59_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967289.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4763..4987
                     /locus_tag="U2R59_002989"
     CDS             4763..4987
                     /locus_tag="U2R59_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967290.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5002..5871
                     /locus_tag="U2R59_002990"
     CDS             5002..5871
                     /locus_tag="U2R59_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEM8967291.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5852..6586
                     /locus_tag="U2R59_002991"
     CDS             5852..6586
                     /locus_tag="U2R59_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8967292.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6619..7527
                     /locus_tag="U2R59_002992"
     CDS             6619..7527
                     /locus_tag="U2R59_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HEM8967293.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7524..>7848
                     /locus_tag="U2R59_002993"
     CDS             7524..>7848
                     /locus_tag="U2R59_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967294.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDF"
BASE COUNT         2796 a         1209 c         1699 g         2144 t
ORIGIN      
        1 caagaagcat tttattctag cttaatttga caaatcatac tatgatacgt gtttgttttt
       61 ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt aagattttaa ttaattatta
      121 gggggagaag gagagagtag cccgaaaact tttagttggc ttggactgaa cgaagtgagg
      181 gaaaggctac taaaacgtcg aggggcagtg agagcgaagc gaacacttga tcttttaagt
      241 tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc taatatggtt ttagcagtat
      301 aattgacttg gtgaataggt catttaagtt gggcataata ggaggagtaa aatgaaaaaa
      361 tttatttatc gagttttaga aaatgacgaa gtggtggcta tttttaatga gcaacaatat
      421 gcgcaagatt ttatcgctta cgaaaagaca atttctgata agcaatttga aattgaaaaa
      481 gtagatatag ctgattggtt attgcaaccg agagaatttt agaggttggt tgaaaatggc
      541 taaaattggt tatgcacgtg tcagtagcaa agaacagaac ttagatagac aactgaaagc
      601 gttagagggc gtttctaagg tcttttcaga caaattaagc ggtcaatcgg tcgaacgccc
      661 acaattacaa gctatgctta actatattcg tgaaggggat atagttgttg ttactgaatt
      721 agatcgatta ggacgaaata ataaagaatt aacagaattg atgaatcaaa ttcaaattaa
      781 gggggcaacc ctggaagtct taaatttacc ctcaatgaat ggtattgaag atgaaaattt
      841 aagacggctg attaataatt tagtgattga attgtataag taccaagcgg aatctgaacg
      901 caaacgaatt aaagaacgcc aagcccaagg aattgaaatt gctaagaaaa aaggaaaatt
      961 caaagggcga caacctaaat tcaaagaaaa tgatccacgt ttacaacacg ctttcgattt
     1021 atttttgaat ggttgttccg ataaagaagt tgaagaacaa actggaatta atcgccgaac
     1081 gtttagaagg tatcgatcaa gatacaacgt gacagtagat caaagaaaaa aacaatgaaa
     1141 agagggatag ttaatgagta cggttatttt agctgaaaaa ccaagccagg cattagccta
     1201 cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat tttgagatca aagacccact
     1261 atttacagat gaaacgttta tcacctttgg ttttgggcat ttagtcgaat tagcagaacc
     1321 aggtcattat aacgaaaagt ggcagaactg gaaacttgaa tctttgccga tttttcctga
     1381 tcgatacgat tttgaagttg caaaagataa gggaaagcag tttaaaattg ttgctgaact
     1441 tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc gacagagaag gtgaaaatat
     1501 cgcctggtcg attatccata aagcaaatgc cttttctaaa gataaaacgt ataaaagatt
     1561 atggatcaat agcttagaaa aagatgtgat ccgaagcggt tttcaaaatt tgcaaccagg
     1621 aatgaattac tatccctttt atcaagaagc gcaaacacgc caaattgccg attggttgat
     1681 cggcatgaac gcaagccctt tatatacctt gaatttacaa caaaaaggcg tacaaggtac
     1741 attttcatta ggacgtgtac aaacaccgac tttatatctc atttatcaac gccaggaagc
     1801 aatagaaaac tttaaaaaag aacctttttt cctgaataat tcatagtttt actaatagtc
     1861 tttcctaaca ttgatttaat agtctttaaa gtattctgct tcatcaccca ttaggtgatg
     1921 aaaaaagaac ccctttctga tttagcggac aaatactttg acctaatctc agaagatata
     1981 aaagaaaaaa taataaaata tccgatttat actttgtata aagaactaaa gtagttagca
     2041 aatcatttac agcaaatcac tatgttccac ataccatttt acatacttac cttatccacg
     2101 acacatgttg agatagtatc gaagataaag aaagttgctc catgttgttt ttgcgagatg
     2161 gggaaatcaa agccacattg acaaccatga tgaataagct tgctttcagt cataagctaa
     2221 tcctagaacc acttttcaag tcagttagcc aaatcgatga agaaagcgac cgtgaaagaa
     2281 tggacgctat tgataagcta atggagcaac tattggaaga acgcaatacc cttattgcac
     2341 tgatgtccaa aggtttccta gaacctgctc tttttaatca ggaacgaaat gttttagata
     2401 gtgagattaa aaatcttact accgaaaaaa caaacctggt aacgaactct gcgagtgggg
     2461 ttttgcgagc aaacgagata aaggacctca ttaattatgt gtcagcagat aattttaatg
     2521 gtgactacac ggaagaacta tttgaagaat ttgtagtgaa catcattgta aattccaggg
     2581 atgagctgac attcaatttg aaatgcggtc tttccctgaa agaaaaggtg gtgagataaa
     2641 tggcatatat tccatatgga tacaaaattc aagatggagt ggttactgtc gatgaaaagg
     2701 cagcaggtca agtaaaggta ttctttgaga aatacatatc aggactatcc cttacagtgg
     2761 ctggcgaaca ggcaggtatt gaaaagacac attctgtgat ggggcgcatt ttgaaaaacg
     2821 tcaactacct tggaaatgat acgtatccag caattattga taaagagata tttgataaag
     2881 ctgaagaagt tagagataaa cgtgcaaagg atttaggacg agtggtagag cttgccgctt
     2941 tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa ggcagataat aagatgccag
     3001 tggatccttt tgaacgagca gaatacttat acagtctgat agaaagcgag gaataaagtg
     3061 acagagaaaa atataatggt tattcctgct cgtaaaagag taggaagtac agccgcaaaa
     3121 gaaaagataa agaaacttcg tgttgctgcc tattgccgtg tttctacaga aacagaagaa
     3181 caaaattcta gctatgaggt tcaggtctca cactatacag agtttataaa gaaaaataat
     3241 gaatgggagt ttgctggcat ctttgcagat gatggtatct ctggtacgaa cactaaaaag
     3301 cgtgacgaat ttaatcgcat gattgcagag tgtatggacg gtaacatcga catggttatt
     3361 acaaaatcca tcagccgatt tgcgcgtaac accctagact gccttcaata cattagacag
     3421 ctcaaggata agaacatatc agtttatttt gagaaagaga acatcaacac cacggatgcc
     3481 aaaggtgagg ttttgctgac tattatggca tctttggcac agcaggaaag ccagagcctt
     3541 tcacaaaacg ttaagcttgg gctacagtac cgataccaac aaggaaaggt gcaggtcaac
     3601 cataagcgat ttatgggcta cacgaaagat gaagatggaa atttaactat tgtccccgaa
     3661 gaagctgaga ttatcaaacg catctaccga gaataccttg agggtcagag tctagtgggc
     3721 attggtcgag cccttgaaaa ggatggtatt ttaacagcag cgggaaaacc aagatggcga
     3781 ccagaatcag ttaagaagat acttcaaaac gaaaaataca tcggagatgc ccttctgcaa
     3841 aagactgtca cagtagattt tctgaccaag aaacgagtga aaaatgaagg gcatgttccc
     3901 caatattatg ttgaaaatag ccatgaagcg attattccta aagagttatt tttgcaggcg
     3961 caagaagaaa ttcatcggag aagcaatatc tacacaggag aaggcaagaa caaaagaatt
     4021 tacagtagca agtacgcttt aagtgccatc accttctgtg gagattgtgg cgatatttat
     4081 agacgggtct attggaatat ccacggaaga aaagaatttg tctggcgatg cgtgactaga
     4141 atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa aagaagatga actttatggt
     4201 gcagtaatga ctgcgattaa taagctactt gcaggtggga acaatatgat aaagacactg
     4261 gaagagaata ttcatgctgt gattggcgaa accacagaat accaaatttc agagattaac
     4321 aactcactag aggaaaaaca aaaagaacta atcaagctgg cgaacaaggg tcaagactat
     4381 gaccacttag cagatgagat tgatgagctg agagacaagc gacagatcct tttagtagaa
     4441 gatgcctccc tcagtggcga gaacgagcga atcaatgagc tgattgaatt tatccgcaag
     4501 aacaaattcc gcaccttaga atatgatgat aagcttgtaa ggaagataat ccagagcgtt
     4561 acagtctatg aaggccactt cgtcatagcc ttcaaatctg gcatcgaaat ggaaatatga
     4621 aaaccagaag taaatagccc atgactctac agtagagttg tgggttttct tttgcttgct
     4681 gattataata atattttaat aactattgtg tttatcaacc aaatggttta taatattctt
     4741 agcgtaaact tggaggtgct gtatgactac ggcagaaatg attaaagaac tgtgtgagca
     4801 aatgaatata agtgtttccg aacttgctag acgtattggc cagactccac agaatttcaa
     4861 taaaaaatta caacgagaaa cagtaacctt ggatgagttg aaggccattg ctgatgtgct
     4921 aggtgtcaag tttgtgcagg catttatttt accagatgga gaagaaataa aaatatctaa
     4981 cgaataaagg aggatgttta tatggtaggt aatgttattc aaatagtaac agagaaatta
     5041 tcatctttgc cttttataga aggcatcgta ttagggggct cacgtgcaag aggcacccat
     5101 acagaaaatt ctgatataga tatcggaatc tattacaatt cagactcatt tgacctgaca
     5161 gcgattaatc aaattgctac agagttggat gatgagaata gaaacaacct tgttgtacct
     5221 cccggagcgt ggggtgattg ggttaatggc ggtggatggt tagttataaa cgggtgtcat
     5281 gttgacttga tattacgtga tataaaacgg gtggaacaaa taatcaaaga tacggagcaa
     5341 ggaattgtta ctgccaatta tcagaccggg catccccatg gttatataag tgctatgtat
     5401 cgtggagaat tagcgattag taaaatacta tatgctaaga acgaaagctt atgcgaatta
     5461 aaaaagcagg cagaaattta ccctactgct ctaaagaaaa gcttgatgaa cttttttata
     5521 tttgaagctg aattctcttt aatgtttgta aaagcaaatg cgggggcaga ggataaatat
     5581 tatattgcag gccatgtttt tcgtattatt tcatgcttaa atcaagtact atttgcatgt
     5641 aataatgctt attgcattaa cgaaaagaaa gctataaaac tgcttgaaac ttttgaatat
     5701 aaacctgaaa aatatgccga aagagttaat catatttttg aagtactcgg tctttctctt
     5761 tttgaatgct acgacatgac cgagaaactt tataaagaag tgaatgaaat tgtatcggag
     5821 ataaataact ttttaaacga ggagagttca gatgaaagaa aacaaatatg atgataatat
     5881 attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa ggactggctg gtgcgggaga
     5941 atgggagact ttgaaaaaga tgctacctga ttttaagggt aagcgtgtgc ttgatttagg
     6001 atgcggctat ggatggcact gtatatatgc gatggaaaac ggtgcttcct ctgtagtagg
     6061 tgttgatatt tctcataaaa tgctcgaagt agcaaaagga aaaacccatt ttccacagat
     6121 tgaatatgaa tgctgtgcca tagaagatgt ggatttccca gaggagagct ttgatgtaat
     6181 actaagttcg cttgcgtttc attatgtagc agactatgag aatttaataa aaaagatata
     6241 taggatgctg aaggctggtg gcaatttagt ttttacagtt gaacatcctg tttttactgc
     6301 tcatggaaca caagactggt attataacga aaaaggagaa atactgcatt tcccggtgga
     6361 caattattat tatgagggca aacggacagc tatgtttttg gaagaaaagg ttacaaaata
     6421 tcatagaaca ctgaccacat atctaaatac actgctttca aatagtttta taataaatca
     6481 gattgtggag ccacagccgc cagagaacat gatggatatt ccggggatgg cggatgaaat
     6541 gcgacgccca atgatgctga ttgtatcggc aaaaaagaag atgtaataat atagaaaaaa
     6601 taaacgagga gtatgtaaat gagatcagaa aaagaaatga tggatttagt actttcttta
     6661 gcagaacagg atgaacgtat tcgaattgtg acccttgagg ggtcacgcgc aaatattaat
     6721 atacctaaag atgaatttca ggattatgat attacatatt ttgtaagtga tatagaaccg
     6781 tttatatcta atgatgactg gcttaatcaa tttgggaata taataatgat gcaaaagccg
     6841 gaggatatgg aattattccc acctgaagaa aagggatttt cctatcttat gctatttgat
     6901 gattacaata aaattgatct taccttattg cccttggaag agttagataa ttacctaaag
     6961 ggcgataaat taataaaggt tctaattgat aaagattgta gaattaaaag ggacatagtt
     7021 ccgactgata tagattatca tgtaagaaag ccaagcgcaa gggagtatga tgattgctgc
     7081 aatgaatttt ggaatgtaac accttatgtt attaaaggat tgtgccgtaa ggaaatttta
     7141 tttgctattg atcattttaa tcagattgtt cgccatgagc tgctgagaat gatatcatgg
     7201 aaggtcggca tcgaaacagg ctttaaatta agtgtaggca agaactataa gtttattgaa
     7261 aggtatatat ccgaggattt gtgggagaaa cttttgtcca cctaccggat ggattcctat
     7321 gaaaacatat gggaagcatt atttctatgc catcaattgt tcagggcggt atccggtgag
     7381 gtggcggaaa ggcttcatta tgcctatccg gagtatgata ggaatataac aaaatatacc
     7441 agggacatgt ataaaaaata cactggtaaa accggctgcc tggatagcac atatgccgct
     7501 gatatagaag agaggcggga acagtgatta cagaaatgaa agcagggcac ctgaaagata
     7561 tcgataaacc cagcgaacca tttgaggtga taggtaagat tataccgagg tatgaaaacg
     7621 agaattggac ctttacagaa ttactctatg aagcgccata tttaaaaagc taccaagacg
     7681 aagaggatga agaggatgag gaggcagatt gccttgaata tattgacaat actgataaga
     7741 taatatatct ttactaccaa gacgataaat gcgtcggaaa agttaaactg cgaaaaaatt
     7801 ggaaccggta cgcttatata gaagatatcg ccgtatgtaa ggatttca
//
LOCUS       DASHXG010000197         7848 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.094, whole genome shotgun sequence.
ACCESSION   DASHXG010000197 DASHXG010000000
VERSION     DASHXG010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.094"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            352..522
                     /locus_tag="U2R59_002994"
     CDS             352..522
                     /locus_tag="U2R59_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967295.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            536..1138
                     /locus_tag="U2R59_002995"
     CDS             536..1138
                     /locus_tag="U2R59_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967296.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1154..1831
                     /locus_tag="U2R59_002996"
                     /pseudo
     CDS             1154..1831
                     /locus_tag="U2R59_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2142..2306
                     /locus_tag="U2R59_002997"
                     /pseudo
     CDS             2142..2306
                     /locus_tag="U2R59_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
     gene            2343..2639
                     /locus_tag="U2R59_002998"
     CDS             2343..2639
                     /locus_tag="U2R59_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HEM8967297.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2640..3056
                     /locus_tag="U2R59_002999"
     CDS             2640..3056
                     /locus_tag="U2R59_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HEM8967298.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3076..4620
                     /locus_tag="U2R59_003000"
     CDS             3076..4620
                     /locus_tag="U2R59_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967299.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4763..4987
                     /locus_tag="U2R59_003001"
     CDS             4763..4987
                     /locus_tag="U2R59_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEM8967300.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5002..5871
                     /locus_tag="U2R59_003002"
     CDS             5002..5871
                     /locus_tag="U2R59_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HEM8967301.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5852..6586
                     /locus_tag="U2R59_003003"
     CDS             5852..6586
                     /locus_tag="U2R59_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEM8967302.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6619..7527
                     /gene="ant(6)"
                     /locus_tag="U2R59_003004"
     CDS             6619..7527
                     /gene="ant(6)"
                     /locus_tag="U2R59_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HEM8967303.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSASEYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7524..>7848
                     /locus_tag="U2R59_003005"
     CDS             7524..>7848
                     /locus_tag="U2R59_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967304.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDF"
BASE COUNT         2796 a         1209 c         1698 g         2145 t
ORIGIN      
        1 caagaagcat tttattctag cttaatttga caaatcatac tatgatacgt gtttgttttt
       61 ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt aagattttaa ttaattatta
      121 gggggagaag gagagagtag cccgaaaact tttagttggc ttggactgaa cgaagtgagg
      181 gaaaggctac taaaacgtcg aggggcagtg agagcgaagc gaacacttga tcttttaagt
      241 tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc taatatggtt ttagcagtat
      301 aattgacttg gtgaataggt catttaagtt gggcataata ggaggagtaa aatgaaaaaa
      361 tttatttatc gagttttaga aaatgacgaa gtggtggcta tttttaatga gcaacaatat
      421 gcgcaagatt ttatcgctta cgaaaagaca atttctgata agcaatttga aattgaaaaa
      481 gtagatatag ctgattggtt attgcaaccg agagaatttt agaggttggt tgaaaatggc
      541 taaaattggt tatgcacgtg tcagtagcaa agaacagaac ttagatagac aactgaaagc
      601 gttagagggc gtttctaagg tcttttcaga caaattaagc ggtcaatcgg tcgaacgccc
      661 acaattacaa gctatgctta actatattcg tgaaggggat atagttgttg ttactgaatt
      721 agatcgatta ggacgaaata ataaagaatt aacagaattg atgaatcaaa ttcaaattaa
      781 gggggcaacc ctggaagtct taaatttacc ctcaatgaat ggtattgaag atgaaaattt
      841 aagacggctg attaataatt tagtgattga attgtataag taccaagcgg aatctgaacg
      901 caaacgaatt aaagaacgcc aagcccaagg aattgaaatt gctaagaaaa aaggaaaatt
      961 caaagggcga caacctaaat tcaaagaaaa tgatccacgt ttacaacacg ctttcgattt
     1021 atttttgaat ggttgttccg ataaagaagt tgaagaacaa actggaatta atcgccgaac
     1081 gtttagaagg tatcgatcaa gatacaacgt gacagtagat caaagaaaaa aacaatgaaa
     1141 agagggatag ttaatgagta cggttatttt agctgaaaaa ccaagccagg cattagccta
     1201 cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat tttgagatca aagacccact
     1261 atttacagat gaaacgttta tcacctttgg ttttgggcat ttagtcgaat tagcagaacc
     1321 aggtcattat aacgaaaagt ggcagaactg gaaacttgaa tctttgccga tttttcctga
     1381 tcgatacgat tttgaagttg caaaagataa gggaaagcag tttaaaattg ttgctgaact
     1441 tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc gacagagaag gtgaaaatat
     1501 cgcctggtcg attatccata aagcaaatgc cttttctaaa gataaaacgt ataaaagatt
     1561 atggatcaat agcttagaaa aagatgtgat ccgaagcggt tttcaaaatt tgcaaccagg
     1621 aatgaattac tatccctttt atcaagaagc gcaaacacgc caaattgccg attggttgat
     1681 cggcatgaac gcaagccctt tatatacctt gaatttacaa caaaaaggcg tacaaggtac
     1741 attttcatta ggacgtgtac aaacaccgac tttatatctc atttatcaac gccaggaagc
     1801 aatagaaaac tttaaaaaag aacctttttt cctgaataat tcatagtttt actaatagtc
     1861 tttcctaaca ttgatttaat agtctttaaa gtattctgct tcatcaccca ttaggtgatg
     1921 aaaaaagaac ccctttctga tttagcggac aaatactttg acctaatctc agaagatata
     1981 aaagaaaaaa taataaaata tccgatttat actttgtata aagaactaaa gtagttagca
     2041 aatcatttac agcaaatcac tatgttccac ataccatttt acatacttac cttatccacg
     2101 acacatgttg agatagtatc gaagataaag aaagttgctc catgttgttt ttgcgagatg
     2161 gggaaatcaa agccacattg acaaccatga tgaataagct tgctttcagt cataagctaa
     2221 tcctagaacc acttttcaag tcagttagcc aaatcgatga agaaagcgac cgtgaaagaa
     2281 tggacgctat tgataagcta atggagcaac tattggaaga acgcaatacc cttattgcac
     2341 tgatgtccaa aggtttccta gaacctgctc tttttaatca ggaacgaaat gttttagata
     2401 gtgagattaa aaatcttact accgaaaaaa caaacctggt aacgaactct gcgagtgggg
     2461 ttttgcgagc aaacgagata aaggacctca ttaattatgt gtcagcagat aattttaatg
     2521 gtgactacac ggaagaacta tttgaagaat ttgtagtgaa catcattgta aattccaggg
     2581 atgagctgac attcaatttg aaatgcggtc tttccctgaa agaaaaggtg gtgagataaa
     2641 tggcatatat tccatatgga tacaaaattc aagatggagt ggttactgtc gatgaaaagg
     2701 cagcaggtca agtaaaggta ttctttgaga aatacatatc aggactatcc cttacagtgg
     2761 ctggcgaaca ggcaggtatt gaaaagacac attctgtgat ggggcgcatt ttgaaaaacg
     2821 tcaactacct tggaaatgat acgtatccag caattattga taaagagata tttgataaag
     2881 ctgaagaagt tagagataaa cgtgcaaagg atttaggacg agtggtagag cttgccgctt
     2941 tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa ggcagataat aagatgccag
     3001 tggatccttt tgaacgagca gaatacttat acagtctgat agaaagcgag gaataaagtg
     3061 acagagaaaa atataatggt tattcctgct cgtaaaagag taggaagtac agccgcaaaa
     3121 gaaaagataa agaaacttcg tgttgctgcc tattgccgtg tttctacaga aacagaagaa
     3181 caaaattcta gctatgaggt tcaggtctca cactatacag agtttataaa gaaaaataat
     3241 gaatgggagt ttgctggcat ctttgcagat gatggtatct ctggtacgaa cactaaaaag
     3301 cgtgacgaat ttaatcgcat gattgcagag tgtatggacg gtaacatcga catggttatt
     3361 acaaaatcca tcagccgatt tgcgcgtaac accctagact gccttcaata cattagacag
     3421 ctcaaggata agaacatatc agtttatttt gagaaagaga acatcaacac cacggatgcc
     3481 aaaggtgagg ttttgctgac tattatggca tctttggcac agcaggaaag ccagagcctt
     3541 tcacaaaacg ttaagcttgg gctacagtac cgataccaac aaggaaaggt gcaggtcaac
     3601 cataagcgat ttatgggcta cacgaaagat gaagatggaa atttaactat tgtccccgaa
     3661 gaagctgaga ttatcaaacg catctaccga gaataccttg agggtcagag tctagtgggc
     3721 attggtcgag cccttgaaaa ggatggtatt ttaacagcag cgggaaaacc aagatggcga
     3781 ccagaatcag ttaagaagat acttcaaaac gaaaaataca tcggagatgc ccttctgcaa
     3841 aagactgtca cagtagattt tctgaccaag aaacgagtga aaaatgaagg gcatgttccc
     3901 caatattatg ttgaaaatag ccatgaagcg attattccta aagagttatt tttgcaggcg
     3961 caagaagaaa ttcatcggag aagcaatatc tacacaggag aaggcaagaa caaaagaatt
     4021 tacagtagca agtacgcttt aagtgccatc accttctgtg gagattgtgg cgatatttat
     4081 agacgggtct attggaatat ccacggaaga aaagaatttg tctggcgatg cgtgactaga
     4141 atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa aagaagatga actttatggt
     4201 gcagtaatga ctgcgattaa taagctactt gcaggtggga acaatatgat aaagacactg
     4261 gaagagaata ttcatgctgt gattggcgaa accacagaat accaaatttc agagattaac
     4321 aactcactag aggaaaaaca aaaagaacta atcaagctgg cgaacaaggg tcaagactat
     4381 gaccacttag cagatgagat tgatgagctg agagacaagc gacagatcct tttagtagaa
     4441 gatgcctccc tcagtggcga gaacgagcga atcaatgagc tgattgaatt tatccgcaag
     4501 aacaaattcc gcaccttaga atatgatgat aagcttgtaa ggaagataat ccagagcgtt
     4561 acagtctatg aaggccactt cgtcatagcc ttcaaatctg gcatcgaaat ggaaatatga
     4621 aaaccagaag taaatagccc atgactctac agtagagttg tgggttttct tttgcttgct
     4681 gattataata atattttaat aactattgtg tttatcaacc aaatggttta taatattctt
     4741 agcgtaaact tggaggtgct gtatgactac ggcagaaatg attaaagaac tgtgtgagca
     4801 aatgaatata agtgtttccg aacttgctag acgtattggc cagactccac agaatttcaa
     4861 taaaaaatta caacgagaaa cagtaacctt ggatgagttg aaggccattg ctgatgtgct
     4921 aggtgtcaag tttgtgcagg catttatttt accagatgga gaagaaataa aaatatctaa
     4981 cgaataaagg aggatgttta tatggtaggt aatgttattc aaatagtaac agagaaatta
     5041 tcatctttgc cttttataga aggcatcgta ttagggggct cacgtgcaag aggcacccat
     5101 acagaaaatt ctgatataga tatcggaatc tattacaatt cagactcatt tgacctgaca
     5161 gcgattaatc aaattgctac agagttggat gatgagaata gaaacaacct tgttgtacct
     5221 cccggagcgt ggggtgattg ggttaatggc ggtggatggt tagttataaa cgggtgtcat
     5281 gttgacttga tattacgtga tataaaacgg gtggaacaaa taatcaaaga tacggagcaa
     5341 ggaattgtta ctgccaatta tcagaccggg catccccatg gttatataag tgctatgtat
     5401 cgtggagaat tagcgattag taaaatacta tatgctaaga acgaaagctt atgcgaatta
     5461 aaaaagcagg cagaaattta ccctactgct ctaaagaaaa gcttgatgaa cttttttata
     5521 tttgaagctg aattctcttt aatgtttgta aaagcaaatg cgggggcaga ggataaatat
     5581 tatattgcag gccatgtttt tcgtattatt tcatgcttaa atcaagtact atttgcatgt
     5641 aataatgctt attgcattaa cgaaaagaaa gctataaaac tgcttgaaac ttttgaatat
     5701 aaacctgaaa aatatgccga aagagttaat catatttttg aagtactcgg tctttctctt
     5761 tttgaatgct acgacatgac cgagaaactt tataaagaag tgaatgaaat tgtatcggag
     5821 ataaataact ttttaaacga ggagagttca gatgaaagaa aacaaatatg atgataatat
     5881 attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa ggactggctg gtgcgggaga
     5941 atgggagact ttgaaaaaga tgctacctga ttttaagggt aagcgtgtgc ttgatttagg
     6001 atgcggctat ggatggcact gtatatatgc gatggaaaac ggtgcttcct ctgtagtagg
     6061 tgttgatatt tctcataaaa tgctcgaagt agcaaaagga aaaacccatt ttccacagat
     6121 tgaatatgaa tgctgtgcca tagaagatgt ggatttccca gaggagagct ttgatgtaat
     6181 actaagttcg cttgcgtttc attatgtagc agactatgag aatttaataa aaaagatata
     6241 taggatgctg aaggctggtg gcaatttagt ttttacagtt gaacatcctg tttttactgc
     6301 tcatggaaca caagactggt attataacga aaaaggagaa atactgcatt tcccggtgga
     6361 caattattat tatgagggca aacggacagc tatgtttttg gaagaaaagg ttacaaaata
     6421 tcatagaaca ctgaccacat atctaaatac actgctttca aatagtttta taataaatca
     6481 gattgtggag ccacagccgc cagagaacat gatggatatt ccggggatgg cggatgaaat
     6541 gcgacgccca atgatgctga ttgtatcggc aaaaaagaag atgtaataat atagaaaaaa
     6601 taaacgagga gtatgtaaat gagatcagaa aaagaaatga tggatttagt actttcttta
     6661 gcagaacagg atgaacgtat tcgaattgtg acccttgagg ggtcacgcgc aaatattaat
     6721 atacctaaag atgaatttca ggattatgat attacatatt ttgtaagtga tatagaaccg
     6781 tttatatcta atgatgactg gcttaatcaa tttgggaata taataatgat gcaaaagccg
     6841 gaggatatgg aattattccc acctgaagaa aagggatttt cctatcttat gctatttgat
     6901 gattacaata aaattgatct taccttattg cccttggaag agttagataa ttacctaaag
     6961 ggcgataaat taataaaggt tctaattgat aaagattgta gaattaaaag ggacatagtt
     7021 ccgactgata tagattatca tgtaagaaag ccaagcgcaa gtgagtatga tgattgctgc
     7081 aatgaatttt ggaatgtaac accttatgtt attaaaggat tgtgccgtaa ggaaatttta
     7141 tttgctattg atcattttaa tcagattgtt cgccatgagc tgctgagaat gatatcatgg
     7201 aaggtcggca tcgaaacagg ctttaaatta agtgtaggca agaactataa gtttattgaa
     7261 aggtatatat ccgaggattt gtgggagaaa cttttgtcca cctaccggat ggattcctat
     7321 gaaaacatat gggaagcatt atttctatgc catcaattgt tcagggcggt atccggtgag
     7381 gtggcggaaa ggcttcatta tgcctatccg gagtatgata ggaatataac aaaatatacc
     7441 agggacatgt ataaaaaata cactggtaaa accggctgcc tggatagcac atatgccgct
     7501 gatatagaag agaggcggga acagtgatta cagaaatgaa agcagggcac ctgaaagata
     7561 tcgataaacc cagcgaacca tttgaggtga taggtaagat tataccgagg tatgaaaacg
     7621 agaattggac ctttacagaa ttactctatg aagcgccata tttaaaaagc taccaagacg
     7681 aagaggatga agaggatgag gaggcagatt gccttgaata tattgacaat actgataaga
     7741 taatatatct ttactaccaa gacgataaat gcgtcggaaa agttaaactg cgaaaaaatt
     7801 ggaaccggta cgcttatata gaagatatcg ccgtatgtaa ggatttca
//
LOCUS       DASHXG010000198         5851 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.109, whole genome shotgun sequence.
ACCESSION   DASHXG010000198 DASHXG010000000
VERSION     DASHXG010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.109"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            322..1014
                     /locus_tag="U2R59_003006"
     CDS             322..1014
                     /locus_tag="U2R59_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEM8967305.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="U2R59_003007"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="U2R59_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HEM8967306.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..3862)
                     /locus_tag="U2R59_003008"
     CDS             complement(1910..3862)
                     /locus_tag="U2R59_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HEM8967307.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3869..4105)
                     /locus_tag="U2R59_003009"
     CDS             complement(3869..4105)
                     /locus_tag="U2R59_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967308.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4507..4797
                     /locus_tag="U2R59_003010"
     CDS             4507..4797
                     /locus_tag="U2R59_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEM8967309.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            5511..5813
                     /locus_tag="U2R59_003011"
                     /pseudo
     CDS             5511..5813
                     /locus_tag="U2R59_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1997 a          925 c         1010 g         1919 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     3481 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     3541 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     3601 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     3661 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     3721 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     3781 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     3841 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     3901 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3961 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     4021 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     4081 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     4141 accattttaa cacaccaatt tgcattccta caataattat ttcacgttcg catttttata
     4201 tacattttaa cttacatttt gtggtgtaaa ttaacaacaa acgttgattt aacaataaaa
     4261 aacgagtatc aaattcagtt gcaatttgat actcatttag gtttacattt tcactttttg
     4321 tactccaaaa ctgaactact taaatctata ctgctgcctc ttttttttag tacatgtcct
     4381 tcatcttcgc aggaagtgcc aatatgattt taagaaaggt aatagacaaa aagtcaaaaa
     4441 gataaaacag agtttcttct ttacaaaggg aatgtatgtt cgtataatgg tattgaggtg
     4501 aaggttatgg agaaaaaata tggaacagta gataagatcc gtactttgca agttagtgcc
     4561 agaccgttga tccgtttcag tttaaatggg gtcaattgtt tgattgcttc ccatagtttg
     4621 aacttcctag ctgaagtaga cgaagggatg aagttagtcg ttacaggtta ttataataat
     4681 agaaagcaat ttgttgtgag atcctatcat gtgttaggga aacccaaaat tgtggtagaa
     4741 tatgagaaaa gtctataccc aagaaaaaag gtccgacaag atgaaagaat aaactagaaa
     4801 acaagcggct gagacaaaaa tgtcctagcc gcttgttttg gaaagatgga tgcagacgat
     4861 gggatttgaa cccacacgag catacgctca caagaacctc aatctatata taactacatg
     4921 tatttaagta tttgtgatga atcactaaac tttccaaact catttgaggg atattgctta
     4981 aagattgaac agatcaattc gaagccctat tagtattcgc tcaatggggg gatcagaggc
     5041 cataaaaaga gactagtcat tactagtctc aggtagtgga attgtaggat tttaaacgtt
     5101 cctggagagt accggtatgt aactcgaaga ggtgattatc atagtcgtaa aagtaaattg
     5161 aagaagcctc gcctttcaca cgagaacgtc ctggttcgac agttaaacct aacatttgga
     5221 tttttgagac aaacgaatct atatcttgtt cgtcaatttt aaaagcaata tgattgtatg
     5281 tctttggcag tttattcgac gaattctgca ttactgcaat ccataggtcc ttaactaaga
     5341 aaaatttttc tggatataat gaaaattttt ttgttgacta tcgtagattt cttttgcatc
     5401 aaataaggta tttaacaatt aagtatttaa aagataactt ttaagttatc tttaagtaat
     5461 gcttaaagct atgttatact ctattaggaa atataagaag gagtataaaa atgaacaaac
     5521 ataatagaaa aataacgaat aacaaagaac tgatcttgtt actaataggg atttggggta
     5581 tctttttact ctttaatatg tatatgccga ctatgagagc ggatgacgta gtttatgcaa
     5641 gtagattaga tgaacttggc tatttgggtg cttcgataga acattataag acatggagtt
     5701 caagaattat tatagaacta ttcttaatgt tcttttctaa acactttatg ctatggaaat
     5761 tattaaattc tacgattatg ttaggaattg tagtattact ttgcaagtat gttgagagta
     5821 taaaatattt tgtgtaaatg aaaaaatcca t
//
LOCUS       DASHXG010000199         4997 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.116, whole genome shotgun sequence.
ACCESSION   DASHXG010000199 DASHXG010000000
VERSION     DASHXG010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.116"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            complement(30..2180)
                     /locus_tag="U2R59_003012"
                     /pseudo
     CDS             complement(30..2180)
                     /locus_tag="U2R59_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2326..2901
                     /locus_tag="U2R59_003013"
     CDS             2326..2901
                     /locus_tag="U2R59_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEM8967310.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3115..3810
                     /gene="vanR"
                     /locus_tag="U2R59_003014"
     CDS             3115..3810
                     /gene="vanR"
                     /locus_tag="U2R59_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HEM8967311.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            3788..4942
                     /locus_tag="U2R59_003015"
     CDS             3788..4942
                     /locus_tag="U2R59_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HEM8967312.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         1561 a          939 c          967 g         1530 t
ORIGIN      
        1 aattttcttc tttcagcttt ttatttccca cttgtaaatc ggtagatggt ggctcctttt
       61 ccagttccat aatgtggatt tgcatctgca tgtagtgatg aaacacctag ctgcattctc
      121 ataccatctg acgaagatgt tgtaccgtcg ccccaataga aaggcaattg taatttatga
      181 tgaaagttta ctaatatggc ttgggcttta ttcatggcat cttcatacat gcgccattga
      241 gatacattgg ctagttgctt atatgtaagt ccgggtgtgg cttcggccat cttgctcaag
      301 ccaatattca ttcccattcc taaaagggca gccatgataa tgattgtttc ttccttatct
      361 ggttttcgat tattggaagc atgagtgaat tgctcatgaa atcctgttat atgggccaca
      421 tccatgagta aatcagttaa ttttattctt ggtagcatct gataaaggct tgcactaaat
      481 ttttttgctt cttctggaac atctttttct aagcgtgcaa gtgatagctt tcctttttca
      541 agagaaaccc catctaactt attggaattg gcagctaacc actttaacct ttcattaaag
      601 ctgctggttc tctccgttat ataatcttcg aatgataaac taactgataa tctcgtattc
      661 cccttcgatt gattccatgt atcttccgaa aacaaatatt cctcaaaatc cctatattgt
      721 ctgctgccaa caatggaaac atctcctgcc cgaacatgct cccgaagttc tgttaaaaca
      781 gccatttcat agtaatgacg attaattgtt gtaccatcat cctcgtataa atgtcttttc
      841 catcgttttg aaataaaatc cacaggtgag tcatcaggca cttttcgctt tccagattcg
      901 ttcattcctc ggataatctc aacagcttgt aaaagtggct catttgcctt tgtagaatga
      961 aattccaata ctcttaatag cgttggcgta tattttctta gtgaataaaa ccgtttttgc
     1021 agtaagtcta aataatcata gtcggcagga cgtgcaagtt cctgagcctc ttctactgaa
     1081 gagacaaagg tattccattc aataaccgat tctaaaacct taaaaacgtc taatttttcc
     1141 tctcttgctt taattaatgc ttgtccgatg ttcgtaaagt gtataacttt ctcatttagc
     1201 tttttaccgt tttgtttctg gatttcctct tgagccttac gaccttttga taacaaacta
     1261 agtatttgcc tatcatgaat ttcaaacgct ttatccgtta gctcctgagt aagttgtaat
     1321 aaatagatgg ttaatatcga ataacgttta ttttcttgaa agtcacggaa tgcatacggc
     1381 tcgtatcttg agcctaagcg agacagctgc aacaggcggt tacggtgcaa atgactaatt
     1441 tgcactgttt ctaaatccat tcctcgtatg tattcgagtc gttctattat ttttagaaaa
     1501 gtttcgggtg aaggatgacc cggtggctct tttaaccaac ccaatatcgt tttattggat
     1561 tcggatggat gctgcgaggt aataatccct tcaagctttt ctttttgctc atttgttaga
     1621 gatttactaa ccgtattaaa tagcttcttt tcagccattg cccttgcttc ccacaccatt
     1681 ctttcaagtg tagtgatagc aggcagtata attttgtttt ttcttagaaa atctatgcat
     1741 tcatgcagta gatgaatggc atcaccattt tccaaagcta attgatgaag gtacttaaat
     1801 gtcattcgat attcactcag ggtaaaagtt acaaagtcgt attcacttcg aatttctttc
     1861 aaatgatccc aaagtgtatt ttccctttga ggataatgat caagcgagga tggactaaca
     1921 ccaatctgtt tcgatatata ttgtatgacc gaatctggga tgcttttgat atgagtgtat
     1981 ggccaaccgg gataccgaag aacagctaat tgaacagcaa atcctaaacg gttttcttcc
     2041 ctccttcgct tattaactat ttctaaatcc cgtttggaaa aagtgaagta ggtccccagt
     2101 atccattcat cttcagggat ttgcataaaa gcctgtctct gttccggtgt aagcaattct
     2161 ctacctctcg caattttcat tcagtatcat tccatttctg tattttcaat ttattagttc
     2221 aattatatat caatagagtg tactctattg atacaaatgt agtagactga taaaatcata
     2281 gttaagagcg tctcataaga cttgtctcaa aaatgaggtg atattttgcg gaaaatcggt
     2341 tatattcgtg tcagttcgac taaccagaat ccttcaagac aatttcagca gttgaacgag
     2401 atcggaatgg atattatata tgaagagaaa gtttcaggag caacaaagga tcgcgagcaa
     2461 cttcaaaaag tgttagacga tttacaggaa gatgacatca tttatgttac agacttaact
     2521 cgaatcactc gtagtacaca agatctattt gaattaatcg ataacatacg agataaaaag
     2581 gcaagtttaa aatcactaaa agatacatgg cttgatttat cagaagataa tccatacagc
     2641 caattcttaa ttactgtaat ggctggtgtt aaccaattag agcgagatct tattcggatg
     2701 agacaacgtg aagggattga attggctaag aaagaaggaa agtttaaagg tcgattaaag
     2761 aagtatcata aaaatcacgc aggaatgaat tatgcggtaa agctatataa agaaggaaat
     2821 atgactgtaa atcaaatttg tgaaattact aatgtatcta gggcttcatt atacaggaaa
     2881 ttatcagaag tgaataatta gccattctgt attccgctaa tgggcaatat ttttaaagaa
     2941 gaaaaggaaa ctataaaata ttaacagcct cctagcgatg ccgaaaagcc ctttgataaa
     3001 aaaagaatca tcatcttaag aaattcttag tcatttatta tgtaaatgct tataaattcg
     3061 gccctataat ctgataaatt attaagggca aacttatgtg aaagggtgat aactatgagc
     3121 gataaaatac ttattgtgga tgatgaacat gaaattgccg atttggttga attatactta
     3181 aaaaacgaga attatacggt tttcaaatac tataccgcca aagaagcatt ggaatgtata
     3241 gacaagtctg agattgacct tgccatattg gacatcatgc ttcccggcac aagcggcctt
     3301 actatctgtc aaaaaataag ggacaagcac acctatccga ttatcatgct gaccgggaaa
     3361 gatacagagg tagataaaat tacagggtta acaatcggcg cggatgatta tataacgaag
     3421 ccctttcgcc cactggagtt aattgctcgg gtaaaggccc agttgcgccg atacaaaaaa
     3481 ttcagtggag taaaggagca gaacgaaaat gttatcgtcc actccggcct tgtcattaat
     3541 gttaacaccc atgagtgtta tctgaacgag aagcagttat cccttactcc caccgagttt
     3601 tcaatactgc gaatcctctg tgaaaacaag gggaatgtgg ttagctccga gctgctattt
     3661 catgagatat ggggcgacga atatttcagc aagagcaaca acaccatcac cgtgcatatc
     3721 cggcatttgc gcgaaaaaat gaacgacacc attgataatc cgaaatatat aaaaacggta
     3781 tggggggttg gttataaaat tgaaaaataa aaaaaacgac tattccaaac tagaacgaaa
     3841 actttacatg tatatcgttg caattgttgt ggtagcaatt gtattcgtgt tgtatattcg
     3901 ttcaatgatc cgagggaaac ttggggattg gatcttaagt attttggaaa acaaatatga
     3961 cttaaatcac ctggacgcga tgaaattata tcaatattcc atacggaaca atatagatat
     4021 ctttatttat gtggcgattg tcattagtat tcttattcta tgtcgcgtca tgctttcaaa
     4081 attcgcaaaa tactttgacg agataaatac cggcattgat gtacttattc agaacgaaga
     4141 taaacaaatt gagctttctg cggaaatgga tgttatggaa caaaagctca acacattaaa
     4201 acggactctg gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa aaaatgacgt
     4261 tgttatgtac ttggcgcacg atattaaaac gccccttaca tccattatcg gttatttgag
     4321 cctgcttgac gaggctccag acatgccggt agatcaaaag gcaaagtatg tgcatatcac
     4381 gttggacaaa gcgtatcgac tcgaacagct aatcgacgag ttttttgaga ttacacggta
     4441 taacctacaa acgataacgc taacaaaaac gcacatagac ctatactata tgctggtgca
     4501 gatgaccgat gaattttatc ctcagctttc cgcacatgga aaacaggcgg ttattcacgc
     4561 ccccgaggat ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct ttaacaacat
     4621 tttgaaaaac gccgctgcat acagtgagga taacagcatc attgacatta ccgcgggcct
     4681 ctccggggat gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa aagataagct
     4741 agctgccata tttgaaaagt tctataggct ggacaatgct cgttcttccg atacgggtgg
     4801 cgcgggactt ggattggcga ttgcaaaaga aattattgtt cagcatggag ggcagattta
     4861 cgcggaaagc aatgataact atacgacgtt tagggtagag cttccagcga tgccagactt
     4921 ggttgataaa aggaggtcct aagagatgta tataattttg gctctttgtc aaatgatgtt
     4981 ggtaaagaga aatctta
//
LOCUS       DASHXG010000200         3024 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.135, whole genome shotgun sequence.
ACCESSION   DASHXG010000200 DASHXG010000000
VERSION     DASHXG010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.135"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..465
                     /locus_tag="U2R59_003016"
     CDS             <1..465
                     /locus_tag="U2R59_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HEM8967313.1"
                     /translation="EYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMI
                     SWKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLFRA
                     VSGEVAERLHYAYPEYDRNITKYTRDMYKKYTGKTGCLDSTYAADIEERREQ"
     gene            462..1004
                     /gene="sat4"
                     /locus_tag="U2R59_003017"
     CDS             462..1004
                     /gene="sat4"
                     /locus_tag="U2R59_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEM8967314.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1097..1891
                     /locus_tag="U2R59_003018"
                     /note="aph(3')-IIIa"
     CDS             1097..1891
                     /locus_tag="U2R59_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEM8967315.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            2167..2739
                     /locus_tag="U2R59_003019"
     CDS             2167..2739
                     /locus_tag="U2R59_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8967316.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         1024 a          481 c          695 g          824 t
ORIGIN      
        1 gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg
       61 tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg
      121 ctgagaatga tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag
      181 aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc
      241 taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc
      301 agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg
      361 aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg
      421 gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag
      481 cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta
      541 taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt
      601 taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata
      661 ttgacaatac tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag
      721 ttaaactgcg aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg
      781 atttcagggg gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc
      841 ataaaaactt gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat
      901 tctatcataa ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg
      961 aaaacaactt tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg
     1021 aattggagtt cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag
     1081 aggaaggaaa taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga
     1141 aaaataccgc tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt
     1201 gggagaaaat gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta
     1261 tgatgtggaa cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa
     1321 ggtcctgcac tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg
     1381 cgtcctttgc tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta
     1441 tgcggagtgc atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag
     1501 cttagacagc cgcttagccg aattggatta cttactgaat aacgatctgg ccgatgtgga
     1561 ttgcgaaaac tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt
     1621 aaagacggaa aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa
     1681 catctttgtg aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc
     1741 ggacaagtgg tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga
     1801 acagtatgtc gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa
     1861 atattatatt ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt
     1921 aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact gtccatactc
     1981 tgatgtttta tatcttttct aaaagttcgc tagatagagt tctatattag agatgtaaag
     2041 agttttggtg aagaggtttg tgagtatggc ttttataacc agggtgcaat gagaagcact
     2101 aacagcagct agcttaagaa cgcataggat atacttttta tggaagtcac agaggaggaa
     2161 taaaatttga acaggattaa cagagtaacc tctattctta ttcagctgca atcaaaaaaa
     2221 ataattcctg ccaaagaaat tgcacagcga tttaatataa gcttaaggac agtttacaga
     2281 gatatccgga cacttgaaga agccggaata ccaattggat ctgaggccgg aaaaggatat
     2341 tttcttgtag agggcttcct acttccgccg gtaatgttta cagcggcgga agtgggtgca
     2401 ttgattacag cagggaaatt tttaaattgc catggagatg aatcatttat aaaggatttt
     2461 gattcagcta tgtataaaat caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag
     2521 gagttggaga acagtattaa cgtgtacagc acatctggac agaaaaatac attggcggat
     2581 aacgttattg cagcaattca gactgcaatc tgcaataaaa gggtaatatc aattcaatat
     2641 cctgcatcag gagggcaaga accggaaagc agaatgatag agcctatatc actggggttt
     2701 tatgaacaga actggtactt aatcggtttt gcaggctaag aaatgaatat aggaattttc
     2761 gtgtggatcg gattaaaagc atttgcatag aagaagagct ctgtcaaagc catgatggct
     2821 ctttggaaca aatattaaaa caaatgcttt catataaaaa actatatgcc ctacaatgcc
     2881 gttgtaaaaa ttggggaaaa gggatatatt gattttatat ctttctcaaa ataaatataa
     2941 aagcccttta aagagggctt ttatatatta atcacaaatc acttatcaca aatcacaagt
     3001 gattaatcac aaatcacttg tgat
//
LOCUS       DASHXG010000201         3024 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.136, whole genome shotgun sequence.
ACCESSION   DASHXG010000201 DASHXG010000000
VERSION     DASHXG010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.136"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            <1..465
                     /locus_tag="U2R59_003020"
     CDS             <1..465
                     /locus_tag="U2R59_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HEM8967317.1"
                     /translation="EYDDCCNEFWNVTPYVIKGLCRKEILFAIDHFNQIVRHELLRMI
                     SWKVGIETGFKLSVGKNYKFIERYISEDLWEKLLSTYRMDSYENIWEALFLCHQLFRA
                     VSGEVAERLHYAYPEYDRNITKYTRDMYKKYTGKTGCLDSTYAADIEERREQ"
     gene            462..1004
                     /gene="sat4"
                     /locus_tag="U2R59_003021"
     CDS             462..1004
                     /gene="sat4"
                     /locus_tag="U2R59_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HEM8967318.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFMGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1097..1891
                     /locus_tag="U2R59_003022"
                     /note="aph(3')-IIIa"
     CDS             1097..1891
                     /locus_tag="U2R59_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HEM8967319.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            2167..2739
                     /locus_tag="U2R59_003023"
     CDS             2167..2739
                     /locus_tag="U2R59_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HEM8967320.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         1024 a          481 c          694 g          825 t
ORIGIN      
        1 gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg
       61 tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg
      121 ctgagaatga tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag
      181 aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc
      241 taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc
      301 agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg
      361 aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg
      421 gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag
      481 cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta
      541 taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt
      601 taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata
      661 ttgacaatac tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag
      721 ttaaactgcg aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg
      781 atttcatggg gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc
      841 ataaaaactt gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat
      901 tctatcataa ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg
      961 aaaacaactt tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg
     1021 aattggagtt cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag
     1081 aggaaggaaa taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga
     1141 aaaataccgc tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt
     1201 gggagaaaat gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta
     1261 tgatgtggaa cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa
     1321 ggtcctgcac tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg
     1381 cgtcctttgc tcggaagagt atgaagatga acaaagccct gaaaagatta tcgagctgta
     1441 tgcggagtgc atcaggctct ttcactccat cgacatatcg gattgtccct atacgaatag
     1501 cttagacagc cgcttagccg aattggatta cttactgaat aacgatctgg ccgatgtgga
     1561 ttgcgaaaac tgggaagaag acactccatt taaagatccg cgcgagctgt atgatttttt
     1621 aaagacggaa aagcccgaag aggaacttgt cttttcccac ggcgacctgg gagacagcaa
     1681 catctttgtg aaagatggca aagtaagtgg ctttattgat cttgggagaa gcggcagggc
     1741 ggacaagtgg tatgacattg ccttctgcgt ccggtcgatc agggaggata tcggggaaga
     1801 acagtatgtc gagctatttt ttgacttact ggggatcaag cctgattggg agaaaataaa
     1861 atattatatt ttactggatg aattgtttta gtacctagat ttagatgtct aaaaagcttt
     1921 aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact gtccatactc
     1981 tgatgtttta tatcttttct aaaagttcgc tagatagagt tctatattag agatgtaaag
     2041 agttttggtg aagaggtttg tgagtatggc ttttataacc agggtgcaat gagaagcact
     2101 aacagcagct agcttaagaa cgcataggat atacttttta tggaagtcac agaggaggaa
     2161 taaaatttga acaggattaa cagagtaacc tctattctta ttcagctgca atcaaaaaaa
     2221 ataattcctg ccaaagaaat tgcacagcga tttaatataa gcttaaggac agtttacaga
     2281 gatatccgga cacttgaaga agccggaata ccaattggat ctgaggccgg aaaaggatat
     2341 tttcttgtag agggcttcct acttccgccg gtaatgttta cagcggcgga agtgggtgca
     2401 ttgattacag cagggaaatt tttaaattgc catggagatg aatcatttat aaaggatttt
     2461 gattcagcta tgtataaaat caaatctatt ttgaagcatg gtgaaaaaaa ctatgcacag
     2521 gagttggaga acagtattaa cgtgtacagc acatctggac agaaaaatac attggcggat
     2581 aacgttattg cagcaattca gactgcaatc tgcaataaaa gggtaatatc aattcaatat
     2641 cctgcatcag gagggcaaga accggaaagc agaatgatag agcctatatc actggggttt
     2701 tatgaacaga actggtactt aatcggtttt gcaggctaag aaatgaatat aggaattttc
     2761 gtgtggatcg gattaaaagc atttgcatag aagaagagct ctgtcaaagc catgatggct
     2821 ctttggaaca aatattaaaa caaatgcttt catataaaaa actatatgcc ctacaatgcc
     2881 gttgtaaaaa ttggggaaaa gggatatatt gattttatat ctttctcaaa ataaatataa
     2941 aagcccttta aagagggctt ttatatatta atcacaaatc acttatcaca aatcacaagt
     3001 gattaatcac aaatcacttg tgat
//
LOCUS       DASHXG010000202         3000 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.137, whole genome shotgun sequence.
ACCESSION   DASHXG010000202 DASHXG010000000
VERSION     DASHXG010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.137"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            246..1214
                     /locus_tag="U2R59_003024"
     CDS             246..1214
                     /locus_tag="U2R59_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HEM8967321.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1207..2238
                     /gene="vanA"
                     /locus_tag="U2R59_003025"
     CDS             1207..2238
                     /gene="vanA"
                     /locus_tag="U2R59_003025"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HEM8967322.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2244..2852
                     /locus_tag="U2R59_003026"
     CDS             2244..2852
                     /locus_tag="U2R59_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HEM8967323.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          894 a          574 c          723 g          809 t
ORIGIN      
        1 gatgctggtg tcatccacca acatcaaaaa gtatagagcc ataatttttt aggaaaatct
       61 caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa acggctcgtt
      121 cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag agaaagattt
      181 gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa gggttggtct
      241 taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag gcagatgcat
      301 tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg
      361 aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat aaatcagaga
      421 tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt tctacccgaa
      481 gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc actgtcgaca
      541 atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt cttatggcag
      601 tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg
      661 accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc cagataggca
      721 aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat agtcgcagcc
      781 gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc gatatcgtta
      841 cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa caaatacaga
      901 gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta gatacctatg
      961 agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat gtattggaag
     1021 gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat caatttttac
     1081 ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat tataccgagc
     1141 aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt gaaaggagac
     1201 aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga ggagcatgac
     1261 gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa atacgagccg
     1321 ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa
     1381 tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat gcacggatta
     1441 cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt ttcagctttg
     1501 catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc cggtatccct
     1561 tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt gacatacatc
     1621 gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa agatgatagg
     1681 ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc
     1741 ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga atcggcaaga
     1801 caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg
     1861 gtattgggaa acagtgccgc gttagctgtt ggcgaggtgg accaaatcag gctgcagtac
     1921 ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata
     1981 accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa
     2041 atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt acaagataac
     2101 ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata cagtcgttat
     2161 ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg cttgatcgta
     2221 ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat gaaatagtac
     2281 acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga aaaccggttg
     2341 acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg cttttgaagg
     2401 caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt taccgtccta
     2461 atcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg
     2521 aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac gtggcttcaa
     2581 aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta gacacgggtg
     2641 agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat catgcggcaa
     2701 atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca
     2761 gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac gaaccatacc
     2821 ccaatagcta ttttgatttc cccgttaaat aaacttttaa ccgttgcacg gacaaactat
     2881 ataagctaac tctttcggca ggaaacccga cgtatgtaac tggttcttag ggaatttata
     2941 tatagtagat agtattgaag aggttctgtt gcaaagtttt aaataaagaa taaaatccct
//
LOCUS       DASHXG010000203         2204 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.148, whole genome shotgun sequence.
ACCESSION   DASHXG010000203 DASHXG010000000
VERSION     DASHXG010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.148"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            366..1277
                     /locus_tag="U2R59_003027"
     CDS             366..1277
                     /locus_tag="U2R59_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HEM8967324.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1430..1915
                     /gene="vanZ"
                     /locus_tag="U2R59_003028"
     CDS             1430..1915
                     /gene="vanZ"
                     /locus_tag="U2R59_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HEM8967325.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          766 a          320 c          431 g          687 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttgaagatgt aaggcagagc
       61 gatattgcgg tcattatctg cgtgcgctgc ggcaagatag cctgataata agactgatcg
      121 catagagggg tggtatttca caccgcccat tgtcaacagg cagttcagcc tcgttaaatt
      181 cagcatgggt atcacttatg aaaattcatc tacattggtg ataatagtaa atccagtagg
      241 gcgaaataat tgactgtaat ttacggggca aaacggcaca atctcaaacg agattgtgcc
      301 gtttaagggg aagattctag aaatatttca tacttccaac tatatagtta aggaggagac
      361 tgaaaatgaa gaagttgttt tttttattgt tattgttatt cttaatatac ttaggttatg
      421 actacgttaa tgaagcactg ttttctcagg aaaaagtcga atttcaaaat tatgatcaaa
      481 atcccaaaga acatttagaa aatagtggga cttctgaaaa tacccaagag aaaacaatta
      541 cagaagaaca ggtttatcaa ggaaatctgc tattaatcaa tagtaaatat cctgttcgcc
      601 aagaaagtgt gaagtcagat atcgtgaatt tatctaaaca tgacgaatta ataaatggat
      661 acgggttgct tgatagtaat atttatatgt caaaagaaat agcacaaaaa ttttcagaga
      721 tggtcaatga tgctgtaaag ggtggcgtta gtcattttat tattaatagt ggctatcgag
      781 actttgatga gcaaagtgtg ctttaccaag aaatgggggc tgagtatgcc ttaccagcag
      841 gttatagtga gcataattca ggtttatcac tagatgtagg atcaagcttg acgaaaatgg
      901 aacgagcccc tgaaggaaag tggatagaag aaaatgcttg gaaatacggg ttcattttac
      961 gttatccaga ggacaaaaca gagttaacag gaattcaata tgaaccatgg catattcgct
     1021 atgttggttt accacatagt gcgattatga aagaaaagaa tttcgttctc gaggaatata
     1081 tggattacct aaaagaagaa aaaaccattt ctgttagtgt aaatggggaa aaatatgaga
     1141 tcttttatta tcctgttact aaaaatacca ccattcatgt gccgactaat cttcgttatg
     1201 agatatcagg aaacaatata gacggtgtaa ttgtgacagt gtttcccgga tcaacacata
     1261 ctaattcaag gaggtaagga tggcggaatg aaaccaacga aattaatgaa cagcattatt
     1321 gtactagcac ttttggggta acgttagctt tttaatttaa aacccacgtt aactaggaca
     1381 ttgctatact aatgatacaa cttaaacaaa agaattagag gaaattatat tgggaaaaat
     1441 attatctaga ggattgctag ctttatattt agtgacacta atctggttag tgttattcaa
     1501 attacaatac aatattttat cagtatttaa ttatcatcaa agaagtctta acttgactcc
     1561 atttactgct actgggaatt tcagagagat gatagataat gttataatct ttattccatt
     1621 tggcttgctt ttgaatgtca attttaaaga aatcggattt ttacctaagt ttgcttttgt
     1681 actggtttta agtcttactt ttgaaataat tcaatttatc ttcgctattg gagcgacaga
     1741 cataacagat gtaattacaa atactgttgg aggctttctt ggactgaaat tatatggttt
     1801 aagcaataag catatgaatc aaaaaaaatt agacagagtt attatttttg taggtatact
     1861 tttgctcgta ttattgctcg tttaccgtac ccatttaaga ataaattacg tgtaagatgt
     1921 ctaaatcaag caatctgatc tttcatacac ataaagatat tgaatgaatt ggattagatg
     1981 gaaaacggga tgtggggaaa ctcgcccgta ggtgtgaagt gaggggaaaa ccggtgataa
     2041 agtaaaaagc ttacctaaca ctatagtaac aaagaaagcc caattatcaa ttttagtgct
     2101 gaggaattgg tctctttaat aaatttcctt aacgttgtaa atccgcattt tcctgacggt
     2161 acccccaaac taagatttca tagatagatt ttctgataac ttta
//
LOCUS       DASHXG010000204         1459 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.158, whole genome shotgun sequence.
ACCESSION   DASHXG010000204 DASHXG010000000
VERSION     DASHXG010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.158"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            110..193
                     /locus_tag="U2R59_003029"
     CDS             110..193
                     /locus_tag="U2R59_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEM8967326.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="U2R59_003030"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="U2R59_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEM8967327.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..1434)
                     /locus_tag="U2R59_003031"
     CDS             complement(1318..1434)
                     /locus_tag="U2R59_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta-toxin"
                     /protein_id="HEM8967328.1"
                     /translation="MVQNQHQETPEFKAIQQKMESLQLPTPPIPKTPKLPGI"
BASE COUNT          521 a          231 c          236 g          471 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtc
//
LOCUS       DASHXG010000205         1371 bp    DNA     linear   BCT 12-DEC-2023
DEFINITION  TPA_asm: Enterococcus faecium strain VRE38087
            SAMN38764697-rid20546773.guided.166, whole genome shotgun sequence.
ACCESSION   DASHXG010000205 DASHXG010000000
VERSION     DASHXG010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38764697
            Sequence Read Archive: SRR27176711
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 11-DEC-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002024121.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002024121.1
            Genome Coverage       :: 67x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 12/12/2023 12:08:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,032
            CDSs (total)                      :: 2,964
            Genes (coding)                    :: 2,894
            CDSs (with protein)               :: 2,894
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 32 of 70
            Pseudo Genes (incomplete)         :: 29 of 70
            Pseudo Genes (internal stop)      :: 18 of 70
            Pseudo Genes (multiple problems)  :: 8 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38764697-rid20546773.guided.166"
                     /strain="VRE38087"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Pittsburgh, Pennsylvania"
                     /lat_lon="40.44 N 79.97 W"
                     /collection_date="2022"
                     /collected_by="University of Pittsburgh Medical Center"
     gene            265..1140
                     /locus_tag="U2R59_003032"
                     /note="aph(2'')-Ia"
     CDS             265..1140
                     /locus_tag="U2R59_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HEM8967329.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          577 a          117 c          218 g          459 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgta caagatatat taaattgatt
       61 tttgaatttt tgaaaaaaga aagaaatgct aatgcagtta ttttagaccc tcataaaaat
      121 aatccaagag caataagggc ataccaaaaa tctggtttta gaattattga agatttgcca
      181 gaacatgaat tacacgaggg caaaaaagaa gattgttatt taatggaata tagatatgat
      241 gataatgcca caaatgttaa ggcaatgaaa tatttaattg agcattactt tgataatttc
      301 aaagtagata gtattgaaat aatcggtagt ggttatgata gtgtggcata tttagttaat
      361 aatgaataca tttttaaaac aaaatttagt actaataaga aaaaaggtta tgcaaaagaa
      421 aaagcaatat ataatttttt aaatacaaat ttagaaacta atgtaaaaat tcctaatatt
      481 gaatattcgt atattagtga tgaattatct atactaggtt ataaagaaat taaaggaact
      541 tttttaacac cagaaattta ttctactatg tcagaagaag aacaaaattt gttaaaacga
      601 gatattgcca gttttttaag acaaatgcac ggtttagatt atacagatat tagtgaatgt
      661 actattgata ataaacaaaa tgtattagaa gagtatatat tgttgcgtga aactatttat
      721 aatgatttaa ctgatataga aaaagattat atagaaagtt ttatggaaag actaaatgca
      781 acaacagttt ttgagggtaa aaagtgttta tgccataatg attttagttg taatcatcta
      841 ttgttagatg gcaataatag attaactgga ataattgatt ttggagattc tggaattata
      901 gatgaatatt gtgattttat atacttactt gaagatagtg aagaagaaat aggaacaaat
      961 tttggagaag atatattaag aatgtatgga aatatagata ttgagaaagc aaaagaatat
     1021 caagatatag ttgaagaata ttatcctatt gaaactattg tttatggaat taaaaatatt
     1081 aaacaggaat ttatcgaaaa tggtagaaaa gaaatttata aaaggactta taaagattga
     1141 ttatataata tatgaaaagc tattataaaa gacattagta ttaaatagtt taaaaaaatg
     1201 aaaaataata aaggaagtga gtcaattcca gactcctgtg taaaatgcta tacaatgttt
     1261 ttaccatttc tacttatcaa aattgatgta ttttcttgaa gaataaatcc attcatcatg
     1321 taggtccata agaacggttc tgttgcaaag ttttaaatct actatcaaat a
//
